Trends in Biotechnology

Papers
(The TQCC of Trends in Biotechnology is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Subscription and Copyright information279
Advisory Board and Contents272
SynMADE: synthetic microbiota across diverse ecosystems163
The green revolution of food waste upcycling to produce polyhydroxyalkanoates155
Bridging the path to multiplexed molecular diagnostics138
Unlocking the potential of stem-cell-derived ‘synthetic’ embryo models135
(R)evolution-on-a-chip133
Microalgae: a revolution for salt-affected soil remediation131
Vibrio natriegens as a host for rapid biotechnology127
Auricular repair: symphony between scaffolds and stem cells124
Electronic plants: the future of agriculture and urban ecosystems?111
Scalable tissue biofabrication via perfusable hollow fiber arrays for cultured meat applications106
Vector-free intra-airway in vivo epigenetic editing104
Smart Nucleic Acids as Future Therapeutics101
Food Waste: A Promising Source of Sustainable Biohydrogen Fuel96
Analyzing and understanding the robustness of bioprocesses96
Phytohormones: novel strategy for removing emerging contaminants and recovering resources94
Manipulating immune activity of macrophages: a materials and mechanics perspective91
Engineering biology approaches to modulate bacterial biofilms91
Prime editing: advances and therapeutic applications86
Smart materials: rational design in biosystems via artificial intelligence84
Healing wounds with plasma-activated hydrogel therapy80
Enzyme discovery and engineering for sustainable plastic recycling79
Advisory Board and Contents78
Emerging strategies to develop novel genetically encoded biosensors76
Subscription and Copyright information76
Subscription and Copyright information75
Subscription and Copyright information75
Extended human lymph node explants for evaluation of adaptive immunity74
UFSC Biotech Network: a transdisciplinary platform for biotechnology innovation in Brazil72
Nanobotic microbiomes against emerging vascular pathogens in agriculture71
Advisory Board and Contents71
The GPS for drug development: navigating with evidence from human populations71
Manufacturing innovation to drive down cell therapy costs71
Integrating bicarbonate-based microalgal production with alkaline sewage for ocean negative carbon emissions67
Translational organoid technology – the convergence of chemical, mechanical, and computational biology67
Mini-bones: miniaturized bone in vitro models66
Multiscale models quantifying yeast physiology: towards a whole-cell model65
Efficient genome-editing tools to engineer the recalcitrant non-model industrial microorganism Zymomonas mobilis65
Towards biomanufacturing of cultured meat64
A high-performance protein preparation approach in a single column-free step63
Next-generation digital biomarkers: continuous molecular health monitoring using wearable devices63
Ocular RNA nanomedicine: engineered delivery nanoplatforms in treating eye diseases63
Molecular design of microalgae as sustainable cell factories63
Machine learning in bioprocess development: from promise to practice62
Machine learning to predict de novo protein–protein interactions61
Can protein expression be ‘solved’?60
Engineering the mangrove soil microbiome for selection of polyethylene terephthalate-transforming bacterial consortia59
Printhead on a chip: empowering droplet-based bioprinting with microfluidics59
Next-generation 3D-printed nutritious food derived from waste plastic and biomass58
Advisory Board and Contents58
Beyond waste: understanding urine’s potential in precision medicine58
Improving awareness, understanding, and enforcement of responsibilities and regulations in Blue Biotechnology57
Subscription and Copyright information57
The LEGO® brick road to open science and biotechnology56
3D extrusion bioprinting: rational bioink design and advanced fabrication techniques56
Sebum analysis as an advantageous source of biomolecular information55
Advisory Board and Contents54
Advisory Board and Contents53
The morally disruptive future of reprogenetic enhancement technologies52
Frog ‘N’ Roll: novel synthetic peptides selective against Gram-negative pathogens52
Emerging supramolecular and living materials in oral medicine51
Spatial omics for accelerating plant research and crop improvement50
Using synthetic biology to express nitrogenase biosynthesis pathway in rice and to overcome barriers of nitrogenase instability in plant cytosol50
Bioprinted, spatially defined breast tumor microenvironment models of intratumoral heterogeneity and drug resistance50
3D printing of heart valves49
Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy49
Synthetic biology for plant genetic engineering and molecular farming49
Trends in sustainable single-cell protein from non-grain feedstocks48
Ethical challenges with 3D bioprinted tissues and organs47
Engineered bacterial therapeutics with material solutions47
Metabolic and immunomodulatory control of type 2 diabetes via generating cellular itaconate reservoirs by inflammatory-targeting gene-therapy nanovesicles46
Dynamically regulating metabolic fluxes with synthetic metabolons46
Dynamic plasmid copy number control for synthetic biology46
Biosafety and biosecurity: treading China’s synbio tightrope45
A new chapter for anti-idiotypes in low molecular weight compound immunoassays45
Estimating environmental impacts of early-stage bioprocesses45
Multienzymatic synthesis of nylon monomers from vegetable oils44
Harnessing Streptomyces–plant interactions for agricultural natural product discovery44
Small but mighty: emerging roles of uORFs in plants44
Building biomaterials through genetic code expansion44
One-pot production of colored bacterial cellulose44
Microbial electrosynthesis: opportunities for microbial pure cultures43
Protein–glycan engineering in vaccine design: merging immune mechanisms with biotechnological innovation43
Solar-driven PHB synthesis from wastewater by engineered semiconductor–bacteria biohybrids43
Advanced strategies for enzyme–electrode interfacing in bioelectrocatalytic systems42
From academia to real-life biotech: ‘It takes a village’41
Rethinking techno-moral disruption in bioethics, society, and justice41
Bringing the next biotechnologies to life41
Design principles for engineering light-controlled antibodies41
Biotechnological approaches for producing natural pigments in yeasts40
Next-generation industrial biotechnology for low-cost mass production of PHA40
Academic entrepreneurship: promise and perils40
Non-sterile cultivation of oleaginous organisms39
Advances in induced anhydrobiosis for cell and gamete storage38
Molecular engineering of insulin for recombinant expression in yeast38
Rapid selection of transgenic mammalian cells via diphtheria toxin resistance37
Harnessing lactic acid bacteria in synthetic microbial consortia37
Bioengineering human placentas: social implications of an advancing field37
How transdisciplinarity can help biotech-driven biodiversity research36
Subscription and Copyright information36
Engineering large-scale hiPSC-derived vessel-integrated muscle-like lattices for enhanced volumetric muscle regeneration36
Long-offset paired nicking-based efficient and precise strategy for in vivo targeted insertion36
Advisory Board and Contents36
Making cow-free caseins and casein micelles36
Computationally guided genome rewiring of Escherichia coli and its application for nanopolyethylene terephthalate (PET) biodegradation and upcycling36
Robots with a human touch36
Nanobodies: a new frontier in plant disease management36
Bioprocessing technology of muscle stem cells: implications for cultured meat35
HHV-6 and HHV-7 reactivation in allogeneic CAR-T cell therapy35
Microfluidic-based skin-on-chip systems for safety assessment of nanomaterials35
Merging automation and fundamental discovery into the design–build–test–learn cycle of nontraditional microbes35
Advisory Board and Contents35
Marine-derived bioactive materials as antibiofilm and antivirulence agents34
CRISPR screen-based mammalian cell engineering for complex biotherapeutics34
Engineered RNA nanostructures for scalable and efficient RNAi-based pesticides34
Efficient and sustained photosynthetic hydrogen production by algae under high light intensity34
Virus-like particles as modular interfaces for biomaterial functionalization33
Harnessing synthetic biology to develop novel psychedelic therapies33
Apart, Together: Reflections on the COVID-19 Pandemic33
Transforming undergraduate laboratory courses with interlinked real-world challenges33
Exploring standards for multicellular mammalian synthetic biology33
Welfare impacts of China's regulatory change toward genome-edited crops32
CRISPR-Cas12c: a noncleaving DNA binder with minimal PAM requirement32
From Innovation to Application: Bridging the Valley of Death in Industrial Biotechnology31
Novel delivery systems for controlled release of bacterial therapeutics31
Engineering M13 phages: surface and morphological strategies for programmable applications31
Product-driven high-throughput screening of industrial filamentous actinomycetes31
Distillation for in situ recovery of volatile fermentation products30
Organ-on-a-chip systems for modeling tumor and normal tissue microenvironments in radiotherapy research30
CRISPR/Cas-based personal glucose meters for nucleic acid detection30
pHNRhCas9NG, single expression cassette-based dual-component dual-transcription unit CRISPR/Cas9 system for plant genome editing30
Clinical technology advances driving in vivo CAR therapy29
An epigenetic regulator synergizes with alphavirus-mediated gene therapy via biomimetic delivery for enhanced cancer therapy29
Light-induced programmable solid–liquid phase transition of biomolecular condensates for improved biosynthesis29
Biotechnology applications of proteins functionalized with DNA oligonucleotides29
Harnessing the microbial world for human benefit28
Staying productive under pressure: systems evaluations of β-carotene production in Yarrowia lipolytica under continuous fermentation28
Advancing plant gene activation with CRISPR-Act3.028
RNA and nanocarriers: next generation drug and delivery platform take center stage28
Chips, guts, and gas: unraveling volatile microbial mysteries in real time!27
Rational bioengineering of polysaccharide in designing of microbiome modulation27
Rewiring holobiont systems with synthetic biology27
Ethical and legal considerations of digital animal models: pioneering reduction and replacement27
Phase-separated biomolecular condensates for biocatalysis27
Evading and overcoming AAV neutralization in gene therapy26
Synthetic transcription factor engineering for cell and gene therapy26
Prime editor integrase systems boost targeted DNA insertion and beyond26
Application of bacterial extracellular vesicles in gastrointestinal diseases26
Gas plasma technology mediates deep tissue and anticancer events independently of hydrogen peroxide26
Dynamic anaerobic digestion-based biorefineries for on-demand renewable energy and bioproducts in a circular bioeconomy26
Immunostimulation in experimental gas plasma therapy for breast cancer25
Sensors in blockchain25
Editing a healthier future in plants25
Yeast-based screening platforms to understand and improve human health25
Systematic development of a highly efficient cell factory for 5-aminolevulinic acid production25
Blockchain as a frontier in biotechnology and bioenergy applications25
Subscription and Copyright information25
Subscription and Copyright information25
OMEGA-guided DNA polymerases enable random mutagenesis in a tunable window25
Semi-automated biofoundry workflows for sequence coevolution-guided isoprene synthase engineering25
Harnessing piezoelectricity for musculoskeletal regeneration: microcurrents to tissue repair25
Advancements and regulations of biomanufacturing cell-based cartilage repair therapies25
Large language model for knowledge synthesis and AI-enhanced biomanufacturing24
Intervertebral disc-on-a-chip: a precision engineered toolbox for low back pain studies24
Advisory Board and Contents24
Advancing wheat breeding using rye: a key contribution to wheat breeding history24
Human bone marrow organoids: emerging progress but persisting challenges24
Shaping the future US bioeconomy through safety, security, sustainability, and social responsibility24
Next-generation electroactive biomaterials-integrated bioelectronics for advanced healthcare management24
Artificial intelligence in biomaterials: a call for unified biocompatibility standards24
Framing synthetic biology as an innovation-driven market24
The lignocellulosic biorefinery concept is sound: a commentary on Zhao et al.24
Bringing carbon to life via one-carbon metabolism24
The biotechnology revolution in textile dyeing23
Robustness: linking strain design to viable bioprocesses23
Nondestructive testing of native and tissue-engineered medical products: adding numbers to pictures23
Prokaryotic Argonautes for in vivo biotechnology and molecular diagnostics23
Programmable embedded bioprinting for one-step manufacturing of arterial models with customized contractile and metabolic functions23
Comparison of CRISPR/Cas and Argonaute for nucleic acid tests22
Power-to-vitamins: producing folate (vitamin B9) from renewable electric power and CO2 with a microbial protein system22
Osmotic-controlled release oral tablets: technology and functional insights22
Chimeric antigen receptor therapy meets mRNA technology22
Strengthening the competitiveness of EU in vitro biotechnologies22
Hydrogen production in microbial electrolysis cells with biocathodes22
Bioinspired thermoreversible bioink orchestrates focal adhesion-dependent osteogenesis22
Escherichia coli selection strains for growth-coupled metabolic engineering22
Insights on cisgenic plants with durable disease resistance under the European Green Deal22
Cellular reprogramming and the rise of rejuvenation biotech21
Subscription and Copyright information21
Synthetic biology for Taxol biosynthesis and sustainable production21
Engineering chimeric signaling proteins for microbial whole-cell biosensors: from design to deployment21
Subscription and Copyright information21
Pollutant degradation in saline wastewater using synthetic biology21
Navigating microalgae under dynamic CO2 for waste-to-energy conversion21
Large-scale manufacturing of human gallbladder epithelial cell products and derived hepatocytes via a chemically defined approach20
Towards machine learning for hydrogel drug delivery systems20
Subscription and Copyright information20
A forward-thinking biocompatibility assessment: drafting future considerations now20
Media representations of synthetic biology in China20
Chairside live biotherapeutic hydrogel for comprehensive periodontitis therapy20
Subscription and Copyright information20
New technologies for production of recombinant spider silk20
One-pot diagnostic methods based on CRISPR/Cas and Argonaute nucleases: strategies and perspectives20
Point-of-care detection devices for wound care and monitoring20
Efficiency and process development for microbial biomass production using oxic bioelectrosynthesis19
Spatial -omics technologies: the new enterprise in 3D breast cancer models19
Organs-on-chips: a decade of innovation19
A pathway to improve seaweed aquaculture through microbiota manipulation19
Microbial cellulose production using ocean water: sustainable and cost-effective?19
Gene drive in species complexes: defining target organisms19
Protein–nucleic acid thermodynamic databases for specific uses19
EccDNA in plant-stress and biotechnological solutions in agriculture19
Engineering next-generation oxygen-generating scaffolds to enhance bone regeneration19
CarveAdornCurate: a versatile cloud-based platform for constructing multiscale metabolic models19
Untethered: using remote magnetic fields for regenerative medicine18
Robotic micromotors transforming oral drug administration18
Agricultural biotechnology for sustainable food security18
Advances in ultrahigh-throughput screening technologies for protein evolution18
Harnessing microbes to pioneer environmental biophotoelectrochemistry18
Design of biomass-based renewable materials for environmental remediation18
Innovation trends in industrial biotechnology18
A ventilated perfused lung model platform to dissect the response of the lungs to viral infection18
Quality by Design for enabling RNA platform production processes18
Driving towards digital biomanufacturing by CHO genome-scale models18
Biosensors for healthcare: current and future perspectives18
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