Food and Chemical Toxicology

Article	Citations
RIFM fragrance ingredient safety assessment, acetaldehyde ethyl cis-3-hexenyl acetal, CAS Registry Number 28069-74-1	317
Gut-gonad crosstalk in mice exposed to a “chemical cocktail” combining metabolomics and microbial profile by amplicon sequencing	235
Lithium suppresses the Ras-Raf-MEK-ERK signaling in CD4 T cells and impairs the humoral immune system	186
Update to RIFM fragrance ingredient safety assessment, 3-methylbutanal diethyl acetal, CAS Registry Number 3842-03-3	161
Editorial Board	158
Sustained high expression of NRF2 inhibits cell apoptosis in arsenite-transformed human keratinocytes	148
Investigation and evaluation of gastrointestinal toxicity biomarkers in rats with different sites of gastrointestinal injury	146
Editorial Board	146
Theaflavin alleviates cisplatin-induced nephrotoxicity: Targeting SIRT1/p53/FOXO3a/Nrf2 signaling and the NF-kB inflammatory cascade	138
Update to RIFM fragrance ingredient safety assessment, 3-tert-butylcyclohexyl acetate, CAS Registry Number 31846-06-7	131
Bisphenol A and its analogue bisphenol S exposure reduce estradiol synthesis via the ROS-mediated PERK/ATF4 signaling pathway	119
RIFM natural complex substance (NCS) fragrance ingredient safety assessment, lavandin abrialis, CAS registry number 8022-15-9, RIFM ID 1048554	116
Cardiac oxylipin perturbances in response to 2-monochloropropane-1,3-diol exposure are ameliorated by dietary adequacy of the essential n-3 fatty acid, α-linolenic acid	113
Diisobutyl phthalate (DiBP)-induced male germ cell toxicity and its alleviation approach	109
Tectorigenin ameliorated high-fat diet-induced nonalcoholic fatty liver disease through anti-inflammation and modulating gut microbiota in mice	107
Probiotic lactobacilli attenuate oxysterols-induced alteration of intestinal epithelial cell monolayer permeability: Focus on tight junction modulation	106
Curcumin mitigates gentamicin induced-renal and cardiac toxicity via modulation of Keap1/Nrf2, NF-κB/iNOS and Bcl-2/BAX pathways	103
Silk fibroin peptide self-assembled nanofibers delivered naringenin to alleviate cisplatin-induced acute kidney injury by inhibiting mtDNA-cGAS-STING pathway	100
No-observed adverse effect levels of deoxynivalenol and aflatoxin B1 in combination induced immune inhibition and apoptosis in vivo and in vitro	93
Evaluation of cigarette smoke-induced oxidative stress and inflammation in BEAS-2B cells based on a lung microfluidic chip	90
Functional evaluation of fibroblast-to-myofibroblast transition as an in vitro screening tool for pulmonary fibrosis	84
Microcystin-LR exposure interfered maintenance of colonic microenvironmental homeostasis in rat	80
Update to RIFM fragrance ingredient safety assessment, octyl butyrate, CAS Registry Number 110-39-4	78
Gene expression profiles related to apoptosis and levels of DNA oxidative damage in primary dermal fibroblast cells (ATCC® PCS-201-012TM) treated with zirconium oxide nanoparticles	78
RIFM fragrance ingredient safety assessment, furfural, CAS Registry Number 98-01-1	77

RIFM fragrance ingredient safety assessment, ethyl 2-ethylhexanoate, CAS Registry Number 2983-37-1	71
RIFM fragrance ingredient safety assessment, 2-methylpropyl 2-methylbutyrate, CAS Registry Number 2445-67-2	71
Update to RIFM fragrance ingredient safety assessment, 1-naphthalenol, 1,2,3,4,4a,5,8,8a-octahydro-2,2,6,8-tetramethyl-, CAS Registry Number 103614-86-4	67
RIFM fragrance ingredient safety assessment, bicyclo[2.2.1]heptan-2-ol, 1,3,3-trimethyl-, benzoate, CAS Registry Number 55066-54-1	64
RIFM fragrance ingredient safety assessment, ethyl valerate, CAS Registry Number 539-82-2	62
Update to RIFM fragrance ingredient safety assessment, 2H-inden-2-one, 1,3-dihydro-, CAS Registry Number 615-13-4	62
Update to RIFM fragrance ingredient safety assessment, 4-methylpentanoic acid, CAS Registry Number 646-07-1	60
Update to RIFM fragrance ingredient safety assessment, pentyl benzoate, CAS Registry Number 2049-96-9	59
Sinomenine synergistically enhances 5-Fu anticancer effects in oral cancer through modulating the miR-140-5p-PDK1-anaerobic glycolysis pathway	58
Preclinical toxicity evaluation of the novel anti-hypertensive compound KSD179019	57
RIFM fragrance ingredient safety assessment, 3-buten-2-one, 4-(2,2,3-trimethyl-6-methylenecyclohexyl)-, CAS registry number 79-68-5	57
The role of GSK3β signaling mediated lysosomal biosynthesis dysregulation in fluoride-induced neurological impairment	57
Ultra-fast liquid chromatography detection of β-N-methylamine-l-alanine and its isomers in cycad seeds and cyanobacterial symbionts for neurotoxic risk assessment	56
Assessing the toxic dose of the potent antioxidant 3,5-dihydroxy-4-methoxybenzyl alcohol in rats	56
Update to RIFM fragrance ingredient safety assessment, hexyl isovalerate, CAS Registry Number 10032-13-0	55
Assessment of human health risk concerning edible plants contamination with toxic elements around functional and derelict mines	55
Kidney toxicity and transcriptome analyses of male ICR mice acutely exposed to the mushroom toxin α-amanitin	55
Editorial Board	54
RIFM fragrance ingredient safety assessment, isoeugenyl methyl ether, CAS Registry Number 93-16-3	54
RIFM fragrance ingredient safety assessment, ethyl decanoate, CAS Registry Number 110-38-3	54
EGCG exposure during pregnancy affects uterine histomorphology in F1 female mice and the underlying mechanisms	53
Corrigendum to “In vitro and in vivo antitumor effects of Peanut agglutinin through induction of apoptotic and autophagic cell death” [Food Chem. Toxicol. 2014 64 369-77]	53
RIFM fragrance ingredient safety assessment, 5,8-methano-2H-1-benzopyran, 6(or 7)-ethylideneoctahydro-, [4aR,5S,8S,8aS(or 4aR,5R,8S,8aR)]-rel-, CAS Registry Number 943723-15-7	52
Neurotoxic effect of nalufin on the histology, ultrastructure, cell cycle and apoptosis of the developing chick embryo and its amelioration by selenium	51
The “steric-like” inhibitory effect and mechanism of doxycycline on florfenicol metabolism: Interaction risk	50
NRF-2α and mitophagy underlie enhanced mitochondrial functions and biogenesis induced by T-2 toxin in GH3 cells	50
RIFM fragrance ingredient safety assessment, styrene, CAS Registry Number 100-42-5	50
RIFM fragrance ingredient safety assessment, cis-3-hexenyl isobutyrate, CAS Registry Number 41519-23-7	49
RIFM fragrance ingredient safety assessment, o-(Methylthio)-phenol, CAS Registry Number 1073-29-6	49
RIFM fragrance ingredient safety assessment, 2-pentylcyclopentan-1-ol, CAS Registry Number 84560-00-9	48
RIFM fragrance ingredient safety assessment, hex-3-enyl acetate, CAS Registry Number 1708-82-3	47
Predicting chemicals’ toxicity pathway of female reproductive disorders using AOP7 and deep neural networks	47
RIFM fragrance ingredient safety assessment, isopentyl 2-methylcrotonate (E), CAS Registry Number 41519-18-0	47
RIFM fragrance ingredient safety assessment, 2-acetyl-3-methylpyrazine, CAS Registry number 23787-80-6	47
RIFM fragrance ingredient safety assessment, methyl butyrate, CAS registry number 623-42-7	45
Green synthesized colloidal silver is devoid of toxic effects on primary human nasal epithelial cells in vitro	44
Acrylamide in food: Occurrence, metabolism, molecular toxicity mechanism and detoxification by phytochemicals	44
Inhibition of human sulfotransferases (SULTs) by per- and polyfluoroalkyl substances (PFASs) and structure-activity relationship	44
Toxicity assessment of heavy metals translocation in maize grown in the Ganges delta floodplain soils around the Payra power plant in Bangladesh	43
MiR-93 alleviates DEHP plasticizer-induced neurotoxicity by negatively regulating TNFAIP1 and inhibiting ubiquitin-mediated degradation of CK2β	43
Preclinical safety evaluation of sodium L-methylfolate	43
Low-dose benzo[a]pyrene exposure induces hepatic lipid deposition through LCMT1/PP2Ac-mediated autophagy inhibition	42
Ouabain inhibitor rostafuroxin attenuates dextromethorphan-induced manic potential	42
Identification of non-volatile non-intentionally added substances from polyester food contact coatings and genotoxicity assessment of polyester coating's migrates	42
Comparative detection of E. coli, B. subtilis and their mixture in yam samples by ATP bioluminescence and SERS methods	41
Inhalation toxicity of thermal transformation products formed from e-cigarette vehicle liquid using an in vitro lung model exposed at the Air–Liquid Interface	41
Combined environmental relevant exposure to perfluorooctanoic acid and zinc sulfate enhances apoptosis through binding with endogenous antioxidants in Daphnia magna	40
Farnesol prevents chlorpyrifos nephrotoxicity by modulating inflammatory mediators, Nrf2 and FXR and attenuating oxidative stress	40
From food-to-human microplastics and nanoplastics exposure and health effects: A review on food, animal and human monitoring data	40
Global review, meta-analysis and health risk assessment of Polycyclic Aromatic Hydrocarbons (PAHs) in chicken kebab using Monte Carlo simulation method	40

Gallic, ellagic acids and their oral combined administration induce kidney, lung, and heart injury after acute exposure in Wistar rats	39
Rutin, a natural flavonoid glycoside, ameliorates zearalenone induced liver inflammation via inhibiting lipopolysaccharide gut leakage and NF-κB signaling pathway in mice	39
Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice	38
RIFM fragrance ingredient safety assessment, acetylcarene, CAS Registry Number 3608-11-5	38
Anti-inflammatory action of betulin and its potential as a dissociated glucocorticoid receptor modulator	38
Characterizing the risk related to the exposure to methylmercury over a lifetime: A global approach using population internal exposure	38
Corrigendum to “Rice bran extract mitigates depressive-like behavior in dextran sulfate sodium-induced colitis: Involvement of the gut-brain axis and Sirt1 signaling pathway” [Food and Chemical Toxico	38
Role of MRPs transporters in pharmacokinetics and intestinal toxicity of irinotecan	37
In response to the Letter to the Editor from Xiao regarding our article, “FEMA GRAS assessment of natural flavor complexes: Asafetida oil, garlic oil and onion oil”	37
Kaempferol improves recurrent spontaneous abortion outcomes and prevents oxidative stress damage by inhibiting the NF-kB signaling pathway	36
Melatonin protects against diclofenac induced oxidative stress mediated myocardial toxicity in rats: A mechanistic insight	35
Corrigendum to “Effects of gelatin-based antifreeze peptides on cell viability and oxidant stress of Streptococcus thermophilus during cold stage” [Food Chem. Toxicol. 136 (2020) 111056]	35
Piceatannol upregulates USP14-mediated GPX4 deubiquitination to inhibit neuronal ferroptosis caused by cerebral ischemia-reperfusion in mice	35
N-(2-ozoazepan-3-yl)-pyrrolidine-2-carboxamide, a novel Octopus vulgaris ink-derived metabolite, exhibits a pro-apoptotic effect on A549 cancer cell line and inhibits pro-inflammatory markers	35
RIFM fragrance ingredient safety assessment, d,l-menthone 1,2-glycerol ketal, CAS Registry Number 63187-91-7	35
Experimental evaluation of favipiravir (T-705)-induced liver and kidney toxicity in rats	35
Update to RIFM fragrance ingredient safety assessment, nonyl acetate, CAS registry number 143-13-5	34
RIFM fragrance ingredient safety assessment, germacrene D, CAS Registry Number 23986-74-5	34
RIFM fragrance ingredient safety assessment, 2,4,4,7-tetramethylnona-6,8-diene-3-one-oxime, CAS Registry Number 81783-01-9	34
RIFM fragrance ingredient safety assessment, p-isopropyl phenylacetaldehyde, CAS Registry Number 4395-92-0	34
RIFM fragrance ingredient safety assessment, cycloionone, CAS Registry Number 5552-30-7	34
Epigallocatechin gallate-rich fraction alleviates histamine-induced neurotoxicity in rats via inactivating caspase-3/JNK signaling pathways	34
Update to RIFM fragrance ingredient safety assessment, methyl benzoate, CAS Registry Number 93-58-3	33
RIFM fragrance ingredient safety assessment, dodecahydro-3,8,8,11a-tetramethyl-5H-3,5a-epoxynaphth[2,1-c]oxepin, CAS Registry Number 57345-19-4	33
RIFM fragrance ingredient safety assessment, 3-(p-isopropylphenyl)propionaldehyde, CAS registry number 7775-00-0	32
RIFM fragrance ingredient safety assessment, 3-phenyl-3-buten-1-yl acetate, CAS Registry Number 7306-12-9	32
Update to RIFM fragrance ingredient safety assessment, linalyl acetate, CAS registry number 115-95-7	32
RIFM fragrance ingredient safety assessment, cis- and trans-p-1(7),8-menthadien-2-yl acetate, CAS registry number 71660-03-2	32
Update to RIFM fragrance ingredient safety assessment, p-tolyl alcohol, CAS Registry Number 589-18-4	32
Deoxynivalenol upregulates hypoxia-inducible factor-1α to promote an “immune evasion” process by activating STAT3 signaling	31
RIFM fragrance ingredient safety assessment, ω-6-hexadecenlactone, CAS Registry Number 7779-50-2	31
RIFM fragrance ingredient safety assessment, patchouli alcohol, CAS Registry Number 5986-55-0	31
Organophosphate esters and their metabolites in Beijing total diets: Occurrence, time trend, and dietary exposure assessment	31
Update to RIFM fragrance ingredient safety assessment, methyl phenylacetate, CAS Registry Number 101-41-7	31
RIFM fragrance ingredient safety assessment, o-methoxybenzaldehyde, CAS Registry Number 135-02-4	31
RIFM fragrance ingredient safety assessment, 4-acetoxy-2,5-dimethyl-3(2H)furanone, CAS Registry Number 4166-20-5	31
RIFM fragrance ingredient safety assessment, cedryl formate, CAS Registry Number 39900-38-4	31
RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, tangelo oil, expressed, CAS Registry Number 72869-73-9, RIFM ID 931-G2.5	31
Update to RIFM fragrance ingredient safety assessment, ethyl benzoate, CAS Registry Number 93-89-0	31
Update to RIFM fragrance ingredient safety assessment, menthyl acetate (isomer unspecified), CAS registry number 16409-45-3	31
RIFM fragrance ingredient safety assessment, benzoic acid, 2-[[3-(4-methoxyphenyl)-2-methylpropylidene]amino]-, methyl ester, CAS registry number 111753-62-9	30
Non-allergenic mixed T cell epitope peptides for preventing Scy p 9 allergic reactions	30
Enniatin B and beauvericin affect intestinal cell function and hematological processes in Atlantic salmon (Salmo salar) after acute exposure	30
Determination of acrylamide levels in chips/crisps on the Italian market and exposure risk assessment	30
Active compounds of licorice ameliorate microplastics-induced intestinal damage by targeting FADD	30
Toxicology of Dyes: Editorial Introduction	30
Weighted analysis of 2′-fucosyllactose, 3-fucosyllactose, lacto-N-tetraose, 3′-sialyllactose, and 6′-sialyllactose concentrations in human milk	30
RIFM fragrance ingredient safety assessment, (1aα,4α,7aα)-1a,3,3,4,6,6-hexamethyl-1a,2,3,4,5,6,7,7a-octahydronapth[3,3-b]oxirene, CAS Registry Number 94400-98-3	30
Chronic exposure to B[a]P induces malignant transformation of breast epithelial cells through the mechanism via TGF-β signaling pathway	30
Update to RIFM fragrance ingredient safety assessment, isobutyl propionate, CAS Registry Number 540-42-1	30
Multivariate analysis of potentially toxic metal contents in soil and vegetables: Enrichment, bioconcentration, translocation from soil to vegetables, and assessment of human health toxicity	30
RIFM fragrance ingredient safety assessment, 2-trans-6-cis-dodecadienal, CAS Registry Number 21662-13-5	29
RIFM fragrance ingredient safety assessment, sssmenthadiene-7-methyl formate, CAS registry number 68683-20-5	29
Isochlorogenic acid A ameliorated lead-induced anxiety-like behaviors in mice by inhibiting ferroptosis-mediated neuroinflammation via the BDNF/Nrf2/GPX4 pathways	29
RIFM fragrance ingredient safety assessment, 3-mercaptohexyl acetate, CAS Registry Number 136954-20-6	29
RIFM fragrance ingredient safety assessment, 3-methyl-2-butenyl salicylate, CAS Registry Number 68555-58-8	29
Pithecellobium dulce induces apoptosis and reduce tumor burden in experimental animals via regulating pro-inflammatory cytokines and anti-apoptotic gene expression	29
Editorial Board	29
Editorial Board	28
RIFM fragrance ingredient safety assessment, ethyl butyrate, CAS registry number 105-54-4	28
Update to RIFM fragrance ingredient safety assessment, α,2,2,3-tetramethylcyclopent-3-ene-1-butyraldehyde, CAS Registry Number 65114-03-6	28
RIFM fragrance ingredient safety assessment, 1-formyl-1-methyl-4-(4-methyl-pentyl)-3-cyclohexene, CAS Registry Number 66327-54-6	28
High throughput screening of bisphenols and their mixtures under conditions of low-intensity adipogenesis of human mesenchymal stem cells (hMSCs)	28
RIFM fragrance ingredient safety assessment, bisabolene, CAS registry number 495-62-5	28
RIFM fragrance ingredient safety assessment, benzene, 1-(dimethoxymethyl)-4-methoxy-, CAS Registry Number 2186-92-7	28
Mycotoxins in raw materials, beverages and supplements of botanicals: A review of occurrence, risk assessment and analytical methodologies	28
RIFM fragrance ingredient safety assessment, p-mentha-1,3-diene, CAS Registry Number 99-86-5	28
RIFM fragrance ingredient safety assessment, oxacyclopentadec-10-en-2-one, 13-methyl-, CAS Registry Number 329925-33-9	28
RIFM fragrance ingredient safety assessment, phenethyl propionate, CAS Registry Number 122-70-3	28
RIFM fragrance ingredient safety assessment, 2-phenylhexanenitrile, CAS registry number 3508-98-3	28
RIFM fragrance ingredient safety assessment, 4-methoxy-α-methylbenzenepropanal, CAS Registry Number 5462-06-6	28
RIFM fragrance ingredient safety assessment, 2-ethylhexanal, CAS Registry Number 123-05-7	27
Association between Di-2-ethylhexyl phthalate and nonalcoholic fatty liver disease among US adults: Mediation analysis of body mass index and waist circumference in the NHANES	27
Lanthanum decreased VAPB-PTPP51, BAP31-FIS1, and MFN2-MFN1 expression of mitochondria-associated membranes and induced abnormal autophagy in rat hippocampus	27
Update to RIFM fragrance ingredient safety assessment, trans-2-hexenoic acid, CAS Registry Number 13419-69-7	27
Alcohol induces hepatocytes necroptosis through the LC3/RIPK1/RIPK3 pathway	27
Triptolide exposure triggers ovarian inflammation by activating cGAS-STING pathway and decrease oocyte quality in mouse	27
RIFM fragrance ingredient safety assessment, 1,1-dimethyl-2-phenylethyl acetate, CAS registry number 151-05-3	27
Fertility-enhancing effects of inositol & vitamin C on cisplatin induced ovarian and uterine toxicity in rats via suppressing oxidative stress and apoptosis	27
Rapid identification of counterfeited beef using deep learning-aided spectroscopy: Detecting colourant and curing agent adulteration	27

Apigenin in cancer therapy: From mechanism of action to nano-therapeutic agent	26
Hyperoside attenuates Cd-induced kidney injury via inhibiting NLRP3 inflammasome activation and ROS/MAPK/NF-κB signaling pathway in vivo and in vitro	26
Development and application of an interactive generic physiologically based pharmacokinetic (igPBPK) model for adult beef cattle and lactating dairy cows to estimate tissue distribution and edible tis	26
Bisphenol a exposure decreases learning ability through the suppression of mitochondrial oxidative phosphorylation in the hippocampus of male mice	26
Emamectin benzoate-induced toxicity affects intestinal epithelial integrity involving apoptosis	26
Mitigating Bisphenol-Induced Neurotoxicity: Exploring the Therapeutic Potential of Diosmin in Zebrafish Larvae	26
Chlorinated organophosphorus flame retardants-induced mitochondrial abnormalities and the correlation with progesterone production in mLTC-1 cells	26
An integrated strategy combining network toxicology and feature-based molecular networking for exploring hepatotoxic constituents and mechanism of Epimedii Folium-induced hepatotoxicity in vitro	26
Impact of food matrices on the characteristics and cellular toxicities of ingested nanoplastics in a simulated digestive tract	26
CDKN1A promotes Cis-induced AKI by inducing cytoplasmic ROS production and ferroptosis	25
Update to RIFM fragrance ingredient safety assessment, benzyl formate, CAS Registry Number 104-57-4	25
Hyoscyamine induces developmental toxicity by disrupting metabolism in zebrafish embryo (Danio rerio)	25
Immunoproteasome subunit PSMB8 regulates microglia-mediated neuroinflammation upon manganese exposure by PERK signaling	25
Bisphenol S exposure induces cytotoxicity in mouse Leydig cells	25
The current understanding of the benefits, safety, and regulation of cannabidiol in consumer products	25
Therapeutic potential of 2S-hesperidin against the hepatotoxic effects of dichlorvos in rats	25
In silico and in vitro safety assessment of a fungal biomass from Rhizomucor pusillus for use as a novel food ingredient	25
Probiotic cultures as a potential protective strategy against the toxicity of environmentally relevant chemicals: State-of-the-art knowledge	25
Environmental toxicity risk evaluation of nitroaromatic compounds: Machine learning driven binary/multiple classification and design of safe alternatives	25
Liensinine, a alkaloid from lotus plumule, mitigates lipopolysaccharide-induced sepsis-associated encephalopathy through modulation of nuclear factor erythroid 2-related factor-mediated inflammatory b	25
Dietary exposure to mixtures of chemicals in the first year of life and allergic and respiratory diseases up to 8 years in the French EDEN mother-child cohort	25
Glyphosate and AMPA-induced apoptosis and epigenetic alterations in HepG2 Cells: Upregulation of p53-BAX-CASP pathways	25
Unravelling the anti-inflammatory and antioxidant effects of standardized green and black caffeinated coffee, tea, and their mixtures in an obese male rat model: Insights from biochemical, metabolomic	25
RIFM fragrance ingredient safety assessment, 1-propanol, 2-methyl-3-[(1,7,7-trimethylbicyclo-[2.2.1]hept-2-yl)oxy]-, CAS Registry Number 128119-70-0	24
RIFM fragrance ingredient safety assessment, butyl salicylate, CAS Registry Number 2052-14-4	24
RIFM fragrance ingredient safety assessment, 3-hexanone, 5-mercapto-5-methyl-, CAS Registry Number 851768-51-9	24
Update to RIFM fragrance ingredient safety assessment, hexanoic acid, 4-methyl-, CAS registry number 1561-11-1	24
RIFM fragrance ingredient safety assessment, pyridine, 4-[1(4-,5 or 6)-methylbicyclo[2.2.1]hept-5-en-2-yl]-, CAS Registry Number 862079-91-2	24
Acute ivermectin toxicity on skin and brain tissue of adult albino rats: Evaluation of the role of Flumazenil and Vitamin C as new treatment modalities	24
RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]deca-3,6-diene, 2,6,9,10-tetramethyl-, CAS Registry Number 71078-31-4	24
RIFM fragrance ingredient safety assessment, 3,3,5-trimethylcyclohexyl ethyl ether, CAS Registry Number 67583-77-1	24
Potential underlying mechanisms of ethambutol induced optic neuropathy: Evidence from in vitro to clinical studies	24
Mitochondrial damage precedes the changes of glutathione metabolism in CdCl2 treated neuronal SH-SY5Y cells	24
Update to RIFM fragrance ingredient safety assessment, acetaldehyde, diphenethyl acetal, CAS Registry Number 122-71-4	24
RIFM fragrance ingredient safety assessment, benzoic acid, 2-hydroxy-5-methyl-, methyl ester, CAS Registry Number 22717-57-3	24
RIFM fragrance ingredient safety assessment, 11-oxahexadecanolide, CAS Registry Number 3391-83-1	24
RIFM fragrance ingredient safety assessment, methyl sorbate, CAS Registry Number 689-89-4	24
RIFM fragrance ingredient safety assessment, cis-jasmone, CAS registry number 488-10-8	23
RIFM fragrance ingredient safety assessment, d-8-p-menthene-1,2-epoxide, CAS Registry Number 1195-92-2	23
Normolipidic diet containing deep-fried saturated and unsaturated fatty acids rich edible oils promotes metabolic dysregulation and inflammatory microenvironment in Wistar rats	23
RIFM fragrance ingredient safety assessment, thymol, CAS Registry Number 89-83-8	23
RIFM fragrance ingredient safety assessment, sclareolide, CAS Registry Number 564-20-5	23
Dermal repeated dose toxicity study of the anti-breast cancer drug Formestane cream in Bama minipig	23
Sub-acute administration of metal-organic Framework-5 induces behavioral impairments and augments the levels of oxidative stress and inflammation in the brain of rats	23
Bisphenol S exposure induces intestinal inflammation via altering gut microbiome	23
RIFM fragrance ingredient safety assessment, 3-phenylpropionaldehyde, CAS Registry Number 104-53-0	23
RIFM fragrance ingredient safety assessment, methyl 4(or 1)-isopropyl-1(or 4)-methylbicyclo[2.2.2]oct-5-ene-2-carboxylate, CAS Registry Number 68966-86-9	23
Bioactive extract of Morchella esculenta ameliorates cyclophosphamide-induced mitochondrial dysfunction and cardiotoxicity by modulating KEAP1/NRF2 and pro-inflammatory genes expression	23
Neurotoxicity of dibutyl phthalate in zebrafish larvae: Decreased energy acquisition by neurons	22
Update to RIFM fragrance ingredient safety assessment, β-caryophyllene alcohol, CAS registry number 472-97-9	22
Risk assessment of potentially toxic trace elements via consumption of dairy products sold in the city of Yerevan, Armenia	22
Metabolic effects of chronic exposure to environmentally relevant concentrations of N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) in mice during diet-induced obesity progression	22
In vitro toxicological assessment of aerosols from indirectly heated tobacco products using a solvent-free extraction method	22
Fluquinconazole disrupts calcium and mitochondrial homeostasis, leading to bovine mammary epithelial cell death	22
Editorial Board	22
The toxicity of lead on human neuroblastoma cells was alleviated by HUC-MSC-derived exosomes through miR-26a-5p/PTEN pathway	22
Mechanisms of PDC-induced testicular Toxicity: Oxidative stress, steroidogenic suppression, and modulation by ZnO-NP/TEO synergy	22
PAK1 mediates ivermectin-induced DNA damage in porcine oocytes during meiotic maturation	22
Bisphenol analogues inhibit human and rat 17β-hydroxysteroid dehydrogenase 1: 3D-quantitative structure-activity relationship (3D-QSAR) and in silico docking analysis	22
RIFM fragrance ingredient safety assessment, isolongifolene oxide, CAS Registry Number 26619-69-2	22
Thymoquinone induces oxidative stress-mediated apoptosis through downregulation of Jak2/STAT3 signaling pathway in human melanoma cells	22
RIFM fragrance ingredient safety assessment, methyl p-methylbenzoate, CAS Registry Number 99-75-2	22
Tri-ortho-cresyl phosphate causes glucose intolerance and insulin resistance in mice by inducing oxidative stress	22
Pharmacokinetics and 28-day repeated-dose toxicity of enniatin B after oral administration in mice	22
RIFM fragrance ingredient safety assessment, 2,3,5-trimethylpyrazine, CAS registry number 14667-55-1	21
Update to RIFM fragrance ingredient safety assessment, isoamyl hexanoate, CAS registry number 2198-61-0	21
Imatinib disturbs lysosomal function and morphology and impairs the activity of mTORC1 in human hepatocyte cell lines	21
Vallaris solanacea induces mitochondrial mediated apoptosis in HL-60 human promyelocytic leukemia cells	21
Update to RIFM fragrance ingredient safety assessment, dimethyl succinate, CAS Registry Number 106-65-0	21
Maternal exposure to a glyphosate-based herbicide impairs placental development through endoplasmic reticulum stress in mice	21
Potential exacerbation of polycystic ovary syndrome by saccharin sodium Via taste receptors in a letrozole rat model	21
Review of the oral toxicity of cannabidiol (CBD)	21
Protective role of the dried white mulberry extract on the reproductive damage and fertility in rats treated with carmustine	21
Choice of experimental model determines translational impact: The link between bisphenol A and cardiotoxicity	21
RIFM fragrance ingredient safety assessment, 4-thujanol, CAS Registry Number 546-79-2	21
Genetic variations of CYP3A4 on the metabolism of itraconazole in vitro	21
Editorial Board	21
A time-course study of microglial activation and dopaminergic neuron loss in the substantia nigra of mice with paraquat-induced Parkinson's disease	20
Endogenous hydrogen sulfide counteracts polystyrene nanoplastics-induced mitochondrial apoptosis and excessive autophagy via regulating Nrf2 and PGC-1α signaling pathway in mouse spermatocyte-derived	20
Enantioselective toxicity effect and mechanism of hexaconazole enantiomers to human breast cancer cells	20
An in vitro protocol to characterise the resistance of food proteins to intestinal digestion	20
High fructose-induced skeletal muscle insulin resistance could be alleviated by berberine via AMPD1 and ADSL	20
Atrazine-induced oxidative damage via modulating xenobiotic-sensing nuclear receptors and cytochrome P450 systems in cerebrum and antagonism of lycopene	20
Safety and toxicologic evaluation of Edible Pongamia Oil: A novel food ingredient	20
Ultrasensitive electrochemical sensor for detection of rutin antioxidant by layered Ti3Al0.5Cu0.5C2 MAX phase	20
Investigation of eight cellulose nanomaterials’ impact on Differentiated Caco-2 monolayer integrity and cytotoxicity	20
Perfluorohexane sulfonate (PFHxS) induces liver cytotoxicity by activating autophagy and endoplasmic reticulum stress-regulated mitochondrial pathway apoptosis	20
Endocrine disruptor hexachlorobenzene induces cell migration and invasion, and enhances aromatase expression levels in human endometrial stromal cells	20
Carcinogenic and non-carcinogenic risks caused by rice contamination with heavy metals and their effect on the prevalence of cardiovascular disease (Using machine learning)	20
Recent advances in Ponceau dyes monitoring as food colorant substances by electrochemical sensors and developed procedures for their removal from real samples	20
RIFM fragrance ingredient safety assessment, anisyl acetate (isomer unspecified), CAS Registry Number 1331-83-5	19
RIFM fragrance ingredient safety assessment, ethyl benzoylacetate, CAS registry number 94-02-0	19
Update to RIFM fragrance ingredient safety assessment, 2-methylvaleric acid, CAS Registry Number 97-61-0	19
RIFM fragrance ingredient safety assessment, benzoic acid, 2-[(2-phenylethylidene)amino]-, methyl ester, CAS Registry Number 67785-76-6	19
In vitro cytotoxicity assessment of carbonaceous gels for bone marrow mesenchymal stem cells	19