Trends in Genetics

Papers
(The TQCC of Trends in Genetics is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Subscription and Copyright Information607
Advisory Board and Contents579
Emerging regulatory mechanisms of noncoding RNAs in topologically associating domains474
Crossover recombination between homologous chromosomes in meiosis: recent progress and remaining mysteries257
Subscription and Copyright Information202
Advisory Board and Contents176
Advisory Board and Contents170
Genomic instability signals offer diagnostic possibility in early cancer detection160
Genetic buffering mechanisms in SNF2-family translocases155
Long Noncoding RNAs at the Crossroads of Cell Cycle and Genome Integrity147
Emerging functions of circular RNA in aging145
The complex universe of inactive PARP1140
Pursuing totipotency: authentic totipotent stem cells in culture133
Epigenetic networks driving T cell identity and plasticity during immunosenescence119
Carcinoscorpius rotundicauda (mangrove horseshoe crab)116
Omics studies of DNA G-/C-quadruplexes in plants108
Assessing autosomal aneuploidy in ancient genomes105
Heritable epigenetic changes at single genes: challenges and opportunities in Caenorhabditis elegans101
PCNA cycling dynamics during DNA replication and repair in mammals100
Superspreading in the emergence of COVID-19 variants96
The sound of silence: mechanisms and implications of HUSH complex function88
Intron retention: importance, challenges, and opportunities81
Advisory Board and Contents80
Variation on a theme: mapping microglial heterogeneity78
Opportunities and challenges for artificial intelligence in clinical cardiovascular genetics78
A new hypothesis to explain disease dominance73
Multi-omic genetic scores advance disease research72
Evolution of piRNA-guided defense against transposable elements70
Immunity and lifespan: answering long-standing questions with comparative genomics70
Genome structural variation in human evolution69
A three-dimensional genomics view for speciation research67
The chromatin roots of abnormal splicing in autism67
Histone lactylation: epigenetic mark of glycolytic switch66
Advisory Board and Contents64
Clonal ants reveal a potentially hidden meiotic feature62
Advisory Board and Contents59
Subscription and Copyright Information59
Cis to trans: small ORF functions emerging through evolution58
The making and breaking of tRNAs by ribonucleases58
Dynamics of the Streptomyces chromosome: chance and necessity54
Finding functional microproteins52
Ionizing radiation damage and repair from 3D-genomic perspective52
Canis familiaris (Great Dane domestic dog)51
DNA base editing in nuclear and organellar genomes48
Progress and opportunities through use of genomics in animal production48
Revealing microRNA regulation in single cells48
Insights into Spt6: a histone chaperone that functions in transcription, DNA replication, and genome stability47
Pioneer factors: roles and their regulation in development47
From genetic associations to genes: methods, applications, and challenges47
Advisory Board and Contents46
Genetic architecture of brain morphology and overlap with neuropsychiatric traits46
Exploring the world of small proteins in plant biology and bioengineering45
Subscription and Copyright Information45
Subscription and Copyright Information45
Unraveling the diversity and cultural heritage of fruit crops through paleogenomics44
Leveraging microbiome information for animal genetic improvement44
Does TFIIH move nucleosomes?42
Extracellular vesicles as modifiers of epigenomic profiles42
From QTL to gene: C. elegans facilitates discoveries of the genetic mechanisms underlying natural variation40
Wheat genomics: genomes, pangenomes, and beyond40
The Nexus of cfDNA and Nuclease Biology39
mRNA-binding proteins and cell cycle progression39
Callithrix jacchus (the common marmoset)39
Advisory Board and Contents38
Advisory Board and Contents38
The origins and evolution of translation factors37
Evolutionary impact of chimeric RNAs on generating phenotypic plasticity in human cells36
Positive-strand RNA virus genome replication organelles: structure, assembly, control36
Dissecting super-enhancer heterogeneity: time to re-examine cancer subtypes?36
Earth Biogenome Project: present status and future plans36
Directing RNA-modifying machineries towards endogenous RNAs: opportunities and challenges35
A current guide to candidate gene association studies35
There is another: H3K27me3-mediated genomic imprinting34
Singling out motor neurons in the age of single-cell transcriptomics34
Open practices in our science and our courtrooms34
Mapping cellular responses to DNA double-strand breaks using CRISPR technologies33
Transcriptional Silencers: Driving Gene Expression with the Brakes On33
Polycomb Gene Silencing Mechanisms: PRC2 Chromatin Targeting, H3K27me3 'Readout', and Phase Separation-Based Compaction33
Clonal selection parallels between normal and cancer tissues32
Low-cost CRISPR diagnostics for resource-limited settings31
Subscription and Copyright Information31
Convergent evolution for antibiotic biosynthesis in bacteria and animals30
The influence of transposable elements on animal colouration30
Clocks at sea: the genome-editing tide is rising30
Research and leaders: a twisted tale!29
Cocos nucifera (coconut)29
The cell as a bag of RNA29
Chromoanagenesis in plants: triggers, mechanisms, and potential impact28
Rare variants and handedness: spotlight on TUBB4B27
Evolving a favorable distribution for mutation effects27
Dosage compensation in non-model insects – progress and perspectives27
Molecular circuits for genomic recording of cellular events27
Horizontal Gene Transfer in Vertebrates: A Fishy Tale26
Mitochondrial-derived microproteins: from discovery to function26
Complex genomic rearrangements: an underestimated cause of rare diseases25
Genetics of human handedness: microtubules and beyond25
Subscription and Copyright Information24
Subscription and Copyright Information24
Subscription and Copyright Information24
Advisory Board and Contents24
Beyond sequencing: machine learning algorithms extract biology hidden in Nanopore signal data24
The H2A.Z-nucleosome code in mammals: emerging functions24
The Curious Case of Avian Sex Determination24
A new Down syndrome rat model races forward23
Is it time to reassess variant annotation?23
The impact of IDR phosphorylation on the RNA binding profiles of proteins22
Long-read transcriptome sequencing reveals allele-specific variants at high resolution22
Subscription and Copyright Information22
Complexities of mammalian transcriptome revealed by targeted RNA enrichment techniques22
Driving to Safety: CRISPR-Based Genetic Approaches to Reducing Antibiotic Resistance22
Subscription and Copyright Information22
Integration of DNA damage responses with dynamic spatial genome organization22
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Histone Ubiquitination: An Integrative Signaling Platform in Genome Stability21
Current concepts, advances, and challenges in deciphering the human microbiota with metatranscriptomics21
Predicting genome organisation and function with mechanistic modelling21
The versatile relationships between eIF4E and eIF4E-interacting proteins21
Tissue specificity of DNA repair: the CRISPR compass21
Emerging insights into the genetics and evolution of human same-sex sexual behavior21
In search of a cure: PACS1 Research Foundation as a model of rare disease therapy development21
Into the multiverse: advances in single-cell multiomic profiling21
The essential but enigmatic regulatory role of HERVH in pluripotency20
Repetitive elements in aging and neurodegeneration20
Are phenome-wide association studies feasible in a developing country?19
Across the North Sea and beyond19
Zebrafish and idiopathic scoliosis: the ‘unknown knowns’19
Subscription and Copyright Information19
Advisory Board and Contents19
Dynamics of replication timing during mammalian development19
Advisory Board and Contents19
Bear essentials18
Computational methods for allele-specific expression in single cells18
The genome atlas: navigating a new era of reference genomes18
The ribosome’s comeback: new role in body weight regulation18
Recursive Test of Hardy-Weinberg Equilibrium in Tetraploids18
Genomic newborn screening: exploring opportunities and navigating pitfalls while ensuring inclusivity17
Mendelian randomization analyses for PCOS: evidence, opportunities, and challenges17
DNA lesions piece together impossible trees17
Mitochondria and G-quadruplex evolution: an intertwined relationship17
Quantitative genetics: pan-genomes, SVs, and k-mers for GWAS17
Genome stability from the perspective of telomere length17
The searchable chromosome16
Honeybees’ novel complementary sex-determining system: function and origin16
Chromatin accessibility provides a window into the genetic etiology of human brain disease16
Advisory Board and Contents16
Emerging functions of mitochondria-encoded noncoding RNAs16
Subscription and Copyright Information16
Mitochondrial-derived microproteins: from discovery to function16
DNA methylation: a historical perspective16
Noncanonical DNA structures are drivers of genome evolution16
Whole-genome doubling in tissues and tumors16
Modeling the origin of cells15
Approaches and challenges in genome-wide circular RNA identification and quantification15
Opportunities and tradeoffs in single-cell transcriptomic technologies15
Insights from multi-omics integration in complex disease primary tissues15
Maturation and application of phenome-wide association studies15
The wild side of grape genomics15
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