Journal of Cerebral Blood Flow and Metabolism

Article	Citations
Vascular synthesis based on hemodynamic efficiency principle recapitulates measured cerebral circulation properties in the human brain	152
Resuscitation with epinephrine worsens cerebral capillary no-reflow after experimental pediatric cardiac arrest: An in vivo multiphoton microscopy evaluation	81
Dysmaturation of sleep state and electroencephalographic activity after hypoxia-ischaemia in preterm fetal sheep	79
Targeting Pdzrn3 maintains adult blood-brain barrier and central nervous system homeostasis	54
SIRT1 mediates hypoxic postconditioning- and resveratrol-induced protection against functional connectivity deficits after subarachnoid hemorrhage	49
Thanks to Reviewers	49
Defining cerebral leukocyte populations in local ischemic blood samples from patients with hyperacute stroke	46
An update on stem cell therapy for stroke patients: Where are we now?	43
Hyperperfusion profiles after recanalization differentially associate with outcomes in a rat ischemic stroke model	42
Dialysis adequacy and hemoglobin levels predict cerebral atrophy in maintenance-hemodialysis patients	42
Glyceryl trinitrate for the treatment of ischaemic stroke: Determining efficacy in rodent and ovine species for enhanced clinical translation	41
The relative associations of aortic and carotid artery stiffness with CeVD and cognition	39
Microglial histone deacetylase 2 is dispensable for functional and histological outcomes in a mouse model of traumatic brain injury	39
Oxidative stress and chronic cerebral hypoperfusion: An overview from preclinical rodent models	38
Retinal capillary microvessel morphology changes are associated with vascular damage and dysfunction in cerebral small vessel disease	37
Alterations of the blood-brain barrier during aging	36
The brain’s “dark energy” puzzle: How strongly is glucose metabolism linked to resting-state brain activity?	36
Differential pial and penetrating arterial responses examined by optogenetic activation of astrocytes and neurons	36
Nicotinamide phosphoribosyltransferase inhibitor ameliorates mouse aging-induced cognitive impairment	35
The lateral entorhinal cortex is a hub for local and global dysfunction in early Alzheimer’s disease states	34
Critical role of Slc22a8 in maintaining blood-brain barrier integrity after experimental cerebral ischemia-reperfusion	34
Brain PET imaging using 11C-flumazenil and 11C-buprenorphine does not support the hypothesis of a mutual interaction between buprenorphine and benzodiazepines at the neurorecepto	34
CNS resident macrophages enhance dysfunctional angiogenesis and circulating monocytes infiltration in brain arteriovenous malformation	34
Gut microbiota-associated metabolites and risk of ischemic stroke in REGARDS	33
Imaging features of adult moyamoya disease patients with anterior intracerebral hemorrhage based on high-resolution magnetic resonance imaging	32

Agomelatine promotes differentiation of oligodendrocyte precursor cells and preserves white matter integrity after cerebral ischemic stroke	31
Differential regulation of oxidative stress, microbiota-derived, and energy metabolites in the mouse brain during sleep	30
Point/counterpoint: We should not take the direction of blood pressure change into consideration for dynamic cerebral autoregulation quantification	30
Control of neurovascular coupling by ATP-sensitive potassium channels	29
The many layers of BOLD. The effect of hypercapnic and hyperoxic stimuli on macro- and micro-vascular compartments quantified by CVR, M, and CBV across cortical depth	29
Profound changes in cerebrospinal fluid proteome and metabolic profile are associated with congenital hydrocephalus	29
Non-classical monocytes promote neurovascular repair in cerebral small vessel disease associated with microinfarctions via CX3CR1	29
Dynamic cerebral autoregulation measured by diffuse correlation spectroscopy	29
Machine learning based analysis of stroke lesions on mouse tissue sections	28
CO2 cerebrovascular reactivity measured with CBF-MRI in older individuals: Association with cognition, physical function, amyloid and tau proteins	28
Rethinking animal attrition in preclinical research: Expressing causal mechanisms of selection bias using directed acyclic graphs	27
Targeted capillary photothrombosis via multiphoton excitation of Rose Bengal	27
Imaging quantitative changes in blood-brain barrier permeability using [18F]2-fluoro-2-deoxy-sorbitol ([18F]FDS) PET in relation to glial cell recruitment in a mouse model of end	27
Association between electroencephalogram alpha-band oscillations and executive and processing functions in patients with cerebral small vessel diseases	27
Reduced coupling of global brain function and cerebrospinal fluid dynamics in Parkinson’s disease	26
Mitochondrial ferritin upregulation by deferiprone reduced neuronal ferroptosis and improved neurological deficits via NDRG1/Yap pathway in a neonatal rat model of germinal matrix hemorrhage	26
Microglia: Active participants in brain capillary function	26
Chronic sleep fragmentation impairs brain interstitial clearance in young wildtype mice	25
Anesthetics in pathological cerebrovascular conditions	25
[11C]PBR28 radiotracer kinetics are not driven by alterations in cerebral blood flow	25
Cortical spreading depolarization-induced constriction of penetrating arteries can cause watershed ischemia: A potential mechanism for white matter lesions	25
Hypocapnia, eucapnia, and hypercapnia during “Where’s Waldo” search paradigms: Neurovascular coupling across the cardiac cycle and biological sexes	24
Reliability of task-specific neuronal activation assessed with functional PET, ASL and BOLD imaging	24
A dangerous liaison: Spreading depolarization and tissue acidification in cerebral ischemia	24
Altered resting-state cerebral blood flow and functional connectivity mediate suicidal ideation in major depressive disorder	24
NAD+ precursor nutritional supplements sensitize the brain to future ischemic events	24
Proteomic analysis of jugular venous blood in acute large vessel occlusion stroke with futile recanalization	24
Data-based modeling of cerebral hemodynamics quantifies impairment of cerebral blood flow regulation in type-2 diabetes	23
Static autoregulation in humans	23
Preserving stroke penumbra by targeting lipid signalling	23
Point-Counterpoint: Transfer function analysis of dynamic cerebral autoregulation: To band or not to band?	23
Commentary to Brain-wide continuous functional ultrasound imaging for real-time monitoring of hemodynamics during ischemic stroke	23
Molecular mechanism of cerebral edema improvement via IL-1RA released from the stroke-unaffected hindlimb by treadmill exercise after cerebral infarction in rats	23
Zfp580 inactivation as a new therapeutic target to enhance recovery after stroke in mice	22
Quantification of monoacylglycerol lipase and its occupancy by an exogenous ligand in rhesus monkey brains using [18F]T-401 and PET	22
Antihypertensives in dementia: Good or bad for the brain?	22
Activation of lactate receptor HCAR1 down-modulates neuronal activity in rodent and human brain tissue	22
Sigma-1 receptor signaling: A potential therapeutic approach for ischemic stroke	22
Brain-derived programmed death-ligand 1 mediates immunosuppression post intracerebral hemorrhage	22
Cpeb4-mediated Dclk2 promotes neuronal pyroptosis induced by chronic cerebral ischemia through phosphorylation of Ehf	22
A cluster of blood-based protein biomarkers reflecting coagulation relates to the burden of cerebral small vessel disease	21
Early stopping in clinical PET studies: How to reduce expense and exposure	21
Calcium transients in nNOS neurons underlie distinct phases of the neurovascular response to barrel cortex activation in awake mice	21
RETRACTION NOTICE: Vagus nerve mediates the protective effects of melanocortins against cerebral and systemic damage after ischemic stroke	21
Glucose sparing by glycogenolysis (GSG) determines the relationship between brain metabolism and neurotransmission	21
Wdfy3 regulates glycophagy, mitophagy, and synaptic plasticity	21
The cholinergic system modulates negative BOLD responses in the prefrontal cortex once electrical perforant pathway stimulation triggers neuronal afterdischarges in the hippocampus	21
Reversal of the detrimental effects of social isolation on ischemic cerebral injury and stroke-associated pneumonia by inhibiting small intestinal γδ T-cell migration into the brain and lung	21
Inhibition of EphA4 reduces vasogenic edema after experimental stroke in mice by protecting the blood-brain barrier integrity	21
Cohort study on the differential expression of inflammatory and angiogenic factors in thrombi, cerebral and peripheral plasma following acute large vessel occlusion stroke	21

Randomized placebo-controlled trial of CL2020, an allogenic muse cell–based product, in subacute ischemic stroke	21
Evaluating infusion methods and simplified quantification of synaptic density in vivo with [11C]UCB-J and [18F]SynVesT-1 PET	20
Unraveling diurnal and technical variability in cerebral hemodynamics from neurovascular 4D-Flow MRI	20
Dynamic reorganization of cortical structure in multi-domain regions after capsular and pontine stroke	20
Hemodynamic imaging parameters in brain metastases patients – Agreement between multi-delay ASL and hypercapnic BOLD	20
Nox2 underpins microvascular inflammation and vascular contributions to cognitive decline	20
Global, regional and national burden of ischemic stroke attributed to high low-density lipoprotein cholesterol, 1990–2019：A decomposition analysis and age-period-cohort analysis	20
Microglia balances hypermyelination and demyelination in the brain	20
Association of autosomal dominant polycystic kidney disease with cerebral small vessel disease	20
Capillary transit time heterogeneity inhibits cerebral oxygen metabolism in patients with reduced cerebrovascular reserve capacity from steno-occlusive disease	19
Association between occlusion location, net water uptake and ischemic lesion growth in large vessel anterior circulation strokes	19
Tenascin-C induction exacerbates post-stroke brain damage	19
Preclinical in vivo longitudinal assessment of KG207-M as a disease-modifying Alzheimer’s disease therapeutic	19
The negative effect of aging on cerebral venous outflow in acute ischemic stroke	19
Evidence for the beneficial effect of ketamine in the treatment of patients with post-traumatic stress disorder: A systematic review and meta-analysis	19
Amphetamine-induced dopamine release in rat: Whole-brain spatiotemporal analysis with [11C]raclopride and positron emission tomography	18
[11C]deschloroclozapine is an improved PET radioligand for quantifying a human muscarinic DREADD expressed in monkey brain	18
Blood-brain barrier disruption imaging in postoperative cerebral hyperperfusion syndrome using DCE-MRI	18
Neuronal GPR81 regulates developmental brain angiogenesis and promotes brain recovery after a hypoxic ischemic insult	18
Epigenetic mechanisms and potential therapeutic targets in stroke	18
Not open and shut: Complex and prolonged blood-brain barrier responses after stroke	18
No-reflow after recanalization in ischemic stroke: From pathomechanisms to therapeutic strategies	18
Neural cortical organoids from self-assembling human iPSC as a model to investigate neurotoxicity in brain ischemia	17
H3K9 trimethylation dictates neuronal ferroptosis through repressing Tfr1	17
Hemispheric cerebral blood flow predicts outcome in acute small subcortical infarcts	17
Treatment for moyamoya disease with hyperhomocysteinemia	17
Association between the time of day at stroke onset and functional outcome of acute ischemic stroke patients treated with endovascular therapy	16
Activin A alleviates neuronal injury through inhibiting cGAS-STING-mediated autophagy in mice with ischemic stroke	16
Microvascular changes associated with epilepsy: A narrative review	16
Capillary responses to functional and pathological activations rely on the capillary states at rest	16
Endothelial lincRNA-p21 alleviates cerebral ischemia/reperfusion injury by maintaining blood-brain barrier integrity	16
Precision estimates of relative and absolute cerebral blood flow in Alzheimer’s disease and cognitively normal individuals	16
Hemorrhagic stroke-induced subtype of inflammatory reactive astrocytes disrupts blood-brain barrier	16
Altered hemodynamics and vascular reactivity in a mouse model with severe pericyte deficiency	16
Long lasting argon neuroprotection in a non-human primate model of transient endovascular ischemic stroke	16
Intraoperative evaluation of local cerebral hemodynamic change by laser speckle contrast imaging for predicting postoperative cerebral hyperperfusion during STA-MCA bypass in adult patients with moyam	16
Depression, stress and regional cerebral blood flow	16
Effect of the duration of hypertension on white matter structure and its link with cognition	16
Cerebral critical closing pressure and resistance-area product: the influence of dynamic cerebral autoregulation, age and sex	15
Post-stroke brain can be protected by modulating the lncRNA FosDT	15
Aeromedical evacuation-relevant hypobaria following traumatic brain injury in rats contributes to cerebral blood flow depression, altered neurochemistry, and increased neuroinflammation	15
Amyloid-β disrupts unitary calcium entry through endothelial NMDA receptors in mouse cerebral arteries	15
Physiological variables in association with spreading depolarizations in the late phase of ischemic stroke	15
Role of endothelium-pericyte signaling in capillary blood flow response to neuronal activity	15
Vascular contributions to cognitive decline: Beyond amyloid and tau in the Harvard Aging Brain Study	15
Preconditioning with interleukin-1 alpha is required for the neuroprotective properties of mesenchymal stem cells after ischemic stroke in mice	15
Circulating molecules reflect imaging biomarkers of hemorrhage in cerebral cavernous malformations	15
Alterations of cerebrovascular reactivity following pediatric mild traumatic brain injury are independent of neurodevelopmental changes	14
A CBF decrease in the left supplementary motor areas: New insight into postoperative pediatric cerebellar mutism syndrome using arterial spin labeling perfusion MRI	14
Point-Counterpoint: Cerebral perfusion pressure is a high-risk concept	14
Association of cognitive function and hypoperfusion in Moyamoya disease patients without stroke	14
Low neuronal metabolism during isoflurane-induced burst suppression is related to synaptic inhibition while neurovascular coupling and mitochondrial function remain intact	14
The effectiveness and safety of human urinary kallidinogenase in acute ischemic stroke patients undergoing endovascular therapy	14
Duration of spreading depression is the electrophysiological correlate of infarct growth in malignant hemispheric stroke	14
Comparative analysis of peri-nidal cerebral blood flow and metabolism using a novel quantitative 15O-PET method in patients with arteriovenous malformations	14
Shifting concepts of autoregulation: Commentary to ‘Static autoregulation in humans'	14
Cerebral autoregulation in pediatric and neonatal intensive care: A scoping review	14
Predicting cerebral infarction in patients with atrial fibrillation using machine learning: The Fushimi AF registry	14
Reproducibility of findings in modern PET neuroimaging: insight from the NRM2018 grand challenge	14
Differential vulnerability among cell types in the neurovascular unit: Description and mechanisms	14
Depression of dynamic cerebral autoregulation during neural activation: The role of responders and non-responders	14
Mapping oxidative metabolism in the human brain with calibrated fMRI in health and disease	13
Resting-state functional MRI signal fluctuation amplitudes are correlated with brain amyloid-β deposition in patients with mild cognitive impairment	13
Assessing cortical cerebral microinfarcts on iron-sensitive MRI in cerebral small vessel disease	13
Early remodeling and loss of light-induced dilation of retinal small arteries in CADASIL	13
Leveraging Mendelian randomization to inform drug discovery and development for ischemic stroke	13
Predicting brain temperature in humans using bioheat models: Progress and outlook	13
Selective therapeutic cooling: To maximize benefits and minimize side effects related to hypothermia	13
Association between pre-treatment perfusion profile and cerebral edema after reperfusion therapies in ischemic stroke	13
Physical therapy exerts sub-additive and suppressive effects on intracerebral neural stem cell implantation in a rat model of stroke	13
Exploring the relationship between hemodynamics and the immune microenvironment in carotid atherosclerosis: Insights from CFD and CyTOF technologies	13
Unraveling the brain's response to hypoglycemia: Neurovascular coupling	13
Medin, a link between vascular pathology and dementia?	13
Cerebral blood flow and cerebrovascular resistance across the adult lifespan: A multimodality approach	13
Temperature dysregulation during therapeutic hypothermia predicts long-term outcome in neonates with HIE	13
Dynamic neuroreceptor positron emission tomography in non-anesthetized rats using point source based motion correction: A feasibility study with [11C]ABP688	12
Correcting SUVR bias by accounting for radiotracer clearance in tissue: A validation study with [18F]FE-PE2I PET in cross-sectional, test-retest and longitudinal cohorts	12
Hemodynamic responses in the rat hippocampus are simultaneously controlled by at least two independently acting neurovascular coupling mechanisms	12
Assessment of motion and model bias on the detection of dopamine response to behavioral challenge	12
Comparative vulnerability of PET radioligands to partial inhibition of P-glycoprotein at the blood-brain barrier: A criterion of choice?	12

The effect of hypercapnia on the directional sensitivity of dynamic cerebral autoregulation and the influence of age and sex	12
Nogo-A is secreted in extracellular vesicles, occurs in blood and can influence vascular permeability	12
Acute psilocybin and ketanserin effects on cerebral blood flow: 5-HT2AR neuromodulation in healthy humans	12
The miR-451a facilitates natural killer cell-associated immune deficiency after ischemic stroke	12
Effect of vascular amyloid on white matter disease is mediated by vascular dysfunction in cerebral amyloid angiopathy	12
Aging affects the mouse brain in a region-specific manner	12
Metabolite transport across central nervous system barriers	12
High-physiological and supra-physiological 1,2-13C2 glucose focal supplementation to the traumatised human brain	12
Cerebral ischemia in the developing brain	12
Determining the effects of elevated partial pressure of oxygen on hypercapnia-induced cerebrovascular reactivity	12
CD31 as a probable responding and gate-keeping protein of the blood-brain barrier and the risk of Alzheimer’s disease	12
Neuroinflammation and blood-brain barrier breakdown in acute, clinical intracerebral hemorrhage	12
Tissue-type plasminogen activator induces TNF-α-mediated preconditioning of the blood-brain barrier	12
Female-specific neuroprotection after ischemic stroke by vitronectin-focal adhesion kinase inhibition	12
Novel voxelwise residual analysis of [11C]raclopride PET data improves detection of low-amplitude dopamine release	12
Dynamics of cerebral blood volume during and after middle cerebral artery occlusion in rats – Comparison between ultrafast ultrasound and dynamic susceptibility contrast-enhanced MRI measurements	12
Vitamin D deficiency promotes intracranial aneurysm rupture	11
Serotonergic regulation of cortical neurovascular coupling and hemodynamics upon awakening from sleep in mice	11
Manipulation of iron status on cerebral blood flow at high altitude in lowlanders and adapted highlanders	11
Long-term isoflurane anesthesia induces cognitive deficits via AQP4 depolarization mediated blunted glymphatic inflammatory proteins clearance	11
Autologous mitochondrial transplant for acute cerebral ischemia: Phase 1 trial results and review	11
Oral Abstracts	11
[18F]SF51, a novel 18F-labeled PET radioligand for translocator protein 18kDa (TSPO) in brain, works well in monkeys but fails in humans	11
Plasminogen activator inhibitor-1 mediates cerebral ischemia-induced astrocytic reactivity	11
Arterial specification precedes microvascular restitution in the peri-infarct cortex that is driven by small microvessels	11
Prediction of trends in unfavorable prognosis in patients with acute ischemic stroke according to low left ventricular ejection fraction levels	11
Serotonin 1B receptor density mapping of the human brainstem using positron emission tomography and autoradiography	11
Effect of drug interventions on cerebral hemodynamics in ischemic stroke patients	11
RAGE-mediated T cell metabolic reprogramming shapes T cell inflammatory response after stroke	11
Sporadic cerebral small vessel disease and cognitive decline in healthy older adults: A systematic review and meta-analysis	11