Cancer Letters

Papers
(The TQCC of Cancer Letters is 19. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
MDSCs in bone metastasis: Mechanisms and therapeutic potential320
Targeting MKK3/c-Myc interaction to overcome osimertinib acquired resistance in EGFR mutant lung cancer193
Corrigendum to “Inhibition of Aurora kinases induces apoptosis and autophagy via AURKB/p70S6K/RPL15 axis in human leukemia cells” [Cancer. Lett. (382) 2016-11-28; 382(2):215–230]171
The landscape of malignant transition: Unraveling cancer cell-of-origin and heterogeneous tissue microenvironment168
Chaperone directed heterobifunctional molecules circumvent KRASG12C inhibitor resistance153
METTL3 regulates M6A methylation-modified EBV-pri-miR-BART3-3p to promote NK/T cell lymphoma growth153
A novel mismatch repair deficient lung adenocarcinoma model for immunotherapy research132
Corrigendum to “Selective degradation of FGFR1/2 overcomes antiestrogen resistance in ER+ breast cancer with FGFR1/2 alterations” [619 1 (2025) 217668 1–13]126
LCAT deficiency promotes hepatocellular carcinoma progression and lenvatinib resistance by promoting triglyceride catabolism and fatty acid oxidation122
CD147-specific chimeric antigen receptor T cells effectively inhibit T cell acute lymphoblastic leukemia119
Editorial Board117
Combination treatment with 17β-estradiol and anti-PD-L1 suppresses MC38 tumor growth by reducing PD-L1 expression and enhancing M1 macrophage population in MC38 colon tumor model116
Coiled-coil domain-containing 154 promotes colorectal cancer proliferation and metastasis via interacting with minichromosome maintenance complex component 2112
Hormonal and neuronal interactions shaping the brain metastatic microenvironment111
Bypassing the Tollway; a novel path to TLR4 independent stemness regulation110
Versatility of Exosomes for Cancer Therapy110
IBI379, a novel B cell maturation antigen/CD3 bispecific T-cell engager, displays high antitumor efficacy in preclinical models of multiple myeloma107
Ethnic Diversity and Metabolic Variations in Ovarian Cancer Cells: Implications for Personalized Medicine Strategies106
Metronomic chemotherapy regimens and targeted therapies in non-Hodgkin lymphoma: The best of two worlds105
Editorial Board104
The E3 ligase TRIM22 functions as a tumor suppressor in breast cancer by targeting CCS for proteasomal degradation to inhibit STAT3 signaling101
KAT7 enhances the proliferation and metastasis of head and neck squamous carcinoma by promoting the acetylation level of LDHA97
Nervous system in colorectal cancer96
Evaluation and preservation of fertility in patients with hematologic malignancies94
Understanding the significance of biological clock and its impact on cancer incidence94
Targeting LINC01607 sensitizes hepatocellular carcinoma to Lenvatinib via suppressing mitophagy89
Increasing membrane polyunsaturated fatty acids sensitizes non-small cell lung cancer to anti-PD-1/PD-L1 immunotherapy86
Proteomics and single cell profiling identify keratin driven preexisting immunity influences lung squamous carcinoma neoadjuvant therapy86
Novel role of MKRN2 in regulating tumor growth through host microenvironment and macrophage M1 to M2 switch85
Accelerating the clinical translation of CD70-targeted chimeric antigen receptor-based cell therapies in oncology: A comprehensive clinical investigation panorama analysis based on the Trialtrove data85
Regulation of gut microbiota on immune cell ferroptosis: A novel insight for immunotherapy against tumor84
Targeting p53 for immune modulation: Exploring its functions in tumor immunity and inflammation84
Targeted inhibition of the expression of both MCM5 and MCM7 by miRNA-214 impedes DNA replication and tumorigenesis in hepatocellular carcinoma cells82
Selpercatinib mitigates cancer cachexia independent of anti-tumor activity in the HT1080 tumor model81
NSUN2-mediated m5C modification of KDM6B mRNA enhances osteoclast differentiation and promotes breast cancer bone metastasis80
Valproate and lithium: Old drugs for new pharmacological approaches in brain tumors?80
An emerging aspect of cancer neuroscience: A literature review on chemotherapy-induced peripheral neuropathy78
PI3K inhibitor impairs tumor progression and enhances sensitivity to anlotinib in anlotinib-resistant osteosarcoma73
The interplay between autophagy and apoptosis: its implication in lung cancer and therapeutics72
Clinical development of immuno-oncology therapeutics72
Comparable survival outcomes in HLA-Matched and haploidentical hematopoietic stem cell transplantation for severe aplastic anemia patients aged 40–50: A CBMTR Registry-based propensity score matching 71
PROTACs: Novel tools for improving immunotherapy in cancer71
Targeted inhibition of acidic nucleoplasmic DNA-binding protein 1 enhances radiosensitivity of non-small cell lung cancer71
A natural compound melatonin enhances the effects of Nimotuzumab via inhibiting EGFR in glioblastoma71
Dual mTORC1/2 inhibitor AZD2014 diminishes myeloid-derived suppressor cells accumulation in ovarian cancer and delays tumor growth70
ASPH dysregulates cell death and induces chemoresistance in hepatocellular carcinoma70
Osteopontin promotes tumor microenvironment remodeling and therapy resistance69
Intratumoral injection of mRNA encoding survivin in combination with STAT3 inhibitor stattic enhances antitumor effects69
Unscheduled polyploidy synergizes with oncogenic mutations to enhance genome instability and tumorigenesis69
Sphingosine-1 phosphate receptor 1 (S1PR1) expression maintains stemness of acute myeloid leukemia stem cells68
ERBB3 targeting: A promising approach to overcoming cancer therapeutic resistance68
The role of Hippo/YAP1 in cancer-associated fibroblasts: Literature review and future perspectives67
Neoantigen discovery and applications in glioblastoma: An immunotherapy perspective65
TIM3 on natural killer cells regulates antibody-dependent cellular cytotoxicity in HER2-positive gastric cancer64
Hypoxia effects on glioblastoma progression through YAP/TAZ pathway regulation64
Tumor-targeted exosomes for delivery of anticancer drugs63
The stromal microenvironment endows pancreatic neuroendocrine tumors with spatially specific invasive and metastatic phenotypes61
FAP upregulates PD-L1 expression in cancer-associated fibroblasts to exacerbate T cells dysfunction and suppress anti-tumor immunity61
Sialic Acids: Sweet modulators fueling cancer cells and domesticating the tumor microenvironment61
M6A-modified lncRNA FAM83H-AS1 promotes colorectal cancer progression through PTBP161
CSNK2A1 confers gemcitabine resistance to pancreatic ductal adenocarcinoma via inducing autophagy60
Tuning cellular metabolism for cancer virotherapy59
Integrated analysis of ascites and plasma extracellular vesicles identifies a miRNA-based diagnostic signature in ovarian cancer59
CD155 in tumor progression and targeted therapy59
MicroRNA-21 deficiency suppresses prostate cancer progression through downregulation of the IRS1-SREBP-1 signaling pathway59
The combination of gemcitabine plus an anti-FGFR inhibitor can have a synergistic antitumor effect on FGF-activating cholangiocarcinoma59
Letter to the editor on ‘A deep neural network predictor to predict the sensitivity of neoadjuvant chemoradiotherapy in locally advanced rectal cancer’59
Fatty acids in cancer chemoresistance59
Sonrotoclax (BGB-11417) synergistically amplifies the radiotherapy-elicited anti-tumor immune response58
MLCK inhibition induces synthetic lethality in MYC-driven cancer57
R-spondin-3 promotes proliferation and invasion of breast cancer cells independently of Wnt signaling57
Targeting Amino Acid Dependency for Cancer Treatment56
Inhibition of T-antigen expression promoting glycogen synthase kinase 3 impairs merkel cell carcinoma cell growth56
Corrigendum to “Discovery of YH677 as a cancer stemness inhibitor that suppresses triple-negative breast cancer growth and metastasis by regulating the TGFβ signaling pathway” [Canc. Lett. (2023) 216155
FOXF2 expression triggered by endocrine therapy orchestrates therapeutic resistance through reorganization of chromatin architecture in breast cancer54
Advancing neoadjuvant therapy with inetetamab for HER2-Positive breast cancer54
Conquering chemoresistance in pancreatic cancer: Exploring novel drug therapies and delivery approaches amidst desmoplasia and hypoxia53
ANKZF1 knockdown inhibits glioblastoma progression by promoting intramitochondrial protein aggregation through mitoRQC53
Identification and characterization of Bufalin as a novel EGFR degrader53
S100A6 drives lymphatic metastasis of liver cancer via activation of the RAGE/NF-kB/VEGF-D pathway53
BCL-2/BCL-XL dual inhibition triggers Gasdermin D-mediated pyroptosis in mantle cell lymphoma53
Plasmacytoid dendritic cells recruited by HIF-1α/eADO/ADORA1 signaling induce immunosuppression in hepatocellular carcinoma53
Glucose restriction induces ROS-AMPK-mediated CTR1 expression and increases cisplatin efficiency in NSCLC53
Corrigendum to “UBE2T promotes radiation resistance in non-small cell lung cancer via inducing epithelial-mesenchymal transition and the ubiquitination-mediated FOXO1 degradation” [Canc. Lett. 494 (2053
Mapping the tumor immune landscape: single-cell RNA sequencing in cancer immunotherapy52
Lactylation-boosted polycomb repression of KLF4 elicits glycolysis in retinoblastoma: A positive feedback circuit between histone modifications52
A high-affinity antibody-drug conjugates Actuximab-MMAE for potent and selective targeting of CEACAM5-Positive tumors52
Obese adipose tissue-derived extracellular vesicles enriched with glycolytic cargo promote colorectal cancer tumorigenesis51
Claudin-1 interacts with EPHA2 to promote cancer stemness and chemoresistance in colorectal cancer51
CircFLNB upregulated by chemotherapy via alternative splicing suppresses the progression of colorectal cancer51
Tumor-derived miR-378a-3p-containing extracellular vesicles promote osteolysis by activating the Dyrk1a/Nfatc1/Angptl2 axis for bone metastasis51
Deubiquitinating PABPC1 by USP10 upregulates CLK2 translation to promote tumor progression in pancreatic ductal adenocarcinoma51
Emerging roles of lysosome homeostasis (repair, lysophagy and biogenesis) in cancer progression and therapy50
Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastases50
LKB1 inhibits telomerase activity resulting in cellular senescence through histone lactylation in lung adenocarcinoma50
Overexpression of nucleotide metabolic enzyme DUT in hepatocellular carcinoma potentiates a therapeutic opportunity through targeting its dUTPase activity49
Copper Orchestrates Triple-negative Breast Cancer Progression via the STEAP3-dependent CDK16-JAK1 Activation49
Improved antitumor effects elicited by an oncolytic HSV-1 expressing a novel B7H3nb/CD3 BsAb49
The intratumoral microbiome: Characterization methods and functional impact49
Nanoparticles in the diagnosis and treatment of cancer metastases: Current and future perspectives49
Corrigendum to “P-REX1 amplification promotes progression of cutaneous melanomavia the PAK1/P38/MMP-2 pathway” [Cancer Lett. 407 (2017) 66–75]48
An effective two-stage NMBzA-induced rat esophageal tumor model revealing that the FAT-Hippo-YAP1 axis drives the progression of ESCC48
Long noncoding RNA lnc-LEMGC combines with DNA-PKcs to suppress gastric cancer metastasis48
MEK-mediated CHPF2 phosphorylation promotes colorectal cancer cell proliferation and metastasis by activating NF-κB signaling48
Remodeling of tumor microenvironment by extracellular matrix protein 1a differentially regulates ovarian cancer metastasis47
Editorial Board47
Corrigendum to “Circular RNA ciRS-7 accelerates ESCC progression through acting as a miR-876-5p sponge to enhance MAGE-A family expression” [Cancer Lett. 426 (2018) 37–46]47
Mucins as contrast agent targets for fluorescence-guided surgery of pancreatic cancer47
Long noncoding RNA KB-1460A1.5 inhibits glioma tumorigenesis via miR-130a-3p/TSC1/mTOR/YY1 feedback loop47
Editorial Board47
DAB2IP suppresses tumor malignancy by inhibiting GRP75-driven p53 ubiquitination in colon cancer47
LINC00978 regulates metabolic rewiring to promote the malignancy of glioblastoma through AKR1B147
Develop a Novel Therapy for Pancreatic Cancer46
Spermatid perinuclear RNA-binding protein promotes UBR5-mediated proteolysis of Dicer to accelerate triple-negative breast cancer progression46
Editorial Board45
PPAR agonists attenuate lenalidomide's anti-myeloma activity in vitro and in vivo45
Editorial Board45
WEE1 confers resistance to KRASG12C inhibitors in non-small cell lung cancer44
Decoding the potential microbiome modulation strategies from bugs to drugs in pancreatic cancer: Insights from clinical trials44
Application prospect of circular RNA-based neoantigen vaccine in tumor immunotherapy44
The post-chemotherapy changes of tumor physical microenvironment: Targeting extracellular matrix to address chemoresistance44
Multi-omics analysis unraveling stemness features associated with oncogenic dedifferentiation in 12 cancers44
Functional genomic approaches in acute myeloid leukemia: Insights into disease models and the therapeutic potential of reprogramming44
A novel molecular subtyping based on multi-omics analysis for prognosis predicting in colorectal melanoma: A 16-year prospective multicentric study44
Interplay among extracellular vesicles, cancer stemness and immune regulation in driving hepatocellular carcinoma progression44
Novel SARS-CoV-2 inhibition properties of the anti-cancer Kang Guan Recipe herbal formula44
The safety and efficacy outcomes of Minnelide given alone or in combination with paclitaxel in advanced gastric cancer: A phase I trial44
FUT2-dependent fucosylation of LAMP1 promotes the apoptosis of colorectal cancer cells by regulating the autophagy-lysosomal pathway43
Smoking-induced CCNA2 expression promotes lung adenocarcinoma tumorigenesis by boosting AT2/AT2-like cell differentiation43
Low-dose metronomic chemotherapy triggers oxidized mtDNA sensing inside tumor cells to potentiate CD8+T anti-tumor immunity43
CircUBE3A(2,3,4,5) promotes adenylate-uridylate-rich binding factor 1 nuclear translocation to suppress prostate cancer metastasis43
Gold nanoparticles and obese adipose tissue microenvironment in cancer treatment43
hnRNPLL regulates MYOF alternative splicing and correlates with early metastasis in pancreatic ductal adenocarcinoma42
GPRC5A promotes gallbladder cancer metastasis by upregulating TNS4 via the JAK2–STAT3 pathway42
Dysregulation of autophagy in gastric carcinoma: Pathways to tumor progression and resistance to therapy42
Mitochondrial fragmentation in liver cancer: Emerging player and promising therapeutic opportunities42
Single-cell chemokine receptor profiles delineate the immune contexture of tertiary lymphoid structures in head and neck squamous cell carcinoma41
ZC3H13-mediated N6-methyladenosine modification of PHF10 is impaired by fisetin which inhibits the DNA damage response in pancreatic cancer41
Comprehensive clinico-genomic analysis of pancreatic ductal adenocarcinoma: overcoming biases and limitations41
TRF2 cooperates with CTCF for controlling the oncomiR-193b-3p in colorectal cancer41
Treatment strategies and molecular mechanism of radiotherapy combined with immunotherapy in colorectal cancer41
Copper in hepatocellular carcinoma: A double-edged sword with therapeutic potentials41
The feedback loop of AURKA/DDX5/TMEM147-AS1/let-7 drives lipophagy to induce cisplatin resistance in epithelial ovarian cancer41
Single-cell RNA-sequencing of human spleens reveals an IDO-1+ tolerogenic dendritic cell subset in pancreatic cancer patients that is absent in normal individuals41
AI-based radiomic features predict outcomes and the added benefit of chemoimmunotherapy over chemotherapy in extensive stage small cell lung cancer: A multi-institutional study41
Circular RNA circPFKP promotes cell proliferation by activating IMPDH2 in prostate cancer41
Non-muscle myosin II isoforms orchestrate substrate stiffness sensing to promote cancer cell contractility and migration41
Protective role of epithelial deoxyhypusine synthase in colorectal carcinogenesis caused by deletion of the adenomatous polyposis coli gene40
Early detection and intervention of clonal hematopoiesis for preventing hematological malignancies40
REDD1 is a determinant of the sensitivity of renal cell carcinoma cells to autophagy inhibition that can be therapeutically exploited by targeting PIM activity40
Depression in breast cancer patients: Immunopathogenesis and immunotherapy40
Pan-cancer atlas of tumor-resident microbiome, immunity and prognosis40
WD repeat protein 54-mediator of ErbB2-driven cell motility 1 axis promotes bladder cancer tumorigenesis and metastasis and impairs chemosensitivity40
Human mesenchymal stromal cells maintain their stem cell traits after high-LET particle irradiation – Potential implications for particle radiotherapy and manned space missions40
Fas signaling in adipocytes promotes low-grade inflammation and lung metastasis of colorectal cancer through interaction with Bmx40
Exercise in cancer prevention and anticancer therapy: Efficacy, molecular mechanisms and clinical information40
Nanomaterials in crossroad of autophagy control in human cancers: Amplification of cell death mechanisms40
Tumor-nerve interactions in cancer regulation and progression40
Phase separation of EEF1E1 promotes tumor stemness via PTEN/AKT-mediated DNA repair in hepatocellular carcinoma39
SENP1-Sirt3 axis promotes cholesterol biosynthesis in tumor-associated macrophages to suppress anti-tumor immunity39
Targeting WEE1 kinase as a therapeutic strategy in ATIP3-deficient breast cancers39
Shifts in cancer funding: An overview of terminated research grants at the national cancer institute39
Radiotherapy-induced tumor physical microenvironment remodeling to overcome immunotherapy resistance39
Sorbitol dehydrogenase induction of cancer cell necroptosis and macrophage polarization in the HCC microenvironment suppresses tumor progression39
Suppressive immune microenvironment and CART therapy for glioblastoma: Future prospects and challenges38
Frontiers in pancreatic cancer on biomarkers, microenvironment, and immunotherapy38
Phosphorylation of PBK/TOPK Tyr74 by JAK2 promotes Burkitt lymphoma tumor growth38
Identification of SMARCAL1 as a molecular target for small cell lung cancer treatment38
Local delivery of optimized nanobodies targeting the PD-1/PD-L1 axis with a self-amplifying RNA viral vector induces potent antitumor responses38
Active immunization with a structurally aggregated PD-L1 antigen breaks T and B immune tolerance in non-human primates and exhibits in vivo anti-tumoral effects in immunocompetent mouse tumor models38
RNA binding protein RALY activates the cholesterol synthesis pathway through an MTA1 splicing switch in hepatocellular carcinoma38
Effective leukemia-to-granulocyte induction by a cocktail of RUNX1, SPI1 and CEBPE37
CPSF3 regulates alternative polyadenylation of CNIH2 to promote esophageal squamous cell carcinoma progression37
Lipid metabolism reprogramming of CD8+ T cell and therapeutic implications in cancer37
Targeting tumor-intrinsic SLC16A3 to enhance anti-PD-1 efficacy via tumor immune microenvironment reprogramming37
SLC7A11/ xCT is a target of miR-5096 and its restoration partially rescues miR-5096-mediated ferroptosis and anti-tumor effects in human breast cancer cells37
Deciphering the tumor-suppressive role of PSMB9 in melanoma through multi-omics and single-cell transcriptome analyses37
Corrigendum to “NSUN4 mediated RNA 5-methylcytosine promotes the malignant progression of glioma through improving the CDC42 mRNA stabilization” [Cancer Lett. (2024) 597 217059]37
Single-cell transcriptomics reveals intratumor heterogeneity and the potential roles of cancer stem cells and myCAFs in colorectal cancer liver metastasis and recurrence37
Revisiting the advances and challenges in the clinical applications of extracellular vesicles in cancer37
Editorial Board36
Targeted inhibition of CHKα and mTOR in models of pancreatic ductal adenocarcinoma: A novel regimen for metastasis36
Corrigendum to “Helicobacter pylori upregulates Nanog and Oct4 via Wnt/β-catenin signaling pathway to promote cancer stem cell-like properties in human gastric cancer” [Canc. Lett. 374 (2016) 292–303]36
A journey to excellence: Disseminating groundbreaking discoveries in oncology research36
Corrigendum to “Scattered DUSP28 is a novel biomarker responsible for aggravating malignancy via the autocrine and paracrine signaling in metastatic pancreatic cancer” [Cancer Lett. 456 (2019 Aug 1) 136
Letter to the editor regarding “Dual blockade of EGFR and CDK4/6 delays head and neck squamous cell carcinoma progression by inducing metabolic rewiring."36
Dual targeting PPARα and NPC1L1 metabolic vulnerabilities blocks tumorigenesis36
Super-giant cells: Toward understanding tumor origins on the organismal level36
WITHDRAWN: Proteomic analysis of plasma-derived exosomes identifies biomarkers that distinguish brain and liver metastasis in lung cancer patients36
Keloids revisited: Current concepts in treatment and differential diagnosis35
A novel GRK3-HDAC2 regulatory pathway is a key direct link between neuroendocrine differentiation and angiogenesis in prostate cancer progression35
Circadian disruption in cancer and regulation of cancer stem cells by circadian clock genes: An updated review35
Biodistribution and therapeutic efficacy of a gold nanoparticle-based targeted drug delivery system against pancreatic cancer35
RNA methyltransferase METTL16: From molecular mechanisms to therapeutic prospects in cancers35
Single-nucleus sequencing unveils heterogeneity in renal cell carcinomas microenvironment: Insights into pathogenic origins and treatment-responsive cellular subgroups35
Disparities in mortality risk after diagnosis of hematological malignancies in 185 countries: A global data analysis35
The eIF3a translational control axis in the Wnt/β-catenin signaling pathway and colon tumorigenesis35
Deglycosylated PD-L1 is a biomarker for immune checkpoint blockade response: a real-world study in breast cancer patients in Taiwan35
Histone lactylation dynamics: Unlocking the triad of metabolism, epigenetics, and immune regulation in metastatic cascade of pancreatic cancer35
Enhanced prediction of breast cancer patient response to chemotherapy by integrating deconvolved expression patterns of immune, stromal and tumor cells35
PI3K PROTAC overcomes the lapatinib resistance in PIK3CA-mutant HER2 positive breast cancer34
SIK1 promotes ferroptosis resistance in pancreatic cancer via HDAC5-STAT6-SLC7A11 axis34
Identification of SPP1+ macrophages in promoting cancer stemness via vitronectin and CCL15 signals crosstalk in liver cancer34
Inflammatory cytokine-regulated LNCPTCTS suppresses thyroid cancer progression via enhancing Snail nuclear export34
CRISPR/Cas9 screen reveals that targeting TRIM34 enhances ferroptosis sensitivity and augments immunotherapy efficacy in hepatocellular carcinoma34
Unlocking c-MET: A comprehensive journey into targeted therapies for breast cancer34
TFAP2C-DDR1 axis regulates resistance to CDK4/6 inhibitor in breast cancer34
CHEK2 deficiency increase the response to PD-1 inhibitors by affecting the tumor immune microenvironment34
High-content drug screening in zebrafish xenografts reveals high efficacy of dual MCL-1/BCL-XL inhibition against Ewing sarcoma34
EDARADD promotes colon cancer progression by suppressing E3 ligase Trim21-mediated ubiquitination and degradation of Snail34
ITPR1-AS1 promotes small cell lung cancer metastasis by facilitating P21 splicing and stabilizing DDX3X to activate the cRaf-MEK-ERK cascade34
The mitotic regulator RCC2 promotes glucose metabolism through BACH1-dependent transcriptional upregulation of hexokinase II in glioma34
Inhibition of the endosomal recycling pathway downregulates HER2 activation and overcomes resistance to tyrosine kinase inhibitors in HER2-positive breast cancer33
A novel microenvironment regulated system CAR-T (MRS.CAR-T) for immunotherapeutic treatment of esophageal squamous carcinoma33
Editorial Board33
Significance of longitudinal Epstein–Barr virus DNA combined with multipoint tumor response for dynamic risk stratification and treatment adaptation in nasopharyngeal carcinoma33
Editorial Board33
IgSF protein EWI2 is a tumor suppressor33
Editorial Board33
Editorial Board33
Dual blockade of PD-1 and CTLA-4 generates long-lasting immunity against irradiated glioblastoma33
Editorial Board33
Editorial Board33
Loss of ASAP1 in the MMTV-PyMT model of luminal breast cancer activates AKT, accelerates tumorigenesis, and promotes metastasis33
Harnessing genetic interactions for prediction of immune checkpoint inhibitors response signature in cancer cells33
Radiosensitization of intrahepatic cholangiocarcinoma and metastatic disease in the liver using microbubble cavitation: results from a phase 2 clinical trial32
Targeting the molecular chaperone CCT2 inhibits GBM progression by influencing KRAS stability32
Magnolin targeting of the JNK/Sp1/MMP15 signaling axis suppresses cervical cancer microenvironment and metastasis via microbiota modulation32
Cancer-associated fibroblasts: A key target to snatch victory from defeat in therapy resistance associated with the pancreatic cancer stroma32
Proteolysis of a histone acetyl reader, ATAD2, induces chemoresistance of cancer cells under severe hypoxia by inhibiting cell cycle progression in S phase32
Confusion about the article: Natural product triptolide induces GSDME-mediated pyroptosis in head and neck cancer through suppressing mitochondrial hexokinase-ΙΙ32
Cancer-associated fibroblast-like fibroblasts in vocal fold leukoplakia suppress CD8+T cell functions by inducing IL-6 autocrine loop and interacting with Th17 cells32
PPDPF promotes esophageal squamous cell carcinoma progression by blocking PCCA binding to PCCB and inhibiting methionine catabolism31
Disruption of enhancer-driven S100A14 expression promotes esophageal carcinogenesis31
Cancer stem cells and tumor-associated macrophages: Interactions and therapeutic opportunities31
A two-stage genome-wide association study to identify novel genetic loci associated with irAEs in lung cancer patients received PD-1/PD-L1 inhibitors31
Statin in combination with cisplatin makes favorable tumor-immune microenvironment for immunotherapy of head and neck squamous cell carcinoma31
ITGB5 facilitates gastric cancer metastasis by promoting TGFBR2 endosomal recycling31
IDO1/TDO dual inhibitor RY103 targets Kyn-AhR pathway and exhibits preclinical efficacy on pancreatic cancer31
Cell adhesion molecule ITGB2 promotes CAR-T cell therapy in B-cell malignancies31
AXL signal mediates adaptive resistance to KRAS G12C inhibitors in KRAS G12C-mutant tumor cells31
The nuclear condensates of ESE3/EHF induce cellular senescence without the associated inflammatory secretory phenotype in pancreatic ductal adenocarcinoma31
Corrigendum to “Pharmacological inhibition of DUSP6 suppresses gastric cancer growth and metastasis and overcomes cisplatin resistance” [Cancer Lett. (2018) 412 243–255]31
Multi-functional extracellular vesicles: Potentials in cancer immunotherapy31
How to design next-generation of antibody-drug conjugates for cancer treatment: Lessons from unsuccessful clinical trials31
Editorial Board30
The pro-apoptotic peptide PEP-010 triggers apoptosis in pancreatic tumor models in monotherapy and in combination with gemcitabine independently of the KRAS status30
Mechanism of Resistance to a Phase-II Idelalisib-Based Clinical Trial in CLL30
HMGB1 in the interplay between autophagy and apoptosis in cancer30
The mammalian Sterile 20-like kinase 4 (MST4) signaling in tumor progression: Implications for therapy30
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