OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Controlled Release is 87. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Prediction of drug capturing by lipid emulsions in vivo for the treatment of a drug overdose	458
Outside Back Cover	357
Single-cell RNA transcriptome landscape of murine liver following systemic administration of mesoporous silica nanoparticles	350
Inside Back Cover	329
Corrigendum to “Dissolving microarray patches loaded with a rotigotine nanosuspension: A potential alternative to Neupro® patch” [Journal of Controlled Release 372 (2024) 304–317]	313
Outside Back Cover	308
Macrophage-targeting nano-formulated bicalutamide alleviates colitis by inducing MAP3K1-mediated degradation of NLRP3	307
Outside Front Cover: Yisheng Peng et al	283
Surface-engineered mesenchymal stem cell for refractory asthma therapy: Reversing airway remodeling	277
The inflammatory bowel disease and gut microbiome are restored by employing metformin-loaded alginate-shelled microcapsules	271
Dynamic versus static testing and in vivo mechanical performance of poly(glycolide-trimethylene carbonate-ε-caprolactone) delayed release implants	241
Laser-assisted nanocarrier delivery to achieve cutaneous siRNA targeting for attenuating psoriasiform dermatitis	241
Outside Back Cover	234
Nanotechnology-assisted intracellular delivery of antibody as a precision therapy approach for KRAS-driven tumors	228
Functional nanoplatform for modulating cellular forces to enhance antitumor immunity via mechanotransduction	220
Orthogonal upconversion nanocarriers for combined photodynamic therapy and precisely triggered gene silencing in combating keloids	217
Combination of multivalent DR5 receptor clustering agonists and histone deacetylase inhibitors for treatment of colon cancer	203
Transdermal carbon monoxide delivery	194
Complement opsonization of nanoparticles: Differences between humans and preclinical species	187
Multifunctional nanoparticles potentiate in-situ tumor vaccines via reversing insufficient Photothermal therapy by disrupting tumor vasculature	181
Full-cycle study on developing a novel structured micromixer and evaluating the nanoparticle products as mRNA delivery carriers	181
A PBPK model recapitulates early kinetics of anti-PEG antibody-mediated clearance of PEG-liposomes	181
Tumor permeable self-delivery nanodrug targeting mitochondria for enhanced chemotherapy	180
Pickering emulsion-guided monomeric delivery of monophosphoryl lipid A for enhanced vaccination	177
Enhancing gene transfection of poly(β-amino ester)s through modulation of amphiphilicity and chain sequence	176

Hybrid prodrug nanoassembly for hypoxia-triggered immunogenic chemotherapy and immune modulation	176
MSC-derived extracellular vesicles as nanotherapeutics for promoting aged liver regeneration	175
The pharmacokinetic profile of mitomycin C released from an injectable supramolecular hydrogel in a rodent model	155
Collagenase-modified polydopamine nanoparticles for safe and effective vitreolysis	151
Lanthanide nanocrystals-based direct triple-state energy converters for mitophagy and ferroptosis-induced antitumor immunoreaction	150
Designing and modeling nanomedicines towards image-guided drug delivery in hematological malignancies	148
Coordinated modulation of glucose metabolism and immunity via metal-drug nanovesicles for hepatocellular carcinoma therapy	145
Outside Front Cover	141
Hypoxia-responsive oncolytic conjugate triggers type-II immunogenic cell death for enhanced photodynamic immunotherapy	137
Autophagy-activating aluminum hydroxide nanovaccine for enhanced antigen presentation and anti-tumor immunity	136
Advance cardiac nanomedicine by targeting the pathophysiological characteristics of heart failure	136
Oral mucosal vaccination using integrated fiber microneedles	136
Alendronate-functionalized polymeric micelles target icaritin to bone for mitigating osteoporosis in a rat model	134
Oxygen-boosted fluorinated prodrug hybrid nanoassemblies for bidirectional amplification of breast cancer ferroptosis	133
Autophagy-modulating biomembrane nanostructures: A robust anticancer weapon by modulating the inner and outer cancer environment	132
Optimized bacterial delivery approaches for precision immunotherapy in breast cancer models	131
The osteogenic and angiogenic potential of microRNA-26a delivered via a non-viral delivery peptide for bone repair	131
Nanoparticle-based methionine and AICAR delivery elicits a robust antitumor immune response	130
White paper: Understanding, informing and defining the regulatory science of microneedle-based dosage forms that are applied to the skin	127
A next-generation STING agonist MSA-2: From mechanism to application	127
Digging the intercellular crosstalk via extracellular vesicles: May exosomes be the drug delivery solution for target glioblastoma?	126
Self-assembly hydrogels of therapeutic agents for local drug delivery	125
Cavitation-assisted sonothrombolysis by asymmetrical nanostars for accelerated thrombolysis	122
An efficient (nano) silica - In glucan particles protein encapsulation approach for improved thermal stability	117
Impact of interferon-γ on the target cell tropism of nanoparticles	116
Integrative approaches to enhance adeno-associated viral gene delivery	114
Multifunctional delivery strategies and nanoplatforms of SN-38 in cancer therapeutics	114
Healing with precision: A multi-functional hydrogel-bioactive glass dressing boosts infected wound recovery and enhances neurogenesis in the wound bed	112
Identification of functional biomarkers for personalized nanomedicine in advanced breast cancer in vitro models	110
Surface programmed bacteria as photo-controlled NO generator for tumor immunological and gas therapy	105
A self-assembled graphene oxide adjuvant induces both enhanced humoral and cellular immune responses in influenza vaccine	104
Extracellular vesicles for renal therapeutics: State of the art and future perspective	104
Melittin-incorporated nanomedicines for enhanced cancer immunotherapy	103
An engineered dual function peptide to repair fractured bones	102
Intraperitoneal drug delivery systems for peritoneal carcinomatosis: Bridging the gap between research and clinical implementation	102
Hybrid nanopotentiators with dual cascade amplification for glioma combined interventional therapy	102
Thermoresponsive polymeric dexamethasone prodrug for arthritis pain	101
Nano-trapping CXCL13 reduces regulatory B cells in tumor microenvironment and inhibits tumor growth	101
Injectable nanocomposite hydrogel with cascade drug release for treatment of uveal melanoma	100
Metal-phenolic network-based polymeric nanocarriers facilitating antibody cytoplasmic delivery and anti-tumor effects to orthotopic breast tumors	100
Engineered exosomes with enhanced stability and delivery efficiency for glioblastoma therapy	98
Combinatorial physical methods for cellular therapy: Towards the future of cellular analysis?	97
Topical formulation based on disease-specific nanoparticles for single-dose cure of psoriasis	96
ZIF-8-modified hydrogel sequentially delivers angiogenic and osteogenic growth factors to accelerate vascularized bone regeneration	95
Hydrogel-forming microarray patches with solid dispersion reservoirs for transdermal long-acting microdepot delivery of a hydrophobic drug	94
Adaptable peptide-based therapeutics modulating tumor microenvironment for combinatorial radio-immunotherapy	93
Enhanced browning of adipose tissue by mirabegron-microspheres	93
Biomimetic reactive oxygen/nitrogen nanoscavengers inhibit “ferroptosis storm” and modulate immune targeting for acute kidney injury	93
Dasatinib and erianin co-loaded ion-responsive in-situ hydrogel for effective treatment of corneal neovascularization	93
Micellar paclitaxel boosts ICD and chemo-immunotherapy of metastatic triple negative breast cancer	93

A smart cauliflower-like carrier for astaxanthin delivery to relieve colon inflammation	93
Nanoparticle-mediated thermal Cancer therapies: Strategies to improve clinical translatability	92
Nanoghosts: Mesenchymal Stem cells derived nanoparticles as a unique approach for cartilage regeneration	91
Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice	91
Mechanism exploration of intestinal mucus penetration of nano-Se: regulated by polysaccharides with different functional groups and molecular weights	91
In vivo self-assembled small RNA targets H19 lncRNA for the treatment of colorectal cancer	90
Targosomes: Anti-HER2 PLGA nanocarriers for bioimaging, chemotherapy and local photothermal treatment of tumors and remote metastases	89
Spatiotemporally controlled Pseudomonas exotoxin transgene system combined with multifunctional nanoparticles for breast cancer antimetastatic therapy	89
Delivery of DNA octahedra enhanced by focused ultrasound with microbubbles for glioma therapy	89
Modified montmorillonite armed probiotics with enhanced on-site mucus-depleted intestinal colonization and H2S scavenging for colitis treatment	89
Development of a thermostable oxytocin microneedle patch	88
The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs	87