American Journal of Chinese Medicine

Article	Citations
Astragalus membranaceus as a Drug Candidate for Inflammatory Bowel Disease: The Preclinical Evidence	144
Mast Cells in Acupoint Sensitization: Mechanisms and Research Advances	75
Neuroprotective Effects of Paeonia lactiflora Through the Regulation of Gut Dubosiella in an MPTP-Induced Parkinson’s Disease Mouse Model	73
Ginsenoside Rg6 Improves Cisplatin Resistance in Epithelial Ovarian Cancer Cells via Suppressing Fucosylation and Inducing Autophagy	70
Chinese Medicine-Derived Salvianolic Acid B for Disease Therapy: A Scientometric Study	59
Tanshinone IIA Alleviates Pyroptosis through SIRT1/NLRP3 Pathway to Improve Diabetic Nephropathy	52
Modulation of Ferroptosis: A Novel Mechanism of Traditional Chinese Medicine in Managing Chronic Atrophic Gastritis	52
Chinese Materia Medica in Treating Depression: The Role of Intestinal Microenvironment	51
Solasonine Inhibits Cancer Stemness and Metastasis by Modulating Glucose Metabolism via Wnt/β-Catenin/Snail Pathway in Osteosarcoma	49
Corrigendum — Gardenia jasminoides Extract GJ-4 Aleviates Memory Defciency of Vascular Dementia in Rats through PERK-Mediated Endoplasmic Reticulum Stress Pathway	48
Research Progress of Chinese Medicine in Treating Chronic Liver Disease by Regulating Autophagy	46
Mitochondria-Associated Ferroptosis and Diabetic Osteoporosis: Exploration of Traditional Chinese Medicine Treatment and Mechanisms of Action	45
Mechanism of Acupuncture in Treating Obesity: Advances and Prospects	40
Advancing Traditional Chinese Medicine Research through Network Pharmacology: Strategies for Target Identification, Mechanism Elucidation and Innovative Therapeutic Applications	39
Silybin for Liver Diseases via Anti-Oxidative Stress: A Comprehensive Review	38
Research Progress on the Molecular Mechanisms of Cordycepin in Modulating Inflammation	34
Gambogic Acid, a Caged Xanthone: Therapeutic Effects, Pharmacokinetics, Toxicological Properties, and Delivery Platforms	34
Mechanism of Quercetin and Luteolin on Colon Cancer Metastasis: Network Pharmacological Study and Experimental Validation	34
20(S)-Protopanaxadiol fromPanax ginsengInduces Apoptosis and Autophagy in Gastric Cancer Cells by Inhibiting Src	33
Ginsenoside Rb1 Relieves Cellular Senescence and Pulmonary Fibrosis by Promoting NRF2/QKI/SMAD7 Axis	33
Personalized Traditional Chinese Medicine in Oncology: Bridging the Macro State with Micro Targets	32
The Role of Traditional Chinese Medicine in Targeting NF-κB Ubiquitination Against Ischemic Stroke	31
Probiotic Fermentation of Herbal Medicine: Progress, Challenges, and Opportunities	30
Multidirectional Intervention of Chinese Herbal Medicine in the Prevention and Treatment of Atherosclerosis: From Endothelial Protection to Immunomodulation	27
Traditional Chinese Patent Medicine in the Treatment of Alzheimer’s Disease: A Systematic Review and Network Meta-Analysis	27

Formononetin Alleviates Ischemic Acute Kidney Injury by Regulating Macrophage Polarization through KLF6/STAT3 Pathway	27
Research Progress on Traditional Uses, Chemical Composition, Pharmacological Actions, and Clinical Applications of Ginseng-Containing Sijunzi Decoction	27
The Role of Artesunate in Cancer Management: Mechanisms of Biomedical Effects and Toxicology	27
Traditional Chinese Medicine in Osteoporosis Intervention and the Related Regulatory Mechanism of Gut Microbiome	26
Ginsenoside Rd Attenuates Myocardial Ischemia/Reperfusion Injury by Inhibiting Inflammation and Apoptosis through PI3K/Akt Signaling Pathway	26
Efficacy of Oriental Exercises for Non-Motor Symptoms and Quality of Life in Parkinson’s Disease: A Systematic Review and Meta-Analysis	25
Cinnamon for Metabolic Diseases and Their Cardiovascular and Hepatic Complications: A Mechanistic Review	25
Catalpol from Rehmannia glutinosa Targets Nrf2/NF-κB Signaling Pathway to Improve Renal Anemia and Fibrosis	24
The Role of Traditional Chinese Medicine in Cancer Immunotherapy: Current Status and Future Directions	24
Chinese Medicine for the Treatment of Liver Cirrhosis: The Mechanism of Cellular Autophagy	24
Mangiferin Protects against Angiotensin-II-Enhanced Hypertrophic Markers and Apoptosis in H9c2 Cardiomyocytes	23
Nobiletin Ameliorated the Development of Diabetic Kidney Disease via Modulating Ferroptosis and Epithelial–Mesenchymal Transition Involving Gut–Kidney Axis	22
Liquiritigenin, an Active Ingredient of Liquorice, Alleviates Acute Kidney Injury by VKORC1-Mediated Ferroptosis Inhibition	22
Xanthohumol Promotes Skp2 Ubiquitination Leading to the Inhibition of Glycolysis and Tumorigenesis in Ovarian Cancer	22
Cinnamaldehyde Ameliorates Ischemic Heart Failure by Targeting USP18 to Inhibit β1-Adrenergic Receptor Ubiquitination and Suppress TAK1/NF-κB Signaling Pathway	22
Ethnomedicine, Botany, Phytochemistry, Pharmacology, Pharmacokinetics, and Toxicity of Rhizoma Corydalis: A Systematic Review	22
Research Progress of Immunomodulation on Anti-COVID-19 and the Effective Components from Traditional Chinese Medicine	21
Astragaloside IV Improves Pulmonary Vascular Endothelial Dysfunction in Pulmonary Arterial Hypertension by Inhibiting Ferroptosis through Modulation of the Calpain-1/TGF-β/TFRC Pathway	21
Targeting Myeloperoxidase in Disease Pathogenesis: Emerging Roles of Natural Products in Therapeutic Modulation	20
Poria cocos Polysaccharides Attenuate Cardiac Injury by Inhibiting CaMKII-Mediated P38/NF-κB/NLRP3 Signaling Pathway to Reduce Sepsis-Induced Apoptosis and Inflammation	20
Mechanisms of Dihydromyricetin for Improving Hepatic Fibrosis through the Integration of Metabolomics and Gut Microbiota	20
Research Progress on the Antitumor Molecular Mechanism of Ginsenoside Rh2	20
Polygonati Rhizoma: Geographic Distribution, Traditional Use, Component Transformation, Pharmacological Activity, and Clinical Application	20
Celastrol Alleviates Intestinal Epithelial Permeability by Inhibiting Ferroptosis through PI3K/Akt/FOXO1/HO-1 Signaling Pathway	20
New Perspectives on Chinese Medicine in Treating Hepatic Fibrosis: Lipid Droplets in Hepatic Stellate Cells	19
Quercetin Ameliorates Learning and Memory in OVX/D-gal-Induced Alzheimer’s Disease in Rats by Inhibiting Neuroinflammation via cGAS-STING Signal Pathway	19
Research Progress of Traditional Chinese Medicine Monomers in Reversing Multidrug Resistance of Breast Cancer	19
Andrographolide Inhibits Lipotoxicity-Induced Activation of the NLRP3 Inflammasome in Bone Marrow-Derived Macrophages	19
Targeting Ferroptosis in Cancer by Natural Products: An Updated Review	18
Cistanche deserticola Polysaccharides Mitigate Alzheimer’s Disease Progression by Dynamic Regulation of Gut Microbiota Composition and Metabolites	18
IL-10-dependent Effect of Chinese Medicine Abelmoschus manihot on Alleviating Intestinal Inflammation and Modulating Gut Microbiota	18
NOTICE OF RETRACTION: Therapeutic Prospects of Ursolic Acid in Colorectal Cancer: Modulation of the Wnt/β-Catenin Signaling Pathway and Gut Microbiota Composition	18
Prenylated Flavonoids in Sophora flavescens: A Systematic Review of Their Phytochemistry and Pharmacology	18
Coptis chinensis-Induced Changes in Metabolomics and Gut Microbiota in Rats	18
Pharmacological Effects of a Ginseng-Containing Chinese Medicine Formula in Treating Hepatocellular Carcinoma Based on Comprehensive Bioinformatics and Experimental Validation	17
ERRATUM — The Effects of Patchouli Alcohol on Diarrhea-Predominant Irritable Bowel Syndrome are Correlated with Phenotypic Plasticity in Myenteric Neurons and the Targeted Regulation of Myosin Va	17
Efficacy and Mechanisms of Natural Products as Therapeutic Interventions for Chronic Respiratory Diseases	17
Therapeutic Potential of Traditional Chinese Medicine Against Osteoarthritis: Targeting the Wnt Signaling Pathway	17
Ruscogenin Alleviates Myocardial Ischemia via Myosin IIA-Dependent Mitochondrial Fusion and Fission Balance	17
Advances in the Application of Traditional Chinese Medicine Using Artificial Intelligence: A Review	16
Research Progress of Chinese Medicine in the Regulation of Liver Fibrosis-Related Signaling Pathways	16
Ginsenoside Rg5 Improves Sleep by Regulating Energy Metabolism in Sleep-Deprived Rats	16
Astragaloside IV Ameliorates Diabetic Kidney Disease via Inhibiting MAPK Pathway and Alleviating Metabolic Dysregulation	16
CORRIGENDUM: Protective Effects of Ginsenosides on 17α-Ethynyelstradiol-Induced Intrahepatic Cholestasis via Anti-Oxidative and Anti-Inflammatory Mechanisms in Rats	16
Curcumin Analog L48H37 Induces Apoptosis in Human Oral Cancer Cells by Activating Caspase Cascades and Downregulating the Inhibitor of Apoptosis Proteins through JNK/p38 Signaling	16
Astragaloside IV Alleviates Doxorubicin-Induced Cardiotoxicity by Inhibiting Cardiomyocyte Pyroptosis through the SIRT1/NLRP3 Pathway	16
Regulation of Traditional Chinese Medicine Gut Microbiota Short-Chain Fatty Acid Axis in Type 2 Diabetes Management: A Review	16
Progress of Traditional Chinese Medicine in Targeting Ferroptosis to Combat Cerebral Ischemia–Reperfusion Injury	15
Anticancer Effects of Morusin in Prostate Cancer via Inhibition of Akt/mTOR Signaling Pathway	15
Therapeutic Effects ofAlisma orientaleand its Active Constituents on Cardiovascular Disease and Obesity	15

Traditional Chinese Medicine Formulae and Chinese Patent Medicines for the Treatment of Diabetic Kidney Disease: Efficacies and Mechanisms	15
Mechanistic Role ofScutellaria baicalensisGeorgi in Breast Cancer Therapy	15
The Role ofGynostemma pentaphyllumin Regulating Hyperlipidemia	15
Molecular Mechanisms of Traditional Chinese Medicine in Treating Osteoarthritis	15
Acupuncture: A Review of the Safety and Adverse Events and the Strategy of Potential Risk Prevention	15
Ginsenoside Rk1 Ameliorates ER Stress-Induced Apoptosis through Directly Activating IGF-1R in Mouse Pancreatic β-Cells and Diabetic Pancreas	15
Research Progress in Traditional Chinese Medicine for the Treatment of Breast Cancer	15
Triterpenoid Compounds from Cyclocarya paliurus: A Review of Their Phytochemistry, Quality Control, Pharmacology, and Structure–Activity Relationship	15
Chinese Medicine in Regulating Immune Balance for the Treatment of Autoimmune Diseases	15
Bergenin Inhibits Tumor Growth and Overcomes Radioresistance by Targeting Aerobic Glycolysis	14
Ginsenoside Rg3 in Cancer Therapy: Pharmacokinetics, Molecular Mechanisms, and Synergistic Combinations	14
Advances and Perspectives on the Anti-Fibrotic Mechanisms of the Quercetin	14
Baicalin Blocks Colon Cancer Cell Cycle and Inhibits Cell Proliferation through miR-139-3p Upregulation by Targeting CDK16	14
Sanguinarine Inhibits Gastric Cancer Progression by Targeting the NOS2/SOD1 Axis to Promote Ferroptosis	14
Research Progress on Traditional Chinese Medicine in Regulating Inflammatory Pathways of the Gut–Kidney Axis in Diabetic Kidney Disease	14
Chicoric Acid Presented NLRP3-Mediated Pyroptosis through Mitochondrial Damage by PDPK1 Ubiquitination in an Acute Lung Injury Model	14
Application of Large Language Models in Traditional Chinese Medicine: A State-of-the-Art Review	14
Isoliquiritigenin Inhibits Oral Squamous Cell Carcinoma and Overcomes Chemoresistance by Destruction of Survivin	14
Veratramine Inhibits the Cell Cycle Progression, Migration, and Invasion via ATM/ATR Pathway in Androgen-Independent Prostate Cancer	13
Effects of Chinese Medicine on Pyroptosis in Coronary Heart Disease	13
Notoginsenoside R1 Alleviates Acetaminophen-Induced Liver Injury via MAPK/mTOR-Mediated Autophagy	13
Traditional Chinese Medicine: A Promising Treatment Option for Intestinal Fibrosis	13
Glycyrrhizin and the Related Preparations: An Inspiring Resource for the Treatment of Liver Diseases	13
Astragaloside I from Astragalus Attenuates Diabetic Kidney Disease by Regulating HDAC3/Klotho/TGF-β1 Loop	13
Taraxacum: A Review of Ethnopharmacology, Phytochemistry and Pharmacological Activity	13
Botany, Traditional Use, Phytochemistry, Pharmacology and Clinical Applications of Rhubarb (Rhei Radix et Rhizome): A Systematic Review	13
Flavonoids from Radix Puerariae Alleviated Alcoholic Liver Disease via PI3K/AKT Signaling Pathway	13
Unraveling the Mechanisms of Active Saponins from Rhizoma Anemarrhenae Against Ferroptosis in Alzheimer’s Disease: Integrating Network Pharmacology, Cell Membrane Chromatography, and Experiment	13
Therapeutic Potentials of Medicinal Leech in Chinese Medicine	13
Luteolin Triggers Pyroptosis in Pancreatic Ductal Adenocarcinoma by Inhibiting Mitochondrial Fission through the RAS/ERK/DRP1 Pathway	13
Gardenia jasminoidesExtract GJ-4 Alleviates Memory Deficiency of Vascular Dementia in Rats through PERK-Mediated Endoplasmic Reticulum Stress Pathway	13
Panax notoginseng Saponins Activate Nuclear Factor Erythroid 2-Related Factor 2 to Inhibit Ferroptosis and Attenuate Inflammatory Injury in Cerebral Ischemia–Reperfusion	13
Application of Traditional Chinese Medicine in Alzheimer’s Disease Treatment: A Focus on the Wnt/β-Catenin Pathway	12
The Phytochemistry of Ganoderma Species and their Medicinal Potentials	12
Effects of Curcuminoids and Surfactant-Formulated Curcumin on Chemo-Resistant Colorectal Cancer	12
Therapeutic Targets and Natural Product Screening for Cognitive Impairments Associated with Ferroptosis in Wilson’s Disease	12
Pharmacokinetics and Biological Activities of Notoginsenoside R1: A Systematical Review	12
Astragaloside IV Ameliorates Colonic Adenomatous Polyps Development by Orchestrating Gut Bifidobacterium and Serum Metabolome	12
Electroacupuncture Reprograms Gut Microbiota and Confers Cerebral Protection After Stroke through Enhanced Regulatory T Cell Response	12
Trends and Characteristics of the Whole-Grain Diet	12
Chlorogenic Acid Ameliorates Acetaminophen-Induced Liver Injury Through AMPK/mTOR/ULK1-Mediated Autophagy Activation	12
Traditional Chinese Herbal Medicine for Allergic Diseases: A Review	12
Schisanhenol Attenuates OxLDL-Induced Endothelial Dysfunction via an AMPK-Dependent Mechanism	12
Acupuncture for Rheumatoid Arthritis Treatment: Biological Mechanisms of Anti-Inflammation and Analgesia	11
Triptolide from Tripterygium wilfordii Suppresses Glycolysis and Induces Cuproptosis via the HK2/DLAT Signaling Pathway in Colorectal Cancer	11
Traditional Chinese Medicine for Cancer Treatment	11
Targeting Autophagy with Geniposide Ameliorates Atherosclerosis in ApoE−∕− Mice	11
Calycosin Enhances Heat Shock Related-Proteins in H9c2 Cells to Modulate Survival and Apoptosis against Heat Shock	11
Bufalin Inhibits Tumorigenesis and SREBP-1-Mediated Lipogenesis in Hepatocellular Carcinoma via Modulating the ATP1A1/CA2 Axis	11
Ferroptosis in Endometriosis: Traditional Chinese Medicine Interventions and Mechanistic Insights	11
Red Yeast Rice and Statin Therapy in Patients with Hypercholesterolemia and the Comorbidities: A Retrospective Cohort Study on Lipid-Lowering Effects and Cardiovascular Outcomes	11
Ginkgo biloba : The Traditional Use, Phytochemistry, Pharmacology, and Therapeutic Applications	10
A Review of Traditional Chinese Medicine for Triple Negative Breast Cancer and the Pharmacological Mechanisms	10
Gut Microbiota Regulation by Acupuncture and Moxibustion: A Systematic Review and Meta-Analysis	10
The Effectiveness of Traditional Chinese Medicine in Treating Malignancies via Regulatory Cell Death Pathways and the Tumor Immune Microenvironment: A Review of Recent Advances	10
The Pharmacology and Toxicology of Ginkgolic Acids: Secondary Metabolites from Ginkgo biloba	10
Osthole, a Coumarin from Cnidium monnieri: A Review on Its Pharmacology, Pharmacokinetics, Safety, and Innovative Drug Delivery Platforms	10
The Effectiveness of Acupuncture for Low Back Pain: An Umbrella Review and Meta-Analysis	10
Paeoniflorin Alleviates Metabolic Dysfunction-Associated Fatty Liver Disease by Targeting STING-Mediated Pyroptosis via Inhibiting the NLRP3 Inflammasome	10
ERRATUM: Paris polyphylla Suppresses Proliferation and Vasculogenic Mimicry of Human Osteosarcoma Cells and Inhibits Tumor Growth	10
Ginsenoside Re Attenuates Cisplatin-Induced Intestinal Toxicity via Suppressing GSK-3β-Dependent Wnt/β-Catenin Signaling Pathway In Vivo and In Vitro	10
Research Progress in Ulcerative Colitis: The Role of Traditional Chinese Medicine on Gut Microbiota and Signaling Pathways	10
Role of Traditional Chinese Medicine in Lung Cancer Management: A Review	10
Curcumol Reduces Aerobic Glycolysis and Overcomes Chemoresistance by Inducing Cdh1-Mediated Skp2 Ubiquitination	10
Astragalus membranaceus Polysaccharide Regulates Small Intestinal Microbes and Activates IL-22 Signal Pathway to Promote Intestinal Stem Cell Regeneration in Aging Mice	10
Amelioration of Lung Fibrosis by Total Flavonoids of Astragalus via Inflammatory Modulation and Epithelium Regeneration	10
A Novel Paradigm Defines Functional Molecule Clusters for an Anti-Alzheimer’s Disease Recipe from Traditional Chinese Medicine	10
Valeriana Jatamansi: An Overview of Phytochemistry, Pharmacology, Clinical Prospects, and Network Analysis of Drug Targets	10
Rutaecarpine Alleviates Early Brain Injury-Induced Inflammatory Response Following Subarachnoid Hemorrhage via SIRT6/NF-κB Pathway	10
Chinese Medicine for Non-Alcoholic Fatty Liver Disease: Targeting Key Signaling Pathways	10
Narciclasine Induces Caspase Cascade Activation and Cell Apoptosis via JNK Signaling in Oral Cancer	10
Eugenol Exerted Significant Anti-Oxidant and Anti-Inflammatory Effects on Experimental Colitis via Directly Acting on PPAR-γ	9
The Role of Traditional Chinese Medicine in the Management of Cervical Cancer	9
Pharmacological Benefits and Underlying Mechanisms of Salvia miltiorrhiza against Molecular Pathology of Various Liver Diseases: A Review	9
Notoginsenoside R1 Ameliorates Myocardial Ischemia/Reperfusion Injury by Suppressing Apoptosis via Activating Wnt/β-Catenin Signaling	9
Cordycepin: A Promising Anticancer Compound from Traditional Chinese Medicine	9
Phytochemical Insights into Panax Genus Metabolites: Evidence-Based Fatigue Intervention via Ethnopharmacological and Biomedical Perspectives	9
Total Saponins of Panax notoginseng Leaves Alleviate Vascular Dementia via the Gut–Brain Axis	9
The Role of Traditional Chinese Medicine in the Management of Nonalcoholic Fatty Liver Disease: Targeting Gut Microbiome	9
Berberine Metabolites Stimulate GLP-1 Secretion by Alleviating Oxidative Stress and Mitochondrial Dysfunction	9

Pharmacological Effects of Licorice ( Glycyrrhiza spp.) and Its Bioactive Constituents: The Perspective of Intestinal Microbiota	9
Ginkgo biloba and Its Chemical Components in the Management of Alzheimer’s Disease	9
A Comprehensive Review of Licorice: The Preparation, Chemical Composition, Bioactivities and Its Applications	8
Efficacy and Safety of Glycyrrhizic Acid in Treatment of Autoimmune Hepatitis	8
Curcumin for the Treatment of Inflammatory Bowel Disease: From Mechanism to Clinic	8
Effects of Resveratrol on Pulmonary Fibrosis via TGF-β/Smad/ERK Signaling Pathway	8
Application of Panax ginseng in the Treatment of Chronic Airway Diseases	8
Anti-Inflammatory and Anti-oxidative Effects of Puerarin in Postmenopausal Cardioprotection: Roles of Akt and Heme Oxygenase-1	8
Acupuncture for Neuropathic Pain: Mechanisms, Clinical Efficacy and Future Perspectives	8
Renoprotective Effect of Isoorientin in Diabetic Nephropathy via Activating Autophagy and Inhibiting the PI3K-AKT-TSC2-mTOR Pathway	8
Apigenin Suppresses Innate Immune Responses and Ameliorates Lipopolysaccharide-Induced Inflammation via Inhibition of STING/IRF3 Pathway	8
The Pharmacological Effects of Gastrodin and the Progress in the Treatment of Neurological Disorders	8
Cannabidiol Reprograms Glucose Metabolism in Colorectal Adenocarcinoma by Targeting HIF-1α/LDHA Pathway	7
Therapeutic Effects of Natural Products in the Treatment of Chronic Diseases: The Role in Regulating KEAP1–NRF2 Pathway	7
Korean Red Ginseng Marc-Derived Gintonin Improves Alzheimer’s Cognitive Dysfunction by Upregulating LPAR1	7
Tumor Immune Regulation by Natural Products: Mechanistic Insights and Therapeutic Potential	7
Effectiveness of Chinese Herbal Medicine in Patients with COVID-19 During the Omicron Wave in Hong Kong: A Retrospective Case-Controlled Study	7
Phycocyanin: Biomedical Activities and Related Mechanisms of Action	7
Study on the Chemical Constituents, Pharmacological Activities, and Clinical Application of Taxus	7
The Role of Chinese Medicine in the Treatment of Chronic Hepatitis B	7
Tanshinone IIA Ameliorates Heart Failure by Inhibiting Ferroptosis via the Sirt1/p53/GPX4 Signaling Pathway	7
Total Flavonoids of Astragalus Inhibit Activated CD4+ T Cells and Regulate Differentiation of Th17/Th1/Treg Cells in Experimental Autoimmune Encephalomyelitis Mice by JAK/STAT and NFκB Signaling Pathw	7
The Role of Traditional Chinese Medicines in the Treatment of Osteoporosis	7
Acupuncture for Fibromyalgia: A Review Based on Multidimensional Evidence	7
Angelica sinensis : Botany, Traditional Uses, Phytochemistry, Pharmacology, Safety, and Applications	7
Maslinic Acid Ameliorates Myocardial Ischemia Reperfusion Injury-Induced Oxidative Stress via Activating Nrf2 and Inhibiting NF-κB Pathways	7
Chinese Herbal Medicine, Alternative or Complementary, for Endometriosis-Associated Pain: A Meta-Analysis	7
Traditional Chinese Medicine in the Treatment of Ulcerative Colitis: From Pharmacokinetics to Personalized Therapy	7
Traditional Chinese Medicine for Alzheimer’s Disease: A Systematic Review and Meta-Analysis	7
Integrated Metabonomic Study on the Relationship between Medicinal Properties and Efficacy ofRehmanniae Radix	7
Review on Processing Methods of Toxic Chinese Materia Medica and the Related Mechanisms of Action	7