Trends in Biotechnology

Papers
(The TQCC of Trends in Biotechnology is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Unlocking the potential of stem-cell-derived ‘synthetic’ embryo models279
Advisory Board and Contents242
Human Blood–Brain Barrier on a Chip: Featuring Unique Multicellular Cooperation in Pathophysiology238
Subscription and Copyright information224
Healing wounds with plasma-activated hydrogel therapy173
Vector-free intra-airway in vivo epigenetic editing138
Microalgae: a revolution for salt-affected soil remediation136
Scalable tissue biofabrication via perfusable hollow fiber arrays for cultured meat applications132
Smart Nucleic Acids as Future Therapeutics122
Designing Artificial Cells towards a New Generation of Biosensors118
Electronic plants: the future of agriculture and urban ecosystems?114
Analyzing and understanding the robustness of bioprocesses110
Potency Meets Precision in Nano-optimized Chemotherapeutics109
Auricular repair: symphony between scaffolds and stem cells108
Engineering biology approaches to modulate bacterial biofilms98
Vibrio natriegens as a host for rapid biotechnology94
SynMADE: synthetic microbiota across diverse ecosystems92
Manipulating immune activity of macrophages: a materials and mechanics perspective85
Phytohormones: novel strategy for removing emerging contaminants and recovering resources84
(R)evolution-on-a-chip83
Food Waste: A Promising Source of Sustainable Biohydrogen Fuel82
Smart materials: rational design in biosystems via artificial intelligence80
The green revolution of food waste upcycling to produce polyhydroxyalkanoates80
Enzyme discovery and engineering for sustainable plastic recycling79
Prime editing: advances and therapeutic applications77
Advisory Board and Contents77
Advisory Board and Contents74
Subscription and Copyright information71
Subscription and Copyright information70
Towards biomanufacturing of cultured meat70
Machine learning to predict de novo protein–protein interactions69
Can protein expression be ‘solved’?69
Mini-bones: miniaturized bone in vitro models68
Beyond waste: understanding urine’s potential in precision medicine67
UFSC Biotech Network: a transdisciplinary platform for biotechnology innovation in Brazil66
The GPS for drug development: navigating with evidence from human populations66
Emerging strategies to develop novel genetically encoded biosensors65
Next-generation digital biomarkers: continuous molecular health monitoring using wearable devices64
Ocular RNA nanomedicine: engineered delivery nanoplatforms in treating eye diseases64
A high-performance protein preparation approach in a single column-free step64
Translational organoid technology – the convergence of chemical, mechanical, and computational biology64
Multiscale models quantifying yeast physiology: towards a whole-cell model64
Integrating bicarbonate-based microalgal production with alkaline sewage for ocean negative carbon emissions63
Printhead on a chip: empowering droplet-based bioprinting with microfluidics62
Machine learning in bioprocess development: from promise to practice59
Engineering the mangrove soil microbiome for selection of polyethylene terephthalate-transforming bacterial consortia59
Manufacturing innovation to drive down cell therapy costs59
Efficient genome-editing tools to engineer the recalcitrant non-model industrial microorganism Zymomonas mobilis59
Molecular design of microalgae as sustainable cell factories59
Sebum analysis as an advantageous source of biomolecular information56
Multienzymatic synthesis of nylon monomers from vegetable oils56
Subscription and Copyright information56
3D printing of heart valves56
Bioprinted, spatially defined breast tumor microenvironment models of intratumoral heterogeneity and drug resistance55
Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy55
Advisory Board and Contents55
Advisory Board and Contents54
A new chapter for anti-idiotypes in low molecular weight compound immunoassays54
Next-generation 3D-printed nutritious food derived from waste plastic and biomass54
Biosafety and biosecurity: treading China’s synbio tightrope53
Building biomaterials through genetic code expansion52
Using synthetic biology to express nitrogenase biosynthesis pathway in rice and to overcome barriers of nitrogenase instability in plant cytosol51
The LEGO® brick road to open science and biotechnology51
The morally disruptive future of reprogenetic enhancement technologies50
Ethical challenges with 3D bioprinted tissues and organs50
Frog ‘N’ Roll: novel synthetic peptides selective against Gram-negative pathogens49
Dynamic plasmid copy number control for synthetic biology49
3D extrusion bioprinting: rational bioink design and advanced fabrication techniques49
Estimating environmental impacts of early-stage bioprocesses46
Improving awareness, understanding, and enforcement of responsibilities and regulations in Blue Biotechnology46
Dynamically regulating metabolic fluxes with synthetic metabolons46
Trends in sustainable single-cell protein from non-grain feedstocks45
Engineered bacterial therapeutics with material solutions45
Emerging supramolecular and living materials in oral medicine44
Synthetic biology for plant genetic engineering and molecular farming43
Spatial omics for accelerating plant research and crop improvement43
Bringing the next biotechnologies to life43
Design principles for engineering light-controlled antibodies42
Building Organs Using Tissue-Specific Microenvironments: Perspectives from a Bioprosthetic Ovary41
Next-generation industrial biotechnology for low-cost mass production of PHA41
Academic entrepreneurship: promise and perils41
Advances in induced anhydrobiosis for cell and gamete storage41
Non-sterile cultivation of oleaginous organisms41
From academia to real-life biotech: ‘It takes a village’40
Rethinking techno-moral disruption in bioethics, society, and justice39
Rapid selection of transgenic mammalian cells via diphtheria toxin resistance39
Advanced strategies for enzyme–electrode interfacing in bioelectrocatalytic systems38
Molecular engineering of insulin for recombinant expression in yeast38
Biotechnological approaches for producing natural pigments in yeasts38
Harnessing lactic acid bacteria in synthetic microbial consortia38
Bioengineering human placentas: social implications of an advancing field37
Advisory Board and Contents37
Microbial electrosynthesis: opportunities for microbial pure cultures37
Long-offset paired nicking-based efficient and precise strategy for in vivo targeted insertion36
Engineering large-scale hiPSC-derived vessel-integrated muscle-like lattices for enhanced volumetric muscle regeneration36
HHV-6 and HHV-7 reactivation in allogeneic CAR-T cell therapy36
Advisory Board and Contents36
Modeling the Human Body on Microfluidic Chips36
How transdisciplinarity can help biotech-driven biodiversity research35
Merging automation and fundamental discovery into the design–build–test–learn cycle of nontraditional microbes35
Robots with a human touch35
Microfluidic-based skin-on-chip systems for safety assessment of nanomaterials35
Advisory Board and Contents34
Marine-derived bioactive materials as antibiofilm and antivirulence agents34
Bioprocessing technology of muscle stem cells: implications for cultured meat34
Engineering Minds? Ethical Considerations on Biotechnological Approaches to Mental Health, Well-Being, and Human Flourishing33
Efficient and sustained photosynthetic hydrogen production by algae under high light intensity33
Light-induced programmable solid–liquid phase transition of biomolecular condensates for improved biosynthesis33
Apart, Together: Reflections on the COVID-19 Pandemic33
Exploring standards for multicellular mammalian synthetic biology32
Novel delivery systems for controlled release of bacterial therapeutics32
CRISPR-Cas12c: a noncleaving DNA binder with minimal PAM requirement32
Biotechnology applications of proteins functionalized with DNA oligonucleotides32
Harnessing synthetic biology to develop novel psychedelic therapies32
An epigenetic regulator synergizes with alphavirus-mediated gene therapy via biomimetic delivery for enhanced cancer therapy32
Transforming undergraduate laboratory courses with interlinked real-world challenges32
pHNRhCas9NG, single expression cassette-based dual-component dual-transcription unit CRISPR/Cas9 system for plant genome editing32
Welfare impacts of China's regulatory change toward genome-edited crops32
Enzyme Catalyst Engineering toward the Integration of Biocatalysis and Chemocatalysis31
CRISPR/Cas-based personal glucose meters for nucleic acid detection31
Distillation for in situ recovery of volatile fermentation products31
Product-driven high-throughput screening of industrial filamentous actinomycetes31
From Innovation to Application: Bridging the Valley of Death in Industrial Biotechnology31
Advancing plant gene activation with CRISPR-Act3.030
Emerging Applications of 3D Printing in Biomanufacturing30
RNA and nanocarriers: next generation drug and delivery platform take center stage30
Organ-on-a-chip systems for modeling tumor and normal tissue microenvironments in radiotherapy research30
Chips, guts, and gas: unraveling volatile microbial mysteries in real time!29
Functionalization of Cellular Membranes with DNA Nanotechnology29
Harnessing the microbial world for human benefit29
Application of bacterial extracellular vesicles in gastrointestinal diseases29
Immunostimulation in experimental gas plasma therapy for breast cancer29
Systematic development of a highly efficient cell factory for 5-aminolevulinic acid production28
Prime editor integrase systems boost targeted DNA insertion and beyond28
OMEGA-guided DNA polymerases enable random mutagenesis in a tunable window28
Phase-separated biomolecular condensates for biocatalysis28
Synthetic transcription factor engineering for cell and gene therapy28
Dynamic anaerobic digestion-based biorefineries for on-demand renewable energy and bioproducts in a circular bioeconomy27
Evading and overcoming AAV neutralization in gene therapy27
Gas plasma technology mediates deep tissue and anticancer events independently of hydrogen peroxide27
Advisory Board and Contents26
Editing a healthier future in plants26
Subscription and Copyright information26
Oxygen-Releasing Biomaterials: Current Challenges and Future Applications26
Nondestructive testing of native and tissue-engineered medical products: adding numbers to pictures26
Subscription and Copyright information26
Advancing wheat breeding using rye: a key contribution to wheat breeding history26
Intervertebral disc-on-a-chip: a precision engineered toolbox for low back pain studies25
Shaping the future US bioeconomy through safety, security, sustainability, and social responsibility25
The lignocellulosic biorefinery concept is sound: a commentary on Zhao et al.25
Artificial intelligence in biomaterials: a call for unified biocompatibility standards24
Yeast-based screening platforms to understand and improve human health24
Sensors in blockchain24
Framing synthetic biology as an innovation-driven market24
Power-to-vitamins: producing folate (vitamin B9) from renewable electric power and CO2 with a microbial protein system24
Bringing carbon to life via one-carbon metabolism24
Advancements and regulations of biomanufacturing cell-based cartilage repair therapies24
Prokaryotic Argonautes for in vivo biotechnology and molecular diagnostics24
Large language model for knowledge synthesis and AI-enhanced biomanufacturing23
Programmable embedded bioprinting for one-step manufacturing of arterial models with customized contractile and metabolic functions23
The biotechnology revolution in textile dyeing23
Robustness: linking strain design to viable bioprocesses23
Human bone marrow organoids: emerging progress but persisting challenges23
Hydrogen production in microbial electrolysis cells with biocathodes23
Chimeric antigen receptor therapy meets mRNA technology23
Blockchain as a frontier in biotechnology and bioenergy applications23
Escherichia coli selection strains for growth-coupled metabolic engineering23
Subscription and Copyright information22
Advisory Board and Contents22
Comparison of CRISPR/Cas and Argonaute for nucleic acid tests22
Subscription and Copyright information22
Cellular reprogramming and the rise of rejuvenation biotech21
Osmotic-controlled release oral tablets: technology and functional insights21
Pollutant degradation in saline wastewater using synthetic biology21
Towards machine learning for hydrogel drug delivery systems21
Insights on cisgenic plants with durable disease resistance under the European Green Deal21
Large-scale manufacturing of human gallbladder epithelial cell products and derived hepatocytes via a chemically defined approach21
Navigating microalgae under dynamic CO2 for waste-to-energy conversion21
Media representations of synthetic biology in China21
Synthetic biology for Taxol biosynthesis and sustainable production21
Extracellular Vesicles in Cardiac Regeneration: Potential Applications for Tissues-on-a-Chip20
Point-of-care detection devices for wound care and monitoring20
One-pot diagnostic methods based on CRISPR/Cas and Argonaute nucleases: strategies and perspectives20
Protein–nucleic acid thermodynamic databases for specific uses20
Validation Is Not Verification: Precise Terminology and Scientific Methods in Bioprocess Modeling20
From 3D Back to 2D Monolayer Stomach Organoids-on-a-Chip20
Subscription and Copyright information20
EccDNA in plant-stress and biotechnological solutions in agriculture20
Agricultural biotechnology for sustainable food security20
A forward-thinking biocompatibility assessment: drafting future considerations now20
Subscription and Copyright information20
Chairside live biotherapeutic hydrogel for comprehensive periodontitis therapy20
CarveAdornCurate: a versatile cloud-based platform for constructing multiscale metabolic models20
Robotic micromotors transforming oral drug administration20
Harnessing microbes to pioneer environmental biophotoelectrochemistry20
Untethered: using remote magnetic fields for regenerative medicine19
Additive Manufacturing Tools to Improve the Performance of Chromatographic Approaches19
Gene drive in species complexes: defining target organisms19
Design of biomass-based renewable materials for environmental remediation19
Microbial cellulose production using ocean water: sustainable and cost-effective?19
Efficiency and process development for microbial biomass production using oxic bioelectrosynthesis19
Spatial -omics technologies: the new enterprise in 3D breast cancer models19
Advances in ultrahigh-throughput screening technologies for protein evolution19
Quality by Design for enabling RNA platform production processes19
Engineering next-generation oxygen-generating scaffolds to enhance bone regeneration18
Driving towards digital biomanufacturing by CHO genome-scale models18
Innovation trends in industrial biotechnology18
A ventilated perfused lung model platform to dissect the response of the lungs to viral infection18
A pathway to improve seaweed aquaculture through microbiota manipulation18
Organs-on-chips: a decade of innovation18
TRYing to evaluate production costs in microbial biotechnology18
Biosensors for healthcare: current and future perspectives18
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