Journal of Controlled Release

Papers
(The median citation count of Journal of Controlled Release is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Intradermal delivery of the antiretroviral drugs cabotegravir and rilpivirine by dissolving microarray patches: Investigation of lymphatic uptake679
Branched pegylated linker-auristatin to control hydrophobicity for the production of homogeneous minibody-drug conjugate against HER2-positive breast cancer516
Enhancing gene transfection of poly(β-amino ester)s through modulation of amphiphilicity and chain sequence388
Inside Back Cover354
Outside Back Cover337
Targeting antibodies dissociate from drug delivery liposomes during blood circulation303
Smart theranostic contact lenses256
Recombinant collagen microneedles for transdermal delivery of antibacterial copper-DNA nanoparticles to treat skin and soft tissue infections246
Dual-responsive stem cell microspheres modified with BDNF for enhanced neural repair in diabetic erectile dysfunction243
Unveiling the drug delivery mechanism of graphene oxide dots at the atomic scale238
Design, evaluation, and in vitro–in vivo correlation of self-nanoemulsifying drug delivery systems to improve the oral absorption of exenatide235
Functional nanoplatform for modulating cellular forces to enhance antitumor immunity via mechanotransduction230
Knocking down of Xkr8 enhances chemotherapy efficacy through modulating tumor immune microenvironment229
Enhancing calvarial defects repair with PDGF-BB mimetic peptide hydrogels229
Targeted delivery of polymeric NO-donor micelles to hepatic stellate cells for restoration of liver function and inhibition of hepatic fibrosis224
Disclosing long-term tolerance, efficacy and penetration properties of hyaluronic acid-coated latanoprost-loaded liposomes as chronic glaucoma therapy212
Gas-propelled anti-hair follicle aging microneedle patch for the treatment of androgenetic alopecia199
Core-shell vector-mediated co-delivery of CRISPR/Cas9 system and hydrophobic drugs against triple-negative breast cancer stem cells191
Hybrid prodrug nanoassembly for hypoxia-triggered immunogenic chemotherapy and immune modulation188
Orthogonal upconversion nanocarriers for combined photodynamic therapy and precisely triggered gene silencing in combating keloids172
Recent nanoengineered diagnostic and therapeutic advancements in management of Sepsis171
An antibacterial, multifunctional nanogel for efficient treatment of neutrophilic asthma171
Intraperitoneal drug delivery systems for peritoneal carcinomatosis: Bridging the gap between research and clinical implementation161
Fatty acid conjugated EPI-X4 derivatives with increased activity and in vivo stability160
Injectable dual thermoreversible hydrogel for sustained intramuscular drug delivery158
Dissolving microarray patches loaded with a rotigotine nanosuspension: A potential alternative to Neupro® patch156
Controlled bioorthogonal activation of Bromodomain-containing protein 4 degrader by co-delivery of PROTAC and Pd-catalyst for tumor-specific therapy154
Pickering emulsion-guided monomeric delivery of monophosphoryl lipid A for enhanced vaccination153
Engineered bacterial membrane vesicle as safe and efficient nano-heaters to reprogram tumor microenvironment for enhanced immunotherapy148
Biocompatible polymer-based micro/nanorobots for theranostic translational applications148
Systemically targeting monocytic myeloid-derived suppressor cells using dendrimers and their cell-level biodistribution kinetics145
ZIF-8-modified hydrogel sequentially delivers angiogenic and osteogenic growth factors to accelerate vascularized bone regeneration143
Novel lipid nanovesicle-loaded dissolving microarray patches for fenretinide in breast cancer chemoprevention140
Modified montmorillonite armed probiotics with enhanced on-site mucus-depleted intestinal colonization and H2S scavenging for colitis treatment138
Corrigendum to “Dissolving microarray patches loaded with a rotigotine nanosuspension: A potential alternative to Neupro® patch” [Journal of Controlled Release 372 (2024) 304–317]137
Outside Back Cover135
Publisher's note135
Outside Front Cover127
Engineered peptide-drug conjugate provides sustained protection of retinal ganglion cells with topical administration in rats126
Prediction of drug capturing by lipid emulsions in vivo for the treatment of a drug overdose125
Outside Back Cover123
Content list including Graphcal Abstracts123
Outside Back Cover122
Letter to the editor regarding “Translation of focused ultrasound for blood-brain barrier opening in glioma”120
Inside Back Cover120
Mechanisms of cellular retention of melanin bound drugs: Experiments and computational modeling116
Surgical management of peritoneal metastasis: Opportunities for pharmaceutical research115
A tribute to my biosimilar114
Protein corona-driven nanovaccines improve antigen intracellular release and immunotherapy efficacy114
Inside Front Cover112
Editorial Board112
Contents list including Graphcal Abstracts112
Editorial Board111
An injectable carrier for spatiotemporal and sequential release of therapeutic substances to treat myocardial infarction111
Antigen-specific T cell activation through targeted delivery of in-situ generated antigen and calcium ionophore to enhance antitumor immunotherapy109
Inside Front Cover108
Dynamic immuno-nanomedicines in oncology108
Outside Back Cover107
Control of cell penetration enhancer shielding and endosomal escape-kinetics crucial for efficient and biocompatible siRNA delivery107
A self-assembled graphene oxide adjuvant induces both enhanced humoral and cellular immune responses in influenza vaccine104
Content list including Graphcal Abstracts100
Outside Front Cover100
The pharmacokinetics of PEGylated liposomal doxorubicin are not significantly affected by sex in rats or humans, but may be affected by immune dysfunction98
Outside Front Cover97
Inside Back Cover97
Inside Front Cover97
Outside Back Cover95
Outside Front Cover95
Inside Back Cover95
Inside Front Cover94
Inside Back Cover92
Editorial Board91
Inside Back Cover89
Editorial Board88
Content list including Graphcal Abstracts88
Content list including Graphcal Abstracts87
Inside Front Cover87
Outside Back Cover86
Outside Back Cover86
Editorial Board86
Outside Back Cover84
Targeting therapy for prostate cancer by pharmaceutical and clinical pharmaceutical strategies84
Inside Back Cover84
Tumor permeable self-delivery nanodrug targeting mitochondria for enhanced chemotherapy83
Redox modulation with a perfluorocarbon nanoparticle to reverse Treg-mediated immunosuppression and enhance anti-tumor immunity83
“Click” amphotericin B in prodrug nanoformulations for enhanced systemic fungemia treatment83
Employing single valency polyphenol to prepare metal-phenolic network antitumor reagents through FeOOH assistance82
Self-targeted polymersomal co-formulation of doxorubicin, camptothecin and FOXM1 aptamer for efficient treatment of non-small cell lung cancer81
Emerging nanotechnological approaches to regulating tumor vasculature for cancer therapy81
Dual-stimulus phototherapeutic nanogel for triggering pyroptosis to promote cancer immunotherapy79
Targeting glycolysis for cancer therapy using drug delivery systems79
A PBPK model recapitulates early kinetics of anti-PEG antibody-mediated clearance of PEG-liposomes79
Shape-directed drug release and transport of erythrocyte-like nanodisks augment chemotherapy78
Bioorthogonal conjugation and responsive nanocoating of probiotics for inflammatory bowel disease78
Metal complex-based liposomes: Applications and prospects in cancer diagnostics and therapeutics77
NIR-triggered ligand-presenting nanocarriers for enhancing synergistic photothermal-chemotherapy77
PET imaging to assess the impact of P-glycoprotein on pulmonary drug delivery in rats76
Affibody-mediated controlled release of fibroblast growth factor 276
Translation of focused ultrasound for blood-brain barrier opening in glioma76
Physicochemical and structural insights into lyophilized mRNA-LNP from lyoprotectant and buffer screenings75
Glioma diagnosis and therapy: Current challenges and nanomaterial-based solutions75
Retraction notice to “In vitro and in vivo evaluation of degradation, toxicity, biodistribution, and clearance of silica nanoparticles as a function of size, porosity, density, and composition” [Journ75
Engineered manganese-BODIPY coordinated nanoadjuvants for enhanced NIR-II photo-metalloimmunotherapy75
Nebulization of extracellular vesicles: A promising small RNA delivery approach for lung diseases75
Lipid nanoparticles to silence androgen receptor variants for prostate cancer therapy74
Magnetic resonance imaging of pancreatic islets using tissue–adhesive particles containing iron oxide nanoparticles74
Cancer immunotherapy from biology to nanomedicine74
Porous scaffold for mesenchymal cell encapsulation and exosome-based therapy of ischemic diseases73
Differentiated mesenchymal stem cells-derived exosomes immobilized in decellularized sciatic nerve hydrogels for peripheral nerve repair73
Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma73
Brain-targeted CRISPR/Cas9 nanomedicine for effective glioblastoma therapy73
Dual mechanistic TRAIL nanocarrier based on PEGylated heparin taurocholate and protamine which exerts both pro-apoptotic and anti-angiogenic effects73
Delivery of mRNA for regulating functions of immune cells72
Thermoresponsive polymeric dexamethasone prodrug for arthritis pain72
Tanshinone IIA enhances the therapeutic efficacy of mesenchymal stem cells derived exosomes in myocardial ischemia/reperfusion injury via up-regulating miR-223-5p72
Glucose-responsive insulin microneedle patches for long-acting delivery and release visualization72
Research progress of microneedles in the treatment of melanoma71
Small EV-based delivery of CpG ODNs for melanoma postsurgical immunotherapy70
Self-assembly hydrogels of therapeutic agents for local drug delivery70
Spatiotemporal controlled released hydrogels for multi-system regulated bone regeneration69
Transdermal delivery of Fn14 siRNA using a novel composite ionic liquid for treatment of psoriasis-like skin lesions69
Fluoride releasing photothermal responsive TiO2 matrices for antibiosis, biosealing and bone regeneration69
Healing with precision: A multi-functional hydrogel-bioactive glass dressing boosts infected wound recovery and enhances neurogenesis in the wound bed69
Enhancing preventive and therapeutic cancer vaccine efficacy through biotherapeutic ligand-associated extracellular vesicles68
Ultrasound-activated microbubbles mediate F-actin disruptions and endothelial gap formation during sonoporation68
Hybrid nanopotentiators with dual cascade amplification for glioma combined interventional therapy68
Combination of multivalent DR5 receptor clustering agonists and histone deacetylase inhibitors for treatment of colon cancer67
Hollow microneedles for ocular drug delivery66
Efficient ultrasound-mediated drug delivery to orthotopic liver tumors – Direct comparison of doxorubicin-loaded nanobubbles and microbubbles66
Rational design of a poly-L-glutamic acid-based combination conjugate for hormone-responsive breast cancer treatment66
Extracellular vesicles for renal therapeutics: State of the art and future perspective65
Recent advances in drug delivery and targeting to the brain65
A therapeutic DC vaccine with maintained immunological activity exhibits robust anti-tumor efficacy65
Wearable nitric oxide-releasing antibacterial insert for preventing device-associated infections65
TRAIL & EGFR affibody dual-display on a protein nanoparticle synergistically suppresses tumor growth65
Laser-assisted nanocarrier delivery to achieve cutaneous siRNA targeting for attenuating psoriasiform dermatitis65
Piperine loaded metal organic frameworks reverse doxorubicin induced chemobrain in adult zebrafish65
Overcoming drug resistance with a docetaxel and disulfiram loaded pH-sensitive nanoparticle64
Intravitreal CendR peptides target laser-induced choroidal neovascularization sites in mice63
3D printed PLGA implants: APF DDM vs. FDM63
Liposomal encapsulation of trans-crocetin enhances oxygenation in patients with COVID-19-related ARDS receiving mechanical ventilation63
Inside Front Cover63
Metabolic reprogramming of macrophages by a nano-sized opsonization strategy to restore M1/M2 balance for osteoarthritis therapy63
Inside Back Cover63
Enhanced browning of adipose tissue by mirabegron-microspheres63
Outside Back Cover63
Role of circular RNA and its delivery strategies to cancer – An overview63
Spatiotemporally controlled Pseudomonas exotoxin transgene system combined with multifunctional nanoparticles for breast cancer antimetastatic therapy63
Noninvasive ultrasonic induction of cerebrospinal fluid flow enhances intrathecal drug delivery62
Inside Front Cover62
A Mn Al double adjuvant nanovaccine to induce strong humoral and cellular immune responses62
Comprehensive analysis of the influence of physicochemical properties and tumor-associated environments on liposome intratumoral penetration62
Mucoadhesive film for oral delivery of vaccines for protection of the respiratory tract62
Engineered liposomes targeting hepatic stellate cells overcome pathological barriers and reverse liver fibrosis61
Pore engineering of micro/mesoporous nanomaterials for encapsulation, controlled release and variegated applications of essential oils61
Evaluation of linear versus star-like polymer anti-cancer nanomedicines in mouse models61
Purification processes of polymeric nanoparticles: How to improve their clinical translation?61
Gadolinium-labeled affibody-XTEN recombinant vector for detection of HER2+ lesions of ovarian cancer lung metastasis using quantitative MRI61
Studying the stability of polymer nanoparticles by size exclusion chromatography of radioactive polymers61
Nonalcoholic fatty liver disease: Current therapies and future perspectives in drug delivery61
Controlling release from encapsulated drug-loaded devices: insights from modeling the dissolution front propagation60
Bio-inspired engineered ferritin-albumin nanocomplexes for targeted ferroptosis therapy60
Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice60
Surface programmed bacteria as photo-controlled NO generator for tumor immunological and gas therapy60
Self-activated arsenic manganite nanohybrids for visible and synergistic thermo/immuno-arsenotherapy60
Enhancing pulmonary delivery and immunomodulation of respiratory diseases through virus-mimicking nanoparticles59
Poly(phenylalanine) and poly(3,4-dihydroxy-L-phenylalanine): Promising biomedical materials for building stimuli-responsive nanocarriers59
Outside Front Cover59
Content list including Graphcal Abstracts59
Outside Back Cover: Anqi Ye et al59
Corrigendum to ‘Quercetin-loaded freeze-dried nanomicelles: Improving absorption and anti-glioma efficiency in vitro and in vivo.’ [G. Wang et al. / Journal of Controlled Release 235 (2016) 276–290.]59
Integrating targeting and drug retention: A promising approach for cancer treatment58
Lipid nanoparticles and transcranial focused ultrasound enhance the delivery of SOD1 antisense oligonucleotides to the murine brain for ALS therapy58
Encapsulation of individual mammalian cells as a cell-based drug delivery carrier for lung cancer treatment58
The inflammatory bowel disease and gut microbiome are restored by employing metformin-loaded alginate-shelled microcapsules57
Delivery of FBXO6 with highly branched poly(β-amino ester)s to modulate the inflammatory environment for the treatment of osteoarthritis57
White paper: Understanding, informing and defining the regulatory science of microneedle-based dosage forms that are applied to the skin56
Delivery of self-replicating messenger RNA into the brain for the treatment of ischemic stroke56
Intelligent sequential degradation hydrogels by releasing bimetal-phenolic for enhanced diabetic wound healing56
DMPC/Chol liposomal copper CX5461 is therapeutically superior to a DSPC/Chol formulation56
A mannosylated polymer with endosomal release properties for peptide antigen delivery55
In vivo self-assembled small RNA targets H19 lncRNA for the treatment of colorectal cancer55
Multicyclic topology-enhanced anticancer drug delivery55
Investigating the delivery of PD-L1-targeted immunoliposomes in a dynamic cervical cancer-on-a-chip model54
Ultrasound-triggered topical oxygen delivery enhances synergistic sonodynamic and antibody therapies against hypoxic gastric cancer54
Corrigendum to “Enhanced antitumor and anti-metastasis efficiency via combined treatment with CXCR4 antagonist and liposomal doxorubicin” [Journal of Controlled Release, Volume 196 (2014), Pages 324–354
Macrophage-targeting nano-formulated bicalutamide alleviates colitis by inducing MAP3K1-mediated degradation of NLRP354
Dynamic versus static testing and in vivo mechanical performance of poly(glycolide-trimethylene carbonate-ε-caprolactone) delayed release implants54
Outside Front Cover: Yisheng Peng et al54
3D mesenchymal stem cell exosome-functionalized hydrogels for corneal wound healing54
Tumor-stromal opening via S. typhimurium VNP20009 administration for complete inhibition of refractory tumor growth with liposomal anticancer drugs54
Multidrug micelles and sonopermeation for chemotherapy co-delivery to brain tumors54
Microneedle-based nanodrugs for tumor immunotherapy54
Archaea-inspired deoxyribonuclease I liposomes prevent multiple organ dysfunction in sepsis54
Oxygen-supplying nanotherapeutics for bacterial septic arthritis via hypoxia-relief-enhanced antimicrobial and anti-inflammatory phototherapy53
Microneedle-based cell delivery and cell sampling for biomedical applications53
Cationic amino-acid functionalized polymethacrylamide vectors for siRNA transfection based on modification of poly(2-isopropenyl-2-oxazoline)53
Bioactive hydrogel formulations for regeneration of pathological bone defects53
Mesoporous zinc oxide-based drug delivery system offers an antifungal and immunoregulatory strategy for treating keratitis53
Triggered release from thermosensitive liposomes improves tumor targeting of vinorelbine53
Full-cycle study on developing a novel structured micromixer and evaluating the nanoparticle products as mRNA delivery carriers53
Phage-liposome nanoconjugates for orthopedic biofilm eradication53
Melittin-incorporated nanomedicines for enhanced cancer immunotherapy53
Photoresponsive polymeric microneedles: An innovative way to monitor and treat diseases53
Self-healing adhesive hydrogels for sustained ozone release: Enhanced antibacterial properties and improved wound healing52
Targeting diffuse midline gliomas: The promise of focused ultrasound-mediated blood-brain barrier opening52
Nanoparticulate drug combination inhibits DNA damage repair and PD-L1 expression in BRCA-mutant and wild type triple-negative breast cancer52
Physical and chemical advances of synthetic delivery vehicles to enhance mRNA vaccine efficacy52
Oral delivery of stem-cell-loaded hydrogel microcapsules restores gut inflammation and microbiota52
Corrigendum to “Gold core@CeO2 halfshell Janus nanocomposites catalyze targeted sulfate radical for periodontitis therapy” [Journal of Controlled Release 370 (2024) 600–613]52
PEG2000-PLA-based nanoscale polymeric micelles reduce paclitaxel-related toxicity in beagle dogs52
Oxygen-boosted fluorinated prodrug hybrid nanoassemblies for bidirectional amplification of breast cancer ferroptosis51
Cyclosporine-loaded micelles for ocular delivery: Investigating the penetration mechanisms51
Autophagy-activating aluminum hydroxide nanovaccine for enhanced antigen presentation and anti-tumor immunity51
Recent advances in lipid-engineered multifunctional nanophytomedicines for cancer targeting51
Regulation of mechanical properties of microcapsules and their applications50
Biomaterials to regulate tumor extracellular matrix in immunotherapy50
Controlled extracellular vesicles release from aminoguanidine nanoparticle-loaded polylysine hydrogel for synergistic treatment of spinal cord injury50
Fluorogenic RNA-based biomaterials for imaging and tracking the cargo of extracellular vesicles50
cRGD enables rapid phagocytosis of liposomal vancomycin for intracellular bacterial clearance50
Polycation fluorination improves intraperitoneal siRNA delivery in metastatic pancreatic cancer50
Spleen-targeted delivery systems and strategies for spleen-related diseases50
Enhanced BBB and BBTB penetration and improved anti-glioma behavior of Bortezomib through dual-targeting nanostructured lipid carriers50
Perspective on drug delivery in 205049
Injectable immunogel based on polymerized phenylboronic acid and mannan for cancer immunotherapy49
Inhalation delivery of repurposed drugs for lung cancer: Approaches, benefits and challenges49
Targeting bone microenvironments for treatment and early detection of cancer bone metastatic niches49
Current trends in smart mesoporous silica-based nanovehicles for photoactivated cancer therapy49
On-demand release of the small-molecule TrkB agonist improves neuron-Schwann cell interactions49
Smart combination of aluminum hydroxide and MF59 to induce strong cellular immune responses49
Tailoring carrier-free nanocombo of small-molecule prodrug for combinational cancer therapy49
Targeted delivery via albumin corona nanocomplex to renal tubules to alleviate acute kidney injury48
The colon targeting efficacies of mesalazine medications and their impacts on the gut microbiome48
Shear force-ROS sequential responsive drug delivery system for improving cerebral thrombosis microcirculation and neurological function48
Aptamer-based therapy for fighting biofilm-associated infections48
Nanocracker capable of simultaneously reversing both P-glycoprotein and tumor microenvironment48
Electromechanical convective drug delivery devices for overcoming diffusion barriers48
Recyclable cell-surface chemical tags for repetitive cancer targeting48
Supramolecular gel with enhanced immunomodulatory effects presents a minimally invasive treatment strategy for eosinophilic chronic rhinosinusitis48
AI-directed formulation strategy design initiates rational drug development48
Not only in silico drug discovery: Molecular modeling towards in silico drug delivery formulations48
Hyperthermia-induced doxorubicin delivery from thermosensitive liposomes via MR-HIFU in a pig model48
Matrix metalloproteinase-1 decorated polymersomes, a surface-active extracellular matrix therapeutic, potentiates collagen degradation and attenuates early liver fibrosis48
Local drug delivery challenges and innovations in spinal neurosurgery48
Outside Back Cover47
Drug-free tumor therapy via spermine-responsive intracellular biomineralization47
Multiple CEST contrast imaging of nose-to-brain drug delivery using iohexol liposomes at 3T MRI47
Inflammation-responsive molecular-gated contact lens for the treatment of corneal neovascularization47
Cavitation monitoring, treatment strategy, and acoustic simulations of focused ultrasound blood-brain barrier disruption in patients with glioblastoma47
Charge balanced aggregation: A universal approach to aqueous organic nanocrystals47
0.11480689048767