Toxicologic Pathology

Papers
(The TQCC of Toxicologic Pathology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Guide for Combining Primary Tumors for Statistical Analysis in Rodent Carcinogenicity Studies47
Thymic Epithelial Hyperplasia and Thymoma in Control rasH2 Transgenic Mice From 26-Week Carcinogenicity Assays36
Kidney Effects by Alternative Classes of Medicines in Patients and Relationship to Effects in Nonclinical Toxicity Studies28
A Pathologist’s Guide to Non-clinical Safety Assessment of Adoptive Cell Therapy Products24
Early-Onset Asymptomatic Polypoid Cystitis in Two Adolescent Male Beagle Dogs24
Toxicologic Pathology Forum: Opinion on Interpretive Challenges for Procedure-Related Effects Associated With Direct Central Nervous System Delivery of Oligonucleotides to Rodents, Dogs, and Nonhuman 20
Toxicologic Pathology Forum Opinion: Interpretation of Gliosis in the Brain and Spinal Cord Observed During Nonclinical Safety Studies18
Comparative Study of Chemically Induced Renal Mesenchymal and Mammary Tumors in Female Sprague-Dawley and Wistar Rats16
Toxicologic Pathology Forum*: Opinion on Assessing and Communicating Adversity for Implantable Medical Devices16
Toxicologic Pathology Forum: mRNA Vaccine Safety–Separating Fact From Fiction15
Retraction Notice: “Role of Quercetin in Preventing Thioacetamide-Induced Liver Injury in Rats”14
Scientific and Regulatory Policy Committee Points to Consider: Proposal and Recommendations to Reduce Euthanasia of Control Nonhuman Primates in Nonclinical Toxicity Studies13
Magnitude of Urine Albumin and KIM-1 Changes Can be Used to Differentiate Glomerular Injury From Tubular Injury in Rats13
Neuro Omics: Translational Neuropathology Applications of Spatial Technologies From Nonclinical Models to Human Disease13
Scientific and Regulatory Policy Committee Points to Consider for Medical Device Implant Site Evaluation in Nonclinical Studies12
Hepatic Bile Acid Transporters and Drug-induced Hepatotoxicity11
Difference in the Mechanism of Iron Overload–Enhanced Acute Hepatotoxicity Induced by Thioacetamide and Carbon Tetrachloride in Rats11
Spontaneous Abdominal Hemangiosarcoma With Metastases to the Lungs in a Control Sprague-Dawley Rat11
Interpretative Challenges in Animal Studies: Review of Case Studies and Implications for Toxicologic Pathology11
Scientific and Regulatory Policy Committee Points to Consider: Sampling, Processing, Evaluation, Interpretation, and Reporting of Test Article-Related Ganglion Pathology for Nonclinical Toxicity Studi9
Investigation of the Proliferative Potential of FGF21 or FGF19 in Liver-Specific FGFR4-Deficient Mice9
Toxicologic Pathology Forum*: Opinion on the Interpretation of Statistical Significance Testing Results From Anatomic and Clinical Pathology Data in Nonclinical Safety Studies9
Oligonucleotides: Evolution of Carcinogenicity and Risk Assessment Strategy8
Comparative Impact of Various Fasting Periods on the Welfare of Sprague-Dawley Rats With or Without Supplementation8
Scientific and Regulatory Policy Committee Points to Consider*: Sample Selection, Assay Design, Data Generation and Interpretation, and Reporting Practices for Chromogenic Immunohistochemical (IHC) As8
Navigating the Pathology Minefield: Harnessing the Value of Historical Control Data in Rodent Carcinogenicity Studies8
Virtual Control Groups in Non-clinical Toxicity Studies: Impacts on Toxicologic Clinical Pathology Data Interpretation8
Cardiac Rhabdomyoma in Four Göttingen Minipigs8
Applications of Cell-Based Protein Array Technology to Preclinical Safety Assessment of Biological Products7
Proceedings of the 2024 Classic Examples in Toxicologic Pathology XXXI7
Identifying Erythrocyte Injury in Toxicology Studies7
Thank You to Reviewers7
Transmission Electron Microscopy of the Peripheral Nervous System: Methods, Sample Preparation, and Case Studies7
Toxicologic Pathology Forum: A Roadmap for Building State-of-the-Art Digital Image Data Resources for Toxicologic Pathology in the Pharmaceutical Industry7
Neurofilament Light Chain: A Translational Safety Biomarker for Drug-Induced Peripheral Neurotoxicity7
Pathophysiology of Ischemic Cell Death in the Central Nervous System7
Deep Learning–Based Segmentation of Morphologically Distinct Rat Hippocampal Reactive Astrocytes After Trimethyltin Exposure6
Morphologic Features and Deep Learning–Based Analysis of Canine Spermatogenic Stages6
Toxicologic Pathology Forum: Tissue Evaluation in Nonclinical Toxicity Studies for Prophylactic Vaccines6
Proceedings of the 2022 National Toxicology Program Satellite Symposium6
Immunotoxicology From a Pathology Perspective: A Continuing Education Course Presented at the Annual STP Meeting in Baltimore, MD, Held June 16-19, 20246
Deep Learning Methodology for Quantification of Normal Pancreas Structures6
Neurobiomarkers: Basic Aspects and Their Relevance in Nonclinical Studies6
An Overview of Nonclinical and Clinical Liver Toxicity Associated With AAV Gene Therapy6
Scientific and Regulatory Policy Committee Points to Consider: Integration of Clinical Pathology Data With Anatomic Pathology Data in Nonclinical Toxicology Studies5
Reliable Identification of Alpha2u-Globulin and Lysozyme Accumulation in Rat Kidney by Label-Free MALDI Mass Spectrometry Imaging5
Scientific and Regulatory Policy Committee Best Practices: Recommended (“Best”) Practices for Informed (Non-blinded) Versus Masked (Blinded) Microscopic Evaluation in Animal Toxicity Studies5
Assessing the Carcinogenicity of Vadadustat, an Oral Hypoxia-Inducible Factor Prolyl-4-Hydroxylase Inhibitor, in Rodents5
Case Report: Glioneuronal Hamartoma in the Cerebral Cortex of a Juvenile Cynomolgus Monkey ( Macaca fascicularis )5
Mass Spectrometry Imaging Distinguishes Biliary Toxicants on the Basis of Cellular Distribution5
Toxicologic Pathology Forum: Opinion on Digital Primary Read and Peer Review—Diving Head-First Into the Deep Digital Pool!4
Historical Control Data of Spontaneous Pathological Findings in C57BL/6J Mice Used in 18-Month Dietary Carcinogenicity Assays4
Toxicologic Pathology Forum*: Opinion on New Technologies and Trends Disrupting Drug Discovery and Development: How Can the Next Generation of Toxicologic Pathologists Be Prepared for Evolving Roles?4
Toxicologic Pathology Forum*: Opinion on the Future of Histopathology Using Whole Slide Images in Toxicologic Pathology of Preclinical Studies and Its Successful Implementation in Compliance With Good4
Corrigendum to Histology Atlas of the Developing Mouse Placenta4
Effects of LRRK2 Inhibitors in Nonhuman Primates4
IT/QA and Regulatory Aspects of Digital Pathology: Results of the 8th ESTP International Workshop4
Red Deads, Ghosts, and the Afterlife: A Guide to Neuronal Cell Death4
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