Toxicology

Article	Citations
Oleanolic acid-3-glucoside, a synthetic oleanane-type saponin, ameliorates methylmercury-induced dysfunction of synaptic transmission in mice	253
Editorial Board	235
Roles of N6-methyladenosine in LncRNA changes and oxidative damage in cadmium-induced pancreatic β-cells	187
Investigating the cardiotoxicity of N-n-butyl haloperidol iodide: Inhibition mechanisms on hERG channels	141
Differential eigengene network analysis reveals benzo[a]pyrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin consensus regulatory network in human liver cell line HepG2	103
Comparison of modes of action between fish, cell and mitochondrial toxicity based on toxicity correlation, excess toxicity and QSAR for class-based compounds	90
Preconception exposure to dibutyl phthalate (DBP) impairs spermatogenesis by activating NF-κB/COX-2/RANKL signaling in Sertoli cells	67
Two thyroperoxidase-inhibiting chemicals induce shared transcriptional changes in hippocampus of developing rats	67
Exposure to a combination of MWCNTs and DBP causes splenic toxicity in mice	64
Corrigendum to “Maternal linuron exposure alters testicular development in male offspring rats at the whole genome level” [Toxicology 389 (2017) 13–20]	60
Peritubular myoid cells of the testis produce monocyte chemotactic protein 1 upon direct exposure to Mono-(2-Ethylhexyl) phthalate through the IL-1 signaling pathway	60
Exploring cardiac impact of oral nicotine exposure in a transplantable Neoplasm Mice Model: Insights from biochemical analysis, morphometry, and molecular docking: Chlorella vulgaris green algae suppo	59
Editorial Board Members	59
Activation of α7 nicotinic acetylcholine receptor augments nerve growth factor action on PCtrk cells	58
Corrigendum to “Effects of perinatal exposure to bisphenol A on induction of prostate cancer in Sprague Dawley rats by MNU and testosterone” [Toxicology 484 (2023) 153394]	55
Prediction of drug-induced mitochondrial dysfunction using succinate-cytochrome c reductase activity, QSAR and molecular docking	51
Machine learning classification of steatogenic compounds using toxicogenomics profiles	49
Deep Learning Algorithm Based on Molecular Fingerprint for Prediction of Drug‐Induced Liver Injury	48
MCLR-elicited hepatic fibrosis and carcinogenic gene expression changes persist in rats with diet-induced nonalcoholic steatohepatitis through a 4-week recovery period	47
Differential effects of mercury compounds on mutagenicity, genotoxicity and repair of UV-DNA damage	46
Synergism in actions of HBV with aflatoxin in cancer development	45
Hexafluoropropylene oxide homologues, the novel alternatives to PFOA, induce mitochondrial dysfunction and cytotoxicity in Leydig cells through disrupting SIRT1/PGC-1α signaling pathway	45
The novel polyfluoroalkyl benzenesulfonate OBS exposure induces cell cycle arrest and senescence of rat pituitary cell GH3 via the p53/p21/RB pathway	45
Comprehensive analysis based in silico study of alternative bisphenols – Environmental explanation of prostate cancer progression	44
Ferrostatin‑1 alleviates liver injury via decreasing ferroptosis following ricin toxin poisoning in rat	43

Comparative study on gene expression profiles in the liver of male neonatal mice prenatally exposed to PFOA and its alternative HFPO-DA	43
Uric acid accumulation in the kidney triggers mast cell degranulation and aggravates renal oxidative stress	42
Nutrient molecule corona: An update for nanomaterial-food component interactions	42
The formation of lamellar body-like structures may be a trigger of cetylpyridinium chloride-induced cell death and inflammatory response	41
MLKL triggers NLRP3 activation in sodium arsenite-induced myocardial necroinflammation	40
Dimethyl fumarate induces cardiac developmental toxicity in zebrafish via down-regulation of oxidative stress	40
IL-10-TG/TPO-T4 axis, the target of bis (2-ethylhexyl) tetrabromophthalate on thyroid function imbalance	39
A preliminary study of combined toxicity and underlying mechanisms of imidacloprid and cadmium coexposure using a multiomics integration approach	39
Per- and polyfluoroalkyl substances as potentiators of hepatotoxicity in an exposome framework: Current challenges of environmental toxicology	38
Novel flame retardants (NFRs) in e-waste: Environmental burdens, health implications, and recommendations for safety assessment and sustainable management	38
The effects of hexabromocyclododecane on the transcriptome and hepatic enzyme activity in three human HepaRG-based models	37
Edible vegetables grown in the vicinity of electronic wastes: A study of potential health risks and DNA damage in consumers	37
Corrigendum to “Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats” [Toxicology 449 (2021) 152665]	36
A mechanistic toxicology study to grasp the mechanics of zearalenone estrogenicity: Spotlighting aromatase and the effects of its genetic variability	35
Di-(2-ethylhexyl) phthalate induces prepubertal testicular injury through MAM-related mitochondrial calcium overload in Leydig and Sertoli cell apoptosis	34
Triclosan has a strong influence on the development of mouse preimplantation embryo via activating miR-134/Nanog axis	33
Establishment of a point of departure for CBD hepatotoxicity employing human HepaRG spheroids	33
Acrolein inhalation acutely affects the regulation of mitochondrial metabolism in rat lung	32
Neurotoxicity of Tris (1,3-dichloroisopropyl) phosphate in Caenorhabditis elegans	32
Gold nanoparticle intratesticular injections as a potential animal sterilization tool: Long-term reproductive and toxicological implications	32
Influence of aryl hydrocarbon receptor and sulfotransferase 1A1 on bisphenol AF-induced clastogenesis in human hepatoma cells	31
Necroptosis contributes to airborne particulate matter-induced ocular surface injury	31
The Cost Outcome Pathway framework: Integrating socio-economic impacts to Adverse Outcome Pathways for supporting policy makers	30
Chemical effects on neural network activity: Comparison of acute versus network formation exposure in microelectrode array assays	30
Lambda cyhalothrin and chlorantraniliprole caused biochemical, histological, and immunohistochemical alterations in male rabbit liver: Ameliorative effect of vitamins A, D, E, C mixture	30
Copper oxide nanoparticles disrupt lysosomal function and promote foam cell formation in RAW264.7 macrophages	30
Microplastics/nanoplastics and neurological health: An overview of neurological defects and mechanisms	29
High-throughput screening of respiratory hazards: Exploring lung surfactant inhibition with 20 benchmark chemicals	28
Organochlorine pesticides: occurrence, spatial distribution of residues, toxicity, and toxic mechanisms	28
The role of mouse and human peroxisome proliferator-activated receptor-α in modulating the hepatic effects of perfluorooctane sulfonate in mice	28
Legacy and alternative per- and polyfluoroalkyl substances (PFAS) alter the lipid profile of HepaRG cells	28
Predictive, integrative, and regulatory aspects of AI-driven computational toxicology – Highlights of the German Pharm-Tox Summit (GPTS) 2024	27
Predicting in vitro assays related to liver function using probabilistic machine learning	27
Editorial Board Members	27
Effects of ELF-PEMF exposure on spontaneous alternation, anxiety, motor co-ordination and locomotor activity of adult wistar rats and viability of C6 (Glial) cells in culture	26
Protection from benzene-induced immune dysfunction in mice	26
Corrigendum to “Inhibitory effects of parabens on human and rat 17β-hydroxysteroid dehydrogenase 1: Mechanisms of action and impact on hormone synthesis” Toxicology 506 (August) (2024) 153873	25
Increased TSLP and oxidative stress reflect airway epithelium injury upon cigarette smoke exposure. Is there a role for carbocysteine?	25
Toxic talk: pannexin1 channel communication as an emerging mechanism of toxicity	25
Immunosuppression characterized by increased Treg cell and IL-10 levels in benzene-induced hematopoietic toxicity mouse model	25
MLKL deficiency alleviates acute alcoholic liver injury via inhibition of NLRP3 inflammasome	25
GenX induces fibroinflammatory gene expression in primary human hepatocytes	24
Cytotoxicity and pro-inflammatory effect of polystyrene nano-plastic and micro-plastic on RAW264.7 cells	24
Fine particulate matter disrupts bile acid homeostasis in hepatocytes via binding to and activating farnesoid X receptor	24
Chronic consumption of food-additives lead to changes via microbiota gut-brain axis	24
OTSSP167 leads to follicular dysplasia and negatively affects oocyte quality in mice	24
Exposure to polystyrene nanoplastics promotes premature cellular senescence through mitochondrial ROS production and dysfunction in pre-differentiated skeletal myoblasts	24
Pb inhibited C2C12 myoblast differentiation by regulating HDAC2	23
NAM-based prediction of point-of-contact toxicity in the lung: A case example with 1,3-dichloropropene	23
Ferroptosis is involved in cisplatin sensitivity of the S3 segment of immortalized proximal tubule cells	23

ROS-mediated NRF2/p-ERK1/2 signaling-involved mitophagy contributes to macrophages activation induced by CdTe quantum dots	23
Nicotine stimulates IL-8 expression via ROS/NF-κB and ROS/MAPK/AP-1 axis in human gastric cancer cells	23
Corrigendum to “Chronic oral depleted uranium leads to reproductive damage in male rats through the ROS-hnRNP A2/B1-COX-2 signaling pathway” [Toxicology 449 (2021) 152666]	23
Assessing micro and nanoplastics toxicity using rodent models: Investigating potential mitochondrial implications	23
The effects of fumonisin B1 on intercellular communications and miRNA modulations: Non-genotoxic carcinogenesis mechanisms in human kidney cells	23
Benzyl butyl phthalate promotes ferroptosis in Sertoli cells via disrupting ceruloplasmin-mediated iron balance	23
Editorial Board Members	22
Genomic comparisons between hepatocarcinogenic and non-hepatocarcinogenic organophosphate insecticides in the mouse liver	22
N-isopropylbenzylamine, a methamphetamine mimics, produces toxicity via increasing nitric oxide in vitro	22
Immunotoxicity of 2-Acetyl-4-tetrahydroxybutylimidazole in BALB/c mice with different vitamin B6 nutritional statuses	22
Corrigendum to “Graphene quantum dots (GQDs) induce thigmotactic effect in zebrafish larvae via modulating key genes and metabolites related to synaptic plasticity” [Toxicology 487 (2023) 1–13]	22
A comprehensive review of the proline mimic azetidine-2-carboxylic acid (A2C)	22
PCB126 induced toxic actions on liver energy metabolism is mediated by AhR in rats	21
PM2.5 induces mitochondrial dysfunction via AHR-mediated cyp1a1 overexpression during zebrafish heart development	21
Environmental factors modulating protein conformations and their role in protein aggregation diseases	21
Protective effect of dental pulp stem cells' conditioned medium against cisplatin-induced testicular damage in rats	21
The mechanism of the neuroprotective effect of zinc against cadmium-induced behavioral impairments in male Wister rats: Focus on tryptophan degradation pathway, oxidative-inflammatory stress, and hist	21
The p,p’-DDE disturbs the M1 function without affecting the M2 phenotype nor unstimulated bone marrow-derived macrophages from BALB/c mice	21
Role of miR-145-5p/ CD40 in the inflammation and apoptosis of HUVECs induced by PM2.5	21
Hematological, cardiovascular and oxidative DNA damage markers associated with heavy metal exposure in electronic waste (e-waste) workers of Bangladesh	21
Endocrine toxicity of atrazine and its underlying mechanisms	20
Effects of methoxychlor on broiler gut microbiota and liver and its residue accumulation risk to human health	20
Immunotoxic effect and mechanisms of Fusarium mycotoxins on human immune cells: A focus on T cells and macrophages	20
Influence of polystyrene nanoparticles on the toxicity of tetrabromobisphenol A in human intestinal cell lines	20
Editorial Board	20
Editorial Board	20
Three-dimensional cultured ampullae from rats as a screening tool for vestibulotoxicity: Proof of concept using styrene	20
In vitro toxicological evaluation of glo menthol and non-menthol heated tobacco products	20
Exposure to TCBPA stimulates the growth of arterial smooth muscle cells through the activation of the ROS/NF-κB/NLRP3 signaling pathway	20
Interaction and toxicity of ingested nanoparticles on the intestinal barrier	20
Kupffer cells play a crucial role in monocrotaline-induced liver injury by producing TNF-α	20
Extracellular histones cause intestinal epithelium injury and disrupt its barrier function in vitro and in vivo	19
A Benchmark analysis of acrylamide-derived DNA adducts in rat hepatocytes in culture measured by a new, highly sensitive method	19
Mechanisms and treatment strategies of organophosphate pesticide induced neurotoxicity in humans: A critical appraisal	19
Bisphenol A induced neuronal apoptosis and enhanced autophagy in vitro through Nrf2/HO-1 and Akt/mTOR pathways	19
Maternal urban particulate matter exposure and signaling pathways in fetal brains and neurobehavioral development in offspring	19
Gestational exposure to BPA alters the expression of glucose and lipid metabolic mediators in the placenta: Role in programming offspring for obesity	19
Mitochondria damage and ferroptosis involved in Ni-induced hepatotoxicity in mice	19
Retraction notice to “Arsenic-induced mitochondrial instability leading to programmed cell death in the exposed individuals" [Toxicology 246 (2008) 101–111]	19
Neonatal exposure of bisphenol A led to increased lipolysis of visceral adipose tissue in adult rats with DNA hypomethylation of Atgl being one of the possible underlying mechanisms	19
Multi-omics analysis reveals BPF exposure causes hepatic glucose and lipid metabolism disorder in rats by disrupting energy homeostasis	19
Exposure to volatile organic compounds induces cardiovascular toxicity that may involve DNA methylation	19
Editorial Board	18
Ameliorative effects of the phytochemicals in dates (Phoenix dactylifera) against the toxicological changes induced by fipronil in male albino rats	18
A computational study on the biotransformation of alkenylbenzenes by a selection of CYPs: Reflections on their possible bioactivation	18
Evaluation of mutagenic, cytotoxic, mitochondrial dysfunction, apoptotic activity, and acute toxicity of ethanolic extract of Cissus quadrangularis	18
Silica nanoparticles induce pulmonary damage in rats via VEGFC/D–VEGFR3 signaling-mediated lymphangiogenesis and remodeling	18
Dynamic analysis of intrahepatic T cells reveals a unique group of restorative Cxcr3 tissue-resident CD4 T cells in acute liver injury	18
Hepatic lipid metabolism disorders and immunotoxicity induced by cysteamine in early developmental stages of zebrafish	18
Editorial Board Members	18
Polystyrene microplastics aggravate acute pancreatitis in mice	18
Effect of the extra-nuclear cation on the cytotoxicity and mechanism of action of pyridine-2,6-dicarboxylate Ga(III) complexes	18
A microRNA signature for valproate-induced steatosis in human hepatocytes and its application to predict fatty liver in paediatric epileptic patients on valproate therapy	18
Considerations for future quantitative structure-activity relationship (QSAR) modelling for heavy metals – A case study of mercury	18
Recombinant Klotho alleviates vancomycin-induced acute kidney injury by upregulating anti-oxidative capacity via JAK2/STAT3/GPx3 axis	18
RNA-Seq approach to investigate the effects of melatonin on bone marrow-derived dendritic cells from dextran sodium sulfate-induced colitis mice	18
Ochratoxin A stimulates release of IL-1β, IL–18 and CXCL8 from cultured human microglia	17
Tetrabromobisphenol S (TBBPS) exposure causes gastric cell senescence and inflammation by inducing iron overload	17
The effects and mechanism of LncRNA NORAD on doxorubicin-induced cardiotoxicity	17
Exposure to organophosphate flame retardants and phthalates alters neuronal activity and network development	17
Dihydrotestosterone induces reactive oxygen species accumulation and mitochondrial fission leading to apoptosis of granulosa cells	17
Autophagy alleviates hippocampal neuroinflammation by inhibiting the NLRP3 inflammasome in a juvenile rat model exposed particulate matter	17
Developments in the field of intestinal toxicity and signaling pathways associated with rodent exposure to micro(nano)plastics	17
CYP2E1 mediated deoxynivalenol-induced hepatocyte toxicity by regulating ferroptosis	17
The variability in CYP3A4 activity determines the metabolic kinetic characteristics of ketamine	17
Fluoride induced metabolic disorder of endothelial cells	17
Comparative evaluation of mutagenic, genotoxic, cytotoxic, and antimicrobial effects of flavour and fragrance aldehydes, ketones, oximes, and oxime ethers	17
Lycium barbarum polysaccharides attenuate nonylphenol and octylphenol-induced oxidative stress and neurotransmitter disorders in PC-12 cells	17
Editorial Board Members	16
Arsenic induces metabolome remodeling in mature human adipocytes	16
Comprehensive analysis of the impact of emerging flame retardants on prostate cancer progression: The potential molecular mechanisms and immune infiltration landscape	16
Knock-down of FOXO3, GATA2, NFE2L2 and AHR promotes doxorubicin-induced cardiotoxicity in human cardiomyocytes	16
Chronic D-galactose administration induces natural aging characteristics, in rat’s brain and heart	16
Role of myo-inositol in acute kidney injury induced by cisplatin	16
Investigation of a broad diversity of nanoparticles, including their processes, as well as toxicity testing in diverse organs and systems	16
Bmi1 signaling maintains the plasticity of airway epithelial progenitors in response to persistent silica exposures	16
Polystyrene microplastics induced oxidative stress, inflammation and necroptosis via NF-κB and RIP1/RIP3/MLKL pathway in chicken kidney	16
Genotoxicity assessment of 1,4-anhydro-4-seleno-D-talitol (SeTal) in human liver HepG2 and HepaRG cells	16
Effect of persistent organic pollutants in patients with ischemic stroke and all stroke: A systematic review and meta-analysis	16
Ophiopogonin D′-induced mitophagy and mitochondrial damage are associated with dysregulation of the PINK1/Parkin signaling pathway in AC16 cells	16

Embryonic exposure to GenX causes reproductive toxicity by disrupting the formation of the blood-testis barrier in mouse offspring	16
Hematological consequences of polyethylene microplastics toxicity in male rats: Oxidative stress, genetic, and epigenetic links	16
Upregulation of postsynaptic cAMP/PKA/CREB signaling alleviates copper(Ⅱ)-induced oxidative stress and pyroptosis in MN9D cells	15
Health impacts of PM2.5 emissions from brake pad wear: A comprehensive study on pulmonary, metabolic, and microbiota alterations	15
O-alkyl and o-benzyl hesperetin derivative-1L attenuates inflammation and protects against alcoholic liver injury via inhibition of BRD2-NF-κB signaling pathway	15
Evaluation of toxicological effects of bisphenol S with an in vitro human bone marrow mesenchymal stem cell: Implications for bone health	15
Teratological, neurochemical and histomorphic changes in the limbic areas of F1 mice progeny due to co-parental polystyrene nanoplastic exposure	15
Neurotoxic effects and cognitive decline induced by Aniline Blue dye in an in-vivo zebrafish model	15
The impact of legacy and novel perfluoroalkyl substances on human cytochrome P450: An in vitro study on the inhibitory potential and underlying mechanisms	15
Ex vivo exposure to p,p'-DDE decreases human macrophage polarization to the M1 phenotype	15
6PPD induces apoptosis and autophagy in SH-SY5Y cells via ROS-mediated PI3K/AKT/mTOR pathway: In vitro and in silico approaches	15
Graphene quantum dots disturbed the energy homeostasis by influencing lipid metabolism of macrophages	15
Association of endocrine disrupting chemicals levels in serum, environmental risk factors, and hepatic function among 5- to 14-year-old children	15
Differential susceptibility of Leydig and Sertoli cells to bisphenol A	15
Sintilimab combined with acetaminophen aggravates liver injury through apoptotic and disturbed bile acid pathways	15
A mechanistically-anchored and human stem cell-based in vitro test battery for assessing liver steatogenic potential of chemicals	15
Notch1-Dependent Hippocampal Apoptosis is Associated with Monocrotaline-Induced Anxiety-Like Behavior	15
Effects of perfluorooctanoic acid (PFOA) on gene expression profiles via nuclear receptors in HepaRG cells: Comparative study with in vitro transactivation assays	15
Acute cytotoxicity of mineral fibres observed by time-lapse video microscopy	15
Mechanisms involved in pro-inflammatory responses to traffic-derived particulate matter (PM) in THP-1 macrophages compared to HBEC3-KT bronchial epithelial cells	14
A metabolomic approach to study triptolide-induced ovarian damage in rats	14
Long-term exposure to polystyrene microplastics reduces macrophages and affects the microbiota–gut–brain axis in mice	14
AFB1 consolidates HBV harm to induce liver injury and carcinogenic risk by inactivating FTCD-AS1-PXR-MASP1 axis	14
Di-n-butyl phthalate regulates vascular smooth muscle cells phenotypic switching by MiR-139–5p-MYOCD pathways	14
Editorial Board Members	14
Sodium arsenite accelerates D-galactose-induced aging in the testis of the rat: Evidence for mitochondrial oxidative damage, NF-kB, JNK, and apoptosis pathways	14
Molecular mechanisms of developmental toxicity induced by BBP in zebrafish embryos	14
Environmentally relevant concentrations of individual per- and polyfluoroalkyl substances (PFAS) and a PFAS mixture impact proliferation, migration, and gene transcription in a human myometrial cell l	14
Obituary for Karl Joachim Netter	14
Ripretinib induced skeletal muscle toxicity through mitochondrial impairment in C2C12 myotubes	14
Cadmium promotes hyaluronan synthesis by inducing hyaluronan synthase 3 expression in cultured vascular endothelial cells via the c-Jun N-terminal kinase–c-Jun pathway	14
Editorial Board Members	14
Loperamide induces excessive accumulation of bile acids in the liver of mice with different diets	13
Virtual display of targets: A new level to rise the current understanding of ochratoxin A toxicity from a molecular standpoint	13
Dynamics and mechanisms of bioaccumulation and elimination of nonylphenol in zebrafish	13
Toxicity evaluation of particles formed during 3D-printing: Cytotoxic, genotoxic, and inflammatory response in lung and macrophage models	13
Graphene quantum dots (GQDs) induce thigmotactic effect in zebrafish larvae via modulating key genes and metabolites related to synaptic plasticity	13
Per- and poly-fluoroalkyl substances (PFAS) and female reproductive outcomes: PFAS elimination, endocrine-mediated effects, and disease	13
Utilization of the CometChip assay for detecting PAH-induced DNA bulky adducts in a 3D primary human bronchial epithelial cell model	13
Cadmium induces spontaneous abortion by impairing endometrial stromal cell decidualization	13
The crucial involvement of gamma-Mangostin and CYP1B1 in the mechanism underlying the toxicity caused by cigarette smoke extract: In silico and in vitro insights	13
BPA exposure aggravates necroptosis of myocardial tissue in selenium deficient broilers through NO-dependent endoplasmic reticulum stress	13
Association between occupational lead exposure and immunotoxicity markers: A systematic review and meta-analysis	13
InterDIA: Interpretable prediction of drug-induced autoimmunity through ensemble machine learning approaches	13
Sorafenib is an antagonist of the aryl hydrocarbon receptor	13
Lycopene alleviates Deoxynivalenol-induced toxicity in Porcine intestinal epithelial cells by mediating mitochondrial function	13
Effect of modified citrus pectin on galectin-3 inhibition in cisplatin-induced cardiac and renal toxicity	13
In vitro test battery for testing molecular initiating events in chemical-induced cholestasis	13
Long-term exposure to arsenic in drinking water leads to myocardial damage by oxidative stress and reduction in NO	13
Increasing confidence in new approach methodologies for inhalation risk assessment with multiple end point assays using 5-day repeated exposure to 1,3-dichloropropene	13
Editorial Board Members	12
Editorial Board	12
Cellular targets of mefloquine	12
Effects of endocrine disrupting chemicals on the expression of RACK1 and LPS-induced THP-1 cell activation	12
Repeat-dose and local tolerance toxicity of SARS-CoV-2 FINLAY-FR-02 vaccine candidate in Sprague Dawley rats	12
‘Corrigendum to: “Bayesian benchmark dose analysis for inorganic arsenic in drinking water associated with bladder and lung cancer using epidemiological data” [Toxicology 455 (2021) 152752]’	12
Prenatal exposure to dibutyl phthalate contributes to erectile dysfunction in offspring male rats by activating the RhoA/ROCK signalling pathway	12
Exploring the dynamics of the ABCB1 membrane transporter P-glycoprotein in the presence of ATP and active/non-active compounds through molecular dynamics simulations	12
Investigating the functional role of BUB1B in aflatoxin B1-associated hepatocarcinogenesis	12
Neurodevelopment effects of early life bisphenol-A exposure on visual memory: Insights into recovery dynamics	12
MCF-7 cell - derived exosomes were involved in protecting source cells from the damage caused by tributyltin chloride via transport function	12
Tobacco smoking exposure-mediated ELAVL1 regulates bladder cancer cell senescence via autophagy activation	12
Polystyrene microplastics trigger colonic inflammation in rats via the TLR4/NF-κB/COX-2 pathway and modulation of intestinal microbiota	12
Chlorpyrifos impairs sperm parameters and number of Sertoli and Leydig cells in rats after exposure during the peripubertal period	11
ToxProfiler: A novel human-based reporter assay for in vitro chemical safety assessment	11
Occurrence and ecotoxicological impacts of polybrominated diphenyl ethers (PBDEs) in electronic waste (e-waste) in Africa: Options for sustainable and eco-friendly management strategies	11
Glutathione attenuates diesel exhaust-induced lung epithelial injury via NF-κB/Nrf2/GPX4-mediated ferroptosis	11
Evaluating combined effects of chronic, low-dose exposures of cadmium (CLEC) and hyperglycemia on insulin signaling dysfunction in a hepatocellular model	11
Clinical and experimental research progress on neurotoxicity of sulfur mustard and its possible mechanisms	11
Generation & characterization of expandable human liver sinusoidal endothelial cells and their application to assess hepatotoxicity in an advanced in vitro liver model	11
Developmental toxicity of fenbuconazole in zebrafish: Effects on mitochondrial respiration and locomotor behavior	11
Multi-omics analyses of serum metabolome, urine metabolome and gut microbiome reveal dysregulated glycerophospholipid metabolism in subacute cadmium-exposed wistar rats	11
Identification of circRNA expression profiles and the potential role of hsa_circ_0006916 in silicosis and pulmonary fibrosis	11
Alternative animal models in predictive toxicology	11
Geniposide suppresses thermogenesis via regulating PKA catalytic subunit in adipocytes	11
Mirabegron alleviates acetic acid-induced colitis in rats: Role of adiponectin and GSTM1/GSH detoxification pathway	11
Prediction of polybrominated diphenyl ethers (PBDEs) as potential substrates of various human CYP enzymes and laboratory test of BDE-99 for its metabolism-activated mutagenicity	11
Enantiospecific hepatotoxicity of usnic acid in vitro, and the attempt to modify the toxic effect	11
Establishing allometric relationships between microsomal protein and cytochrome P450 content with body weight in vertebrate species	11
Effects of radon exposure on gut microbiota and its metabolites short-chain fatty acids in mice	11
Metformin inhibits OCTN1- and OCTN2-mediated hepatic accumulation of doxorubicin and alleviates its hepatotoxicity in mice	11
Oxidative metabolism in the cardiorespiratory system after an acute exposure to nickel-doped nanoparticles in mice	11
Chronic low-level exposure to Pb, Hg, and Cd mixture triggers brain premature aging in rat	11
Close association between the synergistic toxicity of zearalenone-deoxynivalenol combination and microRNA221-mediated PTEN/PI3K/AKT signaling in HepG2 cells	11
Regulating of LncRNA2264/miR-20b-5p/IL17RD axis on hydrogen sulfide exposure-induced inflammation in broiler thymus by activating MYD88/NF-κB pathway	11
Effect of monosultap on notochord development in zebrafish (Danio rerio) embryos	11
Bioinformatics identification of shared signaling pathways and core targets linking Benzo[a]pyrene exposure to HCC progression	11
Prepubertal exposure to gadolinium-based contrast agents impairs sperm quality and elevates oxidative stress in adult rats	11
Resveratrol protected acrolein-induced ferroptosis and insulin secretion dysfunction via ER-stress- related PERK pathway in MIN6 cells	11
Antimony induces mitochondria-dependent and ER stress-triggered apoptosis via the oxidative stress-activated JNK signaling pathway in pancreatic islet β-cells	11
Advances in Antituberculosis Drug-induced Liver Injury: Molecular Mechanisms, Genetic Insights, and Emerging Animal-Free Prediction Models	11