OOIR: Observatory of International Research

Papers

(The TQCC of Cellular and Molecular Neurobiology is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
In the Rat Midbrain, SG2NA and DJ-1 have Common Interactome, Including Mitochondrial Electron Transporters that are Comodulated Under Oxidative Stress	171
Altered Distribution of SNARE Proteins in Primary Neurons Exposed to Different Alpha-Synuclein Proteoforms	102
The Role of Non-coding RNAs in Methamphetamine-Induced Neurotoxicity	89
Cognitive Deficits Found in a Pro-inflammatory State are Independent of ERK1/2 Signaling in the Murine Brain Hippocampus Treated with Shiga Toxin 2 from Enterohemorrhagic Escherichia coli	71
A Tale of Two: When Neural Stem Cells Encounter Hypoxia	66
A Study on Autophagy Related Biomarkers in Alzheimer’s Disease Based on Bioinformatics	64
Analysis and Regulatory Mechanisms of Platelet-Related Genes in Patients with Ischemic Stroke	58
Dopamine Activates the D1R-Zn2+ Signaling Pathway to Trigger Inflammatory Response in Primary-Cultured Rat Embryonic Cortical Neurons	57
Amygdala Metabotropic Glutamate Receptor 1 Influences Synaptic Transmission to Participate in Fentanyl-Induced Hyperalgesia in Rats	56
Bone Marrow-Derived Mononuclear Cells in the Treatment of Neurological Diseases: Knowns and Unknowns	54
Correction to: The Neuroprotective Effects and Probable Mechanisms of Everolimus in a Rat Model of Intracerebral Hemorrhage	50
The Role of Cannabinoids in CNS Development: Focus on Proliferation and Cell Death	48
Molecular and Regenerative Characterization of Repair and Non-repair Schwann Cells	46
Cellular and Molecular Regulation of Exercise—A Neuronal Perspective	45
Mutation in the TRKB Cholesterol Recognition Site that blocks Antidepressant Binding does not Influence the Basal or BDNF-Stimulated Activation of TRKB	44
Can Environmental Enrichment Modulate Epigenetic Processes in the Central Nervous System Under Adverse Environmental Conditions? A Systematic Review	43
Discovery and Characterization of Ephrin B2 and EphB4 Dysregulation and Novel Mutations in Cerebral Cavernous Malformations: In Vitro and Patient-Derived Evidence of Ephrin-Mediated Endothelial Cell P	41
Expression Profile, Molecular Association, and Clinical Significance of POLD4 in Glioblastoma	41
Laser-Induced Axotomy of Human iPSC-Derived and Murine Primary Neurons Decreases Somatic Tau and AT8 Tau Phosphorylation: A Single-Cell Approach to Study Effects of Acute Axonal Damage	40
Drivers of Chronic Pathology Following Ischemic Stroke: A Descriptive Review	36
The Progress in Molecular Transport and Therapeutic Development in Human Blood–Brain Barrier Models in Neurological Disorders	36
Protein Biomarkers in Blood Reflect the Interrelationships Between Stroke Outcome, Inflammation, Coagulation, Adhesion, Senescence and Cancer	36
Melatonin and Health: Insights of Melatonin Action, Biological Functions, and Associated Disorders	35
Genetic Discrimination of Grade 3 and Grade 4 Gliomas by Artificial Neural Network	35
Clinical Insights on Caloric Restriction Mimetics for Mitigating Brain Aging and Related Neurodegeneration	34

Viruses and Mitochondrial Dysfunction in Neurodegeneration and Cognition: An Evolutionary Perspective	33
Fetal Brain Damage in Human Fetuses with Congenital Cytomegalovirus Infection: Histological Features and Viral Tropism	32
Klotho Upregulation via PPARγ Contributes to the Induction of Brain Ischemic Tolerance by Cerebral Ischemic Preconditioning in Rats	31
Correction: Proteomic and Cytokine Profiling in Plasma from Patients with Normal-Tension Glaucoma and Ocular Hypertension	31
Disease-Associated Neurotoxic Astrocyte Markers in Alzheimer Disease Based on Integrative Single-Nucleus RNA Sequencing	31
Inhibition of the Proteasome Regulator PA28 Aggravates Oxidized Protein Overload in the Diabetic Rat Brain	30
The Role of Retinal Dysfunction in Myopia Development	30
Tau Aggregation Inhibiting Peptides as Potential Therapeutics for Alzheimer Disease	30
Systematic Analysis of RNA Expression Profiles in Different Ischemic Cortices in MCAO Mice	29
Inhibition of UHRF1 Improves Motor Function in Mice with Spinal Cord Injury	29
AQP4 is an Emerging Regulator of Pathological Pain: A Narrative Review	28
Screening Plasma Proteins for the Putative Drug Targets for Carpal Tunnel Syndrome	28
Relevance of Thymic Stromal Lymphopoietin on the Pathogenesis of Glioblastoma: Role of the Neutrophil	26
Finding an Optimal Level of GDNF Overexpression: Insights from Dopamine Cycling	26
Lanthanum Chloride Induces Axon Abnormality Through LKB1-MARK2 and LKB1-STK25-GM130 Signaling Pathways	25
Research Progress on the Immune-Inflammatory Mechanisms of Posttraumatic Epilepsy	25
The Role of ERK1/2 Pathway in the Pathophysiology of Alzheimer’s Disease: An Overview and Update on New Developments	25
Pesticide Exposure and Its Association with Parkinson’s Disease: A Case–Control Analysis	24
Iron Deposition in Parkinson’s Disease: A Mini-Review	23
Bi-Directional Relationship Between Autophagy and Inflammasomes in Neurodegenerative Disorders	23
Proteomic and Cytokine Profiling in Plasma from Patients with Normal-Tension Glaucoma and Ocular Hypertension	22
Correction: Upregulation of Glutamatergic Receptors in Hippocampus and Locomotor Hyperactivity in Aged Spontaneous Hypertensive Rat	22
A Carboxy-terminal Smarcb1 Point Mutation Induces Hydrocephalus Formation and Affects AP-1 and Neuronal Signalling Pathways in Mice	22
The Provenance, Providence, and Position of Endothelial Cells in Injured Spinal Cord Vascular Pathology	21
Treadmill Running Regulates Adult Neurogenesis, Spatial and Non-spatial Learning, Parvalbumin Neuron Activity by ErbB4 Signaling	21
Primary Hypothyroidism and Alzheimer’s Disease: A Tale of Two	21
Dietary Fiber Modulates the Release of Gut Bacterial Products Preventing Cognitive Decline in an Alzheimer’s Mouse Model	20
Are mGluR2/3 Inhibitors Potential Compounds for Novel Antidepressants?	20
ACh Transfers: Homeostatic Plasticity of Cholinergic Synapses	19
FAM3A Ameliorates Brain Impairment Induced by Hypoxia–Ischemia in Neonatal Rat	19
Mesenchymal Stromal Cells-Derived Exosome and the Roles in the Treatment of Traumatic Brain Injury	19
Correction: Effect of Induction Time on the Proliferation and Differentiation of Induced Schwann‑Like Cells from Adipose‑Derived Stem Cells	19
Navigating the Landscape of MANF Research: A Scientometric Journey with CiteSpace Analysis	19
The Mechanisms of Ferroptosis Under Hypoxia	19
Prenatal Exposure to General Anesthesia Drug Esketamine Impaired Neurobehavior in Offspring	18
Pathophysiology, Diagnosis, Treatment, and Genetics of Carpal Tunnel Syndrome: A Review	18
The Role of Beta2-Microglobulin in Central Nervous System Disease	18
A Bibliometric Analysis of the Spatial Transcriptomics Literature from 2006 to 2023	18
REST in the Road Map of Brain Development	18
The Role of Inflammatory Cascade and Reactive Astrogliosis in Glial Scar Formation Post-spinal Cord Injury	18
Experiences Shape Hippocampal Neuron Morphology and the Local Levels of CRHR1 and OTR	17
Potential Prion Involvement in Long COVID-19 Neuropathology, Including Behavior	17
The Critical Role of RNA m6A Methylation in Gliomas: Targeting the Hallmarks of Cancer	17
Human Oral Mucosa Stem Cells Increase Survival of Neurons Affected by In Vitro Anoxia and Improve Recovery of Mice Affected by Stroke Through Time-limited Secretion of miR-514A-3p	17
Enlarged Perivascular Space and Index for Diffusivity Along the Perivascular Space as Emerging Neuroimaging Biomarkers of Neurological Diseases	17
Retraction Note: The Interplay of Tau Protein and β-Amyloid: While Tauopathy Spreads More Profoundly Than Amyloidopathy, Both Processes Are Almost Equally Pathogenic	17
Synergistic Epistasis and Systems Biology Approaches to Uncover a Pharmacogenomic Map Linked to Pain, Anti-Inflammatory and Immunomodulating Agents (PAIma) in a Healthy Cohort	16
Activation of TRPV1 Channels Inhibits the Release of Acetylcholine and Improves Muscle Contractility in Mice	16
Mechanism of Cone Degeneration in Retinitis Pigmentosa	16
Elabela, a Novel Peptide, Exerts Neuroprotective Effects Against Ischemic Stroke Through the APJ/miR-124-3p/CTDSP1/AKT Pathway	16

Neuromodulation Through Magnetic Fields Irradiation with AT-04 Improves Hyperalgesia in a Rat Model of Neuropathic Pain via Descending Pain Modulatory Systems and Opioid Analgesia	16
Neurological Consequences, Mental Health, Physical Care, and Appropriate Nutrition in Long-COVID-19	16
Identifying Candidate Genes Associated with Sporadic Amyotrophic Lateral Sclerosis via Integrative Analysis of Transcriptome-Wide Association Study and Messenger RNA Expression Profile	16
Role of Ferroptosis in Stroke	16
CircSKA3 is Associated With the Risk of Extracranial Artery Stenosis and Plaque Instability Among Ischemic Stroke Patients	15
Neuroepigenetic Changes in DNA Methylation Affecting Diabetes-Induced Cognitive Impairment	15
Uncovering the Significance of STEP61 in Alzheimer’s Disease: Structure, Substrates, and Interactome	15
Role of NAD+ and FAD in Ischemic Stroke Pathophysiology: An Epigenetic Nexus and Expanding Therapeutic Repertoire	15
Advanced Overview of Biomarkers and Techniques for Early Diagnosis of Alzheimer’s Disease	15
Hypoglycemia and Alzheimer Disease Risk: The Possible Role of Dasiglucagon	15
Urine Proteomic Signatures of Mild Hypothermia Treatment in Cerebral Ischemia–Reperfusion Injury in Rats	15
Trehalose–Carnosine Prevents the Effects of Spinal Cord Injury Through Regulating Acute Inflammation and Zinc(II) Ion Homeostasis	15
S-Ketamine Exerts Antidepressant Effects by Regulating Rac1 GTPase Mediated Synaptic Plasticity in the Hippocampus of Stressed Rats	15
Correction: Upregulation of miR-107 Inhibits Glioma Angiogenesis and VEGF Expression	15
Liquid Biopsy in Low-Grade Glioma: A Systematic Review and a Proposal for a Clinical Utility Score	15