OOIR: Observatory of International Research

Papers

(The TQCC of Atla-Alternatives to Laboratory Animals is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
2023 Michael Balls Award	61
Resources Round-up	35
Coculture of ARPE-19 Cells and Porcine Neural Retina as an Ex Vivo Retinal Model	33
Conference Diary	28
A Low-fidelity Simulator for the Development of Vascular Ligation Skills	27
In Silico Prediction of Eye Irritation Using Hansen Solubility Parameters and Predicted pKa Values	25
Spotlight on Three Rs Progress	23
Conference Diary	21
In Vitro Dengue Virus Inhibition by Aqueous Extracts of Aegle marmelos, Munronia pinnata and Psidium guajava	20
Academic Training to Promote the Implementation of Alternative Methods and the Three Rs in the Field of Toxicology	13
Conference Diary	12
A History of the Development of Alternatives to Animals in Research and Testing	10
A Comparison of European Union and Turkish Reports on the Statistics of Experimental Animal Use in Toxicity Testing	10
Conference Diary	9
Editorial	9
Editorial	8
A Human Cell-based Assay to Assess the Induction of Vasculature Formation for Non-genotoxic Carcinogenicity Testing Purposes: A Pilot Study	8
Extension of the Virtual Cell Based Assay from a 2-D to a 3-D Cell Culture Model	8
JRC Summer School 2021	8
Editorial	7
The Evolution of Regulatory Toxicology: Where is the Gardener?	7
Editorial	7
The Use of Human Tissues for Research: What Investigators Need to Know	7
Spotlight on Three Rs Progress	7
Spotlight on Three Rs Progress	6

Editorial	6
An Accessible Nephrectomy and Cystotomy Simulator for Use in Teaching Small Animal Surgery	6
Spotlight on Three Rs Progress	6
Comparison of Long-term Human Precision-cut Lung Slice Culture Methodology and Response to Challenge: An Argument for Standardisation	6
An Evaluation of Different Types of Peptone as Partial Substitutes for Animal-derived Serum in Vero Cell Culture	5
The VEGAHUB Platform: The Philosophy and the Tools	5
Resources Round-up	5
Case Studies Exemplifying the Transition to Animal Component-free Cell Culture	4
Resources Round-up	4
The Safety Assessment of Cosmetic Perfumes by Using In Chemico and In Vitro Methods in Combination with GC-MS/MS Analysis	4
Editorial	4
Spotlight on Three Rs Progress	4
Conference Diary	4
Accelerating Animal Replacement: How Universities Can Lead — Results of a One-Day Expert Workshop in Zurich, Switzerland	4
Editorial	3
Thanks to Reviewers	3
Spotlight on Three Rs Progress	3
Spotlight on Three Rs Progress	3
Spotlight on Three Rs Progress	3
Cigarette Smoke Constituents and Nicotine Differentially Affect Cytokine Production by Human Macrophages Stimulated by TLR Ligands In Vitro: Considerations for a Standardised Protocol	3
JRC Summer School on Non-animal Approaches in Science, May 2021	3
Adapting to Changes in Publishing When Searching for Alternatives and Reporting on Animal Research: A Librarian’s Perspective	3
Editorial	3
Is UK Animal Research Governance Facing a ‘New Normal’? Considering the Risks and Benefits of ‘Going Online’	3
Resources Round-up	3
The Development and Evaluation of Brain and Heart Cell Lines from a Marine Fish for Use in Xenobiotic-Induced Cytotoxicity Testing	2
Conference Diary	2
The Use of MPS in Three Rs and Regulatory Applications: Perspectives From Developers on Stakeholder Responsibilities	2
Chemicals 2.0 and Why We Need to Bypass the Gold Standard in Regulatory Toxicology	2
Resources Round-up	2
The Effects of Urolithin B and Auraptene on Quinolinic Acid-induced Toxicity in the SH-SY5Y Neuroblastoma Cell Line	2
Spotlight on Three Rs Progress	2
Towards More Human and Humane Testing: The Role of the Device Supplier Industry	2
Toxicological Profiling of Potential Shikimate Kinase Inhibitors Against Mycobacterium tuberculosis	2
Upholding the EU's Commitment to ‘Animal Testing as a Last Resort' Under REACH Requires a Paradigm Shift in How We Assess Chemical Safety to Close the Gap Between Regulatory Testing and Modern Safety	2
Conference Diary	2
Conference Diary	2
Editorial	2
Barriers to the Use of Recombinant Bacterial Endotoxins Test Methods in Parenteral Drug, Vaccine and Device Safety Testing	2
Report of the First ONTOX Hackathon: Hack to Save Lives and Avoid Animal Suffering. The Use of Artificial Intelligence in Toxicology — A Potential Driver for Reducing/Replacing Laboratory Animals in t	2