Cancer Letters

Papers
(The H4-Index of Cancer Letters is 60. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Extrinsic factors associated with the response to immunotherapy in glioblastoma312
Editorial Board269
Ethnic Diversity and Metabolic Variations in Ovarian Cancer Cells: Implications for Personalized Medicine Strategies259
Versatility of Exosomes for Cancer Therapy196
Editorial Board167
ASPH dysregulates cell death and induces chemoresistance in hepatocellular carcinoma155
An emerging aspect of cancer neuroscience: A literature review on chemotherapy-induced peripheral neuropathy151
Selpercatinib mitigates cancer cachexia independent of anti-tumor activity in the HT1080 tumor model146
Nervous system in colorectal cancer141
Bypassing the Tollway; a novel path to TLR4 independent stemness regulation129
Intratumoral injection of mRNA encoding survivin in combination with STAT3 inhibitor stattic enhances antitumor effects128
Coiled-coil domain-containing 154 promotes colorectal cancer proliferation and metastasis via interacting with minichromosome maintenance complex component 2126
KAT7 enhances the proliferation and metastasis of head and neck squamous carcinoma by promoting the acetylation level of LDHA124
Regulation of gut microbiota on immune cell ferroptosis: A novel insight for immunotherapy against tumor122
Induction of EnR stress by Melatonin enhances the cytotoxic effect of Lapatinib in HER2-positive breast cancer115
Editorial Board114
Osteopontin promotes tumor microenvironment remodeling and therapy resistance111
Evaluation and preservation of fertility in patients with hematologic malignancies102
Targeted inhibition of acidic nucleoplasmic DNA-binding protein 1 enhances radiosensitivity of non-small cell lung cancer100
Targeting p53 for immune modulation: Exploring its functions in tumor immunity and inflammation97
Accelerating the clinical translation of CD70-targeted chimeric antigen receptor-based cell therapies in oncology: A comprehensive clinical investigation panorama analysis based on the Trialtrove data95
Interleukin-17 activates and synergizes with the notch signaling pathway in the progression of pancreatic ductal adenocarcinoma95
Targeting LINC01607 sensitizes hepatocellular carcinoma to Lenvatinib via suppressing mitophagy94
PI3K inhibitor impairs tumor progression and enhances sensitivity to anlotinib in anlotinib-resistant osteosarcoma92
Understanding the significance of biological clock and its impact on cancer incidence92
Clinical development of immuno-oncology therapeutics90
Jolkinolide B targets thioredoxin and glutathione systems to induce ROS-mediated paraptosis and apoptosis in bladder cancer cells90
Exosomal circ_0030167 derived from BM-MSCs inhibits the invasion, migration, proliferation and stemness of pancreatic cancer cells by sponging miR-338-5p and targeting the Wif1/Wnt8/β-catenin axis87
ERBB3 targeting: A promising approach to overcoming cancer therapeutic resistance86
CXCL13 promotes intestinal tumorigenesis through the activation of epithelial AKT signaling86
FAP upregulates PD-L1 expression in cancer-associated fibroblasts to exacerbate T cells dysfunction and suppress anti-tumor immunity86
MDSCs in bone metastasis: Mechanisms and therapeutic potential85
Targeted inhibition of the expression of both MCM5 and MCM7 by miRNA-214 impedes DNA replication and tumorigenesis in hepatocellular carcinoma cells84
Valproate and lithium: Old drugs for new pharmacological approaches in brain tumors?82
IBI379, a novel B cell maturation antigen/CD3 bispecific T-cell engager, displays high antitumor efficacy in preclinical models of multiple myeloma79
Dual mTORC1/2 inhibitor AZD2014 diminishes myeloid-derived suppressor cells accumulation in ovarian cancer and delays tumor growth78
Metronomic chemotherapy regimens and targeted therapies in non-Hodgkin lymphoma: The best of two worlds78
Cancer-associated fibroblasts in non-small cell lung cancer: Recent advances and future perspectives77
Intracellular AGR2 transduces PGE2 stimuli to promote epithelial–mesenchymal transition and metastasis of colorectal cancer77
Tuning cellular metabolism for cancer virotherapy76
The E3 ligase TRIM22 functions as a tumor suppressor in breast cancer by targeting CCS for proteasomal degradation to inhibit STAT3 signaling74
A natural compound melatonin enhances the effects of Nimotuzumab via inhibiting EGFR in glioblastoma74
METTL3 regulates M6A methylation-modified EBV-pri-miR-BART3-3p to promote NK/T cell lymphoma growth74
Increasing membrane polyunsaturated fatty acids sensitizes non-small cell lung cancer to anti-PD-1/PD-L1 immunotherapy73
The role of Hippo/YAP1 in cancer-associated fibroblasts: Literature review and future perspectives73
TIM3 on natural killer cells regulates antibody-dependent cellular cytotoxicity in HER2-positive gastric cancer69
Neoantigen discovery and applications in glioblastoma: An immunotherapy perspective69
LCAT deficiency promotes hepatocellular carcinoma progression and lenvatinib resistance by promoting triglyceride catabolism and fatty acid oxidation68
Combination treatment with 17β-estradiol and anti-PD-L1 suppresses MC38 tumor growth by reducing PD-L1 expression and enhancing M1 macrophage population in MC38 colon tumor model67
CD147-specific chimeric antigen receptor T cells effectively inhibit T cell acute lymphoblastic leukemia66
PROTACs: Novel tools for improving immunotherapy in cancer66
Ubiquitin-specific peptidase 22 in cancer65
Integrated analysis of ascites and plasma extracellular vesicles identifies a miRNA-based diagnostic signature in ovarian cancer65
Tumor-targeted exosomes for delivery of anticancer drugs65
M6A-modified lncRNA FAM83H-AS1 promotes colorectal cancer progression through PTBP164
CD155 in tumor progression and targeted therapy64
Sphingosine-1 phosphate receptor 1 (S1PR1) expression maintains stemness of acute myeloid leukemia stem cells64
CSNK2A1 confers gemcitabine resistance to pancreatic ductal adenocarcinoma via inducing autophagy63
Hypoxia effects on glioblastoma progression through YAP/TAZ pathway regulation61
Fatty acids in cancer chemoresistance60
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