Journal of Clinical Periodontology

Article	Citations
Cover Image	299
A Study Into Systemic and Oral Levels of Proinflammatory Biomarkers Associated With Endpoints After Active Non‐Surgical Periodontal Therapy	195
	194
Association between periodontal disease and microstructural brain alterations in the Hamburg City Health Study	162
Validation of a New Questionnaire for Assessing the Psychosocial Impact of Gingival Aesthetics (PIGAQ)	121
Recombinant human platelet‐derived growth factor improves root coverage of a collagen matrix for multiple adjacent gingival recessions: A triple‐blinded, randomized, placebo‐controlled trial	81
De‐epithelialized gingival graft versus subepithelial connective tissue graft in the treatment of multiple adjacent gingival recessions using the tunnel technique: 1‐year results of a randomized clini	78
In vivo evaluation of bone regeneration using ZIF8‐modified polypropylene membrane in rat calvarium defects	66
Association between asthma and periodontitis in the US adult population: A population‐based observational epidemiological study	56
	51
Issue Information	50
Effect of periodontal treatment on glycated haemoglobin and metabolic syndrome parameters: A randomized clinical trial	49
	49
Interleukin‐17 alleviates erastin‐induced alveolar bone loss by suppressing ferroptosis via interaction between NRF2 and p‐STAT3	49
The tree shrew as a new animal model for the study of periodontitis	49
Cover Image	47
Patient‐reported outcomes following dental implant rehabilitation according to reason for missing teeth: A survey from a Norwegian population 8 years following treatment	47
Issue Information	46
	42
	42
Can periodontal measures assist in the identification of adults with undiagnosed hyperglycaemia? A systematic review	42
Toll‐like receptor‐1, ‐2, and ‐6 genotypes in relation to salivary human beta‐defensin‐1, ‐2, ‐3 and human neutrophilic peptide‐1	41
Association of obesity and weight gain with alveolar bone loss: Results of the Northern Finland Birth Cohort 1966 study	40
Recombinant bone matrix maintains the graft space, induces vascularized bone regeneration and preserves canine tooth extraction socket structure	40
Regeneration of keratinized tissue around teeth and implants following coronal repositioning of alveolar mucosa with and without a connective tissue graft: An experimental study in dogs	40

Immediate implant placement with immediate or delayed provisionalization in the maxillary aesthetic zone: A 10‐year randomized trial	39
Tunnel technique with connective tissue graft versus coronally advanced flap with enamel matrix derivate for root coverage: 5‐year results of an RCT using 3D digital measurement technology for volumet	38
High‐intensity interval training mitigates the progression of periodontitis and improves behavioural aspects in rats	38
Issue Information	37
Cover Image	37
Issue Information	36
Outcomes of periodontal therapy in rheumatoid arthritis: The OPERA feasibility randomized trial	36
Improvement of periodontal parameters following intensive diabetes care and supragingival dental prophylaxis in patients with type 2 diabetes: A prospective cohort study	36
Correction to “Activation of PGC‐1 Alpha‐Dependent Mitochondrial Biogenesis Supports Therapeutic Effects of Silibinin Against Type I Diabetic Periodontitis”	35
Issue Information	34
Issue Information	34
Three‐dimensional imaging analysis of CAD/CAM custom‐milled versus prefabricated allogeneic block remodelling at 6 months and long‐term follow‐up of dental implants: A retrospect	33
Invasive dental treatment and acute vascular events: A systematic review and meta‐analysis	32
Flapless early implant placement into the uncalcified provisional matrix—Does it lead to osseointegration of the implant? A preclinical study	31
	31
	30
Cover Image	29
Periodontitis and the incidence of chronic obstructive pulmonary disease: A longitudinal study of an adult Japanese cohort	28
	28
The association between trypsin‐like protease activity in the oral cavity and kidney function in Japanese workers	28
Issue Information	28
Cover Image	28
	27
A randomized clinical trial to investigate the effect of dietary protein sources on periodontal health	27
Issue Information	27
Surface decontamination of explanted peri‐implantitis‐affected implants	27
Issue Information	27
Issue Information	27
Assessment of periodontitis grade in epidemiological studies using interdental attachment loss instead of radiographic bone loss	26
Surgical treatment of experimental peri‐implantitis using mechanical and chemical decontamination procedures: A pre‐clinical in vivo study	26
Deterioration of periodontal status affects declines in masticatory performance: The Suita study	26
CCR2 is a potential therapeutic target in peri‐implantitis	25
Invasive dental procedures as risk factors for postoperative spinal infection and the effect of antibiotic prophylaxis	25
The microbiome of dental and peri‐implant subgingival plaque during peri‐implant mucositis therapy: A randomized clinical trial	25
NLRP3‐mediated periodontal ligament cell pyroptosis promotes root resorption	24
Hypoxic Responses in Periodontal Tissues: Influence of Smoking and Periodontitis	24
Association between polycyclic aromatic hydrocarbons and periodontitis: Results from a large population‐based study	24
Is transmucosal healing of an implant as effective as submerged healing when simultaneous guided bone regeneration is performed? A preclinical study	23
Challenges and success in periodontal plastic surgery	23
Poster Discussion	23
The Potential Effect of Periodontal Disease on the Development of Metabolic Syndrome: A 10‐Year Observational Study in a Thai Adult Cohort	22
Development of gestational diabetes mellitus in women with periodontitis in early pregnancy: A population‐based clinical study	22
Bone Regeneration After Sinus Floor Elevation in an Intact Sinus or a Sinus With Prior Large Membrane Perforation: A Preclinical Study Using a Rabbit Sinus Model	22
Alpha‐Ketoglutarate Alleviates Systemic Lupus Erythematosus–Associated Periodontitis in a Novel Murine Model	22
Periodontal disease prevalence and oral hygiene status of adults with cystic fibrosis: A case–control study	21
Mediterranean diet component oleic acid increases protective lipid mediators and improves trabecular bone in a Porphyromonas gingivalis inoculation model	21
Adverse events of metronidazole and amoxicillin: Retrospective analysis of a large data set of five randomized clinical trials	21
Isobaric tags for relative and absolute quantification (iTRAQ)‐based quantitative analysis of the salivary proteome during healthy pregnancy and pregnancy gingivitis	21
Salivary annexin A1: A candidate biomarker for periodontitis	21
Impact of Various Detectable Interdental Clinical Attachment Loss Thresholds on the Estimated Prevalence, Stage and Extent of Periodontitis Based on the EFP/AAP Definition	21

Yogurt product intake and reduction of tooth loss risk in a Japanese community	20
Long‐term stability of infrabony defects treated with enamel matrix derivative alone: A retrospective two‐centre cohort study	20
Increased safety in periodontal surgery: Doppler ultrasound for detection of relevant palatal blood vessels—A proof‐of‐concept and cross‐sectional study	20
Single‐cell transcriptomic analysis of oral masticatory and lining mucosa‐derived mesenchymal stromal cells	19
Effect of different platelet‐rich fibrin matrices for ridge preservation in multiple tooth extractions: A split‐mouth randomized controlled clinical trial	19
Photo/mechanical and physical implant surface decontamination approaches in conjunction with surgical peri‐implantitis treatment: A systematic review	19
Periodontal pockets: Predictors for site‐related worsening after non‐surgical therapy—A long‐term retrospective cohort study	19
Efficacy and risks of removable partial prosthesis in periodontitis patients: A systematic review	19
Dynamic analyses of a soft tissue–implant interface: Biological responses to immediate versus delayed dental implants	19
Efficacy of rehabilitation of stage IV periodontitis patients with full‐arch fixed prostheses: Tooth‐supported versus Implant‐supported—A systematic review	19
Research on racial/ethnic inequities in oral health over the past 80 years: The role of racism	19
Exploring periodontitis misclassification mechanisms under partial‐mouth protocols	19
Oral microbiome diversity and diet quality in relation to mortality	19
Efficacy of access flap and pocket elimination procedures in the management of peri‐implantitis: A systematic review and meta‐analysis	19
Factors influencing tooth loss in European populations	19
Hard and soft tissue healing around teeth prepared with the biologically oriented preparation technique and restored with provisional crowns: An in vivo experimental investigation	19
Erratum	18
Efficacy of chemical approaches for implant surface decontamination in conjunction with sub‐marginal instrumentation, in the non‐surgical treatment of peri‐implantitis: A systematic review	18
RSPO4 is a potential risk gene of stages III–IV, grade C periodontitis through effects on innate immune response and oral barrier integrity	18
Multimorbid disease trajectories for people with periodontitis	18
No benefit of an adjunctive phototherapy protocol in treatment of periodontitis: A split‐mouth randomized controlled trial	18
Contribution of individual and cumulative social determinants of health underlying gender disparities in periodontitis in a representative US population: A cross‐sectional NHANES study	18
The loss of molars in supportive periodontal care: A 10‐year follow‐up for tooth‐ and patient‐related factors	18
A genome‐wide association study meta‐analysis in a European sample of stage III/IV grade C periodontitis patients ≤35 years of age identifies new risk loci	17
All‐cause and cause‐specific mortality in US adults with periodontal diseases: A prospective cohort study	17
Influence of low insertion torque values on survival rate of immediately loaded dental implants: A systematic review and meta‐analysis	17
Shift work sleep disorder is closely associated with an increased risk for periodontal disease	17
CORRIGENDUM	17
Associations of dietary antioxidant intake with periodontal health among US adults: An exploratory mediation analysis via mitochondrial function	17
Understanding the consequences of educational inequalities on periodontitis: A Mendelian randomization study	17
Development of a machine learning multiclass screening tool for periodontal health status based on non‐clinical parameters and salivary biomarkers	16
Treatment of stage IV periodontitis: The EFP S3 level clinical practice guideline	16
Dental Calculus Formation Rate: The Role of Salivary Proteome and Metaproteome	16
Assessment of gingival thickness in multi‐ethnic subjects with different gingival pigmentation levels	16
Association between circulating 25‐hydroxyvitamin D metabolites and periodontitis: Results from the NHANES 2009–2012 and Mendelian randomization study	16
Molecular biomarker research in periodontology: A roadmap for translation of science to clinical assay validation	16
Cytokine profiles and the dynamic of gingivitis development in humans	16
Recurrence and progression of periodontitis and methods of management in long‐term care: A systematic review and meta‐analysis	16
LRP5 Down‐Regulation Exacerbates Inflammation and Alveolar Bone Loss in Periodontitis by Inhibiting PI3K/c‐FOS Signalling	16
Accuracy of periodontitis diagnosis obtained using multiple molecular biomarkers in oral fluids: A systematic review and meta‐analysis	16
Development and international validation of logistic regression and machine‐learning models for the prediction of 10‐year molar loss	16
Association of periodontitis with cognitive decline and its progression: Contribution of blood‐based biomarkers of Alzheimer's disease to this relationship	16
Comparison of Ultrasonography, CBCT, Transgingival Probing, Colour‐Coded and Periodontal Probe Transparency With Histological Gingival Thickness: A Diagnostic Accuracy Study Revisiting Thic	16
A Survey Among General Practitioners and Periodontal Specialists in Norway Documenting a Positive Attitude Towards Guideline‐Based Referral Practise	16
Coronally advanced flap versus tunnel technique for the treatment of peri‐implant soft tissue dehiscences with the connective tissue graft: A randomized, controlled clinical trial	16
Sex‐specific genetic factors affect the risk of early‐onset periodontitis in Europeans	15
Associations of periodontal disease and tooth loss with all‐cause and cause‐specific mortality in the Sister Study	15
Effect of sub‐marginal instrumentation before surgical treatment of peri‐implantitis: A multi‐centre randomized clinical trial	15
Two short implants versus one short implant with a cantilever: 5‐Year results of a randomized clinical trial	15
Association between periodontal diseases and cardiovascular diseases, diabetes and respiratory diseases: Consensus report of the Joint Workshop by the European Federation of Periodontology (EFP	15
Prevalence of periodontitis in dentate people between 2011 and 2020: A systematic review and meta‐analysis of epidemiological studies	15
Issue Information	15
Global, regional, and national burden of severe periodontitis, 1990–2019: An analysis of the Global Burden of Disease Study 2019	15
Editorial: Core outcome sets and measures for clinical trials in implant dentistry	15
Efficacy of adjunctive measures in the non‐surgical treatment of peri‐implantitis: A systematic review	15
Issue Information	14
Maintenance visit regularity has a different impact on periodontitis‐related tooth loss depending on patient staging and grading	14
On the reliability of clinical attachment level measurements	14
Reduced bone dimension in patients affected by oligodontia: A retrospective study on maxillary and mandibular CBCT	14
	14
Clinical outcomes following atrophic alveolar ridge reconstruction using collagenated xenogeneic bone block or autogenous bone block: One‐year follow‐up of a randomized controlled clinical	14
Axin2‐expressing cells in the periodontal ligament are regulated by bone morphogenetic protein signalling and play a pivotal role in periodontium development	14
	13
Subgingival microbiome in periodontal health, gingivitis and different stages of periodontitis	13
Issue Information	13
Probing the salivary proteome for prognostic biomarkers in response to non‐surgical periodontal therapy	13
	13
Acute‐phase response following one‐stage full‐mouth versus quadrant non‐surgical periodontal treatment in subjects with comorbid type 2 diabetes: A randomized clinical trial	13
Authors' Response: “Akkermansia muciniphila reduces Porphyromonas gingivalis induced inflammation and periodontal bone destruction”	13
Have extraction patterns in German adults with severe periodontitis changed between 2000 and 2010? Results from two cohort studies	13
Diabetes mellitus exacerbates inflammation in a murine model of ligature‐induced peri‐implantitis: A histological and microtomographic study	13
Issue Information	13
Serum lipoprotein subfractions are associated with the periodontal status: Results from the population‐based cohort SHIP‐TREND	13
	13
Association between periodontal diseases and chronic obstructive pulmonary disease: Evidence from sequential cross‐sectional and prospective cohort studies based on UK Biobank	13
Issue Information	13
Issue Information	12
Issue Information	12
A novel computer‐aided method for direct measurements and visualization of gingival margin changes	12
Emerging Applications of Digital Technologies for Periodontal Screening, Diagnosis and Prognosis in the Dental Setting	12

Issue Information	12
	12
Antibiotic prophylaxis dysregulates dental implant placement surgery‐induced osteoimmune wound healing and attenuates the alveolar bone–implant interface in mice	12
Issue Information	12
Cover Image	12
Association of short sleep with risk of periodontal disease: A meta‐analysis and Mendelian randomization study	12
	12
Efficacy of adjunctive measures in peri‐implant mucositis. A systematic review and meta‐analysis	12
Endoscopic Re‐Instrumentation of Intrabony Defect–Associated Deep Residual Periodontal Pockets Is Non‐Inferior to Papilla Preservation Flap Surgery: A Randomized Trial	11
Free sugars and gingival inflammation: A systematic review and meta‐analysis	11
Clinical, microbiological, and immunological effects of 3‐ or 7‐day systemic antibiotics adjunctive to subgingival instrumentation in patients with aggressive (Stage III/IV Grade	11
Efficacy of tooth splinting and occlusal adjustment in patients with periodontitis exhibiting masticatory dysfunction: A systematic review	11
A Modified Ligature‐Induced Peri‐Implantitis Murine Model and RNA Sequencing Analysis Compared With Human Subjects	11
Contrast‐Enhanced Micro‐CT Imaging of Murine Mandibles: A Multi‐Method Approach for Simultaneous Hard and Soft Tissue Analysis	11
Understanding the role of endotoxin tolerance in chronic inflammatory conditions and periodontal disease	11
Single‐cell analysis reveals a unique microenvironment in peri‐implantitis	11
Human gingival mesenchymal stem cell‐derived exosomes cross‐regulate the Wnt/β‐catenin and NF‐κB signalling pathways in the periodontal inflammation microenvironment	11
High‐yield nanovesicles extruded from dental follicle stem cells promote the regeneration of periodontal tissues as an alternative of exosomes	11
Association between biological ageing and periodontitis: Evidence from a cross‐sectional survey and multi‐omics Mendelian randomization analysis	11
Randomized controlled multi‐centre study comparing shorter dental implants (6 mm) to longer dental implants (11–15 mm) in combination with sinus floor elevation procedures: 10‐year data	11
	11
A fast and reliable method for semi‐automated planimetric quantification of dental plaque in clinical trials	11
Have you had bleeding from your gums? Self‐report to identify giNGival inflammation (The SING diagnostic accuracy and diagnostic model development study)	10
Clinical outcomes and associated factors in the treatment of peri‐implant mucositis, combining mechanical debridement and prosthesis modification: A 30‐month follow‐up prospective case series	10
The efficacy of combining adjuvants with non‐surgical periodontal therapy in individuals with type 2 diabetes: A Bayesian network meta‐analysis	10
Efficacy of tooth‐supported compared to implant‐supported full‐arch removable prostheses in patients with terminal dentition. A systematic review	10
Prevention and management of peri‐implant mucositis and peri‐implantitis: A systematic review of outcome measures used in clinical studies in the last 10 years	10
Cross‐sectional association between severe periodontitis and diabetes mellitus: A nation‐wide cohort study	10
Response to Letter to the Editor “Diabetes and periodontitis”	10
Effect of subgingival periodontal therapy on glycaemic control in type 2 diabetes patients: Meta‐analysis and meta‐regression of 6‐month follow‐up randomized clinical trials	10
Effectiveness of implant‐supported fixed partial denture in patients with history of periodontitis: A systematic review and meta‐analysis	10
Periodontitis stage and grade modifies the benefit of regular supportive periodontal care in terms of need for retreatment and mean cumulative cost	10
Decision‐making on systemic antibiotics in the management of periodontitis: A retrospective comparison of two concepts	10
Comparative study of dedifferentiated fat cell and adipose‐derived stromal cell sheets for periodontal tissue regeneration: In vivo and in vitro evidence	10
Replication of gene polymorphisms associated with periodontitis‐related traits in an elderly cohort: the Washington Heights/Inwood Community Aging Project Ancillary Study of Oral Health	10
Correction to “Selective BET inhibitor RVX‐208 ameliorates periodontal inflammation and bone loss”	9
The potential causal path between periodontitis stage diagnosis and vegetable consumption is mediated by loss of posterior functional tooth units and masticatory function	9
Periodontitis Is Associated With Arterial Stiffness as Measured by Serial Cardio‐Ankle Vascular Index (CAVI): A 10‐Year Cohort Study	9
A vitronectin‐derived peptide prevents and restores alveolar bone loss by modulating bone re‐modelling and expression of RANKL and IL‐17A	9
Hyperglycaemia aggravates periodontal inflamm‐aging by promoting SETDB1‐mediated LINE‐1 de‐repression in macrophages	9
The effect of timing of orthodontic therapy on the outcomes of regenerative periodontal surgery in patients with stage IV periodontitis: A multicenter randomized trial	9
Treatment of gingivitis is associated with reduction of systemic inflammation and improvement of oral health‐related quality of life: A randomized clinical trial	9
Selective BET inhibitor RVX‐208 ameliorates periodontal inflammation and bone loss	9
Effect of the Mediterranean diet on gingivitis: A randomized controlled trial	9
Differential associations of rheumatoid arthritis and periodontitis or tooth loss: A cross‐sectional study	9
Use of the deep learning approach to measure alveolar bone level	9
Dietary inflammatory potential is associated with poor periodontal health: A population‐based study	9
Surgical treatment of peri‐implantitis with or without a deproteinized bovine bone mineral and a native bilayer collagen membrane: A randomized clinical trial	9
Prevalence of self‐reported severe periodontitis: Data from the population‐based CONSTANCES cohort	9
Persisting Chronic Periodontal Disease as a Risk Factor for Cardiovascular Disease: A Nationwide Population‐Based Cohort Study	9
Rehabilitation of full‐arch edentulism with fixed or removable dentures retained by root‐form dental implants: A systematic review of outcomes and outcome measures used in clinical research in the las	9
Influence of aging on periodontal regenerative therapy using enamel matrix derivative: A 3‐year prospective cohort study	9
Genotype‐driven NPC1L1 and PCSK9 inhibition and reduced risk of periodontitis	9
Molar Incisor Hypomineralization and Periodontitis in Adolescents: A Population‐Based Study	9
Prevalence of periodontitis based on the 2017 classification in a Norwegian population: The HUNT study	9
CCL2 is a key regulator and therapeutic target for periodontitis	9
Periodontitis is associated with multimorbidity in a large dental school population	8
Cross‐linked hyaluronic acid gel with or without a collagen matrix in the treatment of class III furcation defects: A histologic and histomorphometric study in dogs	8
Effect of periodontal therapy on glycaemic control in type 2 diabetes	8
Attempts to Modify Periodontal Screening Models Based on a Self‐Reported Oral Health Questionnaire in the Medical Care Setting	8
Pasteurized Akkermansia muciniphila reduces periodontal and systemic inflammation induced by Porphyromonas gingivalis in lean and obese mice	8
The combination of experimental periodontitis and oral microbiota from periodontitis patients aggravates liver fibrosis in mice	8
Diagnostic accuracy of salivary active matrix metalloproteinase (aMMP)‐8 point‐of‐care test for detecting periodontitis in adults: A systematic review and meta‐analysis	8
Contemporary educational methods in periodontology	8
Diagnostic accuracy of a point‐of‐care aMMP‐8 test in the discrimination of periodontal health and disease	8
Low bone mineral density is associated with severe periodontitis at the end of the second decade of life: A population‐based study	8
The association of sedentary behaviour and physical activity with periodontal disease in NHANES 2011–2012	8
Association Between Serum Levels of Perfluoroalkyl and Polyfluoroalkyl Substances and Dental Floss Use: The Double‐Edged Sword of Dental Floss Use—A Cross‐Sectional Study	8
Testing the association between tobacco smoking, alcohol consumption, and risk of periodontitis: A Mendelian randomization study	8
Effect of periodontal phenotype characteristics on post‐extraction dimensional changes of the alveolar ridge: A prospective case series	8
Platelet‐rich fibrin combined with a particulate bone substitute versus guided bone regeneration in the damaged extraction socket: An in vivo study	8
Effect of combined periodontal and orthodontic treatment of tilted molars and of teeth with intra‐bony and furcation defects in stage‐IV periodontitis patients: A systematic review	8
Investigating the causal effect of cognition on the self‐reported loss of functional dentition using marginal structural models: The Panel on Health and Ageing of Singaporean Elderly study	8
Ridge Augmentation Using a Self‐Retaining Block Bone Material in Damaged Extraction Sockets: A Multi‐Centre Randomized Controlled Clinical Trial	8
EXPRESSION OF CONCERN: Role of Cytokines in Development of Pre‐Eclampsia Associated with Periodontal Disease—Cohort Study	7
Issue Information	7
Consensus report of the second European Consensus Workshop on Education in Periodontology	7
	7
	7
Issue Information	7
Comparison of the efficacy of periodontal prognostic systems in predicting tooth loss	7
Impact of Vertical Inter‐Implant Distance in Two Adjacent Single‐Unit Posterior Implants: A Retrospective Cohort Study With 1–8 Years of Follow‐Up	7
Longitudinal association between periodontal condition and glycaemic status in middle‐aged adults: A cross‐lagged panel analysis	7
Issue Information	7
Excessive inflammatory response to infection in experimental peri‐implantitis: Resolution by Resolvin D2	7
	7
Comparing periodontitis biomarkers in saliva, oral rinse and gingival crevicular fluid: A pilot study	7
A quantitative bias analysis to assess the impact of unmeasured confounding on associations between diabetes and periodontitis	7
Subgingival host–microbiome metatranscriptomic changes following scaling and root planing in grade II/III periodontitis	7
Serum levels of vitamin D and periodontal inflammation in community‐dwelling older Japanese adults: The Otassha Study	7
Gingipains may be one of the key virulence factors of Porphyromonas gingivalis to impair cognition and enhance blood–brain barrier permeability: An animal study	7
	7
Parents with periodontitis drive the early acquisition of dysbiotic microbiomes in their offspring	7
Low energy intake and nutritional maladaptation in terminal stage IV periodontitis	7
Publisher's Note	7