Regulatory Toxicology and Pharmacology

Papers
(The H4-Index of Regulatory Toxicology and Pharmacology is 28. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Perspectives on the elimination of animal assays in the assessment of carcinogenicity98
Target organ toxicity in Sprague Dawley rats following oral exposure to complex groundwater mixture: Assessment of dose-response relationships using histopathological and biochemical alterations74
Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats74
A Cautionary tale for using read-across for cancer hazard classification: Case study of isoeugenol and methyl eugenol72
Controlling cleaning agent residues in pharmaceutical manufacturing: A harmonized scientific strategy69
Prevalence and sample sizes in pre-clinical studies68
Ability of mathematical models to predict human in vivo percutaneous penetration of steroids63
Selectively addressing total risk avoidance for certain chemicals while overlooking others: The case of per-and-poly-fluoroalkyls57
Ames mutagenicity of 15 aryl, benzyl, and aliphatic ring N-nitrosamines57
Acceptable intakes (AIs) for 11 small molecule N-nitrosamines (NAs)52
Two-year carcinogenicity study of a novel plasticizer, bis(2-ethylhexyl) cyclohexane-1,4-dicarboxylate (Eco-DEHCH), by oral diet in Han Wistar rats52
Assessing biological oxidative damage induced by graphene-based materials: An asset for grouping approaches using the FRAS assay50
Preclinical safety evaluation of the ethanolic extract from the aerial parts of Gomphrena celosioides Mart. in rodents49
Is periventricular heterotopia a useful endpoint for developmental thyroid hormone system disruption in mouse toxicity studies?47
Control of N-nitrosamine impurities in drug products: Progressing the current CPCA framework and supporting the derivation of robust compound specific acceptable intakes45
Editorial Board44
Editorial Board42
Incorporating Singaporean habits and practices for cosmetics and personal care products into a global consumer aggregate exposure model41
Updated interim reference levels for dietary lead to support FDA's Closer to Zero action plan41
Results from two-year rodent oral carcinogenicity studies of cizolirtine, a substance-P and calcitonin gene-related peptide release modulator39
Acute dose toxicity evaluation of the food supplement calcium 3-hydroxy-3-methylbutyrate (HMB) in female Sprague Dawley rats36
Importance of tailored non-clinical safety testing of novel antimalarial drugs: Industry best-practice35
Apparent Khat chewers exposure to DDT in Ethiopia and its potential toxic effects: A scoping review33
False positive findings associated with adenoviral vector-based vaccine underscore the regulatory necessity to eliminate abnormal toxicity test32
Safety data sheets as an information pathway on hazards of occupationally used cleaning agents31
Decision making in next generation risk assessment for skin allergy: Using historical clinical experience to benchmark risk31
The SCCS Notes of Guidance for the testing of cosmetic ingredients and their safety evaluation, 11th revision, 30–31 March 2021, SCCS/1628/2129
Scientific considerations in the regulatory approval of generic (or biosimilar) version of enoxaparin sodium – A lifesaving carbohydrate polymer29
Nonclinical safety assessment of engineered T cell therapies28
The Dilemma of perfluorooctanoate (PFOA) human half-life28
Exploring the potential of ToxCast™ data for mechanism-based prioritization of chemicals in regulatory context: Case study with priority existing chemicals (PECs) under K-REACH28
Editorial: 2024 - A promising start for regulatory toxicology and pharmacology28
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