OOIR: Observatory of International Research

Papers

(The TQCC of Pharmacotherapy is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Remdesivir: Review of Pharmacology, Pre‐clinical Data, and Emerging Clinical Experience for COVID‐19	188
Review of Emerging Pharmacotherapy for the Treatment of Coronavirus Disease 2019	153
Baricitinib: A Review of Pharmacology, Safety, and Emerging Clinical Experience in COVID‐19	141
COVID‐19 Clinical Diagnostics and Testing Technology	104
Therapeutic Potential for Tetracyclines in the Treatment of COVID‐19	88
Considerations for Statin Therapy in Patients with COVID‐19	78
Managing COVID‐19 in Renal Transplant Recipients: A Review of Recent Literature and Case Supporting Corticosteroid‐sparing Immunosuppression	67
Immunosuppression trends in solid organ transplantation: The future of individualization, monitoring, and management	63
A guide to therapeutic drug monitoring of β‐lactam antibiotics	62
Coagulopathy, Venous Thromboembolism, and Anticoagulation in Patients with COVID‐19	54
Vancomycin‐Induced Kidney Injury: Animal Models of Toxicodynamics, Mechanisms of Injury, Human Translation, and Potential Strategies for Prevention	48
Delayed Initiation of Remdesivir in a COVID‐19‐Positive Patient	48
Acetylcysteine for the Treatment of Suspected Remdesivir‐Associated Acute Liver Failure in COVID‐19: A Case Series	44
Consensus recommendations for use of maintenance immunosuppression in solid organ transplantation: Endorsed by the American College of Clinical Pharmacy, American Society of Transplantation, and the I	39
Tacrolimus intrapatient variability in solid organ transplantation: A multiorgan perspective	35
Adverse Effects of Antidepressant Medications and their Management in Children and Adolescents	31
Cefiderocol: A Novel Siderophore Cephalosporin against Multidrug‐Resistant Gram‐Negative Pathogens	29
Drug‐Induced Ototoxicity: A Comprehensive Review and Reference Guide	28
Meta‐analysis of clinical outcomes of PCSK9 modulators in patients with established ASCVD	27
An Overview of the Treatment of Less Common Non–Lactose‐Fermenting Gram‐Negative Bacteria	26
Approach to the Treatment of Patients with Serious Multidrug‐Resistant Pseudomonas aeruginosa Infections	25
Beneficial and harmful outcomes of tocilizumab in severe COVID‐19: A systematic review and meta‐analysis	25
Buprenorphine initiation strategies for opioid use disorder and pain management: A systematic review	24
Optimizing anticoagulation for patients receiving Impella support	24
Role of maternal COVID‐19 vaccination in providing immunological protection to the newborn	23

CYP2D6 Genetic Polymorphisms and Risperidone Pharmacokinetics: A Systematic Review and Meta‐analysis	23
Treatment of patients with serious infections due to carbapenem‐resistant Acinetobacter baumannii: How viable are the current options?	23
Comparison of high‐dose dual therapy with bismuth‐containing quadruple therapy in Helicobacter pylori‐infected treatment‐naive patients: An open‐label, multicenter, randomized controlled trial	23
Food effects on the formulation, dosing, and administration of cannabidiol (CBD) in humans: A systematic review of clinical studies	20
CBD and THC: Do They Complement Each Other Like Yin and Yang?	20
Analgesia and Sedation Strategies in Mechanically Ventilated Adults with COVID‐19	19
Effect of Preinjury Oral Anticoagulants on Outcomes Following Traumatic Brain Injury from Falls in Older Adults	19
Akathisia and Newer Second‐Generation Antipsychotic Drugs: A Review of Current Evidence	19
Systematic Review of Crizanlizumab: A New Parenteral Option to Reduce Vaso‐occlusive Pain Crises in Patients with Sickle Cell Disease	19
Combination of Vancomycin or Daptomycin and Beta‐lactam Antibiotics: A Meta‐analysis	18
Emerging therapies for the treatment of nonalcoholic steatohepatitis: A systematic review	18
Antibiotics in the Biliary Tract: A Review of the Pharmacokinetics and Clinical Outcomes of Antibiotics Penetrating the Bile and Gallbladder Wall	18
Systematic Review of Voxelotor: A First‐in‐Class Sickle Hemoglobin Polymerization Inhibitor for Management of Sickle Cell Disease	17
Gut microbiome health and dysbiosis: A clinical primer	17
Risk of Venous Thromboembolism Associated With Tofacitinib and Baricitinib: A Systematic Review and Indirect Meta‐Analysis	16
Scoping review of augmented renal clearance in critically ill pediatric patients	16
Use of oral tetracyclines in the treatment of adult outpatients with skin and skin structure infections: Focus on doxycycline, minocycline, and omadacycline	16
DPYD and UGT1A1 Pharmacogenetic Testing in Patients with Gastrointestinal Malignancies: An Overview of the Evidence and Considerations for Clinical Implementation	15
Systematic review and meta‐analysis of the correlation between bispectral index (BIS) and clinical sedation scales: Toward defining the role of BIS in critically ill patients	15
Association of proton pump inhibitor use with endothelial function and metabolites of the nitric oxide pathway: A cross‐sectional study	15
Cisplatin‐induced nephrotoxicity in an outpatient setting	15
Use of direct‐acting oral anticoagulants in solid organ transplantation: A systematic review	15
Therapeutic review of cabotegravir/rilpivirine long‐acting antiretroviral injectable and implementation considerations at an HIV specialty clinic	15
Potential Implications of Gut Microbiota in Drug Pharmacokinetics and Bioavailability	14
Physiologically based pharmacokinetic modeling of tramadol to inform dose adjustment and drug‐drug interactions according to CYP2D6 phenotypes	14
A systematic review of the drug–drug interaction between statins and colchicine: Patient characteristics, etiologies, and clinical management strategies	14
Long‐term Follow‐up of Hematopoietic Stem Cell Transplant Survivors: A Focus on Screening, Monitoring, and Therapeutics	14
Corticosteroid use in ARDS and its application to evolving therapeutics for coronavirus disease 2019 (COVID‐19): A systematic review	14
Race and sex associations with tacrolimus pharmacokinetics in stable kidney transplant recipients	13
Combining Antidepressants with β‐Blockers: Evidence of a Clinically Significant CYP2D6 Drug Interaction	13
Vancomycin area under the curve versus trough only guided dosing and the risk of acute kidney injury: Systematic review and meta‐analysis	13
Alopecia signals associated with calcitonin gene‐related peptide inhibitors in the treatment or prophylaxis of migraine: A pharmacovigilance study	12
Bamlanivimab use in mild‐to‐moderate COVID‐19 disease: A matched cohort design	12
Advances in CAR T Therapy for Hematologic Malignancies	12
Comparison of Bayesian‐derived and first‐order analytic equations for calculation of vancomycin area under the curve	12
Prophylactic norepinephrine infusion for postspinal anesthesia hypotension in patients undergoing cesarean section: A randomized, controlled, dose‐finding trial	12
The association between urate‐lowering therapies and treatment‐related adverse events, liver damage, and major adverse cardiovascular events (MACE): A network meta‐analysis of randomized trials	12
Use of psychiatric medication by college students: A decade of data	12
Evolving Therapeutic Options for Chronic Graft‐versus‐Host Disease	12
Tebipenem pivoxil hydrobromide—No PICC, no problem!	11
Glucagon: Its evolving role in the management of hypoglycemia	11
Multi‐center retrospective study evaluating the efficacy and safety of apixaban versus warfarin for treatment of venous thromboembolism in patients with severe obesity	11
Cardiovascular and kidney outcomes of spironolactone or eplerenone in combination with ACEI/ARBs in patients with diabetic kidney disease	11
Myocardial infarction associated with erenumab: A case report	11
Poor tolerability of cystic fibrosis transmembrane conductance regulator modulator therapy in lung transplant recipients	11
Prescription Medication Use in Older Adults Without Major Cardiovascular Disease Enrolled in the Aspirin in Reducing Events in the Elderly (ASPREE) Clinical Trial	11
The impact of statin use prior to intensive care unit admission on critically ill patients with sepsis	11
Achievement of goal anti‐Xa activity with weight‐based enoxaparin dosing for venous thromboembolism prophylaxis in trauma patients	10
Pneumococcal vaccination—A literature review and practice guideline update	10
Statin‐associated muscle symptoms—A review: Individualizing the approach to optimize care	10

Utility of triazole antifungal therapeutic drug monitoring: Insights from the Society of Infectious Diseases Pharmacists	10
Hydroxychloroquine in Hospitalized Patients with COVID‐19: Real‐World Experience Assessing Mortality	10
Current therapies and challenges for the treatment of Staphylococcus aureus biofilm‐related infections	10
Early combination therapy with immunoglobulin and steroids is associated with shorter ICU length of stay in Multisystem Inflammatory Syndrome in Children (MIS‐C) associated with	10
Reduced alternative insulin dosing in hyperkalemia: A meta‐analysis of effects on hypoglycemia and potassium reduction	10
Omega‐3 fatty acids for the prevention of atherosclerotic cardiovascular disease	10
Anticholinergic medication burden and cognitive function in participants of the ASPREE study	10
Optimization of Vancomycin Dosing Regimen in Cancer Patients using Pharmacokinetic/Pharmacodynamic Modeling	10
National Trends in Oral Antibiotic Prescribing in United States Physician Offices from 2009 to 2016	10
Consensus recommendations for use of maintenance immunosuppression in solid organ transplantation: Endorsed by the American College of Clinical Pharmacy, American Society of Transplantation, and Inter	9
Response to intravenous racemic ketamine after switch from intranasal (S)‐ketamine on symptoms of treatment‐resistant depression and post‐traumatic stress disorder in Veterans: A retrospective case se	9
Using l‐Carnitine as a Pharmacologic Probe of the Interpatient and Metabolic Variability of Sepsis	9
Methadone‐associated QT interval prolongation in patients undergoing maintenance therapy in an urban opioid treatment program	9
Systematic review of drug–drug interactions between rifamycins and anticoagulant and antiplatelet agents and considerations for management	9
Antimicrobial susceptibility testing: An updated primer for clinicians in the era of antimicrobial resistance: Insights from the Society of Infectious Diseases Pharmacists	9
Use of oral anticoagulants among individuals with cancer and atrial fibrillation in the United States, 2010–2016	9
Safety and effectiveness of NMDA receptor antagonists for depression: A multidisciplinary review	9
Cefazolin in the treatment of central nervous system infections: A narrative review and recommendation	9
A Systematic Review and Meta‐Analysis of Metolazone Compared to Chlorothiazide for Treatment of Acute Decompensated Heart Failure	8
Safety and efficacy of a platelet glycoprotein Ib inhibitor for patients with non‐ST segment elevation myocardial infarction: A phase Ib/IIa study	8
Sulbactam‐durlobactam: A novel β‐lactam‐β‐lactamase inhibitor combination targeting carbapenem‐resistant Acinetobacter baumannii infections	8
Systematic literature review of insulin dose adjustments when initiating hemodialysis or peritoneal dialysis	8
The role of inflammation in the pathogenesis and treatment of arrhythmias	8
A pragmatic assessment of proton pump inhibitors vs. histamine type 2 receptor antagonists on clinically important gastrointestinal bleeding and mortality when used for stress ulcer prophylaxis in the	8
Using Child‐Pugh Class to Optimize Voriconazole Dosage Regimens and Improve Safety in Patients with Liver Cirrhosis: Insights from a Population Pharmacokinetic Model‐based Analysis	8
Safety of elexacaftor/tezacaftor/ivacaftor dose reduction: Mechanistic exploration through physiologically based pharmacokinetic modeling and a clinical case series	8
Apixaban and rivaroxaban use for atrial fibrillation in patients with obesity and BMI ≥50 kg/m²	8
Immunosuppression considerations in simultaneous organ transplant	8
Optimizing ceftaroline dosing in critically ill patients undergoing continuous renal replacement therapy	8
TheMPRINTHub Data, Model, Knowledge and Research Coordination Center: Bridging the gap in maternal–pediatric therapeutics research through data integration and pharmacometrics	8
NR3C2 genotype is associated with response to spironolactone in diastolic heart failure patients from the Aldo‐DHF trial	8
Patient risk factors for opioid‐related adverse drug events in hospitalized patients: A systematic review	7
Low‐dose versus standard‐dose four‐factor prothrombin complex concentrate for factor‐Xa inhibitor reversal in spontaneous and traumatic intracranial hemorrhage	7
Population pharmacokinetic model‐guided optimization of intravenous voriconazole dosing regimens in critically ill patients with liver dysfunction	7
International consensus recommendations for the use of prolonged‐infusion beta‐lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy	7
Lack of drug interaction between levetiracetam and high‐dose methotrexate in patients with lymphoma	7
Differences in Predicted Warfarin Dosing Requirements Between Hmong and East Asians Using Genotype‐Based Dosing Algorithms	7
Pharmacogenetics of P2Y₁₂ receptor inhibitors	7
Treprostinil Attains Clinically Therapeutic Concentrations in Neonates with Pulmonary Hypertension on Extracorporeal Membrane Oxygenation Support	7
Factors influencing antibiotic duration in culture‐negative neonatal early‐onset sepsis	7
Molecular Adsorbent Recirculating System Therapy with Continuous Renal Replacement Therapy Enhanced Clearance of Piperacillin in a Pediatric Patient and Led to Failure to Attain Pharmacodynamic Target	7
Reversal of apixaban and rivaroxaban with andexanet alfa prior to invasive or surgical procedures	7
A retrospective analysis of bleeding risk with rivaroxaban, enoxaparin, and aspirin following total joint arthroplasty or revision	7
Successful prolonged treatment of a carbapenem‐resistant Acinetobacter baumannii hip infection with cefiderocol: A case report	7
Comparing newborn outcomes after prenatal exposure to individual antidepressants: A retrospective cohort study	7
Adequacy of cefepime concentrations in the early phase of critical illness: A case for precision pharmacotherapy	7
Advances in the treatment of transthyretin cardiac amyloidosis: Current and emerging therapies	6
Tacrolimus time in therapeutic range and long‐term outcomes in heart transplant recipients	6
Pharmacokinetics of Vancomycin in Critically Ill Patients Undergoing Sustained Low‐Efficiency Dialysis	6
Modeling Kinetic Glomerular Filtration Rate in Adults with Stable and Unstable Kidney Function: Vancomycin as the Motivating Example	6
Use of therapeutic drug monitoring to characterize cefepime‐related neurotoxicity	6
TT genotype of the MMP‐9‐1562C/T polymorphism may be a risk factor for thrombolytic therapy‐induced hemorrhagic complications after acute ischemic stroke	6
Enoxaparin versus unfractionated heparin for venous thromboembolism prophylaxis in renally impaired ICU patients	6
Machine learning to predict vasopressin responsiveness in patients with septic shock	6
Pharmacokinetics and safety of lefamulin after single intravenous dose administration in subjects with impaired‐hepatic function	6
Evaluation of dosing strategies and trough concentrations of vancomycin in patients undergoing continuous venovenous hemofiltration	6
Impact of Incremental Delays in Appropriate Therapy on the Outcomes of Hospitalized Adult Patients with Gram‐negative Bloodstream Infections: “Every day matters”	6
Advances in personalized medicine and noninvasive diagnostics in solid organ transplantation	6
Pharmacotherapy for durable left ventricular assist devices	6
Administration of rabies immunoglobulin: Improving evidence‐based guidance for wound infiltration	6
Safety and efficacy of cefiderocol for off‐label treatment indications: A systematic review	6
Melatonin Use in Hospitalized Children for Non‐Anesthetic Indications: A Systematic Review	6
First‐Dose Vancomycin Pharmacokinetics Versus Empiric Dosing on Area‐Under‐the‐Curve Target Attainment in Critically Ill Patients	6
Association of CYP2B6 genetic polymorphisms with bupropion and hydroxybupropion exposure: A systematic review and meta‐analysis	6
A systematic review of clozapine‐associated inflammation and related monitoring	6
Precision‐based approaches to delirium in critical illness: A narrative review	6
COVID‐19: The Uninvited Guest in the Intensive Care Unit — Implications for Pharmacotherapy	6
Restrictive resuscitation in patients with sepsis and mortality: A systematic review and meta‐analysis with trial sequential analysis	6
The safety of rapid infusion levetiracetam: A systematic review	6