OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Controlled Release is 86. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
A PBPK model recapitulates early kinetics of anti-PEG antibody-mediated clearance of PEG-liposomes	542
Prediction of drug capturing by lipid emulsions in vivo for the treatment of a drug overdose	390
Outside Back Cover	326
Inside Back Cover	284
In vivo self-assembled small RNA targets H19 lncRNA for the treatment of colorectal cancer	284
Full-cycle study on developing a novel structured micromixer and evaluating the nanoparticle products as mRNA delivery carriers	266
Pickering emulsion-guided monomeric delivery of monophosphoryl lipid A for enhanced vaccination	264
Inside Back Cover	251
Corrigendum to “Dissolving microarray patches loaded with a rotigotine nanosuspension: A potential alternative to Neupro® patch” [Journal of Controlled Release 372 (2024) 304–317]	250
Outside Back Cover	246
Macrophage-targeting nano-formulated bicalutamide alleviates colitis by inducing MAP3K1-mediated degradation of NLRP3	244
Outside Front Cover: Yisheng Peng et al	230
The osteogenic and angiogenic potential of microRNA-26a delivered via a non-viral delivery peptide for bone repair	224
Tumor permeable self-delivery nanodrug targeting mitochondria for enhanced chemotherapy	211
Enhanced browning of adipose tissue by mirabegron-microspheres	206
Functional nanoplatform for modulating cellular forces to enhance antitumor immunity via mechanotransduction	193
Surface-engineered mesenchymal stem cell for refractory asthma therapy: Reversing airway remodeling	186
Adaptable peptide-based therapeutics modulating tumor microenvironment for combinatorial radio-immunotherapy	182
A self-assembled graphene oxide adjuvant induces both enhanced humoral and cellular immune responses in influenza vaccine	180
Oxygen-boosted fluorinated prodrug hybrid nanoassemblies for bidirectional amplification of breast cancer ferroptosis	173
In vivo delivery of antioxidant enzymes with multi-functionalized lipid nanoparticles for sepsis therapy	171
Hypoxia-responsive oncolytic conjugate triggers type-II immunogenic cell death for enhanced photodynamic immunotherapy	169
Modified montmorillonite armed probiotics with enhanced on-site mucus-depleted intestinal colonization and H2S scavenging for colitis treatment	166
The inflammatory bowel disease and gut microbiome are restored by employing metformin-loaded alginate-shelled microcapsules	165
Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice	162

Combinatorial physical methods for cellular therapy: Towards the future of cellular analysis?	161
Nanoghosts: Mesenchymal Stem cells derived nanoparticles as a unique approach for cartilage regeneration	156
Mechanisms of uptake and transport of particulate formulations in the small intestine	155
Surface programmed bacteria as photo-controlled NO generator for tumor immunological and gas therapy	148
Dynamic versus static testing and in vivo mechanical performance of poly(glycolide-trimethylene carbonate-ε-caprolactone) delayed release implants	147
Hybrid prodrug nanoassembly for hypoxia-triggered immunogenic chemotherapy and immune modulation	147
Down-regulation of TNF-α via macrophage-targeted RNAi system for the treatment of acute inflammatory sepsis	144
An efficient (nano) silica - In glucan particles protein encapsulation approach for improved thermal stability	141
Targosomes: Anti-HER2 PLGA nanocarriers for bioimaging, chemotherapy and local photothermal treatment of tumors and remote metastases	139
Alendronate-functionalized polymeric micelles target icaritin to bone for mitigating osteoporosis in a rat model	135
A next-generation STING agonist MSA-2: From mechanism to application	134
Digging the intercellular crosstalk via extracellular vesicles: May exosomes be the drug delivery solution for target glioblastoma?	133
Identification of functional biomarkers for personalized nanomedicine in advanced breast cancer in vitro models	131
Unleashing the potential of cell biomimetic nanoparticles: Strategies and challenges in their design and fabrication for therapeutic applications	127
Intraperitoneal drug delivery systems for peritoneal carcinomatosis: Bridging the gap between research and clinical implementation	125
Transdermal carbon monoxide delivery	125
Combination of multivalent DR5 receptor clustering agonists and histone deacetylase inhibitors for treatment of colon cancer	124
Outside Back Cover	122
Hybrid nanopotentiators with dual cascade amplification for glioma combined interventional therapy	121
Mechanism exploration of intestinal mucus penetration of nano-Se: regulated by polysaccharides with different functional groups and molecular weights	120
Methodological needs in the quality and safety characterisation of nanotechnology-based health products: Priorities for method development and standardisation	120
The colon targeting efficacies of mesalazine medications and their impacts on the gut microbiome	119
Single-cell RNA transcriptome landscape of murine liver following systemic administration of mesoporous silica nanoparticles	119
Micellar paclitaxel boosts ICD and chemo-immunotherapy of metastatic triple negative breast cancer	119
Healing with precision: A multi-functional hydrogel-bioactive glass dressing boosts infected wound recovery and enhances neurogenesis in the wound bed	118
Cavitation-assisted sonothrombolysis by asymmetrical nanostars for accelerated thrombolysis	117
Impact of interferon-γ on the target cell tropism of nanoparticles	116
Conditioned media-integrated microneedles for hair regeneration through perifollicular angiogenesis	116
In-situ-formed immunotherapeutic and hemostatic dual drug-loaded nanohydrogel for preventing postoperative recurrence of hepatocellular carcinoma	115
Self-assembly hydrogels of therapeutic agents for local drug delivery	114
Nanoparticle-mediated thermal Cancer therapies: Strategies to improve clinical translatability	112
Nanotechnology-assisted intracellular delivery of antibody as a precision therapy approach for KRAS-driven tumors	109
Advance cardiac nanomedicine by targeting the pathophysiological characteristics of heart failure	108
Integrative approaches to enhance adeno-associated viral gene delivery	107
Nano-trapping CXCL13 reduces regulatory B cells in tumor microenvironment and inhibits tumor growth	107
Thermoresponsive polymeric dexamethasone prodrug for arthritis pain	104
Enhancing gene transfection of poly(β-amino ester)s through modulation of amphiphilicity and chain sequence	102
Autophagy-activating aluminum hydroxide nanovaccine for enhanced antigen presentation and anti-tumor immunity	99
Multifunctional nanoparticles potentiate in-situ tumor vaccines via reversing insufficient Photothermal therapy by disrupting tumor vasculature	98
Dasatinib and erianin co-loaded ion-responsive in-situ hydrogel for effective treatment of corneal neovascularization	98
Dual-stimulus phototherapeutic nanogel for triggering pyroptosis to promote cancer immunotherapy	98
The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs	97
Injectable nanocomposite hydrogel with cascade drug release for treatment of uveal melanoma	96
Spatiotemporally controlled Pseudomonas exotoxin transgene system combined with multifunctional nanoparticles for breast cancer antimetastatic therapy	96
Orthogonal upconversion nanocarriers for combined photodynamic therapy and precisely triggered gene silencing in combating keloids	95
ZIF-8-modified hydrogel sequentially delivers angiogenic and osteogenic growth factors to accelerate vascularized bone regeneration	95
Engineered exosomes with enhanced stability and delivery efficiency for glioblastoma therapy	94
Tagged extracellular vesicles with the RBD of the viral spike protein for delivery of antiviral agents against SARS-COV-2 infection	93
Autophagy-modulating biomembrane nanostructures: A robust anticancer weapon by modulating the inner and outer cancer environment	93
Oral mucosal vaccination using integrated fiber microneedles	92

MSC-derived extracellular vesicles as nanotherapeutics for promoting aged liver regeneration	92
Laser-assisted nanocarrier delivery to achieve cutaneous siRNA targeting for attenuating psoriasiform dermatitis	90
Complement opsonization of nanoparticles: Differences between humans and preclinical species	89
Development of a thermostable oxytocin microneedle patch	88
Bioorthogonal conjugation and responsive nanocoating of probiotics for inflammatory bowel disease	88
Topical formulation based on disease-specific nanoparticles for single-dose cure of psoriasis	88
A smart cauliflower-like carrier for astaxanthin delivery to relieve colon inflammation	87
White paper: Understanding, informing and defining the regulatory science of microneedle-based dosage forms that are applied to the skin	87
Hydrogel-forming microarray patches with solid dispersion reservoirs for transdermal long-acting microdepot delivery of a hydrophobic drug	87
Extracellular vesicles for renal therapeutics: State of the art and future perspective	87
Dendritic cell derived exosomes loaded neoantigens for personalized cancer immunotherapies	86
Melittin-incorporated nanomedicines for enhanced cancer immunotherapy	86
Accelerated blood clearance of PEGylated nanoparticles induced by PEG-based pharmaceutical excipients	86