OOIR: Observatory of International Research

Papers

(The H4-Index of Biochemical Journal is 35. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Effect of methyl DNA adducts on 3’-5’ exonuclease activity of human TREX1	758
GLI1 interaction with p300 modulates SDF1 expression in cancer-associated fibroblasts to promote pancreatic cancer cells migration	188
Binding partners regulate unfolding of myosin VI to activate the molecular motor	150
The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and therapeutic implications	120
A curated list of targeted optimized promiscuous ketoreductases (TOP-K)	87
PKA Cβ: a forgotten catalytic subunit of cAMP-dependent protein kinase opens new windows for PKA signaling and disease pathologies	85
Lactate cross-talk in host–pathogen interactions	82
Computational and experimental characterization of the novel ECM glycoprotein SNED1 and prediction of its interactome	76
Kinetics of the multitasking high-affinity Win binding site of WDR5 in restricted and unrestricted conditions	64
Casting iron into the cell fate mold	63
Characterization of the structural determinants of the ubiquitin-dependent proteasomal degradation of human hepatic tryptophan 2,3-dioxygenase	61
Protecting P-type plasma membrane H+-ATPases from ROS	57
Cancer cachexia: molecular mechanism and pharmacological management	54
Insights into the substrate discrimination mechanisms of methyl-CpG-binding domain 4	53
The insulin receptor family and protein kinase B (Akt) are activated in the heart by alkaline pH and α1-adrenergic receptors	52
Into the fold: advances in understanding aPKC membrane dynamics	51
AMP-activated protein kinase activation suppresses leptin expression independently of adipogenesis in primary murine adipocytes	51
Elevated atmospheric carbon dioxide and plant immunity to fungal pathogens: do the risks outweigh the benefits?	47
Pseudouridylation-mediated gene expression modulation	47
Ferroptosis in plants: regulation of lipid peroxidation and redox status	47
Methylglyoxal induces multiple serine phosphorylation in insulin receptor substrate 1 via the TAK1–p38–mTORC1 signaling axis in adipocytes	47
Frequent loss-of-function mutations in the AMPK-α2 catalytic subunit suggest a tumour suppressor role in human skin cancers	46
Claspin haploinsufficiency leads to defects in fertility, hyperplasia and an increased oncogenic potential	42
Mutations in an unrecognized internal NPT2A PDZ motif disrupt phosphate transport and cause congenital hypophosphatemia	42
Classification of Cushing's syndrome PKAc mutants based upon their ability to bind PKI	41

Colonic ketogenesis, a microbiota-regulated process, contributes to blood ketones and protects against colitis in mice	41
The PRL2 Phosphatase Upregulates miR-21 through Activation of the JAK2/STAT3 Pathway to Downregulate the PTEN Tumor Suppressor	41
Structural and functional characterization of a mycobacterial methylenetetrahydrofolate reductase utilizing NADH as the exclusive cofactor	40
Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance	40
Mutagenic incorporation of inosine into DNA via T:I mismatch formation by human DNA polymerase eta (polη)	39
Identification of inhibitors of human ChaC1, a cytoplasmic glutathione degrading enzyme through high throughput screens in yeast	39
Up-regulation of SLC7A11/xCT creates a vulnerability to selenocystine-induced cytotoxicity	38
Aflatoxin biosynthesis regulators AflR and AflS: DNA binding affinity, stoichiometry, and kinetics	38
Abscisic acid triggers vitamin E accumulation by transient transcript activation of VTE5 and VTE6 in sweet cherry fruits	37
A highly conserved ligand-binding site for AccA transporters of antibiotic and quorum-sensing regulator in Agrobacterium leads to a different specificity	37
In search for structural targets for engineering d-amino acid transaminase: modulation of pH optimum and substrate specificity	35
Michael D. Waterfield	35