OOIR: Observatory of International Research

Papers

(The median citation count of Seminars in Liver Disease is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Critical Care Management of Acute-on-Chronic Liver Failure: Certainties and Unknowns	70
Tight Junction Proteins as Therapeutic Targets to Treat Liver Fibrosis and Hepatocellular Carcinoma	35
Hepatic Extracellular Matrix and Its Role in the Regulation of Liver Phenotype	31
A Precision Medicine Guided Approach to the Utilization of Biomarkers in MASLD	29
Liver Immunology, Immunotherapy, and Liver Cancers: Time for a Rethink?	28
Tailored Model of Care for Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease	25
Genetic and Epigenetic Basis of Drug-Induced Liver Injury	24
Patient-Reported Outcomes in Metabolic Dysfunction-Associated Steatotic Liver Disease	22
HBV Biomarkers and Their Role in Guiding Treatment Decisions	21
Genetic Contributions to Biliary Atresia: A Developmental Cholangiopathy	20
Emerging Targets for the Treatment of Primary Sclerosing Cholangitis	18
Role of YAP1 Signaling in Biliary Development, Repair, and Disease	16
Mechanisms of Pharmacoresistance in Hepatocellular Carcinoma: New Drugs but Old Problems	15
Alcohol Plus Additional Risk Factors: Rodent Model of Liver Injury	15
Growth Hormone Signaling in Liver Diseases: Therapeutic Potentials and Controversies	13
Mice Engrafted with Human Liver Cells	13
Wilson Disease: Novel Diagnostic and Therapeutic Approaches	12
Dietary Recommendations for the Management of Non-alcoholic Fatty Liver Disease (NAFLD): A Nutritional Geometry Perspective	12
Physiomimetic In Vitro Human Models for Viral Infection in the Liver	12
A Global Systematic Review of Hepatitis C Elimination Efforts through Micro-Elimination	10
Diagnosis and Management of Early Stages of ALD	10
Primary Cilia in Hepatic Biliary Hyperplasia: Implications for Liver Diseases	10
Circadian Regulation of Gene Expression and Metabolism in the Liver	10
	10
Role of Intestinal Barrier Disruption to Acute-on-Chronic Liver Failure	9

Liver Neurobiology: Regulation of Liver Functions by the Nervous System	9
Role of Complement in Liver Diseases	9
This Is What Metabolic Dysfunction–Associated Steatotic Liver Disease Looks Like: Potential of a Multiparametric MRI Protocol	8
Liver Transplantation for Hepatocellular Carcinoma: A Narrative Review and A Glimpse into The Future	8
To TIPS or Not to TIPS in High Risk of Variceal Rebleeding and Acute-on-Chronic Liver Failure	8
	8
	7
Novel Biomarkers of AKI in Cirrhosis	7
Erratum to: Genetic Contributions to Biliary Atresia: A Developmental Cholangiopathy	7
The Hepatic Porphyrias: Revealing the Complexities of a Rare Disease	7
Management of Portal vein Thrombosis in Cirrhosis	7
Endoscopic Advances in Hepatology	7
Erratum to: Finite Antiviral Therapy in Chronic Hepatitis B Patients with Cirrhosis	7
Hepatocellular Carcinoma Chemoprevention with Generic Agents	7
Mesenchymal Stem Cell Transplantation in Liver Diseases	7
Pediatric and Adult Liver Disease in Alpha-1 Antitrypsin Deficiency	7
Hepatitis Delta Infection: A Clinical Review	7
Noninvasive Tests to Assess Fibrosis and Disease Severity in Metabolic Dysfunction-Associated Steatotic Liver Disease	6
LncRNAs, RNA Therapeutics, and Emerging Technologies in Liver Pathobiology	6
Is There a Safe Alcohol Consumption Limit for the General Population and in Patients with Liver Disease?	5
Extracellular Vesicles and Micro-RNAs in Liver Disease	5
Erratum to: Scavenger Receptors: Novel Roles in the Pathogenesis of Liver Inflammation and Cancer	5
Nonalcoholic Fatty Liver Disease: Current Global Burden	5
Advancements in MELD Score and Its Impact on Hepatology	5
Research Progress on the Role and Mechanism of IL-37 in Liver Diseases	5
Shared Mechanisms between Cardiovascular Disease and NAFLD	5
Scavenger Receptors: Novel Roles in the Pathogenesis of Liver Inflammation and Cancer	5
Screening for At-Risk Nonalcoholic Fatty Liver Disease in the Primary Care Setting	5
Metabolic Injury of Hepatocytes Promotes Progression of NAFLD and AALD	5
Big Data Analytics in Large Cohorts: Opportunities and Challenges for Research in Hepatology	5
	4
	4
Understanding Hepatic Porphyrias: Symptoms, Treatments, and Unmet Needs	4
The Ways to Die: Cell Death in Liver Pathophysiology	4
Gestational and Developmental Contributors of Pediatric MASLD	4
Unraveling the Complexities of Immune Checkpoint Inhibitors in Hepatocellular Carcinoma	4
Alcohol-Metabolizing Enzymes, Liver Diseases and Cancer	4
Influence of Sex in the Development of Liver Diseases	4
Hepatic Innervations and Nonalcoholic Fatty Liver Disease	4
	3
Role of Neutrophils in the Development of Steatotic Liver Disease	3
	3
Understanding and Treating Hepatorenal Syndrome: Insights from Recent Research	3
Role of Hepatocyte Nuclear Factor 4 Alpha in Liver Cancer	3
The Ploidy State as a Determinant of Hepatocyte Proliferation	3
Novel Endoscopic Bariatric Therapies for the Management of Nonalcoholic Steatohepatitis	3
Immune Checkpoint Inhibitor-Induced Liver Injury	3
Mastering Core Recommendations during HEPAtology ROUNDS in Patients with Advanced Chronic Liver Disease	3
Treating Alcohol Use Disorder in Patients with Alcohol-Associated Liver Disease: Controversies in Pharmacological Therapy	3
Pathogenesis and Management of Intestinal Failure-Associated Liver Disease	3

MetALD: Genetic Factors and Clinical Outcomes	2
Preface (Introduction): Metabolic Liver Disease: A New Era in Hepatology	2
UDCA for Drug-Induced Liver Disease: Clinical and Pathophysiological Basis	2
Early Diagnosis and Prevention of Infections in Cirrhosis	2
From a Single Cell to a Whole Human Liver: Disease Modeling and Transplantation	2
	2
Angiocrine Signaling in Sinusoidal Health and Disease	2
Inflammation in Steatotic Liver Diseases: Pathogenesis and Therapeutic Targets	2
Beyond Varices: Complications of Cirrhotic Portal Hypertension in Pediatrics	2
The Neglected Role of Bile Duct Epithelial Cells in NASH	2
Therapeutic Potential of Nutraceuticals against Drug-Induced Liver Injury	2
Current Challenges and Future Direction in Surveillance for Hepatocellular Carcinoma in Patients with Nonalcoholic Fatty Liver Disease	2
	2
NAFLD in Cardiovascular Diseases: A Contributor or Comorbidity?	2
	2
The Molecular Pathogenesis of Sarcopenia/Frailty in Cirrhosis	2