Computer Methods and Programs in Biomedicine

Article	Citations
Influence of genetic mutations to atria vulnerability to atrial fibrillation: An in-silico 3D human atria study	658
Modelling of cardiac biventricular electromechanics with coronary blood flow to investigate the influence of coronary arterial motion on coronary haemodynamic	540
Influence of therapeutic grip exercises induced loading rates in distal radius fracture healing with volar locking plate fixation	293
Temporal convolutional neural network-based feature extraction and asynchronous channel information fusion method for heart abnormality detection in phonocardiograms	241
An interactive and realistic phantom for cricothyroidotomy simulation of a patient with obesity through a reusable design using 3D-printing and Arduino	237
Evaluation of cerebrovascular hemodynamics in vascular dementia patients with a new individual computational fluid dynamics algorithm	205
Editorial Board	191
4-dimensional local radial basis function interpolation of large, uniformly spaced datasets	187
CUAMT: A MRI semi-supervised medical image segmentation framework based on contextual information and mixed uncertainty	184
Dual-modeling computational framework of magnetoelectric core-shell nanoparticles and nanochain for wireless peripheral nerve regeneration	165
Finite element analysis of conductive hearing loss caused by fixation and detachment of ligament and tendon in the middle ear	152
Modelling lower-limb peripheral arterial disease using clinically available datasets: impact of inflow boundary conditions on hemodynamic indices for restenosis prediction	138
IODeep: An IOD for the introduction of deep learning in the DICOM standard	133
Using machine learning models for predicting monthly iPTH levels in hemodialysis patients	131
Using AI and passive medical radiometry for diagnostics (MWR) of venous diseases	126
Unsupervised domain adaptation for nuclei segmentation: Adapting from hematoxylin & eosin stained slides to immunohistochemistry stained slides using a curriculum approach	111
Multimodal radiomics based on lesion connectome predicts stroke prognosis	104
Computer modeling of radiofrequency cardiac ablation: 30 years of bioengineering research	103
MEFA-Unet: Multi-Scale Feature Extraction and Fusion Attentional Unet for Segmenting Short Process Of Incus in Otologic Microsurgical Scenarios	98
MSigSeg: An R package for multiple signals segmentation	94
A temporal convolutional network-based approach and a benchmark dataset for colonoscopy video temporal segmentation	92
Differential evolution method to find optimal location of a single-element transducer for transcranial focused ultrasound therapy	89
A real-time computer-aided diagnosis method for hydatidiform mole recognition using deep neural network	89
VesselKnife – software for the analysis of tubular structures in biomedical images	88
Prediction of neoadjuvant therapy response to HER2-positive and triple-negative breast cancer: a multicenter proof-of-concept study	88

Raw photoplethysmogram waveforms versus peak-to-peak intervals for machine learning detection of atrial fibrillation: Does waveform matter?	88
Cuffless blood pressure estimation using chaotic features of photoplethysmograms and parallel convolutional neural network	82
A cloud-based consultation and collaboration system for radiotherapy: Remote decision support services for community radiotherapy centers	81
The impact of small movements with dual lumen cannulae during venovenous extracorporeal membrane oxygenation: A computational fluid dynamics analysis	80
FMCW radar based high-precision gridless non-contact vital signs monitoring for Internet of Medical Things	79
SC-Net: Symmetrical conical network for colorectal pathology image segmentation	78
CAPNet: Context attention pyramid network for computer-aided detection of microcalcification clusters in digital breast tomosynthesis	76
CTGAN-driven synthetic data generation: A multidisciplinary, expert-guided approach (TIMA)	76
Dynamic-MRI quantification of abdominal wall motion and deformation during breathing and muscular contraction	75
Biomechanical analysis of all-polyethylene total knee arthroplasty on periprosthetic tibia using the finite element method	75
Fear of falling in community-dwelling older adults: What their gait acceleration pattern reveals	75
Integrative analysis of RNA modification-related gene PUS7 in diagnosis, prognosis, and tumor microenvironment of hepatocellular carcinoma	72
Evaluation of deep learning training strategies for the classification of bone marrow cell images	71
MBGA-Net: A multi-branch graph adaptive network for individualized motor imagery EEG classification	69
Computer-aided detection and segmentation of malignant melanoma lesions on whole-body 18	69
An ensemble classifier for emotion classification from EEG and GSR signals for autism detection	68
Unsupervised band selection of medical hyperspectral images guided by data gravitation and weak correlation	67
Light&fast generative adversarial network for high-fidelity CT image synthesis of liver tumor	66
Optimal machine learning methods for prediction of high-flow nasal cannula outcomes using image features from electrical impedance tomography	65
Real-time soft body dissection simulation with parallelized graph-based shape matching on GPU	64
Lung nodule classification using radiomics model trained on degraded SDCT images	63
Importance of the enhanced cooling system for more spherical ablation zones: Numerical simulation, ex vivo and in vivo validation	63
CPSS: Fusing consistency regularization and pseudo-labeling techniques for semi-supervised deep cardiovascular disease detection using all unlabeled electrocardiograms	62
Artery vein classification in fundus images using serially connected U-Nets	61
A study on brain tumor dynamics in two-dimensional irregular domain with variable-order time-fractional derivative	61
VOC-DL: Deep learning prediction model for COVID-19 based on VOC virus variants	58
An automatic pipeline for atlas-based fetal and neonatal brain segmentation and analysis	58
Prediction of the mode of delivery using artificial intelligence algorithms	56
Medical image super-resolution reconstruction algorithms based on deep learning: A survey	55
A Graph-guided Hybrid Regularization Method For Bioluminescence Tomography	54
Identifying the patient harms to include in an in silico clinical trial	53
SIMUS3: An open-source simulator for 3-D ultrasound imaging	53
From local counterfactuals to global feature importance: efficient, robust, and model-agnostic explanations for brain connectivity networks	52
KUB-UNet: Segmentation of Organs of Urinary System from a KUB X-ray Image	51
Recurrence quantification analysis of rs-fMRI data: A method to detect subtle changes in the TgF344-AD rat model	51
Multi-scale simulation of red blood cell trauma in large-scale high-shear flows after Norwood operation	51
Corrigendum to “Generation of post-meal insulin correction boluses in type 1 diabetes simulation models for in-silico clinical trials: More realistic scenarios obtained using a decision tree approach”	51
Multi-electrode catheter PFA: Computational modeling and in vivo validation of lesion dynamics under energy-dose variants	51
Corticosteroid sensitivity detection in sepsis patients using a personalized data mining approach: A clinical investigation	50
SMD-YOLO: An efficient and lightweight detection method for mask wearing status during the COVID-19 pandemic	50
Multi-scale dual-channel feature embedding decoder for biomedical image segmentation	49
Molecular dynamics simulation of hyaluronic acid hydrogels: Effect of water content on mechanical and tribological properties	49
An improved binary particle swarm optimization algorithm for clinical cancer biomarker identification in microarray data	49
Dynamic elastic modulus assessment of the early degeneration model of an intervertebral disc in cynomolgus monkeys with one strike loading	48
Haemosync: A synchronisation algorithm for multimodal haemodynamic signals	48
Data-driven sleep structure deciphering based on cardiorespiratory signals	47
Health classification of Meibomian gland images using keratography 5M based on AlexNet model	47
A framework for motor imagery with LSTM neural network	46
TGMIL: A hybrid multi-instance learning model based on the Transformer and the Graph Attention Network for whole-slide images classification of renal cell carcinoma	46
Extension of physical activity recognition with 3D CNN using encrypted multiple sensory data to federated learning based on multi-key homomorphic encryption	46

Artificial intelligence model for tumoral clinical decision support systems	46
SFTNet: A microexpression-based method for depression detection	46
TransAnno-Net: A Deep Learning Framework for Accurate Cell Type Annotation of Mouse Lung Tissue Using Self-supervised Pretraining	45
A myocardial reorientation method based on feature point detection for quantitative analysis of PET myocardial perfusion imaging	45
Integrating prior knowledge with deep learning for optimized quality control in corneal images: A multicenter study	45
A computational method to predict cerebral perfusion flow after endovascular treatment based on invasive pressure and resistance	45
PyMIC: A deep learning toolkit for annotation-efficient medical image segmentation	45
Prediction of iliac limb occlusion after endovascular aneurysm repair for abdominal aortic aneurysm by anatomical and near-wall hemodynamic characteristics combining numerical simulation and in vitro	44
Simulation-driven optimization of insulin therapy profiles in a commercial hybrid closed-loop system	44
Corrigendum to “Segmentation of skin layers on HFUS images using the attention mechanism”, [Computer Methods and Programs in Biomedicine, 263 (2025) 108668]	43
A numerical simulation study of soft tissue resection for low-damage precision cancer surgery	43
A multi-task learning model with reinforcement optimization for ASD comorbidity discrimination	43
Evaluation of the linear and nonlinear classifiers for distinguishing between healthy subjects and patients with valvular heart diseases based on electrocardiograms, seismocardiograms, and gyrocardiog	43
Modified Theoretical Model Predicts Radial Support Capacity of Polymer Braided Stents	42
Predicting 6-minute walking test outcomes in patients with chronic obstructive pulmonary disease without physical performance measures	42
A computer based facial flaps simulator using projective dynamics	42
FM-Net: Deep Learning Network for the Fundamental Matrix Estimation from Biplanar Radiographs	41
United multi-task learning for abdominal contrast-enhanced CT synthesis through joint deformable registration	41
Multicentric intelligent cardiotocography signal interpretation using deep semi-supervised domain adaptation via minimax entropy and domain invariance	40
Digital signal extraction approach for cardiotocography image	40
Phys-DAT: A physiologically-based pharmacokinetic model for unraveling the dissolution, transit and absorption processes using PhysPK®	40
Editorial Board	40
Retinex-qDPC: Automatic background-rectified quantitative differential phase contrast imaging	39
Editorial Board	39
A deformation model of pulsating brain tissue for neurosurgery simulation	38
Editorial Board	38
A probabilistic generative model to discover the treatments of coexisting diseases with missing data	38
A multiconsistent computational methodology to resolve a diffusive epidemiological system with effects of migration, vaccination and quarantine	38
Missing data imputation using utility-based regression and sampling approaches	38
Phantom study of an in-house amplitude-gating respiratory method with silicon photomultiplier technology positron emission tomography/computed tomography	38
Improving convolutional neural network learning based on a hierarchical bezier generative model for stenosis detection in X-ray images	37
A simple agent-based hybrid model to simulate the biophysics of glioblastoma multiforme cells and the concomitant evolution of the oxygen field	37
Facial expressions to identify post-stroke: A pilot study	37
In-silico neuro musculoskeletal model reproduces the movement types obtained by spinal micro stimulation	37
Reallocation of cutaneous and global blood circulation during sauna bathing through a closed-loop model	37
MRCON-Net: Multiscale reweighted convolutional coding neural network for low-dose CT imaging	37
PregGAN: A prognosis prediction model for breast cancer based on conditional generative adversarial networks	37
Regularized multi-task learning with individual-feature-based task correlations for Alzheimer’s cognitive score prediction	36
A neural network framework for immediate temperature prediction of surgical hand-held drilling	36
Effect of pulmonary regurgitation on cardiac functions based on a human bi-ventricle model	36
Disease X epidemic control using a stochastic model and a deterministic approximation: Performance comparison with and without parameter uncertainties	36
Predicting the Risk of Type B Aortic Dissection Using Hemodynamic Parameters in Aortic Arches: A Comparative Study between Healthy and Repaired Aortas	35
S-Net: A novel shallow network for enhanced detail retention in medical image segmentation	35
Quantitative cervical spine injury responses in whiplash loading with a numerical method of natural neural reflex consideration	35
Coronary artery disease severity and location detection using deep-mining-based magnetocardiography pattern features	35
A novel MCF-Net: Multi-level context fusion network for 2D medical image segmentation	35
Self-supervised learning with self-distillation on COVID-19 medical image classification	35
Localizing the seizure onset zone and predicting the surgery outcomes in patients with drug-resistant epilepsy: A new approach based on the causal network	35
Performance and limitations of a supervised deep learning approach for the histopathological Oxford Classification of glomeruli with IgA nephropathy	35
Exploring emotional climate recognition in peer conversations through bispectral features and affect dynamics	35
Automatic registration of dental CT and 3D scanned model using deep split jaw and surface curvature	35
SP-XTIN: A single projection grating-based X-ray tri-contrast imaging network	34
ML3CNet: Non-local means-assisted automatic framework for lung cancer subtypes classification using histopathological images	34
Evaluation of the spline reconstruction technique for preclinical PET imaging	34
Editorial Board	34
Biomechanical analysis of femoral stems in hinged total knee arthroplasty in physiological and osteoporotic bone	34
Towards robust multimodal ultrasound classification for liver tumor diagnosis: A generative approach to modality missingness	34
DARVIC: Dihedral angle-reliant variant impact classifier for functional prediction of missense VUS	34
3D multi-scale residual fully convolutional neural network for segmentation of extremely large-sized kidney tumor	34
Translating medical image to radiological report: Adaptive multilevel multi-attention approach	34
Editorial Board	34
Prediction of lung cancer risk based on age and smoking history	33
Enlarging the thermal coagulation volume during thermochemical ablation with alternating acid-base injection by shortening the injection interval: A computational study	33
MM-CCNB: Essential protein prediction using MAX-MIN strategies and compartment of common neighboring approach	33
Effective active learning in digital pathology: A case study in tumor infiltrating lymphocytes	33
Surgical procedure prediction using medical ontological information	33
A high-fidelity geometric multiscale hemodynamic model for predicting myocardial ischemia	33
Multi-target reconstruction based on subspace decision optimization for bioluminescence tomography	33
Image-based Artificial Intelligence models in the diagnosis and classification of vascular anomalies of the soft tissue in the head and neck	32
Dynamic simulation and analysis of the influence of urethral morphological changes on urodynamics after benign prostatic hyperplasia surgery: A computational fluid dynamics study	32
Considering population variability of electrophysiological models improves the in silico assessment of drug-induced torsadogenic risk	32
A novel endoscopic posterior cervical decompression and interbody fusion technique: Feasibility and biomechanical analysis	32
Editorial Board	32
An end-to-end framework for intima media measurement and atherosclerotic plaque detection in the carotid artery	31
NeuroDM: Decoding and visualizing human brain activity with EEG-guided diffusion model	31
Monte Carlo modeling of hepatic steatosis based on stereology and spatial distribution of fat droplets	31
CAD-RADS scoring of coronary CT angiography with Multi-Axis Vision Transformer: A clinically-inspired deep learning pipeline	31
A joint evaluation method of dynamic spectrum extraction methods for non-invasive blood component measurement based on stability coefficient, data point adoption rate, and smoothness of the spectrum	31
Gait performance in toddlers born preterm: A sensor based quantitative characterization	31
Light scattering imaging modal expansion cytometry for label-free single-cell analysis with deep learning	31

A robust myoelectric pattern recognition framework based on individual motor unit activities against electrode array shifts	31
Assessing ChatGPT's ability to emulate human reviewers in scientific research: A descriptive and qualitative approach	30
Numerical study on optimization of quantitative treatment conditions for skin cancer photothermal therapy considering multiple blood vessels	30
SEMRES - A Triple Security Protected Blockchain Based Medical Record Exchange Structure	30
Neonatal EEG seizure detection using a new signal structural complexity measure based on matching pursuit decomposition with nonstationary dictionary	30
Tailored cancer therapy by magnetic nanoparticle hyperthermia: A virtual scenario simulation method	30
GCW-UNet segmentation of cardiac magnetic resonance images for evaluation of left atrial enlargement	30
An accurate and trustworthy deep learning approach for bladder tumor segmentation with uncertainty estimation	30
Lesion attention guided neural network for contrast-enhanced mammography-based biomarker status prediction in breast cancer	30
Recent advancements and future directions in automatic swallowing analysis via videofluoroscopy: A review	30
Sensitivity analysis of paediatric knee kinematics to the graft surgical parameters during anterior cruciate ligament reconstruction: A sequentially linked neuromusculoskeletal-finite element analysis	30
An agent-based model to assess large-scale COVID-19 vaccination campaigns for the Italian territory: The case study of Lombardy region	29
The role of AI for improved management of breast cancer: Enhanced diagnosis and health disparity mitigation	29
Granger causality test with nonlinear neural-network-based methods: Python package and simulation study	29
MEDUSA©: A novel Python-based software ecosystem to accelerate brain-computer interface and cognitive neuroscience research	29
gACSON software for automated segmentation and morphology analyses of myelinated axons in 3D electron microscopy	29
Displacement voxelization to resolve mesh-image mismatch: Application in deriving dense white matter fiber strains	29
Human-computer interaction on virtual reality-based training system for vascular interventional surgery	29
Parameter quantification for oxygen transport in the human brain	29
Nonlinear dose-response relationship in tDCS-induced brain network synchrony: A resting-state whole-brain model analysis	29
A risk and credibility framework for in silico clinical trials of medical devices	29
mvLognCorrEst: an R package for sampling from multivariate lognormal distributions and estimating correlations from uncomplete correlation matrix	29
Progression of blood-borne viruses through bloodstream: A comparative mathematical study	29
Breathing patterns recognition: A functional data analysis approach	29
A novel CFD-based computed index of microcirculatory resistance (IMR) derived from coronary angiography to assess coronary microcirculation	29
A novel fine-tuning and evaluation methodology for large language models on IoT raw data summaries (LLM-RawDMeth): A joint perspective in diabetes care	29
The synergy of cybernetical intelligence with medical image analysis for deep medicine: A methodological perspective	28
EESCN: A novel spiking neural network method for EEG-based emotion recognition	28
A practical strategy for data assimilation of cerebral intra-aneurysmal flows using a variational method with boundary control of velocity	28
An expert review of the inverse problem in electrocardiographic imaging for the non-invasive identification of atrial fibrillation drivers	28
Noninvasive and fast method of calculation for instantaneous wave-free ratio based on haemodynamics and deep learning	28
A Medical image segmentation model with auto-dynamic convolution and location attention mechanism	28
Rad4XCNN: A new agnostic method for post-hoc global explanation of CNN-derived features by means of Radiomics	28
Automating COVID-19 epidemiological situation reports based on multiple data sources, the Netherlands, 2020 to 2023	28
Altered dynamic joint space in the lateral condyle compartment following medial unicompartmental knee arthroplasty	28
Characterization of mechanical properties of adult chests during pre-hospital manual chest compressions through a simple viscoelastic model	28
From free‐text electronic health records to structured cohorts: Onconum, an innovative methodology for real‐world data mining in breast cancer	28
Effect of a reduced arterial axial pre-stretch ratio during aging on the cardiac output and cerebral blood flow in the healthy elders	28
Assessing the impact of tear direction in coronary artery dissection on thrombosis development: A hemodynamic computational study	28
BAPCP: A comprehensive and user-friendly web tool for identifying biomarkers from protein microarray technologies	28
Theoretical prediction of early afterdepolarization-evoked triggered activity formation initiating ventricular reentrant arrhythmias	27
Chained occurrences of early afterdepolarizations may create a directional triggered activity to initiate reentrant ventricular tachyarrhythmias	27
The effect of CT high-resolution imaging diagnosis based on deep residual network on the pathology of bladder cancer classification and staging	27
Dual-path neural network extracts tumor microenvironment information from whole slide images to predict molecular typing and prognosis of Glioma	27
Multi-event survival analysis through dynamic multi-modal learning for ICU mortality prediction	27
A Physics-Integrated Deep Learning Approach for Patient-Specific Non-Newtonian Blood Viscosity Assessment using PPG	27
Computational simulation of cellular proliferation using a meshless method	27
Artery fragment guided approach for enhancing cerebral aneurysm detection in TOF-MRA imaging	27
Skin lesion classification based on two-modal images using a multi-scale fully-shared fusion network	27
Interpretable epidemic state estimation via rule based modeling	27
4D-Precise: Learning-based 3D motion estimation and high temporal resolution 4DCT reconstruction from treatment 2D+t X-ray projections	26
Virtual diabetic patient with physical activity dynamics	26
BGCSL: An unsupervised framework reveals the underlying structure of large-scale whole-brain functional connectivity networks	26
Associative knowledge graphs for efficient sequence storage and retrieval	26
Shape-aware inference scheme for selective extraction of head-neck arteries on computer tomography angiography images	26
DAX-Net: A dual-branch dual-task adaptive cross-weight feature fusion network for robust multi-class cancer classification in pathology images	26
BaroWavelet: An R-based tool for dynamic baroreflex evaluation through wavelet analysis techniques	26
Symbolic knowledge extraction for explainable nutritional recommenders	26
High-order mesoscale modeling with geometrically conforming gray/white matter interface for traumatic brain injury	26
Developing a reduced order model for pulsatile blood flow simulations using minimal three-dimensional simulation data	26
Influence of adaptive denoising on Diffusion Kurtosis Imaging at 3T and 7T	26
Editorial Board	26
A deep dive into the static force transmission of the human masticatory system and its biomechanical effects on the temporomandibular joint	26
MEMOL: Mixture of experts for multimodal learning through multi-head attention to predict drug toxicity	26
Optimization of thread configuration in dental implants through regulating the mechanical stimuli in neighboring bone	26
Masked hypergraph learning for weakly supervised histopathology whole slide image classification	25
Effects of using different algorithms and fiducial points for the detection of interbeat intervals, and different sampling rates on the assessment of pulse rate variability from photoplethysmography	25
Classification of recurrent major depressive disorder using a residual denoising autoencoder framework: Insights from large-scale multisite fMRI data	25
Precise prediction of multiple anticancer drug efficacy using multi target regression and support vector regression analysis	25
Radiomics feature analysis for survival prediction in multiple myeloma: An automated PET/CT approach	25
Screening chronic myeloid leukemia neutrophils using a novel 3-Dimensional Spectral Gradient Mapping algorithm on hyperspectral images	25
Endoscopic versus laparoscopic bariatric procedures: A computational biomechanical study through a patient-specific approach	25
Real-time estimation of lung deformation from body surface using a general CoordConv CNN	25
Scale resolving simulations of the effect of glottis motion and the laryngeal jet on flow dynamics during respiration	25
Automated quantitative analysis of peri-articular bone microarchitecture in HR-pQCT knee images	25
Monitoring deterioration of knee osteoarthritis using vibration arthrography in daily activities	25
A real-time reconstructed grid method for soft tissue cutting and haptic	25
Robust asynchronous control of ERP-Based brain-Computer interfaces using deep learning	25
Interactive polar diagrams for model comparison	25
Experimental and computational model approach to assess the photothermal effects in transparent nanocrystalline yttria stabilized zirconia cranial implant	25
A Markov Chain methodology for care pathway mapping using health insurance data, a study case on pediatric TBI	25
MigraR: An open-source, R-based application for analysis and quantification of cell migration parameters	25
AutoDPS: An unsupervised diffusion model based method for multiple degradation removal in MRI	24
Lightweight convolution transformer for cross-patient seizure detection in multi-channel EEG signals	24
LivXAI-Net: An explainable AI framework for liver disease diagnosis with IoT-based real-time monitoring support	24
3D-MRI super-resolution reconstruction using multi-modality based on multi-resolution CNN	24
Enhancing multimodal medical image analysis with Slice-Fusion: A novel fusion approach to address modality imbalance	24
Gradient boosted trees with individual explanations: An alternative to logistic regression for viability prediction in the first trimester of pregnancy	24
Developing machine learning models for prediction of mortality in the medical intensive care unit	24
Attentional decoder networks for chest X-ray image recognition on high-resolution features	24
Tumor spheroid elasticity estimation using mechano-microscopy combined with a conditional generative adversarial network	24
Real-time ultrasound shear wave elastography using a local phase gradient	24
PredictMed-epilepsy: A multi-agent based system for epilepsy detection and prediction in neuropediatrics	24
DE-MRI myocardial fibrosis segmentation and classification model based on multi-scale self-supervision and transformer	24
Physics-Informed Graph Neural Networks to solve 1-D equations of blood flow	24