Human Immunology

Article	Citations
Next-generation sequencing technologies: An overview	297
The action of TH17 cells on blood brain barrier in multiple sclerosis and experimental autoimmune encephalomyelitis	57
Humoral immune mechanisms involved in protective and pathological immunity during COVID-19	45
Dynamic changes in monocytes subsets in COVID-19 patients	44
The immunogenetic diversity of the HLA system in Mexico correlates with underlying population genetic structure	40
Utilizing nanopore sequencing technology for the rapid and comprehensive characterization of eleven HLA loci; addressing the need for deceased donor expedited HLA typing	39
pHLA3D: Updating the database of predicted three-dimensional structures of HLA with HLA-DR, HLA-DQ and HLA-DP molecules	34
Exhausted NK cells and cytokine storms in COVID-19: Whether NK cell therapy could be a therapeutic choice	34
Pharmacological approach for the reduction of inflammatory and prothrombotic hyperactive state in COVID-19 positive patients by acting on complement cascade	31
Targeting adenosine and regulatory T cells in cancer immunotherapy	30
Review of the immune mechanisms of preeclampsia and the potential of immune modulating therapy	29
High-resolution HLA typing by long reads from the R10.3 Oxford nanopore flow cells	29
A practical guide to chimerism analysis: Review of the literature and testing practices worldwide	26
Characteristics of immune cells and cytokines in patients with coronavirus disease 2019 in Guangzhou, China	26
Antigen presentation in SARS-CoV-2 infection: the role of class I HLA and ERAP polymorphisms	25
A long road/read to rapid high-resolution HLA typing: The nanopore perspective	25
PD-1 silencing improves anti-tumor activities of human mesothelin-targeted CAR T cells	25
The pro-Inflammatory cytokines effects on mobilization, self-renewal and differentiation of hematopoietic stem cells	24
Naming HLA diversity: A review of HLA nomenclature	24
Predictive immunogenetic markers in COVID-19	22
New challenges, new opportunities: Next generation sequencing and its place in the advancement of HLA typing	22
Chemotherapy vs. Immunotherapy in combating nCOVID19: An update	20
New genetic predictors for abacavir tolerance in HLA-B*57:01 positive individuals	20
Soluble HLA-G is upregulated in serum of patients with severe COVID-19	20
HLA-DQ mismatches stimulate de novo donor specific antibodies in heart transplant recipients	20

Contribution of macrophages to fetomaternal immunological tolerance	19
A new set of reagents and related software used for NGS based classical and non-classical HLA typing showing evidence for a greater HLA haplotype diversity	18
Eplet mismatch scores and de novo donor-specific antibody development in simultaneous pancreas-kidney transplantation	18
Computational design of a novel multi-epitope vaccine against Coxiella burnetii	18
Puzzling out the COVID-19: Therapy targeting HLA-G and HLA-E	18
High-resolution HLA allele and haplotype frequencies in several unrelated populations determined by next generation sequencing: 17th International HLA and Immunogenetics Workshop joint report	18
The role of immune-mediated alterations and disorders in ALS disease	17
Challenges in the application of NGS in the clinical laboratory	17
Anti-AT1R autoantibodies and prediction of the severity of Covid-19	16
Landscapes and dynamic diversifications of B-cell receptor repertoires in COVID-19 patients	16
The acidic tumour microenvironment: Manipulating the immune response to elicit escape	15
Distribution of CD36 deficiency in different Chinese ethnic groups	15
HLA-E typing of more than 2.5 million potential hematopoietic stem cell donors: Methods and population-specific allele frequencies	15
Role of the HLA-G immune checkpoint molecule in pregnancy	15
Pregnancy induced TMA in severe preeclampsia results from complement-mediated thromboinflammation	15
The B7-H4 gene induces immune escape partly via upregulating the PD-1/Stat3 pathway in non-small cell lung cancer	14
Implementation of molecular matching in transplantation requires further characterization of both immunogenicity and antigenicity of individual HLA epitopes	14
Circulating IFN-γ producing CD4+ T cells and IL-17A producing CD4+ T cells, HLA-shared epitope and ACPA may characterize the clinical response to therapy in rheumatoid arthritis patients	14
The role of decidual regulatory T cells in the induction and maintenance of fetal antigen-specific tolerance: Imbalance between regulatory and cytotoxic T cells in pregnancy complications	14
Genome Canada precision medicine strategy for structured national implementation of epitope matching in renal transplantation	14
High fructose diet: A risk factor for immune system dysregulation	14
Clinical utility of next generation sequencing based HLA typing for disease association and pharmacogenetic testing	13
Lactic acid in alternative polarization and function of macrophages in tumor microenvironment	13
Roles and Regulation of Growth differentiation factor-15 in the Immune and tumor microenvironment	13
NGS and HLA: The long road ahead	13
HLA-DRB1*04 may predict the severity of disease in a group of Iranian COVID-19 patients	13
Genetic polymorphisms and expression of NLRP3 inflammasome-related genes are associated with Philadelphia chromosome-negative myeloproliferative neoplasms	13
COVID-19 does not impact HLA antibody profile in a series of waitlisted renal transplant candidates	13
A snapshot of human leukocyte antigen (HLA) diversity using data from the Allele Frequency Net Database	13
Expression analysis of immune-regulatory molecules HLA-G, HLA-E and IDO in endometrial cancer	13
Current donor selection strategies for allogeneic hematopoietic cell transplantation	12
The respective relevance of sensitization to alloantigens and xenoantigens in pig organ xenotransplantation	12
Molecular and immunological developments in placentas	12
Increased Indoleamine 2, 3-Dioxygenase expression modulates Th1/Th17/Th22 and Treg pathway in humans with Helicobacter Pylori-Infected gastric mucosa	12
Improving the function of neutrophils from chronic granulomatous disease patients using mesenchymal stem cells’ exosomes	12
Human leukocyte antigen class-I variation is associated with atopic dermatitis: A case-control study	12
Next-generation sequencing for inborn errors of immunity	11
Peripheral cells from patients with systemic sclerosis disease co-expressing M1 and M2 monocyte/macrophage surface markers: Relation to the degree of skin involvement	11
Development of de novo HLA donor specific antibodies (HLA-DSA), HLA antibodies (HLA-Ab) and allograft rejection post blood transfusion in kidney transplant recipients	11
Incidence and impact of allele-specific anti-HLA antibodies and high-resolution HLA genotyping on assessing immunologic compatibility	11
Association of vimentin antibody and other non-HLA antibodies with treated antibody mediated rejection in heart transplant recipients	10
Diagnosing coeliac disease: A literature review	10
In utero immune programming of autism spectrum disorder (ASD)	10
A clinician’s guide to HLA matching in allogeneic hematopoietic stem cell transplant	10
How natural selection shapes genetic differentiation in the MHC region: A case study with Native Americans	10
Current HLA testing recommendations to support HCT	10
ARHGDIB and AT1R autoantibodies are differentially related to the development and presence of chronic antibody-mediated rejection and fibrosis in kidney allografts	10
Vitamin D and risk of ankylosing spondylitis: A two-sample mendelian randomization study	10
HLA-B*15 predicts survival in Egyptian patients with COVID-19	10
HLA haplotype frequency estimation for heterogeneous populations using a graph-based imputation algorithm	10

Cytokine IP-10 and GM-CSF are prognostic biomarkers for severity in secondary dengue infection	10
Immunogenicity, effectiveness, safety and psychological impact of COVID-19 mRNA vaccines	10
The utility of second single antigen bead assay: Clearing the water or stirring up mud?	10
Genetic polymorphisms of proteasome subunit genes of the MHC-I antigen-presenting system are associated with cervical cancer in a Chinese Han population	10
Cell-free DNA diagnostics in transplantation utilizing next generation sequencing	10
The immune potential of decidua-resident CD16+CD56+ NK cells in human pregnancy	9
Tri-SNP polymorphism in the intron of HLA-DRA1 affects type 1 diabetes susceptibility in the Finnish population	9
Changes in T helper cell-related factors in patients with type 2 diabetes mellitus after empagliflozin therapy	9
Implication of IL-17 producing ɑβT and γδT cells in patients with ovarian cancer	9
High resolution allele genotyping and haplotype frequencies for NGS based HLA 11 loci of 5266 Hong Kong Chinese bone marrow donors	9
Oncolytic virotherapy in hematopoietic stem cell transplantation	9
High-resolution HLA allele and haplotype frequencies of the Saudi Arabian population based on 45,457 individuals and corresponding stem cell donor matching probabilities	9
Association of HLA class II (-DRB1,-DQB1,-DPB1) alleles and haplotypes on susceptibility to aplastic anemia in northern Chinese Han	8
Antinuclear antibodies in patients with endometriosis: A cross-sectional study in 94 patients	8
Myeloid-derived suppressor cells and regulatory T cells share common immunoregulatory pathways-related microRNAs that are dysregulated by acute lymphoblastic leukemia and chemotherapy	8
The utility of imputation for molecular mismatch analysis in solid organ transplantation	8
Applications of next-generation sequencing in hematologic malignancies	8
Hyperglycemia and dyslipidemia: Reduced HLA-DR expression in monocyte subpopulations from diabetes patients	8
Genetic diversity of HLA system in two populations from Yucatán, Mexico: Mérida and rural Yucatán	8
Reducing number of laboratories performing complement dependent cytotoxicity crossmatching: Reasons and conclusions	8
Genetic variants in the NF-κB signaling pathway (NFKB1, NFKBIA, NFKBIZ) and risk of critical outcome among COVID-19 patients	8
Evolution of HLA testing for hematopoietic stem cell transplantation: Importance of the candidate’s antibody profile for donor selection	8
Microbiome analysis, the immune response and transplantation in the era of next generation sequencing	8
The role of immune cells in pulmonary hypertension: Focusing on macrophages	8
HLA repertoire of 115 UAE nationals infected with SARS-CoV-2	8
Not all eplet mismatches are created equal – A cohort study illustrating implications to long-term graft outcomes	7
T follicular helper cell-mediated IL-21 production suppresses FOXP3 expression of T follicular regulatory-like cells in diffuse large B cell lymphoma patients	7
Molecular histocompatibility beyond Tears: The next generation version	7
Next-generation sequencing and clinical histocompatibility testing	7
LINC00323 mediates the role of M1 macrophage polarization in diabetic nephropathy through PI3K/AKT signaling pathway	7
IL32: The multifaceted and unconventional cytokine	7
Critical amino acid variants in HLA-DRB1 allotypes in the development of Graves’ disease and Hashimoto’s thyroiditis in the Japanese population	7
Designing of a bispecific antibody against SARS-CoV-2 spike glycoprotein targeting human entry receptors DPP4 and ACE2	7
T cell subpopulations and cytokine levels in hemodialysis patients	7
Human CD3+CD56+NKT-like cells express a range of complement receptors and C3 activation has negative effects on these cell activity and effector function	7
HLA-disease association and pleiotropy landscape in over 235,000 Finns	7
Frequencies and haplotype associations of non-expressed HLA alleles in ethnically diverse populations on the National Marrow Donor Program’s Be The Match Registry	7
T cell senescence and impaired CMV-specific response are associated with infection risk in kidney transplant recipients	7
MiR-155 regulates Th9 differentiation in children with methicillin-resistant Staphylococcus aureus pneumonia by targeting SIRT1	6
Impact of donor KIRs and recipient KIR/HLA class I combinations on GVHD in patients with acute leukemia after HLA-matched sibling HSCT	6
Conserved HLA binding peptides from five non-structural proteins of SARS-CoV-2—An in silico glance	6
Regulatory noncoding RNAs and the major histocompatibility complex	6
Concurrent typing of over 4000 samples by long-range PCR amplicon-based NGS and rSSO revealed the need to verify NGS typing for HLA allelic dropouts	6
Physical Crossmatching vs Virtual Crossmatching: The end of an era? or Why give up a good thing?	6
Association of VEGF-A and KDR polymorphisms with the development of schizophrenia	6
Role of BTLA/HVEM network in development of gastric cancer	6
Vitamin D decreases expression of NLRP1 and NLRP3 inflammasomes in placental explants from women with preeclampsia cultured with hydrogen peroxide	6
Reduced PCR-generated errors from a hybrid capture-based NGS assay for HLA typing	6
“Transplantomics” for predicting allograft rejection: real-life applications and new strategies from Network Medicine	5
Administration of high titer convalescent anti-SARS-CoV-2 plasma: From donor selection to monitoring recipient outcomes	5
The impact of microRNAs on myeloid-derived suppressor cells in cancer	5
Association of HLA-G 3′UTR polymorphisms and haplotypes with colorectal cancer susceptibility and prognosis	5
Distribution of HLA-A, -B, -C, -DRB1, -DQB1, -DPB1 allele frequencies in patients with COVID-19 bilateral pneumonia in Russians, living in the Chelyabinsk region (Russia)	5
Expression level of immune checkpoint inhibitory factors in preeclampsia	5
Gene expression patterns associated with tumor-infiltrating CD4+ and CD8+ T cells in invasive breast carcinomas	5
Ionizing radiation and toll like receptors: A systematic review article	5
Circulating long noncoding RNAs as novel bio-tools: Focus on autoimmune diseases	5
Interaction between functional polymorphisms in FCER1A and TLR2 and the severity of atopic dermatitis	5
HLA-DPB1 and HLA-C alleles are associated with leprosy in a Brazilian population	5
HLA B53 is associated with a poor outcome in black COVID-19 patients	5
hlaR: A rapid and reproducible tool to identify eplet mismatches between transplant donors and recipients	5
From antigens to eplets: The evolution of HLA	5
Predicting HLA-DPB1 permissive probabilities through a DPB1 prediction service towards the optimization of HCT donor selection	5
Contribution of survivin to the immune system, allergies and autoimmune diseases	5
Donor selection based on NK alloreactivity for patients with hematological malignancies	5
Review: HLA loss and detection in the setting of relapse from HLA-mismatched hematopoietic cell transplant	5
Dopamine promotes the progression of AML via activating NLRP3 inflammasome and IL-1β	5
Detection and characterization of the novel HLA-DPA1*02:66:02N allele, with a premature stop codon in exon 2	5
Challenges for the standardized reporting of NGS HLA genotyping: Surveying gaps between clinical and research laboratories	4
Genetic diversity of HLA system in two populations from Oaxaca, Mexico: Oaxaca city and rural Oaxaca	4
Nigella sativa oil inhibits proliferation and stimulates apoptosis of human lymphocytes in vitro	4
Performance characteristics of chimerism testing by next generation sequencing	4
The changing landscape of HLA typing: Understanding how and when HLA typing data can be used with confidence from bench to bedside	4
A high concentration of TGF-β correlates with opportunistic infection in liver and kidney transplantation	4
Concordance between predicted HLA type using next generation sequencing data generated for non-HLA purposes and clinical HLA type	4
Is the level of HLA eplet mismatch a risk factor for graft loss among kidney transplant recipients who have already formed de novo donor specific antibody?	4
Preclinical rationale and current pathways to support the first human clinical trials in cardiac xenotransplantation	4
Identification of novel HLA alleles discovered in 2019–2021	4
HLA-G 14-bp insertion/deletion polymorphism and risk of coronavirus disease 2019 (COVID-19) among Iraqi patients	4
Increase of autophagy marker p62 in the placenta from pregnant women with preeclampsia	4

Genetic diversity of HLA system in six populations from Mexico City Metropolitan Area, Mexico: Mexico City North, Mexico City South, Mexico City East, Mexico City West, Mexico City Center and rural Me	4
Allelic and haplotypic HLA diversity in indigenous Malaysian populations explored using Next Generation Sequencing	4
Distribution of HLA-A, HLA-B, HLA-C, and HLA-DRB1 alleles and haplotypes in Jingpo minority in Yunnan province of China	4
Immune and gene expression profiling during tacrolimus to everolimus conversion early after liver transplantation	4
Polymorphisms in CTLA-4 predict de novo donor specific antibody formation after kidney transplantation	4
TRBV and TRBJ usage, when paired with specific HLA alleles, associates with distinct head and neck cancer survival rates	4
False-positive reactivity of anti-human leukocyte antigen antibodies detected using the single-antigen bead assay	4
HLA antibodies are associated with deterioration of kidney allograft function irrespective of donor specificity	4
Accommodation in allogeneic and xenogeneic organ transplantation: Prevalence, impact, and implications for monitoring and for therapeutics	4
Childhood allergy susceptibility: The role of the immune system development in the in-utero period	4
Genetic diversity of HLA system in two populations from Chiapas, Mexico: Tuxtla Gutiérrez and rural Chiapas	4
Interplay of immune components and their association with recurrent pregnancy loss	4