Human Immunology

Article	Citations
Nomenclature for factors of the HLA system, update July, August and September 2021	534
Astragalus-mediated stimulation on antigen-presenting cells could result in higher IL-21 production from CXCR5+ Tfh-like cells and better IL-21-mediated effector functions	46
Defining and characterizing HLA diversity	43
Neem Leaf Glycoprotein in immunoregulation of cancer	43
Increase of autophagy marker p62 in the placenta from pregnant women with preeclampsia	41
P207 Virtual crossmatch: Could all HLA-DQB1*03:01P antigens be analyzed in the same way?	37
P210 The impact of HLA-DPB1 disparity on clinical outcome post unrelated hematopoietic stem cell transplantation between 2016 and 2021 – A single center experience	34
P215 Highly sensitized HLA B46 homozygous patient that makes antibodies to Bw4 and Bw6 public epitopes	33
P221 Identifying the specificity of non-HLA antibodies in flow cytometry crossmatch positive, HLA DSA negative patient sera	32
P401 Successful removal of flow cytometry crossmatch interference by a novel rituximab biosimilar	30
P223 Increase in diversity of characteristics of novel alleles discovered after adoption of next-generation sequencing	30
P400 Extending a virtual crossmatch analysis and reporting workflow to include HLA eplet mismatch load with risk stratification for post transplant kidney clinical decision support	28
P500 Effects of donor-specific human leukocyte antigen and non-human leukocyte antigen antibodies on antibody-mediated rejection in renal transplant recipients	28
P505 Serum pretreatment and the single antigen bead assay – A closer look	28
P524 Defining novel HLA serological specificities using a large clinical data of single antigen bead assay	27
P519 Deciphering the loss of anti-angiotensin type 1 receptor reactivity in enzyme-linked immunosorbent assay post-adsorption	27
P523 IgM DSA – Can they be detected before IgG DSA	27
P612 A comparison of the LinkSeq SABR and QType 11 real-time PCR genotyping assays	24
P618 Unexpected cross-reactivity of a previously characterized HLA-A1/A36 monoclonal antibody	23
O21 Estimating rates of immunologically incompatible organ offers caused by use of antigen-level deceased donor HLA typing for allocation	22
O15 Validation of wipe testing using the AlloSeq HCT platform	22
O23 NGS HLA typing reveals low-level maternal T cell engraftment through the detection of an unexpected DRB4	21
O30 Site-directed mutagenesis of HLA-DQ molecules reveals the amino acids crucial for binding to human monoclonal HLA-specific antibody	20
O31 Use of multiplexed, digital PCR to assess cellular chimerism and HLA loss of heterozygosity following allogeneic stem cell transplantation	19
O28 Interrogating DSA IgG characteristics and effector functions in lung transplant recipients	19

O35 Detection of circulating HLA-E in cancer patients: Potential application in cancer immunotherapy	19
P110 Long-range PCR and hybrid-capture methods for high-resolution HLA typing by NGS	18
P112 Integrating the Oxford Nanopore MinION bioinformatic pipeline into an HLA laboratory information management system for high-resolution typing workflow	18
P119 Invisible ink: Some markers for copy-neutral loss-of-heterozygosity chimerism are only detectable when they disappear	18
P116 An R program for automatic quality control of single antigen bead assays via Levey-Jennings charts	18
P701 Unconventional DSA found in histological antibody mediated rejection reported negative for antibody	17
P702 Validation of Omixon NanoTYPE HLA typing using Oxford Nanopore Technologies (ONT)	17
P715 Impact of requiring HLA typing of heart transplant candidates on virtual crossmatch and DSA interpretation	16
Poster abstracts (P)	16
P713 Simple and efficient monitoring of HLA NGS amplicons with Olerup SSP®HLA wipe test	16
Poster abstracts (P)	16
O2 Donor endothelial activation by serum from mismatched recipients	15
Nomenclature for factors of the HLA system, update January, February and March 2022	14
History of clinical intestinal transplantation	14
Epitopes, paratopes, and other topes 30 years on: Understanding what we are talking about	14
Deregulated expression of autophagy genes; PIK3C3 and RAB7A in COVID-19 patients	14
FOXP3+/CD68+ ratio within the tumor microenvironment may serve as a potential prognostic factor in classical Hodgkin lymphoma	14
High fructose diet: A risk factor for immune system dysregulation	13
Dynamics of HLA and angiotensin II type 1 receptor antibodies during pregnancy	13
Graphical user interface for the haplotype frequency estimation software Hapl-o-Mat	13
Elevated Interleukin-21 expression is correlated with systemic sclerosis’ severity in Tunisian patients	13
The causal relationship between ankylosing spondylitis and the risk of ovarian cancer	13
HLA-E*01:01 allele is associated with better response to anti-HCV therapy while homozygous status for HLA-E*01:03 allele increases the resistance to anti-HCV treatments in frequently transfused thalas	13
Identification of immune characteristics between different subtypes in kidney renal clear cell carcinoma based on lysosome-related genes to assist immunotherapy	12
Pharmacological approach for the reduction of inflammatory and prothrombotic hyperactive state in COVID-19 positive patients by acting on complement cascade	12
A comprehensive review on the role of T cell subsets and CAR-T cell therapy in Aspergillus fumigatus infection	11
Alterations in gut microbiota in Rheumatoid arthritis patients with interstitial lung Disease: A Comparative study	11
miR-150 promotes progressive T cell differentiation via inhibiting FOXP1 and RC3H1	11
Integrin mutations in blistering skin diseases and related genetically engineered mouse models	11
The Role and Research Progress of ACPA in the Diagnosis and Pathological Mechanism of Rheumatoid Arthritis	11
HLA epitopes – Empirically defined as conformational amino acids sequences of the HLA antigen and are likely to be part of the binding sites of anti-HLA antibodies	11
Single-cell transcriptomics of peripheral blood mononuclear cells indicates impaired immune and inflammatory responses in alcohol-associated hepatitis	11
Cytokine Dysregulation in pulmonary Tuberculosis: The role of TNF-α/IL-10 and TNF-α/TGF-β ratios as severity indicators	11
Evolution of anti-MICA antibodies after imlifidase infusion for a high immunological risk kidney transplantation	11
Assessment of the presence of interleukin 17+ macrophages and Th17 cells in situ in lip and oral tongue cancer	11
Cell-free DNA diagnostics in transplantation utilizing next generation sequencing	11
Predictive immunogenetic markers in COVID-19	10
Tri-SNP polymorphism in the intron of HLA-DRA1 affects type 1 diabetes susceptibility in the Finnish population	10
Contribution of macrophages to fetomaternal immunological tolerance	10
The changing landscape of HLA typing: Understanding how and when HLA typing data can be used with confidence from bench to bedside	10
Endothelial colony forming cells generated from cryopreserved peripheral blood mononuclear cells	10
T cell senescence and impaired CMV-specific response are associated with infection risk in kidney transplant recipients	10
A meta-analysis of epitopes in prostate-specific antigens identifies opportunities and knowledge gaps	10
CAPG facilitates diffuse large B-cell lymphoma cell progression through PI3K/AKT signaling pathway	10
Sema-3E/PlexinD1 axis modulates dendritic cell phenotypes and functions: Current status and future implications	10
Microarray analysis of autoantibodies can identify future Systemic Lupus Erythematosus patients	10
HLA tailored immunosuppression in living related pediatric kidney transplants in a low-income country. Cost and survival benefits	9
Aging does not affect calcium response to CCL2 and LPS in human monocytes	9
How natural selection shapes genetic differentiation in the MHC region: A case study with Native Americans	9
Xenotransplantation in transition	9

Pregnancy induced TMA in severe preeclampsia results from complement-mediated thromboinflammation	9
Efficient production of soluble class II HLA-Fc fusion proteins stabilized by interchain disulfide bond	9
Determination of soluble HLA-G serum levels in patients with adenomyosis and uterine fibroids before and after surgery	9
LINC00323 mediates the role of M1 macrophage polarization in diabetic nephropathy through PI3K/AKT signaling pathway	9
Relationship between HLA sensitization and heart transplant outcome	8
Improving time management in chimerism testing: Implementing an automated patient worklist	8
Precision in post-transplant management: Revealing epitope mismatch analysis for enhanced graft survival prediction	8
Novel null allele discovered by rapid next-gen sequencing	8
Exploring the citrullination effects on the HLA-DRB1 structure and dynamics: Implications for the rheumatoid arthritis pathogenesis	8
The clinical importance of IFN-γ and human epididymis protein 4 in Egyptian patients with epithelial ovarian cancer combined with HPV infection	8
Impact of Tocilizumab treatment on the reduction of angiotensin II type 1 receptor (AT1R) antibodies	8
Harnessing the power of immunoinformatics: Characterizing the role of T-cell immunity as an integral part of vaccine development and efficacy testing regimen	8
Improvements of Omixon NanoTYPE HLA typing using Oxford Nanopore Technologies: Addressing the DQ3 drop-out issue	7
Desensitization of HLA antibodies in a pediatric heart transplant	7
Kinetic characterization of sera antibodies – A surface plasmon resonance study	7
Undetected mixed chimerism in myeloid subset enrichments by an immunomagnetic bead-based method	7
HLA tissue typing and histocompatibility in supporting the Australian uterus transplant program	7
Synergistic effect of DSA and non-HLA antibodies on T cell-mediated rejection of adult liver allografts	7
Early detection of acute graft versus host disease by assessment of the immunity related transcriptome	7
Correlation between real time PCR and NGS on deceased donor typing and its impact on the virtual crossmatch	7
Automation of multiplexed 11-Loci HLA NGS Illumina library preparation on the HLA PRO Instrument	7
New method: For evaluating deviation from Hardy-Weinberg Equilibrium in large, real world HLA datasets	7
Chimerism testing for postmortem evaluation of solid organ and transfusion associated graft-vs-host disease	7
HLA-DR/DQ molecular mismatches for risk stratification and prediction of development of de novo donor-specific antibodies in cardiac allogeneic transplantation	7
Defining functional epitopes of human leukocyte DQ antigens using a new single antigen bead panel and engineered variants	7
The reduction in immunosuppression laboratory dilemma	6
Diversity and frequency of HLA-DRB1*15:03-DRB5* haplotypes in a large cohort: The case of the absent HLA-DRB5 revisited	6
Successful third transplant for recurrent leukemia after TLI-ATG conditioning and despite EBV-associated mixed donor chimerism	6
Validation of Alloseq Tx11 – Next Generation Sequencing of 11 classical HLA loci	6
HLA-DRB1*03:05 at the antigen equivalency crossroads	6
The use of business intelligence software to promote quality and service excellence of laboratory operations	6
A buccal swab DNA extraction method for Next Generation Sequencing	6
Misbhaving cells – Deceased donor with Crohn’s disease showed complete depletion of circulating B cells	6
Strategies for resolving and reporting uncommon null alleles in deceased donors for organ allocation	6
Long-distance phasing of short NGS reads – A novel approach to HLA haplotyping	6
Simplified technique sensitive washing steps for a robust hybrid capture target enrichment NGS assay	5
Role of the HLA-G immune checkpoint molecule in pregnancy	5
Genomic collision at the LIMS-1 locus increases risk of cellular mediated allograft rejection in heart transplanted recipients	5
Validation of tag SNPs for multiple sclerosis HLA risk alleles across the 1000 genomes panel	5
Seroconversion in liver and intestine transplant patients after one, two or three doses of adenoviral vector vaccines against SARS-CoV-2. Single center experience in Argentina	5
Polymorphisms of B-lymphocyte-associated genes CD20 and FCRL5 are associated with susceptibility to autoimmune thyroid diseases	5
MICA and MICB allele frequencies in a Southwest US cohort	5
Concentration-dependent antibody specificity profiles of human leukocyte DQ antigens and predictions of functional epitopes	5
Donor specific antibodies to DQ antigens are rare in DR antigen matched kidney transplants	5
Accommodation in allogeneic and xenogeneic organ transplantation: Prevalence, impact, and implications for monitoring and for therapeutics	5
Elevated levels of peripheral Th17 cells and Th17-related cytokines in patients with periampullary adenocarcinoma	5
Association of serum level of TGF-B1 and its genetic polymorphisms (C509T and T869C) with Ischemic heart disease in Iraqi population	5
Suppressor T helper type 17 cell responses in intestinal transplant recipients with allograft rejection	5
Evolution of HLA testing for hematopoietic stem cell transplantation: Importance of the candidate’s antibody profile for donor selection	5
Virtual crossmatch (VXM) by the numbers	5
Endothelial derived extracellular vesicles express high level of HLA class II molecules under inflammatory conditions	5
Power BI for HLA	5
HLA allelic diversity in the Waorani population of Ecuador: Its significance to their ancestry and migration	5
Changes in T helper cell-related factors in patients with type 2 diabetes mellitus after empagliflozin therapy	5
Nomenclature for factors of the HLA system, update July, August and September 2024	5
HLA-E*01:01 + HLA-E*01:01 genotype confers less susceptibility to COVID-19, while HLA-E*01:03 + HLA-E*01:03 genotype is associated with more severe disease	5
Next-generation sequencing for inborn errors of immunity	4
Identification and validation of cross-reactivity of anti-Thailand orthohantavirus nucleocapsid peptides	4
KIR copy number variations in dengue-infected patients from northeastern Thailand	4
Kinetics of Torque Teno virus in heart transplant patients	4
Introducing article numbering to Human Immunology	4
Performance assessment of the One Lambda Devyser Accept cfDNA assay in lung transplantation	4
Increased frequency of CD14+HLA-DR-/low cells in type 2 diabetes patients with poor glycemic control	4
Rational design of novel peptide-based vaccine against the emerging OZ virus	4
The frequency of HLA-DQ7 in patients at risk of coeliac disease: A haplotype to be reckoned with for screening?	4
Reduction of HLA antibodies by bi-specific antibody blinatumomab	4
Ionizing radiation and toll like receptors: A systematic review article	4
Determination of unacceptable antigens by summation of anti-HLA eplet antibody strength (MFI) based on single antigen bead assays: Excellent correlation with negative cell based cross matches	4
Multi-center evaluation of 19 loci hybrid capture NGS assay on illumina instruments	4
Exhausted NK cells and cytokine storms in COVID-19: Whether NK cell therapy could be a therapeutic choice	4
Clinical features and prognostic factors in elderly patients with sepsis in the emergency intensive care unit	4
P2RX1-Negative neutrophils promote the immunosuppressive microenvironment in Non-Small cell lung cancer by Upregulating PD-L1 expression	4
IL-33 in patients with periodontitis and chronic obstructive pulmonary disease	4
Study of association between antibodies to non-HLA kidney self-antigens and progression to chronic immune injury after kidney transplantation	4
Uncovering the rarity: DR7-DR53-DQ9 haplotype in two Caucasian patients	4
To list or not to list; A case of a highly sensitized kidney after liver transplant candidate	4
Evaluation of the performance of next generation sequencing ABO probes in a solid organ transplant population	3
39-year-old postpartum G3P2 heart transplant patient with rapid antibody response	3
“Geographical distribution of risk genotypes in pediatric patients with celiac disease in Spain”	3
Anti-Vedolizumab abrogates false positive allogeneic T and B cell flow cytometry crossmatches in solid organ transplantation	3

Negative flow cytometric crossmatch in the presence of anti-A*74:01 DSA: A case study	3
Comparison of two Elisa-based Angiotensin II-type-1 receptor (AT1R) autoantibody detection assays using an antibody cross-reactivity check approach	3
Acute heart transplant rejection in the presence of weak DSA with negative flow cytometry crossmatch	3
Treatment with bi-specific antibody blinatumomab effectively reduces HLA antibodies	3
Comparative analysis of serum pretreatment strategies to remove non-specific serum interference in HLA antibody assessment	3
Association of IL10 gene SNVs rs1800896 (A>G), rs1800871 (C>T), rs1800872 (C>A) and haplotypes with COVID-19 severity and outcome in the Brazilian population	3
HLA-DQ heterodimer mismatch number is associated with de novo donor-specific antibody development in pediatric kidney transplant recipients	3
Soluble HLA-G is upregulated in serum of patients with severe COVID-19	3
Advancements in monitoring donor-derived cell-free DNA for improved kidney retransplantation outcomes	3
Computational and atomistic studies applied to the understanding of the structural and behavioral features of the immune checkpoint HLA-G molecule and gene	3
Causal role of immune cells in lung cancer subtypes: Mendelian randomization study	3
HLA typing by Next Generation Sequencing (NGS): Validation using MGI DNBSEQ-G99	3
Persistence of HLA-specific DNA on MinION flow cells	3
Differential adsorption of HLA and non-HLA antibodies following combined liver and kidney transplantation	3
Reduction of HLA antibody in pediatric heart patients after daratumumab treatment for antibody mediated rejection	3
Use of Tocilizumab in the treatment of chronic active antibody-mediated rejection in pediatric kidney transplant recipients	3
Risk of kidney graft failure (GF) associated with HLA class II amino acid mismatches (AAMM) is highest during the first year after transplant for sensitized patients	3
The risk of preexisting donor-specific IgG antibody with a negative flow crossmatch in kidney transplantation	3
Absolute quantification of dd-cfDNA using a novel NGS assay	3
Convalescent COVID-19 monocytes exhibit altered steady-state gene expression and reduced TLR2, TLR4 and RIG-I induced cytokine expression	3
Validating residues determining epitopes and its possible application in clinical histocompatibility testing	3
HLA-G 14-bp insertion/deletion polymorphism and risk of coronavirus disease 2019 (COVID-19) among Iraqi patients	3
Association of methylenetetrahydrofolate reductase (MTHFR) C677T, MTHFR A1298C, and CYP3A4 A290G gene polymorphisms with clinical outcomes of HLA-matched sibling allogeneic hematopoietic cell transpla	3
Assessing impacts of transfusions on HLA sensitization in pre-hematopoietic stem cell transplant patients	3
Population study to define HLA in Mohawk First Nation in Quebec	3
Non-coding mismatches in HLA Class I genes in the presence of DPB1 mismatches predict worse outcomes in hematopoietic cell transplantation	3
The presence of angiotensin type 1 receptor (AT1R) antibodies is associated with increased peripheral blood biomarkers and vasculopathy in cardiac transplant rejection	3
Non-permissive HLA-DPB1 mismatches are associated with increased 1-year mortality after unrelated donor hematopoietic cell transplantation for non-malignant disorders	3
Protein losing enteropathy may pose a hidden danger to prospective heart transplant patients	3
LILR full gene variation in European and African American cohorts	3
Exhaustion profile on classical monocytes after LPS stimulation on Crohn’s disease patients	3
HLA-DRB3/4/5 mismatches were unintentionally avoided in allogenic hematopoietic stem cell transplants	3
Nomenclature for factors of the HLA system, update October, November and December 2022	3
Successful transplantation across high titer pre-existing donor-specific antibodies (DSA) in addition to cases involving de novo DSA with no antibody-mediated rejection	3
HLA homozygosity is associated with Non-Hodgkin lymphoma	3
Expression and function of the major histocompatibility complex (MHC) class I chain-related A (MICA)*010 in NK cell killing activity	2
P611 A case of complex HLA typing using a buccal swab from a patient after two hematopoietic cell transplants	2
P403 The adsorption crossmatch cells and elution (AXE) technique to identify true HLA specific antibodies	2
Reduced PCR-generated errors from a hybrid capture-based NGS assay for HLA typing	2
Autobiographical perspectives on HLA epitopes: Past, present and future	2
Correlation of serum matrix metalloproteinase 3 with osteoporosis in patients of postmenopausal rheumatoid arthritis	2
USP8 targeted by Mir-874-3p promotes trophoblastic cell invasion by stabilizing the expression of ENaC on trophoblast membrane	2
P208 Scratching the surface: Pronase treatment does not reduce the expression of HLA on lymphocytes and improves the sensitivity of B cell flow cytometry crossmatch by reducing nonspecific background	2
Association of killer cell immunoglobulin-like receptor genes with primary Sjögren’s syndrome among Chinese population	2
Clinical, immunological and genomic characteristics of children with X-linked agammaglobulinemia from Kerala, South India	2
Harnessing the potential of red blood cells in immunotherapy	2
Oncolytic virotherapy in hematopoietic stem cell transplantation	2
Inflammatory bowel disease and osteoporosis: Common genetic effects, pleiotropy, and causality	2
P607 5Q deletion detected by STR testing	2
P525 Cracking the code: Exploring the connection between COVID-19 vaccines and HLA antibodies in kidney transplant candidates	2
P218 Association of HLA-DRB1*04 with acute severe hepatitis of unknown aetiology in children: Results from an Irish cohort	2
“Transplantomics” for predicting allograft rejection: real-life applications and new strategies from Network Medicine	2
MBL2 gene polymorphisms related to HIV-1 infection susceptibility and treatment response	2
False-positive reactivity of anti-human leukocyte antigen antibodies detected using the single-antigen bead assay	2
From antigens to eplets: The evolution of HLA	2
Decoding the contextual duality of CD40 functions	2
In-silico study of influence of HLA heterogeneity on CTL responses across ethnicities to SARS-CoV-2	2
Telomeres and immunodeficiencies	2
HLA-A, -B, and -DRB1 allele and haplotype frequencies of 5,000 bone marrow registry from Pará (Amazon Forest Region)	2
HLA in Las Alpujarras Mts., South-East Spain: A Renaissance process of population artificial substitution	2
P225 Daratumumab-induced interference with HLA crossmatching in cardiac amyloidosis patients awaiting heart transplantation	2
P605 Genotyping discrepancies in different tests in a relapsed stem cell recipient	2
P503 Post stem cell transplant monitoring: Next generation sequencing for the assessment of chimerism on isolated cell subsets myeloid & lymphoid	2
P608 Recipient allelic imbalance in short tandem repeats chimerism testing indicates disease relapse	2
Nomenclature for factors of the HLA system, update July, August and September 2022	2
Association between oral nutrition and inflammation after intestinal transplantation	2
Performance characteristics of chimerism testing by next generation sequencing	2
Thymic stromal lymphopoietin participates in the host response to intra-amniotic inflammation leading to preterm labor and birth	2
Allele and eight-locus haplotype frequencies in population of Belgorod region, Russia	2
Differential gene expression of immune response in COVID-19 and its relationship with progression of COVID-19	2
Identification of TRIM52 as a potential biomarker in mortality risk assessment in patients with sepsis	2
HLA molecular study of patients in a public kidney transplant program in Guatemala	2
Association of Bw4/Bw6 mismatch across class I HLA loci with renal graft outcomes in first time transplants	2