Biochimie

Article	Citations
Advanced profiling and structural analysis of anencephaly gangliosides by ion mobility tandem mass spectrometry	148
Macrolactin a is an inhibitor of protein biosynthesis in bacteria	77
The modulation of low molecular weight sulfur compounds levels in visceral adipose tissue of TLR2-deficient mice on a high-fat diet	46
Hijacking a real time detection thermocycler for enzymology: Improvement of a fluorescent bulk assay monitoring helicase activity	42
Optimized high-yield expression of envelope glycoprotein domain III from dengue virus serotypes 1 to 4	42
Achatina fulica haemocyanin-derived peptides as novel antimicrobial agents	41
Diabetes mellitus and melatonin: Where are we?	40
Functions of long non-coding RNA ROR in patient-derived glioblastoma cells	39
Retinoic acid restores the levels of cellular cholesterol in Leishmania donovani infected macrophages by increasing npc1 and npc2 expressions	39
Death and the desaturase: Implication of Stearoyl-CoA desaturase-1 in the mechanisms of cell stress, apoptosis, and ferroptosis	38
Neutrophils and purinergic signaling: partners in the crime against Leishmania parasites?	37
Retraction notice to “Effects of geniposide on hepatocytes undergoing epithelial-mesenchymal transition in hepatic fibrosis by targeting TGFβ/Smad and ERK-MAPK signaling pathways” [Biochimie 113 (2015	36
Retraction notice to “MiR-650 regulates the proliferation, migration and invasion of human oral cancer by targeting Growth factor independent 1 (Gfi1)” [Biochimie 156 (2018) 69–78]	34
Retraction notice to “Betulinic acid downregulates expression of oxidative stress-induced lipoprotein lipase via PKC/ERK/c-Fos pathways in RAW264.7 macrophages” [Biochimie 119C (2015) 192–203]	34
Tau R2 and R3 are essential regions for tau aggregation, seeding and propagation	34
Advances in fluorescence microscopy can reveal important new aspects of tissue regeneration	33
Naked mole-rat hyaluronan	32
In silico activity and effect of synthetic chalcones on Candida albicans and Candida tropicalis biofilms	29
Loops constructing the substrate-binding site controlled the catalytic efficiency of Thermus thermophilus SG0.5JP17-16 laccase	29
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Unraveling the impact of the p.R107L mutation on the structure and function of human αB-Crystallin: Implications for cataract formation	28
Serum fatty acid profiling in patients with SDHx mutations: New advances on cellular metabolism in SDH deficiency	28
Characterization of SLA RNA promoter from dengue virus and its interaction with the viral non-structural NS5 protein	28
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Deciphering the Akt1-HuD interaction in HuD-mediated neuronal differentiation	26

Reviewer Acknowledgement	26
Lipids play music at the cellular membrane: From membranes dynamics to signaling via lipid mediators, vesicles and lipid droplets	26
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Reviewer Acknowledgement	25
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The non-Newtonian behavior of detergents during concentration is increased by macromolecules, in trans, and results in their over-concentration	22
Dual-targeted anti-CMV/anti-HIV-1 heterodimers	21
Identification of new Omega-3 very long chain poly-unsaturated fatty acids in meibomian gland secretions	21
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Blood derived extracellular vesicles as regenerative medicine therapeutics	20
The key role of aquaporins in animals and plants	20
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Thermoneutral housing does not rescue olanzapine-induced trabecular bone loss in C57BL/6J female mice	19
DNA binding site kinetics of a large antiviral polyamide	19
Conservation and over-representation of G-quadruplex sequences in regulatory regions of mitochondrial DNA across distinct taxonomic sub-groups	19
Molecular etiology of defective nuclear and mitochondrial ribosome biogenesis: Clinical phenotypes and therapy	19
The chemical mechanisms of the enzymes in the branched-chain amino acids biosynthetic pathway and their applications	19
Melatonin as an adjuvant treatment modality with doxorubicin	18
A mass spectrometric approach to study the interaction of amyloid β peptides with human α-2-macroglobulin	18
Dynamics prediction of emerging notable spike protein mutations in SARS-CoV-2 implies a need for updated vaccines	18
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Revealing O-acetylhomoserine sulfhydrylase involved in direct sulfhydrylation pathway in Clostridium tetani	17
Essential sufficiency of zinc, ω-3 polyunsaturated fatty acids, vitamin D and magnesium for prevention and treatment of COVID-19, diabetes, cardiovascular diseases, lung diseases and cancer	17
The pro-inflammatory responses of innate immune cells to Leishmania RNA virus 2-infected L. major support the survival and proliferation of the parasites	17
Hematopoietically-expressed homeobox protein HHEX regulates adipogenesis in preadipocytes	17
The role of the gut microbial metabolism of sterols and bile acids in human health	17
Cathepsin D inhibition during neuronal differentiation selectively affects individual proteins instead of overall protein turnover	16
Epithelium-specific ETS transcription factor-1 regulates NANOG expression and inhibits NANOG-induced proliferation of human embryonic carcinoma cells	16
Myelin basic protein antagonizes the SARS-CoV-2 protein ORF3a-induced autophagy inhibition	16
Assessment of membrane labelling mechanisms with exogenous fatty acids and detergents in bacteria	16
The knockdown efficiency of telomere associated genes with specific methodology in a zebrafish cell line	16
Evaluating the cytotoxicity mechanism of the cell-penetrating peptide TP10 on Jurkat cells	16
Potential of TSPO radioligands: Bridging brain tumor diagnostics to the peripheries	16
Characterization of the Arabidopsis thaliana chromatin remodeler DEK3 for its interaction with histones and DNA	16
Molecular and cellular outcomes of quercetin actions on healthy and tumor osteoblasts	15
Editorial: Regeneration in Health and Disease	15
The current state of amyloidosis therapeutics and the potential role of fluorine in their treatment	15
Methodologies and tools to shed light on erythrophagocytosis	15
Molecular and cellular mechanisms of melatonin in breast cancer	15
Cryptic inhibitory regions nearby activation domains	15
Aβ peptides stabilize GPCRs in inactive form and trigger inverse agonism in Alzheimer's disease	15
Decreased cortical Nrf2 gene expression in autism and its relationship to thiol and cobalamin status	15
Human microbial dysbiosis as driver of gynecological malignancies	15
Circadian rhythmicity of the thioredoxin system in cultured murine peritoneal macrophages	15
Disruption of mitochondrial bioenergetics, calcium retention capacity and cell viability caused by D-2-hydroxyglutaric acid in the heart	15
Mycobacterium tuberculosis and its secreted tyrosine phosphatases	14
Emerging therapeutic roles of small heat shock protein-derived mini-chaperones and their delivery strategies	14
Body, ambient and felt temperature: An attempt to resolve a human and mice dilemma	14

TolC-AcrA complex formation monitored by time dependent single-channel electrophysiology	14
Multimodal plasma metabolomics and lipidomics in elucidating metabolic perturbations in tuberculosis patients with concurrent type 2 diabetes	14
Establishment of fibroblast and myofibroblast phenotypes for use in in vitro co-culture models	14
Structural insights into the evolution of late steps of translation initiation in the three domains of life	13
Identification of a survival associated gene trio in chemical induced breast cancer	13
Does housing temperature influence glucose regulation and muscle-fat crosstalk in mice?	13
Evaluation of microRNA variant maturation prior to genome edition	13
In vitro and in silico characterization of a novel glutamate carboxypeptidase from Cohnella sp. A01	13
Phytoestrogens decorated nanocapsules for therapeutic methionine γ-lyase targeted delivery	13
A Malassezia pseudoprotease dominates the secreted hydrolase landscape and is a potential allergen on skin	12
N-terminal processing by dipeptidyl peptidase 9: Cut and Go!	12
The copper P-type ATPase CtpA is involved in the response of Mycobacterium tuberculosis to redox stress	12
Elucidating the pivotal role of TSPO in porphyrin-related cellular processes, in Bacillus cereus	12
Central nervous system pathways targeted by amylin in the regulation of food intake	12
Enzyme dysfunction at atomic resolution: Disease-associated variants of human phosphoglucomutase-1	12
The molecular crosstalk of the hippo cascade in breast cancer: A potential central susceptibility	12
Leishmania donovani mevalonate kinase regulates host actin for inducing phagocytosis	12
Isolation and characterization of a lectin-like chitinase from the hepatopancreas of freshwater prawn, Macrobrachium rosenbergii	12
The ‘Not-So-Famous Five’ in tumorigenesis: tRNAs, tRNA fragments, and tRNA epitranscriptome in concert with AARSs and AIMPs	12
New transaminase from Odontosyllis undecimdonta the first potential enzyme of the luciferin biosynthesis pathway	12
Impact of missense mutations in the ALDH7A1 gene on enzyme structure and catalytic function	12
Human DNA ligases I and IIIα as determinants of accuracy and efficiency of base excision DNA repair	12
A U2 snRNP-specific protein, U2A′, is involved in stress response and drug resistance in Cryptococcus deneoformans	12
Potential elevation of exopeptidase activity of Glu-specific endopeptidase I/GluV8 mediated by hydrophobic P1′-position amino acid residue	12
Unveiling the mechanism of hesperidin-induced LdTopI-mediated cell death pathway in protozoan parasite Leishmania donovani	12
Established and emerging players in phospholipid scrambling: A structural perspective	12
Aquaporins with lactate/lactic acid permeability at physiological pH conditions	12
Knockdown of the mRNA encoding the ribosomal protein eL38 in mammalian cells causes a substantial reorganization of genomic transcription	11
Functional analysis of Lsm protein under multiple stress conditions in the extreme haloarchaeon Haloferax mediterranei	11
Antimicrobial nano-assemblies of tryptocidine C, a tryptophan-rich cyclic decapeptide, from ethanolic solutions	11
Enhanced structure/function of mTSPO translocator in lipid:surfactant mixed micelles	11
Possible cancer-causing capacity of COVID-19: Is SARS-CoV-2 an oncogenic agent?	11
Intraovarian condensed platelet cytokines for infertility and menopause—Mirage or miracle?	11
DNA cleavage mechanism by metal complexes of Cu(II), Zn(II) and VO(IV) with a schiff-base ligand	11
Cellular binding and uptake of fluorescent glucose analogs 2-NBDG and 6-NBDG occurs independent of membrane glucose transporters	11
A meal rich in palm oil or butter modifies the sphingolipid profile of postprandial triglyceride-rich lipoproteins from type 2 diabetic women	11
Proteomics of the haemolymph of the terrestrial crustacean Porcellio scaber reveals components of its innate immunity under baseline conditions	11
History of how viruses can fight cancer: From the miraculous healings to the approval of oncolytic viruses	11
NMS-873 functions as a dual inhibitor of mitochondrial oxidative phosphorylation	11
Pancreatic islet cells disarray, apoptosis, and proliferation in obese mice. The role of Semaglutide treatment	11
The mitochondrial translocator protein (TSPO) in Alzheimer's disease: Therapeutic and immunomodulatory functions	11
Role of mitochondrial calcium in hypochlorite induced oxidative damage of cells	11
Unlocking the enigma of phenotypic drug tolerance: Mechanisms and emerging therapeutic strategies	11
Viral nanoparticles: Current advances in design and development	10
Deciphering the substrate specificity of housekeeping sortase A and pilus-specific sortase C of probiotic bacterium Lactococcus lactis	10
Loxosceles amazonica Brown Spider venom: Insights into enzymatic activities, immunorecognition, and novel phospholipase D isoforms	10
Zwitterionic fluorinated detergents: From design to membrane protein applications	10
Daidzein-directed methionine γ-lyase in enzyme prodrug therapy against breast cancer	10
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Unveiling overlooked pathways: The uric acid catabolism genes in the human genome	10
Lipid droplets degradation mechanisms from microalgae to mammals, a comparative overview	10
Ex vivo tolerization and M2 polarization of macrophages dampens both pro- and anti-inflammatory cytokine production in response to diabetic wound fluid stimulation	10
Glycolysis as key regulatory step in FSH-induced rat Sertoli cell proliferation: Role of the mTORC1 pathway	10
CD38/NAD+ glycohydrolase and associated antigens in chronic lymphocytic leukaemia: From interconnected signalling pathways to therapeutic strategies	10
Glial overexpression of Tspo extends lifespan and protects against frataxin deficiency in Drosophila	10
Shift in phospholipid and fatty acid contents accompanies brain myelination	10
Oncostatic activities of melatonin: Roles in cell cycle, apoptosis, and autophagy	10
A high-fat/high-cholesterol diet, but not high-cholesterol alone, increases free cholesterol and apoE-rich HDL serum levels in rats and upregulates hepatic ABCA1 expression	10
Biomembrane lipids: When physics and chemistry join to shape biological activity	9
Small molecule chaperones facilitate the folding of RNA G-quadruplexes	9
The structural and molecular biology of type IV galactosemia	9
Syndecan-1 and -4 influence Wnt signaling and cell migration in human breast cancers	9
Neuroprotectin D1, a lipid anti-inflammatory mediator, in patients with intracerebral hemorrhage	9
Rapid detection and imaging of methylglyoxal in plant tissues by the near-infrared fluorescent probe SWJT-2	9
Molecular explorations of the Leishmania donovani 6-phosphogluconolactonase enzyme, a key player in the pentose phosphate pathway	9
Involvement of aquaglyceroporins in energy metabolism in health and disease	9
Enhancing Amplification Efficiency and Reducing Molecular Diagnostic Reaction Time Through Rational Design of T4 gp32 Variants in Recombinase Polymerase Amplification	9
Oxidative distress in aging and age-related diseases: Spatiotemporal dysregulation of protein oxidation and degradation	9
Cell cycle and mitosis progression during ZIKA virus infection: The viral non-structural protein NS5 as a master regulator of the APC/cyclosome?	9
Specificity of lipid transfer proteins: An in vitro story	9
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CRISPR genotyping methods: Tracing the evolution from spoligotyping to machine learning	9
An update on inflammation in uveal melanoma	9
Leishmania (Viannia) braziliensis Thor strain and subpopulations Thor03, Thor10, and Thor22 have differences in the surface membrane proteases activity profile	9
DNA damage-induced senescence is associated with metabolomic reprogramming in breast cancer cells	9
Translocator protein (TSPO), still an enigmatic transmembrane protein: From structures to functions	9
The cysteine protease legumain decreases glucose metabolism and enhances fatty acid uptake in human myotubes	9
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Characterizing ligand-induced conformational changes in clinically relevant galectin-1 by HN/H2O (D2O) exchange	8
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Metabolic effects of combined glucagon receptor antagonism and glucagon-like peptide-1 receptor agonism in high fat fed mice	8
The rise of RNA: From fundamental research to therapeutic applications	8
Bring the heat: Thermal stress, metabolic plasticity, and considerations for biomedical research	8
Cloning and characterization of glycogen branching and debranching enzymes from the parasitic protist Trichomonas vaginalis	8
Exosomes derived from mesenchymal stem cells: A promising cell-free therapeutic tool for cutaneous wound healing	8
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MotSASi: Functional short linear motifs (SLiMs) prediction based on genomic single nucleotide variants and structural data	8
The emerging functions of mini zinc finger (MIF) microproteins in seed plants: A minireview	8
Influence of the aquatic environment and 1α,25(OH)2 vitamin D3 on calcium influx in the intestine of adult zebrafish	8
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Pyridoxal kinase gene deletion leads to impaired growth, deranged redox metabolism and cell cycle arrest in Leishmania donovani	8
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At the outer part of the active site in Trypanosoma cruzi glucokinase: The role of phenylalanine 337	8
G·U base pairing motifs in long non-coding RNAs	8
Creatine ameliorates high-fat diet-induced obesity by regulation of lipolysis and lipophagy in brown adipose tissue and liver	7
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Is the small heat shock protein HSPB7 (cvHsp) a genuine actin-binding protein?	7
Role of human group IIA secreted phospholipase A2 in malaria pathophysiology: Insights from a transgenic mouse model	7
Template requirements of Zika RNA polymerase during in vitro RNA synthesis from the 3′-end of virus minus-strand RNA	7
Kinetic and pharmacokinetic characteristics of therapeutic methinoninе γ-lyase encapsulated in polyion complex vesicles	7
First functional and proteomic analysis of Bothrops asper snake venom from Gorgona Island - Colombia, and its comparative characterization with two Colombian Southwest ecoregions	7
HIV-1 Tat: An update on transcriptional and non-transcriptional functions	7
Structural and mechanistic insights into the substrate specificity and hydrolysis of GH31 α-N-acetylgalactosaminidase	7
The role of Cannabidiol and tetrahydrocannabivarin to overcome doxorubicin resistance in MDA-MB-231 xenografts in athymic nude mice	7
Crosstalk between protein misfolding and endoplasmic reticulum stress during ageing and their role in age-related disorders	7
Editorial of the special issue “Tailored lipids: From synthesis to specific biological functions”	7
Characterization of novel gliotoxin biosynthesis-related genes from deep-sea-derived fungus Geosmithia pallida FS140	7
Brown/Beige adipose tissues and the emerging role of their secretory factors in improving metabolic health: The batokines	7
Thiolatocobalamins repair the activity of pathogenic variants of the human cobalamin processing enzyme CblC	7
Structural and thermodynamic analyses of human TMED1 (p24γ1) Golgi dynamics	7
Antioxidant cytochrome c-like activity of para-Mn(III)TMPyP	7
Odd-chain fatty acids as novel histone deacetylase 6 (HDAC6) inhibitors	7
Inhibition of soluble epoxide hydrolase as a therapeutic approach for blood-brain barrier dysfunction	7
Syndecan-4 regulates the HER2-positive breast cancer cell proliferation cells via CK19/AKT signalling	7
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Adipokines in obesity and metabolic-related-diseases	7
Modeling G4s in chromatin context confirms partial nucleosome exclusion and reveals nucleosome-disrupting effects of the least selective G4 ligands	7
Biochemical characterization of a unique DNA polymerase A from the extreme radioresistant organism Deinococcus radiodurans	7
Experimental models of lipid overload and their relevance in understanding skeletal muscle insulin resistance and pathological changes in mitochondrial oxidative capacity	7
Coronaviruses, cholesterol and statins: Involvement and application for Covid-19	7
Neuroprotective effect of 6-hydroxy-2,2,4-trimethyl-1,2-dihydroquinoline mediated via regulation of antioxidant system and inhibition of inflammation and apoptosis in a rat model of cerebral ischemia/	7
The glycoprotein gp63– a potential pan drug target for developing new antileishmanial agents	7
Glucose deprivation using 2-deoxyglucose and acarbose induce metabolic oxidative stress and apoptosis in female mice bearing breast cancer	6
Functional and structural characterization of an endo-β-1,3-glucanase from Euglena gracilis	6
Basic protein- and peptide-induced stabilization of long-loop DNA G-guadruplexes	6
DNA methyltransferase isoforms regulate endothelial cell exosome proteome composition	6
Comparison of the calcium signaling alterations in GABA-ergic medium spiny neurons produced from iPSCs of different origins	6
Anti-smoking drugs cytisine and varenicline reduce cardiac reperfusion injury in rat model of myocardial ischemia	6
Structure and function of Campylobacter jejuni polynucleotide phosphorylase (PNPase): Insights into the role of this RNase in pathogenicity	6
CogiTx1: A novel subtilisin A inhibitor isolated from the sea anemone Condylactis gigantea belonging to the defensin 4 protein family	6
Inhibitory effects of sesquiterpene lactones on the aggregation and cytotoxicity of prion neuropeptide	6
Crystal structure of Methionyl-tRNA Synthetase from Rickettsia typhi in complex with its cognate amino acid	6
Human transcriptional gene regulatory network compiled from 14 data resources	6
Generation of the novel anti-FXYD5 monoclonal antibody and its application to the diagnosis of pancreatic and lung cancer	6
Cholesterol accumulation induced by acetylated LDL exposure modifies the enzymatic activities of the TCA cycle without impairing the respiratory chain functionality in macrophages	6
Transcriptome analysis of HEK 293T cells revealed different significance of the depletion of DNA-dependent protein kinase subunits, Ku70, Ku80, and DNA-PKcs	6
α-Conotoxin RgIA and oligoarginine R8 in the mice model alleviate long-term oxaliplatin induced neuropathy	6
TRIM28 regulates transcriptional activity of methyl-DNA binding protein Kaiso by SUMOylation	6
Unveiling the structural mechanism of a G-quadruplex pH–Driven switch	6
Galactokinase-like protein from Leishmania donovani: Biochemical and structural characterization of a recombinant protein	6
Dioclea violacea lectin inhibits tumorigenesis and tumor angiogenesis in vivo	6
Epithelial mesenchymal transition induced nuclear localization of the extracellular matrix protein Fibronectin	6
Glycine disrupts myelin, glutamatergic neurotransmission, and redox homeostasis in a neonatal model for non ketotic hyperglycinemia	6
Transcriptional regulation of the Japanese flounder Cu,Zn-SOD (Jfsod1) gene in RAW264.7 cells during oxidative stress caused by causative bacteria of edwardsiellosis	6
Effects of natural polymorphisms in SARS-CoV-2 RNA-dependent RNA polymerase on its activity and sensitivity to inhibitors in vitro	6
Multiple stage linear ion-trap mass spectrometry toward characterization of native bacterial lipids-a critical review	6
Structural lessons on bacterial secretins	6
Characterization of novel truncated apolipoprotein A-I in human high-density lipoprotein generated by sequential treatment with myeloperoxidase and chymase	6
Purification and characterization of a hemocyanin with lectin-like activity isolated from the hemolymph of speckled shrimp, Metapenaeus monoceros	6
Stability and context of intercalated motifs (i-motifs) for biological applications	6
Schistosome TRPML channels play a role in neuromuscular activity and tegumental integrity	6
INTERPIN: A repository for intrinsic transcription termination hairpins in bacteria	6
Circadian clock gene disruption in white blood cells of patients with celiac disease	6
Counteracting diabetes-induced adipose tissue derived-stromal cell senescence	6
Sequencing of the Lumbricus terrestris genome reveals degeneracy in its erythrocruorin genes	6
Quadruplexes and aging: G4-binding proteins regulate the presence of miRNA in small extracellular vesicles (sEVs)	6
A new isoxazolyl-urea derivative induces apoptosis, paraptosis, and ferroptosis by modulating MAPKs in pancreatic cancer cells	6
The stability and function of human cochaperone Hsp40/DNAJA1 are affected by zinc removal and partially restored by copper	6
Effects of biophysical membrane properties on recognition of phosphatidylserine, or phosphatidylinositol 4-phosphate by lipid biosensors LactC2, or P4M	6
Analysis of the interaction of a non-canonical twin half-site of Cyclic AMP-Response Element (CRE) with CRE-binding protein	6
Coordination between human DNA polymerase β and apurinic/apyrimidinic endonuclease 1 in the course of DNA repair	6
Zinc binding loop mutations of hSOD1 promote amyloid fibrils under physiological conditions: Implications for initiation of amyotrophic lateral sclerosis	6
Dimer stilbene, a resveratrol analogue exhibits synergy with antibiotics that target protein synthesis in eradicating Staphylococcus aureus infection	6