OOIR: Observatory of International Research

Papers

(The TQCC of Trends in Genetics is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Advisory Board and Contents	733
Crossover recombination between homologous chromosomes in meiosis: recent progress and remaining mysteries	639
Emerging regulatory mechanisms of noncoding RNAs in topologically associating domains	285
Advisory Board and Contents	220
Omics studies of DNA G-/C-quadruplexes in plants	210
Epigenetic networks driving T cell identity and plasticity during immunosenescence	194
Carcinoscorpius rotundicauda (mangrove horseshoe crab)	188
Subscription and Copyright Information	161
Superspreading in the emergence of COVID-19 variants	142
Genetic buffering mechanisms in SNF2-family translocases	138
Assessing autosomal aneuploidy in ancient genomes	129
Heritable epigenetic changes at single genes: challenges and opportunities in Caenorhabditis elegans	117
Pursuing totipotency: authentic totipotent stem cells in culture	113
Intron retention: importance, challenges, and opportunities	112
PCNA cycling dynamics during DNA replication and repair in mammals	101
The sound of silence: mechanisms and implications of HUSH complex function	99
Advisory Board and Contents	92
The complex universe of inactive PARP1	92
Advisory Board and Contents	90
A new hypothesis to explain disease dominance	81
Evolution of piRNA-guided defense against transposable elements	81
Variation on a theme: mapping microglial heterogeneity	78
The chromatin roots of abnormal splicing in autism	75
A three-dimensional genomics view for speciation research	74
Immunity and lifespan: answering long-standing questions with comparative genomics	69

m6A in the coding sequence: linking deposition, translation, and decay	69
Multi-omic genetic scores advance disease research	68
Genome structural variation in human evolution	66
Histone lactylation: epigenetic mark of glycolytic switch	64
The molecular evolutionary basis of species formation revisited	62
Clonal ants reveal a potentially hidden meiotic feature	60
Canis familiaris (Great Dane domestic dog)	59
Subscription and Copyright Information	59
Advisory Board and Contents	59
Animal origins: looping back in time	58
Advisory Board and Contents	58
The making and breaking of tRNAs by ribonucleases	57
Advisory Board and Contents	57
Toward DNA-based taxonomy of prokaryotes and microeukaryotes	55
Ionizing radiation damage and repair from 3D-genomic perspective	54
DNA base editing in nuclear and organellar genomes	50
From genetic associations to genes: methods, applications, and challenges	48
Pioneer factors: roles and their regulation in development	48
Progress and opportunities through use of genomics in animal production	48
Insights into Spt6: a histone chaperone that functions in transcription, DNA replication, and genome stability	46
Revealing microRNA regulation in single cells	45
Dynamics of the Streptomyces chromosome: chance and necessity	45
Cis to trans: small ORF functions emerging through evolution	43
Subscription and Copyright Information	43
Finding functional microproteins	43
Advisory Board and Contents	43
Subscription and Copyright Information	42
Subscription and Copyright Information	41
Does TFIIH move nucleosomes?	40
Protist genomics: key to understanding eukaryotic evolution	39
Exploring the world of small proteins in plant biology and bioengineering	39
Unraveling the diversity and cultural heritage of fruit crops through paleogenomics	39
The illusion of clarity in familiar genetics diagrams	38
Genetic architecture of brain morphology and overlap with neuropsychiatric traits	37
Wheat genomics: genomes, pangenomes, and beyond	37
In silico genome transplants and the cis-regulatory basis of biodiversity	36
Leveraging microbiome information for animal genetic improvement	36
Extracellular vesicles as modifiers of epigenomic profiles	35
Advisory Board and Contents	35
Advisory Board and Contents	35
Open practices in our science and our courtrooms	34
There is another: H3K27me3-mediated genomic imprinting	34
Dissecting super-enhancer heterogeneity: time to re-examine cancer subtypes?	34
The origins and evolution of translation factors	34
A current guide to candidate gene association studies	34
Mendel elucidated: Big Science comes to the humble garden pea	33
Evolutionary impact of chimeric RNAs on generating phenotypic plasticity in human cells	33
Mapping cellular responses to DNA double-strand breaks using CRISPR technologies	33
Singling out motor neurons in the age of single-cell transcriptomics	33
Directing RNA-modifying machineries towards endogenous RNAs: opportunities and challenges	33

Positive-strand RNA virus genome replication organelles: structure, assembly, control	32
mRNA-binding proteins and cell cycle progression	32
Earth Biogenome Project: present status and future plans	32
Rare variants and handedness: spotlight on TUBB4B	31
Sleeping less with a SIK3 mutation	30
Clocks at sea: the genome-editing tide is rising	30
Clonal selection parallels between normal and cancer tissues	30
Convergent evolution for antibiotic biosynthesis in bacteria and animals	30
Cocos nucifera (coconut)	29
Chromoanagenesis in plants: triggers, mechanisms, and potential impact	28
The H2A.Z-nucleosome code in mammals: emerging functions	28
Subscription and Copyright Information	28
The influence of transposable elements on animal colouration	28
Dosage compensation in non-model insects – progress and perspectives	27
Architectural RNAs: blueprints for functional membraneless organelle assembly	27
Complex genomic rearrangements: an underestimated cause of rare diseases	27
The cell as a bag of RNA	27
Molecular circuits for genomic recording of cellular events	27
Evolving a favorable distribution for mutation effects	26
Genetics of human handedness: microtubules and beyond	26
Beyond sequencing: machine learning algorithms extract biology hidden in Nanopore signal data	26
Mitochondrial-derived microproteins: from discovery to function	25
Subscription and Copyright Information	25
Is it time to reassess variant annotation?	24
Subscription and Copyright Information	24
A new Down syndrome rat model races forward	24
Subscription and Copyright Information	24
Pathway-level convergence: an underexplored aspect of convergent evolution	24
Subscription and Copyright Information	23
Subscription and Copyright Information	23
Advisory Board and Contents	23
Subscription and Copyright Information	23
The versatile relationships between eIF4E and eIF4E-interacting proteins	23
Complexities of mammalian transcriptome revealed by targeted RNA enrichment techniques	22
Predicting genome organisation and function with mechanistic modelling	22
Integration of DNA damage responses with dynamic spatial genome organization	22
In search of a cure: PACS1 Research Foundation as a model of rare disease therapy development	22
The impact of IDR phosphorylation on the RNA binding profiles of proteins	22
Long-read transcriptome sequencing reveals allele-specific variants at high resolution	22
Complex diseases meet deep phenotyping and generative AI	21
Into the multiverse: advances in single-cell multiomic profiling	20
Repetitive elements in aging and neurodegeneration	20
The rare-to-common disease journey: a winding road to new therapies	20
Emerging insights into the genetics and evolution of human same-sex sexual behavior	20
The essential but enigmatic regulatory role of HERVH in pluripotency	20
Current concepts, advances, and challenges in deciphering the human microbiota with metatranscriptomics	20
Genomic newborn screening: exploring opportunities and navigating pitfalls while ensuring inclusivity	19
Across the North Sea and beyond	19
The ribosome’s comeback: new role in body weight regulation	19
Bear essentials	19
Are phenome-wide association studies feasible in a developing country?	19
Advisory Board and Contents	19
DNA lesions piece together impossible trees	18
Computational methods for allele-specific expression in single cells	18
Subscription and Copyright Information	18
Cross-kingdom RNA communication in plant–bacterial interaction	18
Advisory Board and Contents	18
Zebrafish and idiopathic scoliosis: the ‘unknown knowns’	18
Dynamics of replication timing during mammalian development	17
Noncanonical DNA structures are drivers of genome evolution	17
Emerging functions of mitochondria-encoded noncoding RNAs	17
Genome stability from the perspective of telomere length	17
Maturation and application of phenome-wide association studies	16
Advisory Board and Contents	16
Mitochondria and G-quadruplex evolution: an intertwined relationship	16
Mendelian randomization analyses for PCOS: evidence, opportunities, and challenges	16
DNA methylation: a historical perspective	16
Modeling the origin of cells	16
The wild side of grape genomics	15
Optimizing homology-directed repair for gene editing: the potential of single-stranded DNA donors	15
Opportunities and tradeoffs in single-cell transcriptomic technologies	15
Mitochondrial-derived microproteins: from discovery to function	15
The searchable chromosome	15
Chromatin accessibility provides a window into the genetic etiology of human brain disease	15
Honeybees’ novel complementary sex-determining system: function and origin	15
Subscription and Copyright Information	15