Trends in Genetics

Article	Citations
Advisory Board and Contents	766
Crossover recombination between homologous chromosomes in meiosis: recent progress and remaining mysteries	664
Advisory Board and Contents	295
Omics studies of DNA G-/C-quadruplexes in plants	230
Epigenetic networks driving T cell identity and plasticity during immunosenescence	224
Carcinoscorpius rotundicauda (mangrove horseshoe crab)	205
Subscription and Copyright Information	192
Advisory Board and Contents	162
Genetic buffering mechanisms in SNF2-family translocases	141
Assessing autosomal aneuploidy in ancient genomes	132
Heritable epigenetic changes at single genes: challenges and opportunities in Caenorhabditis elegans	123
Pursuing totipotency: authentic totipotent stem cells in culture	119
Emerging regulatory mechanisms of noncoding RNAs in topologically associating domains	117
The sound of silence: mechanisms and implications of HUSH complex function	109
PCNA cycling dynamics during DNA replication and repair in mammals	104
The complex universe of inactive PARP1	96
Intron retention: importance, challenges, and opportunities	93
Advisory Board and Contents	92
A new hypothesis to explain disease dominance	87
A three-dimensional genomics view for speciation research	83
The chromatin roots of abnormal splicing in autism	82
Multi-omic genetic scores advance disease research	77
Immunity and lifespan: answering long-standing questions with comparative genomics	75
Histone lactylation: epigenetic mark of glycolytic switch	72
m6A in the coding sequence: linking deposition, translation, and decay	71

Genome structural variation in human evolution	70
The molecular evolutionary basis of species formation revisited	69
Evolution of piRNA-guided defense against transposable elements	66
Clonal ants reveal a potentially hidden meiotic feature	63
Canis familiaris (Great Dane domestic dog)	62
Subscription and Copyright Information	62
Advisory Board and Contents	61
Advisory Board and Contents	60
Advisory Board and Contents	59
Animal origins: looping back in time	59
Toward DNA-based taxonomy of prokaryotes and microeukaryotes	58
The making and breaking of tRNAs by ribonucleases	58
Ionizing radiation damage and repair from 3D-genomic perspective	56
Dynamics of the Streptomyces chromosome: chance and necessity	55
From genetic associations to genes: methods, applications, and challenges	54
Features and biomedical relevance of circular RNA biogenesis	51
Cis to trans: small ORF functions emerging through evolution	51
Insights into Spt6: a histone chaperone that functions in transcription, DNA replication, and genome stability	50
Progress and opportunities through use of genomics in animal production	49
Finding functional microproteins	47
Revealing microRNA regulation in single cells	46
DNA base editing in nuclear and organellar genomes	46
Pioneer factors: roles and their regulation in development	45
Advisory Board and Contents	44
Subscription and Copyright Information	43
Subscription and Copyright Information	42
Subscription and Copyright Information	42
Does TFIIH move nucleosomes?	41
Unraveling the diversity and cultural heritage of fruit crops through paleogenomics	40
Extracellular vesicles as modifiers of epigenomic profiles	39
In silico genome transplants and the cis-regulatory basis of biodiversity	38
The illusion of clarity in familiar genetics diagrams	37
Leveraging microbiome information for animal genetic improvement	37
Exploring the world of small proteins in plant biology and bioengineering	37
Wheat genomics: genomes, pangenomes, and beyond	37
Genetic architecture of brain morphology and overlap with neuropsychiatric traits	37
Protist genomics: key to understanding eukaryotic evolution	37
Advisory Board and Contents	36
Advisory Board and Contents	36
Earth Biogenome Project: present status and future plans	35
There is another: H3K27me3-mediated genomic imprinting	35
Open practices in our science and our courtrooms	35
Singling out motor neurons in the age of single-cell transcriptomics	35
Mendel elucidated: Big Science comes to the humble garden pea	35
Directing RNA-modifying machineries towards endogenous RNAs: opportunities and challenges	34
Dissecting super-enhancer heterogeneity: time to re-examine cancer subtypes?	34
mRNA-binding proteins and cell cycle progression	33
Evolutionary impact of chimeric RNAs on generating phenotypic plasticity in human cells	33
Positive-strand RNA virus genome replication organelles: structure, assembly, control	32
Mapping cellular responses to DNA double-strand breaks using CRISPR technologies	32

The origins and evolution of translation factors	32
The H2A.Z-nucleosome code in mammals: emerging functions	31
Clocks at sea: the genome-editing tide is rising	31
Rare variants and handedness: spotlight on TUBB4B	31
Architectural RNAs: blueprints for functional membraneless organelle assembly	30
Clonal selection parallels between normal and cancer tissues	30
Subscription and Copyright Information	30
Sleeping less with a SIK3 mutation	30
Cocos nucifera (coconut)	30
Dosage compensation in non-model insects – progress and perspectives	29
Evolving a favorable distribution for mutation effects	29
Chromoanagenesis in plants: triggers, mechanisms, and potential impact	28
Beyond sequencing: machine learning algorithms extract biology hidden in Nanopore signal data	28
Complex genomic rearrangements: an underestimated cause of rare diseases	28
Molecular circuits for genomic recording of cellular events	28
Genetics of human handedness: microtubules and beyond	27
The influence of transposable elements on animal colouration	26
Mitochondrial-derived microproteins: from discovery to function	26
Convergent evolution for antibiotic biosynthesis in bacteria and animals	26
Complexities of mammalian transcriptome revealed by targeted RNA enrichment techniques	25
Is it time to reassess variant annotation?	25
Subscription and Copyright Information	25
Long-read transcriptome sequencing reveals allele-specific variants at high resolution	25
The rare-to-common disease journey: a winding road to new therapies	24
Pathway-level convergence: an underexplored aspect of convergent evolution	24
Emerging insights into the genetics and evolution of human same-sex sexual behavior	24
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A new Down syndrome rat model races forward	23
The versatile relationships between eIF4E and eIF4E-interacting proteins	23
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Advisory Board and Contents	23
Subscription and Copyright Information	23
Repetitive elements in aging and neurodegeneration	22
Into the multiverse: advances in single-cell multiomic profiling	22
Predicting genome organisation and function with mechanistic modelling	22
Complex diseases meet deep phenotyping and generative AI	22
Integration of DNA damage responses with dynamic spatial genome organization	22
Current concepts, advances, and challenges in deciphering the human microbiota with metatranscriptomics	20
The impact of IDR phosphorylation on the RNA binding profiles of proteins	20
In search of a cure: PACS1 Research Foundation as a model of rare disease therapy development	20
Genomic newborn screening: exploring opportunities and navigating pitfalls while ensuring inclusivity	19
Bear essentials	19
The essential but enigmatic regulatory role of HERVH in pluripotency	19
The ribosome’s comeback: new role in body weight regulation	19
Are phenome-wide association studies feasible in a developing country?	19
Across the North Sea and beyond	19
DNA lesions piece together impossible trees	18
Dynamics of replication timing during mammalian development	18
Zebrafish and idiopathic scoliosis: the ‘unknown knowns’	18
Subscription and Copyright Information	18
Advisory Board and Contents	18
Noncanonical DNA structures are drivers of genome evolution	17
Mitochondria and G-quadruplex evolution: an intertwined relationship	17
Genome stability from the perspective of telomere length	17
Computational methods for allele-specific expression in single cells	17
DNA methylation: a historical perspective	17
Cross-kingdom RNA communication in plant–bacterial interaction	17
Mendelian randomization analyses for PCOS: evidence, opportunities, and challenges	17
Maturation and application of phenome-wide association studies	16
Modeling the origin of cells	16
Honeybees’ novel complementary sex-determining system: function and origin	16
Advisory Board and Contents	16
Emerging functions of mitochondria-encoded noncoding RNAs	16
Optimizing homology-directed repair for gene editing: the potential of single-stranded DNA donors	16
Approaches and challenges in genome-wide circular RNA identification and quantification	16
Chromatin accessibility provides a window into the genetic etiology of human brain disease	15
Subscription and Copyright Information	15
AlphaGenome: a Swiss-army knife for exploring non-coding DNA	15
Insights from multi-omics integration in complex disease primary tissues	15
Mitochondrial-derived microproteins: from discovery to function	15
The wild side of grape genomics	15
Whole-genome doubling in tissues and tumors	15
Opportunities and tradeoffs in single-cell transcriptomic technologies	15
The searchable chromosome	15
Beyond the gene: decoding alternative isoforms	15
Advisory Board and Contents	14
Subscription and Copyright Information	14
Advisory Board and Contents	14

Advancing evolutionary medicine with complete primate genomes and advanced biotechnologies	14
Advisory Board and Contents	14
Subscription and Copyright Information	14
Yes, polygenic sex determination is a thing!	13
Breakage in breakage–fusion–bridge cycle: an 80-year-old mystery	13
Genetic adaptations for the oceanic success of fish eggs	13
Finding genes and pathways that underlie coral adaptation	12
Spatial omics enters the microscopic realm: opportunities and challenges	12
Advisory Board and Contents	12
Noncoding snoRNA host genes are a distinct subclass of long noncoding RNAs	12
iPSC-derived organ-on-a-chip models for personalized human genetics and pharmacogenomics studies	12
Every gene can (and possibly will) be associated with cancer	12
Intragenomic mutational heterogeneity: structural and functional insights from gene evolution	12
ATRX, a guardian of chromatin	12
ReNU syndrome – a newly discovered prevalent neurodevelopmental disorder	12
Subscription and Copyright Information	12
Advances in methods for tRNA sequencing and quantification	11
Genetic and epigenetic defects of the RNA modification machinery in cancer	11
Interplay between regulatory elements and chromatin topology in cellular lineage determination	11
Cis-regulatory dynamics in plant domestication	11
Selective REcruitmeNt of plant DNA polymerases by geminivirus	11
Epigenetic perspectives on wheat speciation, adaptation, and development	11
Selective Xi reactivation and alternative methods to restore MECP2 function in Rett syndrome	11
Aneuploidy in human cancer: new tools and perspectives	11
Starships: a new frontier for fungal biology	11
Interruptions impact clinical features of repeat expansion diseases, but how are they gained and lost?	11
New insights into oocyte cytoplasmic lattice-associated proteins	11
Chromatin-centric insights into DNA replication	11
A multi-epigenomic map of endurance exercise training	11
An updated view of the kinetochore architecture	11
miRNA biogenesis and inherited disorders: clinico-molecular insights	10
People with disability and privacy in precision medicine research: what’s at stake?	10
Recent insights into eukaryotic double-strand DNA break repair unveiled by single-molecule methods	10
Transposon–host arms race: a saga of genome evolution	10
ADAR1 and its implications in cancer development and treatment	10
Contributions of epigenomic and epitranscriptomic methylation to animal colouration	10
Chromosome-scale haplotype-resolved pangenomics	10
Take a walk on the KRAB side	10
Advisory Board and Contents	10
Subscription and Copyright Information	10
Fun-sized and fundamental	10
A blood drop through the pore: nanopore sequencing in hematology	10
Molecular animations in genomics education: designing for whom?	9
Subscription and Copyright Information	9
Advisory Board and Contents	9
Patient privacy in AI-driven omics methods	9
FIRRM and FIGNL1: partners in the regulation of homologous recombination	9
Leveraging spatial multiomics to unravel tissue architecture in embryo development	9
Subscription and Copyright Information	9
Genetic disorders of cellular trafficking	9
Gene-dosage issues: a recurrent theme in whole genome duplication events	9
The impact of human accelerated regions on neuronal development	9
Emerging links between phase separation and transcription factor haploinsufficiency	9
Haldane’s duel: intragenomic conflict, selfish Y chromosomes and speciation	9
Unraveling brain complexity: from single-cell to spatial m6A technologies	8
Preventing excess replication origin activation to ensure genome stability	8
Duplicated gene networks promote ‘hopeful’ phenotypic variation	8
Functional characterization of human genomic variation linked to polygenic diseases	8
Out of the dark: the emerging roles of lncRNAs in pain	8
The evolution of the GALactose utilization pathway in budding yeasts	8
A dive into the unknome	7
Genetic and epigenetic landscape of male infertility	7
Achieve your research goals: a project management toolkit for graduate studies	7
Advisory Board and Contents	7
RNAPII driven post-translational modifications of nucleosomal histones	7
Subscription and Copyright Information	7
The impact of human accelerated regions on neuronal development	7
Bridging biological cfDNA features and machine learning approaches	7
Advisory Board and Contents	7
Single-cell omics sequencing technologies: the long-read generation	7
Retrotransposon renaissance in early embryos	7
DEAD/DEAH-box RNA helicases shape the risk of neurodevelopmental disorders	7
Time is ticking faster for long genes in aging	7
From darkness to discovery: evolutionary, adaptive, and translational genetic insights from cavefish	7
Epigenetic control of muscle stem cells: time for a new dimension	7
Picochlorum sp. SENEW3	7
Exploring the role of phage plasmids in gene transfers	6
Aegilops tauschii presents a genetic roadmap for hexaploid wheat improvement	6
The evolution of aging and lifespan	6
We must not ignore eugenics in our genetics curriculum	6
Advisory Board and Contents	6
Strategies for dissecting the complexity of neurodevelopmental disorders	6
Therapeutic and prognostic insights from the analysis of cancer mutational signatures	6
Single-cell dissection of tumor microenvironmental response and resistance to cancer therapy	6
Subscription and Copyright Information	6
Supergenes promote ecological stasis in a keystone species	6
The very early evolution of biological complexity	6
New mechanism of chromatin compartmentalization by BRD2	6
The multifaceted effects of YTHDC1-mediated nuclear m6A recognition	6
Structure-specific nucleases: role in Okazaki fragment maturation	6
Gene reporters for magnetic resonance imaging	6
Alternative paths for genetics, then and now: Q&A with Gregory Radick about Disputed Inheritance	6
Homologous recombination counteracts mismatch repair to promote fertility and genetic diversity	6
Gene product diversity: adaptive or not?	5
Conditional mutagenesis strategies in zebrafish	5