Food and Chemical Toxicology

Article	Citations
RIFM fragrance ingredient safety assessment, acetaldehyde ethyl cis-3-hexenyl acetal, CAS Registry Number 28069-74-1	305
Ouabain inhibitor rostafuroxin attenuates dextromethorphan-induced manic potential	230
Gut-gonad crosstalk in mice exposed to a “chemical cocktail” combining metabolomics and microbial profile by amplicon sequencing	157
Kidney toxicity and transcriptome analyses of male ICR mice acutely exposed to the mushroom toxin α-amanitin	156
No-observed adverse effect levels of deoxynivalenol and aflatoxin B1 in combination induced immune inhibition and apoptosis in vivo and in vitro	145
NRF-2α and mitophagy underlie enhanced mitochondrial functions and biogenesis induced by T-2 toxin in GH3 cells	139
Sustained high expression of NRF2 inhibits cell apoptosis in arsenite-transformed human keratinocytes	134
Investigation and evaluation of gastrointestinal toxicity biomarkers in rats with different sites of gastrointestinal injury	132
Editorial Board	127
Corrigendum to “In vitro and in vivo antitumor effects of Peanut agglutinin through induction of apoptotic and autophagic cell death” [Food Chem. Toxicol. 2014 64 369-77]	126
Theaflavin alleviates cisplatin-induced nephrotoxicity: Targeting SIRT1/p53/FOXO3a/Nrf2 signaling and the NF-kB inflammatory cascade	122
Editorial Board	116
Microcystin-LR exposure interfered maintenance of colonic microenvironmental homeostasis in rat	109
Inhibition of human sulfotransferases (SULTs) by per- and polyfluoroalkyl substances (PFASs) and structure-activity relationship	108
Gallic, ellagic acids and their oral combined administration induce kidney, lung, and heart injury after acute exposure in Wistar rats	102
Deoxynivalenol exposure induces liver damage in mice: Inflammation and immune responses, oxidative stress, and protective effects of Lactobacillus rhamnosus GG	96
Rutin, a natural flavonoid glycoside, ameliorates zearalenone induced liver inflammation via inhibiting lipopolysaccharide gut leakage and NF-κB signaling pathway in mice	95
Tectorigenin ameliorated high-fat diet-induced nonalcoholic fatty liver disease through anti-inflammation and modulating gut microbiota in mice	94
Diisobutyl phthalate (DiBP)-induced male germ cell toxicity and its alleviation approach	92
Anti-inflammatory action of betulin and its potential as a dissociated glucocorticoid receptor modulator	90
RIFM fragrance ingredient safety assessment, o-(Methylthio)-phenol, CAS Registry Number 1073-29-6	87
RIFM fragrance ingredient safety assessment, cis-3-hexenyl isobutyrate, CAS Registry Number 41519-23-7	87
Editorial Board	85
RIFM fragrance ingredient safety assessment, dihydrocarvyl acetate, CAS Registry Number 20777-49-5	85
Update to RIFM fragrance ingredient safety assessment, 3-methylbutanal diethyl acetal, CAS Registry Number 3842-03-3	83

RIFM fragrance ingredient safety assessment, hex-3-enyl acetate, CAS Registry Number 1708-82-3	77
RIFM fragrance ingredient safety assessment, 5,8-methano-2H-1-benzopyran, 6(or 7)-ethylideneoctahydro-, [4aR,5S,8S,8aS(or 4aR,5R,8S,8aR)]-rel-, CAS Registry Number 943723-15-7	76
RIFM fragrance ingredient safety assessment, 11-tridecen-6-one, 8,12-dimethyl-, CAS Registry Number 68141-18-4	72
Wheat embryo globulin protects against acute alcohol-induced liver injury in mice	72
RIFM fragrance ingredient safety assessment, 3-buten-2-one, 4-(2,2,3-trimethyl-6-methylenecyclohexyl)-, CAS registry number 79-68-5	72
From food-to-human microplastics and nanoplastics exposure and health effects: A review on food, animal and human monitoring data	71
Preclinical toxicity evaluation of the novel anti-hypertensive compound KSD179019	71
Predicting chemicals’ toxicity pathway of female reproductive disorders using AOP7 and deep neural networks	67
Assessing the toxic dose of the potent antioxidant 3,5-dihydroxy-4-methoxybenzyl alcohol in rats	67
The role of GSK3β signaling mediated lysosomal biosynthesis dysregulation in fluoride-induced neurological impairment	67
Sinomenine synergistically enhances 5-Fu anticancer effects in oral cancer through modulating the miR-140-5p-PDK1-anaerobic glycolysis pathway	65
Combined environmental relevant exposure to perfluorooctanoic acid and zinc sulfate enhances apoptosis through binding with endogenous antioxidants in Daphnia magna	63
Identification of non-volatile non-intentionally added substances from polyester food contact coatings and genotoxicity assessment of polyester coating's migrates	63
Silk fibroin peptide self-assembled nanofibers delivered naringenin to alleviate cisplatin-induced acute kidney injury by inhibiting mtDNA-cGAS-STING pathway	60
Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice	59
EGCG exposure during pregnancy affects uterine histomorphology in F1 female mice and the underlying mechanisms	59
Low-dose benzo[a]pyrene exposure induces hepatic lipid deposition through LCMT1/PP2Ac-mediated autophagy inhibition	57
Assessment of human health risk concerning edible plants contamination with toxic elements around functional and derelict mines	57
Gene expression profiles related to apoptosis and levels of DNA oxidative damage in primary dermal fibroblast cells (ATCC® PCS-201-012TM) treated with zirconium oxide nanoparticles	56
RIFM fragrance ingredient safety assessment, 2-methylpropyl 2-methylbutyrate, CAS Registry Number 2445-67-2	52
RIFM fragrance ingredient safety assessment, ethyl 2-ethylhexanoate, CAS Registry Number 2983-37-1	52
RIFM fragrance ingredient safety assessment, 2-pentylcyclopentan-1-ol, CAS Registry Number 84560-00-9	52
Update to RIFM fragrance ingredient safety assessment, 1-naphthalenol, 1,2,3,4,4a,5,8,8a-octahydro-2,2,6,8-tetramethyl-, CAS Registry Number 103614-86-4	51
RIFM fragrance ingredient safety assessment, 1-heptanethiol, CAS Registry Number 1639-09-4	50
RIFM fragrance ingredient safety assessment, bicyclo[2.2.1]heptan-2-ol, 1,3,3-trimethyl-, benzoate, CAS Registry Number 55066-54-1	50
RIFM fragrance ingredient safety assessment, S-(1-methylpropyl) 3-methylbut-2-enethioate, CAS Registry Number 34322-09-3	50
The potential developmental neurotoxicity of calcium cyclamate in CD rats	50
Update to RIFM fragrance ingredient safety assessment, 2H-inden-2-one, 1,3-dihydro-, CAS Registry Number 615-13-4	49
RIFM fragrance ingredient safety assessment, ethyl valerate, CAS Registry Number 539-82-2	49
Update to RIFM fragrance ingredient safety assessment, 4-methylpentanoic acid, CAS Registry Number 646-07-1	49
RIFM fragrance ingredient safety assessment, 2-acetyl-3-methylpyrazine, CAS Registry number 23787-80-6	49
Update to RIFM fragrance ingredient safety assessment, pentyl benzoate, CAS Registry Number 2049-96-9	48
RIFM natural complex substance (NCS) fragrance ingredient safety assessment, lavandin abrialis, CAS registry number 8022-15-9, RIFM ID 1048554	47
Cardiac oxylipin perturbances in response to 2-monochloropropane-1,3-diol exposure are ameliorated by dietary adequacy of the essential n-3 fatty acid, α-linolenic acid	46
RIFM fragrance ingredient safety assessment, furfural, CAS Registry Number 98-01-1	46
Update to RIFM fragrance ingredient safety assessment, octyl butyrate, CAS Registry Number 110-39-4	46
RIFM fragrance ingredient safety assessment, 5-hydroxy-4-methylhexanoic acid δ-lactone, CAS Registry Number 10413-18-0	46
RIFM fragrance ingredient safety assessment, α-amylcinnamaldehyde dimethyl acetal, CAS Registry Number 91-87-2	44
RIFM fragrance ingredient safety assessment, styrene, CAS Registry Number 100-42-5	43
Update to RIFM fragrance ingredient safety assessment, hexyl isovalerate, CAS Registry Number 10032-13-0	43
RIFM fragrance ingredient safety assessment, ethyl decanoate, CAS Registry Number 110-38-3	43
Green synthesized colloidal silver is devoid of toxic effects on primary human nasal epithelial cells in vitro	43
RIFM fragrance ingredient safety assessment, methyl butyrate, CAS registry number 623-42-7	42
RIFM fragrance ingredient safety assessment, isopentyl 2-methylcrotonate (E), CAS Registry Number 41519-18-0	42
Curcumin mitigates gentamicin induced-renal and cardiac toxicity via modulation of Keap1/Nrf2, NF-κB/iNOS and Bcl-2/BAX pathways	42
RIFM fragrance ingredient safety assessment, isoeugenyl methyl ether, CAS Registry Number 93-16-3	42
Neurotoxic effect of nalufin on the histology, ultrastructure, cell cycle and apoptosis of the developing chick embryo and its amelioration by selenium	41
Ellagitannins from jabuticaba (Myrciaria jaboticaba) seeds attenuated inflammation, oxidative stress, aberrant crypt foci, and modulated gut microbiota in rats with 1,2 dimethyl hydrazine-induced colo	41
Probiotic lactobacilli attenuate oxysterols-induced alteration of intestinal epithelial cell monolayer permeability: Focus on tight junction modulation	41
The “steric-like” inhibitory effect and mechanism of doxycycline on florfenicol metabolism: Interaction risk	40

MiR-93 alleviates DEHP plasticizer-induced neurotoxicity by negatively regulating TNFAIP1 and inhibiting ubiquitin-mediated degradation of CK2β	40
Bisphenol A and its analogue bisphenol S exposure reduce estradiol synthesis via the ROS-mediated PERK/ATF4 signaling pathway	40
Inhalation toxicity of thermal transformation products formed from e-cigarette vehicle liquid using an in vitro lung model exposed at the Air–Liquid Interface	40
Acrylamide in food: Occurrence, metabolism, molecular toxicity mechanism and detoxification by phytochemicals	39
Evaluation of cigarette smoke-induced oxidative stress and inflammation in BEAS-2B cells based on a lung microfluidic chip	39
Global review, meta-analysis and health risk assessment of Polycyclic Aromatic Hydrocarbons (PAHs) in chicken kebab using Monte Carlo simulation method	39
Toxicity assessment of heavy metals translocation in maize grown in the Ganges delta floodplain soils around the Payra power plant in Bangladesh	38
RIFM fragrance ingredient safety assessment, 3-mercaptohexyl acetate, CAS Registry Number 136954-20-6	38
Multivariate analysis of potentially toxic metal contents in soil and vegetables: Enrichment, bioconcentration, translocation from soil to vegetables, and assessment of human health toxicity	38
High throughput screening of bisphenols and their mixtures under conditions of low-intensity adipogenesis of human mesenchymal stem cells (hMSCs)	38
Farnesol prevents chlorpyrifos nephrotoxicity by modulating inflammatory mediators, Nrf2 and FXR and attenuating oxidative stress	38
Glutamate - A multifaceted molecule: Endogenous neurotransmitter, controversial food additive, design compound for anti-cancer drugs. A critical appraisal	38
Mitigating Bisphenol-Induced Neurotoxicity: Exploring the Therapeutic Potential of Diosmin in Zebrafish Larvae	38
Mycotoxins in raw materials, beverages and supplements of botanicals: A review of occurrence, risk assessment and analytical methodologies	37
GPx-1-encoded adenoviral vector attenuates dopaminergic impairments induced by methamphetamine in GPx-1 knockout mice through modulation of NF-κB transcription factor	37
Characterizing the risk related to the exposure to methylmercury over a lifetime: A global approach using population internal exposure	37
Rapid identification of counterfeited beef using deep learning-aided spectroscopy: Detecting colourant and curing agent adulteration	36
Immunoproteasome subunit PSMB8 regulates microglia-mediated neuroinflammation upon manganese exposure by PERK signaling	36
RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, tangelo oil, expressed, CAS Registry Number 72869-73-9, RIFM ID 931-G2.5	36
RIFM fragrance ingredient safety assessment, ethyl butyrate, CAS registry number 105-54-4	36
Update to RIFM fragrance ingredient safety assessment, methyl phenylacetate, CAS Registry Number 101-41-7	36
RIFM fragrance ingredient safety assessment, o-methoxybenzaldehyde, CAS Registry Number 135-02-4	35
RIFM fragrance ingredient safety assessment, ω-6-hexadecenlactone, CAS Registry Number 7779-50-2	35
RIFM fragrance ingredient safety assessment, patchouli alcohol, CAS Registry Number 5986-55-0	35
Update to RIFM fragrance ingredient safety assessment, trans-2-hexenoic acid, CAS Registry Number 13419-69-7	35
RIFM fragrance ingredient safety assessment, benzene, 1-(dimethoxymethyl)-4-methoxy-, CAS Registry Number 2186-92-7	34
Update to RIFM fragrance ingredient safety assessment, menthyl acetate (isomer unspecified), CAS registry number 16409-45-3	34
Update to RIFM fragrance ingredient safety assessment, ethyl benzoate, CAS Registry Number 93-89-0	34
RIFM fragrance ingredient safety assessment, dodecahydro-3,8,8,11a-tetramethyl-5H-3,5a-epoxynaphth[2,1-c]oxepin, CAS Registry Number 57345-19-4	33
RIFM fragrance ingredient safety assessment, p-isopropyl phenylacetaldehyde, CAS Registry Number 4395-92-0	33
RIFM fragrance ingredient safety assessment, germacrene D, CAS Registry Number 23986-74-5	33
Update to RIFM fragrance ingredient safety assessment, methyl benzoate, CAS Registry Number 93-58-3	33
Update to RIFM fragrance ingredient safety assessment, linalyl acetate, CAS registry number 115-95-7	32
Update to RIFM fragrance ingredient safety assessment, p-tolyl alcohol, CAS Registry Number 589-18-4	32
RIFM fragrance ingredient safety assessment, 3-(p-isopropylphenyl)propionaldehyde, CAS registry number 7775-00-0	32
RIFM fragrance ingredient safety assessment, phenethyl propionate, CAS Registry Number 122-70-3	31
RIFM fragrance ingredient safety assessment, cis- and trans-p-1(7),8-menthadien-2-yl acetate, CAS registry number 71660-03-2	31
RIFM fragrance ingredient safety assessment, pinocarvyl acetate, CAS Registry Number 1078-95-1	31
RIFM fragrance ingredient safety assessment, 3-phenyl-3-buten-1-yl acetate, CAS Registry Number 7306-12-9	31
RIFM fragrance ingredient safety assessment, d,l-menthone 1,2-glycerol ketal, CAS Registry Number 63187-91-7	31
Melatonin protects against diclofenac induced oxidative stress mediated myocardial toxicity in rats: A mechanistic insight	31
Isochlorogenic acid A ameliorated lead-induced anxiety-like behaviors in mice by inhibiting ferroptosis-mediated neuroinflammation via the BDNF/Nrf2/GPX4 pathways	31
RIFM fragrance ingredient safety assessment, 2-methyldecanenitrile, CAS Registry Number 69300-15-8	31
RIFM fragrance ingredient safety assessment, cycloionone, CAS Registry Number 5552-30-7	30
Epigallocatechin gallate-rich fraction alleviates histamine-induced neurotoxicity in rats via inactivating caspase-3/JNK signaling pathways	30
RIFM fragrance ingredient safety assessment, 2-phenylhexanenitrile, CAS registry number 3508-98-3	30
RIFM fragrance ingredient safety assessment, 1,1-dimethyl-2-phenylethyl acetate, CAS registry number 151-05-3	30
RIFM fragrance ingredient safety assessment, 6-methyl-5-hepten-2-one, CAS registry number 110-93-0	30
RIFM fragrance ingredient safety assessment, oxacyclopentadec-10-en-2-one, 13-methyl-, CAS Registry Number 329925-33-9	30
Update to RIFM fragrance ingredient safety assessment, nonyl acetate, CAS registry number 143-13-5	30
RIFM fragrance ingredient safety assessment, 2-ethylhexanal, CAS Registry Number 123-05-7	29
RIFM fragrance ingredient safety assessment, 2,4,4,7-tetramethylnona-6,8-diene-3-one-oxime, CAS Registry Number 81783-01-9	29
RIFM fragrance ingredient safety assessment, bisabolene, CAS registry number 495-62-5	29
RIFM fragrance ingredient safety assessment, 4-methoxy-α-methylbenzenepropanal, CAS Registry Number 5462-06-6	29
RIFM fragrance ingredient safety assessment, 1-formyl-1-methyl-4-(4-methyl-pentyl)-3-cyclohexene, CAS Registry Number 66327-54-6	29
RIFM fragrance ingredient safety assessment, 2-trans-6-cis-dodecadienal, CAS Registry Number 21662-13-5	29
Fertility-enhancing effects of inositol & vitamin C on cisplatin induced ovarian and uterine toxicity in rats via suppressing oxidative stress and apoptosis	28
Strategies to reduce sodium levels in European seabass sausages	28
Impact of food matrices on the characteristics and cellular toxicities of ingested nanoplastics in a simulated digestive tract	28
Corrigendum to “Rice bran extract mitigates depressive-like behavior in dextran sulfate sodium-induced colitis: Involvement of the gut-brain axis and Sirt1 signaling pathway” [Food and Chemical Toxico	28
CDKN1A promotes Cis-induced AKI by inducing cytoplasmic ROS production and ferroptosis	28
Bisphenol S exposure induces cytotoxicity in mouse Leydig cells	28
N-(2-ozoazepan-3-yl)-pyrrolidine-2-carboxamide, a novel Octopus vulgaris ink-derived metabolite, exhibits a pro-apoptotic effect on A549 cancer cell line and inhibits pro-inflammatory markers	28
Environmental toxicity risk evaluation of nitroaromatic compounds: Machine learning driven binary/multiple classification and design of safe alternatives	28
Update to RIFM fragrance ingredient safety assessment, α,2,2,3-tetramethylcyclopent-3-ene-1-butyraldehyde, CAS Registry Number 65114-03-6	28
RIFM fragrance ingredient safety assessment, 4-acetoxy-2,5-dimethyl-3(2H)furanone, CAS Registry Number 4166-20-5	28
Triptolide exposure triggers ovarian inflammation by activating cGAS-STING pathway and decrease oocyte quality in mouse	28
RIFM fragrance ingredient safety assessment, cedryl formate, CAS Registry Number 39900-38-4	27
Editorial Board	27
In silico and in vitro safety assessment of a fungal biomass from Rhizomucor pusillus for use as a novel food ingredient	27
Toxicology of Dyes: Editorial Introduction	27
RIFM fragrance ingredient safety assessment, (1aα,4α,7aα)-1a,3,3,4,6,6-hexamethyl-1a,2,3,4,5,6,7,7a-octahydronapth[3,3-b]oxirene, CAS Registry Number 94400-98-3	27
Corrigendum to “Effects of gelatin-based antifreeze peptides on cell viability and oxidant stress of Streptococcus thermophilus during cold stage” [Food Chem. Toxicol. 136 (2020) 111056]	27
RIFM fragrance ingredient safety assessment, acetylcarene, CAS Registry Number 3608-11-5	27
Comparison of the toxicity of pure compounds and commercial formulations of imidacloprid and acetamiprid on HT-29 cells: Single and mixture exposure	26
Unravelling the anti-inflammatory and antioxidant effects of standardized green and black caffeinated coffee, tea, and their mixtures in an obese male rat model: Insights from biochemical, metabolomic	26
RIFM fragrance ingredient safety assessment, sssmenthadiene-7-methyl formate, CAS registry number 68683-20-5	26
RIFM fragrance ingredient safety assessment,1-(2,2,6-trimethylcyclohexyl)-3-hexanol, CAS Registry Number 70788-30-6	26
Chlorinated organophosphorus flame retardants-induced mitochondrial abnormalities and the correlation with progesterone production in mLTC-1 cells	26
RIFM fragrance ingredient safety assessment, p-mentha-1,3-diene, CAS Registry Number 99-86-5	26

Editorial Board	26
Enniatin B and beauvericin affect intestinal cell function and hematological processes in Atlantic salmon (Salmo salar) after acute exposure	26
RIFM fragrance ingredient safety assessment, 3-methyl-2-butenyl salicylate, CAS Registry Number 68555-58-8	26
Pithecellobium dulce induces apoptosis and reduce tumor burden in experimental animals via regulating pro-inflammatory cytokines and anti-apoptotic gene expression	25
Bisphenol a exposure decreases learning ability through the suppression of mitochondrial oxidative phosphorylation in the hippocampus of male mice	25
Alcohol induces hepatocytes necroptosis through the LC3/RIPK1/RIPK3 pathway	25
Emamectin benzoate-induced toxicity affects intestinal epithelial integrity involving apoptosis	25
An integrated strategy combining network toxicology and feature-based molecular networking for exploring hepatotoxic constituents and mechanism of Epimedii Folium-induced hepatotoxicity in vitro	25
Piceatannol upregulates USP14-mediated GPX4 deubiquitination to inhibit neuronal ferroptosis caused by cerebral ischemia-reperfusion in mice	25
Deoxynivalenol upregulates hypoxia-inducible factor-1α to promote an “immune evasion” process by activating STAT3 signaling	25
Update to RIFM fragrance ingredient safety assessment, isobutyl propionate, CAS Registry Number 540-42-1	25
Development and application of an interactive generic physiologically based pharmacokinetic (igPBPK) model for adult beef cattle and lactating dairy cows to estimate tissue distribution and edible tis	25
In response to the Letter to the Editor from Xiao regarding our article, “FEMA GRAS assessment of natural flavor complexes: Asafetida oil, garlic oil and onion oil”	25
Liensinine, a alkaloid from lotus plumule, mitigates lipopolysaccharide-induced sepsis-associated encephalopathy through modulation of nuclear factor erythroid 2-related factor-mediated inflammatory b	25
Weighted analysis of 2′-fucosyllactose, 3-fucosyllactose, lacto-N-tetraose, 3′-sialyllactose, and 6′-sialyllactose concentrations in human milk	25
The key role of autophagy in silver nanoparticle-induced BV2 cells inflammation and polarization	25
Nutraceutical intervention protects against bacterial and chemical-induced gastrotoxicity in a non-mammalian model, Galleria mellonella	25
Organophosphate esters and their metabolites in Beijing total diets: Occurrence, time trend, and dietary exposure assessment	25
Role of MRPs transporters in pharmacokinetics and intestinal toxicity of irinotecan	25
Hyoscyamine induces developmental toxicity by disrupting metabolism in zebrafish embryo (Danio rerio)	25
Apigenin in cancer therapy: From mechanism of action to nano-therapeutic agent	25
Hyperoside attenuates Cd-induced kidney injury via inhibiting NLRP3 inflammasome activation and ROS/MAPK/NF-κB signaling pathway in vivo and in vitro	25
Association between Di-2-ethylhexyl phthalate and nonalcoholic fatty liver disease among US adults: Mediation analysis of body mass index and waist circumference in the NHANES	25
The current understanding of the benefits, safety, and regulation of cannabidiol in consumer products	25
Genetic variations of CYP3A4 on the metabolism of itraconazole in vitro	24
Dietary exposure to mixtures of chemicals in the first year of life and allergic and respiratory diseases up to 8 years in the French EDEN mother-child cohort	24
Chronic glucocorticoid exposure accelerates Aβ generation and neurotoxicity by activating calcium-mediated CN-NFAT1 signaling in hippocampal neurons in APP/PS1 mice	24
Imatinib disturbs lysosomal function and morphology and impairs the activity of mTORC1 in human hepatocyte cell lines	24
Lanthanum decreased VAPB-PTPP51, BAP31-FIS1, and MFN2-MFN1 expression of mitochondria-associated membranes and induced abnormal autophagy in rat hippocampus	24
Neurotoxicity of dibutyl phthalate in zebrafish larvae: Decreased energy acquisition by neurons	24
Therapeutic potential of 2S-hesperidin against the hepatotoxic effects of dichlorvos in rats	24
Endocrine disruptor hexachlorobenzene induces cell migration and invasion, and enhances aromatase expression levels in human endometrial stromal cells	24
Mitochondrial damage precedes the changes of glutathione metabolism in CdCl2 treated neuronal SH-SY5Y cells	24
Probiotic cultures as a potential protective strategy against the toxicity of environmentally relevant chemicals: State-of-the-art knowledge	24
The toxicity of lead on human neuroblastoma cells was alleviated by HUC-MSC-derived exosomes through miR-26a-5p/PTEN pathway	24
Sub-acute administration of metal-organic Framework-5 induces behavioral impairments and augments the levels of oxidative stress and inflammation in the brain of rats	24
Update to RIFM fragrance ingredient safety assessment, benzyl formate, CAS Registry Number 104-57-4	24
Safety and toxicologic evaluation of Edible Pongamia Oil: A novel food ingredient	24
Vallaris solanacea induces mitochondrial mediated apoptosis in HL-60 human promyelocytic leukemia cells	23
Potential exacerbation of polycystic ovary syndrome by saccharin sodium Via taste receptors in a letrozole rat model	23
RIFM fragrance ingredient safety assessment, 1-propanol, 2-methyl-3-[(1,7,7-trimethylbicyclo-[2.2.1]hept-2-yl)oxy]-, CAS Registry Number 128119-70-0	23
An in vitro protocol to characterise the resistance of food proteins to intestinal digestion	23
RIFM fragrance ingredient safety assessment, thymol, CAS Registry Number 89-83-8	23
High fructose-induced skeletal muscle insulin resistance could be alleviated by berberine via AMPD1 and ADSL	23
Bioactive extract of Morchella esculenta ameliorates cyclophosphamide-induced mitochondrial dysfunction and cardiotoxicity by modulating KEAP1/NRF2 and pro-inflammatory genes expression	23
Update to RIFM fragrance ingredient safety assessment, acetaldehyde, diphenethyl acetal, CAS Registry Number 122-71-4	23
Update to RIFM fragrance ingredient safety assessment, isoamyl hexanoate, CAS registry number 2198-61-0	23
Acute ivermectin toxicity on skin and brain tissue of adult albino rats: Evaluation of the role of Flumazenil and Vitamin C as new treatment modalities	23
RIFM fragrance ingredient safety assessment, d-8-p-menthene-1,2-epoxide, CAS Registry Number 1195-92-2	23
RIFM fragrance ingredient safety assessment, 3-(methylthio)-1-hexanol, CAS Registry Number 51755-66-9	23
Dermal repeated dose toxicity study of the anti-breast cancer drug Formestane cream in Bama minipig	23
RIFM fragrance ingredient safety assessment, 3-phenylpropionaldehyde, CAS Registry Number 104-53-0	22
RIFM fragrance ingredient safety assessment, 3-hexanone, 5-mercapto-5-methyl-, CAS Registry Number 851768-51-9	22
RIFM fragrance ingredient safety assessment, pyridine, 4-[1(4-,5 or 6)-methylbicyclo[2.2.1]hept-5-en-2-yl]-, CAS Registry Number 862079-91-2	22
Update to RIFM fragrance ingredient safety assessment, hexanoic acid, 4-methyl-, CAS registry number 1561-11-1	22
RIFM fragrance ingredient safety assessment, isopropyl cinnamate, CAS Registry Number 7780-06-5	22
Strawberry tree honey in combination with 5-fluorouracil enhances chemosensitivity in human colon adenocarcinoma cells	22
Carcinogenic and non-carcinogenic risks caused by rice contamination with heavy metals and their effect on the prevalence of cardiovascular disease (Using machine learning)	22
RIFM fragrance ingredient safety assessment, 11-oxahexadecanolide, CAS Registry Number 3391-83-1	22
RIFM fragrance ingredient safety assessment, butyl salicylate, CAS Registry Number 2052-14-4	22
RIFM fragrance ingredient safety assessment, benzoic acid, 2-hydroxy-5-methyl-, methyl ester, CAS Registry Number 22717-57-3	22
Update to RIFM fragrance ingredient safety assessment, dimethyl succinate, CAS Registry Number 106-65-0	22
RIFM fragrance ingredient safety assessment, methyl 4(or 1)-isopropyl-1(or 4)-methylbicyclo[2.2.2]oct-5-ene-2-carboxylate, CAS Registry Number 68966-86-9	22
RIFM fragrance ingredient safety assessment, sclareolide, CAS Registry Number 564-20-5	22
Thymoquinone induces oxidative stress-mediated apoptosis through downregulation of Jak2/STAT3 signaling pathway in human melanoma cells	22
RIFM fragrance ingredient safety assessment, 3,3,5-trimethylcyclohexyl ethyl ether, CAS Registry Number 67583-77-1	22
RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]deca-3,6-diene, 2,6,9,10-tetramethyl-, CAS Registry Number 71078-31-4	22
RIFM fragrance ingredient safety assessment, methyl sorbate, CAS Registry Number 689-89-4	22
Cyanidin-3-O-glucoside and its metabolite protocatechuic acid ameliorate 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induced cytotoxicity in HepG2 cells by regulating apoptotic and Nrf2/p62	22
RIFM fragrance ingredient safety assessment, 4-thujanol, CAS Registry Number 546-79-2	22
Update to RIFM fragrance ingredient safety assessment, β-caryophyllene alcohol, CAS registry number 472-97-9	21
Maternal exposure to a glyphosate-based herbicide impairs placental development through endoplasmic reticulum stress in mice	21
RIFM fragrance ingredient safety assessment, cinnamyl butyrate, CAS Registry Number 103-61-7	21
Protective role of the dried white mulberry extract on the reproductive damage and fertility in rats treated with carmustine	21
A time-course study of microglial activation and dopaminergic neuron loss in the substantia nigra of mice with paraquat-induced Parkinson's disease	21
Normolipidic diet containing deep-fried saturated and unsaturated fatty acids rich edible oils promotes metabolic dysregulation and inflammatory microenvironment in Wistar rats	21
RIFM fragrance ingredient safety assessment, cis-jasmone, CAS registry number 488-10-8	21
Editorial Board	21
RIFM fragrance ingredient safety assessment, isolongifolene oxide, CAS Registry Number 26619-69-2	21
Choice of experimental model determines translational impact: The link between bisphenol A and cardiotoxicity	21
Potential underlying mechanisms of ethambutol induced optic neuropathy: Evidence from in vitro to clinical studies	21
Atrazine-induced oxidative damage via modulating xenobiotic-sensing nuclear receptors and cytochrome P450 systems in cerebrum and antagonism of lycopene	21
In vitro toxicological assessment of aerosols from indirectly heated tobacco products using a solvent-free extraction method	21
Enantioselective toxicity effect and mechanism of hexaconazole enantiomers to human breast cancer cells	21
Editorial Board	21
Bisphenol S exposure induces intestinal inflammation via altering gut microbiome	21
Recent advances in Ponceau dyes monitoring as food colorant substances by electrochemical sensors and developed procedures for their removal from real samples	21
Inhibition of acrylamide toxicity in vivo by arginine-glucose maillard reaction products	21
RIFM fragrance ingredient safety assessment, 2,3,5-trimethylpyrazine, CAS registry number 14667-55-1	21
Update to RIFM fragrance ingredient safety assessment, methyl 2-octynoate, CAS Registry Number 111-12-6	20
Update to RIFM fragrance ingredient safety assessment, isobutyl acetate, CAS Registry Number 110-19-0	20
Corrigendum to “Protracted rosiglitazone treatment exacerbates inflammation in white adipose tissues of adipocyte-specific Nfe2l1 knockout mice” [Food Chem. Toxicol. 146 (2020) 111836]	20
RIFM fragrance ingredient safety assessment, menthol, CAS Registry Number 89-78-1	20
RIFM fragrance ingredient safety assessment, 5(or 6)-methyl-7(or 8)-(1-methylethyl)bicyclo[2.2.2]oct-5-ene-2-carbaldehyde, CAS Registry Number 68259-31-4	20
Exploring quercetin's protective potential against the pro-inflammatory effects of silver nanoparticles in C57BL/6J mice	20