OOIR: Observatory of International Research

Papers

(The TQCC of Trends in Genetics is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Advisory Board and Contents	721
Advisory Board and Contents	709
Omics studies of DNA G-/C-quadruplexes in plants	617
Advisory Board and Contents	271
Epigenetic networks driving T cell identity and plasticity during immunosenescence	215
Carcinoscorpius rotundicauda (mangrove horseshoe crab)	190
Subscription and Copyright Information	189
Pursuing totipotency: authentic totipotent stem cells in culture	179
Genomic instability signals offer diagnostic possibility in early cancer detection	158
The complex universe of inactive PARP1	137
Genetic buffering mechanisms in SNF2-family translocases	131
Assessing autosomal aneuploidy in ancient genomes	126
Heritable epigenetic changes at single genes: challenges and opportunities in Caenorhabditis elegans	118
Superspreading in the emergence of COVID-19 variants	116
PCNA cycling dynamics during DNA replication and repair in mammals	110
Intron retention: importance, challenges, and opportunities	105
Crossover recombination between homologous chromosomes in meiosis: recent progress and remaining mysteries	100
The sound of silence: mechanisms and implications of HUSH complex function	97
Emerging regulatory mechanisms of noncoding RNAs in topologically associating domains	92
Advisory Board and Contents	89
Evolution of piRNA-guided defense against transposable elements	88
A new hypothesis to explain disease dominance	79
The chromatin roots of abnormal splicing in autism	75
Multi-omic genetic scores advance disease research	73
Variation on a theme: mapping microglial heterogeneity	73

Genome structural variation in human evolution	72
m6A in the coding sequence: linking deposition, translation, and decay	68
Immunity and lifespan: answering long-standing questions with comparative genomics	68
Histone lactylation: epigenetic mark of glycolytic switch	66
The molecular evolutionary basis of species formation revisited	64
A three-dimensional genomics view for speciation research	64
Clonal ants reveal a potentially hidden meiotic feature	61
Subscription and Copyright Information	59
Advisory Board and Contents	59
Revealing microRNA regulation in single cells	57
Animal origins: looping back in time	57
Canis familiaris (Great Dane domestic dog)	55
Advisory Board and Contents	55
Advisory Board and Contents	55
Dynamics of the Streptomyces chromosome: chance and necessity	53
Ionizing radiation damage and repair from 3D-genomic perspective	53
The making and breaking of tRNAs by ribonucleases	52
Toward DNA-based taxonomy of prokaryotes and microeukaryotes	51
DNA base editing in nuclear and organellar genomes	47
Progress and opportunities through use of genomics in animal production	47
Pioneer factors: roles and their regulation in development	46
Finding functional microproteins	45
Cis to trans: small ORF functions emerging through evolution	44
Insights into Spt6: a histone chaperone that functions in transcription, DNA replication, and genome stability	44
From genetic associations to genes: methods, applications, and challenges	42
Advisory Board and Contents	41
Subscription and Copyright Information	41
Subscription and Copyright Information	41
Subscription and Copyright Information	40
Exploring the world of small proteins in plant biology and bioengineering	39
Does TFIIH move nucleosomes?	39
Wheat genomics: genomes, pangenomes, and beyond	38
Leveraging microbiome information for animal genetic improvement	38
Protist genomics: key to understanding eukaryotic evolution	37
Genetic architecture of brain morphology and overlap with neuropsychiatric traits	37
Extracellular vesicles as modifiers of epigenomic profiles	36
Advisory Board and Contents	35
There is another: H3K27me3-mediated genomic imprinting	35
Unraveling the diversity and cultural heritage of fruit crops through paleogenomics	35
Advisory Board and Contents	35
Mapping cellular responses to DNA double-strand breaks using CRISPR technologies	34
Dissecting super-enhancer heterogeneity: time to re-examine cancer subtypes?	33
The origins and evolution of translation factors	33
mRNA-binding proteins and cell cycle progression	33
Directing RNA-modifying machineries towards endogenous RNAs: opportunities and challenges	33
Evolutionary impact of chimeric RNAs on generating phenotypic plasticity in human cells	33
Earth Biogenome Project: present status and future plans	32
Open practices in our science and our courtrooms	32
Mendel elucidated: Big Science comes to the humble garden pea	32
Positive-strand RNA virus genome replication organelles: structure, assembly, control	31

A current guide to candidate gene association studies	31
Mitochondrial-derived microproteins: from discovery to function	31
Singling out motor neurons in the age of single-cell transcriptomics	31
Rare variants and handedness: spotlight on TUBB4B	31
Genetics of human handedness: microtubules and beyond	30
Clocks at sea: the genome-editing tide is rising	30
Convergent evolution for antibiotic biosynthesis in bacteria and animals	29
Molecular circuits for genomic recording of cellular events	29
Sleeping less with a SIK3 mutation	29
Evolving a favorable distribution for mutation effects	29
The influence of transposable elements on animal colouration	29
Clonal selection parallels between normal and cancer tissues	28
Cocos nucifera (coconut)	28
Subscription and Copyright Information	27
Complex genomic rearrangements: an underestimated cause of rare diseases	26
The H2A.Z-nucleosome code in mammals: emerging functions	26
Chromoanagenesis in plants: triggers, mechanisms, and potential impact	26
Beyond sequencing: machine learning algorithms extract biology hidden in Nanopore signal data	26
Architectural RNAs: blueprints for functional membraneless organelle assembly	26
The cell as a bag of RNA	25
The rare-to-common disease journey: a winding road to new therapies	25
Subscription and Copyright Information	25
In search of a cure: PACS1 Research Foundation as a model of rare disease therapy development	25
Dosage compensation in non-model insects – progress and perspectives	25
The essential but enigmatic regulatory role of HERVH in pluripotency	24
Predicting genome organisation and function with mechanistic modelling	24
Is it time to reassess variant annotation?	24
Pathway-level convergence: an underexplored aspect of convergent evolution	24
A new Down syndrome rat model races forward	23
The versatile relationships between eIF4E and eIF4E-interacting proteins	23
Subscription and Copyright Information	23
Advisory Board and Contents	23
The impact of IDR phosphorylation on the RNA binding profiles of proteins	23
Subscription and Copyright Information	23
Subscription and Copyright Information	22
Complex diseases meet deep phenotyping and generative AI	22
Subscription and Copyright Information	22
Subscription and Copyright Information	22
Long-read transcriptome sequencing reveals allele-specific variants at high resolution	21
Repetitive elements in aging and neurodegeneration	21
Complexities of mammalian transcriptome revealed by targeted RNA enrichment techniques	21
Tissue specificity of DNA repair: the CRISPR compass	21
Into the multiverse: advances in single-cell multiomic profiling	21
Integration of DNA damage responses with dynamic spatial genome organization	21
Computational methods for allele-specific expression in single cells	20
Current concepts, advances, and challenges in deciphering the human microbiota with metatranscriptomics	20
Emerging insights into the genetics and evolution of human same-sex sexual behavior	20
Across the North Sea and beyond	19
Bear essentials	19
The ribosome’s comeback: new role in body weight regulation	18
DNA lesions piece together impossible trees	18
Advisory Board and Contents	18
Subscription and Copyright Information	18
Cross-kingdom RNA communication in plant–bacterial interaction	18
Genomic newborn screening: exploring opportunities and navigating pitfalls while ensuring inclusivity	18
Noncanonical DNA structures are drivers of genome evolution	18
Advisory Board and Contents	18
Dynamics of replication timing during mammalian development	18
Are phenome-wide association studies feasible in a developing country?	18
Genome stability from the perspective of telomere length	18
Mendelian randomization analyses for PCOS: evidence, opportunities, and challenges	17
Mitochondria and G-quadruplex evolution: an intertwined relationship	17
Emerging functions of mitochondria-encoded noncoding RNAs	17
Zebrafish and idiopathic scoliosis: the ‘unknown knowns’	16
Maturation and application of phenome-wide association studies	16
Modeling the origin of cells	16
DNA methylation: a historical perspective	16
Advisory Board and Contents	16
Whole-genome doubling in tissues and tumors	15
Honeybees’ novel complementary sex-determining system: function and origin	15
Chromatin accessibility provides a window into the genetic etiology of human brain disease	15
Approaches and challenges in genome-wide circular RNA identification and quantification	15
The searchable chromosome	15
Opportunities and tradeoffs in single-cell transcriptomic technologies	15
The wild side of grape genomics	15
Subscription and Copyright Information	15
Optimizing homology-directed repair for gene editing: the potential of single-stranded DNA donors	15