Natural Product Reports

Article	Citations
Contents list	187
The molecular complexity of terpene biosynthesis in red algae: current state and future perspectives	150
Privileged natural product compound classes for anti-inflammatory drug development	115
Microbial dynamics and Pseudomonas natural product production in milk and dairy products	115
Contents list	89
Front cover	89
Front cover	89
Front cover	82
Microbial polyketides and their roles in insect virulence: from genomics to biological functions	82
Inside front cover	71
Anthrol reductases: discovery, role in biosynthesis and applications in natural product syntheses	68
Gold-catalyzed cyclization and cycloaddition in natural product synthesis	65
Harnessing microbial co-culture to increase the production of known secondary metabolites	64
The role and mechanisms of canonical and non-canonical tailoring enzymes in bacterial terpenoid biosynthesis	64
Natural sesquiterpene quinone/quinols: chemistry, biological activity, and synthesis	63
Back cover	61
Back cover	60
Front cover	58
Back cover	57
Back cover	52
Front cover	52
Contents list	50
Strategies for total synthesis of bispyrrolidinoindoline alkaloids	49
Pitfalls in the structural elucidation of small molecules. A critical analysis of a decade of structural misassignments of marine natural products	48
Cheminformatic analysis of natural product-based drugs and chemical probes	47

The scent chemistry of butterflies	47
Modular polyketide synthase-derived insecticidal agents: from biosynthesis and metabolic engineering to combinatorial biosynthesis for their production	46
A straightforward access to trifluoromethylated natural products through late-stage functionalization	46
Production of high molecular-ordered stilbene oligomers for the study of their biological activity: total synthesis, bio-catalyzed synthesis and production by plant systems	44
Scalemic natural products	43
Recent advances in the synthesis of insect pheromones: an overview from 2013 to 2022	43
Connecting metabolome and phenotype: recent advances in functional metabolomics tools for the identification of bioactive natural products	42
Natural products as anthelmintics: safeguarding animal health	41
Chemical synthesis and functional evaluation of glycopeptides and glycoproteins containing rare glycosyl amino acid linkages	40
Hot off the Press	39
The tryptophan connection: cyclic peptide natural products linkedviathe tryptophan side chain	39
Vallesamidine and schizozygane alkaloids: rearranged monoterpene indole alkaloids and synthetic endeavours	39
Fe(ii) and 2-oxoglutarate-dependent dioxygenases for natural product synthesis: molecular insights into reaction diversity	39
Biosynthesis, regulation, and engineering of natural products from Lysobacter	37
Finding activity through rigidity: syntheses of natural products containing tricyclic bridgehead carbon centers	36
Harmonizing biosynthesis with post-ingestive modifications to understand the ecological functions of plant natural products	36
Structural enzymology of iterative type I polyketide synthases: various routes to catalytic programming	35
Estimating the extent of adulteration of the popular herbs black cohosh, echinacea, elder berry, ginkgo, and turmeric – its challenges and limitations	35
The biosynthetic logic and enzymatic machinery of approved fungi-derived pharmaceuticals and agricultural biopesticides	35
The fungal natural product class of the sorbicillinoids: structures, bioactivities, biosynthesis, and synthesis	34
Silybin and its congeners: from traditional medicine to molecular effects	34
Terpenoids of plants from Chloranthaceae family: chemistry, bioactivity, and synthesis	33
Structure, properties of gossypol and its derivatives—from physiological activities to drug discovery and drug design	33
Euphorbiaditerpenoids: isolation, structure, bioactivity, biosynthesis, and synthesis (2013–2021)	32
Natural withanolides, an update	32
Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis	31
Functions and biosynthesis of plant signaling metabolites mediating plant–microbe interactions	31
The isolation of water-soluble natural products – challenges, strategies and perspectives	30
Unleashing the potential: type I CRISPR-Cas systems in actinomycetes for genome editing	30
Bacterial cyclophane-containing RiPPs from radical SAM enzymes	28
Recent asymmetric synthesis of natural products bearing an α-tertiary amine moiety via temporary chirality induction strategies	27
Structural diversity, hypothetical biosynthesis, chemical synthesis, and biological activity ofGanodermameroterpenoids	27
A critical review on the use of DP4+ in the structural elucidation of natural products: the good, the bad and the ugly. A practical guide	27
Back cover	27
Contents list	26
Back cover	26
Front cover	26
Front cover	26
Curiouser and curiouser: progress in understanding the programming of iterative highly-reducing polyketide synthases	26
‘Need for speed: high throughput’ – mass spectrometry approaches for high-throughput directed evolution screening of natural product enzymes	26
Correction: Hot off the Press	25
Current and emerging tools and strategies for the identification of bioactive natural products in complex mixtures	25
Front cover	25
Correction: The ‘emodin family’ of fungal natural products–amalgamating a century of research with recent genomics-based advances	25
Front cover	24
Unlocking hidden treasures: the evolution of high-throughput mass spectrometry in screening for cryptic natural products	24
Front cover	24
Simple phenylpropanoids: recent advances in biological activities, biosynthetic pathways, and microbial production	24
Warfare under the waves: a review of bacteria-derived algaecidal natural products	24
Back cover	23

Contents list	23
Front cover	23
Front cover	23
Sesterterpenoids: sources, structural diversity, biological activity, and data management	22
Front cover	22
Inside front cover	22
Contents list	22
Back cover	22
Human milk as a complex natural product	21
Unveiling Amaryllidaceae alkaloids: from biosynthesis to antiviral potential – a review	21
Small animals with unique chemistry – the natural product chemistry of Collembola	21
Streptomyces cell-free systems for natural product discovery and engineering	21
Biosynthesis and bioactivities of microbial genotoxin colibactins	20
Hot off the press	20
Effective data visualization strategies in untargeted metabolomics	20
Trends of antimalarial marine natural products: progresses, challenges and opportunities	20
The chemical ecology of the fungus-farming termite symbiosis	20
Recent ring distortion reactions for diversifying complex natural products	19
Introduction to engineering the biosynthesis of fungal natural products	19
Revisiting the manzamine biosynthetic hypothesis	19
Hot off the Press	18
Strategies and tactics for the synthesis of lipid I and II and shortened analogues: functional building blocks of bacterial cell wall biosynthesis	18
The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide	18
Therapeutic vulnerabilities of cancer stem cells and effects of natural products	18
Industrial total synthesis of natural medicines	18
Analytical methods for the analysis of volatile natural products	18
Hot off the press	17
Bacterial polyynes uncovered: a journey through their bioactive properties, biosynthetic mechanisms, and sustainable production strategies	17
Medicinal plant resin natural products: structural diversity and biological activities	17
Recent advances in the total synthesis of galantamine, a natural medicine for Alzheimer's disease	17
Hot off the Press	16
Hot off the Press	16
Siccanin-related drimane meroterpenoids: biological activities and synthesis	16
Recent advances in total synthesis of protoberberine and chiral tetrahydroberberine alkaloids	16
Human microbiota peptides: important roles in human health	16
Structural diversity, evolutionary origin, and metabolic engineering of plant specialized benzylisoquinoline alkaloids	16
The action of phytochemicals in biofilm control	15
Dynamic environmental interactions shaped by vegetative plant volatiles	15
Structure, synthesis, biosynthesis, and activity of the characteristic compounds fromGinkgo bilobaL.	15
The expanding CRISPR toolbox for natural product discovery and engineering in filamentous fungi	15
Unusually cyclized triterpenoids: occurrence, biosynthesis and chemical synthesis	15
Discovery, bioactivity and biosynthesis of fungal piperazines	15
Advances, opportunities, and challenges in methods for interrogating the structure activity relationships of natural products	15
Plant biosynthetic gene clusters in the context of metabolic evolution	15
Secondary metabolites from mangrove-associated fungi: source, chemistry and bioactivities	14
Opportunities and challenges of RiPP-based therapeutics	14
Biosynthesis, evolution and ecology of microbial terpenoids	14
Purine nucleoside antibiotics: recent synthetic advances harnessing chemistry and biology	14
Dehydroamino acid residues in bioactive natural products	13
Marine natural products	13
S-Adenosylmethionine: more than just a methyl donor	13
The ‘emodin family’ of fungal natural products–amalgamating a century of research with recent genomics-based advances	12
Front cover	12
Back cover	12
Front cover	12
Contents list	11
Contents list	11
Front cover	11
Back cover	11
Inside front cover	11
Contents list	10
Back cover	10
Contents list	10
Front cover	10
Front cover	9
Front cover	9
Back cover	9
Back cover	9
Back cover	8
Contents list	8
Advanced crystallography for structure determination of natural products	8
Front cover	8
Back cover	8
Contents list	8
Contents list	8
Enzymatic ester bond formation strategies in fungal macrolide skeletons	8
Contents list	8
Back cover	8
Contents list	7
Correction: Dearomative logic in natural product total synthesis	7

Non-peptide secondary metabolites from poisonous mushrooms: overview of chemistry, bioactivity, and biosynthesis	7
Back cover	7
Norditerpenoid alkaloids from Aconitum and Delphinium: structural relevance in medicine, toxicology, and metabolism	7
Contents list	7
Antarctic bacterial natural products: from genomic insights to drug discovery	7
Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic	7
Recent advances in the synthesis of ent-kaurane diterpenoids	6
Egg toxic compounds in the animal kingdom. A comprehensive review	6
Cyanophycin and its biosynthesis: not hot but very cool	6
Strychnine and its mono- and dimeric analogues: a pharmaco-chemical perspective	6
Hot off the press	6
Correction: The ins and outs of transporters at plasma membrane and tonoplast in plant specialized metabolism	6
Maleidride biosynthesis – construction of dimeric anhydrides – more than just heads or tails	6
Hot off the Press	6
The phosphate ester group in secondary metabolites	6
Recent strategies and tactics for the enantioselective total syntheses of cyclolignan natural products	6
Hot off the Press	6
Future antimalarials fromArtemisia? A rationale for natural product mining against drug-refractoryPlasmodiumstages	6
Chemical synthesis in competition with global genome mining and heterologous expression for the preparation of dimeric tryptophan-derived 2,5-dioxopiperazines	6
Huperzine alkaloids: forty years of total syntheses	5
Hot off the Press	5
Intramolecular cycloaddition of nitrones in total synthesis of natural products	5
Marine indole alkaloid diversity and bioactivity. What do we know and what are we missing?	5
Recent advances in the biosynthetic studies of bacterial organoarsenic natural products	5
Plant-based engineering for production of high-valued natural products	5
Biosynthesis of fungal polyketides by collaborating and trans-acting enzymes	5
Exploring nature's battlefield: organismic interactions in the discovery of bioactive natural products	5
Debottlenecking cytochrome P450-dependent metabolic pathways for the biosynthesis of commercial natural products	5
Natural nematicidal metabolites and advances in their biocontrol capacity on plant parasitic nematodes	5
Verticillins: fungal epipolythiodioxopiperazine alkaloids with chemotherapeutic potential	4
Plant (di)terpenoid evolution: from pigments to hormones and beyond	4
Research progress of meliaceous limonoids from 2011 to 2021	4
Integrative omics approaches for biosynthetic pathway discovery in plants	4
Chemistry, bioactivity, biosynthesis, and total synthesis of stemmadenine alkaloids	3
A chemoinformatic analysis on natural glycosides with respect to biological origin and structural class	3
Natural ten-membered lactones: sources, structural diversity, biological activity, and intriguing future	3
Strategies for the discovery of potential anticancer agents from plants collected from Southeast Asian tropical rainforests as a case study	3
Current status of secondary metabolite pathways linked to their related biosynthetic gene clusters in Aspergillus section Nigri	3
Dearomative logic in natural product total synthesis	3
Chemoenzymatic approaches to plant natural product inspired compounds	3
Marine natural products	3
Recent advances in the synthesis of natural products containing the phloroglucinol motif	3
Marine natural products	3
Contents list	2
Marine paralytic shellfish toxins: chemical properties, mode of action, newer analogues, and structure–toxicity relationship	2
Anti-mycobacterial natural products and mechanisms of action	2
Subterranean marvels: microbial communities in caves and underground mines and their promise for natural product discovery	2
Machine learning-assisted structure annotation of natural products based on MS and NMR data	2
The incredible story of ophiobolin A and sphaeropsidin A: two fungal terpenes from wilt-inducing phytotoxins to promising anticancer compounds	2
Medium-sized peptides from microbial sources with potential for antibacterial drug development	2
The cytochalasans: potent fungal natural products with application from bench to bedside	2
Nitrile biosynthesis in nature: how and why?	2
The beauty of biocatalysis: sustainable synthesis of ingredients in cosmetics	2
The role ofCaenorhabditis elegansin the discovery of natural products for healthy aging	2