OOIR: Observatory of International Research

Papers

(The TQCC of Pharmacotherapy is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Update and narrative review of avian influenza (H5N1) infection in adult patients	91
Characterization of lamotrigine disposition changes during and after pregnancy in women with epilepsy	88
	63
Assessment and management of iatrogenic withdrawal syndrome and delirium in pediatric intensive care units across Europe: An ESPNIC survey	52
Association of bleeding with serotonergic antidepressants in patients receiving left ventricular assist device support	50
Acid‐suppressive drugs: A systematic review and network meta‐analysis of their nocturnal acid‐inhibitory effect	42
Changes in serum potassium in people with type 2 diabetes taking sodium‐glucose co‐transporter‐2 inhibitors	38
Safety and efficacy of cefiderocol for off‐label treatment indications: A systematic review	37
Warfarin dosage in a postpartum woman while breastfeeding: A case report	36
Empiric dosing strategies to predict lamotrigine concentrations during pregnancy	34
Hydroxyurea treatment for sickle cell anemia during pregnancy and lactation: Current evidence and knowledge gaps	33
Comparison of risk‐scoring systems for heparin‐induced thrombocytopenia in cardiac surgery patients	33
Statin‐associated muscle symptoms—A review: Individualizing the approach to optimize care	30
Comparative safety and efficacy of bisphosphonates, denosumab, and parathyroid hormone analogs for osteoporosis following lung transplantation	29
	27
Impact of concurrent gabapentin or pregabalin with high‐dose melphalan in patients with multiple myeloma undergoing autologous hematopoietic stem cell transplant	27
Determination of vancomycin exposure target and individualized dosing recommendations for critically ill patients undergoing continuous renal replacement therapy	26
Patient safety outcomes for continuous infusion vancomycin as outpatient parenteral antimicrobial therapy	26
Biomarkers in the intensive care setting: A focus on using procalcitonin and C‐reactive protein to optimize antimicrobial duration of therapy	26
Optimal starting dosing regimen of intravenous oxytocin for labor induction based on the population kinetic‐pharmacodynamic model of uterine contraction frequency	26
Response to comment on “Dosing implications for liposomal amphotericin B in pregnancy”	25
Comment on “Evaluation of the safety and tolerability of intravenous undiluted levetiracetam at a pediatric institution”	25
Consensus recommendations for the use of novel antiretrovirals in persons with HIV who are heavily treatment‐experienced and/or have multidrug‐resistant HIV‐1: Endorse	24
Role of maternal COVID‐19 vaccination in providing immunological protection to the newborn	23
Reversal of apixaban and rivaroxaban with andexanet alfa prior to invasive or surgical procedures	23

Evaluation of the safety and tolerability of intravenous undiluted levetiracetam at a pediatric institution	23
Reduced risk of NSAID‐Induced adverse events with concomitant use of misoprostol (MICRO study)	21
	21
Oral fluoroquinolones and risk of aortic aneurysm or dissection: A nationwide population‐based propensity score‐matched cohort study	21
Issue Information	21
Pharmacotherapy research landscape and knowledge gaps of opioids in maternal and pediatric populations	19
Role of the gut microbiome in cardiovascular drug response: The potential for clinical application	19
Management of diffuse alveolar hemorrhage in the hematopoietic stem cell transplantation population: A systematic review	19
Effect of creatine monohydrate on motor function in children with facioscapulohumeral muscular dystrophy: A multicenter, randomized, double‐blind placebo‐controlled crossover trial	19
Effect of P2Y12 Inhibitors on Major Adverse Cardiovascular Events After Coronary Artery Bypass Graft Surgery: A Population‐Based Cohort Study	17
	17
Pharmacokinetic and pharmacodynamic evaluation of sulbactam‐durlobactam in a critically ill patient on continuous venovenous hemofiltration infected with carbapenem‐resistant Acinetobacter baumanni	16
Adverse Effects of Antidepressant Medications and their Management in Children and Adolescents	16
	16
Approaches to Precision‐based Anticoagulation management in the critically Ill	16
Cefazolin in the treatment of central nervous system infections: A narrative review and recommendation	16
Issue Information	16
Early combination therapy with immunoglobulin and steroids is associated with shorter ICU length of stay in Multisystem Inflammatory Syndrome in Children (MIS‐C) associated with	16
	16
Impact of dexmedetomidine in conjunction with a weaning protocol on post‐surgical opioid use in a neonatal intensive care unit	15
Issue Information	15
Issue Information	14
Proton pump inhibitor concomitant use to prevent oxaliplatin‐induced peripheral neuropathy: Clinical retrospective cohort study	14
Use of proton pump inhibitors and risk of severe COVID‐19: A case–control study in United States Medicare beneficiaries	14
	14
Current therapies and challenges for the treatment of Staphylococcus aureus biofilm‐related infections	14
Issue Information	14
Issue Information	14
Comment on “Intravenous ketamine successfully treats treatment‐resistant catatonia in schizophrenia: A case report”	14
Open‐source maximum a posteriori‐bayesian dosing AdDS to current therapeutic drug monitoring: Adapting to the era of individualized therapy	13
Efficacy and safety of factor Xa inhibitors in low body weight patients	13
Pain management considerations in patients living with both pain syndromes and cardiovascular diseases and disorders	13
Reply to Comment on: Tacrolimus in the treatment of childhood nephrotic syndrome: Machine learning detects novel biomarkers and predicts efficacy	13
Hydrocortisone versus vasopressin for the management of adult patients with septic shock refractory to norepinephrine: A multicenter retrospective study	13
Cardiovascular and kidney outcomes of spironolactone or eplerenone in combination with ACEI/ARBs in patients with diabetic kidney disease	13
Fluoroquinolones and the risk of aortic aneurysm or dissection: A population‐based propensity score‐matched German cohort study	12
Impact of concomitant fluconazole on direct oral anticoagulant bleeding risk	12
	12
A dose‐escalation clinical trial of intranasal ketamine for uncontrolled cancer‐related pain	12
Effects of statin therapy and treatment duration on cardiovascular disease risk in patients with nephrotic syndrome: A nested case–control study	11
A pharmacogenetic precision medicine approach to analgesia and sedation optimization in critically ill adults	11
Performance of different body weights in the Cockcroft‐Gault equation in critically ill patients with and without augmented renal clearance: A multicenter cohort	11
Scoping review of rational polytherapy in patients with drug‐resistant epilepsy	11
Risks of serious adverse events and kidney injury in patients treated with ibandronate: A systematic review and meta‐analysis	11
Critique of “Angiotensin‐converting enzyme inhibitors reduce community‐acquired pneumonia hospitalization and mortality”	11
Caring for two in the ICU: Pharmacologic management of pregnancy‐related complications	11
External evaluation of neonatal vancomycin population pharmacokinetic models: Moving from first‐order equations to Bayesian‐guided therapeutic monitoring	10
Issue Information	10
Impact of medication intensification on 30‐day hospital readmissions in a geriatric trauma population: A multicenter cohort study	10
Association between household opioid prescriptions and risk for overdose among family members not prescribed opioids	10

Standards of practice to advance the quality of health care	10
Comment on “The power and pitfalls of underpowered studies”	10
Update on the clinical applications of SGLTis: Insight to benefits beyond hypoglycemic and cardiorenal protection	10
Current clinical pharmacology issues in pregnancy and pediatrics	10
Issue Information	10
The role of inflammation in the pathogenesis and treatment of arrhythmias	10
Buprenorphine initiation strategies for opioid use disorder and pain management: A systematic review	10
Oral stepdown in Gram‐positive bloodstream infections: A step in the right direction	9
Response to comment on “Intravenous ketamine successfully treats treatment‐resistant catatonia in schizophrenia: A case report”	9
Effect of proton pump inhibitors versus histamine‐2 receptor antagonists on acute kidney injury in septic patients at high risk for developing stress ulcers	9
Impact of pre‐lung transplant statin use on the development of primary graft dysfunction	9
Myocardial infarction associated with erenumab: A case report	9
Emerging therapies for eosinophilic esophagitis	9
Serum potassium response to single‐dose sodium zirconium cyclosilicate for the treatment of asymptomatic hyperkalemia in hospitalized patients	9
Aztreonam–avibactam: The dynamic duo against multidrug‐resistant gram‐negative pathogens	9
Correction to “Comparative adherence trajectories of oral disease‐modifying agents in multiple sclerosis”	9
Metformin use is associated with reduced acute kidney injury following coronary artery bypass grafting in patients with type 2 diabetes: An inverse probability of treatment weighting analysis	9
Temporal shifts in safety and efficacy profile of mycophenolate mofetil 2 g versus 3 g daily early after heart transplantation	8
Cross‐titration from risperidone to clozapine utilizing clozapine serum concentrations: A case report	8
Issue Information	8
Pharmacokinetic parameters over time during sepsis and the association of target attainment and outcomes in critically ill children and young adults receiving ceftriaxone	8
Precision‐based approaches to delirium in critical illness: A narrative review	8
Evaluation of anti‐factor Xa concentrations using a body mass index‐based enoxaparin dosing protocol for venous thromboembolism prophylaxis in trauma patients	8
The efficacy and safety of sodium‐glucose cotransporter‐2 inhibitors in solid organ transplant recipients: A scoping review	8
Managing attention‐deficit/hyperactivity disorder in a breastfeeding mother: A case report	8
Comment on “Tacrolimus in the treatment of childhood nephrotic syndrome: Machine learning detects novel biomarkers and predicts efficacy”	7
“Comment on ‘international consensus recommendations for the use of prolonged‐infusion β‐lactams endorsed by the American College of Clinical Pharmacy (ACCP), the British Society for Antimi	7
Steno‐sphere: Navigating the enigmatic world of emerging multidrug‐resistantStenotrophomonas maltophilia	7
	7
Vancomycin: An analysis and evaluation of eight population pharmacokinetic models for clinical application in general adult population	7
Assessment of a modified MINDS‐based protocol for management of alcohol withdrawal syndrome on an inpatient medical service	7
Population pharmacokinetics of linezolid and its major metabolites PNU‐142300 and PNU‐142586 in adult patients	7
Evaluation of hyponatremia among older adults exposed to selective serotonin reuptake inhibitors and thiazide diuretics	7
	7
Cardiovascular adverse events in patients with hepatocellular carcinoma receiving vascular endothelial growth factor inhibitors	7
Use of naldemedine is associated with reduced incidence of hyperactive delirium in cancer patients with opioid‐induced constipation: A nationwide retrospective cohort study in Japan	7
Response to comment on “International consensus recommendations for the use of prolonged‐infusion β‐lactams endorsed by the American College of Clinical Pharmacy (ACCP), the British Society	7
The effect of antipsychotic treatment on hormonal, inflammatory, and metabolic biomarkers in healthy volunteers: A systematic review and meta‐analysis	7
TheMPRINTHub Data, Model, Knowledge and Research Coordination Center: Bridging the gap in maternal–pediatric therapeutics research through data integration and pharmacometrics	7
Tacrolimus in the treatment of childhood nephrotic syndrome: Machine learning detects novel biomarkers and predicts efficacy	7
Retrospective cohort study of oral switch versus intravenous antibiotics for carbapenem‐resistant enterobacterales and Pseudomonas aeruginosa infections on hospital discharge	6
Prevalence of prescription medication use that can exacerbate heart failure among US adults with heart failure	6
Beneficial and harmful outcomes of tocilizumab in severe COVID‐19: A systematic review and meta‐analysis	6
Expert consensus recommendations for innovative antiretroviral drugs	6
Issue Information	6
Simulated cost‐effectiveness of a novel precision‐guided dosing strategy in adult patients with Crohn's disease initiating infliximab maintenance therapy	6
Early clinical trial data and real‐world assessment of COVID‐19 vaccines: Insights from the Society of Infectious Diseases Pharmacists	6
Correction of posaconazole concentrations for hypoalbuminemia	6
Clinical outcomes associated with anti‐Xa‐monitored enoxaparin for venous thromboembolism prophylaxis	6
Pharmacokinetics/pharmacodynamics analysis and establishment of optimal dosing regimens using unbound cefmetazole concentration for patients infected with Extended‐Spectrum β‐lactamase prod	6
	6
	6
Impacts of age and BMI on vancomycin model choice in a Bayesian software: Lessons from a very large multi‐site retrospective study	6
Effect of cilostazol on preventing paclitaxel‐induced neuropathy in patients with breast cancer: A randomized controlled trial	6
Transfer of antibiotics and their metabolites in human milk: Implications for infant health and microbiota	6
Comparison of catheter‐related bloodstream infection rates in pediatric patients receiving parenteral nutrition with soybean oil‐based intravenous fat emulsion versus a mixed oil fat emulsion	6
Issue Information	6
	6
Increasing the bioavailability of oral esketamine by a single dose of cobicistat: A case study	6