OOIR: Observatory of International Research

Papers

(The TQCC of Natural Product Reports is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Contents list	187
The molecular complexity of terpene biosynthesis in red algae: current state and future perspectives	150
Microbial dynamics and Pseudomonas natural product production in milk and dairy products	115
Privileged natural product compound classes for anti-inflammatory drug development	115
Front cover	89
Front cover	89
Contents list	89
Front cover	82
Microbial polyketides and their roles in insect virulence: from genomics to biological functions	82
Inside front cover	71
Anthrol reductases: discovery, role in biosynthesis and applications in natural product syntheses	68
Gold-catalyzed cyclization and cycloaddition in natural product synthesis	65
The role and mechanisms of canonical and non-canonical tailoring enzymes in bacterial terpenoid biosynthesis	64
Harnessing microbial co-culture to increase the production of known secondary metabolites	64
Natural sesquiterpene quinone/quinols: chemistry, biological activity, and synthesis	63
Back cover	61
Back cover	60
Front cover	58
Back cover	57
Back cover	52
Front cover	52
Contents list	50
Strategies for total synthesis of bispyrrolidinoindoline alkaloids	49
Pitfalls in the structural elucidation of small molecules. A critical analysis of a decade of structural misassignments of marine natural products	48
The scent chemistry of butterflies	47

Cheminformatic analysis of natural product-based drugs and chemical probes	47
Modular polyketide synthase-derived insecticidal agents: from biosynthesis and metabolic engineering to combinatorial biosynthesis for their production	46
A straightforward access to trifluoromethylated natural products through late-stage functionalization	46
Production of high molecular-ordered stilbene oligomers for the study of their biological activity: total synthesis, bio-catalyzed synthesis and production by plant systems	44
Recent advances in the synthesis of insect pheromones: an overview from 2013 to 2022	43
Scalemic natural products	43
Connecting metabolome and phenotype: recent advances in functional metabolomics tools for the identification of bioactive natural products	42
Natural products as anthelmintics: safeguarding animal health	41
Chemical synthesis and functional evaluation of glycopeptides and glycoproteins containing rare glycosyl amino acid linkages	40
The tryptophan connection: cyclic peptide natural products linkedviathe tryptophan side chain	39
Vallesamidine and schizozygane alkaloids: rearranged monoterpene indole alkaloids and synthetic endeavours	39
Fe(ii) and 2-oxoglutarate-dependent dioxygenases for natural product synthesis: molecular insights into reaction diversity	39
Hot off the Press	39
Biosynthesis, regulation, and engineering of natural products from Lysobacter	37
Finding activity through rigidity: syntheses of natural products containing tricyclic bridgehead carbon centers	36
Harmonizing biosynthesis with post-ingestive modifications to understand the ecological functions of plant natural products	36
Estimating the extent of adulteration of the popular herbs black cohosh, echinacea, elder berry, ginkgo, and turmeric – its challenges and limitations	35
The biosynthetic logic and enzymatic machinery of approved fungi-derived pharmaceuticals and agricultural biopesticides	35
Structural enzymology of iterative type I polyketide synthases: various routes to catalytic programming	35
Silybin and its congeners: from traditional medicine to molecular effects	34
The fungal natural product class of the sorbicillinoids: structures, bioactivities, biosynthesis, and synthesis	34
Structure, properties of gossypol and its derivatives—from physiological activities to drug discovery and drug design	33
Terpenoids of plants from Chloranthaceae family: chemistry, bioactivity, and synthesis	33
Euphorbiaditerpenoids: isolation, structure, bioactivity, biosynthesis, and synthesis (2013–2021)	32
Natural withanolides, an update	32
Functions and biosynthesis of plant signaling metabolites mediating plant–microbe interactions	31
Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis	31
Unleashing the potential: type I CRISPR-Cas systems in actinomycetes for genome editing	30
The isolation of water-soluble natural products – challenges, strategies and perspectives	30
Bacterial cyclophane-containing RiPPs from radical SAM enzymes	28
Structural diversity, hypothetical biosynthesis, chemical synthesis, and biological activity ofGanodermameroterpenoids	27
A critical review on the use of DP4+ in the structural elucidation of natural products: the good, the bad and the ugly. A practical guide	27
Back cover	27
Recent asymmetric synthesis of natural products bearing an α-tertiary amine moiety via temporary chirality induction strategies	27
Front cover	26
Front cover	26
Curiouser and curiouser: progress in understanding the programming of iterative highly-reducing polyketide synthases	26
‘Need for speed: high throughput’ – mass spectrometry approaches for high-throughput directed evolution screening of natural product enzymes	26
Contents list	26
Back cover	26
Current and emerging tools and strategies for the identification of bioactive natural products in complex mixtures	25
Front cover	25
Correction: The ‘emodin family’ of fungal natural products–amalgamating a century of research with recent genomics-based advances	25
Correction: Hot off the Press	25
Front cover	24
Simple phenylpropanoids: recent advances in biological activities, biosynthetic pathways, and microbial production	24
Warfare under the waves: a review of bacteria-derived algaecidal natural products	24
Front cover	24
Unlocking hidden treasures: the evolution of high-throughput mass spectrometry in screening for cryptic natural products	24
Contents list	23

Front cover	23
Front cover	23
Back cover	23
Inside front cover	22
Contents list	22
Back cover	22
Sesterterpenoids: sources, structural diversity, biological activity, and data management	22
Front cover	22
Unveiling Amaryllidaceae alkaloids: from biosynthesis to antiviral potential – a review	21
Small animals with unique chemistry – the natural product chemistry of Collembola	21
Streptomyces cell-free systems for natural product discovery and engineering	21
Human milk as a complex natural product	21
Hot off the press	20
Effective data visualization strategies in untargeted metabolomics	20
Trends of antimalarial marine natural products: progresses, challenges and opportunities	20
The chemical ecology of the fungus-farming termite symbiosis	20
Biosynthesis and bioactivities of microbial genotoxin colibactins	20
Introduction to engineering the biosynthesis of fungal natural products	19
Revisiting the manzamine biosynthetic hypothesis	19
Recent ring distortion reactions for diversifying complex natural products	19
The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide	18
Therapeutic vulnerabilities of cancer stem cells and effects of natural products	18
Industrial total synthesis of natural medicines	18
Analytical methods for the analysis of volatile natural products	18
Hot off the Press	18
Strategies and tactics for the synthesis of lipid I and II and shortened analogues: functional building blocks of bacterial cell wall biosynthesis	18
Medicinal plant resin natural products: structural diversity and biological activities	17
Recent advances in the total synthesis of galantamine, a natural medicine for Alzheimer's disease	17
Hot off the press	17
Bacterial polyynes uncovered: a journey through their bioactive properties, biosynthetic mechanisms, and sustainable production strategies	17