OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Controlled Release is 87. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-07-01 to 2025-07-01.)

Article	Citations
A PBPK model recapitulates early kinetics of anti-PEG antibody-mediated clearance of PEG-liposomes	411
Prediction of drug capturing by lipid emulsions in vivo for the treatment of a drug overdose	334
Outside Back Cover	312
Inside Back Cover	293
A self-assembled graphene oxide adjuvant induces both enhanced humoral and cellular immune responses in influenza vaccine	285
Intraperitoneal drug delivery systems for peritoneal carcinomatosis: Bridging the gap between research and clinical implementation	275
Nanoghosts: Mesenchymal Stem cells derived nanoparticles as a unique approach for cartilage regeneration	270
Oral mucosal vaccination using integrated fiber microneedles	261
Spatiotemporally controlled Pseudomonas exotoxin transgene system combined with multifunctional nanoparticles for breast cancer antimetastatic therapy	256
Single-cell RNA transcriptome landscape of murine liver following systemic administration of mesoporous silica nanoparticles	254
The colon targeting efficacies of mesalazine medications and their impacts on the gut microbiome	251
Topical formulation based on disease-specific nanoparticles for single-dose cure of psoriasis	226
Cavitation-assisted sonothrombolysis by asymmetrical nanostars for accelerated thrombolysis	217
Autophagy-modulating biomembrane nanostructures: A robust anticancer weapon by modulating the inner and outer cancer environment	211
Full-cycle study on developing a novel structured micromixer and evaluating the nanoparticle products as mRNA delivery carriers	200
Bioorthogonal conjugation and responsive nanocoating of probiotics for inflammatory bowel disease	199
Injectable nanocomposite hydrogel with cascade drug release for treatment of uveal melanoma	192
In-situ-formed immunotherapeutic and hemostatic dual drug-loaded nanohydrogel for preventing postoperative recurrence of hepatocellular carcinoma	183
Tagged extracellular vesicles with the RBD of the viral spike protein for delivery of antiviral agents against SARS-COV-2 infection	180
Hydrogel-forming microarray patches with solid dispersion reservoirs for transdermal long-acting microdepot delivery of a hydrophobic drug	178
Healing with precision: A multi-functional hydrogel-bioactive glass dressing boosts infected wound recovery and enhances neurogenesis in the wound bed	177
Nanoparticle-mediated thermal Cancer therapies: Strategies to improve clinical translatability	175
Adaptable peptide-based therapeutics modulating tumor microenvironment for combinatorial radio-immunotherapy	169
Inside Back Cover	167
Corrigendum to “Dissolving microarray patches loaded with a rotigotine nanosuspension: A potential alternative to Neupro® patch” [Journal of Controlled Release 372 (2024) 304–317]	165

Outside Back Cover	165
The inflammatory bowel disease and gut microbiome are restored by employing metformin-loaded alginate-shelled microcapsules	163
Transdermal carbon monoxide delivery	161
An efficient (nano) silica - In glucan particles protein encapsulation approach for improved thermal stability	153
Multifunctional nanoparticles potentiate in-situ tumor vaccines via reversing insufficient Photothermal therapy by disrupting tumor vasculature	150
Collagenase-modified polydopamine nanoparticles for safe and effective vitreolysis	149
The pharmacokinetic profile of mitomycin C released from an injectable supramolecular hydrogel in a rodent model	146
Oxygen-boosted fluorinated prodrug hybrid nanoassemblies for bidirectional amplification of breast cancer ferroptosis	143
Combinatorial physical methods for cellular therapy: Towards the future of cellular analysis?	140
Development of a thermostable oxytocin microneedle patch	139
Macrophage-targeting nano-formulated bicalutamide alleviates colitis by inducing MAP3K1-mediated degradation of NLRP3	133
Nano-trapping CXCL13 reduces regulatory B cells in tumor microenvironment and inhibits tumor growth	133
Outside Front Cover: Yisheng Peng et al	129
The osteogenic and angiogenic potential of microRNA-26a delivered via a non-viral delivery peptide for bone repair	127
Surface-engineered mesenchymal stem cell for refractory asthma therapy: Reversing airway remodeling	126
Enhanced browning of adipose tissue by mirabegron-microspheres	126
In vivo delivery of antioxidant enzymes with multi-functionalized lipid nanoparticles for sepsis therapy	126
Down-regulation of TNF-α via macrophage-targeted RNAi system for the treatment of acute inflammatory sepsis	125
Hypoxia-responsive oncolytic conjugate triggers type-II immunogenic cell death for enhanced photodynamic immunotherapy	125
Surface programmed bacteria as photo-controlled NO generator for tumor immunological and gas therapy	124
Dynamic versus static testing and in vivo mechanical performance of poly(glycolide-trimethylene carbonate-ε-caprolactone) delayed release implants	123
A next-generation STING agonist MSA-2: From mechanism to application	122
Outside Back Cover	122
Digging the intercellular crosstalk via extracellular vesicles: May exosomes be the drug delivery solution for target glioblastoma?	122
Hybrid nanopotentiators with dual cascade amplification for glioma combined interventional therapy	121
Nanotechnology-assisted intracellular delivery of antibody as a precision therapy approach for KRAS-driven tumors	118
Impact of interferon-γ on the target cell tropism of nanoparticles	118
Integrative approaches to enhance adeno-associated viral gene delivery	116
Autophagy-activating aluminum hydroxide nanovaccine for enhanced antigen presentation and anti-tumor immunity	115
Self-assembly hydrogels of therapeutic agents for local drug delivery	113
In vivo self-assembled small RNA targets H19 lncRNA for the treatment of colorectal cancer	110
Extracellular vesicles for renal therapeutics: State of the art and future perspective	108
Identification of functional biomarkers for personalized nanomedicine in advanced breast cancer in vitro models	108
Targosomes: Anti-HER2 PLGA nanocarriers for bioimaging, chemotherapy and local photothermal treatment of tumors and remote metastases	102
Nanomaterials applied in wound healing: Mechanisms, limitations and perspectives	102
The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs	102
Ferroptosis boosted oral cancer photodynamic therapy by carrier-free Sorafenib-Ce6 self-assembly nanoparticles	101
Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice	101
Laser-assisted nanocarrier delivery to achieve cutaneous siRNA targeting for attenuating psoriasiform dermatitis	100
An engineered dual function peptide to repair fractured bones	99
Conditioned media-integrated microneedles for hair regeneration through perifollicular angiogenesis	98
Modified montmorillonite armed probiotics with enhanced on-site mucus-depleted intestinal colonization and H2S scavenging for colitis treatment	98
Combination of multivalent DR5 receptor clustering agonists and histone deacetylase inhibitors for treatment of colon cancer	98
Enhancing gene transfection of poly(β-amino ester)s through modulation of amphiphilicity and chain sequence	96
Complement opsonization of nanoparticles: Differences between humans and preclinical species	95
ZIF-8-modified hydrogel sequentially delivers angiogenic and osteogenic growth factors to accelerate vascularized bone regeneration	95
Orthogonal upconversion nanocarriers for combined photodynamic therapy and precisely triggered gene silencing in combating keloids	94
Biomimetic reactive oxygen/nitrogen nanoscavengers inhibit “ferroptosis storm” and modulate immune targeting for acute kidney injury	94
Hybrid prodrug nanoassembly for hypoxia-triggered immunogenic chemotherapy and immune modulation	94
Alendronate-functionalized polymeric micelles target icaritin to bone for mitigating osteoporosis in a rat model	94

Mechanism exploration of intestinal mucus penetration of nano-Se: regulated by polysaccharides with different functional groups and molecular weights	93
Micellar paclitaxel boosts ICD and chemo-immunotherapy of metastatic triple negative breast cancer	92
Mechanisms of uptake and transport of particulate formulations in the small intestine	91
Delivery of DNA octahedra enhanced by focused ultrasound with microbubbles for glioma therapy	90
Tumor permeable self-delivery nanodrug targeting mitochondria for enhanced chemotherapy	90
White paper: Understanding, informing and defining the regulatory science of microneedle-based dosage forms that are applied to the skin	90
Advance cardiac nanomedicine by targeting the pathophysiological characteristics of heart failure	90
Unleashing the potential of cell biomimetic nanoparticles: Strategies and challenges in their design and fabrication for therapeutic applications	89
Functional nanoplatform for modulating cellular forces to enhance antitumor immunity via mechanotransduction	89
Dual-stimulus phototherapeutic nanogel for triggering pyroptosis to promote cancer immunotherapy	88
Accelerated blood clearance of PEGylated nanoparticles induced by PEG-based pharmaceutical excipients	88
Melittin-incorporated nanomedicines for enhanced cancer immunotherapy	87