Immunobiology

Article	Citations
Editorial Board	51
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130 Low Gene Copy Numbers (GCN) of complement C4 and C4A deficiency are highly significant genetic risk factors for idiopathic inflammatory myopathies and its major subgroups	32
84 Inhibition of SARS-CoV-2 spike interaction with angiotensin converting enzyme-2 (ACE2) by specific antibodies is enhanced by complement, determined with a novel flow cytometry assay	31
164 Role of nutraceuticals in ameliorating inflammation in Alzheimer[StQuote]s disease	28
146 A transcriptome array-based approach to link SGLT-2 and tubulointerstitial synthesis of complement C5 in IgA nephropathy	26
Chronic NOD2 stimulation by MDP confers protection against parthanatos through M2b macrophage polarization in RAW264.7 cells	24
165 IQGAP1 deficiency promotes complement activation on podocytes: New insights into the pathogenesis of kidney complement-mediated disease	24
Toll-like receptor upregulation in liver and peripheral blood mononuclear cells of patients with amoebic liver abscess	22
Inhibiting the alternative pathway of complement by reducing systemic complement factor B: Randomized, double-blind, placebo-controlled phase 1 studies with Sefaxersen	22
Predictive value and mechanism of lncRNA MANCR for pediatric severe pneumonia via miR-20a-5p / MAPK1 axis	22
CVB3 regulates Treg cell pyroptosis through the lncRNA XIST/miR-195-5p/caspase-1 molecular axis	20
Granulomatous inflammation and hypogammaglobulinemia: Clinical conundrum of familial hemophagocytic lymphohistiocytosis type 5	18
Characterization of the impact of immune checkpoint inhibitors on platelet activation and aggregation	18
Clostridium butyricum attenuates LPS-induced myocardial injury in septic mice by modulating CD4 + CD25 + FOXP3 + Treg	17
STING modulates HBV-related acute-on-chronic liver failure by mediating autophagy and macrophage polarization	17
LncRNA OGFRP1 promotes angiogenesis and epithelial-mesenchymal transition in colorectal cancer cells through miR-423-5p/CTCF axis	17
Maternal stress increases risk of allergic lung inflammation in adult mice	16
Reduced susceptibility to COVID-19 associated with ABO blood group and pre-existing anti-A and anti-B antibodies	15
Acquired decrease of the C3b/C4b receptor (CR1, CD35) and increased C4d deposits on erythrocytes from ICU COVID-19 patients	15
Selective downregulation of natural killer activating receptors on NK cells and upregulation of PD-1 expression on T cells in children with severe and/or recurrent Herpes simplex virus infections	15
Complement activation and kidney transplantation; a complex relationship	14
CARD11 dominant negative mutation leads to altered human Natural Killer cell homeostasis	14
The safety and efficacy of tumor necrosis factor-alpha inhibitor on pregnancy outcomes in patients with unexplained recurrent miscarriage	14
PD-L1 and PD-L2 immune checkpoint protein induction by type III interferon in non-small cell lung cancer cells	14

Immune activating and inhibiting effects of calcitriol on γδ T cells and NK cells	14
Down-regulation of MLLT1 super elongation complex subunit impairs the anti-tumor activity of natural killer cells in esophageal cancer	13
Deletion of mesencephalic astrocyte-derived neurotrophic factor delays and damages the development of white pulp in spleen	13
PLEKHA4 promotes glioblastoma progression through apoptosis inhibition, tumor cell migration, and macrophage infiltration	13
Alterations in Helios+ T cell subsets in peripheral blood of early-stage lung adenocarcinoma patients: Implications for early diagnosis	13
Multifocal thrombosis with peripheral gangrene in a young boy: Mycoplasma infection triggered cold agglutinin disease	13
225 Single cell analysis (SCA) of PBMCs for a patient with congenital non-functional CD59	12
Amniotic fluid stem cell attenuated necrotizing enterocolitis progression by promoting Rspo3/AMPKα axis	12
Highly dampened HIV-specific cytolytic effector T cell responses define viremic non-progression	12
27 Elucidating the molecular mechanisms mediating the tumor suppressive actions of complement inhibitor CSMD1 in gliomas	12
The significance of antiglobulin (Coombs) test reactivity in patients with COVID-19	12
170 Increased complement activation in recipients is associated with chronic rejection after lung transplantation	11
93 Modeling complement activation on human glomerular microvascular endothelial cells	11
104 Targeting terminal pathway in brain reduces complement activation and synapse loss in a mouse model of dementia	11
86 Assessing Complement Factor B Function: A Comparison of Hemolytic and Immunofixation Electrophoresis-based Assays	11
147 Antibodies against Streptococcus pneumoniae pneumolysin correlate with modified HDL levels and complement activation markers in peripheral arterial disease patients	10
109 Investigation of complement-related integrin receptors using a screening platform and newly developed tool compounds	10
99 Targeted complement inhibition using engineered bispecific antibodies that bind local antigens and endogenous complement regulators as a novel therapeutic approach	10
59 DNA-templated antibody complexes provide insights into the geometric requirements of human complement activation	9
49 The binding and kinetics of normal versus pathogenic C3 convertase autoantibodies	9
81 Clinical and histologic correlations in C3 glomerulopathy	9
74 αβ T cells and complement meet again: TCR crosstalk with surface complement regulators	9
220 CD59-/- is protected from glucose intolerance, insulin resistance and fatty liver disease	9
210 Complement activation in patients with ANCA-associated vasculitis – focusing on complement activation markers in remission	9
237 Despite altered immune compartments and increased complement consumption, heterozygous C3 gain-of-function mice do not develop atypical haemolytic syndrome following exposure to various inflammato	9
232 Effect of IL-1ß and C3a on complement expression and secretion on human osteoarthritic chondrocytes	9
230 Interaction of factor H and factor H-related proteins with S and N proteins of SARS-CoV-2	8
20 The C5aR2 pathway as a potential novel checkpoint for B cell activation and differentiation	8
47 Plasma factor D cross-sectionally associates with low-grade inflammation, endothelial dysfunction and cardiovascular disease, but not with intima-media thickness or ankle-brachial index: The Maastr	8
37 Intracellular complement in atypical hemolytic-uremic syndrome	8
123 The temporal role of complement in severe trauma and hemorrhagic shock	8
242 Does C1q modulate myelin sheath development in zebrafish?	8
138 Escherichia coli-induced platelet aggregation in human whole blood is partly dependent on complement C3b	8
90 Complement activation during hypoxia-reoxygenation in human kidney epithelial cells	8
201 Leptospira interrogans leptolysin displays proteolytic activity against complement proteins	8
199 A role for complement in sickle cell disease	8
171 The dominant form of the C1 inhibitor R444C variant causing type II hereditary angioedema is its covalent adduct with serum albumin explaining elevated levels	7
185 CPV-104, an improved recombinant variant of human complement factor H produced in moss, is a prime candidate for clinical application in complement mediated diseases	7
71 Acinetobacter baumannii clinical isolates evade complement-mediated lysis by inhibiting the complement cascade and improperly depositing MAC	7
41 Assessing the feasibility of genetically modified porcine red blood cells as an alternative to human red blood cells for transfusion	7
63 Heme-induced complement activation in invasive aspergillosis	7
33 C5 cleavage inhibition combined with C3 convertase targeting protects from disease development in a preclinical model of autoimmune skin disease	7
The involvement of oxidative stress and the TLR4/NF-κB/NLRP3 pathway in acute lung injury induced by high-altitude hypoxia	6
23 Study of complement modulation by reactive oxygen species: Revision of existing in vitro data	6
Deregulated phenotype of autoreactive Th17 and Treg clone cells in pemphigus vulgaris after in-vitro treatment with desmoglein antigen (Dsg-3)	6
The role of NFAT2/miR-20a-5p signaling pathway in the regulation of CD8+ naïve T cells activation and differentiation	6
ERAP1 binds peptide C-termini of different sequences and/or lengths by a common recognition mechanism	6
Preferential production and secretion of the complement regulator factor H-like protein 1 (FHL-1) by human myeloid cells	6
MiR-183-5p overexpression in bone mesenchymal stem cell-derived exosomes protects against myocardial ischemia/reperfusion injury by targeting FOXO1	6
Transcription suppression of GABARAP mediated by lncRNA XIST-EZH2 interaction triggers caspase-11-dependent inflammatory injury in ulcerative colitis	6

Adenosine receptor activation promotes macrophage class switching from LPS-induced acute inflammatory M1 to anti-inflammatory M2 phenotype	6
Novel evaluation indicators of MOG35∼55 induced experimental autoimmune encephalomyelitis in C57BL/6J mice	6
IgD ligation allows peritoneal cavity B cell proliferation	6
TLR-2 agonist Pam3CSK4 has no therapeutic effect on visceral leishmaniasis in BALB/c mice and may enhance the pathogenesis of the disease	6
Opportunistic pneumonia caused by E. cuniculi in mice immunosuppressed with cyclophosphamide	6
Induction of CIITA by IFN-γ in macrophages involves STAT1 activation by JAK and JNK	6
Non-coding RNA network associated with obesity and rheumatoid arthritis	6
Ubiquitin-specific protease 34 in macrophages limits CD8 T cell-mediated onset of vitiligo in mice	6
RNA-Seq and ATAC-Seq analyses reveal a global transcriptional and chromatin accessibility profiling of γδ T17 differentiation from mouse spleen	6
Exploring the relationship between pyroptosis, infiltrating immune cells and Kawasaki disease with resistance to intravenous immunoglobulin (IVIG) via bioinformatic analysis	6
NK-92 cells change their phenotype and function when cocultured with IL-15, IL-18 and trophoblast cells	6
Regulatory relationship between macrophage autophagy and PVL-positive methicillin-resistant Staphylococcus aureus	5
Macrophages promote heat stress nephropathy in mice via the C3a-C3aR-TNF pathway	5
Genetic polymorphisms of rs73620203 in the transforming growth interacting factor gene associated with rheumatoid arthritis in a Chinese population	5
Association of neutrophil extracellular trap levels with Raynaud’s phenomenon, glomerulonephritis and disease index score in SLE patients from Brazil	5
Retraction notice to “Increased levels of Th17 cells are associated with non-neuronal acetylcholine in COPD patients” [Immunobiology 219(5) (2014) 392–401]	5
Lactobacillus delbrueckii UFV-H2b20 increases IFN-γ production and CD39+CD73+ Treg cell numbers in lungs, and protects mice against experimental allergic asthma	5
ELAVL1 promotes LPS-induced endothelial cells injury through modulation of cytokine storm	5
Bavachin inhibits IL-4 expression by downregulating STAT6 phosphorylation and GATA-3 expression and ameliorates asthma inflammation in an animal model	5
Immune regulations by 14-3-3: A misty terrain	5
The predictive value of miR-377 and phospholipase A2 in the early diagnosis of diabetic kidney disease and their relationship with inflammatory factors	5
Intestinal production of secreted protein acidic and rich in cysteine (SPARC) in patients with ulcerative colitis	5
Infection by Strongyloides venezuelensis attenuates chronic colitis induced by Dextran Sodium Sulfate ingestion in BALB/c mice	5
Expression profile of MUC1 protein in Pigeon allergens positive asthmatic	5
Toll-like receptor 2 deficiency relieves splenic immunosuppression during sepsis	5
Identification of a novel Immune-Related prognostic model for patients with colorectal cancer based on 3 subtypes	5
An optimized method to visualize the goblet cell-associated antigen passages and identify goblet cells in the intestine, conjunctiva, and airway	5
Antipyretic and anti-inflammatory effects of inosine, an active component of Kangfuxin	5
Seroprevalence and systemic immune biomarkers associated with Toxoplasma gondii infection in blood donors from Southern Brazil	5
Th-1, Th-2, Th-9, Th-17, Th-22 type cytokine concentrations of critical COVID-19 patients after treatment with Remdesivir	4
Why blood group A individuals are at risk whereas blood group O individuals are protected from SARS-CoV-2 (COVID-19) infection: A hypothesis regarding how the virus invades the human body via ABO(H) b	4
A novel peptide vaccination augments cytotoxic CD8+ T-cell responses against Mycobacterium tuberculosis HspX antigen	4
LncRNA SNHG1 overexpression alleviates osteoarthritis via activating PI3K/Akt signal pathway and suppressing autophagy	4
Chlorella vulgaris extract and Imiquimod as new therapeutic targets for leishmaniasis: An immunological approach	4
Development of a novel trivalent invasive non-typhoidal Salmonella outer membrane vesicles based vaccine against salmonellosis and fowl typhoid in chickens	4
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CircEXOC5 promotes ferroptosis by enhancing ACSL4 mRNA stability via binding to PTBP1 in sepsis-induced acute lung injury	4
Apelin triggers macrophage polarization to M2 type in head and neck cancer	4
Nanoparticle-induced immune response: Health risk versus treatment opportunity?	4
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Intrinsic chemical reactivity of activated human complement component C3: A historical glimpse into research during 1979–1980 on the covalent binding properties of C3, C4 and alpha-2 macroglobulin	4
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Involvement of CacyBP/SIP in differentiation and the immune response of HaCaT keratinocytes	4
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Interleukin-1beta triggers the expansion of circulating granulocytic myeloid-derived suppressor cell subset dependent on Erk1/2 activation	4
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Conversion of AML-blasts to leukemia-derived dendritic cells (DCleu) in ‘DC-culture-media’ shifts correlations of released chemokines with antileukemic T-cell reactions	4
Comparable cytokine release ex-vivo by whole blood from COVID-19 patients with and without non-invasive ventilation	4
Deciphering the balance of IL-6/IL-10 cytokines in severe to critical COVID-19 patients	4
Monocyte-derived immature dendritic cells negatively regulate hepatic stellate cells in vitro by secreting IL-10	4
205 The complex role of complement in hepatocellular carcinoma	3
76 C1q-IgM interaction studies with recombinant globular C1q variants	3
221 SYNERGY-1: A Phase 1, first-in-human, randomized, double-blind, placebo-controlled safety, tolerability, immunogenicity, PK and PD study of KP104 in escalating single and multiple doses	3
91 Complement genetics: implementation of a custom made panel for genetic testing of complement-associated kidney patients	3
181 Complement C7 and clusterin form a stable complex in circulation	3
Limosilactobacillus fermentum modulates the gut-airway axis by improving the immune response through FOXP3 activation on combined allergic rhinitis and asthma syndrome (CARAS)	3
134 Mesangial cells derived complement factor H inhibits complement activation and inflammation in IgA Nephropathy	3
Highlighting the versatility of the citrullination process	3
52 Human factor H and properdin modulate SARS-CoV-2 infection in a complement-independent manner	3
245 Sez6L2 is a brain-resident complement inhibitor that is necessary for proper brain development	3
243 Anti-GPC1 IgM activating the complement system is an effective treatment in a pancreatic ductal adenocarcinoma mouse model	3
203 Annexin A2: A positive regulator of the alternative complement pathway in the kidney	3
29 Humoral innate immunity and acute phase proteins in COVID-19	3
6 Development of a C3 humanized rat as a new model for evaluating novel C3 inhibitors	3
55 Association between autoantibodies and complement activation in systemic lupus erythematosus	3
175 Transposon mutagenesis: A molecular switch in Acinetobacter baumannii for rapid adaptation to bacteriophages and the complement system	3
51 Activation of complement in a mouse model of severe COVID-19	3
Interleukin 17, the double-edged sword in atherosclerosis	3
132 Multiple pregnancy can induce preeclampsia-like changes in complement factor H-point mutation mice	3
222 Complement Activation in Cytokine Storms Associated with COVID-19, Sepsis, and Chimeric Antigen Receptor (CAR)-T Therapy	3
94 Citrullination of C1-inhibitor as a mechanism of impaired complement inhibition in rheumatoid arthritis	3
87 Activation of complement pathways and formation of membrane attack complex contribute to the development of severe COVID-19	3
159 Functional characterization of two novel Complement Factor B variants in patients with primary Immune-Complex-mediated MPGN	3
114 Complement protein autoantibodies and increased Factor H related protein four levels may contribute to pathogenesis in IgA nephropathy	3
206 Expression of complement proteins by M1 and M2 macrophages: Complement factor B induces inflammatory macrophage phenotype	3
36 Phase 1 clinical data for single-dose subcutaneous injection of RLYB116, a C5 blocking Affibody® molecule linked to an Albumod® albumin binding domain	3
150 Association between loss of immune checkpoint programmed cell death protein 1 and local synthesis of complement factor B in active ANCA-associated renal vasculitis	3
15 Defining the impact of factor H, factor H-related 1, and factor H-related 5 on C3b deposition on mouse mesangial cells	3
140 A novel selective leukocyte depletion human whole blood model reveals the specific roles of monocytes and granulocytes in the cytokine response to Escherichia coli	3

Arginase is involved in cervical lesions progression and severity	3
44 Bi-specific antibodies targeting C1q and a tumor antigen activate the complement system independent of C1q-Fc interactions	3
72 Elucidation of novel exosite interactions in the activation and control of the classical pathway of complement	3
151 Complement system remains unaltered in an acute schizophrenia	3