Cancer Letters

Papers
(The TQCC of Cancer Letters is 19. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-07-01 to 2025-07-01.)
ArticleCitations
Editorial Board324
Ethnic Diversity and Metabolic Variations in Ovarian Cancer Cells: Implications for Personalized Medicine Strategies281
Versatility of Exosomes for Cancer Therapy267
Editorial Board199
An emerging aspect of cancer neuroscience: A literature review on chemotherapy-induced peripheral neuropathy170
Selpercatinib mitigates cancer cachexia independent of anti-tumor activity in the HT1080 tumor model158
Nervous system in colorectal cancer155
Bypassing the Tollway; a novel path to TLR4 independent stemness regulation145
Intratumoral injection of mRNA encoding survivin in combination with STAT3 inhibitor stattic enhances antitumor effects133
Editorial Board132
Osteopontin promotes tumor microenvironment remodeling and therapy resistance131
PROTACs: Novel tools for improving immunotherapy in cancer129
Extrinsic factors associated with the response to immunotherapy in glioblastoma126
The stromal microenvironment endows pancreatic neuroendocrine tumors with spatially specific invasive and metastatic phenotypes117
Comparable survival outcomes in HLA-Matched and haploidentical hematopoietic stem cell transplantation for severe aplastic anemia patients aged 40–50: A CBMTR Registry-based propensity score matching 116
Understanding the significance of biological clock and its impact on cancer incidence116
M6A-modified lncRNA FAM83H-AS1 promotes colorectal cancer progression through PTBP1107
The interplay between autophagy and apoptosis: its implication in lung cancer and therapeutics105
Targeting LINC01607 sensitizes hepatocellular carcinoma to Lenvatinib via suppressing mitophagy103
Valproate and lithium: Old drugs for new pharmacological approaches in brain tumors?98
Evaluation and preservation of fertility in patients with hematologic malignancies96
Targeted inhibition of acidic nucleoplasmic DNA-binding protein 1 enhances radiosensitivity of non-small cell lung cancer95
Clinical development of immuno-oncology therapeutics94
Induction of EnR stress by Melatonin enhances the cytotoxic effect of Lapatinib in HER2-positive breast cancer93
CD147-specific chimeric antigen receptor T cells effectively inhibit T cell acute lymphoblastic leukemia92
Fatty acids in cancer chemoresistance90
Ubiquitin-specific peptidase 22 in cancer90
The landscape of malignant transition: Unraveling cancer cell-of-origin and heterogeneous tissue microenvironment89
Targeting p53 for immune modulation: Exploring its functions in tumor immunity and inflammation89
Chaperone directed heterobifunctional molecules circumvent KRASG12C inhibitor resistance88
CXCL13 promotes intestinal tumorigenesis through the activation of epithelial AKT signaling87
IBI379, a novel B cell maturation antigen/CD3 bispecific T-cell engager, displays high antitumor efficacy in preclinical models of multiple myeloma86
Dual mTORC1/2 inhibitor AZD2014 diminishes myeloid-derived suppressor cells accumulation in ovarian cancer and delays tumor growth82
TIM3 on natural killer cells regulates antibody-dependent cellular cytotoxicity in HER2-positive gastric cancer80
MDSCs in bone metastasis: Mechanisms and therapeutic potential80
Metronomic chemotherapy regimens and targeted therapies in non-Hodgkin lymphoma: The best of two worlds80
Sphingosine-1 phosphate receptor 1 (S1PR1) expression maintains stemness of acute myeloid leukemia stem cells79
Neoantigen discovery and applications in glioblastoma: An immunotherapy perspective78
A natural compound melatonin enhances the effects of Nimotuzumab via inhibiting EGFR in glioblastoma77
Increasing membrane polyunsaturated fatty acids sensitizes non-small cell lung cancer to anti-PD-1/PD-L1 immunotherapy76
Combination treatment with 17β-estradiol and anti-PD-L1 suppresses MC38 tumor growth by reducing PD-L1 expression and enhancing M1 macrophage population in MC38 colon tumor model75
CSNK2A1 confers gemcitabine resistance to pancreatic ductal adenocarcinoma via inducing autophagy74
Tumor-targeted exosomes for delivery of anticancer drugs72
ASPH dysregulates cell death and induces chemoresistance in hepatocellular carcinoma69
Coiled-coil domain-containing 154 promotes colorectal cancer proliferation and metastasis via interacting with minichromosome maintenance complex component 269
Intracellular AGR2 transduces PGE2 stimuli to promote epithelial–mesenchymal transition and metastasis of colorectal cancer69
LCAT deficiency promotes hepatocellular carcinoma progression and lenvatinib resistance by promoting triglyceride catabolism and fatty acid oxidation68
Targeted inhibition of the expression of both MCM5 and MCM7 by miRNA-214 impedes DNA replication and tumorigenesis in hepatocellular carcinoma cells68
Regulation of gut microbiota on immune cell ferroptosis: A novel insight for immunotherapy against tumor68
FAP upregulates PD-L1 expression in cancer-associated fibroblasts to exacerbate T cells dysfunction and suppress anti-tumor immunity67
ERBB3 targeting: A promising approach to overcoming cancer therapeutic resistance67
Integrated analysis of ascites and plasma extracellular vesicles identifies a miRNA-based diagnostic signature in ovarian cancer66
PI3K inhibitor impairs tumor progression and enhances sensitivity to anlotinib in anlotinib-resistant osteosarcoma65
METTL3 regulates M6A methylation-modified EBV-pri-miR-BART3-3p to promote NK/T cell lymphoma growth65
Jolkinolide B targets thioredoxin and glutathione systems to induce ROS-mediated paraptosis and apoptosis in bladder cancer cells64
Accelerating the clinical translation of CD70-targeted chimeric antigen receptor-based cell therapies in oncology: A comprehensive clinical investigation panorama analysis based on the Trialtrove data62
CD155 in tumor progression and targeted therapy62
KAT7 enhances the proliferation and metastasis of head and neck squamous carcinoma by promoting the acetylation level of LDHA62
Exosomal circ_0030167 derived from BM-MSCs inhibits the invasion, migration, proliferation and stemness of pancreatic cancer cells by sponging miR-338-5p and targeting the Wif1/Wnt8/β-catenin axis61
Cancer-associated fibroblasts in non-small cell lung cancer: Recent advances and future perspectives61
The role of Hippo/YAP1 in cancer-associated fibroblasts: Literature review and future perspectives60
Tuning cellular metabolism for cancer virotherapy60
The E3 ligase TRIM22 functions as a tumor suppressor in breast cancer by targeting CCS for proteasomal degradation to inhibit STAT3 signaling59
Hypoxia effects on glioblastoma progression through YAP/TAZ pathway regulation59
S100A6 drives lymphatic metastasis of liver cancer via activation of the RAGE/NF-kB/VEGF-D pathway58
A high-affinity antibody-drug conjugates Actuximab-MMAE for potent and selective targeting of CEACAM5-Positive tumors57
Identification and characterization of Bufalin as a novel EGFR degrader57
Calcium channel TRPV6 promotes breast cancer metastasis by NFATC2IP57
Overexpression of nucleotide metabolic enzyme DUT in hepatocellular carcinoma potentiates a therapeutic opportunity through targeting its dUTPase activity57
ESDN inhibits melanoma progression by blocking E-selectin expression in endothelial cells via STAT357
Glucose restriction induces ROS-AMPK-mediated CTR1 expression and increases cisplatin efficiency in NSCLC56
A feedback circuit comprising EHD1 and 14-3-3ζ sustains β-catenin/c-Myc-mediated aerobic glycolysis and proliferation in non-small cell lung cancer56
R-spondin-3 promotes proliferation and invasion of breast cancer cells independently of Wnt signaling56
Tumor-derived miR-378a-3p-containing extracellular vesicles promote osteolysis by activating the Dyrk1a/Nfatc1/Angptl2 axis for bone metastasis56
Letter to the editor on ‘A deep neural network predictor to predict the sensitivity of neoadjuvant chemoradiotherapy in locally advanced rectal cancer’56
Targeting the genetic landscape of oral potentially malignant disorders has the potential as a preventative strategy in oral cancer56
FOXF2 expression triggered by endocrine therapy orchestrates therapeutic resistance through reorganization of chromatin architecture in breast cancer55
Corrigendum to “UBE2T promotes radiation resistance in non-small cell lung cancer via inducing epithelial-mesenchymal transition and the ubiquitination-mediated FOXO1 degradation” [Canc. Lett. 494 (2054
Corrigendum to “Discovery of YH677 as a cancer stemness inhibitor that suppresses triple-negative breast cancer growth and metastasis by regulating the TGFβ signaling pathway” [Canc. Lett. (2023) 216153
Targeting Amino Acid Dependency for Cancer Treatment53
Deubiquitinating PABPC1 by USP10 upregulates CLK2 translation to promote tumor progression in pancreatic ductal adenocarcinoma52
Editorial Board52
Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastases52
Plasmacytoid dendritic cells recruited by HIF-1α/eADO/ADORA1 signaling induce immunosuppression in hepatocellular carcinoma51
An effective two-stage NMBzA-induced rat esophageal tumor model revealing that the FAT-Hippo-YAP1 axis drives the progression of ESCC51
Cytomegalovirus infection of glioblastoma cells leads to NF-κB dependent upregulation of the c-MET oncogenic tyrosine kinase50
Inhibition of T-antigen expression promoting glycogen synthase kinase 3 impairs merkel cell carcinoma cell growth49
XRCC2 repairs mitochondrial DNA damage and fuels malignant behavior in hepatocellular carcinoma49
Understanding the cellular origin and progression of esophageal cancer using esophageal organoids49
ANKZF1 knockdown inhibits glioblastoma progression by promoting intramitochondrial protein aggregation through mitoRQC49
The combination of gemcitabine plus an anti-FGFR inhibitor can have a synergistic antitumor effect on FGF-activating cholangiocarcinoma48
Nanoparticles in the diagnosis and treatment of cancer metastases: Current and future perspectives48
Store-operated Ca2+ entry as a key oncogenic Ca2+ signaling driving tumor invasion-metastasis cascade and its translational potential48
Claudin-1 interacts with EPHA2 to promote cancer stemness and chemoresistance in colorectal cancer48
MEK-mediated CHPF2 phosphorylation promotes colorectal cancer cell proliferation and metastasis by activating NF-κB signaling47
The Tn antigen promotes lung tumor growth by fostering immunosuppression and angiogenesis via interaction with Macrophage Galactose-type lectin 2 (MGL2)47
Emerging roles of lysosome homeostasis (repair, lysophagy and biogenesis) in cancer progression and therapy47
Advancing neoadjuvant therapy with inetetamab for HER2-Positive breast cancer47
LKB1 inhibits telomerase activity resulting in cellular senescence through histone lactylation in lung adenocarcinoma46
MicroRNA-21 deficiency suppresses prostate cancer progression through downregulation of the IRS1-SREBP-1 signaling pathway46
PPAR agonists attenuate lenalidomide's anti-myeloma activity in vitro and in vivo45
Isorhapontigenin (ISO) inhibits EMT through FOXO3A/METTL14/VIMENTIN pathway in bladder cancer cells45
Improved antitumor effects elicited by an oncolytic HSV-1 expressing a novel B7H3nb/CD3 BsAb45
The intratumoral microbiome: Characterization methods and functional impact45
Conquering chemoresistance in pancreatic cancer: Exploring novel drug therapies and delivery approaches amidst desmoplasia and hypoxia45
Long noncoding RNA lnc-LEMGC combines with DNA-PKcs to suppress gastric cancer metastasis44
The feedback loop of AURKA/DDX5/TMEM147-AS1/let-7 drives lipophagy to induce cisplatin resistance in epithelial ovarian cancer44
Local delivery of optimized nanobodies targeting the PD-1/PD-L1 axis with a self-amplifying RNA viral vector induces potent antitumor responses44
Single-cell RNA-sequencing of human spleens reveals an IDO-1+ tolerogenic dendritic cell subset in pancreatic cancer patients that is absent in normal individuals44
CircUBE3A(2,3,4,5) promotes adenylate-uridylate-rich binding factor 1 nuclear translocation to suppress prostate cancer metastasis43
Circular RNA circPFKP promotes cell proliferation by activating IMPDH2 in prostate cancer43
FUT2-dependent fucosylation of LAMP1 promotes the apoptosis of colorectal cancer cells by regulating the autophagy-lysosomal pathway43
Low-dose metronomic chemotherapy triggers oxidized mtDNA sensing inside tumor cells to potentiate CD8+T anti-tumor immunity43
Novel SARS-CoV-2 inhibition properties of the anti-cancer Kang Guan Recipe herbal formula43
Single-cell chemokine receptor profiles delineate the immune contexture of tertiary lymphoid structures in head and neck squamous cell carcinoma43
Interplay among extracellular vesicles, cancer stemness and immune regulation in driving hepatocellular carcinoma progression42
DAB2IP suppresses tumor malignancy by inhibiting GRP75-driven p53 ubiquitination in colon cancer42
Functional genomic approaches in acute myeloid leukemia: Insights into disease models and the therapeutic potential of reprogramming42
Targeting WEE1 kinase as a therapeutic strategy in ATIP3-deficient breast cancers42
Human mesenchymal stromal cells maintain their stem cell traits after high-LET particle irradiation – Potential implications for particle radiotherapy and manned space missions42
A novel molecular subtyping based on multi-omics analysis for prognosis predicting in colorectal melanoma: A 16-year prospective multicentric study42
WEE1 confers resistance to KRASG12C inhibitors in non-small cell lung cancer42
Active immunization with a structurally aggregated PD-L1 antigen breaks T and B immune tolerance in non-human primates and exhibits in vivo anti-tumoral effects in immunocompetent mouse tumor models42
Corrigendum to “Circular RNA ciRS-7 accelerates ESCC progression through acting as a miR-876-5p sponge to enhance MAGE-A family expression” [Cancer Lett. 426 (2018) 37–46]41
Sorbitol dehydrogenase induction of cancer cell necroptosis and macrophage polarization in the HCC microenvironment suppresses tumor progression41
Corrigendum to “P-REX1 amplification promotes progression of cutaneous melanomavia the PAK1/P38/MMP-2 pathway” [Cancer Lett. 407 (2017) 66–75]41
LINC00978 regulates metabolic rewiring to promote the malignancy of glioblastoma through AKR1B141
hnRNPLL regulates MYOF alternative splicing and correlates with early metastasis in pancreatic ductal adenocarcinoma40
Early detection and intervention of clonal hematopoiesis for preventing hematological malignancies40
Spermatid perinuclear RNA-binding protein promotes UBR5-mediated proteolysis of Dicer to accelerate triple-negative breast cancer progression40
Editorial Board40
Smoking-induced CCNA2 expression promotes lung adenocarcinoma tumorigenesis by boosting AT2/AT2-like cell differentiation40
Editorial Board40
Develop a Novel Therapy for Pancreatic Cancer40
Decoding the potential microbiome modulation strategies from bugs to drugs in pancreatic cancer: Insights from clinical trials40
Retraction notice to “MicroRNA-19a and -19b regulate cervical carcinoma cell proliferation and invasion by targeting CUL5” [Canc. Lett. 322 (2012) 148–158]40
TRF2 cooperates with CTCF for controlling the oncomiR-193b-3p in colorectal cancer39
Editorial Board39
Phase separation of EEF1E1 promotes tumor stemness via PTEN/AKT-mediated DNA repair in hepatocellular carcinoma39
RNA binding protein RALY activates the cholesterol synthesis pathway through an MTA1 splicing switch in hepatocellular carcinoma39
Phosphorylation of PBK/TOPK Tyr74 by JAK2 promotes Burkitt lymphoma tumor growth39
Editorial Board39
Nanomaterials in crossroad of autophagy control in human cancers: Amplification of cell death mechanisms39
SENP1-Sirt3 axis promotes cholesterol biosynthesis in tumor-associated macrophages to suppress anti-tumor immunity39
WD repeat protein 54-mediator of ErbB2-driven cell motility 1 axis promotes bladder cancer tumorigenesis and metastasis and impairs chemosensitivity39
Mitochondrial fragmentation in liver cancer: Emerging player and promising therapeutic opportunities38
Dysregulation of autophagy in gastric carcinoma: Pathways to tumor progression and resistance to therapy38
Application prospect of circular RNA-based neoantigen vaccine in tumor immunotherapy38
REDD1 is a determinant of the sensitivity of renal cell carcinoma cells to autophagy inhibition that can be therapeutically exploited by targeting PIM activity38
Treatment strategies and molecular mechanism of radiotherapy combined with immunotherapy in colorectal cancer38
Pan-cancer atlas of tumor-resident microbiome, immunity and prognosis38
Remodeling of tumor microenvironment by extracellular matrix protein 1a differentially regulates ovarian cancer metastasis38
Long noncoding RNA KB-1460A1.5 inhibits glioma tumorigenesis via miR-130a-3p/TSC1/mTOR/YY1 feedback loop38
Fas signaling in adipocytes promotes low-grade inflammation and lung metastasis of colorectal cancer through interaction with Bmx38
Suppressive immune microenvironment and CART therapy for glioblastoma: Future prospects and challenges38
The safety and efficacy outcomes of Minnelide given alone or in combination with paclitaxel in advanced gastric cancer: A phase I trial38
ZC3H13-mediated N6-methyladenosine modification of PHF10 is impaired by fisetin which inhibits the DNA damage response in pancreatic cancer37
Depression in breast cancer patients: Immunopathogenesis and immunotherapy37
Frontiers in pancreatic cancer on biomarkers, microenvironment, and immunotherapy37
GPRC5A promotes gallbladder cancer metastasis by upregulating TNS4 via the JAK2–STAT3 pathway37
The post-chemotherapy changes of tumor physical microenvironment: Targeting extracellular matrix to address chemoresistance36
Mucins as contrast agent targets for fluorescence-guided surgery of pancreatic cancer36
Tumor-nerve interactions in cancer regulation and progression36
Radiotherapy-induced tumor physical microenvironment remodeling to overcome immunotherapy resistance36
Exercise in cancer prevention and anticancer therapy: Efficacy, molecular mechanisms and clinical information36
Non-muscle myosin II isoforms orchestrate substrate stiffness sensing to promote cancer cell contractility and migration36
Editorial Board35
Corrigendum to “Helicobacter pylori upregulates Nanog and Oct4 via Wnt/β-catenin signaling pathway to promote cancer stem cell-like properties in human gastric cancer” [Canc. Lett. 374 (2016) 292–303]35
Copper in hepatocellular carcinoma: A double-edged sword with therapeutic potentials35
Editorial Board35
Gold nanoparticles and obese adipose tissue microenvironment in cancer treatment35
Identification of SMARCAL1 as a molecular target for small cell lung cancer treatment35
A journey to excellence: Disseminating groundbreaking discoveries in oncology research35
Super-giant cells: Toward understanding tumor origins on the organismal level35
Corrigendum to “Scattered DUSP28 is a novel biomarker responsible for aggravating malignancy via the autocrine and paracrine signaling in metastatic pancreatic cancer” [Cancer Lett. 456 (2019 Aug 1) 135
Editorial Board35
Biodistribution and therapeutic efficacy of a gold nanoparticle-based targeted drug delivery system against pancreatic cancer34
CPSF3 regulates alternative polyadenylation of CNIH2 to promote esophageal squamous cell carcinoma progression34
Histone lactylation dynamics: Unlocking the triad of metabolism, epigenetics, and immune regulation in metastatic cascade of pancreatic cancer34
Corrigendum to “NSUN4 mediated RNA 5-methylcytosine promotes the malignant progression of glioma through improving the CDC42 mRNA stabilization” [Cancer Lett. (2024) 597 217059]34
Dual targeting PPARα and NPC1L1 metabolic vulnerabilities blocks tumorigenesis34
Disparities in mortality risk after diagnosis of hematological malignancies in 185 countries: A global data analysis34
SIK1 promotes ferroptosis resistance in pancreatic cancer via HDAC5-STAT6-SLC7A11 axis34
The eIF3a translational control axis in the Wnt/β-catenin signaling pathway and colon tumorigenesis34
Unlocking c-MET: A comprehensive journey into targeted therapies for breast cancer34
A novel GRK3-HDAC2 regulatory pathway is a key direct link between neuroendocrine differentiation and angiogenesis in prostate cancer progression34
Single-nucleus sequencing unveils heterogeneity in renal cell carcinomas microenvironment: Insights into pathogenic origins and treatment-responsive cellular subgroups34
E2F1 promotes proliferation and metastasis of clear cell renal cell carcinoma via activation of SREBP1-dependent fatty acid biosynthesis34
Letter to the editor regarding “Dual blockade of EGFR and CDK4/6 delays head and neck squamous cell carcinoma progression by inducing metabolic rewiring."34
High-content drug screening in zebrafish xenografts reveals high efficacy of dual MCL-1/BCL-XL inhibition against Ewing sarcoma34
WITHDRAWN: Proteomic analysis of plasma-derived exosomes identifies biomarkers that distinguish brain and liver metastasis in lung cancer patients34
Circadian disruption in cancer and regulation of cancer stem cells by circadian clock genes: An updated review34
Targeted inhibition of CHKα and mTOR in models of pancreatic ductal adenocarcinoma: A novel regimen for metastasis33
PI3K PROTAC overcomes the lapatinib resistance in PIK3CA-mutant HER2 positive breast cancer33
Single-cell transcriptomics reveals intratumor heterogeneity and the potential roles of cancer stem cells and myCAFs in colorectal cancer liver metastasis and recurrence33
Identification of SPP1+ macrophages in promoting cancer stemness via vitronectin and CCL15 signals crosstalk in liver cancer33
SLC7A11/ xCT is a target of miR-5096 and its restoration partially rescues miR-5096-mediated ferroptosis and anti-tumor effects in human breast cancer cells33
LncRNA-miRNA axes in breast cancer: Novel points of interaction for strategic attack32
Emerging insights into origin and pathobiology of primary central nervous system lymphoma32
Aging of the progenitor cells that initiate prostate cancer32
Editorial Board32
IgSF protein EWI2 is a tumor suppressor32
Revisiting the advances and challenges in the clinical applications of extracellular vesicles in cancer32
The mitotic regulator RCC2 promotes glucose metabolism through BACH1-dependent transcriptional upregulation of hexokinase II in glioma32
Targeting tumor-intrinsic SLC16A3 to enhance anti-PD-1 efficacy via tumor immune microenvironment reprogramming32
Editorial Board32
Editorial Board32
CRISPR/Cas9 screen reveals that targeting TRIM34 enhances ferroptosis sensitivity and augments immunotherapy efficacy in hepatocellular carcinoma32
Lipid metabolism reprogramming of CD8+ T cell and therapeutic implications in cancer32
Deciphering the tumor-suppressive role of PSMB9 in melanoma through multi-omics and single-cell transcriptome analyses32
EDARADD promotes colon cancer progression by suppressing E3 ligase Trim21-mediated ubiquitination and degradation of Snail32
Editorial Board32
Editorial Board32
Inflammatory cytokine-regulated LNCPTCTS suppresses thyroid cancer progression via enhancing Snail nuclear export31
Mutant IDH1 promotes phagocytic function of microglia/macrophages in gliomas by downregulating ICAM131
TFAP2C-DDR1 axis regulates resistance to CDK4/6 inhibitor in breast cancer31
The nuclear condensates of ESE3/EHF induce cellular senescence without the associated inflammatory secretory phenotype in pancreatic ductal adenocarcinoma31
The intersections between neuroscience and medulloblastoma31
Tumor-derived extracellular vesicles induce invalid cytokine release and exhaustion of CD19 CAR-T Cells31
Evolution and contemporary role of metronomic chemotherapy in the treatment of neuroblastoma31
Significance of longitudinal Epstein–Barr virus DNA combined with multipoint tumor response for dynamic risk stratification and treatment adaptation in nasopharyngeal carcinoma31
Extracellular vesicle biomarkers redefine prostate cancer radiotherapy31
Confusion about the article: Natural product triptolide induces GSDME-mediated pyroptosis in head and neck cancer through suppressing mitochondrial hexokinase-ΙΙ31
The novel long noncoding RNA AU021063, induced by IL-6/Arid5a signaling, exacerbates breast cancer invasion and metastasis by stabilizing Trib3 and activating the Mek/Erk pathway31
Proteolysis of a histone acetyl reader, ATAD2, induces chemoresistance of cancer cells under severe hypoxia by inhibiting cell cycle progression in S phase31
circCCNY enhances lenvatinib sensitivity and suppresses immune evasion in hepatocellular carcinoma by serving as a scaffold for SMURF1 mediated HSP60 degradation31
Editorial Board31
PPDPF promotes esophageal squamous cell carcinoma progression by blocking PCCA binding to PCCB and inhibiting methionine catabolism31
A novel microenvironment regulated system CAR-T (MRS.CAR-T) for immunotherapeutic treatment of esophageal squamous carcinoma31
CHEK2 deficiency increase the response to PD-1 inhibitors by affecting the tumor immune microenvironment31
Cancer-associated fibroblasts: A key target to snatch victory from defeat in therapy resistance associated with the pancreatic cancer stroma30
Targeting the molecular chaperone CCT2 inhibits GBM progression by influencing KRAS stability30
Cancer-associated fibroblast-like fibroblasts in vocal fold leukoplakia suppress CD8+T cell functions by inducing IL-6 autocrine loop and interacting with Th17 cells30
Loss of ASAP1 in the MMTV-PyMT model of luminal breast cancer activates AKT, accelerates tumorigenesis, and promotes metastasis30
ITPR1-AS1 promotes small cell lung cancer metastasis by facilitating P21 splicing and stabilizing DDX3X to activate the cRaf-MEK-ERK cascade30
The new era of pancreatic cancer treatment: Application of nanotechnology breaking through bottlenecks30
Magnolin targeting of the JNK/Sp1/MMP15 signaling axis suppresses cervical cancer microenvironment and metastasis via microbiota modulation30
Metformin inhibits neutrophil extracellular traps-promoted pancreatic carcinogenesis in obese mice30
IDO1/TDO dual inhibitor RY103 targets Kyn-AhR pathway and exhibits preclinical efficacy on pancreatic cancer30
AXL signal mediates adaptive resistance to KRAS G12C inhibitors in KRAS G12C-mutant tumor cells30
HMGB1 in the interplay between autophagy and apoptosis in cancer30
Inhibition of the endosomal recycling pathway downregulates HER2 activation and overcomes resistance to tyrosine kinase inhibitors in HER2-positive breast cancer30
Harnessing genetic interactions for prediction of immune checkpoint inhibitors response signature in cancer cells30
Multi-functional extracellular vesicles: Potentials in cancer immunotherapy30
Statin in combination with cisplatin makes favorable tumor-immune microenvironment for immunotherapy of head and neck squamous cell carcinoma30
How to design next-generation of antibody-drug conjugates for cancer treatment: Lessons from unsuccessful clinical trials30
Cope with copper: From copper linked mechanisms to copper-based clinical cancer therapies30
HSP90 inhibitor AUY922 suppresses tumor growth and modulates immune response through YAP1-TEAD pathway inhibition in gastric cancer29
Corrigendum to “Regulation of the Nampt-mediated NAD salvage pathway and its therapeutic implications in pancreatic cancer [Cancer Lett. 379 (2016) 1–11]29
Editorial Board29
0.11311984062195