Trends in Genetics

Article	Citations
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Complexities of mammalian transcriptome revealed by targeted RNA enrichment techniques	518
Emerging insights into the genetics and evolution of human same-sex sexual behavior	429
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Omics studies of DNA G-/C-quadruplexes in plants	176
DEAD/DEAH-box RNA helicases shape the risk of neurodevelopmental disorders	164
Genetic buffering mechanisms in SNF2-family translocases	162
The ABCs of the H2Bs: The histone H2B sequences, variants, and modifications	150
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Tropical trees inherit low-frequency somatic mutations	134
Advisory Board and Contents	132
Unraveling aging from transcriptomics	131
Advances in euglenoid genomics: unravelling the fascinating biology of a complex clade	110
Driving to Safety: CRISPR-Based Genetic Approaches to Reducing Antibiotic Resistance	108
Emerging functions of circular RNA in aging	106
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Advisory Board and Contents	97
Advisory Board and Contents	95
Linker H1 is an ‘epi’centre of plant defence	94
Haldane’s duel: intragenomic conflict, selfish Y chromosomes and speciation	94
Advisory Board and Contents	91
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Hitting the brakes on transcription to extend lifespan	73
Advisory Board and Contents	72

Advisory Board and Contents	70
Advisory Board and Contents	69
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Advisory Board and Contents	66
Discovering genes that affect cognitive ability	64
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Advisory Board and Contents	63
The African Society of Human Genetics successfully launches global data science workshops	62
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Carcinoscorpius rotundicauda (mangrove horseshoe crab)	56
Molecular animations in genomics education: designing for whom?	55
Consequences of trisomy syndromes – 21 and beyond	54
Duplicated gene networks promote ‘hopeful’ phenotypic variation	54
Repetitive elements in aging and neurodegeneration	51
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Microproteins in cancer: identification, biological functions, and clinical implications	50
In search of a cure: PACS1 Research Foundation as a model of rare disease therapy development	47
The impact of IDR phosphorylation on the RNA binding profiles of proteins	46
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Amyloids transmit acquired epigenetic feminizing information between generations	45
Unpacking chromatin remodelling in germ cells: implications for development and evolution	45
Advisory Board and Contents	44
Assessing autosomal aneuploidy in ancient genomes	44
Patient privacy in AI-driven omics methods	43
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Is it time to reassess variant annotation?	42
Emerging regulatory mechanisms of noncoding RNAs in topologically associating domains	42
Neoceratodus forsteri (Australian lungfish)	40
Making sense of proprioception	39
Preventing excess replication origin activation to ensure genome stability	39
Slippy-Sloppy translation: a tale of programmed and induced-ribosomal frameshifting	38
A new Down syndrome rat model races forward	38
The Emerging Roles of Cytosine-5 Methylation in mRNAs	38
Heritable epigenetic changes at single genes: challenges and opportunities in Caenorhabditis elegans	38
Evolution of Diverse Strategies for Promoter Regulation	38
Predicting genome organisation and function with mechanistic modelling	37
Out of the dark: the emerging roles of lncRNAs in pain	37
Epigenome–metabolism nexus in the retina: implications for aging and disease	36
From darkness to discovery: evolutionary, adaptive, and translational genetic insights from cavefish	36
Crossover recombination between homologous chromosomes in meiosis: recent progress and remaining mysteries	34
Gaining insight into metabolic diseases from human genetic discoveries	34
The Curious Case of Avian Sex Determination	34
Unified views on variant impact across many diseases	34
A molecular mechanism for environmental sex determination	33
Biosensing Detection of the SARS-CoV-2 D614G Mutation	33

Gene-dosage issues: a recurrent theme in whole genome duplication events	33
The complex universe of inactive PARP1	32
Leveraging spatial multiomics to unravel tissue architecture in embryo development	32
The evolution of the GALactose utilization pathway in budding yeasts	32
The sound of silence: mechanisms and implications of HUSH complex function	31
A more elaborate genetic clock for clonal species	31
The versatile relationships between eIF4E and eIF4E-interacting proteins	31
Emerging links between phase separation and transcription factor haploinsufficiency	31
The New RNA-Editing Era – Ethical Considerations	29
Cell type-specific chromatin topology and gene regulation	29
Pursuing totipotency: authentic totipotent stem cells in culture	29
Functional characterization of human genomic variation linked to polygenic diseases	28
Building the brain mosaic: an expanded view	28
The molecular basis of phenotypic evolution: beyond the usual suspects	28
Into the multiverse: advances in single-cell multiomic profiling	28
Bridging biological cfDNA features and machine learning approaches	27
Genomic instability signals offer diagnostic possibility in early cancer detection	27
Tissue specificity of DNA repair: the CRISPR compass	27
Multiple sclerosis: doubling down on MHC	27
Current concepts, advances, and challenges in deciphering the human microbiota with metatranscriptomics	27
A dive into the unknome	26
Molecular mechanisms controlling vertebrate retinal patterning, neurogenesis, and cell fate specification	25
Intron retention: importance, challenges, and opportunities	25
Long Noncoding RNAs at the Crossroads of Cell Cycle and Genome Integrity	24
Time is ticking faster for long genes in aging	24
Integration of DNA damage responses with dynamic spatial genome organization	24
FIRRM and FIGNL1: partners in the regulation of homologous recombination	24
Epigenetic networks driving T cell identity and plasticity during immunosenescence	23
Navigating the DNA methylation landscape of cancer	23
PCNA cycling dynamics during DNA replication and repair in mammals	23
Functional genomic perspectives on plant terrestrialization	23
Enhancing plant biotechnology by nanoparticle delivery of nucleic acids	23
The essential but enigmatic regulatory role of HERVH in pluripotency	22
Cryptic inclusions UNCover losses driving neurodegeneration	22
Long-read transcriptome sequencing reveals allele-specific variants at high resolution	22
Superspreading in the emergence of COVID-19 variants	21
Advances in lasso peptide discovery, biosynthesis, and function	21
The distinction between epigenetics and epigenomics	20
The ribosome’s comeback: new role in body weight regulation	20
Symbionts and gene drive: two strategies to combat vector-borne disease	20
To NMD or Not To NMD: Nonsense-Mediated mRNA Decay in Cancer and Other Genetic Diseases	20
Histone Ubiquitination: An Integrative Signaling Platform in Genome Stability	20
Achieve your research goals: a project management toolkit for graduate studies	20
A new hypothesis to explain disease dominance	19
Dynamics of replication timing during mammalian development	19
Catastrophic DNA replication in unscheduled tetraploid cells	19
Novel functions of a retroposed gene	19
Immunity and lifespan: answering long-standing questions with comparative genomics	19
Advisory Board and Contents	19
Variant-to-gene, gene-to-trait: finding new sleep genes through GWAS	18
Empowering continuous evolution of proteins by in vivo mutagenesis	18
Advisory Board and Contents	18
Unraveling the genetics of underwater caddisfly silk	18
Panicum virgatum (Poaceae)	18
Reference genome facilitates trait development for faba beans	18
Advisory Board and Contents	18
To genetic rescue or not?	18
Transperons: RNA operons as effectors of coordinated gene expression in eukaryotes	18
Advisory Board and Contents	18
'Fly-ing' from rare to common neurodegenerative disease mechanisms	18
Gene reporters for magnetic resonance imaging	17
Exploring the Alternative Splicing of Long Noncoding RNAs	17
Bear essentials	17
Advisory Board and Contents	17
Ginkgo biloba	17
Zebrafish and idiopathic scoliosis: the ‘unknown knowns’	17
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Are phenome-wide association studies feasible in a developing country?	16
Replicon-seq: seeing is believing	16
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Advisory Board and Contents	16
Variation on a theme: mapping microglial heterogeneity	16
Non-homologous end-joining at challenged replication forks: an RNA connection?	16
Advisory Board and Contents	15
On correlative and causal links of replicative epimutations	15
Picochlorum sp. SENEW3	15
Maternal plastid inheritance: two abating factors identified	15
Quantitative genetics: pan-genomes, SVs, and k-mers for GWAS	15
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Across the North Sea and beyond	15

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Genome stability from the perspective of telomere length	14
Deciphering pathogenicity of variants of uncertain significance with CRISPR-edited iPSCs	14
Viral cis-regulatory elements as sensors of cellular states and environmental cues	14
Potato trait development going fast-forward with genome editing	14
The evolution of aging and lifespan	14
Evolution of piRNA-guided defense against transposable elements	14
Start of life controlled by poly(A) tail-mediated remodeling	14
All Creatures Great and Small: New Approaches for Understanding Down Syndrome Genetics	14
Therapeutic and prognostic insights from the analysis of cancer mutational signatures	13
Towards a Human Cell Atlas: Taking Notes from the Past	13
Effective therapies for sickle cell disease: are we there yet?	13
Advisory Board and Contents	13
Single-cell dissection of tumor microenvironmental response and resistance to cancer therapy	13
Histone lactylation: epigenetic mark of glycolytic switch	13
Opportunities and challenges for artificial intelligence in clinical cardiovascular genetics	13
The chromatin roots of abnormal splicing in autism	13
RNAPII driven post-translational modifications of nucleosomal histones	12
Retrotransposon renaissance in early embryos	12
The Genetic Discrimination Observatory: confronting novel issues in genetic discrimination	12
Towards fair and clinically relevant polygenic predictions	12
Computational methods for allele-specific expression in single cells	12
HMGs as rheostats of chromosomal structure and cell proliferation	12
The genome atlas: navigating a new era of reference genomes	12
An ocean of diffusible information	11
Structure-specific nucleases: role in Okazaki fragment maturation	11
Passing down maternal dietary memories through lncRNAs	11
Recursive Test of Hardy-Weinberg Equilibrium in Tetraploids	11
Epigenetic control of muscle stem cells: time for a new dimension	11
Genetic distance informs polygenic score predictive accuracy	11
Underappreciated Roles of DNA Polymerase δ in Replication Stress Survival	11
Gene for eye placement comes into focus	11
A three-dimensional genomics view for speciation research	11
WRKY transcription factors in plant defense	10
Emerging functions of mitochondria-encoded noncoding RNAs	10
Chromatin bridges: stochastic breakage or regulated resolution?	10
Genome structural variation in human evolution	10
Multi-omic genetic scores advance disease research	10
Retention of duplicated genes in evolution	10
Aegilops tauschii presents a genetic roadmap for hexaploid wheat improvement	10
Mitochondria and G-quadruplex evolution: an intertwined relationship	10
RNA out of the mist	10
Crosstalk between epitranscriptomic and epigenetic mechanisms in gene regulation	9
Germline Variants That Affect Tumor Progression	9
First discovered, long out of sight, finally visible: ribosomal DNA	9
A devil's bargain with transposable elements in plant pathogens	9
Leveraging eco-evolutionary models for gene drive risk assessment	9
Sperm mosaicism: implications for genomic diversity and disease	9
Noncanonical DNA structures are drivers of genome evolution	9
Time will tell: comparing timescales to gain insight into transcriptional bursting	8
DNA methylation: a historical perspective	8
The Toll gene in Drosophila pattern formation	8
The multifaceted effects of YTHDC1-mediated nuclear m6A recognition	8
Mendelian randomization analyses for PCOS: evidence, opportunities, and challenges	8
Advisory Board and Contents	8
Studying transcription factor function in the genome at molecular resolution	8
Women and Minorities Encouraged to Apply (Not Stay)	8
Advisory Board and Contents	7
Advisory Board and Contents	7
Retooling conditional gene expression using a floxed exon	7
Transposons Increase Transcriptional Complexity: The Good Parasite?	7
Supergenes promote ecological stasis in a keystone species	7
Exploring the role of phage plasmids in gene transfers	7
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Advisory Board and Contents	7
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Canis familiaris (Great Dane domestic dog)	7
Advisory Board and Contents	6
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How larvae and life cycles evolve	6
Symbiodinium microadriaticum (coral microalgal endosymbiont)	6
Inferring genetic ancestry from cancer sequencing data	6
Advisory Board and Contents	6
The searchable chromosome	6
Advisory Board and Contents	6
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Opportunities and tradeoffs in single-cell transcriptomic technologies	6
Polycomb-dependent histone H2A ubiquitination links developmental disorders with cancer	6
On the evolutionary developmental biology of the cell	6
New mechanism of chromatin compartmentalization by BRD2	6
Advisory Board and Contents	6
The monk parakeet (Myiopsitta monachus)	6
Revealing microRNA regulation in single cells	6
RNA-directed DNA repair and antibody somatic hypermutation	6
Next-generation forward genetic screens: uniting high-throughput perturbations with single-cell analysis	6
Prepping for climate change by introgressive hybridization	6
Advisory Board and Contents	6
Experimental evolution of extremophile resistance to ionizing radiation	5
Technological advances in mosquito olfaction neurogenetics	5
Feralization: Confronting the Complexity of Domestication and Evolution	5
DNA base editing in nuclear and organellar genomes	5
Transcriptome-Guided Design of Physiological Multilineage Liver Organoids	5
Fine-tuning germline mutation rates across evolution	5
Gene regulation during meiosis	5