Peptides

Article	Citations
Transcardiac gradients of pro-cholecystokinin, cholecystokinin, and gastrin in patients with and without heart failure with reduced ejection fraction	106
Corrigendum to “Oxytocin attenuates cardiac hypertrophy by improving cardiac glucose metabolism and regulating OXTR/JAK2/STAT3 axis” [Peptides 182 (2024) 171323]	85
Editorial Board	82
Editorial Board	44
KNDy neurons as the GnRH pulse generator: Recent studies in ruminants	39
Serum alanine transaminase is predictive of fasting and postprandial insulin and glucagon concentrations in type 2 diabetes	39
The first structure-activity relationship study of oxytocin as a positive allosteric modulator for the µ opioid receptor	37
PCP consensus protein/peptide alphavirus antigens stimulate broad spectrum neutralizing antibodies	36
The present and future of synthetic orexin receptor agonists	33
Emerging roles of oxyntomodulin-based glucagon-like peptide-1/glucagon co-agonist analogs in diabetes and obesity	32
Natriuretic peptides potentiate cardiac hypertrophic response to noradrenaline in rats	31
Angiotensin-(1−7), a protective peptide against vascular aging	27
Desacyl-ghrelin, not just an inactive form of ghrelin? A review of current knowledge on the biological actions of desacyl-ghrelin	26
Minimum biological domain of xenin-25 required to induce anion secretion in the rat ileum	25
The antimicrobial peptide Abaecin alleviates colitis in mice by regulating inflammatory signaling pathways and intestinal microbial composition	24
Gut hormone analogues and skeletal health in diabetes and obesity: Evidence from preclinical models	24
Nesfatin-1 regulates steroidogenesis in mouse Leydig cells	24
Localization and expression of Orexin B (OXB) and its type 2 receptor (OX2R) in mouse testis during postnatal development	23
The impact of multifunctional enkephalin analogs and morphine on the protein changes in crude membrane fractions isolated from the rat brain cortex and hippocampus	23
Peptides and primate personality: Central and peripheral oxytocin and vasopressin levels and social behavior in two baboon species (Papio hamadryas and Papio anubis)	23
Editorial Board	22
Asprosin-mediated regulation of ovarian functions in mice: An age-dependent study	21
Studies on the in vitro mechanism and in vivo therapeutic effect of the antimicrobial peptide ACP5 against Trichophyton mentagrophytes	21
Editorial Board	21
Effect of Fc-Elabela-21 on renal ischemia/reperfusion injury in mice: Mediation of anti-apoptotic effect via Akt phosphorylation	21

Editorial Board	20
Suppression of B-type natriuretic peptide gene expression in cardiomyocytes under anoxic conditions	19
Synthesis, conformation and cytotoxic activity of short hybrid peptides containing conformationally constrained 1-(aminomethyl)cyclohexanecarboxylic acid and gabapentin	19
Impact of galanin receptors 2 and 3 double-knockout on neuroinflammation and functional recovery following traumatic brain injury	19
VR-10 polypeptide interacts with CD36 to induce cell apoptosis and autophagy in choroid-retinal endothelial cells: Identification of VR-10 as putative novel therapeutic agent for choroid neovasculariz	18
GIP-derived GIP receptor antagonists – a review of their role in GIP receptor pharmacology	18
Endogenous opiates and behavior: 2024	18
Glucagon-like peptide-1 receptor promotes osteoblast differentiation of dental pulp stem cells and bone formation in a zebrafish scale regeneration model	18
Modulatory role of neuropeptide FF system in macrophages	18
Editorial Board	17
Lasso peptides realm: Insights and applications	17
Dysfunction of the renin-angiotensin-aldosterone system in human septic shock	17
Dulaglutide accelerates diabetic wound healing by suppressing Nrf2-dependent ferroptosis in diabetic mice	17
Special issue on Invertebrate Peptides	16
JHP-7 (QLLEELKR), a heptapeptide derived from Jinhua ham, may ameliorate intrauterine adhesion (IUA) via inhibiting inflammatory response and apoptosis	16
Allatotropin (AT) related peptides L-ATRP and D2-ATRP diastereomers activate an endogenous receptor and suppress heart rate in the Pacific abalone Haliotis discus hannai	16
Jan Fahrenkrug (6/6 1947 – 10/11 2021)	15
Inhibitors of the MAPK/ NF-κB pathway attenuate the upregulation of the ETB receptor mediated by high glucose in vascular smooth muscle cells	15
Recombinant production of isotope-labeled human α-defensin 5 via calmodulin fusion and insights into its expression enhancement	14
Influence of the angiotensin-(1−7) on the vascular effects of the endothelin-1 in normotensive and hypertensive rats	14
Simplified drug efficacy evaluation system for vasopressin neurodegenerative disease using mouse disease-specific induced pluripotent stem cells	14
Endogenous opiates and behavior: 2023	14
Glucagon and energy expenditure; Revisiting amino acid metabolism and implications for weight loss therapy	14
The intricate relationship between circadian rhythms and gastrointestinal peptides in obesity	14
Significance of D- tryptophan in Contryphan-Ar1131 Conus peptide: Oxidative folding, trypsin binding, and photostabilization activity	14
The role of leptin and ghrelin in the regulation of appetite in obesity	14
A novel endomorphin-2/salmon calcitonin hybrid peptide with enhancing anti-allodynic and anti-anxiety effects	14
Erythropoietin attenuates lead-induced spatial memory deficits and anxiety-like behavior by suppressing hippocampal oxidative stress, cell death inhibition, and inflammation reduction	14
Peptides as mediators of stress responses	13
The T-1 conotoxin μ-SrVA from the worm hunting marine snail Conus spurius preferentially blocks the human NaV1.5 channel	13
Glucagon-based therapy for people with diabetes and obesity: What is the sweet spot?	13
Targeting the GLP-2 receptor in the management of obesity	13
Reduced plasma cortistatin is related to clinical parameters in patients with essential hypertension	13
PACAP inhibits sepsis-associated acute lung injury by inhibiting the Sp1/AQP1 pathway	13
Investigation of irisin's role in pubertal onset physiology in female rats	13
Venomous gland transcriptome and venom proteomic analysis of the scorpion Androctonus amoreuxi reveal new peptides with anti-SARS-CoV-2 activity	13
Editorial Board	13
Synthesis of potent antagonists of receptors for growth hormone-releasing hormone with antitumor and anti-inflammatory activity	13
Development of a glucagon sensitivity test in humans: Pilot data and the GLUSENTIC study protocol	13
Body weight modulates the impact of oxytocin on chronic cold-immobilization stress response	12
Editorial: Special issue novel aspects of islet peptides	12
Liraglutide suppresses ferroptosis by upregulation NRF2 in type 2 diabetic cardiomyopathy	12
Effectiveness of analog of Humanin in ameliorating streptozotocin-induced diabetic nephropathy in Sprague Dawley rats	12
Corrigendum to “Liraglutide inhibited AGEs induced coronary smooth muscle cell phenotypic transition through inhibiting the NF-κB signal pathway” [Peptides 112 (2019) 125–132]	12
The apelin-apela receptor APJ is necessary for formation and healing of ischemia reperfusion-induced gastric ulcer in rats	12
Effect of pregnancy on the expression of nutrient-sensors and satiety hormones in mice	12
Estrogens impair hypophagia and hypothalamic cell activation induced by vasoactive intestinal peptide, but not by pituitary adenylate cyclase-activating polypeptide	11
GLP-1 and GIP receptor signaling in beta cells – A review of receptor interactions and co-stimulation	11
Semaglutide early intervention attenuated testicular dysfunction by targeting the GLP-1–PPAR-α–Kisspeptin–Steroidogenesis signaling pathway in a testicular ischemia-reperfusion rat model	11
Urocortin3: Local inducer of somatostatin release and bellwether of beta cell maturity	11

Role of brain NUCB2/nesfatin-1 in stress and stress-related gastrointestinal disorders	11
Alamandine attenuates oxidative stress in the right carotid following transverse aortic constriction in mice	11
Egg white-derived peptide KPHAEVVLR promotes wound healing in rat palatal mucosa via PI3K/AKT/mTOR pathway	11
The effects of corticotropin-releasing factor (CRF) and urocortins on the noradrenaline (NA) released from the locus coeruleus (LC)	11
The non-cardiovascular actions of ACE	11
Neuropeptides affecting social behavior in mammals: Oxytocin	11
Spexin expression in the human bile duct and perihilar cholangiocarcinoma	11
Corticotropin-releasing factor receptor 1 (CRF-R1) antagonists: Promising agents to prevent visceral hypersensitivity in irritable bowel syndrome	10
FGF4 alleviates renal injury caused by ischemia-reperfusion(I/R) by inhibiting ferroptosis and pyroptosis	10
Angiotensin-(1−7) attenuates the negative inotropic response to acetylcholine in the heart	10
Editorial Board	10
Synergistic interaction between DAMGO-NH2 and NOP01 in peripherally acting antinociception in two mouse models of formalin pain	10
Angiotensin-(1-7) reduces doxorubicin-induced aortic arch dysfunction in male and female juvenile Sprague Dawley rats through pleiotropic mechanisms	10
Characterization of rice endosperm-derived antidepressant-like peptide (REAP): An orally active novel tridecapeptide derived from rice protein	10
Recent articles highlighting the multifunctional character and wider therapeutic potential of antimicrobial peptides	10
Maximizing cost savings in heart failure management: The economic value of natriuretic peptide testing	10
Editorial Board	10
In memoriam: Dr. Stephen Tobe (11 October 1944 – 31 December 2020)	10
Irisin alleviates hyperoxia-induced bronchopulmonary dysplasia through activation of Nrf2/HO-1 pathway	10
Editorial Board	9
Protective effects of PACAP against high glucose-induced inflammation on air-liquid interface corneal epithelium barrier	9
Nesfatin-1 is involved in hyperbaric oxygen-mediated therapeutic effects in high fat diet-induced hyperphagia in mice	9
Interleukin-6, undercarboxylated osteocalcin, and brain-derived neurotrophic factor responses to single and repeated sessions of high-intensity interval exercise	9
Engineering a potent and long-acting GLP-1/Y2 receptor dual agonist as a multi-agonist therapy for diabetes and obesity	9
Irisin prevents hypoxic-ischemic brain damage in rats by inhibiting oxidative stress and protecting the blood-brain barrier	9
AT2 receptor agonist LP2 restores respiratory function in a rat model of bleomycin-induced lung remodelling	9
Structure and function of neurohypophysial hormones	9
Role of sexually dimorphic oxytocin receptor-expressing neurons in the anteroventral periventricular nucleus on maternal behavior	9
GLP-1 receptor agonism and GIP receptor antagonism induce substantial alterations in enteroendocrine and islet cell populations in obese high fat fed mice	9
Involvement of relaxin-family peptide-3 receptor (RXFP3) in the ventral dentate gyrus of the hippocampus in spatial and fear memory in rats	8
A short framework-III (mini-M-2) conotoxin from the venom of a vermivorous species, Conus archon, inhibits human neuronal nicotinic acetylcholine receptors	8
Host defense peptides at the crossroad of endothelial cell physiology: Insight into mechanistic and pharmacological implications	8
PD1 CD44 antiviral peptide as an inhibitor of the protein-protein interaction in dengue virus invasion	8
Functional role of immunoglobulin G as an oxytocin-carrier protein	8
Discovery of the bioactive form of glucagon-like peptide-1: An attempt to correct some misconceptions	8
The impact of GLP-1 signalling on the energy metabolism of pancreatic islet β-cells and extrapancreatic tissues	8
History of peptide research: Ulf Svante von Euler's last visit to Yugoslavia	7
Amphibian host-defense peptides with potential for Type 2 diabetes therapy – an updated review	7
Antiosteoporosis effects of a marine antimicrobial peptide pardaxin via regulation of the osteogenesis pathway	7
Evaluation of plasma arginine vasopressin during hypertonic saline loading: A comparison of radioimmunoassay and liquid chromatography–tandem mass spectrometry	7
Neprilysin deficiency reduces hepatic gluconeogenesis in high fat-fed mice	7
Diminazene Aceturate, an angiotensin converting enzyme 2 (ACE2) activator, promotes cardioprotection in ischemia/reperfusion-induced cardiac injury	7
Mitochondrial-derived peptides: Antidiabetic functions and evolutionary perspectives	7
Cbf-14, a cationic peptide derived from cathelin-domain, exhibits anti-inflammation activity via inhibiting PI3K- Akt /ROS/ NF-κB signaling pathway	7
LP2, a cyclic angiotensin-(1−7) analog extended with an N-terminal D-lysine, impairs growth of patient-derived xenografts of colorectal carcinoma in mice	7
Optogenetics studies of kisspeptin neurons	7
Peptides in the regulation of glucagon secretion	7
Adropin: A cardio-metabolic hormone in the periphery, a neurohormone in the brain?	7
Gluco-metabolic response to exogenous oxytocin in totally pancreatectomized patients and healthy individuals	7
Abba J. Kastin – Tribute to the founding and honorary editor of PEPTIDES	7
Development of antimicrobial peptides as a strategy for infectious disease control	7
Acute effects of peripherally administered nicotine on food intake via the central anorectic peptide nesfatin-1/nucleobindin-2 in adult male rats	7
Heart peptides and HFpEF (heart failure with preserved ejection fraction)	7
Post-prandial secretion of glucagon-like peptide-2 (GLP-2) after carbohydrate-, fat- or protein enriched meals in healthy subjects	7
Vasoactive intestinal peptide receptor 2 signaling promotes breast cancer cell proliferation by enhancing the ERK pathway	7
Publishing in PEPTIDES − A 2022 update	6
Autonomic control of pancreatic beta cells: What is known on the regulation of insulin secretion and beta-cell proliferation in rodents and humans	6
Phoenixin-14 ameliorates acetic acid-induced ulcerative colitis in rats via antioxidant, anti-inflammatory and anti-apoptotic mechanisms	6
Therapeutic potential of vasopressin in the treatment of neurological disorders	6
Editorial Board	6
The role of intraamygdaloid oxytocin in spatial learning and avoidance learning	6
The dual incretin co-agonist tirzepatide increases both insulin secretion and glucose effectiveness in model experiments in mice	6
A murine model of obesity with hyperinsulinemia and hepatic steatosis involving neurosecretory protein GL gene and a low-fat/medium-sucrose diet	6
Synthesis and characterization of piperic acid conjugates with homochiral and heterochiral dipeptides containing phenylalanine and their application in skin cancer	6
The regulatory role of central neuropeptide-S in locomotion	6
Gap junction coupling and islet delta-cell function in health and disease	6
Exploring the role of glycoprotein hormone GPA2/GPB5 in the medically important insect, Rhodnius prolixus	6
The circular bacteriocin enterocin NKR-5-3B has an improved stability profile over nisin	6
Vascular endothelial cell-specific overexpression of CNP did not improve liver fibrosis in HFFCD-induced NASH, but did improve renal lesions	6
Identification and utility exploration of a highly potent and long-acting bullfrog GLP-1 analogue in GLP-1 and amylin combination therapy	6
Irisin lowers blood pressure in Zucker diabetic rats by regulating the functions of renal angiotensin II type 1 receptor via the inhibition of the NF-κB signaling pathway	6
Discovery of novel OXM-based glucagon-like peptide 1 (GLP-1)/glucagon receptor dual agonists	6
Viktor Mutt lecture: Peptides can cross the blood-brain barrier	6
Orexin deficiency modulates the dipsogenic effects of angiotensin II in a sex-dependent manner	6
Corrination mitigates peptide aggregation as exemplified for Glucagon	6
Cardiovascular peptide hormones – Special edition	6
Protective effect of pituitary adenylate cyclase activating polypeptide in diabetic keratopathy	6
Corrigendum to “Cyclopeptide Dmt-[D-Lys-p-CF3-Phe-Phe-Asp]NH2, a novel G protein-biased agonist of the mu opioid receptor” [Peptides 101 (2018) 227–233]	5
Arterial responses to infusion of glucagon-like peptide-1 in humans: A randomized trial study	5
Glucagon-like Peptide 1 Receptor Agonist use and the effect on diabetic retinopathy: An uncertain relationship	5

Interactions between nesfatin-1 and the autonomic nervous system—An overview	5
Editorial Board	5
Molecular and functional characterization of the luqin-type neuropeptide signaling system in the sea cucumber Apostichopus japonicus	5
Peptide‑based therapeutic strategies for glioma: Current state and prospects	5
Computer vision analysis of mother-infant interaction identified efficient pup retrieval in V1b receptor knockout mice	5
Tachykinins amplify the action of capsaicin on central histaminergic neurons	5
Overexpressed beta cell CART increases insulin secretion in mouse models of insulin resistance and diabetes	5
Tirzepatide protects against doxorubicin-induced cardiotoxicity by inhibiting oxidative stress and inflammation via PI3K/Akt signaling	5
Neuropeptide S promotes maintenance of newly formed dendritic spines and performance improvement after motor learning in mice	5
Editorial Board	5
The hypothalamic neuropeptide, QRFP, regulates high fat diet intake in female Long-Evans rats following ovariectomy	5
Cm-p5, a molluscan-derived antifungal peptide exerts its activity by a membrane surface covering in a non-penetrating mode	5
Oxytocin ameliorates KCC2 decrease induced by oral bacteria-derived LPS that affect rat primary cultured cells and PC-12 cells	5
Nesfatin-1 peptide protects rat renal epithelial cells against high glucose and H2O2 induced injury via inhibition of oxidative stress, apoptosis, and fibrosis	5
ACE2 suppresses the inflammatory response in LPS-induced porcine intestinal epithelial cells via regulating the NF-κB and MAPK pathways	5
Corrigendum to “Chronic catestatin treatment reduces atrial fibrillation susceptibility via improving calcium handling in post-infarction heart failure rats” Peptide 159(2023) 170904	5
Editorial Board	5
EPI-X4, a CXCR4 antagonist inhibits tumor growth in pancreatic cancer and lymphoma models	5
Editorial Board	5
Elevated Plasma Soluble (Pro)renin receptor as a potential indicator for heart failure	5
Chronic exposure to incretin metabolites GLP-1(9−36) and GIP(3−42) affect islet morphology and beta cell health in high fat fed mice	5
Recent advances in peptide-based therapies for obesity and type 2 diabetes	5
Introduction to special issue on feeding peptides	5
Antioxidant and immunomodulatory potency of Lacticaseibacillus rhamnosus NCDC24 fermented milk-derived peptides: A computationally guided in-vitro and ex-vivo investigation	4
Is the efficacy of oxytocin for autism diminished at higher dosages or repeated doses?: Potential mechanisms and candidate solutions	4
Mechanical stretch improves high glucose-induced leptin resistance thus promoting glucose uptake of C2C12 myoblasts	4
Editorial Board	4
Caloxin-derived peptides for the inhibition of plasma membrane calcium ATPases	4
PACAP-ADNP axis prevents outer retinal barrier breakdown and choroidal neovascularization by interfering with VEGF secreted from retinal pigmented epitelium cells	4
Substance P promote macrophage M2 polarization to attenuate secondary lymphedema by regulating NF-kB/NLRP3 signaling pathway	4
Intestinal expression profiles and hepatic expression of LEAP2, ghrelin and their common receptor, GHSR, in humans	4
Retraction notice to “Protective effects of ghrelin on cisplatin-induced nephrotoxicity in mice” [Peptides 82 (2016) 85–91]	4
The angiotensin AT2-receptor agonist compound 21 is an antagonist for the thromboxane TP-receptor – Implications for preclinical studies and future clinical use	4
The renin-angiotensin system and cardiovascular autonomic control in aging	4
Expression patterns and behavioral effects of conopressin and APGWamide in the nudibranch Berghia stephanieae	4
Multiple roles of apelin/APJ system in eye diseases	4
Oxytocin attenuates cardiac hypertrophy by improving cardiac glucose metabolism and regulating OXTR/JAK2/STAT3 axis	4
Immunoneutralization of human angiotensin-(1-12) with a monoclonal antibody in a humanized model of hypertension	4
A novel functional peptide, named EQ-9 (ESETRILLQ), identified by virtual screening from regenerative cell secretome and its potential anti-aging and restoration effects in topical applications	4
Central injection of neuropeptide B induces luteinizing hormone release in male and female rats	4
Mas receptor blockade impairs exercise-induced cardiac hypertrophy	4
Editorial Board	4
Compensatory mechanisms underlying arginine vasopressin regulation in transient polyuria during pregnancy	4
The plant defensins PaDef and γ-thionin inhibit the endothelial cell response to VEGF	4
An update on galanin and spexin and their potential for the treatment of type 2 diabetes and related metabolic disorders	4
Correlation Between decreased mixed venous oxygen saturation and increased B-type natriuretic peptides independent of hemodynamics in pre-heart failure/heart failure patients	4
Roles of Angiotensin III in the brain and periphery	3
Dimerization of hub protein DYNLL1 and bZIP transcription factor CREB3L1 enhances transcriptional activation of CREB3L1 target genes like arginine vasopressin	3
Editorial Board	3
Crosstalk between incretin hormones, Th17 and Treg cells in inflammatory diseases	3
Maternal separation alters peripheral immune responses associated with IFN-γ and OT in mice	3
Editorial: Autonomic regulation of enteroendocrine peptides in health and diseases	3
Pain modulation by oxytocin	3
C1q/TNF-related protein 3 alleviates heart failure via attenuation of oxidative stress in myocardial infarction rats	3
In memoriam - Patrick Robberecht (1944–2023)	3
Duodenal enteroendocrine cells and GIP as treatment targets for obesity and type 2 diabetes	3
Altering Specificity and Enhancing Stability of the Antimicrobial Peptides Nisin and Rombocin through Dehydrated Amino Acid Residue Engineering	3
The semenogelin I-derived peptide SgI-52 in seminal plasma participates in sperm selection and clearance by macrophages	3
2020 Invertebrate Neuropeptide Award Announcement	3
Antimicrobial-wound healing peptides: Dual-function molecules for the treatment of skin injuries	3
Intranasal oxytocin as a treatment for anxiety and autism: From subclinical to clinical applications	3
R150S mutation in the human oxytocin receptor: Gain-of-function effects and implication in autism spectrum disorder	3
The role of spexin in energy metabolism	3
Prolactin-induced neuroprotection against excitotoxicity is mediated via PI3K/AKT and GSK3β/NF-κB in primary cultures of hippocampal neurons	3
Kisspeptin and mammalian reproduction	3
Alamandine: A promising treatment for fibrosis	3
Irisin alleviates high glucose-induced hypertrophy in H9c2 cardiomyoblasts by inhibiting endoplasmic reticulum stress	3
The Viktor Mutt Award Lecture 2024 to Tomas Hökfelt	3
The Mas agonist CGEN-856S prevents Ang II induced cardiomyocyte hypertrophy via nitric oxide production	3
DR8 (DHNNPQIR), a rapeseed-derived peptide, mitigates fibrosis and muscle atrophy in chronic kidney disease by targeting CNR1–ERK/ELK-1 signaling	3
Systemic and tissue-specific spexin response to acute treadmill exercise in rats	3
Correlation between serum angiotensin-converting enzyme (ACE) levels and intervertebral disc degeneration	3
Plasma angiotensinogen is associated with higher 24-hour ambulatory blood pressure independently of plasma angiotensin II in obese men	3
The role of orexin neuron activity in sleep/wakefulness regulation	3
Angiotensin-(1−7) mediated calcium signalling by MAS	3
Downregulation of natriuretic peptide receptor-C in vascular smooth muscle cells from spontaneously hypertensive rats contributes to vascular remodeling	3
Involvement of complement peptides C3a and C5a in osteoarthritis pathology	3
The Viktor Mutt Award Lecture 2022 – Homage to an outstanding scientist	3
Cholecystokinin regulates atrial natriuretic peptide secretion through activation of NOX4–Sirt1–LEF1 signaling in beating rat hypoxic atria	3
Arginine vasopressin: Critical regulator of circadian homeostasis	3
Neurokinin B is a potential target for treating disruption of intestinal mucosal barrier in acute mechanical intestinal obstruction	3
Incretin hormones, obesity and gut microbiota	3
Internal and external modulation factors of the orexin system (REVIEW)	3
Peripheral CRF-R1/CRF-R2 antagonist, astressin C, induces a long-lasting blockade of acute stress-related visceral pain in male and female rats	3
Peptide therapeutics: current status and future opportunity with focus on nose-to-brain delivery☆	3
The actions of C-peptide in HEK293 cells are dependent upon insulin and extracellular glucose concentrations	3