Toxicologic Pathology

Papers
(The median citation count of Toxicologic Pathology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Kidney Effects by Alternative Classes of Medicines in Patients and Relationship to Effects in Nonclinical Toxicity Studies109
A Pathologist’s Guide to Non-clinical Safety Assessment of Adoptive Cell Therapy Products74
Toxicity and Local Tolerance of COVID- eVax, a Plasmid DNA Vaccine for SARS-CoV-2, Delivered by Electroporation28
Symmetric Dimethylarginine Is a Sensitive Biomarker of Glomerular Injury in Rats26
Early-Onset Asymptomatic Polypoid Cystitis in Two Adolescent Male Beagle Dogs22
Guide for Combining Primary Tumors for Statistical Analysis in Rodent Carcinogenicity Studies20
Spontaneous Findings in the Reproductive System of Sexually Mature Male Cynomolgus Macaques19
Toxicologic Pathology Forum: Opinion on Interpretive Challenges for Procedure-Related Effects Associated With Direct Central Nervous System Delivery of Oligonucleotides to Rodents, Dogs, and Nonhuman 17
Toxicologic Pathology Forum Opinion: Interpretation of Gliosis in the Brain and Spinal Cord Observed During Nonclinical Safety Studies16
Retraction Notice: “Role of Quercetin in Preventing Thioacetamide-Induced Liver Injury in Rats”14
Toxicologic Pathology Forum: mRNA Vaccine Safety–Separating Fact From Fiction14
Artificial Intelligence in Toxicological Pathology: Quantitative Evaluation of Compound-Induced Follicular Cell Hypertrophy in Rat Thyroid Gland Using Deep Learning Models12
In Utero Exposure to 3,3′,4,4′, 5-Pentachlorobiphenyl Dose-Dependently Induces N-butyl-4-(hydroxybutyl) Nitrosamine in Rats With Urinary Bladder Carcinoma12
Scientific and Regulatory Policy Committee Points to Consider: Proposal and Recommendations to Reduce Euthanasia of Control Nonhuman Primates in Nonclinical Toxicity Studies12
Toxicologic Pathology Forum*: Opinion on Assessing and Communicating Adversity for Implantable Medical Devices11
Hepatic Bile Acid Transporters and Drug-induced Hepatotoxicity10
Society of Toxicologic Pathology Nonhuman Primate Special Interest Group: Idiopathic Femoral Head Chondrolysis in Nonclinical Research Macaques10
Magnitude of Urine Albumin and KIM-1 Changes Can be Used to Differentiate Glomerular Injury From Tubular Injury in Rats10
Scientific and Regulatory Policy Committee Points to Consider for Medical Device Implant Site Evaluation in Nonclinical Studies10
Scientific and Regulatory Policy Committee Points to Consider: Nonclinical Research and Development of In Vivo Gene Therapy Products, Emphasizing Adeno-Associated Virus Vectors10
Difference in the Mechanism of Iron Overload–Enhanced Acute Hepatotoxicity Induced by Thioacetamide and Carbon Tetrachloride in Rats10
Investigation of the Proliferative Potential of FGF21 or FGF19 in Liver-Specific FGFR4-Deficient Mice9
Interpretative Challenges in Animal Studies: Review of Case Studies and Implications for Toxicologic Pathology9
Toxicologic Pathology Forum*: Opinion on the Interpretation of Statistical Significance Testing Results From Anatomic and Clinical Pathology Data in Nonclinical Safety Studies9
Scientific and Regulatory Policy Committee Points to Consider: Sampling, Processing, Evaluation, Interpretation, and Reporting of Test Article-Related Ganglion Pathology for Nonclinical Toxicity Studi9
Organ Weights in Relation to Age and Sex in Cynomolgus Monkeys (Macaca fascicularis)8
Selected Resources for Pathology Evaluation of Nonhuman Primates in Nonclinical Safety Assessment8
Opinion on the Optimal Histologic Evaluation of the Bone Marrow in Nonclinical Toxicity Studies8
Cardiac Rhabdomyoma in Four Göttingen Minipigs7
Virtual Control Groups in Non-clinical Toxicity Studies: Impacts on Toxicologic Clinical Pathology Data Interpretation7
Comparative Impact of Various Fasting Periods on the Welfare of Sprague-Dawley Rats With or Without Supplementation7
Neurofilament Light Chain: A Translational Safety Biomarker for Drug-Induced Peripheral Neurotoxicity7
Identifying Erythrocyte Injury in Toxicology Studies7
Applications of Cell-Based Protein Array Technology to Preclinical Safety Assessment of Biological Products7
Proceedings of the 2022 National Toxicology Program Satellite Symposium6
Toxicologic Pathology Forum: A Roadmap for Building State-of-the-Art Digital Image Data Resources for Toxicologic Pathology in the Pharmaceutical Industry6
Toxicologic Pathology Forum: Tissue Evaluation in Nonclinical Toxicity Studies for Prophylactic Vaccines5
Safety and Performance Evaluation of Su2ura Approximation, a New Suturing Device, in Pigs5
Morphologic Features and Deep Learning–Based Analysis of Canine Spermatogenic Stages5
Possible Cytoprotection of Low Dose Lipopolysaccharide in Rat Thioacetamide-Induced Liver Lesions, Focusing on the Analyses of Hepatic Macrophages and Autophagy5
Deep Learning–Based Segmentation of Morphologically Distinct Rat Hippocampal Reactive Astrocytes After Trimethyltin Exposure5
Idiopathic Aneurysms of the Ascending Aorta in the Mouse and Rat5
Scientific and Regulatory Policy Committee Points to Consider: Biological Sample Retention From Nonclinical Toxicity Studies5
Thank You to Reviewers5
Scientific and Regulatory Policy Committee Best Practices: Recommended (“Best”) Practices for Informed (Non-blinded) Versus Masked (Blinded) Microscopic Evaluation in Animal Toxicity Studies4
Assessing the Carcinogenicity of Vadadustat, an Oral Hypoxia-Inducible Factor Prolyl-4-Hydroxylase Inhibitor, in Rodents4
Brief Synopsis: “Instruction Manual for Juvenile Clinical Pathology”4
Mass Spectrometry Imaging Distinguishes Biliary Toxicants on the Basis of Cellular Distribution4
Bortezomib-Induced Ovarian Toxicity in Mice4
Immunotoxicology From a Pathology Perspective: A Continuing Education Course Presented at the Annual STP Meeting in Baltimore, MD, Held June 16-19, 20244
Toxicologic Pathology Forum: Opinion on Digital Primary Read and Peer Review—Diving Head-First Into the Deep Digital Pool!3
Historical Control Data of Spontaneous Pathological Findings in C57BL/6J Mice Used in 18-Month Dietary Carcinogenicity Assays3
IT/QA and Regulatory Aspects of Digital Pathology: Results of the 8th ESTP International Workshop3
Scientific and Regulatory Policy Committee Points to Consider: Integration of Clinical Pathology Data With Anatomic Pathology Data in Nonclinical Toxicology Studies3
Scientific and Regulatory Policy Committee Technical Review: Biology and Pathology of Ganglia in Animal Species Used for Nonclinical Safety Testing3
Scientific and Regulatory Policy Committee Points to Consider: Fixation, Trimming, and Sectioning of Nonrodent Eyes and Ocular Tissues for Examination in Ocular and General Toxicity Studies3
Historical Control Background Incidence of Spontaneous Neoplastic Lesions of Sprague-Dawley Rats in 104-Week Toxicity Studies3
Neurobiomarkers: Basic Aspects and Their Relevance in Nonclinical Studies3
Effects of LRRK2 Inhibitors in Nonhuman Primates3
Kidney Injury Monitoring in Tobramycin-Treated Rhesus Monkeys: Supplementing Urinary Kidney Biomarkers With Kidney Biopsy Gene Expression Profiling3
Corrigendum to Histology Atlas of the Developing Mouse Placenta3
Toxicologic Pathology Forum: Opinion on Approaches for Reporting Toxic and Adverse Dose Levels in Nonclinical Toxicology Studies Supporting the Development of Anticancer Pharmaceuticals3
Proceedings of the 2021 National Toxicology Program Satellite Symposium3
An Overview of Nonclinical and Clinical Liver Toxicity Associated With AAV Gene Therapy3
The Impact of Functional and Structural Maturation of the Kidney on Susceptibility to Drug and Chemical Toxicity in Neonatal Rodents3
Phthalate Toxicity in Rats and Its Relation to Testicular Dysgenesis Syndrome in Humans3
Case Report: Glioneuronal Hamartoma in the Cerebral Cortex of a Juvenile Cynomolgus Monkey ( Macaca fascicularis )3
Pathological Characterization of Spontaneous AA Amyloidosis in Microminipigs3
Characterization of Urothelial Inclusions in Male Wistar Han Rats Treated Orally With the Novel α2A-Adrenoceptor Agonist Tasipimidine3
A Fandango of Form and Function: The Interplay Between Clinical Neurology and Neuropathology Evaluation2
Results of the European Society of Toxicologic Pathology Survey on the Use of Artificial Intelligence in Toxicologic Pathology2
Proceedings of the 2024 Division of Translational Toxicology Satellite Symposium2
Toxicologic Pathology Forum*: Opinion on Qualitative Severity Descriptors to Express Magnitude of Changes in Clinical Pathology Endpoints in Nonclinical Toxicity Studies2
Session 4: mRNA and Self-Amplifying RNA (saRNA): Opportunities for Disease Prevention and Therapy2
Toxicologic Pathology Forum: Opinion on Digital Primary Read and Peer Review—Are We There Yet?2
Immune-Mediated Liver Effects Associated With Administration of a Human Anti-IL-21 Receptor Antibody (ATR-107) in Rats2
Historical Control Data of Spontaneous Lesions of Laboratory New Zealand White and Dutch Belted Rabbits ( Oryctolagus Cuniculus ) Used in Toxicity Studies2
Early-Onset albuminuria and Associated Renal Pathology in Leucine-Rich Repeat Kinase 2 Knockout Rats2
Complex In Vitro Model Characterization for Context of Use in Toxicologic Pathology: Use Cases by Collaborative Teams of Biologists, Bioengineers, and Pathologists2
Considerations for the Identification and Conveyance of Clinical Pathology Findings in Preclinical Toxicity Studies: Results From the 9th ESTP International Expert Workshop2
Does Geographical Origin of Long-Tailed Macaques (Macaca fascicularis) Matter in Drug Safety Assessment?: A Literature Review and Proposed Conclusion2
Regulatory Perspectives on Juvenile Animal Toxicologic Pathology2
Granulocytosis, a Paraneoplastic Syndrome Associated With Non-Glandular Squamous Cell Carcinomas (NGSCC) in the Tg.rasH2 Studies2
Special Issue on the Pathobiology of Laboratory Nonhuman Primates: A Review of Species, Substrain, Geographical Origin, Age, and Modality-Related Factors2
Post-Pandemic Pathology Practice2
Histology Atlas of the Developing Mouse Respiratory System From Prenatal Day 9.0 Through Postnatal Day 302
Immunohistochemical Characterization of Proliferative Lesions in the Thymus of Aging CD-1 Mice From Two Studies on the RITA Database, With Special Reference to the Perivascular Space2
Society of Toxicologic Pathology Neuropathology Interest Group Article: Neuropathologic Findings in Nonhuman Primates Associated With Administration of Biomolecule-Based Test Articles2
Proceedings of the 2023 Annual Scientific Meeting of the French Society of Toxicologic Pathology (SFPT) on Preclinical Development and Therapeutic Applications of mRNA-Based Technologies2
Neuropathology Evaluation in Juvenile Toxicity Studies in Rodents: Comparison of Developmental Neurotoxicity Studies for Chemicals With Juvenile Animal Studies for Pediatric Pharmaceuticals2
Points to Consider From the ESTP Pathology 2.0 Working Group: Overview on Spatial Omics Technologies Supporting Drug Discovery and Development2
How Does Lifestyle Affect Hematopoiesis and the Bone Marrow Microenvironment?2
Spontaneous Primary Pleural Mesothelioma in Fischer 344 (F344) and Other Rat Strains: A Retrospective Review2
Use of Both Fluoro-Jade B and Hematoxylin and Eosin to Detect Cell Death in the Juvenile Rat Brain Exposed to NMDA-Receptor Antagonists or GABA-Receptor Agonists in Safety Assessment2
Toxicologic Pathology Forum*: Opinion on New Technologies and Trends Disrupting Drug Discovery and Development: How Can the Next Generation of Toxicologic Pathologists Be Prepared for Evolving Roles?2
To Clot or Not to Clot: Deepening Our Understanding of Alterations in the Hemostatic System2
Prenatal Evaluations: A Prologue to Postnatal Pathology Interpretations2
2024 International Academy of Toxicologic Pathology (IATP) Satellite Symposium: New Approach Methodologies (NAMs) for Neurotoxicity Assessment and Regulatory Perspectives2
Nervous System Sampling for General Toxicity and Neurotoxicity Studies in the Laboratory Minipig With Emphasis on the Göttingen Minipig2
Chronic Inhalation Exposure to Antimony Trioxide Exacerbates the MAPK Signaling in Alveolar Bronchiolar Carcinomas in B6C3F1/N Mice2
Pseudoreticulocytosis by the ADVIA 2120 Hematology Analyzer and Other Hematologic Changes in a Cynomolgus Macaque (Macaca fascicularis) With Malaria1
Molecular Pathology Methods to Characterize Biodistribution and Pharmacodynamics of the Oncolytic Virus VSV-GP in a Nonclinical Tumor Model1
Corrigendum to Toxicologic Pathology Forum: Opinion on Performing Good Laboratory Practice Histopathology Evaluation for Nonclinical Toxicity Studies in a Remote Location1
Obituary: Dr Gordon Charles Hard (1931-2021)1
IHI VICT3R: Developing and Implementing Virtual Control Groups to Reduce Animal Use in Toxicology Research1
Assessment of Color Reproducibility and Mitigation of Color Variation in Whole Slide Image Scanners for Toxicologic Pathology1
A Developmental Atlas as a Reflection of Our Professional Lifecycle1
Pathology Findings and In-Life Correlates in the Nonclinical Development of Adeno-Associated Virus (AAV)-Based Retinal Gene Therapies1
Session 5: Protein Degraders1
Book Review: Toxicologic Pathology for Non-Pathologists1
Thyroid Hormone Imbalance in Pregnant Rats and its Impact on Neurodevelopment in Pups: A Minireview on Histopathological Endpoints1
Safety, Tissue Distribution, and Metabolism of LNA-Containing Antisense Oligonucleotides in Rats1
Toxicologic Pathology Forum Opinion Piece: Use of Virtual Control Groups in Nonclinical Toxicity Studies: The Anatomic Pathology Perspective1
Risk Assessment for Hepatobiliary Toxicity Liabilities in Drug Development1
Scientific and Regulatory Policy Committee Brief Communication: 2019 Survey on Use of Digital Histopathology Systems in Nonclinical Toxicology Studies1
Exogenous Growth Hormone Exacerbates Post-Irradiation Atherosclerosis in Susceptible Epicardial Coronary Arteries1
Extraintestinal Pathogenic Escherichia Coli Causes Necrohemorrhagic Pneumonia in Multiple Research Dogs1
Common and Not-So-Common Pathologic Findings of the Gastrointestinal Tract of Rhesus and Cynomolgus Macaques1
Neutropenia in Cynomolgus Monkeys With Anti-Drug Antibodies Associated With Administration of Afucosylated Humanized Monoclonal Antibodies1
Deep Learning–Based Spermatogenic Staging in Tissue Sections of Cynomolgus Macaque Testes1
Myelin Methods: A Mini-Review1
Histology Atlas of the Developing Mouse Placenta1
Poster Abstracts of the 20th Congress of the European Society of Toxicologic Pathology (Basel, Switzerland, 26th - 29th of September 2023, Emerging Therapeutic Modalities)1
Neurodegenerative Diseases: Pathogenesis and Preclinical Models for Translational Drug Discovery1
Toxicogenomics Approaches to Address Toxicity and Carcinogenicity in the Liver1
Pathology of Bone: Changes Associated With Different Classes of Compounds1
Comparison of ANP and BNP Granular Density in Atria of Rats After Physiological and Pathological Hypertrophy1
Carcinogenicity Evaluation of Baclofen in TgrasH2 Mice1
Applications of Molecular Pathology: An Evolving Approach to Toxicologic Pathology1
Gastric Neuroendocrine Tumors With Parietal Cell Atrophy in a Long-term Carcinogenicity Study in Rats1
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