Neurochemistry International

Article	Citations
Insulin signaling pathway and related molecules: Role in neurodegeneration and Alzheimer's disease	124
A1/A2 astrocytes in central nervous system injuries and diseases: Angels or devils?	92
The effects of manganese overexposure on brain health	66
The role of air pollution in cognitive impairment and decline	62
Central nervous system delivery of molecules across the blood-brain barrier	54
Vitamin D exerts neuroprotection via SIRT1/nrf-2/ NF-kB signaling pathways against D-galactose-induced memory impairment in adult mice	54
Neuroinflammation: An overview of neurodegenerative and metabolic diseases and of biotechnological studies	53
Targeting PI3K-AKT/mTOR signaling in the prevention of autism	53
Role of microgliosis, oxidative stress and associated neuroinflammation in the pathogenesis of Parkinson's disease: The therapeutic role of Nrf2 activators	45
Neuroendocrine, neuroinflammatory and pathological outcomes of chronic stress: A story of microglial remodeling	43
Supplementation with γ-glutamylcysteine (γ-GC) lessens oxidative stress, brain inflammation and amyloid pathology and improves spatial memory in a murine model of AD	42
Ion channels and transporters in microglial function in physiology and brain diseases	40
Biomaterials in treatment of Alzheimer's disease	40
Impairment of mitochondrial function by particulate matter: Implications for the brain	39
Materials for peripheral nerve repair constructs: Natural proteins or synthetic polymers?	39
Microglia dynamics in sleep/wake states and in response to sleep loss	38
Kaemperfol alleviates pyroptosis and microglia-mediated neuroinflammation in Parkinson's disease via inhibiting p38MAPK/NF-κB signaling pathway	37
Minutes of PPAR-γ agonism and neuroprotection	37
Novel aspects of glutamine synthetase in ammonia homeostasis	36
Norepinephrine, neurodevelopment and behavior	35
Metformin attenuates rotenone-induced oxidative stress and mitochondrial damage via the AKT/Nrf2 pathway	34
ER stress associated TXNIP-NLRP3 inflammasome activation in hippocampus of human Alzheimer's disease	34
Hesperidin alleviates chronic restraint stress and lipopolysaccharide-induced Hippocampus and Frontal cortex damage in mice: Role of TLR4/NF-κB, p38 MAPK/JNK, Nrf2/ARE signaling	34
Hippocampal inflammation and oxidative stress following exposure to diesel exhaust nanoparticles in male and female mice	32
Whole body vibration training improves depression-like behaviors in a rat chronic restraint stress model	32

Antioxidant, anti-inflammatory and neuroprotective actions of resveratrol after experimental nervous system insults. Special focus on the molecular mechanisms involved	32
3D biomaterial models of human brain disease	31
Dimethyl fumarate abridged tauo-/amyloidopathy in a D-Galactose/ovariectomy-induced Alzheimer's-like disease: Modulation of AMPK/SIRT-1, AKT/CREB/BDNF, AKT/GSK-3β, adiponectin/Adipo1R, and NF-κB/IL-1β	31
Promising potential of boron compounds against Glioblastoma: In Vitro antioxidant, anti-inflammatory and anticancer studies	31
Memantine treatment exerts an antidepressant-like effect by preventing hippocampal mitochondrial dysfunction and memory impairment via upregulation of CREB/BDNF signaling in the rat model of chronic u	31
Lipid peroxidation in brain tumors	31
Endoplasmic reticulum stress and oxidative stress contribute to neuronal pyroptosis caused by cerebral venous sinus thrombosis in rats: Involvement of TXNIP/peroxynitrite-NLRP3 inflammasome activation	30
Synaptic elimination by microglia and disturbed higher brain functions	29
Secreted gingipains from Porphyromonas gingivalis increase permeability in human cerebral microvascular endothelial cells through intracellular degradation of tight junction proteins	29
Microglial circadian clock regulation of microglial structural complexity, dendritic spine density and inflammatory response	28
Noncoding RNA crosstalk in brain health and diseases	28
mTOR signaling as a molecular target for the alleviation of Alzheimer's disease pathogenesis	27
Classical HDACs in the regulation of neuroinflammation	27
How the brain fights fatty acids’ toxicity	26
Biomaterials and strategies for repairing spinal cord lesions	26
Withametelin, a novel phytosterol, alleviates neurological symptoms in EAE mouse model of multiple sclerosis via modulation of Nrf2/HO-1 and TLR4/NF-κB signaling	25
Sevoflurane anesthesia during pregnancy in mice induces cognitive impairment in the offspring by causing iron deficiency and inhibiting myelinogenesis	25
The lncRNA Ftx/miR-382-5p/Nrg1 axis improves the inflammation response of microglia and spinal cord injury repair	25
A roadmap for potassium buffering/dispersion via the glial network of the CNS	25
Importance of oxidative stress in the pathogenesis, diagnosis, and monitoring of patients with neuropsychiatric disorders, a review	25
Lycopene - A pleiotropic neuroprotective nutraceutical: Deciphering its therapeutic potentials in broad spectrum neurological disorders	25
Activated microglia-derived macrophage-like cells exacerbate brain edema after ischemic stroke correlate with astrocytic expression of aquaporin-4 and interleukin-1 alpha release	25
Adenosine kinase: An epigenetic modulator in development and disease	25
Attenuation of nociceptive and paclitaxel-induced neuropathic pain by targeting inflammatory, CGRP and substance P signaling using 3-Hydroxyflavone	24
Cryogel biomaterials for neuroscience applications	24
The principal molecular mechanisms behind the activation of Keap1/Nrf2/ARE pathway leading to neuroprotective action in Parkinson's disease	23
Restoration and targeting of aberrant neurotransmitters in Parkinson's disease therapeutics	23
Oxidative stress, inflammation and hormesis: The role of dietary and lifestyle modifications on aging	23
Involvement of microglia in disturbed fear memory regulation: Possible microglial contribution to the pathophysiology of posttraumatic stress disorder	23
Intranasal delivery of exosomes from human adipose derived stem cells at forty-eight hours post injury reduces motor and cognitive impairments following traumatic brain injury	23
Glial smog: Interplay between air pollution and astrocyte-microglia interactions	23
Cellular and molecular influencers of neuroinflammation in Alzheimer's disease: Recent concepts & roles	23
Therapeutic potential of mangiferin in the treatment of various neuropsychiatric and neurodegenerative disorders	22
Rescuing mitochondria in traumatic brain injury and intracerebral hemorrhages - A potential therapeutic approach	22
Antioxidant therapies in traumatic brain injury	22
Nanogold induces anti-inflammation against oxidative stress induced in human neural stem cells exposed to amyloid-beta peptide	22
Pharmacological relevance of CDK inhibitors in Alzheimer's disease	22
The role of Tumour Necrosis Factor in neuroinflammation associated with Parkinson's disease and targeted therapies	22
Potential of extracellular vesicles in the Parkinson's disease – Pathological mediators and biomarkers	22
Maternal high-fat diet stimulates proinflammatory pathway and increases the expression of Tryptophan Hydroxylase 2 (TPH2) and brain-derived neurotrophic factor (BDNF) in adolescent mice hippocampus	21
Potential neurotoxic activity of diverse molecules released by microglia	21
Remote ischemic conditioning reduced cerebral ischemic injury by modulating inflammatory responses and ERK activity in type 2 diabetic mice	21
Environmental toxins and Alzheimer's disease progression	21
Activated microglia facilitate the transmission of α-synuclein in Parkinson's disease	21
Orexin and Parkinson's disease: A protective neuropeptide with therapeutic potential	21
Nutraceutical based SIRT3 activators as therapeutic targets in Alzheimer's disease	21
Neuroprotective effects of curcumin via autophagy induction in 6-hydroxydopamine Parkinson's models	21
GABA-enriched teas as neuro-nutraceuticals	21
Impacts of oxidants and antioxidants on the emergence and progression of Alzheimer's disease	21
Tetradecyl 2,3-dihydroxybenzoate alleviates oligodendrocyte damage following chronic cerebral hypoperfusion through IGF-1 receptor	21

The role and therapeutic potential of exosomes in ischemic stroke	21
Cannabinoid-profiled agents improve cell survival via reduction of oxidative stress and inflammation, and Nrf2 activation in a toxic model combining hyperglycemia+Aβ1-42 peptide in rat hippocampal neu	21
Harnessing the mitochondrial integrity for neuroprotection: Therapeutic role of piperine against experimental ischemic stroke	21
Mitophagy in Huntington's disease	21
Glutamate homeostasis and dopamine signaling: Implications for psychostimulant addiction behavior	21
Brain injury and repair after intracerebral hemorrhage: The role of microglia and brain-infiltrating macrophages	21
Neurobehavioral changes arising from early life dopamine signaling perturbations	21
Fatty acids and beyond: Age and Alzheimer's disease related changes in lipids reveal the neuro-nutraceutical potential of lipids in cognition	21
A selective D2 dopamine receptor agonist alleviates depression through up-regulation of tyrosine hydroxylase and increased neurogenesis in hippocampus of the prenatally stressed rats	21
Hyperoside suppresses NLRP3 inflammasome in Parkinson's disease via Pituitary Adenylate Cyclase-Activating Polypeptide	20
Peripheral and cerebral abnormalities of the tryptophan metabolism in the depression-like rats induced by chronic unpredicted mild stress	20
Are extracellular vesicles new hope in clinical drug delivery for neurological disorders?	20
Potential roles of natural products in the targeting of proteinopathic neurodegenerative diseases	20
Abrogation of LRRK2 dependent Rab10 phosphorylation with TLR4 activation and alterations in evoked cytokine release in immune cells	20
Leptin mediates protection of hydrogen sulfide against 6-hydroxydopamine-induced Parkinson's disease: Involving enhancement in Warburg effect	20
Voluntary wheel running is capable of improving cognitive function only in the young but not the middle-aged male APPSwe/PS1De9 mice	20
Aggregation and structure of amyloid β-protein	20
The effect of aged microglia on synaptic impairment and its relevance in neurodegenerative diseases	20
CORM-3 ameliorates neurodegeneration in the amygdala and improves depression- and anxiety-like behavior in a rat model of combined traumatic brain injury and hemorrhagic shock	20
The potential impact of bushfire smoke on brain health	20
Long non-coding RNA H19: Physiological functions and involvements in central nervous system disorders	20
Ketamine for post-traumatic stress disorders and it's possible therapeutic mechanism	20
The potential of biomaterials for central nervous system cellular repair	20
Sulforaphane attenuates apoptosis of hippocampal neurons induced by high glucose via regulating endoplasmic reticulum	19
Electroacupuncture improves neuronal plasticity through the A2AR/cAMP/PKA signaling pathway in SNL rats	19
Pharmacological basis of the anxiolytic and antidepressant properties of Silexan®, an essential oil from the flowers of lavender	19
Impaired neuronal and astroglial metabolic activity in chronic unpredictable mild stress model of depression: Reversal of behavioral and metabolic deficit with lanicemine	19
Epigenetics of addiction	19
Secreted gingipains from Porphyromonas gingivalis induce microglia migration through endosomal signaling by protease-activated receptor 2	19
Neuroprotective role of taurine on MK-801-induced memory impairment and hyperlocomotion in zebrafish	19
Amelioration of diabetes-induced cognitive impairment by Transient Receptor Potential Vanilloid 2 (TRPV2) channel inhibitor: Behavioral and mechanistic study	18
HDAC6-mediated Hsp90 deacetylation reduces aggregation and toxicity of the protein alpha-synuclein by regulating chaperone-mediated autophagy	18
Estrogen protects neuroblastoma cell from amyloid-β 42 (Aβ42)-induced apoptosis via TXNIP/TRX axis and AMPK signaling	18
Neuro-nutraceutical potential of Asparagus racemosus: A review	18
Abrogating doxorubicin-induced chemobrain by immunomodulators IFN-beta 1a or infliximab: Insights to neuroimmune mechanistic hallmarks	18
Long-term oral administration of hyperoside ameliorates AD-related neuropathology and improves cognitive impairment in APP/PS1 transgenic mice	18
Noradrenaline as a key neurotransmitter in modulating microglial activation in stress response	18
Subthreshold doses of guanosine plus ketamine elicit antidepressant-like effect in a mouse model of depression induced by corticosterone: Role of GR/NF-κB/IDO-1 signaling	18
The emerging roles of absent in melanoma 2 (AIM2) inflammasome in central nervous system disorders	18
Empagliflozin nanoparticles attenuates type2 diabetes induced cognitive impairment via oxidative stress and inflammatory pathway in high fructose diet induced hyperglycemic mice	18
Astrocyte glutamate transporters are increased in an early sporadic model of synucleinopathy	18
Gastrodin promotes hippocampal neurogenesis via PDE9-cGMP-PKG pathway in mice following cerebral ischemia	17
Crocin ameliorates depressive-like behaviors induced by chronic restraint stress via the NAMPT-NAD+-SIRT1 pathway in mice	17
Dickkopf-related protein-1 inhibition attenuates amyloid-beta pathology associated to Alzheimer's disease	17
Non-pathological roles of microglial TREM2/DAP12: TREM2/DAP12 regulates the physiological functions of microglia from development to aging	17
Antioxidant responses related to temozolomide resistance in glioblastoma	17
Bidirectional gut-brain communication: A role for orexin-A	17
Crossing the blood-brain barrier: A review on drug delivery strategies using colloidal carrier systems	17
Interleukin-1 receptor antagonist ameliorates the pain hypersensitivity, spinal inflammation and oxidative stress induced by systemic lipopolysaccharide in neonatal rats	17
Reciprocal communication between astrocytes and endothelial cells is required for astrocytic glutamate transporter 1 (GLT-1) expression	17
Mitophagy in Parkinson's disease: From pathogenesis to treatment target	17
The signaling pathway PI3K/Akt/Nrf2/HO-1 plays a role in the mitochondrial protection promoted by astaxanthin in the SH-SY5Y cells exposed to hydrogen peroxide	17
Graphene-based hybrid materials as promising scaffolds for peripheral nerve regeneration	16
Evaluation of neurological effects of cerium dioxide nanoparticles doped with different amounts of zirconium following inhalation exposure in mouse models of Alzheimer's and vascular disease	16
Potential benefits of phytochemicals from Azadirachta indica against neurological disorders	16
Search for safer and potent natural inhibitors of Parkinson's disease	16
The regulatory and enzymatic functions of CRMPs in neuritogenesis, synaptic plasticity, and gene transcription	16
Estrogen receptors-β and serotonin mediate the antidepressant-like effect of an aqueous extract of pomegranate in ovariectomized rats	16
Stroke: Molecular mechanisms and therapies: Update on recent developments	16
Development of grape polyphenols as multi-targeting strategies for Alzheimer's disease	16
Blocking the EGFR/p38/NF-κB signaling pathway alleviates disruption of BSCB and subsequent inflammation after spinal cord injury	16
Olfactory cell cultures to investigate health effects of air pollution exposure: Implications for neurodegeneration	16
Role of nutraceuticals in cognition during aging and related disorders	16
Tinospora cordifolia ameliorates brain functions impairments associated with high fat diet induced obesity	15
Polydatin alleviates parkinsonism in MPTP-model mice by enhancing glycolysis in dopaminergic neurons	15
Effects of enriched environment on microglia and functional white matter recovery in rats with post stroke cognitive impairment	15
CORM-3 improves emotional changes induced by hemorrhagic shock via the inhibition of pyroptosis in the amygdala	15
Inhibition of mitochondrial pyruvate carrier 1 by lapatinib ditosylate mitigates Alzheimer's-like disease in D-galactose/ovariectomized rats	15
Nanocarriers for effective nutraceutical delivery to the brain	15
HAGLR aggravates neuropathic pain and promotes inflammatory response and apoptosis of lipopolysaccharide-treated SH-SY5Y cells by sequestering miR-182–5p from ATAT1 and activating NLRP3 inflammasome	15
Hypothalamic glial cells isolated by MACS reveal that microglia and astrocytes induce hypothalamic inflammation via different processes under high-fat diet conditions	15
Irisin ameliorates the postoperative depressive-like behavior by reducing the surface expression of epidermal growth factor receptor in mice	15
The P2X7 receptor in activated microglia promotes depression- and anxiety-like behaviors in lithium -pilocarpine induced epileptic rats	15
Properties of primary cilia in melanin-concentrating hormone receptor 1-bearing hippocampal neurons in vivo and in vitro	15
Oxidative stress: A target to treat Alzheimer's disease and stroke	15
Chitosan-coated rosmarinic acid nanoemulsion nasal administration protects against LPS-induced memory deficit, neuroinflammation, and oxidative stress in Wistar rats	15
Mitochondrial quality control: Epigenetic signatures and therapeutic strategies	15
Epigenetic regulation in Huntington's disease	14
Potentilla anserine L. polysaccharide inhibits cadmium-induced neurotoxicity by attenuating autophagy	14
The S1P2 receptor regulates blood-brain barrier integrity and leukocyte extravasation with implications for neurodegenerative disease	14

Disturbance of prefrontal cortical myelination in olfactory bulbectomized mice is associated with depressive-like behavior	14
Protective role of anticancer drugs in neurodegenerative disorders: A drug repurposing approach	14
Lipopolysaccharide-induced depression is associated with estrogen receptor-α/SIRT1/NF-κB signaling pathway in old female mice	14
Pramipexole attenuates neuronal injury in Parkinson's disease by targeting miR-96 to activate BNIP3-mediated mitophagy	14
Dysfunctional proteins in neuropsychiatric disorders: From neurodegeneration to autism spectrum disorders	14
Treadmill exercise restores memory and hippocampal synaptic plasticity impairments in ovalbumin-sensitized juvenile rats: Involvement of brain-derived neurotrophic factor (BDNF)	14
Water treadmill training protects the integrity of the blood-spinal cord barrier following SCI via the BDNF/TrkB-CREB signalling pathway	14
Accumbal D2R-medium spiny neurons regulate aversive behaviors through PKA-Rap1 pathway	14
Natural biomaterials in brain repair: A focus on collagen	14
Soluble epoxide hydrolase inhibitor attenuates BBB disruption and neuroinflammation after intracerebral hemorrhage in mice	14
From ayurvedic folk medicine to preclinical neurotherapeutic role of a miraculous herb, Tinospora cordifolia	14
The role of neutrophils in mediating stroke injury in the diabetic db/db mouse brain following hypoxia-ischemia	14
Diagnostic and prognostic blood biomarkers in vascular dementia: From the viewpoint of ischemic stroke	14
Highly efficient synthesis and monoamine oxidase B inhibitory profile of demethyleneberberine, columbamine and palmatine	13
Snapshot of microglial physiological functions	13
A putative role for lncRNAs in epigenetic regulation of memory	13
NEAT1 lncRNA and amyotrophic lateral sclerosis	13
Down-regulation of astrocytic sonic hedgehog by activation of endothelin ETB receptors: Involvement in traumatic brain injury-induced disruption of blood brain barrier in a mouse model	13
Stimulation of toll-like receptor 4 downregulates the expression of α7 nicotinic acetylcholine receptors via histone deacetylase in rodent microglia	13
Enolase inhibition alters metabolic hormones and inflammatory factors to promote neuroprotection in spinal cord injury	13
Biomaterials in the treatment of Parkinson's disease	13
Protective role of vitamin B6 against mitochondria damage in Drosophila models of SCA3	13