Cancer Letters

Article	Citations
Extrinsic factors associated with the response to immunotherapy in glioblastoma	312
Editorial Board	269
Ethnic Diversity and Metabolic Variations in Ovarian Cancer Cells: Implications for Personalized Medicine Strategies	259
Versatility of Exosomes for Cancer Therapy	196
Editorial Board	167
ASPH dysregulates cell death and induces chemoresistance in hepatocellular carcinoma	155
An emerging aspect of cancer neuroscience: A literature review on chemotherapy-induced peripheral neuropathy	151
Selpercatinib mitigates cancer cachexia independent of anti-tumor activity in the HT1080 tumor model	146
Nervous system in colorectal cancer	141
Bypassing the Tollway; a novel path to TLR4 independent stemness regulation	129
Intratumoral injection of mRNA encoding survivin in combination with STAT3 inhibitor stattic enhances antitumor effects	128
Coiled-coil domain-containing 154 promotes colorectal cancer proliferation and metastasis via interacting with minichromosome maintenance complex component 2	126
KAT7 enhances the proliferation and metastasis of head and neck squamous carcinoma by promoting the acetylation level of LDHA	124
Regulation of gut microbiota on immune cell ferroptosis: A novel insight for immunotherapy against tumor	122
Induction of EnR stress by Melatonin enhances the cytotoxic effect of Lapatinib in HER2-positive breast cancer	115
Editorial Board	114
Osteopontin promotes tumor microenvironment remodeling and therapy resistance	111
Evaluation and preservation of fertility in patients with hematologic malignancies	102
Targeted inhibition of acidic nucleoplasmic DNA-binding protein 1 enhances radiosensitivity of non-small cell lung cancer	100
Targeting p53 for immune modulation: Exploring its functions in tumor immunity and inflammation	97
Interleukin-17 activates and synergizes with the notch signaling pathway in the progression of pancreatic ductal adenocarcinoma	95
Accelerating the clinical translation of CD70-targeted chimeric antigen receptor-based cell therapies in oncology: A comprehensive clinical investigation panorama analysis based on the Trialtrove data	95
Targeting LINC01607 sensitizes hepatocellular carcinoma to Lenvatinib via suppressing mitophagy	94
Understanding the significance of biological clock and its impact on cancer incidence	92
PI3K inhibitor impairs tumor progression and enhances sensitivity to anlotinib in anlotinib-resistant osteosarcoma	92

Jolkinolide B targets thioredoxin and glutathione systems to induce ROS-mediated paraptosis and apoptosis in bladder cancer cells	90
Clinical development of immuno-oncology therapeutics	90
Exosomal circ_0030167 derived from BM-MSCs inhibits the invasion, migration, proliferation and stemness of pancreatic cancer cells by sponging miR-338-5p and targeting the Wif1/Wnt8/β-catenin axis	87
CXCL13 promotes intestinal tumorigenesis through the activation of epithelial AKT signaling	86
FAP upregulates PD-L1 expression in cancer-associated fibroblasts to exacerbate T cells dysfunction and suppress anti-tumor immunity	86
ERBB3 targeting: A promising approach to overcoming cancer therapeutic resistance	86
MDSCs in bone metastasis: Mechanisms and therapeutic potential	85
Targeted inhibition of the expression of both MCM5 and MCM7 by miRNA-214 impedes DNA replication and tumorigenesis in hepatocellular carcinoma cells	84
Valproate and lithium: Old drugs for new pharmacological approaches in brain tumors?	82
IBI379, a novel B cell maturation antigen/CD3 bispecific T-cell engager, displays high antitumor efficacy in preclinical models of multiple myeloma	79
Metronomic chemotherapy regimens and targeted therapies in non-Hodgkin lymphoma: The best of two worlds	78
Dual mTORC1/2 inhibitor AZD2014 diminishes myeloid-derived suppressor cells accumulation in ovarian cancer and delays tumor growth	78
Cancer-associated fibroblasts in non-small cell lung cancer: Recent advances and future perspectives	77
Intracellular AGR2 transduces PGE2 stimuli to promote epithelial–mesenchymal transition and metastasis of colorectal cancer	77
Tuning cellular metabolism for cancer virotherapy	76
METTL3 regulates M6A methylation-modified EBV-pri-miR-BART3-3p to promote NK/T cell lymphoma growth	74
The E3 ligase TRIM22 functions as a tumor suppressor in breast cancer by targeting CCS for proteasomal degradation to inhibit STAT3 signaling	74
A natural compound melatonin enhances the effects of Nimotuzumab via inhibiting EGFR in glioblastoma	74
Increasing membrane polyunsaturated fatty acids sensitizes non-small cell lung cancer to anti-PD-1/PD-L1 immunotherapy	73
The role of Hippo/YAP1 in cancer-associated fibroblasts: Literature review and future perspectives	73
Neoantigen discovery and applications in glioblastoma: An immunotherapy perspective	69
TIM3 on natural killer cells regulates antibody-dependent cellular cytotoxicity in HER2-positive gastric cancer	69
LCAT deficiency promotes hepatocellular carcinoma progression and lenvatinib resistance by promoting triglyceride catabolism and fatty acid oxidation	68
Combination treatment with 17β-estradiol and anti-PD-L1 suppresses MC38 tumor growth by reducing PD-L1 expression and enhancing M1 macrophage population in MC38 colon tumor model	67
PROTACs: Novel tools for improving immunotherapy in cancer	66
CD147-specific chimeric antigen receptor T cells effectively inhibit T cell acute lymphoblastic leukemia	66
Integrated analysis of ascites and plasma extracellular vesicles identifies a miRNA-based diagnostic signature in ovarian cancer	65
Tumor-targeted exosomes for delivery of anticancer drugs	65
Ubiquitin-specific peptidase 22 in cancer	65
CD155 in tumor progression and targeted therapy	64
Sphingosine-1 phosphate receptor 1 (S1PR1) expression maintains stemness of acute myeloid leukemia stem cells	64
M6A-modified lncRNA FAM83H-AS1 promotes colorectal cancer progression through PTBP1	64
CSNK2A1 confers gemcitabine resistance to pancreatic ductal adenocarcinoma via inducing autophagy	63
Hypoxia effects on glioblastoma progression through YAP/TAZ pathway regulation	61
Fatty acids in cancer chemoresistance	60
The stromal microenvironment endows pancreatic neuroendocrine tumors with spatially specific invasive and metastatic phenotypes	59
The interplay between autophagy and apoptosis: its implication in lung cancer and therapeutics	59
ESDN inhibits melanoma progression by blocking E-selectin expression in endothelial cells via STAT3	58
S100A6 drives lymphatic metastasis of liver cancer via activation of the RAGE/NF-kB/VEGF-D pathway	58
ANKZF1 knockdown inhibits glioblastoma progression by promoting intramitochondrial protein aggregation through mitoRQC	58
Cytomegalovirus infection of glioblastoma cells leads to NF-κB dependent upregulation of the c-MET oncogenic tyrosine kinase	56
Letter to the editor on ‘A deep neural network predictor to predict the sensitivity of neoadjuvant chemoradiotherapy in locally advanced rectal cancer’	55
Glucose restriction induces ROS-AMPK-mediated CTR1 expression and increases cisplatin efficiency in NSCLC	55
A feedback circuit comprising EHD1 and 14-3-3ζ sustains β-catenin/c-Myc-mediated aerobic glycolysis and proliferation in non-small cell lung cancer	55
Overexpression of nucleotide metabolic enzyme DUT in hepatocellular carcinoma potentiates a therapeutic opportunity through targeting its dUTPase activity	55
A high-affinity antibody-drug conjugates Actuximab-MMAE for potent and selective targeting of CEACAM5-Positive tumors	55
An effective two-stage NMBzA-induced rat esophageal tumor model revealing that the FAT-Hippo-YAP1 axis drives the progression of ESCC	55
Calcium channel TRPV6 promotes breast cancer metastasis by NFATC2IP	55
FOXF2 expression triggered by endocrine therapy orchestrates therapeutic resistance through reorganization of chromatin architecture in breast cancer	54
Deubiquitinating PABPC1 by USP10 upregulates CLK2 translation to promote tumor progression in pancreatic ductal adenocarcinoma	54

Targeting Amino Acid Dependency for Cancer Treatment	53
Corrigendum to “Discovery of YH677 as a cancer stemness inhibitor that suppresses triple-negative breast cancer growth and metastasis by regulating the TGFβ signaling pathway” [Canc. Lett. (2023) 2161	53
Improved antitumor effects elicited by an oncolytic HSV-1 expressing a novel B7H3nb/CD3 BsAb	53
Corrigendum to “UBE2T promotes radiation resistance in non-small cell lung cancer via inducing epithelial-mesenchymal transition and the ubiquitination-mediated FOXO1 degradation” [Canc. Lett. 494 (20	53
Editorial Board	53
R-spondin-3 promotes proliferation and invasion of breast cancer cells independently of Wnt signaling	52
Claudin-1 interacts with EPHA2 to promote cancer stemness and chemoresistance in colorectal cancer	51
Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastases	51
Understanding the cellular origin and progression of esophageal cancer using esophageal organoids	51
MicroRNA-21 deficiency suppresses prostate cancer progression through downregulation of the IRS1-SREBP-1 signaling pathway	51
XRCC2 repairs mitochondrial DNA damage and fuels malignant behavior in hepatocellular carcinoma	51
Plasmacytoid dendritic cells recruited by HIF-1α/eADO/ADORA1 signaling induce immunosuppression in hepatocellular carcinoma	50
Store-operated Ca2+ entry as a key oncogenic Ca2+ signaling driving tumor invasion-metastasis cascade and its translational potential	49
MEK-mediated CHPF2 phosphorylation promotes colorectal cancer cell proliferation and metastasis by activating NF-κB signaling	49
Conquering chemoresistance in pancreatic cancer: Exploring novel drug therapies and delivery approaches amidst desmoplasia and hypoxia	49
Nanoparticles in the diagnosis and treatment of cancer metastases: Current and future perspectives	49
The Tn antigen promotes lung tumor growth by fostering immunosuppression and angiogenesis via interaction with Macrophage Galactose-type lectin 2 (MGL2)	48
Isorhapontigenin (ISO) inhibits EMT through FOXO3A/METTL14/VIMENTIN pathway in bladder cancer cells	48
The combination of gemcitabine plus an anti-FGFR inhibitor can have a synergistic antitumor effect on FGF-activating cholangiocarcinoma	48
The intratumoral microbiome: Characterization methods and functional impact	47
Inhibition of T-antigen expression promoting glycogen synthase kinase 3 impairs merkel cell carcinoma cell growth	47
LKB1 inhibits telomerase activity resulting in cellular senescence through histone lactylation in lung adenocarcinoma	47
Emerging roles of lysosome homeostasis (repair, lysophagy and biogenesis) in cancer progression and therapy	46
Tumor-derived miR-378a-3p-containing extracellular vesicles promote osteolysis by activating the Dyrk1a/Nfatc1/Angptl2 axis for bone metastasis	46
The feedback loop of AURKA/DDX5/TMEM147-AS1/let-7 drives lipophagy to induce cisplatin resistance in epithelial ovarian cancer	46
Targeting the genetic landscape of oral potentially malignant disorders has the potential as a preventative strategy in oral cancer	46
FUT2-dependent fucosylation of LAMP1 promotes the apoptosis of colorectal cancer cells by regulating the autophagy-lysosomal pathway	45
Tumor-nerve interactions in cancer regulation and progression	45
Novel SARS-CoV-2 inhibition properties of the anti-cancer Kang Guan Recipe herbal formula	45
DAB2IP suppresses tumor malignancy by inhibiting GRP75-driven p53 ubiquitination in colon cancer	45
A novel molecular subtyping based on multi-omics analysis for prognosis predicting in colorectal melanoma: A 16-year prospective multicentric study	44
Targeting WEE1 kinase as a therapeutic strategy in ATIP3-deficient breast cancers	44
Interplay among extracellular vesicles, cancer stemness and immune regulation in driving hepatocellular carcinoma progression	44
Functional genomic approaches in acute myeloid leukemia: Insights into disease models and the therapeutic potential of reprogramming	43
Circular RNA circPFKP promotes cell proliferation by activating IMPDH2 in prostate cancer	43
Treatment strategies and molecular mechanism of radiotherapy combined with immunotherapy in colorectal cancer	43
WEE1 confers resistance to KRASG12C inhibitors in non-small cell lung cancer	43
Single-cell RNA-sequencing of human spleens reveals an IDO-1+ tolerogenic dendritic cell subset in pancreatic cancer patients that is absent in normal individuals	43
Human mesenchymal stromal cells maintain their stem cell traits after high-LET particle irradiation – Potential implications for particle radiotherapy and manned space missions	42
Corrigendum to “Circular RNA ciRS-7 accelerates ESCC progression through acting as a miR-876-5p sponge to enhance MAGE-A family expression” [Cancer Lett. 426 (2018) 37–46]	42
Sorbitol dehydrogenase induction of cancer cell necroptosis and macrophage polarization in the HCC microenvironment suppresses tumor progression	42
Active immunization with a structurally aggregated PD-L1 antigen breaks T and B immune tolerance in non-human primates and exhibits in vivo anti-tumoral effects in immunocompetent mouse tumor models	42
Non-muscle myosin II isoforms orchestrate substrate stiffness sensing to promote cancer cell contractility and migration	42
Corrigendum to “P-REX1 amplification promotes progression of cutaneous melanomavia the PAK1/P38/MMP-2 pathway” [Cancer Lett. 407 (2017) 66–75]	42
Low-dose metronomic chemotherapy triggers oxidized mtDNA sensing inside tumor cells to potentiate CD8+T anti-tumor immunity	42
Single-cell chemokine receptor profiles delineate the immune contexture of tertiary lymphoid structures in head and neck squamous cell carcinoma	42
LINC00978 regulates metabolic rewiring to promote the malignancy of glioblastoma through AKR1B1	42
PPAR agonists attenuate lenalidomide's anti-myeloma activity in vitro and in vivo	42
GPRC5A promotes gallbladder cancer metastasis by upregulating TNS4 via the JAK2–STAT3 pathway	41
Long noncoding RNA lnc-LEMGC combines with DNA-PKcs to suppress gastric cancer metastasis	41
Remodeling of tumor microenvironment by extracellular matrix protein 1a differentially regulates ovarian cancer metastasis	41
Gold nanoparticles and obese adipose tissue microenvironment in cancer treatment	41
Spermatid perinuclear RNA-binding protein promotes UBR5-mediated proteolysis of Dicer to accelerate triple-negative breast cancer progression	41
Retraction notice to “MicroRNA-19a and -19b regulate cervical carcinoma cell proliferation and invasion by targeting CUL5” [Canc. Lett. 322 (2012) 148–158]	41
Editorial Board	41
hnRNPLL regulates MYOF alternative splicing and correlates with early metastasis in pancreatic ductal adenocarcinoma	40
Decoding the potential microbiome modulation strategies from bugs to drugs in pancreatic cancer: Insights from clinical trials	40
Smoking-induced CCNA2 expression promotes lung adenocarcinoma tumorigenesis by boosting AT2/AT2-like cell differentiation	40
Early detection and intervention of clonal hematopoiesis for preventing hematological malignancies	40
Develop a Novel Therapy for Pancreatic Cancer	40
REDD1 is a determinant of the sensitivity of renal cell carcinoma cells to autophagy inhibition that can be therapeutically exploited by targeting PIM activity	40
Mucins as contrast agent targets for fluorescence-guided surgery of pancreatic cancer	39
Editorial Board	39
Phosphorylation of PBK/TOPK Tyr74 by JAK2 promotes Burkitt lymphoma tumor growth	39
Editorial Board	39
WD repeat protein 54-mediator of ErbB2-driven cell motility 1 axis promotes bladder cancer tumorigenesis and metastasis and impairs chemosensitivity	39
Editorial Board	39
Local delivery of optimized nanobodies targeting the PD-1/PD-L1 axis with a self-amplifying RNA viral vector induces potent antitumor responses	38
Exercise in cancer prevention and anticancer therapy: Efficacy, molecular mechanisms and clinical information	38
The safety and efficacy outcomes of Minnelide given alone or in combination with paclitaxel in advanced gastric cancer: A phase I trial	38
Fas signaling in adipocytes promotes low-grade inflammation and lung metastasis of colorectal cancer through interaction with Bmx	38
TRF2 cooperates with CTCF for controlling the oncomiR-193b-3p in colorectal cancer	37
Application prospect of circular RNA-based neoantigen vaccine in tumor immunotherapy	37
ZC3H13-mediated N6-methyladenosine modification of PHF10 is impaired by fisetin which inhibits the DNA damage response in pancreatic cancer	37
Mitochondrial fragmentation in liver cancer: Emerging player and promising therapeutic opportunities	37
The post-chemotherapy changes of tumor physical microenvironment: Targeting extracellular matrix to address chemoresistance	37
Radiotherapy-induced tumor physical microenvironment remodeling to overcome immunotherapy resistance	37
Phase separation of EEF1E1 promotes tumor stemness via PTEN/AKT-mediated DNA repair in hepatocellular carcinoma	37
Suppressive immune microenvironment and CART therapy for glioblastoma: Future prospects and challenges	37
CircUBE3A(2,3,4,5) promotes adenylate-uridylate-rich binding factor 1 nuclear translocation to suppress prostate cancer metastasis	37

Dysregulation of autophagy in gastric carcinoma: Pathways to tumor progression and resistance to therapy	37
Depression in breast cancer patients: Immunopathogenesis and immunotherapy	36
Frontiers in pancreatic cancer on biomarkers, microenvironment, and immunotherapy	36
Nanomaterials in crossroad of autophagy control in human cancers: Amplification of cell death mechanisms	36
Long noncoding RNA KB-1460A1.5 inhibits glioma tumorigenesis via miR-130a-3p/TSC1/mTOR/YY1 feedback loop	36
RNA binding protein RALY activates the cholesterol synthesis pathway through an MTA1 splicing switch in hepatocellular carcinoma	36
Pan-cancer atlas of tumor-resident microbiome, immunity and prognosis	36
Copper in hepatocellular carcinoma： A double-edged sword with therapeutic potentials	36
Corrigendum to “Scattered DUSP28 is a novel biomarker responsible for aggravating malignancy via the autocrine and paracrine signaling in metastatic pancreatic cancer” [Cancer Lett. 456 (2019 Aug 1) 1	35
Editorial Board	35
Editorial Board	35
A journey to excellence: Disseminating groundbreaking discoveries in oncology research	35
Corrigendum to “Helicobacter pylori upregulates Nanog and Oct4 via Wnt/β-catenin signaling pathway to promote cancer stem cell-like properties in human gastric cancer” [Canc. Lett. 374 (2016) 292–303]	35
Super-giant cells: Toward understanding tumor origins on the organismal level	35
Circadian disruption in cancer and regulation of cancer stem cells by circadian clock genes: An updated review	35
Identification of SMARCAL1 as a molecular target for small cell lung cancer treatment	35
Editorial Board	35
WITHDRAWN: Proteomic analysis of plasma-derived exosomes identifies biomarkers that distinguish brain and liver metastasis in lung cancer patients	35
PI3K PROTAC overcomes the lapatinib resistance in PIK3CA-mutant HER2 positive breast cancer	34
High-content drug screening in zebrafish xenografts reveals high efficacy of dual MCL-1/BCL-XL inhibition against Ewing sarcoma	34
Single-nucleus sequencing unveils heterogeneity in renal cell carcinomas microenvironment: Insights into pathogenic origins and treatment-responsive cellular subgroups	34
Aging of the progenitor cells that initiate prostate cancer	34
Targeted inhibition of CHKα and mTOR in models of pancreatic ductal adenocarcinoma: A novel regimen for metastasis	34
Dual targeting PPARα and NPC1L1 metabolic vulnerabilities blocks tumorigenesis	34
Emerging insights into origin and pathobiology of primary central nervous system lymphoma	34
CPSF3 regulates alternative polyadenylation of CNIH2 to promote esophageal squamous cell carcinoma progression	34
Unlocking c-MET: A comprehensive journey into targeted therapies for breast cancer	34
Corrigendum to “NSUN4 mediated RNA 5-methylcytosine promotes the malignant progression of glioma through improving the CDC42 mRNA stabilization” [Cancer Lett. (2024) 597 217059]	34
Single-cell transcriptomics reveals intratumor heterogeneity and the potential roles of cancer stem cells and myCAFs in colorectal cancer liver metastasis and recurrence	34
A novel GRK3-HDAC2 regulatory pathway is a key direct link between neuroendocrine differentiation and angiogenesis in prostate cancer progression	34
Disparities in mortality risk after diagnosis of hematological malignancies in 185 countries: A global data analysis	34
CRISPR/Cas9 screen reveals that targeting TRIM34 enhances ferroptosis sensitivity and augments immunotherapy efficacy in hepatocellular carcinoma	33
Cancer-associated fibroblasts activated by miR-196a promote the migration and invasion of lung cancer cells	33
Lipid metabolism reprogramming of CD8+ T cell and therapeutic implications in cancer	33
The mitotic regulator RCC2 promotes glucose metabolism through BACH1-dependent transcriptional upregulation of hexokinase II in glioma	33
Revisiting the advances and challenges in the clinical applications of extracellular vesicles in cancer	33
EDARADD promotes colon cancer progression by suppressing E3 ligase Trim21-mediated ubiquitination and degradation of Snail	33
SLC7A11/ xCT is a target of miR-5096 and its restoration partially rescues miR-5096-mediated ferroptosis and anti-tumor effects in human breast cancer cells	33
Letter to the editor regarding “Dual blockade of EGFR and CDK4/6 delays head and neck squamous cell carcinoma progression by inducing metabolic rewiring."	33
E2F1 promotes proliferation and metastasis of clear cell renal cell carcinoma via activation of SREBP1-dependent fatty acid biosynthesis	33
Deciphering the tumor-suppressive role of PSMB9 in melanoma through multi-omics and single-cell transcriptome analyses	33
Editorial Board	32
LncRNA-miRNA axes in breast cancer: Novel points of interaction for strategic attack	32
Targeting tumor-intrinsic SLC16A3 to enhance anti-PD-1 efficacy via tumor immune microenvironment reprogramming	32
Editorial Board	32
Editorial Board	32
Biodistribution and therapeutic efficacy of a gold nanoparticle-based targeted drug delivery system against pancreatic cancer	32
Identification of SPP1+ macrophages in promoting cancer stemness via vitronectin and CCL15 signals crosstalk in liver cancer	32
Editorial Board	32
IgSF protein EWI2 is a tumor suppressor	32
Histone lactylation dynamics: Unlocking the triad of metabolism, epigenetics, and immune regulation in metastatic cascade of pancreatic cancer	32
The eIF3a translational control axis in the Wnt/β-catenin signaling pathway and colon tumorigenesis	32
Editorial Board	32
TFAP2C-DDR1 axis regulates resistance to CDK4/6 inhibitor in breast cancer	31
The nuclear condensates of ESE3/EHF induce cellular senescence without the associated inflammatory secretory phenotype in pancreatic ductal adenocarcinoma	31
Editorial Board	31
A novel microenvironment regulated system CAR-T (MRS.CAR-T) for immunotherapeutic treatment of esophageal squamous carcinoma	31
Extracellular vesicle biomarkers redefine prostate cancer radiotherapy	31
The intersections between neuroscience and medulloblastoma	31
Confusion about the article: Natural product triptolide induces GSDME-mediated pyroptosis in head and neck cancer through suppressing mitochondrial hexokinase-ΙΙ	31
Cancer-associated fibroblast-like fibroblasts in vocal fold leukoplakia suppress CD8+T cell functions by inducing IL-6 autocrine loop and interacting with Th17 cells	31
PPDPF promotes esophageal squamous cell carcinoma progression by blocking PCCA binding to PCCB and inhibiting methionine catabolism	31
AXL signal mediates adaptive resistance to KRAS G12C inhibitors in KRAS G12C-mutant tumor cells	31
Significance of longitudinal Epstein–Barr virus DNA combined with multipoint tumor response for dynamic risk stratification and treatment adaptation in nasopharyngeal carcinoma	31
CHEK2 deficiency increase the response to PD-1 inhibitors by affecting the tumor immune microenvironment	31
The new era of pancreatic cancer treatment: Application of nanotechnology breaking through bottlenecks	30
Harnessing genetic interactions for prediction of immune checkpoint inhibitors response signature in cancer cells	30
The novel long noncoding RNA AU021063, induced by IL-6/Arid5a signaling, exacerbates breast cancer invasion and metastasis by stabilizing Trib3 and activating the Mek/Erk pathway	30
Inhibition of the endosomal recycling pathway downregulates HER2 activation and overcomes resistance to tyrosine kinase inhibitors in HER2-positive breast cancer	30
circCCNY enhances lenvatinib sensitivity and suppresses immune evasion in hepatocellular carcinoma by serving as a scaffold for SMURF1 mediated HSP60 degradation	30
Cancer-associated fibroblasts: A key target to snatch victory from defeat in therapy resistance associated with the pancreatic cancer stroma	30
Magnolin targeting of the JNK/Sp1/MMP15 signaling axis suppresses cervical cancer microenvironment and metastasis via microbiota modulation	30
ITGB5 facilitates gastric cancer metastasis by promoting TGFBR2 endosomal recycling	30
Mutant IDH1 promotes phagocytic function of microglia/macrophages in gliomas by downregulating ICAM1	30
Loss of ASAP1 in the MMTV-PyMT model of luminal breast cancer activates AKT, accelerates tumorigenesis, and promotes metastasis	30
IDO1/TDO dual inhibitor RY103 targets Kyn-AhR pathway and exhibits preclinical efficacy on pancreatic cancer	30
Targeting the molecular chaperone CCT2 inhibits GBM progression by influencing KRAS stability	30
Evolution and contemporary role of metronomic chemotherapy in the treatment of neuroblastoma	30
Tumor-derived extracellular vesicles induce invalid cytokine release and exhaustion of CD19 CAR-T Cells	30
GALNT3 suppresses lung cancer by inhibiting myeloid-derived suppressor cell infiltration and angiogenesis in a TNFR and c-MET pathway-dependent manner	29
The transformation of cancer-associated fibroblasts: Current perspectives on the role of TGF-β in CAF mediated tumor progression and therapeutic resistance	29
Deciphering the immune modulation through deep transcriptomic profiling and therapeutic implications of DNA damage repair pattern in hepatocellular carcinoma	29
Multi-functional extracellular vesicles: Potentials in cancer immunotherapy	29
Inflammatory cytokine-regulated LNCPTCTS suppresses thyroid cancer progression via enhancing Snail nuclear export	29
Metformin inhibits neutrophil extracellular traps-promoted pancreatic carcinogenesis in obese mice	29
Disruption of enhancer-driven S100A14 expression promotes esophageal carcinogenesis	29
A novel role of TGFBI in macrophage polarization and macrophage-induced pancreatic cancer growth and therapeutic resistance	29
A foundation model with weak experiential guidance in detecting muscle invasive bladder cancer on MRI	29
HMGB1 in the interplay between autophagy and apoptosis in cancer	29
Statin in combination with cisplatin makes favorable tumor-immune microenvironment for immunotherapy of head and neck squamous cell carcinoma	29
ITPR1-AS1 promotes small cell lung cancer metastasis by facilitating P21 splicing and stabilizing DDX3X to activate the cRaf-MEK-ERK cascade	29
Proteolysis of a histone acetyl reader, ATAD2, induces chemoresistance of cancer cells under severe hypoxia by inhibiting cell cycle progression in S phase	29
Cope with copper: From copper linked mechanisms to copper-based clinical cancer therapies	29
N-methyladenosine enhances the expression of TGF-β-SMAD signaling family to inhibit cell growth and promote cell metastasis	28
Novel SERCA2 inhibitor Diphyllin displays anti-tumor effect in non-small cell lung cancer by promoting endoplasmic reticulum stress and mitochondrial dysfunction	28