American Journal of Chinese Medicine

Papers
(The median citation count of American Journal of Chinese Medicine is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Solasonine Inhibits Cancer Stemness and Metastasis by Modulating Glucose Metabolism via Wnt/β-Catenin/Snail Pathway in Osteosarcoma137
Tanshinone IIA Alleviates Pyroptosis through SIRT1/NLRP3 Pathway to Improve Diabetic Nephropathy68
Chinese Medicine-Derived Salvianolic Acid B for Disease Therapy: A Scientometric Study68
Mast Cells in Acupoint Sensitization: Mechanisms and Research Advances67
Chinese Materia Medica in Treating Depression: The Role of Intestinal Microenvironment58
Ginsenoside Rg6 Improves Cisplatin Resistance in Epithelial Ovarian Cancer Cells via Suppressing Fucosylation and Inducing Autophagy49
Astragalus membranaceus as a Drug Candidate for Inflammatory Bowel Disease: The Preclinical Evidence49
Neuroprotective Effects of Paeonia lactiflora Through the Regulation of Gut Dubosiella in an MPTP-Induced Parkinson’s Disease Mouse Model44
Corrigendum — Gardenia jasminoides Extract GJ-4 Aleviates Memory Defciency of Vascular Dementia in Rats through PERK-Mediated Endoplasmic Reticulum Stress Pathway44
Mechanism of Acupuncture in Treating Obesity: Advances and Prospects43
Research Progress of Chinese Medicine in Treating Chronic Liver Disease by Regulating Autophagy43
Advancing Traditional Chinese Medicine Research through Network Pharmacology: Strategies for Target Identification, Mechanism Elucidation and Innovative Therapeutic Applications42
Multidirectional Intervention of Chinese Herbal Medicine in the Prevention and Treatment of Atherosclerosis: From Endothelial Protection to Immunomodulation38
Silybin for Liver Diseases via Anti-Oxidative Stress: A Comprehensive Review38
Research Progress on the Molecular Mechanisms of Cordycepin in Modulating Inflammation35
Mechanism of Quercetin and Luteolin on Colon Cancer Metastasis: Network Pharmacological Study and Experimental Validation34
Personalized Traditional Chinese Medicine in Oncology: Bridging the Macro State with Micro Targets32
Gambogic Acid, a Caged Xanthone: Therapeutic Effects, Pharmacokinetics, Toxicological Properties, and Delivery Platforms30
20(S)-Protopanaxadiol fromPanax ginsengInduces Apoptosis and Autophagy in Gastric Cancer Cells by Inhibiting Src29
The Role of Traditional Chinese Medicine in Targeting NF-κB Ubiquitination Against Ischemic Stroke28
Ginsenoside Rb1 Relieves Cellular Senescence and Pulmonary Fibrosis by Promoting NRF2/QKI/SMAD7 Axis28
Formononetin Alleviates Ischemic Acute Kidney Injury by Regulating Macrophage Polarization through KLF6/STAT3 Pathway27
The Role of Artesunate in Cancer Management: Mechanisms of Biomedical Effects and Toxicology27
Mangiferin Protects against Angiotensin-II-Enhanced Hypertrophic Markers and Apoptosis in H9c2 Cardiomyocytes26
Probiotic Fermentation of Herbal Medicine: Progress, Challenges, and Opportunities26
Research Progress on Traditional Uses, Chemical Composition, Pharmacological Actions, and Clinical Applications of Ginseng-Containing Sijunzi Decoction25
Catalpol from Rehmannia glutinosa Targets Nrf2/NF-κB Signaling Pathway to Improve Renal Anemia and Fibrosis24
Ethnomedicine, Botany, Phytochemistry, Pharmacology, Pharmacokinetics, and Toxicity of Rhizoma Corydalis: A Systematic Review24
Traditional Chinese Patent Medicine in the Treatment of Alzheimer’s Disease: A Systematic Review and Network Meta-Analysis24
Liquiritigenin, an Active Ingredient of Liquorice, Alleviates Acute Kidney Injury by VKORC1-Mediated Ferroptosis Inhibition23
Nobiletin Ameliorated the Development of Diabetic Kidney Disease via Modulating Ferroptosis and Epithelial–Mesenchymal Transition Involving Gut–Kidney Axis23
Efficacy of Oriental Exercises for Non-Motor Symptoms and Quality of Life in Parkinson’s Disease: A Systematic Review and Meta-Analysis22
The Role of Traditional Chinese Medicine in Cancer Immunotherapy: Current Status and Future Directions22
Ginsenoside Rd Attenuates Myocardial Ischemia/Reperfusion Injury by Inhibiting Inflammation and Apoptosis through PI3K/Akt Signaling Pathway21
Cinnamon for Metabolic Diseases and Their Cardiovascular and Hepatic Complications: A Mechanistic Review21
Cinnamaldehyde Ameliorates Ischemic Heart Failure by Targeting USP18 to Inhibit β1-Adrenergic Receptor Ubiquitination and Suppress TAK1/NF-κB Signaling Pathway21
Chinese Medicine for the Treatment of Liver Cirrhosis: The Mechanism of Cellular Autophagy21
Traditional Chinese Medicine in Osteoporosis Intervention and the Related Regulatory Mechanism of Gut Microbiome21
Polygonati Rhizoma: Geographic Distribution, Traditional Use, Component Transformation, Pharmacological Activity, and Clinical Application20
Targeting Myeloperoxidase in Disease Pathogenesis: Emerging Roles of Natural Products in Therapeutic Modulation20
Research Progress on the Antitumor Molecular Mechanism of Ginsenoside Rh220
Xanthohumol Promotes Skp2 Ubiquitination Leading to the Inhibition of Glycolysis and Tumorigenesis in Ovarian Cancer20
Research Progress of Immunomodulation on Anti-COVID-19 and the Effective Components from Traditional Chinese Medicine19
Astragaloside IV Improves Pulmonary Vascular Endothelial Dysfunction in Pulmonary Arterial Hypertension by Inhibiting Ferroptosis through Modulation of the Calpain-1/TGF-β/TFRC Pathway19
NOTICE OF RETRACTION: Therapeutic Prospects of Ursolic Acid in Colorectal Cancer: Modulation of the Wnt/β-Catenin Signaling Pathway and Gut Microbiota Composition18
Quercetin Ameliorates Learning and Memory in OVX/D-gal-Induced Alzheimer’s Disease in Rats by Inhibiting Neuroinflammation via cGAS-STING Signal Pathway18
New Perspectives on Chinese Medicine in Treating Hepatic Fibrosis: Lipid Droplets in Hepatic Stellate Cells18
Mechanisms of Dihydromyricetin for Improving Hepatic Fibrosis through the Integration of Metabolomics and Gut Microbiota18
Celastrol Alleviates Intestinal Epithelial Permeability by Inhibiting Ferroptosis through PI3K/Akt/FOXO1/HO-1 Signaling Pathway18
Targeting Ferroptosis in Cancer by Natural Products: An Updated Review18
Poria cocos Polysaccharides Attenuate Cardiac Injury by Inhibiting CaMKII-Mediated P38/NF-κB/NLRP3 Signaling Pathway to Reduce Sepsis-Induced Apoptosis and Inflammation18
Research Progress of Traditional Chinese Medicine Monomers in Reversing Multidrug Resistance of Breast Cancer18
Cistanche deserticola Polysaccharides Mitigate Alzheimer’s Disease Progression by Dynamic Regulation of Gut Microbiota Composition and Metabolites17
IL-10-dependent Effect of Chinese Medicine Abelmoschus manihot on Alleviating Intestinal Inflammation and Modulating Gut Microbiota17
Prenylated Flavonoids in Sophora flavescens: A Systematic Review of Their Phytochemistry and Pharmacology17
Coptis chinensis-Induced Changes in Metabolomics and Gut Microbiota in Rats17
Andrographolide Inhibits Lipotoxicity-Induced Activation of the NLRP3 Inflammasome in Bone Marrow-Derived Macrophages17
Regulation of Traditional Chinese Medicine Gut Microbiota Short-Chain Fatty Acid Axis in Type 2 Diabetes Management: A Review16
Efficacy and Mechanisms of Natural Products as Therapeutic Interventions for Chronic Respiratory Diseases16
Ruscogenin Alleviates Myocardial Ischemia via Myosin IIA-Dependent Mitochondrial Fusion and Fission Balance16
Curcumin Analog L48H37 Induces Apoptosis in Human Oral Cancer Cells by Activating Caspase Cascades and Downregulating the Inhibitor of Apoptosis Proteins through JNK/p38 Signaling16
Ginsenoside Rg5 Improves Sleep by Regulating Energy Metabolism in Sleep-Deprived Rats16
Pharmacological Effects of a Ginseng-Containing Chinese Medicine Formula in Treating Hepatocellular Carcinoma Based on Comprehensive Bioinformatics and Experimental Validation16
ERRATUM — The Effects of Patchouli Alcohol on Diarrhea-Predominant Irritable Bowel Syndrome are Correlated with Phenotypic Plasticity in Myenteric Neurons and the Targeted Regulation of Myosin Va16
Advances in the Application of Traditional Chinese Medicine Using Artificial Intelligence: A Review15
Triterpenoid Compounds from Cyclocarya paliurus: A Review of Their Phytochemistry, Quality Control, Pharmacology, and Structure–Activity Relationship15
Astragaloside IV Alleviates Doxorubicin-Induced Cardiotoxicity by Inhibiting Cardiomyocyte Pyroptosis through the SIRT1/NLRP3 Pathway15
Therapeutic Potential of Traditional Chinese Medicine Against Osteoarthritis: Targeting the Wnt Signaling Pathway15
CORRIGENDUM: Protective Effects of Ginsenosides on 17α-Ethynyelstradiol-Induced Intrahepatic Cholestasis via Anti-Oxidative and Anti-Inflammatory Mechanisms in Rats14
Anticancer Effects of Morusin in Prostate Cancer via Inhibition of Akt/mTOR Signaling Pathway14
Research Progress of Chinese Medicine in the Regulation of Liver Fibrosis-Related Signaling Pathways14
The Role ofGynostemma pentaphyllumin Regulating Hyperlipidemia14
Traditional Chinese Medicine Formulae and Chinese Patent Medicines for the Treatment of Diabetic Kidney Disease: Efficacies and Mechanisms14
Therapeutic Effects ofAlisma orientaleand its Active Constituents on Cardiovascular Disease and Obesity14
Research Progress in Traditional Chinese Medicine for the Treatment of Breast Cancer13
Mechanistic Role ofScutellaria baicalensisGeorgi in Breast Cancer Therapy13
Chicoric Acid Presented NLRP3-Mediated Pyroptosis through Mitochondrial Damage by PDPK1 Ubiquitination in an Acute Lung Injury Model13
Ginsenoside Rk1 Ameliorates ER Stress-Induced Apoptosis through Directly Activating IGF-1R in Mouse Pancreatic β-Cells and Diabetic Pancreas13
Molecular Mechanisms of Traditional Chinese Medicine in Treating Osteoarthritis13
Chinese Medicine in Regulating Immune Balance for the Treatment of Autoimmune Diseases13
Baicalin Blocks Colon Cancer Cell Cycle and Inhibits Cell Proliferation through miR-139-3p Upregulation by Targeting CDK1613
Acupuncture: A Review of the Safety and Adverse Events and the Strategy of Potential Risk Prevention13
Research Progress on Traditional Chinese Medicine in Regulating Inflammatory Pathways of the Gut–Kidney Axis in Diabetic Kidney Disease13
Advances and Perspectives on the Anti-Fibrotic Mechanisms of the Quercetin13
Unraveling the Mechanisms of Active Saponins from Rhizoma Anemarrhenae Against Ferroptosis in Alzheimer’s Disease: Integrating Network Pharmacology, Cell Membrane Chromatography, and Experiment12
Sanguinarine Inhibits Gastric Cancer Progression by Targeting the NOS2/SOD1 Axis to Promote Ferroptosis12
Application of Large Language Models in Traditional Chinese Medicine: A State-of-the-Art Review12
Botany, Traditional Use, Phytochemistry, Pharmacology and Clinical Applications of Rhubarb (Rhei Radix et Rhizome): A Systematic Review12
Effects of Chinese Medicine on Pyroptosis in Coronary Heart Disease12
Veratramine Inhibits the Cell Cycle Progression, Migration, and Invasion via ATM/ATR Pathway in Androgen-Independent Prostate Cancer12
Therapeutic Potentials of Medicinal Leech in Chinese Medicine12
Taraxacum: A Review of Ethnopharmacology, Phytochemistry and Pharmacological Activity12
Isoliquiritigenin Inhibits Oral Squamous Cell Carcinoma and Overcomes Chemoresistance by Destruction of Survivin12
Bergenin Inhibits Tumor Growth and Overcomes Radioresistance by Targeting Aerobic Glycolysis12
Astragaloside I from Astragalus Attenuates Diabetic Kidney Disease by Regulating HDAC3/Klotho/TGF-β1 Loop12
Gardenia jasminoidesExtract GJ-4 Alleviates Memory Deficiency of Vascular Dementia in Rats through PERK-Mediated Endoplasmic Reticulum Stress Pathway11
Panax notoginseng Saponins Activate Nuclear Factor Erythroid 2-Related Factor 2 to Inhibit Ferroptosis and Attenuate Inflammatory Injury in Cerebral Ischemia–Reperfusion11
Chlorogenic Acid Ameliorates Acetaminophen-Induced Liver Injury Through AMPK/mTOR/ULK1-Mediated Autophagy Activation11
Targeting Autophagy with Geniposide Ameliorates Atherosclerosis in ApoE−∕− Mice11
Traditional Chinese Medicine: A Promising Treatment Option for Intestinal Fibrosis11
Glycyrrhizin and the Related Preparations: An Inspiring Resource for the Treatment of Liver Diseases11
The Phytochemistry of Ganoderma Species and their Medicinal Potentials11
Electroacupuncture Reprograms Gut Microbiota and Confers Cerebral Protection After Stroke through Enhanced Regulatory T Cell Response11
Astragaloside IV Ameliorates Colonic Adenomatous Polyps Development by Orchestrating Gut Bifidobacterium and Serum Metabolome11
Flavonoids from Radix Puerariae Alleviated Alcoholic Liver Disease via PI3K/AKT Signaling Pathway11
Pharmacokinetics and Biological Activities of Notoginsenoside R1: A Systematical Review11
Traditional Chinese Herbal Medicine for Allergic Diseases: A Review11
Application of Traditional Chinese Medicine in Alzheimer’s Disease Treatment: A Focus on the Wnt/β-Catenin Pathway11
Effects of Curcuminoids and Surfactant-Formulated Curcumin on Chemo-Resistant Colorectal Cancer10
Bufalin Inhibits Tumorigenesis and SREBP-1-Mediated Lipogenesis in Hepatocellular Carcinoma via Modulating the ATP1A1/CA2 Axis10
Trends and Characteristics of the Whole-Grain Diet10
Red Yeast Rice and Statin Therapy in Patients with Hypercholesterolemia and the Comorbidities: A Retrospective Cohort Study on Lipid-Lowering Effects and Cardiovascular Outcomes10
Acupuncture for Rheumatoid Arthritis Treatment: Biological Mechanisms of Anti-Inflammation and Analgesia10
Schisanhenol Attenuates OxLDL-Induced Endothelial Dysfunction via an AMPK-Dependent Mechanism10
Calycosin Enhances Heat Shock Related-Proteins in H9c2 Cells to Modulate Survival and Apoptosis against Heat Shock10
Curcumol Reduces Aerobic Glycolysis and Overcomes Chemoresistance by Inducing Cdh1-Mediated Skp2 Ubiquitination10
Osthole, a Coumarin from Cnidium monnieri: A Review on Its Pharmacology, Pharmacokinetics, Safety, and Innovative Drug Delivery Platforms10
Therapeutic Targets and Natural Product Screening for Cognitive Impairments Associated with Ferroptosis in Wilson’s Disease10
Triptolide from Tripterygium wilfordii Suppresses Glycolysis and Induces Cuproptosis via the HK2/DLAT Signaling Pathway in Colorectal Cancer10
Chinese Medicine for Non-Alcoholic Fatty Liver Disease: Targeting Key Signaling Pathways10
Traditional Chinese Medicine for Cancer Treatment10
The Effectiveness of Traditional Chinese Medicine in Treating Malignancies via Regulatory Cell Death Pathways and the Tumor Immune Microenvironment: A Review of Recent Advances9
Narciclasine Induces Caspase Cascade Activation and Cell Apoptosis via JNK Signaling in Oral Cancer9
Valeriana Jatamansi: An Overview of Phytochemistry, Pharmacology, Clinical Prospects, and Network Analysis of Drug Targets9
Role of Traditional Chinese Medicine in Lung Cancer Management: A Review9
Research Progress in Ulcerative Colitis: The Role of Traditional Chinese Medicine on Gut Microbiota and Signaling Pathways9
Ferroptosis in Endometriosis: Traditional Chinese Medicine Interventions and Mechanistic Insights9
The Effectiveness of Acupuncture for Low Back Pain: An Umbrella Review and Meta-Analysis9
A Review of Traditional Chinese Medicine for Triple Negative Breast Cancer and the Pharmacological Mechanisms9
The Pharmacology and Toxicology of Ginkgolic Acids: Secondary Metabolites from Ginkgo biloba9
Rutaecarpine Alleviates Early Brain Injury-Induced Inflammatory Response Following Subarachnoid Hemorrhage via SIRT6/NF-κB Pathway9
Astragalus membranaceus Polysaccharide Regulates Small Intestinal Microbes and Activates IL-22 Signal Pathway to Promote Intestinal Stem Cell Regeneration in Aging Mice9
Ginkgo biloba : The Traditional Use, Phytochemistry, Pharmacology, and Therapeutic Applications9
ERRATUM: Paris polyphylla Suppresses Proliferation and Vasculogenic Mimicry of Human Osteosarcoma Cells and Inhibits Tumor Growth 9
Paeoniflorin Alleviates Metabolic Dysfunction-Associated Fatty Liver Disease by Targeting STING-Mediated Pyroptosis via Inhibiting the NLRP3 Inflammasome9
Amelioration of Lung Fibrosis by Total Flavonoids of Astragalus via Inflammatory Modulation and Epithelium Regeneration9
Total Saponins of Panax notoginseng Leaves Alleviate Vascular Dementia via the Gut–Brain Axis8
Cordycepin: A Promising Anticancer Compound from Traditional Chinese Medicine8
The Role of Traditional Chinese Medicine in the Management of Nonalcoholic Fatty Liver Disease: Targeting Gut Microbiome8
Pharmacological Effects of Licorice ( Glycyrrhiza spp.) and Its Bioactive Constituents: The Perspective of Intestinal Microbiota8
Ginkgo biloba and Its Chemical Components in the Management of Alzheimer’s Disease8
Effects of Resveratrol on Pulmonary Fibrosis via TGF-β/Smad/ERK Signaling Pathway8
A Novel Paradigm Defines Functional Molecule Clusters for an Anti-Alzheimer’s Disease Recipe from Traditional Chinese Medicine8
Berberine Metabolites Stimulate GLP-1 Secretion by Alleviating Oxidative Stress and Mitochondrial Dysfunction8
The Role of Traditional Chinese Medicine in the Management of Cervical Cancer8
Renoprotective Effect of Isoorientin in Diabetic Nephropathy via Activating Autophagy and Inhibiting the PI3K-AKT-TSC2-mTOR Pathway8
Notoginsenoside R1 Ameliorates Myocardial Ischemia/Reperfusion Injury by Suppressing Apoptosis via Activating Wnt/β-Catenin Signaling8
Phytochemical Insights into Panax Genus Metabolites: Evidence-Based Fatigue Intervention via Ethnopharmacological and Biomedical Perspectives8
Ginsenoside Re Attenuates Cisplatin-Induced Intestinal Toxicity via Suppressing GSK-3β-Dependent Wnt/β-Catenin Signaling Pathway In Vivo and In Vitro8
Gut Microbiota Regulation by Acupuncture and Moxibustion: A Systematic Review and Meta-Analysis8
Eugenol Exerted Significant Anti-Oxidant and Anti-Inflammatory Effects on Experimental Colitis via Directly Acting on PPAR-γ8
Pharmacological Benefits and Underlying Mechanisms of Salvia miltiorrhiza against Molecular Pathology of Various Liver Diseases: A Review8
Curcumin for the Treatment of Inflammatory Bowel Disease: From Mechanism to Clinic7
The Role of Traditional Chinese Medicines in the Treatment of Osteoporosis7
Anti-Inflammatory and Anti-oxidative Effects of Puerarin in Postmenopausal Cardioprotection: Roles of Akt and Heme Oxygenase-17
Total Flavonoids of Astragalus Inhibit Activated CD4+ T Cells and Regulate Differentiation of Th17/Th1/Treg Cells in Experimental Autoimmune Encephalomyelitis Mice by JAK/STAT and NFκB Signaling Pathw7
Application of Panax ginseng in the Treatment of Chronic Airway Diseases7
The Pharmacological Effects of Gastrodin and the Progress in the Treatment of Neurological Disorders7
Apigenin Suppresses Innate Immune Responses and Ameliorates Lipopolysaccharide-Induced Inflammation via Inhibition of STING/IRF3 Pathway7
A Comprehensive Review of Licorice: The Preparation, Chemical Composition, Bioactivities and Its Applications7
Acupuncture for Neuropathic Pain: Mechanisms, Clinical Efficacy and Future Perspectives7
Efficacy and Safety of Glycyrrhizic Acid in Treatment of Autoimmune Hepatitis7
Traditional Chinese Medicine for Alzheimer’s Disease: A Systematic Review and Meta-Analysis7
Maslinic Acid Ameliorates Myocardial Ischemia Reperfusion Injury-Induced Oxidative Stress via Activating Nrf2 and Inhibiting NF-κB Pathways6
Acupuncture for Fibromyalgia: A Review Based on Multidimensional Evidence6
Triptolide Attenuates Renal Slit Diagram to Tight Junction Transition in Diabetic Kidney Disease by Regulating Nrf2–Ferroptosis Pathway6
Biometrics Data Visualization of Ginsenosides in Anticancer Investigations6
Cancer Pain Management with Traditional Chinese Medicine: Current Status and Future Perspectives6
Therapeutic Effects of Natural Products in the Treatment of Chronic Diseases: The Role in Regulating KEAP1–NRF2 Pathway6
Korean Red Ginseng Marc-Derived Gintonin Improves Alzheimer’s Cognitive Dysfunction by Upregulating LPAR16
Phycocyanin: Biomedical Activities and Related Mechanisms of Action6
Berberine Alleviates Ischemic Brain Injury by Enhancing Autophagic Flux via Facilitation of TFEB Nuclear Translocation6
Effectiveness of Chinese Herbal Medicine in Patients with COVID-19 During the Omicron Wave in Hong Kong: A Retrospective Case-Controlled Study6
Chinese Herbal Medicine, Alternative or Complementary, for Endometriosis-Associated Pain: A Meta-Analysis6
Ginseng as a Key Immune Response Modulator in Chinese Medicine: From Antipandemic History to COVID-19 Management6
Cannabidiol Reprograms Glucose Metabolism in Colorectal Adenocarcinoma by Targeting HIF-1α/LDHA Pathway6
Acupuncture and Moxibustion for Inflammatory Bowel Disease: Regulatory Mechanisms Revealed by Microbiome and Metabolomic Analysis6
Effects and Mechanistic Role of Mulberry Leaves in Treating Diabetes and its Complications6
Study on the Chemical Constituents, Pharmacological Activities, and Clinical Application of Taxus6
Puerarin Attenuates Myocardial Ischemia-Reperfusion Damage by Targeting Ferroptosis through 14-3-3η Modulation6
Review on Processing Methods of Toxic Chinese Materia Medica and the Related Mechanisms of Action6
Geniposide Suppresses Tumor Progression Through DUOX1-Mediated Ferroptosis in Hepatocellular Carcinoma6
The Role of Chinese Medicine in the Treatment of Chronic Hepatitis B6
Integrated Metabonomic Study on the Relationship between Medicinal Properties and Efficacy ofRehmanniae Radix6
Sophora alopecuroides Alleviates Neuroinflammation and Oxidative Damage of Parkinson’s Disease In Vitro and In Vivo6
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