OOIR: Observatory of International Research

Papers

(The H4-Index of Advanced Drug Delivery Reviews is 85. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Editorial board members	960
Drug delivery for metabolism targeted cancer immunotherapy	345
Recent advances in endocrine organoids for therapeutic application	295
Emerging strategies to bypass transplant rejection via biomaterial-assisted immunoengineering: Insights from islets and beyond	264
Cell membrane-coated nanoparticles for targeting carcinogenic bacteria	241
Long-acting inhaled medicines: Present and future	223
Design, development and clinical translation of CriPec®-based core-crosslinked polymeric micelles	216
Covalent chemistry in targeted protein degradation	212
Luminescent quantum dots: Synthesis, optical properties, bioimaging and toxicity	211
Nanoparticle-neutrophils interactions for autoimmune regulation	210
Polymer-based drug delivery systems under investigation for enzyme replacement and other therapies of lysosomal storage disorders	210
Progress on the pathological tissue microenvironment barrier-modulated nanomedicine	196
Bacterially mediated drug delivery and therapeutics: Strategies and advancements	189
MIDD in Japan– Implementations, challenges and opportunities	188
Deciphering albumin-directed drug delivery by imaging	184
Liposomal formulations for treating lysosomal storage disorders	181
Gene editing strategies to treat lysosomal disorders: The example of mucopolysaccharidoses	178
Emerging antibiotic alternatives: From antimicrobial peptides to bacteriophage therapies	175
Penetration and translocation of functional inorganic nanomaterials into biological barriers	173
Genome-scale metabolic modelling in antimicrobial pharmacology: Present and future	167
Opportunities and challenges in delivering biologics for Alzheimer’s disease by low-intensity ultrasound	166
Integrating microneedles and sensing strategies for diagnostic and monitoring applications: The state of the art	164
Models to study basic and applied aspects of lysosomal storage disorders	163
Leveraging the neurosurgical operating room for therapeutic development in NeuroOncology	159
In vitro models of the interplay between glioblastoma and blood–brain barrier for stratifying drug efficacy	157

Editorial Board	153
Protein encapsulation of nanocatalysts: A feasible approach to facilitate catalytic theranostics	146
Nanoparticles-mediated ion channels manipulation: From their membrane interactions to bioapplications	145
Exosome- and extracellular vesicle-based approaches for the treatment of lysosomal storage disorders	143
Synthetic biology-guided design and biosynthesis of protein polymers for delivery	139
Editorial/Preface	138
Targeting microbiome, drug metabolism, and drug delivery in oncology	137
Emerging Voices in Drug Delivery – Harnessing and Modulating Complex Biological Systems (Issue 2)	136
3D printing of drug delivery systems enhanced with micro/nano-technology	132
Drug delivery using gold nanoparticles	128
Activatable fluorescent probes for real-time imaging-guided tumor therapy	126
Strategies to develop polymeric microneedles for controlled drug release	126
From cells to subcellular organelles: Next-generation cancer therapy based on peptide self-assembly	120
Activatable dual-functional molecular agents for imaging-guided cancer therapy	118
Hydrogen sulfide in cancer therapy: Intelligent delivery platforms and synergistic therapeutic paradigms	118
Biomarker and therapeutic potential of peripheral extracellular vesicles in Alzheimer’s disease	117
iPSC-derived T cells and macrophages: Manufacturing and next-generation application approaches	116
Solid implantable devices for sustained drug delivery	115
RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer	114
In situ cellular hitchhiking of nanoparticles for drug delivery	112
Red to near-infrared carbon dots: synthesis, cellular interactions, drug loading, and therapeutic applications	110
Quality by Computational Design: Harnessing AI to Advance Rational Drug Development	109
Pulmonary delivery nanomedicines towards circumventing physiological barriers: Strategies and characterization approaches	109
Small data, big challenges: Machine- and deep-learning strategies for data-limited drug discovery	106
Novel strategies for modulating the gut microbiome for cancer therapy	106
Therapeutic gases as emerging treatments for oral diseases	105
Biopharmaceutical drug delivery and phototherapy using protein crystals	105
Engineering complexity in human tissue models of cancer	104
Advances in photoactivated carbon-based nanostructured materials for targeted cancer therapy	104
Lysosomal therapies and drug delivery strategies: An overview	102
Technology for Nucleic Acid Delivery in the Treatment of Hematological Malignancies	102
Engineering bacterial membrane nanovesicles for improved therapies in infectious diseases and cancer	101
Tumor microenvironment subtyping in pancreatic ductal adenocarcinoma: New avenues for personalized therapeutic strategies	100
Hurdles in translating science from lab to market in delivery systems for Cosmetics: An industrial perspective	100
Tumour extravasation of nanomedicine: The EPR and alternative pathways	100
Micro-patterned cell populations as advanced pharmaceutical drugs with precise functional control	98
Novel drug delivery systems for the management of dry eye	98
Convection-enhanced delivery for brain malignancies: Technical parameters, formulation strategies and clinical perspectives	97
Overcoming therapy resistance in pancreatic cancer: challenges and emerging strategies	97
Nanobodies: Robust miniprotein binders in biomedicine	95
Miniaturized therapeutic systems for ultrasound-modulated drug delivery to the central and peripheral nervous system	94
Antibody-drug conjugates as multimodal therapies against hard-to-treat cancers	94
Soft nano and microstructures for the photomodulation of cellular signaling and behavior	93
Matrix-integrated microfluidic tumor models for evaluating drug delivery systems and pre-clinical testing	92
Nanosensitizer-mediated unique dynamic therapy tactics for effective inhibition of deep tumors	92
Unignored intracellular journey and biomedical applications of extracellular vesicles	92
Light sheet fluorescence microscopy for monitoring drug delivery: Unlocking the developmental phases of embryos	91
Model-informed precision dosing: State of the art and future perspectives	90
Emerging drug delivery systems with traditional routes – A roadmap to chronic inflammatory diseases	90
Fit and forget: The future of dental implant therapy via nanotechnology	90

Lipid nanoparticles for targeted delivery of anticancer therapeutics: Recent advances in development of siRNA and lipoprotein-mimicking nanocarriers	90
Editorial Board	89
Preface: Image-assisted organoid research and application	89
Nanoparticle-based immunotherapeutics: From the properties of nanocores to the differential effects of administration routes	88
Editorial Board	88
Oral nanomedicine biointeractions in the gastrointestinal tract in health and disease	87
MicroRNA-targeting nanomedicines for the treatment of intervertebral disc degeneration	87
Design of disintegrable nanoassemblies to release multiple small-sized nanoparticles	86
Editorial board members	86
Molecularly targeted nanomedicine enabled by inorganic nanoparticles for atherosclerosis diagnosis and treatment	85
Corrigendum to “Editorial: Advanced strategies to bridge the gap between inflammation and tissue regeneration” [Adv. Drug Deliv. Rev. 209 (2024) 115328]	85
Design principles for construction of DNA-based nanostructures	85
Engineering tissue patterning in human stem cell-based embryo models	85
Editorial board members	85