OOIR: Observatory of International Research

Papers

(The TQCC of Pharmacotherapy is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
	80
Changes in serum potassium in people with type 2 diabetes taking sodium‐glucose co‐transporter‐2 inhibitors	79
Safety and efficacy of cefiderocol for off‐label treatment indications: A systematic review	61
Warfarin dosage in a postpartum woman while breastfeeding: A case report	46
Association of bleeding with serotonergic antidepressants in patients receiving left ventricular assist device support	44
Assessment and management of iatrogenic withdrawal syndrome and delirium in pediatric intensive care units across Europe: An ESPNIC survey	41
Hydroxyurea treatment for sickle cell anemia during pregnancy and lactation: Current evidence and knowledge gaps	40
Update and narrative review of avian influenza (H5N1) infection in adult patients	38
Comparison of risk‐scoring systems for heparin‐induced thrombocytopenia in cardiac surgery patients	33
Treatment of patients with serious infections due to carbapenem‐resistant Acinetobacter baumannii: How viable are the current options?	32
Acid‐suppressive drugs: A systematic review and network meta‐analysis of their nocturnal acid‐inhibitory effect	32
Empiric dosing strategies to predict lamotrigine concentrations during pregnancy	31
Characterization of lamotrigine disposition changes during and after pregnancy in women with epilepsy	30
	29
Role of maternal COVID‐19 vaccination in providing immunological protection to the newborn	26
Impact of concurrent gabapentin or pregabalin with high‐dose melphalan in patients with multiple myeloma undergoing autologous hematopoietic stem cell transplant	26
Reduced risk of NSAID‐Induced adverse events with concomitant use of misoprostol (MICRO study)	25
Statin‐associated muscle symptoms—A review: Individualizing the approach to optimize care	25
Impact of CYP3A5 phenotype on tacrolimus time in therapeutic range and clinical outcomes in pediatric renal and heart transplant recipients	25
Reversal of apixaban and rivaroxaban with andexanet alfa prior to invasive or surgical procedures	24
Evaluation of the safety and tolerability of intravenous undiluted levetiracetam at a pediatric institution	23
Optimal starting dosing regimen of intravenous oxytocin for labor induction based on the population kinetic‐pharmacodynamic model of uterine contraction frequency	22
Oral fluoroquinolones and risk of aortic aneurysm or dissection: A nationwide population‐based propensity score‐matched cohort study	21
Patient safety outcomes for continuous infusion vancomycin as outpatient parenteral antimicrobial therapy	21
Determination of vancomycin exposure target and individualized dosing recommendations for critically ill patients undergoing continuous renal replacement therapy	21

Biomarkers in the intensive care setting: A focus on using procalcitonin and C‐reactive protein to optimize antimicrobial duration of therapy	21
Comment on “Evaluation of the safety and tolerability of intravenous undiluted levetiracetam at a pediatric institution”	20
Response to comment on “Dosing implications for liposomal amphotericin B in pregnancy”	20
Elbasvir/grazoprevir administered for 12 weeks via percutaneous endoscopic gastrostomy tube achieves sustained virologic response: A case report and a review of the literature	20
Consensus recommendations for the use of novel antiretrovirals in persons with HIV who are heavily treatment‐experienced and/or have multidrug‐resistant HIV‐1: Endorse	20
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Issue Information	19
Management of diffuse alveolar hemorrhage in the hematopoietic stem cell transplantation population: A systematic review	18
Role of the gut microbiome in cardiovascular drug response: The potential for clinical application	18
Approaches to Precision‐based Anticoagulation management in the critically Ill	18
Issue Information	17
Pharmacotherapy research landscape and knowledge gaps of opioids in maternal and pediatric populations	16
Early combination therapy with immunoglobulin and steroids is associated with shorter ICU length of stay in Multisystem Inflammatory Syndrome in Children (MIS‐C) associated with	16
Pharmacokinetic and pharmacodynamic evaluation of sulbactam‐durlobactam in a critically ill patient on continuous venovenous hemofiltration infected with carbapenem‐resistant Acinetobacter baumanni	16
Cefazolin in the treatment of central nervous system infections: A narrative review and recommendation	16
Effect of creatine monohydrate on motor function in children with facioscapulohumeral muscular dystrophy: A multicenter, randomized, double‐blind placebo‐controlled crossover trial	16
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Issue Information	15
Issue Information	15
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Adverse Effects of Antidepressant Medications and their Management in Children and Adolescents	15
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Current therapies and challenges for the treatment of Staphylococcus aureus biofilm‐related infections	14
Impact of dexmedetomidine in conjunction with a weaning protocol on post‐surgical opioid use in a neonatal intensive care unit	14
Comment on “Intravenous ketamine successfully treats treatment‐resistant catatonia in schizophrenia: A case report”	14
Proton pump inhibitor concomitant use to prevent oxaliplatin‐induced peripheral neuropathy: Clinical retrospective cohort study	14
Issue Information	14
Use of proton pump inhibitors and risk of severe COVID‐19: A case–control study in United States Medicare beneficiaries	14
Issue Information	13
Hydrocortisone versus vasopressin for the management of adult patients with septic shock refractory to norepinephrine: A multicenter retrospective study	13
	13
Pain management considerations in patients living with both pain syndromes and cardiovascular diseases and disorders	13
Issue Information	13
A dose‐escalation clinical trial of intranasal ketamine for uncontrolled cancer‐related pain	12
	12
Efficacy and safety of factor Xa inhibitors in low body weight patients	12
Impact of concomitant fluconazole on direct oral anticoagulant bleeding risk	12
Open‐source maximum a posteriori‐bayesian dosing AdDS to current therapeutic drug monitoring: Adapting to the era of individualized therapy	12
Reply to Comment on: Tacrolimus in the treatment of childhood nephrotic syndrome: Machine learning detects novel biomarkers and predicts efficacy	12
Cardiovascular and kidney outcomes of spironolactone or eplerenone in combination with ACEI/ARBs in patients with diabetic kidney disease	12
Effects of statin therapy and treatment duration on cardiovascular disease risk in patients with nephrotic syndrome: A nested case–control study	11
Scoping review of rational polytherapy in patients with drug‐resistant epilepsy	11
Risks of serious adverse events and kidney injury in patients treated with ibandronate: A systematic review and meta‐analysis	11
Fluoroquinolones and the risk of aortic aneurysm or dissection: A population‐based propensity score‐matched German cohort study	11
Caring for two in the ICU: Pharmacologic management of pregnancy‐related complications	11
A pharmacogenetic precision medicine approach to analgesia and sedation optimization in critically ill adults	10
Issue Information	10
Performance of different body weights in the Cockcroft‐Gault equation in critically ill patients with and without augmented renal clearance: A multicenter cohort	10
Standards of practice to advance the quality of health care	10
External evaluation of neonatal vancomycin population pharmacokinetic models: Moving from first‐order equations to Bayesian‐guided therapeutic monitoring	10

The role of inflammation in the pathogenesis and treatment of arrhythmias	10
Critique of “Angiotensin‐converting enzyme inhibitors reduce community‐acquired pneumonia hospitalization and mortality”	10
Issue Information	10
Myocardial infarction associated with erenumab: A case report	9
Comment on “The power and pitfalls of underpowered studies”	9
Impact of medication intensification on 30‐day hospital readmissions in a geriatric trauma population: A multicenter cohort study	9
Correction to “Comparative adherence trajectories of oral disease‐modifying agents in multiple sclerosis”	9
Association between household opioid prescriptions and risk for overdose among family members not prescribed opioids	9
Update on the clinical applications of SGLTis: Insight to benefits beyond hypoglycemic and cardiorenal protection	9
Response to comment on “Intravenous ketamine successfully treats treatment‐resistant catatonia in schizophrenia: A case report”	9
Current clinical pharmacology issues in pregnancy and pediatrics	9
Buprenorphine initiation strategies for opioid use disorder and pain management: A systematic review	9
Impact of pre‐lung transplant statin use on the development of primary graft dysfunction	8
Pharmacokinetic parameters over time during sepsis and the association of target attainment and outcomes in critically ill children and young adults receiving ceftriaxone	8
Effect of proton pump inhibitors versus histamine‐2 receptor antagonists on acute kidney injury in septic patients at high risk for developing stress ulcers	8
Cross‐titration from risperidone to clozapine utilizing clozapine serum concentrations: A case report	8
Metformin use is associated with reduced acute kidney injury following coronary artery bypass grafting in patients with type 2 diabetes: An inverse probability of treatment weighting analysis	8
Aztreonam–avibactam: The dynamic duo against multidrug‐resistant gram‐negative pathogens	8
Temporal shifts in safety and efficacy profile of mycophenolate mofetil 2 g versus 3 g daily early after heart transplantation	8
Oral stepdown in Gram‐positive bloodstream infections: A step in the right direction	8
Precision‐based approaches to delirium in critical illness: A narrative review	8
The efficacy and safety of sodium‐glucose cotransporter‐2 inhibitors in solid organ transplant recipients: A scoping review	8
Evaluation of anti‐factor Xa concentrations using a body mass index‐based enoxaparin dosing protocol for venous thromboembolism prophylaxis in trauma patients	8
Serum potassium response to single‐dose sodium zirconium cyclosilicate for the treatment of asymptomatic hyperkalemia in hospitalized patients	8
Comment on “Tacrolimus in the treatment of childhood nephrotic syndrome: Machine learning detects novel biomarkers and predicts efficacy”	7
Steno‐sphere: Navigating the enigmatic world of emerging multidrug‐resistantStenotrophomonas maltophilia	7
Issue Information	7
Use of naldemedine is associated with reduced incidence of hyperactive delirium in cancer patients with opioid‐induced constipation: A nationwide retrospective cohort study in Japan	7
Response to comment on “International consensus recommendations for the use of prolonged‐infusion β‐lactams endorsed by the American College of Clinical Pharmacy (ACCP), the British Society	7
Vancomycin: An analysis and evaluation of eight population pharmacokinetic models for clinical application in general adult population	7
Evaluation of hyponatremia among older adults exposed to selective serotonin reuptake inhibitors and thiazide diuretics	7
Assessment of a modified MINDS‐based protocol for management of alcohol withdrawal syndrome on an inpatient medical service	7
“Comment on ‘international consensus recommendations for the use of prolonged‐infusion β‐lactams endorsed by the American College of Clinical Pharmacy (ACCP), the British Society for Antimi	7
Emerging therapies for eosinophilic esophagitis	7
Tacrolimus in the treatment of childhood nephrotic syndrome: Machine learning detects novel biomarkers and predicts efficacy	7
Effect of cilostazol on preventing paclitaxel‐induced neuropathy in patients with breast cancer: A randomized controlled trial	6
	6
Population pharmacokinetics of linezolid and its major metabolites PNU‐142300 and PNU‐142586 in adult patients	6
Cardiovascular adverse events in patients with hepatocellular carcinoma receiving vascular endothelial growth factor inhibitors	6
Transfer of antibiotics and their metabolites in human milk: Implications for infant health and microbiota	6
Expert consensus recommendations for innovative antiretroviral drugs	6
Issue Information	6
Correction of posaconazole concentrations for hypoalbuminemia	6
Clinical outcomes associated with anti‐Xa‐monitored enoxaparin for venous thromboembolism prophylaxis	6
	6
The effect of antipsychotic treatment on hormonal, inflammatory, and metabolic biomarkers in healthy volunteers: A systematic review and meta‐analysis	6
Prevalence of prescription medication use that can exacerbate heart failure among US adults with heart failure	6
Retrospective cohort study of oral switch versus intravenous antibiotics for carbapenem‐resistant enterobacterales and Pseudomonas aeruginosa infections on hospital discharge	6
	6
	6
	6
TheMPRINTHub Data, Model, Knowledge and Research Coordination Center: Bridging the gap in maternal–pediatric therapeutics research through data integration and pharmacometrics	6
Pharmacokinetics/pharmacodynamics analysis and establishment of optimal dosing regimens using unbound cefmetazole concentration for patients infected with Extended‐Spectrum β‐lactamase prod	6
Comparison of catheter‐related bloodstream infection rates in pediatric patients receiving parenteral nutrition with soybean oil‐based intravenous fat emulsion versus a mixed oil fat emulsion	6
Beneficial and harmful outcomes of tocilizumab in severe COVID‐19: A systematic review and meta‐analysis	6
Issue Information	6
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