OOIR: Observatory of International Research

Papers

(The TQCC of Atla-Alternatives to Laboratory Animals is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Extension of the Virtual Cell Based Assay from a 2-D to a 3-D Cell Culture Model	84
Spotlight on Three Rs Progress	36
Spotlight on Three Rs Progress	32
The Safety Assessment of Cosmetic Perfumes by Using In Chemico and In Vitro Methods in Combination with GC-MS/MS Analysis	29
The Use of Human Tissues for Research: What Investigators Need to Know	24
Conference Diary	23
The Development of an Animal Product-free, Precision-cut Lung Slice Cryopreservation and Post-thaw Culture Method	22
Toxicological Profiling of Potential Shikimate Kinase Inhibitors Against Mycobacterium tuberculosis	16
Combinatorial induction with valproic acid and fibroblast growth factor-9 enhances neural differentiation and cell fate commitment in adipose tissue-derived mesenchymal stem cells	15
Conference Diary	11
A History of the Development of Alternatives to Animals in Research and Testing	11
Progress and Remaining Opportunities to Increase the Use of Animal-free Antibodies in the USA	11
Brazilian National Network of Alternative Methods (RENAMA) 10th Anniversary: Meeting of the Associated Laboratories, May 2022	10
Editorial	9
Dr Manfred Liebsch: Former Head of ZEBET and ATLA Editorial Board Member	9
Development of Sensitive In Vitro Protocols for the Biocompatibility Testing of Medical Devices and Pharmaceuticals Intended for Contact with the Eyes: Acute Irritation and Phototoxicity Assess	9
Resources Round-up	9
Report of the First ONTOX Stakeholder Network Meeting: Digging Under the Surface of ONTOX Together With the Stakeholders	9
In Silico Prediction of Human Clinical Pharmacokinetics with ANDROMEDA by Prosilico: Predictions for an Established Benchmarking Data Set, a Modern Small Drug Data Set, and a Comparison with La	8
The Rise of Three Rs Centres and Platforms in Europe*	8
Spotlight on Three Rs Progress	7
The 19th FRAME Annual Lecture, November 2022: Safer Chemicals and Sustainable Innovation Will Be Achieved by Regulatory Use of Modern Safety Science, Not by More Animal Testing	7
Editorial	7
2021 Michael Balls Award	7
Resources Round-up	7

Editorial	7
Addressing Animal Welfare Issues in Fetal Blood Collection for Fetal Bovine Serum Production	6
Fenugreek Seed Extract Regulates Human Umbilical Vein Endothelial Cell Angiogenesis and Proliferation via the PI3K/Akt/Cyclin D1 Pathway	6
Thanks to Reviewers	5
Reviewing Current Guidance for the ‘R’ of Replacement and Rethinking it with the ‘Replacement Checklist’	5
The Numbers of Animals Used in Mexico for Scientific and Educational Purposes	4
Editorial	4
Corrigendum to Case Studies Exemplifying the Transition to Animal Component-Free Cell Culture	4
Editorial	4
Editorial	4
Resources Round-up	4
Development of Two Korean IACUC Guidance Documents to Foster Implementation of the Three Rs	4
Editorial	4
Optimisation of a Method for the Differentiation of Human Umbilical Cord-derived Mesenchymal Stem Cells Toward Renal Epithelial-like Cells	4
A Cytotoxicity Assay as an Alternative to the Murine Model for the Potency Testing of Bothrops jararaca Venom and Antivenom: An Intralaboratory Pre-validation Study	4
Accelerating Animal Replacement: How Universities Can Lead — Results of a One-Day Expert Workshop in Zurich, Switzerland	3
Case Studies Exemplifying the Transition to Animal Component-free Cell Culture	3
Editorial	3
Spotlight on Three Rs Progress	3
Spotlight on Three Rs Progress	3
Editorial	3
Conference Diary	3
A New ATLA Associate Editor	3
Editorial	3
JRC Summer School 2021	3
Editorial	3
Advances in Animal Models and Cutting-Edge Research in Alternatives: Proceedings of the Second International Conference on 3Rs Research and Progress, Hyderabad, 2021	2
The Use of 3-D Models of Echocardiographic Imaging Planes for Teaching Echocardiography Techniques for Use in Dogs and Cats	2
Spotlight on Three Rs Progress	2
Use of the Allium cepa Model to Assess the Cytogenotoxicity of Luffariella herdmani Marine Sponge Extract	2
Transparency in Non-Technical Project Summaries to Promote the Three Rs in Respiratory Disease Research	2
Lessons for the Future of NAMs from History, Philosophy and Social Studies of Science	2
The Current Status and Work of Three Rs Centres and Platforms in Europe*	2
ATLA Best Poster Award	2
Editorial	2
Journeying Through Journals: The Publishing Process and How to Maximise Research Impact	2
The Application of New Approach Methodologies in Respiratory Disease Research: Their Role in Improving Translational Medicine from Bench to Bedside	2
Determining the pathogenicity of uropathogenic Escherichia coli strains in the Galleria mellonella larvae model	2
Introducing the COST Action ‘Improving the Quality of Biomedical Science with 3Rs Concepts’ (IMPROVE)	2
Modelling the Sorafenib-resistant Liver Cancer Microenvironment by Using 3-D Spheroids	2
An Evaluation of the Replacement of Animal-derived Biomaterials in Human Primary Cell Culture	2
Resources Round-up	2