Peptides

Article	Citations
In silico design of antiviral peptides targeting the spike protein of SARS-CoV-2	86
Chemical modifications to increase the therapeutic potential of antimicrobial peptides	72
Nisin—A lantibiotic with immunomodulatory properties: A review	51
Immunomodulatory peptides—A promising source for novel functional food production and drug discovery	45
Intestinal glucagon-like peptide-1 effects on food intake: Physiological relevance and emerging mechanisms	44
The critical role of CCK in the regulation of food intake and diet-induced obesity	37
An update on peptide-based therapies for type 2 diabetes and obesity	37
Antiviral peptides against Coronaviridae family: A review	35
GLP-1 and GIP receptor signaling in beta cells – A review of receptor interactions and co-stimulation	34
Amylin brain circuitry	33
Soybean proteins/peptides: A review on their importance, biosynthesis, vacuolar sorting, and accumulation in seeds	32
Glycopeptide drugs: A pharmacological dimension between “Small Molecules” and “Biologics”	32
An overview of the insulin signaling pathway in model organisms Drosophila melanogaster and Caenorhabditis elegans	29
NUCB2/nesfatin-1 – Inhibitory effects on food intake, body weight and metabolism	28
Peptides to combat viral infectious diseases	27
Strategies for improving stability and pharmacokinetic characteristics of radiolabeled peptides for imaging and therapy	26
Antimicrobial peptides in domestic animals and their applications in veterinary medicine	26
Extra-oral bitter taste receptors: New targets against obesity?	25
Adrenomedullin – Current perspective on a peptide hormone with significant therapeutic potential	25
Glucagon-based therapy: Past, present and future	23
Effects of microbiome changes on endocrine ghrelin signaling – A systematic review	23
Melanin-concentrating hormone and food intake control: Sites of action, peptide interactions, and appetition	21
Arginine vasopressin: Direct and indirect action on metabolism	21
The role of kallikrein-kinin and renin-angiotensin systems in COVID-19 infection	21
Peptides in the regulation of glucagon secretion	20

An insight into biological activities of native cyclotides for potential applications in agriculture and pharmaceutics	20
PACAP orchestration of stress-related responses in neural circuits	20
Circulating products of C-type natriuretic peptide and links with organ function in health and disease	20
Angiotensin-converting enzyme 2 (ACE2): Two decades of revelations and re-evaluation	20
Vasopressin and copeptin release during sepsis and septic shock	19
Orexin (hypocretin) participates in central autonomic regulation during fight-or-flight response	19
Endogenous Opiates and Behavior: 2018	19
Demystifying functional role of cocaine- and amphetamine-related transcript (CART) peptide in control of energy homeostasis: A twenty-five year expedition	18
Apelin pathway in cardiovascular, kidney, and metabolic diseases: Therapeutic role of apelin analogs and apelin receptor agonists	18
Whether short peptides are good candidates for future neuroprotective therapeutics?	17
Do orexin/hypocretin neurons signal stress or reward?	17
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity	17
Modulation of cathelicidin and defensins by histone deacetylase inhibitors: A potential treatment for multi-drug resistant infectious diseases	16
Antimicrobial-wound healing peptides: Dual-function molecules for the treatment of skin injuries	16
Liraglutide ameliorates lipotoxicity-induced inflammation through the mTORC1 signalling pathway	16
The role of diverse LURE-type cysteine-rich peptides as signaling molecules in plant reproduction	16
Plant-derived peptides improving lipid and glucose metabolism	15
Glucagon receptor antagonism promotes the production of gut proglucagon-derived peptides in diabetic mice	15
Antiviral peptides against Enterovirus A71 causing hand, foot and mouth disease	15
Appetite regulation by plant-derived bioactive peptides for promoting health	14
Biotechnological applications of versatile plant lipid transfer proteins (LTPs)	14
Hemoglobin-derived peptides and mood regulation	14
Dulaglutide, a long-acting GLP-1 receptor agonist, can improve hyperandrogenemia and ovarian function in DHEA-induced PCOS rats	14
Potential of plant-derived peptides for the improvement of memory and cognitive function	14
Hypotensive peptides derived from plant proteins	14
Chemerin/CMKLR1 ameliorates nonalcoholic steatohepatitis by promoting autophagy and alleviating oxidative stress through the JAK2-STAT3 pathway	14
Involvement of complement peptides C3a and C5a in osteoarthritis pathology	13
Endogenous opiates and behavior: 2019	13
LP2, the first lanthipeptide GPCR agonist in a human pharmacokinetics and safety study	13
The brain oxytocin and corticotropin-releasing factor systems in grieving mothers: What we know and what we need to learn	13
Applications of amphipathic and cationic cyclic cell-penetrating peptides: Significant therapeutic delivery tool	12
Interactions between nesfatin-1 and the autonomic nervous system—An overview	12
The search for opioid analgesics with limited tolerance liability	12
NDP-MSH treatment recovers marginal lungs during ex vivo lung perfusion (EVLP)	12
Ghrelin mitigates MPP+-induced cytotoxicity: Involvement of ERK1/2-mediated Nrf2/HO-1 and endoplasmic reticulum stress PERK signaling pathway	12
Orexin receptors in the CA1 region of hippocampus modulate the stress-induced antinociceptive responses in an animal model of persistent inflammatory pain	11
Endogenous opiates and behavior: 2020	11
Evaluation of VGF peptides as potential anti-obesity candidates in pre-clinical animal models	11
CLAVATA3, a plant peptide controlling stem cell fate in the meristem	11
CCHamide2-receptor regulates feeding behavior in the pea aphid, Acyrthosiphon pisum	11
Angiotensin-(1−7), a protective peptide against vascular aging	11
Circulating microRNAs associated with C-type natriuretic peptide in childhood obesity	11
Angiotensin-(1-7) protects against sepsis-associated left ventricular dysfunction induced by lipopolysaccharide	11
B1CTcu5: A frog-derived brevinin-1 peptide with anti-tuberculosis activity	11
Identification and in vivo validation of a 9-mer peptide derived from FSHβ with FSHR antagonist activity	10
An angiotensin-converting enzyme-2-derived heptapeptide GK-7 for SARS-CoV-2 spike blockade	10
Dipeptidyl peptidase-4 and GLP-1 interplay in STC-1 and GLUTag cell lines	10
Natriuretic peptides and neprilysin inhibition in hypertension and hypertensive organ damage	10
Alamandine, a derivative of angiotensin-(1-7), alleviates sepsis-associated renal inflammation and apoptosis by inhibiting the PI3K/Ak and MAPK pathways	10
The molecular pharmacology of glucagon agonists in diabetes and obesity	10

NMR three-dimensional structure of the cationic peptide Stigmurin from Tityus stigmurus scorpion venom: In vitro antioxidant and in vivo antibacterial and healing activity	10
Sublancin protects against methicillin-resistant Staphylococcus aureus infection by the combined modulation of innate immune response and microbiota	10
Deletion of growth hormone receptor in hypothalamic neurons affects the adaptation capacity to aerobic exercise	10
Gap junction coupling and islet delta-cell function in health and disease	10
Ghrelin ameliorates cardiac fibrosis after myocardial infarction by regulating the Nrf2/NADPH/ROS pathway	10
Host defense peptides as immunomodulators: The other side of the coin	10
Acute social defeat stress upregulates gonadotrophin inhibitory hormone and its receptor but not corticotropin-releasing hormone and ACTH in the Male Nile Tilapia (Oreochromis niloticus)	10
Molecular mechanisms of plant peptide binding to receptors	9
The truncated human beta-defensin 118 can modulate lipopolysaccharide mediated inflammatory response in RAW264.7 macrophages	9
Pancreatic polypeptide revisited: Potential therapeutic effects in obesity-diabetes	9
LVV-hemorphin-7 (LVV-H7) plays a role in antinociception in a rat model of alcohol-induced pain disorders	9
Prolactin neuroprotective action against excitotoxic insult in the hippocampus of male mice	9
Postnatal AVP treatments prevent social deficit in adolescence of valproic acid-induced rat autism model	9
Antifungal activity of peptide MSI-1 against Cryptococcus neoformans infection in vitro and in murine cryptococcal meningoencephalitis	9
Cathelicidin-NV from Nanorana ventripunctata effectively protects HaCaT cells, ameliorating ultraviolet B-induced skin photoaging	9
Antimalarial effect of cell penetrating peptides derived from the junctional region of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase	9
LL-37-induced caspase-independent apoptosis is associated with plasma membrane permeabilization in human osteoblast-like cells	9
Neuronal calcitonin gene-related peptide promotes prostate tumor growth in the bone microenvironment	9
Effect of diet-induced obesity on kisspeptin-neurokinin B-dynorphin A neurons in the arcuate nucleus and luteinizing hormone secretion in sex hormone-primed male and female rats	9
Oral oxytocin delivery with proton pump inhibitor pretreatment decreases food intake	9
Effect of Fc-Elabela-21 on renal ischemia/reperfusion injury in mice: Mediation of anti-apoptotic effect via Akt phosphorylation	9
Effects and signaling pathways of Elabela in the cardiovascular system	9
What can we learn about functional importance of human antimicrobial peptide LL-37 in the oral environment from severe congenital neutropenia (Kostmann disease)?	9
Irisin lowers blood pressure in Zucker diabetic rats by regulating the functions of renal angiotensin II type 1 receptor via the inhibition of the NF-κB signaling pathway	9
Diminazene Aceturate, an angiotensin converting enzyme 2 (ACE2) activator, promotes cardioprotection in ischemia/reperfusion-induced cardiac injury	9
The involvement of orexin 1 and cannabinoid 1 receptors within the ventrolateral periaqueductal gray matter in the modulation of migraine-induced anxiety and social behavior deficits of rats	9
Cardio-protective effects of angiotensin-(1-5) via mas receptor in rats against ischemic-perfusion injury	9
Role of orexin receptors within the dentate gyrus in antinociception induced by chemical stimulation of the lateral hypothalamus in an animal model of inflammatory pain	9
Review of antiviral peptides for use against zoonotic and selected non-zoonotic viruses	9
Neuromodulatory peptides: Orally active anxiolytic-like and antidepressant-like peptides derived from dietary plant proteins	8
Apelin improves cardiac function mainly through peripheral vasodilation in a mouse model of dilated cardiomyopathy	8
The impact of inflammatory stress on hypothalamic kisspeptin neurons: Mechanisms underlying inflammation-associated infertility in humans and domestic animals	8
Peptidomics of enteroendocrine cells and characterisation of potential effects of a novel preprogastrin derived-peptide on glucose tolerance in lean mice	8
Nociceptin/orphanin FQ receptor system blockade as an innovative strategy for increasing resilience to stress	8
Effect of intracerebroventricular administration of two molecular forms of sulfated CCK octapeptide on anxiety-like behavior in the zebrafish danio rerio	8
ACE2 suppresses the inflammatory response in LPS-induced porcine intestinal epithelial cells via regulating the NF-κB and MAPK pathways	8
Urocortin3: Local inducer of somatostatin release and bellwether of beta cell maturity	8
Root meristem growth factor RGF, a sulfated peptide hormone in plants	8
Immunoneutralization of human angiotensin-(1-12) with a monoclonal antibody in a humanized model of hypertension	8
Characterization of four urotensin II receptors (UTS2Rs) in chickens	8
Associations of serum kisspeptin levels with metabolic and reproductive parameters in men	8
Structure and function of cationic hylin bioactive peptides from the tree frog Boana pulchella in interaction with lipid membranes	8
Antimicrobial peptide selection from Lippia spp leaf transcriptomes	8
Roles of gastrointestinal polypeptides in intestinal barrier regulation	8
Physiological functions and potential clinical applications of motilin	8
A synthetic peptide AWRK6 ameliorates metabolic associated fatty liver disease: involvement of lipid and glucose homeostasis	8
Antiosteoporosis effects of a marine antimicrobial peptide pardaxin via regulation of the osteogenesis pathway	8
The renin-angiotensin system and cardiovascular autonomic control in aging	8
Reptilian β-defensins: Expanding the repertoire of known crocodylian peptides	8
Neuropeptide Y gene variants in obesity, dietary intake, blood pressure, lipid and glucose metabolism: A longitudinal birth cohort study	8
Physiological role of K+ channels in irisin-induced vasodilation in rat thoracic aorta	8
Exploring the role of glycoprotein hormone GPA2/GPB5 in the medically important insect, Rhodnius prolixus	7
Plasma levels of apelin are reduced in patients with liver fibrosis and cirrhosis but are not correlated with circulating levels of bone morphogenetic protein 9 and 10	7
Mendelian randomization study of the relation between adiponectin and heart function, unravelling the paradox	7
Neandertal introgression and accumulation of hypomorphic mutations in the neuropeptide S (NPS) system promote attenuated functionality	7
Novel humanin analogs confer neuroprotection and myoprotection to neuronal and myoblast cell cultures exposed to ischemia-like and doxorubicin-induced cell death insults	7
The cyclopeptide <alpha>-amatoxin induced hepatic injury via the mitochondrial apoptotic pathway associated with oxidative stress	7
Identification of cells expressing Calcitonins A and B, PDF and ACP in Locusta migratoria using cross-reacting antisera and in situ hybridization	7
Estrogen and gut satiety hormones in vagus-hindbrain axis	7
Pituitary adenylate cyclase-activating polypeptide: Protective effects in stroke and dementia	7
Synthetic peptide SVVYGLR upregulates cell motility and facilitates oral mucosal wound healing	7
Beneficial effects of galanin system on diabetic peripheral neuropathic pain and its complications	7
Oxytocin ameliorates KCC2 decrease induced by oral bacteria-derived LPS that affect rat primary cultured cells and PC-12 cells	7
Detection of neuropeptides in vivo and open questions for current and upcoming fluorescent sensors for neuropeptides	7
Albumin binding Nanofitins, a new scaffold to extend half-life of biologics – a case study with exenatide peptide	7
Semaglutide early intervention attenuated testicular dysfunction by targeting the GLP-1–PPAR-α–Kisspeptin–Steroidogenesis signaling pathway in a testicular ischemia-reperfusion rat model	7
Ghrelin inhibited pressure overload–induced cardiac hypertrophy by promoting autophagy via CaMKK/AMPK signaling pathway	7
Hypothalamic kisspeptin neurons as potential mediators of estradiol negative and positive feedback	7
Structural and functional characterization of NDBP-4 family antimicrobial peptides from the scorpion Mesomexovis variegatus	7
[MeArg1, NLe10]-apelin-12: Optimization of solid-phase synthesis and evaluation of biological properties in vitro and in vivo	7
Pharmaceutical grade synthetic peptide Thr-Glu-Lys-Lys-Arg-Arg-Glu-Thr-Val-Glu-Arg-Glu-Lys-Glu ameliorates DSS-induced murine colitis by reducing the number and pro-inflammatory activity of colon tiss	7
Synthesis of potent antagonists of receptors for growth hormone-releasing hormone with antitumor and anti-inflammatory activity	7
Involvement of histone deacetylase 1/2 in adrenocorticotropic hormone synthesis and proliferation of corticotroph tumor AtT-20 cells	7
The neuropeptide SMYamide, a SIFamide paralog, is expressed by salivary gland innervating neurons in the American cockroach and likely functions as a hormone	7
The mediation by GLP-1 receptors of glucagon-induced insulin secretion revisited in GLP-1 receptor knockout mice	7
The effect of acute exercise on pre-prandial ghrelin levels in healthy adults: A systematic review and meta-analysis	7
Identification of a crocodylian β-defensin variant from Alligator mississippiensis with antimicrobial and antibiofilm activity	7
Blood and aqueous humor phoenixin, endocan and spexin in patients with diabetes mellitus and cataract with and without diabetic retinopathy	7
The SNX-482 peptide from Hysterocrates gigas spider acts as an immunomodulatory molecule activating macrophages	7
Dual-agonist incretin peptides from fish with potential for obesity-related Type 2 diabetes therapy – A review	7

Antimicrobial peptide production in response to gut microbiota imbalance	7
Parkinson disease: Protective role and function of neuropeptides	7
Opioid Peptides and Their Receptors in Chickens: Structure, Functionality, and Tissue Distribution	7
Modulatory role of PACAP and VIP on HIFs expression in lung adenocarcinoma	7
Apelin inhibits an endothelium-derived hyperpolarizing factor-like pathway in rat cerebral arteries	7
Glucagon-like peptide-1 receptor promotes osteoblast differentiation of dental pulp stem cells and bone formation in a zebrafish scale regeneration model	7
Chromogranin A (CGA)-derived polypeptide (CGA47–66) inhibits TNF-α-induced vascular endothelial hyper-permeability through SOC-related Ca2+ signaling	7
Markers of the sympathetic, parasympathetic and sensory nervous system are altered in the human diabetic choroid	7
Impact of angiotensin II type 1 and G-protein-coupled Mas receptor expression on the pulmonary performance of patients with idiopathic pulmonary fibrosis	7