European Journal of Medicinal Chemistry

Article	Citations
Discovery of Sortase A covalent inhibitors with benzofuranene cyanide structures as potential antibacterial agents against Staphylococcus aureus	385
Editorial Board	308
Graphical abstract TOC	163
Editorial Board	159
Photosensitizer associated with efflux pump inhibitors as a strategy for photodynamic therapy against bacterial resistance	138
Design, synthesis and biological evaluation of galantamine analogues for cognitive improvement in Alzheimer's disease	134
Identification of a selective pyruvate dehydrogenase kinase 1 (PDHK1) chemical probe by virtual screening	131
Glycoconjugates of adefovir and tenofovir as asialoglycoprotein-mediated Anti-HBV prodrugs with enhanced liver targeting	124
Discovery of new and highly effective quadruple FFA1 and PPARα/γ/δ agonists as potential anti-fatty liver agents	120
Design and preclinical evaluation of 99mTc-Labeled dimer FAPI-46 derivatives as potential tumor radiotracers	119
Structural optimization and characterization of highly potent and selective STAT3 inhibitors for the treatment of triple negative breast cancer	116
Sialyl Lewis X (sLex):Biological functions, synthetic methods and therapeutic implications	116
Design, synthesis and biological evaluation of dual CDK9/PARP inhibitors for the treatment of cancer	108
Application of deuterium in research and development of drugs	106
[18F]R91150: Improved radiosynthesis and in vivo evaluation as imaging probe for 5-HT2A receptors	102
Correction of aberrant splicing of ELP1 pre-mRNA by kinetin derivatives – A structure activity relationship study	102
Discovery of novel fluorine-containing parthenolide analogues as potential antitumor agents	95
Research progress in bifunctional small molecules for cancer immunotherapy	94
Synthetic approaches and therapeutic applications of FDA-approved antibacterial agents: A comprehensive review from 2003 to 2023	91
Structure-based discovery of novel diarylpyrimidines as potent and selective Non-Nucleoside reverse transcriptase inhibitors: From CH(CN)-Biphenyl-Diarylpyrimidines to C NNH2-Biphenyl-Diarylpyrimidine	89
Design, synthesis, and biological evaluation of novel quinoline carboxylic acid based styryl/alkyne hybrid molecule as a potent anti-adipogenic and antidyslipidemic agent via activation of Wnt/β-caten	86
Insights into NEK2 inhibitors as antitumor agents: From mechanisms to potential therapeutics	86
Discovery of highly potent dual GSPT1/BRD4 degraders with anti-AML activity	84
Discovery of novel thiazole-pleuromutilin derivatives with potent antibacterial activity	83
The assembled decoders to prepare for “bioactive X″ against progressive deterioration of liver disease: From NAFLD to HCC	83

Discovery of novel dual tubulin and MMPs inhibitors for the treatment of lung cancer and overcoming drug resistance	81
Synthesis and evaluation of piceatannol derivatives as novel arginase inhibitors with radical scavenging activity and their potential for collagen reduction in dermal fibroblasts	81
A review of kappa opioid receptor antagonists and their clinical trial landscape	81
Insights into tumor-derived exosome inhibition in cancer therapy	80
Pyrimidine-based dual-target inhibitors targeting epidermal growth factor receptor for overcoming drug resistance in cancer therapy(2006-present)	80
Recent advances in small molecule design strategies against hepatic fibrosis	79
Synthesis and biological assessment of BUB1B inhibitors for the treatment of clear cell renal cell carcinoma	79
Optimization of potent, broad-spectrum, and specific anti-influenza compounds targeting RNA polymerase PA-PB1 heterodimerization	77
Novel α-mangostin derivatives as promising antiviral agents: Isolation, synthesis, and evaluation against chikungunya virus	76
Recent research and development of inhibitors targeting sentrin-specific protease 1 for the treatment of cancers	75
Graphical abstract TOC	75
A novel series of teriflunomide derivatives as orally active inhibitors of human dihydroorotate dehydrogenase for the treatment of colorectal carcinoma	74
The polyamino-isoprenyl potentiator NV716 revives disused antibiotics against Gram-negative bacteria in broth, infected monocytes, or biofilms, by disturbing the barrier effect of their outer membrane	73
Discovery of novel Thieno[2,3-d]imidazole derivatives as agonists of human STING for antitumor immunotherapy using systemic administration	72
Corrigendum to “Design, synthesis, and evaluation of novel pleuromutilin aryl acrylate derivatives as promising broad-spectrum antibiotics especially for combatting multi-drug resistant gram-negative	72
PRMT7 in cancer: Structure, effects, and therapeutic potentials	71
Design, synthesis and biological evaluation of novel β-carbolines as antitumor agents via targeting autophagy in colorectal cancer	71
Discovery of SET domain-binding primary alkylamine-tethered degraders for the simultaneous degradation of NSD2-long and RE-IIBP isoforms	70
Clinically approved representative small-molecule drugs for cardiopathy therapy	70
Corrigendum to “Discovery of indazole inhibitors for heat shock protein 90 as anti-cancer agents” [Eur. J. Med. Chem. (2024) 116620]	69
Praeruptorin A screened by a ferrous ion probe inhibited DMT1 and ferroptosis to attenuate Doxorubicin-induced cardiomyopathy	68
Tyrosine kinase 2 inhibitors: Synthesis and applications in the treatment of autoimmune diseases	66
Circumventing Imatinib resistance in CML: Novel Telmisartan-based cell death modulators with improved activity and stability	65
Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrier	65
Quinoline heterocyclic containing plant and marine candidates against drug-resistant Mycobacterium tuberculosis: A systematic drug-ability investigation	64
Hypoxia-selective prodrug restrains tumor cells through triggering mitophagy and inducing apoptosis	64
Dual 5-HT6/SERT ligands for mitigating neuropsychiatric symptoms of dementia exerting neuroprotection against amyloid-β toxicity, memory preservation, and antidepressant-like properties	64
Regioselective pyrrolizidine bis-spirooxindoles as efficient anti-amyloidogenic agents	63
Synthesis, structure-activity relationships and molecular docking studies of phenyldiazenyl sulfonamides as aromatase inhibitors	62
Targeting phosphatases: From molecule design to clinical trials	62
EGCG-like non-competitive inhibitor of DYRK1A rescues cognitive defect in a down syndrome model	61
PROTAC unleashed: Unveiling the synthetic approaches and potential therapeutic applications	61
Synthesis and antibacterial medicinal evaluation of carbothioamido hydrazonyl thiazolylquinolone with multitargeting antimicrobial potential to combat increasingly global resistance	61
Discovery of a novel Xanthone derivative P24 for anti-AD via targeting sTGFBR3	60
Identification, in-vitro anti-plasmodial assessment and docking studies of series of tetrahydrobenzothieno[2,3-d]pyrimidine-acetamide molecular hybrids as potential antimalarial agents	59
Optimization of the C2 substituents on the 1,4-bis(arylsulfonamido)naphthalene-N,N′-diacetic acid scaffold for better inhibition of Keap1-Nrf2 protein-protein interaction	58
Synthesis and evaluation of adenosine derivatives as A1, A2A, A2B and A3 adenosine receptor ligands containing boron clusters as phenyl isosteres and selective A3 agonists	58
Discovery and optimization of 4-anilinoquinazoline derivatives spanning ATP binding site and allosteric site as effective EGFR-C797S inhibitors	57
Selective degradation of cellular BRD3 and BRD4-L promoted by PROTAC molecules in six cancer cell lines	57
Synthesis of antiplasmodial 2-aminothieno[3,2-d]pyrimidin-4(3H)-one analogues using the scaffold hopping strategy	56
Novel acridine-based LSD1 inhibitors enhance immune response in gastric cancer	55
Design, synthesis and biological evaluation of new quinazolinone-benzopyran-indole hybrid compounds promoting osteogenesis through BMP2 upregulation	55
Specific non-genetic IAP-based protein erasers (SNIPERs) as a potential therapeutic strategy	55
Synthesis and evaluation of a new class of MIF-inhibitors in activated macrophage cells and in experimental septic shock in mice	54
The untapped potential of spermidine alkaloids: Sources, structures, bioactivities and syntheses	53
Benzopyrone-mediated quinolones as potential multitargeting antibacterial agents	53
Amlexanox-modified platinum(IV) complex triggers apoptotic and autophagic bimodal death of cancer cells	52
Ultra-short lipopeptides containing d-amino acid exhibiting excellent stability and antibacterial activity against gram-positive bacteria	52
From lab to clinic: The discovery and optimization journey of PI3K inhibitors	52
Synthesis and biological evaluation of geniposide derivatives as inhibitors of hyperuricemia, inflammatory and fibrosis	52

Identification of L. infantum trypanothione synthetase inhibitors with leishmanicidal activity from a (non-biased) in-house chemical library	52
Contents continued	51
Contents continued	51
Synthetic routes and clinical application of new drugs approved by EMA during 2023	51
Discovery and optimization of 4-pyrazolyl-2-aminopyrimidine derivatives as potent spleen tyrosine kinase (SYK) inhibitors	51
Corrigendum to “Structure-based development of N-Arylindole derivatives as Pks13 inhibitors against Mycobacterium tuberculosis” [Europ. J. Med. Chem. 283 (2025) 117148]	51
Editorial Board	50
Graphical abstract TOC	50
Probing benzenesulfonamide–thiazolidinone hybrids as multitarget directed ligands for efficient control of type 2 diabetes mellitus through targeting the enzymes: α-glucosidase and carbonic anhydrase	50
Editorial Board	50
Graphical abstract TOC	49
Graphical abstract TOC	49
Editorial Board	49
Editorial Board	48
Design, synthesis, and structure-activity relationships of a novel class of quinazoline derivatives as coronavirus inhibitors	48
Graphical abstract contents continued	48
Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer	48
Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy	48
Graphical abstract TOC	47
Editorial Board	47
Contents Continued	47
Pharmacological approaches to cystic fibrosis	47
contents continued	47
Development of potent isoflavone-based formyl peptide receptor 1 (FPR1) antagonists and their effects in gastric cancer cell models	47
Discovery of tetrasubstituted thiophenes as Cisd2 activators: A potential novel therapeutic option in nonalcoholic fatty liver disease	46
Discovery and radiosensitization research of ursolic acid derivatives as SENP1 inhibitors	46
Graphical abstract TOC	46
Discovery of small-molecule protein stabilizers toward exogenous alpha-l-iduronidase to reduce the accumulated heparan sulfate in mucopolysaccharidosis type I cells	46
Straightforward access to novel mitochondriotropics derived from 2-arylethanol as potent and selective antiproliferative agents	46
Current medicinal chemistry strategies in the discovery of novel HIV-1 ribonuclease H inhibitors	46
Editorial Board	45
Graphical abstract TOC	45
A pro-death autophagy-based nanoplatform for enhancing antitumour efficacy with improved immune responses	45
Discovery of C-3 isoxazole substituted thiochromone S,S-dioxide derivatives as potent and selective inhibitors for monoamine oxidase B (MAO-B)	45
The SAR and action mechanisms of autophagy inhibitors that eliminate drug resistance	45
Editorial Board	45
Rational design, synthesis and biological evaluation of dual PARP-1/2 and TNKS1/2 inhibitors for cancer therapy	45
Contents continued	44
Editorial	44
Editorial Board	44
Editorial Board	44
Graphical abstract TOC	44
Discovery of indirubin-3′-aminooxy-acetamide derivatives as potent and selective FLT3/D835Y mutant kinase inhibitors for acute myeloid leukemia	44
Graphical abstract TOC	44
Graphical abstract TOC	44
Graphical abstract TOC	44
Graphical abstract TOC	43
Editorial Board	43
Graphical abstract TOC	43
Discovery of a potent MLL1 and WDR5 protein-protein interaction inhibitor with in vivo antitumor activity	43
Dual-target inhibitors based on ERα: Novel therapeutic approaches for endocrine resistant breast cancer	42
Discovery of ML210-Based glutathione peroxidase 4 (GPX4) degrader inducing ferroptosis of human cancer cells	42
Editorial Board	42
Halting colorectal cancer metastasis via novel dual nanomolar MMP-9/MAO-A quinoxaline-based inhibitors; design, synthesis, and evaluation	42
A decade of USFDA-approved small molecules as anti-inflammatory agents: Recent trends and Commentaries on the “industrial” perspective	42
Targeting the phosphoserine phosphatase MtSerB2 for tuberculosis drug discovery, an hybrid knowledge based /fragment based approach	42
Graphical abstract TOC	42
Antibacterial activity evaluation of pleuromutilin derivatives with 4(3H)-quinazolinone scaffold against methicillin-resistant Staphylococcus aureus	42
Pleiotropic effects of a mitochondrion-targeted glutathione reductase inhibitor on restraining tumor cells	42
The evolution paths of some reprehensive scaffolds of RORγt modulators, a perspective from medicinal chemistry	42
N-aryltetrahydroisoquinoline derivatives as HA-CD44 interaction inhibitors: Design, synthesis, computational studies, and antitumor effect	42
Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of RORγ antagonists	41
Discovery of small-molecules targeting the CCL20/CCR6 axis as first-in-class inhibitors for inflammatory bowel diseases	41
Analogues of natural products yaequinolones as potential inflammatory inhibitors: Design, synthesis and biological evaluation	41
Design, synthesis, and biological evaluation of novel 4,4′-bipyridine derivatives acting as CDK9-Cyclin T1 protein-protein interaction inhibitors against triple-negative breast cancer	40
Innate functions of natural products: A promising path for the identification of novel therapeutics	40
Targeting glycogen synthase kinase-3β for Alzheimer's disease: Recent advances and future Prospects	40
Recent advance of small-molecule drugs for clinical treatment of osteoporosis: A review	39
Targeted degradation of METTL3 against acute myeloid leukemia and gastric cancer	39
MNK, mTOR or eIF4E-selecting the best anti-tumor target for blocking translation initiation	39
Design, synthesis and promising anti-tumor efficacy of novel imidazo[1,2-a]pyridine derivatives as potent autotaxin allosteric inhibitors	39
Ferroptosis-inducing compounds synergize with docetaxel to overcome chemoresistance in docetaxel-resistant non-small cell lung cancer cells	39
Design, synthesis, and biological evaluation of novel pyrazolo [3,4-d]pyrimidine derivatives as potent PLK4 inhibitors for the treatment of TRIM37-amplified breast cancer	39
Design, synthesis, and evaluation of new anti-inflammatory natural products amide derivatives endowed with anti-blood cancer activity towards development of potential multifunctional agents against he	39
Discovery of novel pyrrolo[2,1-c][1,4]benzodiazepine-3,11-dione (PBD) derivatives as selective HDAC6 inhibitors for the efficient treatment of idiopathic pulmonary fibrosis (IPF) in vitro and in vivo	39
Design, synthesis, and anti-respiratory syncytial virus potential of novel 3-(1,2,3-triazol-1-yl)furoxazine-fused benzimidazole derivatives	39
Designing and development of phthalimides as potent anti-tubulin hybrid molecules against malaria	39
Novel 6-hydroxybenzothiazol-2-carboxamides as potent and selective monoamine oxidase B inhibitors endowed with neuroprotective activity	38
Metabolic and conformational stabilization of a VEGF-mimetic beta-hairpin peptide by click-chemistry	38
Novel benzothiazole‒urea hybrids: Design, synthesis and biological activity as potent anti-bacterial agents against MRSA	38

Optimization and SAR research at the piperazine and phenyl rings of JNJ4796 as new anti-influenza A virus agents, part 1	38
Design and evaluation of novel piperidine HIV-1 protease inhibitors with potency against DRV-resistant variants	38
Investigation of chalcogen bioisosteric replacement in a series of heterocyclic inhibitors of tryptophan 2,3-dioxygenase	38
Synthesis and anticancer activity of novel histone deacetylase inhibitors that inhibit autophagy and induce apoptosis	37
New and promising type of leukotriene B4 (LTB4) antagonists based on the 1,4-benzodioxine structure	37
Editorial Board	37
Design, synthesis, and SAR study of novel flavone 1,2,4-oxadiazole derivatives with anti-inflammatory activities for the treatment of Parkinson's disease	37
Advances on structure, bioactivity, and biosynthesis of amino acid-containing trans-AT polyketides	37
Discovery of novel ocotillol derivatives modulating glucocorticoid receptor/NF-κB signaling for the treatment of sepsis	37
Design and synthesis of aptamer-cyclometalated iridium(III) complex conjugate targeting cancer cells	37
Discovery of dual inhibitors of topoisomerase I and Cyclooxygenase-2 for colon cancer therapy	37
Similarities and differences between embryonic implantation and CTC invasion: Exploring the roles of abortifacients in cancer metastasis chemoprevention	37
Recent advances in targeting histone H3 lysine 36 methyltransferases for cancer therapy	36
Contents continued	36
Gemfibrozil derivatives as activators of soluble guanylyl cyclase – A structure-activity study	36
Graphical abstract TOC	36
Design, synthesis and antitubercular activity of novel N-(amino)piperazinyl benzothiazinones with improved safety	36
Discovery of novel TrkA allosteric inhibitors: Structure-based virtual screening, biological evaluation and preliminary SAR studies	36
Small molecules that regulate the N6-methyladenosine RNA modification as potential anti-cancer agents	36
New 4-(N-cinnamoylbutyl)aminoacridines as potential multi-stage antiplasmodial leads	36
Design, synthesis, and biological evaluation of harmine derivatives as topoisomerase I inhibitors for cancer treatment	36
Discovery of benzamide-based PI3K/HDAC dual inhibitors with marked pro-apoptosis activity in lymphoma cells	35
Identification of “dual-site”-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptase	35
Hybrid molecules based on caffeic acid as potential therapeutics: A focused review	35
Design, synthesis and biological evaluations of quinolone amides against African trypanosomiasis with improved solubility	35
Discovery of indolylacryloyl-derived oxacins as novel potential broad-spectrum antibacterial candidates	35
High throughput virtual screening (HTVS) of peptide library: Technological advancement in ligand discovery	35
Chemodynamic therapy agents Cu(II) complexes of quinoline derivatives induced ER stress and mitochondria-mediated apoptosis in SK-OV-3 cells	35
Design, synthesis, and biological evaluation of 1-styrenyl isoquinoline derivatives for anti-hepatocellular carcinoma activity and effect on mitochondria	35
A comprehensive overview of Artemisinin and its derivatives as anticancer agents	35
Novel 5-fluorouracil sensitizers for colorectal cancer therapy: Design and synthesis of S1P receptor 2 (S1PR2) antagonists	34
New aryl and acylsulfonamides as state-dependent inhibitors of Nav1.3 voltage-gated sodium channel	34
Neurotensin(8–13) analogs as dual NTS1 and NTS2 receptor ligands with enhanced effects on a mouse model of Parkinson's disease	34
Potential pharmacological strategies targeting the Niemann-Pick C1 receptor and Ebola virus glycoprotein interaction	34
Drug discovery of histone lysine demethylases (KDMs) inhibitors (progress from 2018 to present)	34
Discovery of a potent and selective inhibitor of histone lysine demethylase KDM4D	34
Discovery of the first-in-class dual PPARδ/γ partial agonist for the treatment of metabolic syndrome	34
A glycyrrhetinic acid-iridium(III) conjugate as a theranostic NIR probe for hepatocellular carcinoma with mitochondrial-targeting ability	34
Design, synthesis, and repurposing of O-aminoalkyl-sulfuretin analogs towards discovery of potential lead compounds as antileishmanial agents	34
Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy	34
Novel mono- and multivalent N-acetylneuraminic acid glycoclusters as potential broad-spectrum entry inhibitors for influenza and coronavirus infection	34
Design, synthesis and activity evaluation of isopropylsulfonyl-substituted 2,4- diarylaminopyrimidine derivatives as FAK inhibitors for the potential treatment of pancreatic cancer	34
Substituted dienes prepared from betulinic acid – Synthesis, cytotoxicity, mechanism of action, and pharmacological parameters	33
Editorial Board	33
Contents continued	33
Camptothecin structure simplification elaborated new imidazo[2,1-b]quinazoline derivative as a human topoisomerase I inhibitor with efficacy against bone cancer cells and colon adenocarcinoma	33
Graphical abstract TOC	33
Dual target PARP1/EZH2 inhibitors inducing excessive autophagy and producing synthetic lethality for triple-negative breast cancer therapy	33
Discovery of a potent, selective, and covalent ZAP-70 kinase inhibitor	32
Discovery of novel dual RAGE/SERT inhibitors for the potential treatment of the comorbidity of Alzheimer's disease and depression	32
Discovery of MDM2-p53 and MDM4-p53 protein-protein interactions small molecule dual inhibitors	32
Discovery of a potent CDKs/FLT3 PROTAC with enhanced differentiation and proliferation inhibition for AML	32
Novel C-3-(N-alkyl-aryl)-aminomethyl rifamycin SV derivatives exhibit activity against rifampicin-resistant Mycobacterium tuberculosis RpoBS522L strain and display a different binding mode at the RNAP	32
Medicinal chemistry strategies targeting NLRP3 inflammasome pathway: A recent update from 2019 to mid-2023	32
Phenotypic screening identifies a trisubstituted imidazo[1,2-a]pyridine series that induces differentiation in multiple AML cell lines	32
Drugs for the treatment of glaucoma: Targets, structure-activity relationships and clinical research	32
Antiviral drug discovery: Pyrimidine entry inhibitors for Zika and dengue viruses	32
Structure modification of anoplin for fighting resistant bacteria	32
Doxorubicin prodrug-based nanomedicines for the treatment of cancer	31
Discovery of novel 2,3-dihydro-1H-inden-1-ones as dual PDE4/AChE inhibitors with more potency against neuroinflammation for the treatment of Alzheimer's disease	31
Novel mechanistic insights – A brand new Era for anti-HBV drugs	31
Affinity-based protein profiling identifies vitamin D3 as a heat shock protein 70 antagonist that regulates hedgehog transduction in murine basal cell carcinoma	31
Natural inspired piperine-based sulfonamides and carboxylic acids as carbonic anhydrase inhibitors: Design, synthesis and biological evaluation	31
4-Hydroxy-2-pyridone derivatives with antitumor activity produced by mangrove endophytic fungus Talaromyces sp. CY-3	31
Design, synthesis, and pharmacological evaluation of indole-piperidine amides as Blood−brain barrier permeable dual cholinesterase and β-secretase inhibitors	31
Identification of novel diarylpyrimidine derivatives as potent HIV-1 non-nucleoside reverse transcriptase inhibitors against wild-type and K103N mutant viruses	31
Annual review of KRAS inhibitors in 2022	31
Optimization of peptide-based inhibitors targeting the HtrA serine protease in Chlamydia: Design, synthesis and biological evaluation of pyridone-based and N-Capping group-modified analogues	31
Seleno-vs. thioether triazine derivatives in search for new anticancer agents overcoming multidrug resistance in lymphoma	31
Inhibition of Histone Deacetylase 6 (HDAC6) as a therapeutic strategy for Alzheimer's disease: A review (2010–2020)	31
Synthesis and structure-activity relationship of new chalcone linked 5-phenyl-3-isoxazolecarboxylic acid methyl esters potentially active against drug resistant Mycobacterium tuberculosis	31
Advances in the development of phosphodiesterase-4 inhibitors	31
Novel frontiers through nitrogen substitution at 6th, 10th and 11th position of artemisinin: Synthetic approaches and antimalarial activity	31
Novel family of [RuCp(N,N)(P)]+ compounds with simultaneous anticancer and antibacterial activity: Biological evaluation and solution chemistry studies	30
Development of diphenylmethylpiperazine hybrids of chloroquinoline and triazolopyrimidine using Petasis reaction as new cysteine proteases inhibitors for malaria therapeutics	30
Novel pyridine-containing histone deacetylase inhibitors strongly arrest proliferation, induce apoptosis and modulate miRNAs in cancer cells	30
Design, synthesis and biological activity evaluation of novel scopoletin-NO donor derivatives against MCF-7 human breast cancer in vitro and in vivo	30
Discovery of seneciobipyrrolidine derivatives for the amelioration of glucose homeostasis disorders through 4E-BP1/Akt/AMPK signaling activation	30
Novel D2/5-HT receptor modulators related to cariprazine with potential implication to schizophrenia treatment	30
Discovery of PIM-1 kinase inhibitors based on the 2,5-disubstituted 1,3,4-oxadiazole scaffold against prostate cancer: Design, synthesis, in vitro and in vivo cytotoxicity investigation	30
Recent development of BTK-based dual inhibitors in the treatment of cancers	30
Synthesis and biological evaluation of 1-(4-(piperazin-1-yl)phenyl)pyridin-2(1H)-one derivatives as potential SSRIs	30
Design, synthesis, activity and molecular dynamics studies of 1,3,4-thiadiazole derivatives as selective allosteric inhibitors of SHP2 for the treatment of cancer	29
Graphical abstract TOC	29
Design, synthesis, and biological evaluation of novel highly selective non-carboxylic acid FABP1 inhibitors	29
Graphical abstract TOC	29
Recent advances in the chemistry and biology of oleanolic acid and its derivatives	29
From PROTAC to inhibitor: Structure-guided discovery of potent and orally bioavailable BET inhibitors	29
Design, synthesis of griseofamine A derivatives and development of potent antibacterial agents against MRSA	29
Graphical abstract TOC	29
Benzothiazole a privileged scaffold for Cutting-Edges anticancer agents: Exploring drug design, structure-activity relationship, and docking studies	29
Bifunctional degraders of cyclin dependent kinase 9 (CDK9): Probing the relationship between linker length, properties, and selective protein degradation	29
Discovery of 1-(phenylsulfonyl)-1H-indole-based multifunctional ligands targeting cholinesterases and 5-HT6 receptor with anti-aggregation properties against amyloid-beta and tau	29
Editorial Board	29
Modulators for palmitoylation of proteins and small molecules	29