Trends in Biotechnology

Article	Citations
Unlocking the potential of stem-cell-derived ‘synthetic’ embryo models	260
Advisory Board and Contents	229
(R)evolution-on-a-chip	219
Human Blood–Brain Barrier on a Chip: Featuring Unique Multicellular Cooperation in Pathophysiology	214
Subscription and Copyright information	168
Potency Meets Precision in Nano-optimized Chemotherapeutics	138
Scalable tissue biofabrication via perfusable hollow fiber arrays for cultured meat applications	118
Microalgae: a revolution for salt-affected soil remediation	117
Healing wounds with plasma-activated hydrogel therapy	112
SynMADE: synthetic microbiota across diverse ecosystems	111
Electronic plants: the future of agriculture and urban ecosystems?	110
Smart Nucleic Acids as Future Therapeutics	106
Phytohormones: novel strategy for removing emerging contaminants and recovering resources	106
Manipulating immune activity of macrophages: a materials and mechanics perspective	101
Analyzing and understanding the robustness of bioprocesses	99
Smart materials: rational design in biosystems via artificial intelligence	95
Designing Artificial Cells towards a New Generation of Biosensors	90
Vibrio natriegens as a host for rapid biotechnology	89
The green revolution of food waste upcycling to produce polyhydroxyalkanoates	89
Enzyme discovery and engineering for sustainable plastic recycling	87
Does RNAi-Based Technology Fit within EU Sustainability Goals?	79
Prime editing: advances and therapeutic applications	79
Engineering biology approaches to modulate bacterial biofilms	78
Food Waste: A Promising Source of Sustainable Biohydrogen Fuel	77
Advisory Board and Contents	76

Subscription and Copyright information	74
Advisory Board and Contents	74
Towards biomanufacturing of cultured meat	73
Subscription and Copyright information	73
Mini-bones: miniaturized bone in vitro models	72
Printhead on a chip: empowering droplet-based bioprinting with microfluidics	71
Beyond waste: understanding urine’s potential in precision medicine	70
Translational organoid technology – the convergence of chemical, mechanical, and computational biology	69
Next-generation digital biomarkers: continuous molecular health monitoring using wearable devices	68
The GPS for drug development: navigating with evidence from human populations	67
Engineering the mangrove soil microbiome for selection of polyethylene terephthalate-transforming bacterial consortia	66
Efficient genome-editing tools to engineer the recalcitrant non-model industrial microorganism Zymomonas mobilis	66
Emerging strategies to develop novel genetically encoded biosensors	63
Integrating bicarbonate-based microalgal production with alkaline sewage for ocean negative carbon emissions	63
Ocular RNA nanomedicine: engineered delivery nanoplatforms in treating eye diseases	63
Engineered Living Materials: Taxonomies and Emerging Trends	62
Manufacturing innovation to drive down cell therapy costs	62
Molecular design of microalgae as sustainable cell factories	61
Machine learning in bioprocess development: from promise to practice	61
Multiscale models quantifying yeast physiology: towards a whole-cell model	61
Machine learning to predict de novo protein–protein interactions	61
A high-performance protein preparation approach in a single column-free step	60
Subscription and Copyright information	59
Spatial omics for accelerating plant research and crop improvement	58
Emerging supramolecular and living materials in oral medicine	58
Dynamically regulating metabolic fluxes with synthetic metabolons	57
Dynamic plasmid copy number control for synthetic biology	56
Sebum analysis as an advantageous source of biomolecular information	56
A new chapter for anti-idiotypes in low molecular weight compound immunoassays	55
Advisory Board and Contents	55
Improving awareness, understanding, and enforcement of responsibilities and regulations in Blue Biotechnology	55
Next-generation 3D-printed nutritious food derived from waste plastic and biomass	54
Advisory Board and Contents	54
Biosafety and biosecurity: treading China’s synbio tightrope	53
Ethical challenges with 3D bioprinted tissues and organs	53
Multienzymatic synthesis of nylon monomers from vegetable oils	52
Estimating environmental impacts of early-stage bioprocesses	52
3D printing of heart valves	52
Building biomaterials through genetic code expansion	51
The morally disruptive future of reprogenetic enhancement technologies	51
The LEGO® brick road to open science and biotechnology	50
Engineered bacterial therapeutics with material solutions	49
Bioprinted, spatially defined breast tumor microenvironment models of intratumoral heterogeneity and drug resistance	48
Synthetic biology for plant genetic engineering and molecular farming	48
Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy	47
Bringing the next biotechnologies to life	47
Using synthetic biology to express nitrogenase biosynthesis pathway in rice and to overcome barriers of nitrogenase instability in plant cytosol	47
Academic entrepreneurship: promise and perils	45
From academia to real-life biotech: ‘It takes a village’	45
Design principles for engineering light-controlled antibodies	45

Advances in induced anhydrobiosis for cell and gamete storage	45
Non-sterile cultivation of oleaginous organisms	44
Biotechnological approaches for producing natural pigments in yeasts	44
Harnessing lactic acid bacteria in synthetic microbial consortia	44
Next-generation industrial biotechnology for low-cost mass production of PHA	42
Rethinking techno-moral disruption in bioethics, society, and justice	42
Building Organs Using Tissue-Specific Microenvironments: Perspectives from a Bioprosthetic Ovary	42
Microbial electrosynthesis: opportunities for microbial pure cultures	41
Bioengineering human placentas: social implications of an advancing field	41
Molecular engineering of insulin for recombinant expression in yeast	41
Advisory Board and Contents	41
Advanced strategies for enzyme–electrode interfacing in bioelectrocatalytic systems	41
HHV-6 and HHV-7 reactivation in allogeneic CAR-T cell therapy	40
Long-offset paired nicking-based efficient and precise strategy for in vivo targeted insertion	40
Engineering large-scale hiPSC-derived vessel-integrated muscle-like lattices for enhanced volumetric muscle regeneration	40
Marine-derived bioactive materials as antibiofilm and antivirulence agents	39
Modeling the Human Body on Microfluidic Chips	38
Robots with a human touch	37
Merging automation and fundamental discovery into the design–build–test–learn cycle of nontraditional microbes	36
How transdisciplinarity can help biotech-driven biodiversity research	36
Microfluidic-based skin-on-chip systems for safety assessment of nanomaterials	36
Bioprocessing technology of muscle stem cells: implications for cultured meat	36
Gallium-Based Liquid Metal Particles for Therapeutics	36
Distillation for in situ recovery of volatile fermentation products	35
Apart, Together: Reflections on the COVID-19 Pandemic	35
Advisory Board and Contents	35
Transforming undergraduate laboratory courses with interlinked real-world challenges	34
An epigenetic regulator synergizes with alphavirus-mediated gene therapy via biomimetic delivery for enhanced cancer therapy	33
Light-induced programmable solid–liquid phase transition of biomolecular condensates for improved biosynthesis	33
Engineering Minds? Ethical Considerations on Biotechnological Approaches to Mental Health, Well-Being, and Human Flourishing	33
Harnessing synthetic biology to develop novel psychedelic therapies	33
pHNRhCas9NG, single expression cassette-based dual-component dual-transcription unit CRISPR/Cas9 system for plant genome editing	32
Welfare impacts of China's regulatory change toward genome-edited crops	32
CRISPR-Cas12c: a noncleaving DNA binder with minimal PAM requirement	32
In Situ 3D Printing: Opportunities with Silk Inks	31
Exploring standards for multicellular mammalian synthetic biology	31
From Innovation to Application: Bridging the Valley of Death in Industrial Biotechnology	31
Product-driven high-throughput screening of industrial filamentous actinomycetes	31
Overcoming Challenges in Expressing Iron–Sulfur Enzymes in Yeast	30
Harnessing the microbial world for human benefit	30
Biotechnology applications of proteins functionalized with DNA oligonucleotides	30
Emerging Applications of 3D Printing in Biomanufacturing	30
RNA and nanocarriers: next generation drug and delivery platform take center stage	30
Immunostimulation in experimental gas plasma therapy for breast cancer	30
Efficient and sustained photosynthetic hydrogen production by algae under high light intensity	30
OMEGA-guided DNA polymerases enable random mutagenesis in a tunable window	30
Chips, guts, and gas: unraveling volatile microbial mysteries in real time!	30
Advancing plant gene activation with CRISPR-Act3.0	30
Novel delivery systems for controlled release of bacterial therapeutics	30
Enzyme Catalyst Engineering toward the Integration of Biocatalysis and Chemocatalysis	30
Dynamic anaerobic digestion-based biorefineries for on-demand renewable energy and bioproducts in a circular bioeconomy	29
Phase-separated biomolecular condensates for biocatalysis	29
Evading and overcoming AAV neutralization in gene therapy	29
Prime editor integrase systems boost targeted DNA insertion and beyond	29
Synthetic transcription factor engineering for cell and gene therapy	29
Oxygen-Releasing Biomaterials: Current Challenges and Future Applications	28
Editing a healthier future in plants	28
Systematic development of a highly efficient cell factory for 5-aminolevulinic acid production	28
Advisory Board and Contents	28
Functionalization of Cellular Membranes with DNA Nanotechnology	28
Subscription and Copyright information	27
Chimeric antigen receptor therapy meets mRNA technology	27
The lignocellulosic biorefinery concept is sound: a commentary on Zhao et al.	27
Subscription and Copyright information	27
Hydrogen production in microbial electrolysis cells with biocathodes	27
Shaping the future US bioeconomy through safety, security, sustainability, and social responsibility	27
Intervertebral disc-on-a-chip: a precision engineered toolbox for low back pain studies	27
Yeast-based screening platforms to understand and improve human health	26
Sensors in blockchain	26
Artificial intelligence in biomaterials: a call for unified biocompatibility standards	26
Framing synthetic biology as an innovation-driven market	26
Advancements and regulations of biomanufacturing cell-based cartilage repair therapies	26
Blockchain as a frontier in biotechnology and bioenergy applications	26
Prokaryotic Argonautes for in vivo biotechnology and molecular diagnostics	25
Bringing carbon to life via one-carbon metabolism	25
Nondestructive testing of native and tissue-engineered medical products: adding numbers to pictures	25
Comparison of CRISPR/Cas and Argonaute for nucleic acid tests	25
Robustness: linking strain design to viable bioprocesses	25
Power-to-vitamins: producing folate (vitamin B9) from renewable electric power and CO2 with a microbial protein system	25
The biotechnology revolution in textile dyeing	25

Large language model for knowledge synthesis and AI-enhanced biomanufacturing	25
Advancing wheat breeding using rye: a key contribution to wheat breeding history	24
Understanding and Assisting Reproduction in Wildlife Species Using Microfluidics	23
Subscription and Copyright information	23
Advisory Board and Contents	23
Programmable embedded bioprinting for one-step manufacturing of arterial models with customized contractile and metabolic functions	23
Media representations of synthetic biology in China	23
Subscription and Copyright information	23
Cellular reprogramming and the rise of rejuvenation biotech	22
Large-scale manufacturing of human gallbladder epithelial cell products and derived hepatocytes via a chemically defined approach	22
Chairside live biotherapeutic hydrogel for comprehensive periodontitis therapy	22
Point-of-care detection devices for wound care and monitoring	22
Extracellular Vesicles in Cardiac Regeneration: Potential Applications for Tissues-on-a-Chip	22
Towards machine learning for hydrogel drug delivery systems	22
Osmotic-controlled release oral tablets: technology and functional insights	22
Synthetic biology for Taxol biosynthesis and sustainable production	22
Insights on cisgenic plants with durable disease resistance under the European Green Deal	22
From 3D Back to 2D Monolayer Stomach Organoids-on-a-Chip	22
One-pot diagnostic methods based on CRISPR/Cas and Argonaute nucleases: strategies and perspectives	22
Subscription and Copyright information	21
A ventilated perfused lung model platform to dissect the response of the lungs to viral infection	21
Robotic micromotors transforming oral drug administration	21
Validation Is Not Verification: Precise Terminology and Scientific Methods in Bioprocess Modeling	21
Subscription and Copyright information	21
CarveAdornCurate: a versatile cloud-based platform for constructing multiscale metabolic models	21
A forward-thinking biocompatibility assessment: drafting future considerations now	21
Efficiency and process development for microbial biomass production using oxic bioelectrosynthesis	21
Spatial -omics technologies: the new enterprise in 3D breast cancer models	21
EccDNA in plant-stress and biotechnological solutions in agriculture	21
Organs-on-chips: a decade of innovation	20
Additive Manufacturing Tools to Improve the Performance of Chromatographic Approaches	20
Advances in ultrahigh-throughput screening technologies for protein evolution	20
Protein–nucleic acid thermodynamic databases for specific uses	20
Gene drive in species complexes: defining target organisms	20
Quality by Design for enabling RNA platform production processes	20
Biosensors for healthcare: current and future perspectives	19
Innovation trends in industrial biotechnology	19
A pathway to improve seaweed aquaculture through microbiota manipulation	19
Driving towards digital biomanufacturing by CHO genome-scale models	19
Agricultural biotechnology for sustainable food security	19
Design of biomass-based renewable materials for environmental remediation	19
Untethered: using remote magnetic fields for regenerative medicine	19
Harnessing microbes to pioneer environmental biophotoelectrochemistry	19
Engineering next-generation oxygen-generating scaffolds to enhance bone regeneration	19