Regulatory Toxicology and Pharmacology

Papers
(The H4-Index of Regulatory Toxicology and Pharmacology is 28. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Perspectives on the elimination of animal assays in the assessment of carcinogenicity206
Evaluation of the OECD QSAR toolbox automatic workflow for the prediction of the acute toxicity of organic chemicals to fathead minnow87
Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats69
Ames mutagenicity of 15 aryl, benzyl, and aliphatic ring N-nitrosamines67
Target organ toxicity in Sprague Dawley rats following oral exposure to complex groundwater mixture: Assessment of dose-response relationships using histopathological and biochemical alterations63
Comprehensive investigation evaluating the carcinogenic hazard potential of acetaminophen62
Qualitative analysis of actual Standard for Exchange of Nonclinical Data (SEND) datasets for Data Domains: Proposition from Japan Pharmaceutical Manufacturers Association SEND Taskforce Team on standa62
Twenty six-week repeat dose oral rat toxicity study of cizolirtine, a substance-P and calcitonin gene-related peptide release modulator61
Controlling cleaning agent residues in pharmaceutical manufacturing: A harmonized scientific strategy50
Ability of mathematical models to predict human in vivo percutaneous penetration of steroids50
Selectively addressing total risk avoidance for certain chemicals while overlooking others: The case of per-and-poly-fluoroalkyls47
Two-year carcinogenicity study of a novel plasticizer, bis(2-ethylhexyl) cyclohexane-1,4-dicarboxylate (Eco-DEHCH), by oral diet in Han Wistar rats46
Preclinical safety evaluation of the ethanolic extract from the aerial parts of Gomphrena celosioides Mart. in rodents44
Assessing biological oxidative damage induced by graphene-based materials: An asset for grouping approaches using the FRAS assay42
Control of N-nitrosamine impurities in drug products: Progressing the current CPCA framework and supporting the derivation of robust compound specific acceptable intakes42
Acceptable intakes (AIs) for 11 small molecule N-nitrosamines (NAs)39
Editorial Board38
Is periventricular heterotopia a useful endpoint for developmental thyroid hormone system disruption in mouse toxicity studies?38
A Cautionary tale for using read-across for cancer hazard classification: Case study of isoeugenol and methyl eugenol38
Subchronic oral toxicity study of rhubarb extract in Sprague-Dawley rats37
Editorial Board37
Editorial: 2024 - A promising start for regulatory toxicology and pharmacology35
Incorporating Singaporean habits and practices for cosmetics and personal care products into a global consumer aggregate exposure model33
Results from two-year rodent oral carcinogenicity studies of cizolirtine, a substance-P and calcitonin gene-related peptide release modulator32
Acute dose toxicity evaluation of the food supplement calcium 3-hydroxy-3-methylbutyrate (HMB) in female Sprague Dawley rats31
Safety data sheets as an information pathway on hazards of occupationally used cleaning agents30
Importance of tailored non-clinical safety testing of novel antimalarial drugs: Industry best-practice29
Apparent Khat chewers exposure to DDT in Ethiopia and its potential toxic effects: A scoping review28
Scientific considerations in the regulatory approval of generic (or biosimilar) version of enoxaparin sodium – A lifesaving carbohydrate polymer28
False positive findings associated with adenoviral vector-based vaccine underscore the regulatory necessity to eliminate abnormal toxicity test28
Exploring the potential of ToxCastâ„¢ data for mechanism-based prioritization of chemicals in regulatory context: Case study with priority existing chemicals (PECs) under K-REACH28
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