OOIR: Observatory of International Research

Papers

(The TQCC of Cell Biochemistry and Function is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
A review of myocardial ischaemia/reperfusion injury: Pathophysiology, experimental models, biomarkers, genetics and pharmacological treatment	63
Ageing and mesenchymal stem cells derived exosomes: Molecular insight and challenges	62
Computational targeting of allosteric site of MEK1 by quinoline‐based molecules	49
The role of Shh signalling pathway in central nervous system development and related diseases	40
Cystine‐glutamate antiporter xCT as a therapeutic target for cancer	37
Photobiomodulation in diabetic wound healing: A review of red and near‐infrared wavelength applications	32
Molecular insights of NADPH oxidases and its pathological consequences	29
Inhibition of nonstructural protein 15 of SARS‐CoV‐2 by golden spice: A computational insight	28
Increased ABCC2 expression predicts cisplatin resistance in non‐small cell lung cancer	26
Phenolic compounds as antidiabetic, anti‐inflammatory, and anticancer agents and improvement of their bioavailability by liposomes	25
LINC00240 promotes gastric cancer cell proliferation, migration and EMT via the miR‐124‐3p / DNMT3B axis	23
ATG5: A central autophagy regulator implicated in various human diseases	23
Gene therapy: A promising approach for breast cancer treatment	23
MiRNAs as potential biomarker of kidney diseases: A review	23
Is there a link between vitamin D status, SARS‐CoV‐2 infection risk and COVID‐19 severity?	22
Angiogenesis induction in breast cancer: A paracrine paradigm	21
Oxidative stress‐A direct bridge to central nervous system homeostatic dysfunction and Alzheimer's disease	21
Mammalian target of rapamycin (mTOR) signaling pathway and traumatic brain injury: A novel insight into targeted therapy	21
Overexpression of microRNA‐23a‐5p induces myocardial infarction by promoting cardiomyocyte apoptosis through inhibited of PI3K/AKT signalling pathway	19
Myogenic, genomic and non‐genomic influences of the vitamin D axis in skeletal muscle	19
Expression of Concern: LncRNA TUG1 facilitates proliferation, invasion and stemness of ovarian cancer cell via miR‐186‐5p/ZEB1 axis	19
Ovarian cancer derived PKR1 positive exosomes promote angiogenesis by promoting migration and tube formation in vitro	18
Ischaemic preconditioning‐induced serum exosomes protect against myocardial ischaemia/reperfusion injury in rats by activating the PI3K/AKT signalling pathway	17
Menstrual blood CD146⁺ mesenchymal stem cells reduced fibrosis rate in the rat model of premature ovarian failure	17
Inhibition of extracellular vesicle biogenesis in tumor cells: A possible way to reduce tumorigenesis	16

Context is key: Understanding the regulation, functional control, and activities of the p53 tumour suppressor	16
LINC‐PINT suppresses tumour cell proliferation, migration and invasion through targeting miR‐374a‐5p in ovarian cancer	15
Immunomodulatory effects of phytosomal curcumin on related‐micro RNAs, CD200 expression and inflammatory pathways in dental pulp stem cells	15
In vitro exosomal transfer of Nrf2 led to the oxaliplatin resistance in human colorectal cancer LS174T cells	15
Bile acid‐based advanced drug delivery systems, bilosomes and micelles as novel carriers for therapeutics	14
Hypoxia as a modulator of cytochromes P450: Overexpression of the cytochromes CYP2S1 and CYP24A1 in human liver cancer cells in hypoxia	14
Inhibin, beta A regulates the transforming growth factor‐beta pathway to promote malignant biological behaviour in colorectal cancer	13
The tumorigenic and therapeutic functions of exosomes in colorectal cancer: Opportunity and challenges	13
A‐kinase‐interacting protein 1 promotes EMT and metastasis via PI3K/Akt/IKKβ pathway in cervical cancer	13
Retracted: Tormentic acid inhibits hepatic stellate cells activation via blocking PI3K/Akt/mTOR and NF‐κB signalling pathways	13
Abnormal neuronal damage and inflammation in the hippocampus of kainic acid‐induced epilepsy mice	13
microRNAs in female infertility: An overview	13
MiR‐140‐5p promotes osteogenic differentiation of mouse embryonic bone marrow mesenchymal stem cells and post‐fracture healing of mice	13
SARS‐COV‐2 (COVID‐19): Cellular and biochemical properties and pharmacological insights into new therapeutic developments	12
Evaluating the effect of secretome of human amniotic mesenchymal stromal cells on apoptosis induction and epithelial‐mesenchymal transition inhibition in LNCaP prostate cancer cells based o	12
Macrophage efferocytosis in health and disease	12
Propofol induces oxidative stress and apoptosis in vitro via regulating miR‐363‐3p/CREB signalling axis	11
Screening of Cu₄O₃ NPs efficacy and its anticancer potential against cervical cancer	11
Semaglutide (GLP‐1 receptor agonist) stimulates browning on subcutaneous fat adipocytes and mitigates inflammation and endoplasmic reticulum stress in visceral fat adipocytes of obese mice	11
Demethyleneberberine promotes apoptosis and suppresses TGF‐β/Smads induced EMT in the colon cancer cells HCT‐116	11
Icariin alleviates MSU‐induced rat GA models through NF‐κB/NALP3 pathway	11
The role of fatty acid amide hydrolase enzyme inhibitors in Alzheimer's disease	11
The involvement of a chemokine receptor antagonist CTCE‐9908 and kynurenine metabolites in cancer development	11
Microarray and in silico analysis of DNA repair genes between human testis of patients with nonobstructive azoospermia and normal cells	11
Genetic and epigenetic control of ACE2 expression and its possible role in COVID‐19	10
DMBT1 suppresses cell proliferation, migration and invasion in ovarian cancer and enhances sensitivity to cisplatin through galectin‐3/PI3k/Akt pathway	10
Melatonin: A smart molecule in the DNA repair system	10
Silence of TPPP3 suppresses cell proliferation, invasion and migration via inactivating NF‐κB/COX2 signal pathway in breast cancer cell	10
ALDH5A1 acts as a tumour promoter and has a prognostic impact in papillary thyroid carcinoma	10
Osteogenic differentiation potential of human bone marrow‐derived mesenchymal stem cells enhanced by bacoside‐A	10
CDC20 inhibitor Apcin inhibits embryo implantation in vivo and in vitro	10
Melatonin alleviates d‐galactose‐decreased hyaluronic acid production in synovial membrane cells via Sirt1 signalling	10
Cellular and molecular mechanism in neurodegeneration: Possible role of neuroprotectants	10
Long non‐coding RNA FAM66C is associated with clinical progression and promotes cell proliferation by inhibiting proteasome pathway in prostate cancer	10
LINC00662 contributes to the progression and the radioresistance of cervical cancer by regulating miR‐497‐5p and CDC25A	10
Could inhibition of metalloproteinases be used to block the process of metastasis?	10
The effect of the “segment” of spinal cord injury on the activity of the nucleotide‐binding domain‐like receptor protein 3 inflammasome and response to hormonal therapy	9
Mesenchymal stem cells repair bone marrow damage of aging rats and regulate autophagy and aging genes	9
Metformin suppresses self‐renewal and stemness of cancer stem cell models derived from pluripotent stem cells	9
Pharmacological inhibition of UPR sensor PERK attenuates HIV Tat‐induced inflammatory M1 phenotype in microglial cells	9
STAT1 determines aggressiveness of glioblastoma both in vivo and in vitro through wnt/β‐catenin signalling pathway	9
Interaction of membrane‐embedded cytochrome b‐complexes with quinols: Classical Q‐cycle and murburn model	9
Trypanosoma cruzi trans‐sialidase induces STAT3 and ERK activation by prokineticin receptor 2 binding	9
TTP488 ameliorates NLRP3‐associated inflammation, viability, apoptosis, and ROS production in an Alzheimer's disease cell model by mediating the JAK1/S	8
Autophagy in tooth: Physiology, disease and therapeutic implication	8
Nonenzymatic glycosylation of isolated human immunoglobulin‐G by D‐ribose	8
Role of marijuana components on the regenerative ability of stem cells	8
Telomerase‐based therapies in haematological malignancies	8
Dieckol induces cell cycle arrest by down‐regulating CDK2/cyclin E in response to p21/p53 activation in human tracheal fibroblasts	8
MicroRNA‐92b acts as an oncogene by targeting PTEN/AKT in NSCLC	8

The protective effect of metformin against testicular damage in diabetes and prostate cancer model	8
Differential mechanisms of autophagy in cancer stem cells: Emphasizing gastrointestinal cancers	8
Simultaneous proteasome and autophagy inhibition synergistically enhances cytotoxicity of doxorubicin in breast cancer cells	8
Sulindac and vitamin D3 synergically inhibit proliferation of MCF‐7 breast cancer cell through AMPK/Akt/β‐catenin axis in vitro	7
Molecular structure, gene expression and functional role of WFDC1 in angiogenesis and cancer	7
Vanillin attenuates thioacetamide‐induced renal assault by direct and indirect mediation of the TGFβ, ERK and Smad signalling pathways in rats	7
Epigenetics and mitochondrial dysfunction insights into the impact of the progression of non‐alcoholic fatty liver disease	7
The mechanisms of lncRNA Tug1 in islet dysfunction in a mouse model of intrauterine growth retardation	7
Characterization of antiapoptotic microRNAs in primary Sjögren's syndrome	7
Potential targets of severe acute respiratory syndrome coronavirus 2 of clinical drug fluvoxamine: Docking and molecular dynamics studies to elucidate viral action	7
Metformin encapsulated gold nanoparticles (MTF‐GNPs): A promising antiglycation agent	7
PTPN6 promotes chemosensitivity of colorectal cancer cells via inhibiting the SP1/MAPK signalling pathway	7
Polycaprolactone‐co‐polylactic acid nanofiber scaffold in combination with 5‐azacytidine and transforming growth factor‐β to induce cardiomyocyte differentiation of adipose‐derived mesenchymal	6
Evidence that cervical cancer cells cultured as tumorspheres maintain high CD73 expression and increase their protumor characteristics through TGF‐β production	6
Cathepsin A regulates pluripotency, proliferation and differentiation in mouse embryonic stem cells	6
The role of Smad4 in the regulation of insulin resistance, inflammation and cell proliferation in HTR8‐Svneo cells	6
Therapeutic role of hesperidin in collagen‐induced rheumatoid arthritis through antiglycation and antioxidant activities	6
S100A6 represses Calu‐6 lung cancer cells growth via inhibiting cell proliferation, migration, invasion and enhancing apoptosis	6
MiR‐302b‐5p enhances the neuroprotective effect of IGF‐1 in methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine‐induced Parkinson's disease by regulating inducible nitric‐oxide synthase	6
Nano‐based methods for novel coronavirus 2019 (2019‐nCoV) diagnosis: A review	6
microRNA‐124‐3p inhibits tumourigenesis by targeting mitogen‐activated protein kinase 4 in papillary thyroid carcinoma	6
Distinct glycolytic pathway regulation in liver, tumour and skeletal muscle of mice with cancer cachexia	6
Application of exosomes for the alleviation of COVID‐19‐related pathologies	6
Long non‐coding RNA FAM83H‐AS1 as an emerging marker for diagnosis, prognosis and therapeutic targeting of cancer	6
Cadherins and the pathogenesis of epilepsy	6
Novel nucleolar localization of clusterin and its associated functions in human oral cancers: An in vitro and in silico analysis	5
The effects of biophysical stimulation on osteogenic differentiation and the mechanisms from ncRNAs	5
NK cell dysfunction is linked with disease severity in SARS‐CoV‐2 patients	5
Functional analysis of mesencephalic astrocyte‐derived neurotrophic factor in retinal ganglion cells under oxidative stress	5
Moving beyond nanotechnology to uncover a glimmer of hope in diabetes medicine: Effective nanoparticle‐based therapeutic strategies for the management and treatment of diabetic foot ulcers	5
Comparative profiles of DNA methylation and differential gene expression in osteocytic areas from aged and young mice	5
HSP90 inhibitors strengthen extracellular ATP‐stimulated synthesis of interleukin‐6 in osteoblasts: Amplification of p38 MAP kinase	5
Antimicrobial peptides derived from microalgae for combating antibiotic resistance: Current status and prospects	5
Biomarker discovery in highly invasive lung cancer cell through proteomics approaches	5
The diterpene Manool extracted from Salvia tingitana lowers free radical production in retinal rod outer segments by inhibiting the extramitochondrial F₁F_o ATP syntha	5
Potential small‐molecule drugs as available weapons to fight novel coronavirus (2019‐nCoV): A review	5
Modulating Nrf2 transcription factor activity: Revealing the regulatory mechanisms of antioxidant defenses during hibernation in 13‐lined ground squirrels	5
CNTs‐CaP/chitosan‐coated AZ91D magnesium alloy extract promoted rat dorsal root ganglia neuron growth via activating ERK signalling pathway	4
Proteomic analysis of thyroid tissue reveals enhanced catabolic activity in Graves' disease compared to toxic multinodular goitre	4
Target‐based virtual screening, computational multiscoring docking and molecular dynamics simulation of small molecules as promising drug candidate affecting kinesin‐like protein KIFC1	4
Structure of PD1 and its mechanism in the treatment of autoimmune diseases	4
Immunological substrates of depressive symptoms in patients with severe obesity: An exploratory study	4
Antiglycation potential of plant based TiO₂ nanoparticle in D‐ribose glycated BSA in vitro	4
Circular RNAs in childhood‐related diseases and cancers: A review	4
BMP11 regulates thermogenesis in white and brown adipocytes	4
Inhibition of TGF‐β type I receptor by SB505124 down‐regulates osteoblast differentiation and mineralization of human mesenchymal stem cells	4
Dynamic expression of H19 and MALAT1 and their correlation with tumor progression biomarkers in a multistage hepatocarcinogenesis model	4
Improved biological behaviours and osteoinductive capacity of the gelatin nanofibers while composites with GO/MgO	4
Cemtirestat, an aldose reductase inhibitor and antioxidant compound, induces ocular defense against oxidative and inflammatory stress in rat models for glycotoxicity	4
Structural and functional insights on vitamin D receptor and CYP24A1 deleterious single nucleotide polymorphisms: A computational and pharmacogenomics perpetual approach	4
Advances on biological functions of exosomal non‐coding RNAs in osteoarthritis	4
Regulatory expression of uncoupling protein 1 and its related genes by endogenous activity of the transforming growth factor‐β family in bovine myogenic cells	4
Effects of mitochondria‐associated Ca²⁺ transporters suppression on oocyte activation	4
Oral administration of botryosphaeran [(1 → 3)(1 → 6)‐β‐d‐glucan] reduces inflammation through modulation of leukocytes and has limited effect on inflammatory nociception	4
Regulation of radiation‐induced liver damage by modulation of SIRT‐1 activity: In vivo rat model	4
Copy number and expression of CEP89, a protein required for ciliogenesis, are increased and predict poor prognosis in patients with ovarian cancer	4
Diphlorethohydroxycarmalol inhibits melanogenesis via protein kinase A/cAMP response element‐binding protein and extracellular signal‐regulated kinase‐mediated microphthalmia‐associated transcription	4
An in vitro investigation of l‐kynurenine, quinolinic acid, and kynurenic acid on B16 F10 melanoma cell cytotoxicity and morphology	4
Biological insights into the rapid tissue regeneration of freshwater crayfish and crustaceans	4