Computer Methods and Programs in Biomedicine

Papers
(The TQCC of Computer Methods and Programs in Biomedicine is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Identifying the patient harms to include in an in silico clinical trial609
CPSS: Fusing consistency regularization and pseudo-labeling techniques for semi-supervised deep cardiovascular disease detection using all unlabeled electrocardiograms334
Real-time soft body dissection simulation with parallelized graph-based shape matching on GPU288
An interactive and realistic phantom for cricothyroidotomy simulation of a patient with obesity through a reusable design using 3D-printing and Arduino238
Editorial Board232
4-dimensional local radial basis function interpolation of large, uniformly spaced datasets214
Dual-modeling computational framework of magnetoelectric core-shell nanoparticles and nanochain for wireless peripheral nerve regeneration210
MSigSeg: An R package for multiple signals segmentation167
Prediction of neoadjuvant therapy response to HER2-positive and triple-negative breast cancer: a multicenter proof-of-concept study163
Finite element analysis of conductive hearing loss caused by fixation and detachment of ligament and tendon in the middle ear140
VesselKnife – software for the analysis of tubular structures in biomedical images127
Unsupervised band selection of medical hyperspectral images guided by data gravitation and weak correlation119
Importance of the enhanced cooling system for more spherical ablation zones: Numerical simulation, ex vivo and in vivo validation112
VOC-DL: Deep learning prediction model for COVID-19 based on VOC virus variants108
Raw photoplethysmogram waveforms versus peak-to-peak intervals for machine learning detection of atrial fibrillation: Does waveform matter?107
TiDE-Net: A time-guided dual-encoder ResUNet for Positron Emission Tomography (PET) image denoising102
Using machine learning models for predicting monthly iPTH levels in hemodialysis patients100
Prediction of the mode of delivery using artificial intelligence algorithms99
Influence of genetic mutations to atria vulnerability to atrial fibrillation: An in-silico 3D human atria study97
Oblique lateral interbody fusion: role of the elastic modulus of the cage material in mechanically induced osteogenesis91
MEFA-Unet: Multi-scale feature extraction and fusion attentional unet for segmenting short process of incus in otologic microsurgical scenarios90
Integrative analysis of RNA modification-related gene PUS7 in diagnosis, prognosis, and tumor microenvironment of hepatocellular carcinoma89
A temporal convolutional network-based approach and a benchmark dataset for colonoscopy video temporal segmentation88
SIMUS3: An open-source simulator for 3-D ultrasound imaging84
Biomechanical analysis of all-polyethylene total knee arthroplasty on periprosthetic tibia using the finite element method82
Unsupervised domain adaptation for nuclei segmentation: Adapting from hematoxylin & eosin stained slides to immunohistochemistry stained slides using a curriculum approach81
Evaluation of deep learning training strategies for the classification of bone marrow cell images81
A cloud-based consultation and collaboration system for radiotherapy: Remote decision support services for community radiotherapy centers79
Modelling lower-limb peripheral arterial disease using clinically available datasets: impact of inflow boundary conditions on hemodynamic indices for restenosis prediction78
Multimodal radiomics based on lesion connectome predicts stroke prognosis75
Temporal convolutional neural network-based feature extraction and asynchronous channel information fusion method for heart abnormality detection in phonocardiograms75
Differential evolution method to find optimal location of a single-element transducer for transcranial focused ultrasound therapy75
CAPNet: Context attention pyramid network for computer-aided detection of microcalcification clusters in digital breast tomosynthesis75
IODeep: An IOD for the introduction of deep learning in the DICOM standard74
A Graph-guided Hybrid Regularization Method For Bioluminescence Tomography74
MBGA-Net: A multi-branch graph adaptive network for individualized motor imagery EEG classification73
A study on brain tumor dynamics in two-dimensional irregular domain with variable-order time-fractional derivative71
Modelling of cardiac biventricular electromechanics with coronary blood flow to investigate the influence of coronary arterial motion on coronary haemodynamic70
A real-time computer-aided diagnosis method for hydatidiform mole recognition using deep neural network69
CUAMT: A MRI semi-supervised medical image segmentation framework based on contextual information and mixed uncertainty69
The impact of small movements with dual lumen cannulae during venovenous extracorporeal membrane oxygenation: A computational fluid dynamics analysis68
Cuffless blood pressure estimation using chaotic features of photoplethysmograms and parallel convolutional neural network65
From local counterfactuals to global feature importance: efficient, robust, and model-agnostic explanations for brain connectivity networks63
Detecting optimal biomarkers in ovarian cancer cells from high-dimensional mRNA expression data using machine learning63
Optimal machine learning methods for prediction of high-flow nasal cannula outcomes using image features from electrical impedance tomography62
An automatic pipeline for atlas-based fetal and neonatal brain segmentation and analysis62
SC-Net: Symmetrical conical network for colorectal pathology image segmentation60
FMCW radar based high-precision gridless non-contact vital signs monitoring for Internet of Medical Things60
Lung nodule classification using radiomics model trained on degraded SDCT images60
An ensemble classifier for emotion classification from EEG and GSR signals for autism detection60
CTGAN-driven synthetic data generation: A multidisciplinary, expert-guided approach (TIMA)59
Light&fast generative adversarial network for high-fidelity CT image synthesis of liver tumor59
Fear of falling in community-dwelling older adults: What their gait acceleration pattern reveals57
Computer-aided detection and segmentation of malignant melanoma lesions on whole-body 1856
Medical image super-resolution reconstruction algorithms based on deep learning: A survey56
A novel MCF-Net: Multi-level context fusion network for 2D medical image segmentation56
KUB-UNet: Segmentation of Organs of Urinary System from a KUB X-ray Image55
S-Net: A novel shallow network for enhanced detail retention in medical image segmentation55
Health classification of Meibomian gland images using keratography 5M based on AlexNet model54
Simulation-driven optimization of insulin therapy profiles in a commercial hybrid closed-loop system54
A computational method to predict cerebral perfusion flow after endovascular treatment based on invasive pressure and resistance54
A myocardial reorientation method based on feature point detection for quantitative analysis of PET myocardial perfusion imaging54
Disease X epidemic control using a stochastic model and a deterministic approximation: Performance comparison with and without parameter uncertainties52
Multi-scale dual-channel feature embedding decoder for biomedical image segmentation52
Artificial intelligence model for tumoral clinical decision support systems52
Reallocation of cutaneous and global blood circulation during sauna bathing through a closed-loop model51
FM-Net: Deep Learning Network for the Fundamental Matrix Estimation from Biplanar Radiographs50
Quantitative cervical spine injury responses in whiplash loading with a numerical method of natural neural reflex consideration50
A numerical simulation study of soft tissue resection for low-damage precision cancer surgery50
PregGAN: A prognosis prediction model for breast cancer based on conditional generative adversarial networks49
Missing data imputation using utility-based regression and sampling approaches49
Extension of physical activity recognition with 3D CNN using encrypted multiple sensory data to federated learning based on multi-key homomorphic encryption49
Integrating prior knowledge with deep learning for optimized quality control in corneal images: A multicenter study49
In-silico neuro musculoskeletal model reproduces the movement types obtained by spinal micro stimulation49
Multi-scale simulation of red blood cell trauma in large-scale high-shear flows after Norwood operation48
Multi-electrode catheter PFA: Computational modeling and in vivo validation of lesion dynamics under energy-dose variants48
TransAnno-Net: A Deep Learning Framework for Accurate Cell Type Annotation of Mouse Lung Tissue Using Self-supervised Pretraining48
Data-driven sleep structure deciphering based on cardiorespiratory signals48
Predicting the Risk of Type B Aortic Dissection Using Hemodynamic Parameters in Aortic Arches: A Comparative Study between Healthy and Repaired Aortas47
Editorial Board45
PyMIC: A deep learning toolkit for annotation-efficient medical image segmentation45
Editorial Board45
Self-supervised learning with self-distillation on COVID-19 medical image classification45
Retinex-qDPC: Automatic background-rectified quantitative differential phase contrast imaging45
Effect of pulmonary regurgitation on cardiac functions based on a human bi-ventricle model44
A probabilistic generative model to discover the treatments of coexisting diseases with missing data44
MRCON-Net: Multiscale reweighted convolutional coding neural network for low-dose CT imaging44
Phantom study of an in-house amplitude-gating respiratory method with silicon photomultiplier technology positron emission tomography/computed tomography44
TGMIL: A hybrid multi-instance learning model based on the Transformer and the Graph Attention Network for whole-slide images classification of renal cell carcinoma43
United multi-task learning for abdominal contrast-enhanced CT synthesis through joint deformable registration43
Localizing the seizure onset zone and predicting the surgery outcomes in patients with drug-resistant epilepsy: A new approach based on the causal network42
Molecular dynamics simulation of hyaluronic acid hydrogels: Effect of water content on mechanical and tribological properties42
An improved binary particle swarm optimization algorithm for clinical cancer biomarker identification in microarray data42
Translating medical image to radiological report: Adaptive multilevel multi-attention approach42
CRMIPred: Identifying the spatial interactions among cis-regulatory modules via considering their cross-attended epigenetic profiles41
A multi-task learning model with reinforcement optimization for ASD comorbidity discrimination41
Prediction of iliac limb occlusion after endovascular aneurysm repair for abdominal aortic aneurysm by anatomical and near-wall hemodynamic characteristics combining numerical simulation and in vitro 41
SMD-YOLO: An efficient and lightweight detection method for mask wearing status during the COVID-19 pandemic41
A multiconsistent computational methodology to resolve a diffusive epidemiological system with effects of migration, vaccination and quarantine41
Coronary artery disease severity and location detection using deep-mining-based magnetocardiography pattern features41
Recurrence quantification analysis of rs-fMRI data: A method to detect subtle changes in the TgF344-AD rat model40
Phys-DAT: A physiologically-based pharmacokinetic model for unraveling the dissolution, transit and absorption processes using PhysPK®39
A neural network framework for immediate temperature prediction of surgical hand-held drilling39
Improving convolutional neural network learning based on a hierarchical bezier generative model for stenosis detection in X-ray images39
A simple agent-based hybrid model to simulate the biophysics of glioblastoma multiforme cells and the concomitant evolution of the oxygen field39
SFTNet: A microexpression-based method for depression detection39
Regularized multi-task learning with individual-feature-based task correlations for Alzheimer’s cognitive score prediction39
Corrigendum to “Generation of post-meal insulin correction boluses in type 1 diabetes simulation models for in-silico clinical trials: More realistic scenarios obtained using a decision tree approach”38
Performance and limitations of a supervised deep learning approach for the histopathological Oxford Classification of glomeruli with IgA nephropathy38
Corrigendum to “Segmentation of skin layers on HFUS images using the attention mechanism”, [Computer Methods and Programs in Biomedicine, 263 (2025) 108668]37
Predicting 6-minute walking test outcomes in patients with chronic obstructive pulmonary disease without physical performance measures37
Multicentric intelligent cardiotocography signal interpretation using deep semi-supervised domain adaptation via minimax entropy and domain invariance37
Dynamic elastic modulus assessment of the early degeneration model of an intervertebral disc in cynomolgus monkeys with one strike loading37
Digital signal extraction approach for cardiotocography image37
Haemosync: A synchronisation algorithm for multimodal haemodynamic signals36
Automatic registration of dental CT and 3D scanned model using deep split jaw and surface curvature36
Modified Theoretical Model Predicts Radial Support Capacity of Polymer Braided Stents36
Corticosteroid sensitivity detection in sepsis patients using a personalized data mining approach: A clinical investigation36
Facial expressions to identify post-stroke: A pilot study36
A new computational pipeline for multicompartment modeling of liver perfusion36
Evaluation of the linear and nonlinear classifiers for distinguishing between healthy subjects and patients with valvular heart diseases based on electrocardiograms, seismocardiograms, and gyrocardiog35
Editorial Board35
gACSON software for automated segmentation and morphology analyses of myelinated axons in 3D electron microscopy35
Rad4XCNN: A new agnostic method for post-hoc global explanation of CNN-derived features by means of Radiomics35
Exploring emotional climate recognition in peer conversations through bispectral features and affect dynamics35
DARVIC: Dihedral angle-reliant variant impact classifier for functional prediction of missense VUS35
Editorial Board35
Editorial Board35
ML3CNet: Non-local means-assisted automatic framework for lung cancer subtypes classification using histopathological images35
SP-XTIN: A single projection grating-based X-ray tri-contrast imaging network35
An accurate and trustworthy deep learning approach for bladder tumor segmentation with uncertainty estimation35
Light scattering imaging modal expansion cytometry for label-free single-cell analysis with deep learning35
Lesion attention guided neural network for contrast-enhanced mammography-based biomarker status prediction in breast cancer34
Multi-target reconstruction based on subspace decision optimization for bioluminescence tomography34
Tailored cancer therapy by magnetic nanoparticle hyperthermia: A virtual scenario simulation method34
A novel endoscopic posterior cervical decompression and interbody fusion technique: Feasibility and biomechanical analysis34
Parameter quantification for oxygen transport in the human brain34
MEDUSA©: A novel Python-based software ecosystem to accelerate brain-computer interface and cognitive neuroscience research34
A joint evaluation method of dynamic spectrum extraction methods for non-invasive blood component measurement based on stability coefficient, data point adoption rate, and smoothness of the spectrum34
Automatic segmentation and CT-based deep learning radiomics nomogram for predicting overall survival in patients with small cell lung cancer: A multicenter cohort study34
Enlarging the thermal coagulation volume during thermochemical ablation with alternating acid-base injection by shortening the injection interval: A computational study34
Progression of blood-borne viruses through bloodstream: A comparative mathematical study34
Human-computer interaction on virtual reality-based training system for vascular interventional surgery33
EESCN: A novel spiking neural network method for EEG-based emotion recognition33
Image-based Artificial Intelligence models in the diagnosis and classification of vascular anomalies of the soft tissue in the head and neck33
Dynamic simulation and analysis of the influence of urethral morphological changes on urodynamics after benign prostatic hyperplasia surgery: A computational fluid dynamics study33
Neonatal EEG seizure detection using a new signal structural complexity measure based on matching pursuit decomposition with nonstationary dictionary33
Effective active learning in digital pathology: A case study in tumor infiltrating lymphocytes33
Considering population variability of electrophysiological models improves the in silico assessment of drug-induced torsadogenic risk33
Sensitivity analysis of paediatric knee kinematics to the graft surgical parameters during anterior cruciate ligament reconstruction: A sequentially linked neuromusculoskeletal-finite element analysis33
MM-CCNB: Essential protein prediction using MAX-MIN strategies and compartment of common neighboring approach33
A novel CFD-based computed index of microcirculatory resistance (IMR) derived from coronary angiography to assess coronary microcirculation33
Numerical study on optimization of quantitative treatment conditions for skin cancer photothermal therapy considering multiple blood vessels33
An agent-based model to assess large-scale COVID-19 vaccination campaigns for the Italian territory: The case study of Lombardy region33
From free‐text electronic health records to structured cohorts: Onconum, an innovative methodology for real‐world data mining in breast cancer33
GCW-UNet segmentation of cardiac magnetic resonance images for evaluation of left atrial enlargement33
A robust myoelectric pattern recognition framework based on individual motor unit activities against electrode array shifts33
Robust prediction of parameterized cardiovascular hemodynamics using deep operator networks with time normalization32
mvLognCorrEst: an R package for sampling from multivariate lognormal distributions and estimating correlations from uncomplete correlation matrix32
NeuroDM: Decoding and visualizing human brain activity with EEG-guided diffusion model32
Nonlinear dose-response relationship in tDCS-induced brain network synchrony: A resting-state whole-brain model analysis32
Assessing ChatGPT's ability to emulate human reviewers in scientific research: A descriptive and qualitative approach32
Towards robust multimodal ultrasound classification for liver tumor diagnosis: A generative approach to modality missingness32
Gait performance in toddlers born preterm: A sensor based quantitative characterization32
CAD-RADS scoring of coronary CT angiography with Multi-Axis Vision Transformer: A clinically-inspired deep learning pipeline32
A novel fine-tuning and evaluation methodology for large language models on IoT raw data summaries (LLM-RawDMeth): A joint perspective in diabetes care31
A practical strategy for data assimilation of cerebral intra-aneurysmal flows using a variational method with boundary control of velocity31
A Multi-physics model of flow from coronary angiography: Insights to microvascular function31
A Medical image segmentation model with auto-dynamic convolution and location attention mechanism31
Characterization of mechanical properties of adult chests during pre-hospital manual chest compressions through a simple viscoelastic model31
Integrating multimodal data and deep learning for functional assessment and rehabilitation prediction after cerebral hemorrhage31
Monte Carlo modeling of hepatic steatosis based on stereology and spatial distribution of fat droplets31
PySERA: Open-Source Standardized Python Library for Automated, Scalable, and Reproducible Handcrafted and Deep Radiomics31
A risk and credibility framework for in silico clinical trials of medical devices31
The role of AI for improved management of breast cancer: Enhanced diagnosis and health disparity mitigation31
Automating COVID-19 epidemiological situation reports based on multiple data sources, the Netherlands, 2020 to 202330
Recent advancements and future directions in automatic swallowing analysis via videofluoroscopy: A review30
A high-fidelity geometric multiscale hemodynamic model for predicting myocardial ischemia30
Effect of a reduced arterial axial pre-stretch ratio during aging on the cardiac output and cerebral blood flow in the healthy elders30
AutoDPS: An unsupervised diffusion model based method for multiple degradation removal in MRI30
Surgical procedure prediction using medical ontological information30
Screening chronic myeloid leukemia neutrophils using a novel 3-Dimensional Spectral Gradient Mapping algorithm on hyperspectral images30
Experimental and computational model approach to assess the photothermal effects in transparent nanocrystalline yttria stabilized zirconia cranial implant30
The synergy of cybernetical intelligence with medical image analysis for deep medicine: A methodological perspective30
An end-to-end framework for intima media measurement and atherosclerotic plaque detection in the carotid artery30
Chained occurrences of early afterdepolarizations may create a directional triggered activity to initiate reentrant ventricular tachyarrhythmias29
BGCSL: An unsupervised framework reveals the underlying structure of large-scale whole-brain functional connectivity networks29
A SAS macro for multilevel Cosinor analysis29
Shape-aware inference scheme for selective extraction of head-neck arteries on computer tomography angiography images29
Theoretical prediction of early afterdepolarization-evoked triggered activity formation initiating ventricular reentrant arrhythmias29
Physics-Informed Graph Neural Networks to solve 1-D equations of blood flow29
Influence of adaptive denoising on Diffusion Kurtosis Imaging at 3T and 7T29
Classification of recurrent major depressive disorder using a residual denoising autoencoder framework: Insights from large-scale multisite fMRI data29
BAPCP: A comprehensive and user-friendly web tool for identifying biomarkers from protein microarray technologies29
A deep dive into the static force transmission of the human masticatory system and its biomechanical effects on the temporomandibular joint29
AERMNet: Attention-enhanced relational memory network for medical image report generation29
BaroWavelet: An R-based tool for dynamic baroreflex evaluation through wavelet analysis techniques29
Altered dynamic joint space in the lateral condyle compartment following medial unicompartmental knee arthroplasty28
Real-time estimation of lung deformation from body surface using a general CoordConv CNN28
Interactive polar diagrams for model comparison28
Precise prediction of multiple anticancer drug efficacy using multi target regression and support vector regression analysis28
An expert review of the inverse problem in electrocardiographic imaging for the non-invasive identification of atrial fibrillation drivers28
Towards open-set myoelectric gesture recognition via dual-perspective inconsistency learning28
DE-MRI myocardial fibrosis segmentation and classification model based on multi-scale self-supervision and transformer28
A real-time reconstructed grid method for soft tissue cutting and haptic28
Dual center validation of deep learning for automated multi-label segmentation of thoracic anatomy in bedside chest radiographs28
Patient-specific fluid-structure interaction modeling of cerebral aneurysm: influence of wall compliance, tissue prestress, and blood rheology28
4D-Precise: Learning-based 3D motion estimation and high temporal resolution 4DCT reconstruction from treatment 2D+t X-ray projections28
Noninvasive and fast method of calculation for instantaneous wave-free ratio based on haemodynamics and deep learning28
Optimization of thread configuration in dental implants through regulating the mechanical stimuli in neighboring bone28
High-order mesoscale modeling with geometrically conforming gray/white matter interface for traumatic brain injury28
Endoscopic versus laparoscopic bariatric procedures: A computational biomechanical study through a patient-specific approach28
Hemolysis performance investigation of aortic valve pump based on computational fluid dynamics and entropy production theory27
Developing a reduced order model for pulsatile blood flow simulations using minimal three-dimensional simulation data27
Enhancing multimodal medical image analysis with Slice-Fusion: A novel fusion approach to address modality imbalance27
Interpretable epidemic state estimation via rule based modeling27
Skin lesion segmentation using two-phase cross-domain transfer learning framework27
Symbolic knowledge extraction for explainable nutritional recommenders27
Scale resolving simulations of the effect of glottis motion and the laryngeal jet on flow dynamics during respiration27
Radiomics feature analysis for survival prediction in multiple myeloma: An automated PET/CT approach27
PredictMed-epilepsy: A multi-agent based system for epilepsy detection and prediction in neuropediatrics27
Tumor spheroid elasticity estimation using mechano-microscopy combined with a conditional generative adversarial network26
Masked hypergraph learning for weakly supervised histopathology whole slide image classification26
MEMOL: Mixture of experts for multimodal learning through multi-head attention to predict drug toxicity26
DAX-Net: A dual-branch dual-task adaptive cross-weight feature fusion network for robust multi-class cancer classification in pathology images26
Multi-event survival analysis through dynamic multi-modal learning for ICU mortality prediction26
CellViT++: Energy-efficient and adaptive cell segmentation and classification using foundation models26
Computer-aided diagnostic system for hypertensive retinopathy: A review26
A simple EEG-based tool to guide therapeutic hypothermia decisions in neonatal hypoxic-ischemic encephalopathy26
Computational simulation of cellular proliferation using a meshless method26
Real-time ultrasound shear wave elastography using a local phase gradient26
Cross-modal alignment and contrastive learning for enhanced cancer survival prediction26
Inhalation exposure and particle deposition across 16 nonhuman primate airway models using computational fluid–particle dynamics for allometric extrapolation26
3D-MRI super-resolution reconstruction using multi-modality based on multi-resolution CNN26
LivXAI-Net: An explainable AI framework for liver disease diagnosis with IoT-based real-time monitoring support26
A Markov Chain methodology for care pathway mapping using health insurance data, a study case on pediatric TBI26
Classification of mindfulness experiences from gamma-band effective connectivity: Application of machine-learning algorithms on resting, breathing, and body scan25
The impact of arterial cannula direction in central venoarterial extracorporeal membrane oxygenation on aortic hemodynamic characteristics under various perfusion conditions25
Articulating target-mining techniques to disinter Alzheimer's specific targets for drug repurposing25
Dual-path neural network extracts tumor microenvironment information from whole slide images to predict molecular typing and prognosis of Glioma25
Bioinformatic assay reveal the potential mechanism of Guizhi-Shaoyao-Zhimu decoction against rheumatoid arthritis and mild-to-moderate COVID-1925
A multi-task fusion model based on a residual–Multi-layer perceptron network for mammographic breast cancer screening25
Automatic prostate and peri-prostatic fat segmentation based on pyramid mechanism fusion network for T2-weighted MRI25
Attentional decoder networks for chest X-ray image recognition on high-resolution features25
Skin lesion classification based on two-modal images using a multi-scale fully-shared fusion network25
Gluclas: A software for computer-aided modulation of glucose infusion in glucose clamp experiments25
A deep sift convolutional neural networks for total brain volume estimation from 3D ultrasound images25
Harnessing machine learning models for non-invasive pre-diabetes screening in children and adolescents25
A Physics-Integrated Deep Learning Approach for Patient-Specific Non-Newtonian Blood Viscosity Assessment using PPG25
MemBrain: A deep learning-aided pipeline for detection of membrane proteins in Cryo-electron tomograms25
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