Food and Chemical Toxicology

Papers
(The TQCC of Food and Chemical Toxicology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
RIFM fragrance ingredient safety assessment, acetaldehyde ethyl cis-3-hexenyl acetal, CAS Registry Number 28069-74-1307
Ouabain inhibitor rostafuroxin attenuates dextromethorphan-induced manic potential230
Gut-gonad crosstalk in mice exposed to a “chemical cocktail” combining metabolomics and microbial profile by amplicon sequencing157
No-observed adverse effect levels of deoxynivalenol and aflatoxin B1 in combination induced immune inhibition and apoptosis in vivo and in vitro152
Sustained high expression of NRF2 inhibits cell apoptosis in arsenite-transformed human keratinocytes143
Investigation and evaluation of gastrointestinal toxicity biomarkers in rats with different sites of gastrointestinal injury137
Editorial Board133
Corrigendum to “In vitro and in vivo antitumor effects of Peanut agglutinin through induction of apoptotic and autophagic cell death” [Food Chem. Toxicol. 2014 64 369-77]130
Editorial Board127
Microcystin-LR exposure interfered maintenance of colonic microenvironmental homeostasis in rat126
Inhibition of human sulfotransferases (SULTs) by per- and polyfluoroalkyl substances (PFASs) and structure-activity relationship116
Gallic, ellagic acids and their oral combined administration induce kidney, lung, and heart injury after acute exposure in Wistar rats115
Anti-inflammatory action of betulin and its potential as a dissociated glucocorticoid receptor modulator112
RIFM fragrance ingredient safety assessment, cis-3-hexenyl isobutyrate, CAS Registry Number 41519-23-7109
RIFM fragrance ingredient safety assessment, o-(Methylthio)-phenol, CAS Registry Number 1073-29-698
Editorial Board97
RIFM fragrance ingredient safety assessment, dihydrocarvyl acetate, CAS Registry Number 20777-49-597
Update to RIFM fragrance ingredient safety assessment, 3-methylbutanal diethyl acetal, CAS Registry Number 3842-03-395
RIFM fragrance ingredient safety assessment, hex-3-enyl acetate, CAS Registry Number 1708-82-393
RIFM fragrance ingredient safety assessment, 5,8-methano-2H-1-benzopyran, 6(or 7)-ethylideneoctahydro-, [4aR,5S,8S,8aS(or 4aR,5R,8S,8aR)]-rel-, CAS Registry Number 943723-15-790
RIFM fragrance ingredient safety assessment, 11-tridecen-6-one, 8,12-dimethyl-, CAS Registry Number 68141-18-489
Toxicity assessment of heavy metals translocation in maize grown in the Ganges delta floodplain soils around the Payra power plant in Bangladesh87
Probiotic lactobacilli attenuate oxysterols-induced alteration of intestinal epithelial cell monolayer permeability: Focus on tight junction modulation86
Kidney toxicity and transcriptome analyses of male ICR mice acutely exposed to the mushroom toxin α-amanitin79
Bisphenol A and its analogue bisphenol S exposure reduce estradiol synthesis via the ROS-mediated PERK/ATF4 signaling pathway76
Ultra-fast liquid chromatography detection of β-N-methylamine-l-alanine and its isomers in cycad seeds and cyanobacterial symbionts for neurotoxic risk assessment75
Curcumin mitigates gentamicin induced-renal and cardiac toxicity via modulation of Keap1/Nrf2, NF-κB/iNOS and Bcl-2/BAX pathways73
Cardiac oxylipin perturbances in response to 2-monochloropropane-1,3-diol exposure are ameliorated by dietary adequacy of the essential n-3 fatty acid, α-linolenic acid73
Assessing the toxic dose of the potent antioxidant 3,5-dihydroxy-4-methoxybenzyl alcohol in rats71
Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice69
Assessment of human health risk concerning edible plants contamination with toxic elements around functional and derelict mines67
Sinomenine synergistically enhances 5-Fu anticancer effects in oral cancer through modulating the miR-140-5p-PDK1-anaerobic glycolysis pathway66
Combined environmental relevant exposure to perfluorooctanoic acid and zinc sulfate enhances apoptosis through binding with endogenous antioxidants in Daphnia magna65
Identification of non-volatile non-intentionally added substances from polyester food contact coatings and genotoxicity assessment of polyester coating's migrates60
Silk fibroin peptide self-assembled nanofibers delivered naringenin to alleviate cisplatin-induced acute kidney injury by inhibiting mtDNA-cGAS-STING pathway60
RIFM fragrance ingredient safety assessment, 3-buten-2-one, 4-(2,2,3-trimethyl-6-methylenecyclohexyl)-, CAS registry number 79-68-559
The role of GSK3β signaling mediated lysosomal biosynthesis dysregulation in fluoride-induced neurological impairment57
Predicting chemicals’ toxicity pathway of female reproductive disorders using AOP7 and deep neural networks53
Preclinical toxicity evaluation of the novel anti-hypertensive compound KSD17901953
RIFM fragrance ingredient safety assessment, 2-pentylcyclopentan-1-ol, CAS Registry Number 84560-00-952
Gene expression profiles related to apoptosis and levels of DNA oxidative damage in primary dermal fibroblast cells (ATCC® PCS-201-012TM) treated with zirconium oxide nanoparticles52
EGCG exposure during pregnancy affects uterine histomorphology in F1 female mice and the underlying mechanisms52
Update to RIFM fragrance ingredient safety assessment, 1-naphthalenol, 1,2,3,4,4a,5,8,8a-octahydro-2,2,6,8-tetramethyl-, CAS Registry Number 103614-86-451
RIFM fragrance ingredient safety assessment, ethyl 2-ethylhexanoate, CAS Registry Number 2983-37-151
RIFM fragrance ingredient safety assessment, 2-methylpropyl 2-methylbutyrate, CAS Registry Number 2445-67-251
RIFM fragrance ingredient safety assessment, 2-acetyl-3-methylpyrazine, CAS Registry number 23787-80-650
RIFM fragrance ingredient safety assessment, bicyclo[2.2.1]heptan-2-ol, 1,3,3-trimethyl-, benzoate, CAS Registry Number 55066-54-150
RIFM fragrance ingredient safety assessment, ethyl valerate, CAS Registry Number 539-82-249
Update to RIFM fragrance ingredient safety assessment, 4-methylpentanoic acid, CAS Registry Number 646-07-148
Update to RIFM fragrance ingredient safety assessment, 2H-inden-2-one, 1,3-dihydro-, CAS Registry Number 615-13-448
Update to RIFM fragrance ingredient safety assessment, pentyl benzoate, CAS Registry Number 2049-96-947
RIFM natural complex substance (NCS) fragrance ingredient safety assessment, lavandin abrialis, CAS registry number 8022-15-9, RIFM ID 104855447
RIFM fragrance ingredient safety assessment, furfural, CAS Registry Number 98-01-147
Update to RIFM fragrance ingredient safety assessment, octyl butyrate, CAS Registry Number 110-39-447
Update to RIFM fragrance ingredient safety assessment, hexyl isovalerate, CAS Registry Number 10032-13-046
Green synthesized colloidal silver is devoid of toxic effects on primary human nasal epithelial cells in vitro46
RIFM fragrance ingredient safety assessment, α-amylcinnamaldehyde dimethyl acetal, CAS Registry Number 91-87-246
RIFM fragrance ingredient safety assessment, ethyl decanoate, CAS Registry Number 110-38-345
RIFM fragrance ingredient safety assessment, styrene, CAS Registry Number 100-42-545
Neurotoxic effect of nalufin on the histology, ultrastructure, cell cycle and apoptosis of the developing chick embryo and its amelioration by selenium44
The “steric-like” inhibitory effect and mechanism of doxycycline on florfenicol metabolism: Interaction risk44
RIFM fragrance ingredient safety assessment, isopentyl 2-methylcrotonate (E), CAS Registry Number 41519-18-044
RIFM fragrance ingredient safety assessment, methyl butyrate, CAS registry number 623-42-744
RIFM fragrance ingredient safety assessment, isoeugenyl methyl ether, CAS Registry Number 93-16-344
Inhalation toxicity of thermal transformation products formed from e-cigarette vehicle liquid using an in vitro lung model exposed at the Air–Liquid Interface44
MiR-93 alleviates DEHP plasticizer-induced neurotoxicity by negatively regulating TNFAIP1 and inhibiting ubiquitin-mediated degradation of CK2β43
Ellagitannins from jabuticaba (Myrciaria jaboticaba) seeds attenuated inflammation, oxidative stress, aberrant crypt foci, and modulated gut microbiota in rats with 1,2 dimethyl hydrazine-induced colo43
Global review, meta-analysis and health risk assessment of Polycyclic Aromatic Hydrocarbons (PAHs) in chicken kebab using Monte Carlo simulation method42
Evaluation of cigarette smoke-induced oxidative stress and inflammation in BEAS-2B cells based on a lung microfluidic chip42
Low-dose benzo[a]pyrene exposure induces hepatic lipid deposition through LCMT1/PP2Ac-mediated autophagy inhibition41
NRF-2α and mitophagy underlie enhanced mitochondrial functions and biogenesis induced by T-2 toxin in GH3 cells41
Acrylamide in food: Occurrence, metabolism, molecular toxicity mechanism and detoxification by phytochemicals40
Deoxynivalenol exposure induces liver damage in mice: Inflammation and immune responses, oxidative stress, and protective effects of Lactobacillus rhamnosus GG39
From food-to-human microplastics and nanoplastics exposure and health effects: A review on food, animal and human monitoring data39
Farnesol prevents chlorpyrifos nephrotoxicity by modulating inflammatory mediators, Nrf2 and FXR and attenuating oxidative stress39
Tectorigenin ameliorated high-fat diet-induced nonalcoholic fatty liver disease through anti-inflammation and modulating gut microbiota in mice39
Diisobutyl phthalate (DiBP)-induced male germ cell toxicity and its alleviation approach39
High throughput screening of bisphenols and their mixtures under conditions of low-intensity adipogenesis of human mesenchymal stem cells (hMSCs)38
Multivariate analysis of potentially toxic metal contents in soil and vegetables: Enrichment, bioconcentration, translocation from soil to vegetables, and assessment of human health toxicity38
RIFM fragrance ingredient safety assessment, 3-mercaptohexyl acetate, CAS Registry Number 136954-20-638
Theaflavin alleviates cisplatin-induced nephrotoxicity: Targeting SIRT1/p53/FOXO3a/Nrf2 signaling and the NF-kB inflammatory cascade38
Mycotoxins in raw materials, beverages and supplements of botanicals: A review of occurrence, risk assessment and analytical methodologies38
Mitigating Bisphenol-Induced Neurotoxicity: Exploring the Therapeutic Potential of Diosmin in Zebrafish Larvae38
Rutin, a natural flavonoid glycoside, ameliorates zearalenone induced liver inflammation via inhibiting lipopolysaccharide gut leakage and NF-κB signaling pathway in mice38
Characterizing the risk related to the exposure to methylmercury over a lifetime: A global approach using population internal exposure37
Update to RIFM fragrance ingredient safety assessment, methyl phenylacetate, CAS Registry Number 101-41-737
Rapid identification of counterfeited beef using deep learning-aided spectroscopy: Detecting colourant and curing agent adulteration37
RIFM fragrance ingredient safety assessment, ethyl butyrate, CAS registry number 105-54-437
GPx-1-encoded adenoviral vector attenuates dopaminergic impairments induced by methamphetamine in GPx-1 knockout mice through modulation of NF-κB transcription factor37
RIFM Natural Complex Substance (NCS) fragrance ingredient safety assessment, tangelo oil, expressed, CAS Registry Number 72869-73-9, RIFM ID 931-G2.536
RIFM fragrance ingredient safety assessment, ω-6-hexadecenlactone, CAS Registry Number 7779-50-235
RIFM fragrance ingredient safety assessment, patchouli alcohol, CAS Registry Number 5986-55-035
Update to RIFM fragrance ingredient safety assessment, trans-2-hexenoic acid, CAS Registry Number 13419-69-735
RIFM fragrance ingredient safety assessment, o-methoxybenzaldehyde, CAS Registry Number 135-02-434
Update to RIFM fragrance ingredient safety assessment, menthyl acetate (isomer unspecified), CAS registry number 16409-45-334
Update to RIFM fragrance ingredient safety assessment, ethyl benzoate, CAS Registry Number 93-89-034
RIFM fragrance ingredient safety assessment, benzene, 1-(dimethoxymethyl)-4-methoxy-, CAS Registry Number 2186-92-733
RIFM fragrance ingredient safety assessment, 3-(p-isopropylphenyl)propionaldehyde, CAS registry number 7775-00-032
Update to RIFM fragrance ingredient safety assessment, methyl benzoate, CAS Registry Number 93-58-332
Update to RIFM fragrance ingredient safety assessment, linalyl acetate, CAS registry number 115-95-732
RIFM fragrance ingredient safety assessment, dodecahydro-3,8,8,11a-tetramethyl-5H-3,5a-epoxynaphth[2,1-c]oxepin, CAS Registry Number 57345-19-432
RIFM fragrance ingredient safety assessment, germacrene D, CAS Registry Number 23986-74-532
Update to RIFM fragrance ingredient safety assessment, p-tolyl alcohol, CAS Registry Number 589-18-432
RIFM fragrance ingredient safety assessment, p-isopropyl phenylacetaldehyde, CAS Registry Number 4395-92-032
RIFM fragrance ingredient safety assessment, 3-phenyl-3-buten-1-yl acetate, CAS Registry Number 7306-12-931
RIFM fragrance ingredient safety assessment, pinocarvyl acetate, CAS Registry Number 1078-95-131
RIFM fragrance ingredient safety assessment, oxacyclopentadec-10-en-2-one, 13-methyl-, CAS Registry Number 329925-33-931
RIFM fragrance ingredient safety assessment, phenethyl propionate, CAS Registry Number 122-70-331
Update to RIFM fragrance ingredient safety assessment, nonyl acetate, CAS registry number 143-13-531
Epigallocatechin gallate-rich fraction alleviates histamine-induced neurotoxicity in rats via inactivating caspase-3/JNK signaling pathways31
RIFM fragrance ingredient safety assessment, cis- and trans-p-1(7),8-menthadien-2-yl acetate, CAS registry number 71660-03-231
RIFM fragrance ingredient safety assessment, d,l-menthone 1,2-glycerol ketal, CAS Registry Number 63187-91-731
RIFM fragrance ingredient safety assessment, 6-methyl-5-hepten-2-one, CAS registry number 110-93-031
RIFM fragrance ingredient safety assessment, 2-trans-6-cis-dodecadienal, CAS Registry Number 21662-13-530
RIFM fragrance ingredient safety assessment, 1,1-dimethyl-2-phenylethyl acetate, CAS registry number 151-05-330
RIFM fragrance ingredient safety assessment, 2,4,4,7-tetramethylnona-6,8-diene-3-one-oxime, CAS Registry Number 81783-01-930
RIFM fragrance ingredient safety assessment, 2-phenylhexanenitrile, CAS registry number 3508-98-330
RIFM fragrance ingredient safety assessment, cycloionone, CAS Registry Number 5552-30-730
Fertility-enhancing effects of inositol & vitamin C on cisplatin induced ovarian and uterine toxicity in rats via suppressing oxidative stress and apoptosis29
RIFM fragrance ingredient safety assessment, 4-methoxy-α-methylbenzenepropanal, CAS Registry Number 5462-06-629
RIFM fragrance ingredient safety assessment, bisabolene, CAS registry number 495-62-529
CDKN1A promotes Cis-induced AKI by inducing cytoplasmic ROS production and ferroptosis29
RIFM fragrance ingredient safety assessment, 2-ethylhexanal, CAS Registry Number 123-05-729
Bisphenol S exposure induces cytotoxicity in mouse Leydig cells29
Update to RIFM fragrance ingredient safety assessment, α,2,2,3-tetramethylcyclopent-3-ene-1-butyraldehyde, CAS Registry Number 65114-03-629
RIFM fragrance ingredient safety assessment, 1-formyl-1-methyl-4-(4-methyl-pentyl)-3-cyclohexene, CAS Registry Number 66327-54-629
Isochlorogenic acid A ameliorated lead-induced anxiety-like behaviors in mice by inhibiting ferroptosis-mediated neuroinflammation via the BDNF/Nrf2/GPX4 pathways28
Weighted analysis of 2′-fucosyllactose, 3-fucosyllactose, lacto-N-tetraose, 3′-sialyllactose, and 6′-sialyllactose concentrations in human milk28
Development and application of an interactive generic physiologically based pharmacokinetic (igPBPK) model for adult beef cattle and lactating dairy cows to estimate tissue distribution and edible tis28
RIFM fragrance ingredient safety assessment, 4-acetoxy-2,5-dimethyl-3(2H)furanone, CAS Registry Number 4166-20-528
Nutraceutical intervention protects against bacterial and chemical-induced gastrotoxicity in a non-mammalian model, Galleria mellonella28
Triptolide exposure triggers ovarian inflammation by activating cGAS-STING pathway and decrease oocyte quality in mouse28
An integrated strategy combining network toxicology and feature-based molecular networking for exploring hepatotoxic constituents and mechanism of Epimedii Folium-induced hepatotoxicity in vitro27
Corrigendum to “Rice bran extract mitigates depressive-like behavior in dextran sulfate sodium-induced colitis: Involvement of the gut-brain axis and Sirt1 signaling pathway” [Food and Chemical Toxico27
Corrigendum to “Effects of gelatin-based antifreeze peptides on cell viability and oxidant stress of Streptococcus thermophilus during cold stage” [Food Chem. Toxicol. 136 (2020) 111056]27
RIFM fragrance ingredient safety assessment, acetylcarene, CAS Registry Number 3608-11-527
In silico and in vitro safety assessment of a fungal biomass from Rhizomucor pusillus for use as a novel food ingredient27
N-(2-ozoazepan-3-yl)-pyrrolidine-2-carboxamide, a novel Octopus vulgaris ink-derived metabolite, exhibits a pro-apoptotic effect on A549 cancer cell line and inhibits pro-inflammatory markers27
RIFM fragrance ingredient safety assessment, cedryl formate, CAS Registry Number 39900-38-427
Editorial Board27
Lanthanum decreased VAPB-PTPP51, BAP31-FIS1, and MFN2-MFN1 expression of mitochondria-associated membranes and induced abnormal autophagy in rat hippocampus27
Toxicology of Dyes: Editorial Introduction27
RIFM fragrance ingredient safety assessment, (1aα,4α,7aα)-1a,3,3,4,6,6-hexamethyl-1a,2,3,4,5,6,7,7a-octahydronapth[3,3-b]oxirene, CAS Registry Number 94400-98-327
RIFM fragrance ingredient safety assessment, sssmenthadiene-7-methyl formate, CAS registry number 68683-20-527
Role of MRPs transporters in pharmacokinetics and intestinal toxicity of irinotecan26
Emamectin benzoate-induced toxicity affects intestinal epithelial integrity involving apoptosis26
Melatonin protects against diclofenac induced oxidative stress mediated myocardial toxicity in rats: A mechanistic insight26
Liensinine, a alkaloid from lotus plumule, mitigates lipopolysaccharide-induced sepsis-associated encephalopathy through modulation of nuclear factor erythroid 2-related factor-mediated inflammatory b26
Unravelling the anti-inflammatory and antioxidant effects of standardized green and black caffeinated coffee, tea, and their mixtures in an obese male rat model: Insights from biochemical, metabolomic26
Determination of acrylamide levels in chips/crisps on the Italian market and exposure risk assessment26
Pithecellobium dulce induces apoptosis and reduce tumor burden in experimental animals via regulating pro-inflammatory cytokines and anti-apoptotic gene expression26
In response to the Letter to the Editor from Xiao regarding our article, “FEMA GRAS assessment of natural flavor complexes: Asafetida oil, garlic oil and onion oil”26
Piceatannol upregulates USP14-mediated GPX4 deubiquitination to inhibit neuronal ferroptosis caused by cerebral ischemia-reperfusion in mice26
Comparison of the toxicity of pure compounds and commercial formulations of imidacloprid and acetamiprid on HT-29 cells: Single and mixture exposure26
RIFM fragrance ingredient safety assessment, 3-methyl-2-butenyl salicylate, CAS Registry Number 68555-58-826
Chlorinated organophosphorus flame retardants-induced mitochondrial abnormalities and the correlation with progesterone production in mLTC-1 cells26
Update to RIFM fragrance ingredient safety assessment, isobutyl propionate, CAS Registry Number 540-42-126
RIFM fragrance ingredient safety assessment, p-mentha-1,3-diene, CAS Registry Number 99-86-526
Hyoscyamine induces developmental toxicity by disrupting metabolism in zebrafish embryo (Danio rerio)26
Deoxynivalenol upregulates hypoxia-inducible factor-1α to promote an “immune evasion” process by activating STAT3 signaling26
Bisphenol a exposure decreases learning ability through the suppression of mitochondrial oxidative phosphorylation in the hippocampus of male mice26
Editorial Board26
Non-allergenic mixed T cell epitope peptides for preventing Scy p 9 allergic reactions26
Organophosphate esters and their metabolites in Beijing total diets: Occurrence, time trend, and dietary exposure assessment26
The key role of autophagy in silver nanoparticle-induced BV2 cells inflammation and polarization25
Apigenin in cancer therapy: From mechanism of action to nano-therapeutic agent25
Alcohol induces hepatocytes necroptosis through the LC3/RIPK1/RIPK3 pathway25
Immunoproteasome subunit PSMB8 regulates microglia-mediated neuroinflammation upon manganese exposure by PERK signaling25
Kaempferol improves recurrent spontaneous abortion outcomes and prevents oxidative stress damage by inhibiting the NF-kB signaling pathway25
Experimental evaluation of favipiravir (T-705)-induced liver and kidney toxicity in rats25
Association between Di-2-ethylhexyl phthalate and nonalcoholic fatty liver disease among US adults: Mediation analysis of body mass index and waist circumference in the NHANES25
Genetic variations of CYP3A4 on the metabolism of itraconazole in vitro24
Dietary exposure to mixtures of chemicals in the first year of life and allergic and respiratory diseases up to 8 years in the French EDEN mother-child cohort24
Endocrine disruptor hexachlorobenzene induces cell migration and invasion, and enhances aromatase expression levels in human endometrial stromal cells24
Hyperoside attenuates Cd-induced kidney injury via inhibiting NLRP3 inflammasome activation and ROS/MAPK/NF-κB signaling pathway in vivo and in vitro24
Enniatin B and beauvericin affect intestinal cell function and hematological processes in Atlantic salmon (Salmo salar) after acute exposure24
Probiotic cultures as a potential protective strategy against the toxicity of environmentally relevant chemicals: State-of-the-art knowledge24
Therapeutic potential of 2S-hesperidin against the hepatotoxic effects of dichlorvos in rats24
Neurotoxicity of dibutyl phthalate in zebrafish larvae: Decreased energy acquisition by neurons24
Environmental toxicity risk evaluation of nitroaromatic compounds: Machine learning driven binary/multiple classification and design of safe alternatives24
The current understanding of the benefits, safety, and regulation of cannabidiol in consumer products24
The toxicity of lead on human neuroblastoma cells was alleviated by HUC-MSC-derived exosomes through miR-26a-5p/PTEN pathway24
Safety and toxicologic evaluation of Edible Pongamia Oil: A novel food ingredient24
Impact of food matrices on the characteristics and cellular toxicities of ingested nanoplastics in a simulated digestive tract24
RIFM fragrance ingredient safety assessment, 1-propanol, 2-methyl-3-[(1,7,7-trimethylbicyclo-[2.2.1]hept-2-yl)oxy]-, CAS Registry Number 128119-70-023
Bioactive extract of Morchella esculenta ameliorates cyclophosphamide-induced mitochondrial dysfunction and cardiotoxicity by modulating KEAP1/NRF2 and pro-inflammatory genes expression23
Update to RIFM fragrance ingredient safety assessment, acetaldehyde, diphenethyl acetal, CAS Registry Number 122-71-423
RIFM fragrance ingredient safety assessment, butyl salicylate, CAS Registry Number 2052-14-423
RIFM fragrance ingredient safety assessment, pyridine, 4-[1(4-,5 or 6)-methylbicyclo[2.2.1]hept-5-en-2-yl]-, CAS Registry Number 862079-91-223
Update to RIFM fragrance ingredient safety assessment, dimethyl succinate, CAS Registry Number 106-65-023
Update to RIFM fragrance ingredient safety assessment, benzyl formate, CAS Registry Number 104-57-423
Imatinib disturbs lysosomal function and morphology and impairs the activity of mTORC1 in human hepatocyte cell lines23
Acute ivermectin toxicity on skin and brain tissue of adult albino rats: Evaluation of the role of Flumazenil and Vitamin C as new treatment modalities23
Update to RIFM fragrance ingredient safety assessment, isoamyl hexanoate, CAS registry number 2198-61-023
RIFM fragrance ingredient safety assessment, 1-oxaspiro[4.5]deca-3,6-diene, 2,6,9,10-tetramethyl-, CAS Registry Number 71078-31-423
RIFM fragrance ingredient safety assessment, 3-hexanone, 5-mercapto-5-methyl-, CAS Registry Number 851768-51-923
RIFM fragrance ingredient safety assessment, d-8-p-menthene-1,2-epoxide, CAS Registry Number 1195-92-223
Vallaris solanacea induces mitochondrial mediated apoptosis in HL-60 human promyelocytic leukemia cells23
RIFM fragrance ingredient safety assessment, thymol, CAS Registry Number 89-83-823
Dermal repeated dose toxicity study of the anti-breast cancer drug Formestane cream in Bama minipig23
RIFM fragrance ingredient safety assessment, methyl sorbate, CAS Registry Number 689-89-423
An in vitro protocol to characterise the resistance of food proteins to intestinal digestion23
RIFM fragrance ingredient safety assessment, 2,3,5-trimethylpyrazine, CAS registry number 14667-55-122
RIFM fragrance ingredient safety assessment, isolongifolene oxide, CAS Registry Number 26619-69-222
RIFM fragrance ingredient safety assessment, cis-jasmone, CAS registry number 488-10-822
RIFM fragrance ingredient safety assessment, methyl 4(or 1)-isopropyl-1(or 4)-methylbicyclo[2.2.2]oct-5-ene-2-carboxylate, CAS Registry Number 68966-86-922
RIFM fragrance ingredient safety assessment, 11-oxahexadecanolide, CAS Registry Number 3391-83-122
Update to RIFM fragrance ingredient safety assessment, hexanoic acid, 4-methyl-, CAS registry number 1561-11-122
Maternal exposure to a glyphosate-based herbicide impairs placental development through endoplasmic reticulum stress in mice22
Update to RIFM fragrance ingredient safety assessment, β-caryophyllene alcohol, CAS registry number 472-97-922
RIFM fragrance ingredient safety assessment, cinnamyl butyrate, CAS Registry Number 103-61-722
RIFM fragrance ingredient safety assessment, sclareolide, CAS Registry Number 564-20-522
Cyanidin-3-O-glucoside and its metabolite protocatechuic acid ameliorate 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induced cytotoxicity in HepG2 cells by regulating apoptotic and Nrf2/p6222
RIFM fragrance ingredient safety assessment, benzoic acid, 2-hydroxy-5-methyl-, methyl ester, CAS Registry Number 22717-57-322
RIFM fragrance ingredient safety assessment, 3-phenylpropionaldehyde, CAS Registry Number 104-53-022
Enantioselective toxicity effect and mechanism of hexaconazole enantiomers to human breast cancer cells22
In vitro toxicological assessment of aerosols from indirectly heated tobacco products using a solvent-free extraction method22
Editorial Board22
RIFM fragrance ingredient safety assessment, 4-thujanol, CAS Registry Number 546-79-222
Thymoquinone induces oxidative stress-mediated apoptosis through downregulation of Jak2/STAT3 signaling pathway in human melanoma cells22
RIFM fragrance ingredient safety assessment, 3,3,5-trimethylcyclohexyl ethyl ether, CAS Registry Number 67583-77-122
Choice of experimental model determines translational impact: The link between bisphenol A and cardiotoxicity21
Chronic glucocorticoid exposure accelerates Aβ generation and neurotoxicity by activating calcium-mediated CN-NFAT1 signaling in hippocampal neurons in APP/PS1 mice21
A time-course study of microglial activation and dopaminergic neuron loss in the substantia nigra of mice with paraquat-induced Parkinson's disease21
Ultrasensitive electrochemical sensor for detection of rutin antioxidant by layered Ti3Al0.5Cu0.5C2 MAX phase21
High fructose-induced skeletal muscle insulin resistance could be alleviated by berberine via AMPD1 and ADSL21
RIFM fragrance ingredient safety assessment, methyl p-methylbenzoate, CAS Registry Number 99-75-221
Editorial Board21
RIFM fragrance ingredient safety assessment, α-pinene, CAS Registry Number 80-56-821
The Austrian children's biomonitoring survey 2020 Part B: Mycotoxins, phytotoxins, phytoestrogens and food processing contaminants21
Protective role of the dried white mulberry extract on the reproductive damage and fertility in rats treated with carmustine21
Potential exacerbation of polycystic ovary syndrome by saccharin sodium Via taste receptors in a letrozole rat model21
Bisphenol analogues inhibit human and rat 17β-hydroxysteroid dehydrogenase 1: 3D-quantitative structure-activity relationship (3D-QSAR) and in silico docking analysis21
Normolipidic diet containing deep-fried saturated and unsaturated fatty acids rich edible oils promotes metabolic dysregulation and inflammatory microenvironment in Wistar rats21
Tanshinones from Salvia miltiorrhiza inhibit Mycobacterium tuberculosis via disruption of the cell envelope surface and oxidative stress21
Potential underlying mechanisms of ethambutol induced optic neuropathy: Evidence from in vitro to clinical studies21
Investigation of eight cellulose nanomaterials’ impact on Differentiated Caco-2 monolayer integrity and cytotoxicity21
Exposure to short-, medium-, and long-chain chlorinated paraffins for infant via cow infant formula, goat infant formula and baby food21
Risk assessment of potentially toxic trace elements via consumption of dairy products sold in the city of Yerevan, Armenia21
Inhibition of acrylamide toxicity in vivo by arginine-glucose maillard reaction products20
Publisher's Note20
Mitochondrial damage precedes the changes of glutathione metabolism in CdCl2 treated neuronal SH-SY5Y cells20
"Mechanisms of PDC-Induced Testicular Toxicity: Oxidative Stress, Steroidogenic Suppression, and Modulation by ZnO-NP/TEO Synergy"20
RIFM fragrance ingredient safety assessment, menthol, CAS Registry Number 89-78-120
Review of the oral toxicity of cannabidiol (CBD)20
Pharmacokinetics and 28-day repeated-dose toxicity of enniatin B after oral administration in mice20
Atrazine-induced oxidative damage via modulating xenobiotic-sensing nuclear receptors and cytochrome P450 systems in cerebrum and antagonism of lycopene20
Editorial Board20
Strawberry tree honey in combination with 5-fluorouracil enhances chemosensitivity in human colon adenocarcinoma cells20
Carcinogenic and non-carcinogenic risks caused by rice contamination with heavy metals and their effect on the prevalence of cardiovascular disease (Using machine learning)20
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