OOIR: Observatory of International Research

Papers

(The TQCC of Trends in Genetics is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Subscription and Copyright Information	681
Advisory Board and Contents	655
Emerging regulatory mechanisms of noncoding RNAs in topologically associating domains	558
Advisory Board and Contents	240
Advisory Board and Contents	194
Genetic buffering mechanisms in SNF2-family translocases	171
Epigenetic networks driving T cell identity and plasticity during immunosenescence	168
Carcinoscorpius rotundicauda (mangrove horseshoe crab)	166
Omics studies of DNA G-/C-quadruplexes in plants	153
Assessing autosomal aneuploidy in ancient genomes	133
Superspreading in the emergence of COVID-19 variants	123
Genomic instability signals offer diagnostic possibility in early cancer detection	119
Heritable epigenetic changes at single genes: challenges and opportunities in Caenorhabditis elegans	112
PCNA cycling dynamics during DNA replication and repair in mammals	112
The sound of silence: mechanisms and implications of HUSH complex function	100
Emerging functions of circular RNA in aging	91
Crossover recombination between homologous chromosomes in meiosis: recent progress and remaining mysteries	88
The complex universe of inactive PARP1	83
Intron retention: importance, challenges, and opportunities	82
Pursuing totipotency: authentic totipotent stem cells in culture	79
Advisory Board and Contents	77
Opportunities and challenges for artificial intelligence in clinical cardiovascular genetics	73
Variation on a theme: mapping microglial heterogeneity	73
A new hypothesis to explain disease dominance	72
A three-dimensional genomics view for speciation research	70

The molecular evolutionary basis of species formation revisited	68
Multi-omic genetic scores advance disease research	67
Immunity and lifespan: answering long-standing questions with comparative genomics	66
Evolution of piRNA-guided defense against transposable elements	63
m6A in the coding sequence: linking deposition, translation, and decay	63
The chromatin roots of abnormal splicing in autism	61
Histone lactylation: epigenetic mark of glycolytic switch	60
Genome structural variation in human evolution	60
Advisory Board and Contents	59
Clonal ants reveal a potentially hidden meiotic feature	57
Revealing microRNA regulation in single cells	55
Advisory Board and Contents	54
The making and breaking of tRNAs by ribonucleases	54
Subscription and Copyright Information	54
Canis familiaris (Great Dane domestic dog)	54
Animal origins: looping back in time	52
Progress and opportunities through use of genomics in animal production	52
Ionizing radiation damage and repair from 3D-genomic perspective	52
Cis to trans: small ORF functions emerging through evolution	51
Insights into Spt6: a histone chaperone that functions in transcription, DNA replication, and genome stability	50
Dynamics of the Streptomyces chromosome: chance and necessity	49
Finding functional microproteins	49
Toward DNA-based taxonomy of prokaryotes and microeukaryotes	48
Pioneer factors: roles and their regulation in development	48
DNA base editing in nuclear and organellar genomes	44
Advisory Board and Contents	44
From genetic associations to genes: methods, applications, and challenges	44
Genetic architecture of brain morphology and overlap with neuropsychiatric traits	42
Subscription and Copyright Information	41
Does TFIIH move nucleosomes?	40
Subscription and Copyright Information	40
Leveraging microbiome information for animal genetic improvement	39
Subscription and Copyright Information	38
Unraveling the diversity and cultural heritage of fruit crops through paleogenomics	38
Exploring the world of small proteins in plant biology and bioengineering	37
Extracellular vesicles as modifiers of epigenomic profiles	37
From QTL to gene: C. elegans facilitates discoveries of the genetic mechanisms underlying natural variation	37
Protist genomics: key to understanding eukaryotic evolution	37
Wheat genomics: genomes, pangenomes, and beyond	37
mRNA-binding proteins and cell cycle progression	36
Advisory Board and Contents	36
Evolutionary impact of chimeric RNAs on generating phenotypic plasticity in human cells	35
Dissecting super-enhancer heterogeneity: time to re-examine cancer subtypes?	33
Advisory Board and Contents	33
Mendel elucidated: Big Science comes to the humble garden pea	31
Mapping cellular responses to DNA double-strand breaks using CRISPR technologies	31
A current guide to candidate gene association studies	31
Callithrix jacchus (the common marmoset)	31
Open practices in our science and our courtrooms	31
The origins and evolution of translation factors	31

Earth Biogenome Project: present status and future plans	31
There is another: H3K27me3-mediated genomic imprinting	30
Directing RNA-modifying machineries towards endogenous RNAs: opportunities and challenges	30
Singling out motor neurons in the age of single-cell transcriptomics	29
Positive-strand RNA virus genome replication organelles: structure, assembly, control	29
Clonal selection parallels between normal and cancer tissues	29
Subscription and Copyright Information	28
Rare variants and handedness: spotlight on TUBB4B	28
Convergent evolution for antibiotic biosynthesis in bacteria and animals	28
Research and leaders: a twisted tale!	27
Evolving a favorable distribution for mutation effects	27
Cocos nucifera (coconut)	27
Architectural RNAs: blueprints for functional membraneless organelle assembly	26
Clocks at sea: the genome-editing tide is rising	26
Low-cost CRISPR diagnostics for resource-limited settings	26
Sleeping less with a SIK3 mutation	26
Molecular circuits for genomic recording of cellular events	25
The H2A.Z-nucleosome code in mammals: emerging functions	25
Dosage compensation in non-model insects – progress and perspectives	25
The influence of transposable elements on animal colouration	25
Mitochondrial-derived microproteins: from discovery to function	24
Complex genomic rearrangements: an underestimated cause of rare diseases	24
Genetics of human handedness: microtubules and beyond	24
Beyond sequencing: machine learning algorithms extract biology hidden in Nanopore signal data	24
The cell as a bag of RNA	24
Chromoanagenesis in plants: triggers, mechanisms, and potential impact	24
Advisory Board and Contents	23
Subscription and Copyright Information	23
Subscription and Copyright Information	23
Subscription and Copyright Information	22
Subscription and Copyright Information	22
The impact of IDR phosphorylation on the RNA binding profiles of proteins	22
Is it time to reassess variant annotation?	22
A new Down syndrome rat model races forward	22
In search of a cure: PACS1 Research Foundation as a model of rare disease therapy development	22
Subscription and Copyright Information	22
Complexities of mammalian transcriptome revealed by targeted RNA enrichment techniques	22
Subscription and Copyright Information	22
The versatile relationships between eIF4E and eIF4E-interacting proteins	21
Emerging insights into the genetics and evolution of human same-sex sexual behavior	21
The rare-to-common disease journey: a winding road to new therapies	21
Pathway-level convergence: an underexplored aspect of convergent evolution	21
Current concepts, advances, and challenges in deciphering the human microbiota with metatranscriptomics	21
Tissue specificity of DNA repair: the CRISPR compass	21
Predicting genome organisation and function with mechanistic modelling	20
Integration of DNA damage responses with dynamic spatial genome organization	20
Advisory Board and Contents	20
Repetitive elements in aging and neurodegeneration	20
Long-read transcriptome sequencing reveals allele-specific variants at high resolution	20
Into the multiverse: advances in single-cell multiomic profiling	20
The essential but enigmatic regulatory role of HERVH in pluripotency	20
Across the North Sea and beyond	19
Subscription and Copyright Information	19
Advisory Board and Contents	19
The ribosome’s comeback: new role in body weight regulation	18
Subscription and Copyright Information	18
The genome atlas: navigating a new era of reference genomes	18
Are phenome-wide association studies feasible in a developing country?	18
DNA lesions piece together impossible trees	18
Bear essentials	18
Dynamics of replication timing during mammalian development	18
Zebrafish and idiopathic scoliosis: the ‘unknown knowns’	17
Quantitative genetics: pan-genomes, SVs, and k-mers for GWAS	17
Genomic newborn screening: exploring opportunities and navigating pitfalls while ensuring inclusivity	17
Mitochondria and G-quadruplex evolution: an intertwined relationship	17
Cross-kingdom RNA communication in plant–bacterial interaction	17
Noncanonical DNA structures are drivers of genome evolution	16
Emerging functions of mitochondria-encoded noncoding RNAs	16
Mendelian randomization analyses for PCOS: evidence, opportunities, and challenges	16
Genome stability from the perspective of telomere length	16
DNA methylation: a historical perspective	16
Computational methods for allele-specific expression in single cells	16
Subscription and Copyright Information	16
Honeybees’ novel complementary sex-determining system: function and origin	15
Maturation and application of phenome-wide association studies	15
The wild side of grape genomics	15
The searchable chromosome	15
Modeling the origin of cells	15
Advisory Board and Contents	15