OOIR: Observatory of International Research

Papers

(The TQCC of Immunologic Research is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Optimal chemokine receptors for enhancing immune cell trafficking in adoptive cell therapy	84
Systemic barrier dysfunction in type 2 inflammation diseases: perspective in the skin, airways, and gastrointestinal tract	56
Cytokine response following perturbation of the cervicovaginal milieu during HPV genital infection	53
A central role of stimulator of interferon genes’ adaptor protein in defensive immune response	51
Microarray profiling and functional analysis reveal the regulatory role of differentially expressed plasma circular RNAs in Hashimoto’s thyroiditis	51
The p53 status in rheumatoid arthritis with focus on fibroblast-like synoviocytes	50
TLR4 and TNFR1 blockade dampen M1 macrophage activation and shifts them towards an M2 phenotype	45
A case of atypical infantile de novo antiphospholipid syndrome presenting with neonatal ischemic stroke without any triggering risk factors as a “second hit” and review of the literature	38
Protective role of ABCC drug subfamily resistance transporters (ABCC1-7) in intestinal inflammation	35
Age-standardized incidence, prevalence, mortality rates and future projections of autoimmune diseases in China: a systematic analysis based on GBD 2021	35
α-Amanitin aggravates hepatic injury by activating oxidative stress and mitophagy via peroxiredoxin 6 inhibition	32
Blood and CSF anti-neuronal antibodies testing in psychotic syndromes: a retrospective analysis from a tertiary psychiatric hospital	31
Regulation of Tert methylation alleviates food allergy via regulating the Tert-IL10 signal pathway	30
Predictive biomarkers of response to tocilizumab in giant cell arteritis (GCA): correlations with imaging activity	25
Autophagic reprogramming of bone marrow–derived macrophages	25
Exploring CCR5 + T regulatory cell subset dysfunction in type 1 diabetes patients: implications for immune regulation	25
Quantitative evaluation of citrullinated fibrinogen for detection of neutrophil extracellular traps	24
Impact of microparticles released during murine systemic inflammation on macrophage activity and reactive nitrogen species regulation	24
MiR-7 deficiency promotes Th1 polarization of CD4+T cells and enhances the antitumor effect in adoptive cell therapy for lung cancer	22
Evolutionary preservation of CpG dinucleotides in RAG1 may elucidate the relatively high rate of methylation-mediated mutagenesis of RAG1 transposase	21
Rapid generation of an RBL cellular model to study proteins that cause allergenic reactions in vitro	21
Regnase-1 regulates inflammation in T cells of ankylosing spondylitis through the TRAF6	21
Mass cytometry revealed the circulating immune cell landscape across different Suzuki stages of Moyamoya disease	20
In silico and experimental potentials of 6-shogaol and meglumine antimoniate on Leishmania major: multiple synergistic combinations through modulation of biological properties	19
Genetic variability of three common NK and γδ T cell receptor genes (FCγ3R, NCR3, and DNAM-1) and their role in Polish patients with rheumatoid arthritis and ankylosing spondylitis	19

Artificial intelligence applications for immunology laboratory: image analysis and classification study of IIF photos	18
Targeting the neonatal Fc receptor (FcRn) is not beneficial in an animal model of chronic neuritis	17
Effect of different cytokines in combination with IL-15 on the expression of activating receptors in NK cells of patients with Behçet’s disease	16
5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivative attenuates lupus nephritis with less effect to thymocyte development	16
Correlation of plasma and urine Wnt5A with the disease activity and cutaneous lesion severity in patients with systemic lupus erythematosus	16
Immunoglobulin G4-related disease: case report and literature review	15
Hypoxia modulates human mast cell adhesion to hyaluronic acid	14
Role of booster with BNT162b2 mRNA in SARS-CoV-2 vaccination in patients with rheumatoid arthritis	14
The effect of mutatio-type on proteo-phenotype and clinico-phenotype in selected primary immunodeficiencies	14
Platelets differentially modulate CD4+ Treg activation via GPIIa/IIIb-, fibrinogen-, and PAR4-dependent pathways	13
Identification of nafamostat mesylate as a selective stimulator of NK cell IFN-γ production via metabolism-related compound library screening	13
Soluble factors from TLR4- or TCR-activated cells contribute to stability of the resting phenotype and increase the expression of CXCR4 of human memory CD4 T cells	13
Major histocompatibility complex class I molecule expression by pancreatic cancer cells is regulated by activation and inhibition of the epidermal growth factor receptor	13
A method to obtain purified free light chain monomers and dimers from urine samples of patients with multiple myeloma	13
B cell repertoire in patients with a novel BTK mutation: expanding the spectrum of atypical X-linked agammaglobulinemia	13
Hyper IgM in tricho-hepato-enteric syndrome due to TTC37 mutation	13
New-onset eosinophilic granulomatosis with polyangiitis in 2 patients during treatment with IL-5 pathway inhibitors	12
Somatic hypermutation defects in two adult hyper immunoglobulin M patients	12
ANA-specific antibodies, ANA patterns, anti-ds-DNA results, and clinical diagnosis: a laboratory and clinical audit	11
Macrophage subsets and their role: co-relation with colony-stimulating factor-1 receptor and clinical relevance	11
MiR-29a-3p negatively regulates circulating Tfh memory cells in patients with Graves’ disease by targeting ICOS	11
The influence of vitamin D supplementation on the expression of mediators of inflammation in knee osteoarthritis	11
Laboratory and clinical practices in antinuclear antibody detection and related antigens: recommendations from a Spanish multicentre survey	10
Silencing ApoC3 alleviates LPS-induced acute lung injury by inhibiting TLR signaling pathway	10
Chronic inflammatory demyelinating polyneuropathy after SARS-CoV2 vaccination: update of the literature and patient characterization	9
Chimeric antigen receptor (CAR) immunotherapy: basic principles, current advances, and future prospects in neuro-oncology	9
The effect of the BNT162b2 vaccine on antinuclear antibody and antiphospholipid antibody levels	9
Management of COVID-19 pneumonia in a child with NEMO deficiency	9
Association between SYVN1 and SEL1 genetic polymorphisms and remission in rheumatoid arthritis patients treated with TNF-α inhibitors: a machine learning approach	9
SARS-CoV-2 antibodies in inflammatory neurological conditions: a multicentre retrospective comparative study	9
Phillyrin inhibits oxidative stress and neutrophil extracellular trap formation through the KEAP1/NRF2 pathway in gouty arthritis	8
Correction to: Matrine suppresses expression of adhesion molecules and chemokines as a mechanism underlying its therapeutic effect in CNS autoimmunity	8
The influences of α-hemolytic Streptococcus on class switching and complement activation of human tonsillar cells in IgA nephropathy	8
Integrating machine learning and multi-omics analysis to develop an asparagine metabolism immunity index for improving clinical outcome and drug sensitivity in lung adenocarcinoma	8
Risk of COVID-19 and its complications in patients with atopic dermatitis undergoing dupilumab treatment—a population-based cohort study	8
Belimumab 10 years later: how drug positioning has changed	8
Gender disparities in Behçet’s syndrome: identifying distinct phenotypes through cluster analysis	8
Fructus lycii oligosaccharide alleviates acute liver injury via PI3K/Akt/mTOR pathway	7
Utility of simultaneous quantification of TREC/KREC in patients with common variable immunodeficiency phenotype: an observational study from North India	7
Inhibition of LSD1 via SP2509 attenuated the progression of rheumatoid arthritis	7
Anti-complement factor H (CFH) autoantibodies could delay pristane-induced lupus nephritis	7
Correction to: Human placental extract attenuates neurological symptoms in the experimental autoimmune encephalomyelitis model of multiple sclerosis-a putative approach in MS disease?	7
FOXP4-AS1 promotes CD8+ T cell exhaustion and esophageal cancer immune escape through USP10-stabilized PD-L1	7
Rituximab alleviates pediatric systemic lupus erythematosus associated refractory immune thrombocytopenia: a case-based review	7
Correction to: Postural orthostatic tachycardia syndrome (POTS) and other autonomic disorders after COVID-19 infection: a case series of 20 patients	7
Immunoenhancing of the anti-cancer therapy and anti-oxidative stress by co-administration of granulocyte-colony stimulating factor-mobilized stem cells or cells derived from bone marrow and/or spleen	7
Conventional Tregs in treatment-naïve rheumatoid arthritis are deficient in suppressive function with an increase in percentage of CXCR3 and CCR6 expressing Tregs	7
Deciphering autoimmune susceptibility: a meta-analysis of PTPN22 gene variants	6
Ataxia-telangiectasia in Latin America: clinical features, immunodeficiency, and mortality in a multicenter study	6
Good syndrome combined with multiple microbial pulmonary infections: case report and review of the literature	6

Association between TLR 2 (rs3804099), TLR4 (rs4986790), and TLR 9 (rs187084) polymorphism and leukemia risk: a systematic review and meta-analysis	6
Polyethylene glycol and immunology: aspects of allergic reactions and their mechanisms, as well as ways to prevent them in clinical practice	6
Low C4A copy numbers and higher HERV gene insertion contributes to increased risk of SLE, with absence of association with disease phenotype and disease activity	6
Comparative analyses of various IgE-mediated and non-IgE-mediated inducers of mast cell degranulation for in vitro study	6
The role of mitophagy-related genes in prognosis and immunotherapy of cutaneous melanoma: a comprehensive analysis based on single-cell RNA sequencing and machine learning	6
The prognostic value of IgA anti-citrullinated protein antibodies and rheumatoid factor in an early arthritis population with a treat-to-target approach	6
A comprehensive analysis of scRNA-Seq and RNA-Seq unveils B cell immune suppression in the AAV-loaded brain	6
Elevated total serum IgM predicts the presence of antiphospholipid antibodies in dysautonomia patients	6
The effects of bone marrow humoral components of B-cell acute lymphoblastic leukemia patients on natural killer cell suppression	6
Correction to: A latent pathogen infection classification system that would significantly increase healthcare safety	6
Killed whole-cell Staphylococcus aureus formulation in Montanide ISA266 and Alum adjuvants: different vaccine formulations varied in the vaccine’s potency and efficacy	5
Human antibody profiling technologies for autoimmune disease	5
IGF2BP2 promotes lung adenocarcinoma progression by regulating LOX1 and tumor-associated neutrophils	5
The intercorrelations between blood levels of ferritin, sCD163, and IL-18 in COVID-19 patients and their association to prognosis	5
Metformin suppresses gammadelta T17 cell differentiation alleviating DSS-induced colitis	5
Immune tumoral microenvironment in gliomas: focus on CD3+ T cells, Vδ1+ T cells, and microglia/macrophages	5
Circular RNA hsa_circ_0001598 promotes programmed death-ligand-1-mediated immune escape and trastuzumab resistance via sponging miR-1184 in breast cancer cells	5
PANoptosis-related genes in the prognosis and immune landscape of hepatocellular carcinoma	5
Circulating anti-hypothalamus antibodies in celiac patients: tissue transglutaminase friend or foe?	5
Dual neutralization of TGF-β and IL-21 regulates Th17/Treg balance by suppressing inflammatory signalling in the splenic lymphocytes of Staphylococcus aureus infection-induced septic arthritic mice	5
Vitamin D receptor gene polymorphisms are associated with the risk and features of myasthenia gravis in the Han Chinese population	5
Investigation of T lymphocyte subsets in children with Mycoplasma pneumoniae pneumonia	5
Cytokine storm and targeted therapy in hemophagocytic lymphohistiocytosis	5
[Cuproptosis-related immune gene signature predicts clinical benefits from anti-PD-1/PD-L1 therapy in non-small-cell lung cancer	5
ANCA detection with solid phase chemiluminescence assay: diagnostic and severity association in vasculitis	4
Functions of MAP3Ks in antiviral immunity	4
Livin promotes Th2-type immune response in airway allergic diseases	4
Flagellin conjugated Per a 10 and its T cell peptides attenuate airway inflammation and restore cellular function	4
CCR2+TREM-1+ monocytes promote natural killer T cell dysfunction contributing towards HBV disease progression	4
Prognostic value of myeloid-derived suppressor-like cells in acute myeloid leukemia: insights from immunophenotyping and clinical correlations	4
Autoimmune lymphoproliferative syndrome (ALPS) due to a novel dominant negative germline mutation in the FAS gene	4
Transcriptional upregulation of galectin-3 in multiple sclerosis	4
The association of IL-33 and systemic sclerosis: a systematic review and meta-analysis	4
Thymic tuft cells: potential “regulators” of non-mucosal tissue development and immune response	4
A ubiquitin–proteasome system-related signature to predict prognosis, immune infiltration, and therapy efficacy for breast cancer	4
Clinical relevance and frequency of cytoplasmic patterns observed in ANA-Hep-2: experience of Cairo University Hospitals	4
DAP1-2: a synthetic peptide targeting IL-1R1 receptor effectively suppresses IL-1β in vitro	4
Elastin-derived peptides (EDPs) as a potential pro-malignancy factor in human leukemia cell lines	4
Pomalidomide in patients with multiple myeloma: potential impact on the reconstitution of a functional T-cell immunity	4
5Apal, Taql, Fokl, and Bsml polymorphisms and the susceptibility of Behcet’s disease: an updated meta-analysis	4
An association study on the risk, glucocorticoids effectiveness, and prognosis of systemic lupus erythematosus: insight from mitochondrial DNA copy number	4
Induced regulatory T cells remain suppressive capability on effector T cells and synovial fibroblasts in collagen-induced arthritis	4
Optimized reagents for immunopotency assays on mesenchymal stromal cells for clinical use	4
EBV + B cell-derived exosomes promote EBV-associated T/NK-cell lymphoproliferative disease immune evasion by STAT3/IL-10/PD-L1 pathway	4
Amphotericin B for injection triggers degranulation of human LAD2 mast cells by MRGPRX2 and pseudo-allergic reactions in mice via MRGPRB2 activation	4
Hormone and reproductive factors and risk of systemic lupus erythematosus: a Mendelian randomized study	4
Patent blue V dye anaphylaxis: should basophil activation test play a role in the diagnosis?	4