Cancer Letters

Article	Citations
Editorial Board	185
Unscheduled polyploidy synergizes with oncogenic mutations to enhance genome instability and tumorigenesis	174
Selpercatinib mitigates cancer cachexia independent of anti-tumor activity in the HT1080 tumor model	164
Sphingosine-1 phosphate receptor 1 (S1PR1) expression maintains stemness of acute myeloid leukemia stem cells	163
A novel mismatch repair deficient lung adenocarcinoma model for immunotherapy research	157
Versatility of Exosomes for Cancer Therapy	148
Bypassing the Tollway; a novel path to TLR4 independent stemness regulation	143
IBI379, a novel B cell maturation antigen/CD3 bispecific T-cell engager, displays high antitumor efficacy in preclinical models of multiple myeloma	142
Ethnic Diversity and Metabolic Variations in Ovarian Cancer Cells: Implications for Personalized Medicine Strategies	131
Editorial Board	130
Tuning cellular metabolism for cancer virotherapy	126
An emerging aspect of cancer neuroscience: A literature review on chemotherapy-induced peripheral neuropathy	124
Hormonal and neuronal interactions shaping the brain metastatic microenvironment	112
Coiled-coil domain-containing 154 promotes colorectal cancer proliferation and metastasis via interacting with minichromosome maintenance complex component 2	104
Corrigendum to “Inhibition of Aurora kinases induces apoptosis and autophagy via AURKB/p70S6K/RPL15 axis in human leukemia cells” [Cancer. Lett. (382) 2016-11-28; 382(2):215–230]	103
Corrigendum to “Selective degradation of FGFR1/2 overcomes antiestrogen resistance in ER+ breast cancer with FGFR1/2 alterations” [619 1 (2025) 217668 1–13]	103
Corrigendum to “Identification of metastasis-associated proteins involved in gallbladder carcinoma metastasis by proteomic analysis and functional exploration of chloride intracellular channel 1” [Can	101
CD147-specific chimeric antigen receptor T cells effectively inhibit T cell acute lymphoblastic leukemia	101
Combination treatment with 17β-estradiol and anti-PD-L1 suppresses MC38 tumor growth by reducing PD-L1 expression and enhancing M1 macrophage population in MC38 colon tumor model	100
Neutrophil extracellular traps enhance platinum resistance in ovarian cancer via SHP-1 activation	99
Dual role of LY96 in shaping the mesenchymal glioblastoma ecosystem through stem cell maintenance and macrophage MES-like reprogramming	97
Targeting FOXM1 reshapes antitumor immunity to attenuate small cell lung cancer progression	95
Valproate and lithium: Old drugs for new pharmacological approaches in brain tumors?	91
Targeting LINC01607 sensitizes hepatocellular carcinoma to Lenvatinib via suppressing mitophagy	89
Osteopontin promotes tumor microenvironment remodeling and therapy resistance	89

The stromal microenvironment endows pancreatic neuroendocrine tumors with spatially specific invasive and metastatic phenotypes	88
TIM3 on natural killer cells regulates antibody-dependent cellular cytotoxicity in HER2-positive gastric cancer	87
Intratumoral injection of mRNA encoding survivin in combination with STAT3 inhibitor stattic enhances antitumor effects	87
Hypoxia effects on glioblastoma progression through YAP/TAZ pathway regulation	86
A natural compound melatonin enhances the effects of Nimotuzumab via inhibiting EGFR in glioblastoma	85
NSUN2-mediated m5C modification of KDM6B mRNA enhances osteoclast differentiation and promotes breast cancer bone metastasis	85
The landscape of malignant transition: Unraveling cancer cell-of-origin and heterogeneous tissue microenvironment	82
Editorial Board	81
Sialic Acids: Sweet modulators fueling cancer cells and domesticating the tumor microenvironment	78
Nervous system in colorectal cancer	76
Accelerating the clinical translation of CD70-targeted chimeric antigen receptor-based cell therapies in oncology: A comprehensive clinical investigation panorama analysis based on the Trialtrove data	75
MDSCs in bone metastasis: Mechanisms and therapeutic potential	74
Integrated analysis of ascites and plasma extracellular vesicles identifies a miRNA-based diagnostic signature in ovarian cancer	74
Novel role of MKRN2 in regulating tumor growth through host microenvironment and macrophage M1 to M2 switch	73
LCAT deficiency promotes hepatocellular carcinoma progression and lenvatinib resistance by promoting triglyceride catabolism and fatty acid oxidation	73
ASPH dysregulates cell death and induces chemoresistance in hepatocellular carcinoma	73
Chaperone directed heterobifunctional molecules circumvent KRASG12C inhibitor resistance	73
Manganese mediates nucleoplasm distribution of cGAS to enhance systemic antitumor immunity and drive abscopal effect	73
Tumor-targeted exosomes for delivery of anticancer drugs	72
CSNK2A1 confers gemcitabine resistance to pancreatic ductal adenocarcinoma via inducing autophagy	71
A Deep Learning Pathomic Signature Predicts Survival and Recurrence in Pancreatic Ductal Adenocarcinoma Independent of CA19-9	71
METTL3 regulates M6A methylation-modified EBV-pri-miR-BART3-3p to promote NK/T cell lymphoma growth	71
CD155 in tumor progression and targeted therapy	71
PI3K inhibitor impairs tumor progression and enhances sensitivity to anlotinib in anlotinib-resistant osteosarcoma	70
Proteomics and single cell profiling identify keratin driven preexisting immunity influences lung squamous carcinoma neoadjuvant therapy	69
The role of Hippo/YAP1 in cancer-associated fibroblasts: Literature review and future perspectives	68
Regulation of gut microbiota on immune cell ferroptosis: A novel insight for immunotherapy against tumor	67
PROTACs: Novel tools for improving immunotherapy in cancer	67
The E3 ligase TRIM22 functions as a tumor suppressor in breast cancer by targeting CCS for proteasomal degradation to inhibit STAT3 signaling	64
Targeting MKK3/c-Myc interaction to overcome osimertinib acquired resistance in EGFR mutant lung cancer	64
Evaluation and preservation of fertility in patients with hematologic malignancies	64
Corrigendum to “The deficiency of ALKBH5 promotes lenvatinib resistance and CD8+ T cell exhaustion via accumulation of the cholesterol metabolite 27HC in hepatocellular carcinoma” [643 10 (2026) 21831	64
KAT7 enhances the proliferation and metastasis of head and neck squamous carcinoma by promoting the acetylation level of LDHA	64
Neoantigen discovery and applications in glioblastoma: An immunotherapy perspective	63
Targeting p53 for immune modulation: Exploring its functions in tumor immunity and inflammation	63
Comparable survival outcomes in HLA-Matched and haploidentical hematopoietic stem cell transplantation for severe aplastic anemia patients aged 40–50: A CBMTR Registry-based propensity score matching	62
Clinical development of immuno-oncology therapeutics	61
M6A-modified lncRNA FAM83H-AS1 promotes colorectal cancer progression through PTBP1	61
Targeted inhibition of the expression of both MCM5 and MCM7 by miRNA-214 impedes DNA replication and tumorigenesis in hepatocellular carcinoma cells	61
FAP upregulates PD-L1 expression in cancer-associated fibroblasts to exacerbate T cells dysfunction and suppress anti-tumor immunity	61
Fatty acids in cancer chemoresistance	60
ERBB3 targeting: A promising approach to overcoming cancer therapeutic resistance	59
Increasing membrane polyunsaturated fatty acids sensitizes non-small cell lung cancer to anti-PD-1/PD-L1 immunotherapy	59
The interplay between autophagy and apoptosis: its implication in lung cancer and therapeutics	59
Identification and characterization of Bufalin as a novel EGFR degrader	59
Letter to the editor on ‘A deep neural network predictor to predict the sensitivity of neoadjuvant chemoradiotherapy in locally advanced rectal cancer’	58
Nanoparticles in the diagnosis and treatment of cancer metastases: Current and future perspectives	58
Conquering chemoresistance in pancreatic cancer: Exploring novel drug therapies and delivery approaches amidst desmoplasia and hypoxia	58
Deubiquitinating PABPC1 by USP10 upregulates CLK2 translation to promote tumor progression in pancreatic ductal adenocarcinoma	57
Tumor cell derived CCL20 exacerbates the immunosuppressive microenvironment by recruiting CCR6+ Tregs in pancreatic cancer	57

Glucose restriction induces ROS-AMPK-mediated CTR1 expression and increases cisplatin efficiency in NSCLC	57
Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastases	56
Emerging roles of lysosome homeostasis (repair, lysophagy and biogenesis) in cancer progression and therapy	56
An effective two-stage NMBzA-induced rat esophageal tumor model revealing that the FAT-Hippo-YAP1 axis drives the progression of ESCC	56
The combination of gemcitabine plus an anti-FGFR inhibitor can have a synergistic antitumor effect on FGF-activating cholangiocarcinoma	56
LKB1 inhibits telomerase activity resulting in cellular senescence through histone lactylation in lung adenocarcinoma	56
Claudin-1 interacts with EPHA2 to promote cancer stemness and chemoresistance in colorectal cancer	56
MEK-mediated CHPF2 phosphorylation promotes colorectal cancer cell proliferation and metastasis by activating NF-κB signaling	56
G6PD+CSV+ circulating tumor cells associated with portal vein tumor thrombus formation via EMT-ferroptosis crosstalk: a dual biomarker for therapeutic efficacy and prognosis prediction in hepatocellul	55
S100A6 drives lymphatic metastasis of liver cancer via activation of the RAGE/NF-kB/VEGF-D pathway	55
Overexpression of nucleotide metabolic enzyme DUT in hepatocellular carcinoma potentiates a therapeutic opportunity through targeting its dUTPase activity	54
MLCK inhibition induces synthetic lethality in MYC-driven cancer	54
Targeting Amino Acid Dependency for Cancer Treatment	54
A high-affinity antibody-drug conjugates Actuximab-MMAE for potent and selective targeting of CEACAM5-Positive tumors	54
Corrigendum to “Discovery of YH677 as a cancer stemness inhibitor that suppresses triple-negative breast cancer growth and metastasis by regulating the TGFβ signaling pathway” [Canc. Lett. (2023) 2161	53
Corrigendum to “UBE2T promotes radiation resistance in non-small cell lung cancer via inducing epithelial-mesenchymal transition and the ubiquitination-mediated FOXO1 degradation” [Canc. Lett. 494 (20	53
Loss of TFAM accelerates pentose phosphate pathway by unleashing G6PD oligomerization to drive hepatocarcinogenesis	53
Copper orchestrates triple-negative breast cancer progression via the STEAP3-dependent CDK16-JAK1 activation	52
R-spondin-3 promotes proliferation and invasion of breast cancer cells independently of Wnt signaling	52
Mapping the tumor immune landscape: single-cell RNA sequencing in cancer immunotherapy	52
FOXF2 expression triggered by endocrine therapy orchestrates therapeutic resistance through reorganization of chromatin architecture in breast cancer	52
BCL-2/BCL-XL dual inhibition triggers Gasdermin D-mediated pyroptosis in mantle cell lymphoma	51
Advancing neoadjuvant therapy with inetetamab for HER2-Positive breast cancer	51
Extrachromosomal DNA amplifications exhibit distinct molecular characteristics and prognostic implications in gastric cancer	51
Obese adipose tissue-derived extracellular vesicles enriched with glycolytic cargo promote colorectal cancer tumorigenesis	50
CircFLNB upregulated by chemotherapy via alternative splicing suppresses the progression of colorectal cancer	50
Lactylation-boosted polycomb repression of KLF4 elicits glycolysis in retinoblastoma: A positive feedback circuit between histone modifications	50
ANKZF1 knockdown inhibits glioblastoma progression by promoting intramitochondrial protein aggregation through mitoRQC	50
Validation of “SARS-CoV-2 mRNA vaccines sensitize tumors to immune checkpoint blockade” in an independent cohort of 4,407 patients	50
Develop a Novel Therapy for Pancreatic Cancer	49
Improved antitumor effects elicited by an oncolytic HSV-1 expressing a novel B7H3nb/CD3 BsAb	49
Editorial Board	49
Editorial Board	49
Sonrotoclax (BGB-11417) synergistically amplifies the radiotherapy-elicited anti-tumor immune response	49
Exosomal circUBR5 drives metastasis and chemoresistance in gastric signet-ring cell carcinoma by reprogramming cholesterol metabolism through the hsa-miR-1208/CYP19A1 axis and ACAT1 upregulation	48
Editorial Board	48
Sorbitol dehydrogenase induction of cancer cell necroptosis and macrophage polarization in the HCC microenvironment suppresses tumor progression	48
Spermatid perinuclear RNA-binding protein promotes UBR5-mediated proteolysis of Dicer to accelerate triple-negative breast cancer progression	47
Novel SARS-CoV-2 inhibition properties of the anti-cancer Kang Guan Recipe herbal formula	47
Early detection and intervention of clonal hematopoiesis for preventing hematological malignancies	47
Editorial Board	47
A novel molecular subtyping based on multi-omics analysis for prognosis predicting in colorectal melanoma: A 16-year prospective multicentric study	47
FUT2-dependent fucosylation of LAMP1 promotes the apoptosis of colorectal cancer cells by regulating the autophagy-lysosomal pathway	46
TRF2 cooperates with CTCF for controlling the oncomiR-193b-3p in colorectal cancer	46
CircUBE3A(2,3,4,5) promotes adenylate-uridylate-rich binding factor 1 nuclear translocation to suppress prostate cancer metastasis	46
Remodeling of tumor microenvironment by extracellular matrix protein 1a differentially regulates ovarian cancer metastasis	46
Multi-omics analysis unraveling stemness features associated with oncogenic dedifferentiation in 12 cancers	46
WEE1 confers resistance to KRASG12C inhibitors in non-small cell lung cancer	45
Nanomaterials in crossroad of autophagy control in human cancers: Amplification of cell death mechanisms	45
Decoding the potential microbiome modulation strategies from bugs to drugs in pancreatic cancer: Insights from clinical trials	45
Phosphorylation of PBK/TOPK Tyr74 by JAK2 promotes Burkitt lymphoma tumor growth	45
WD repeat protein 54-mediator of ErbB2-driven cell motility 1 axis promotes bladder cancer tumorigenesis and metastasis and impairs chemosensitivity	45
Depression in breast cancer patients: Immunopathogenesis and immunotherapy	45
Targeting WEE1 kinase as a therapeutic strategy in ATIP3-deficient breast cancers	45
PPAR agonists attenuate lenalidomide's anti-myeloma activity in vitro and in vivo	45
REDD1 is a determinant of the sensitivity of renal cell carcinoma cells to autophagy inhibition that can be therapeutically exploited by targeting PIM activity	44
Mucins as contrast agent targets for fluorescence-guided surgery of pancreatic cancer	44
Functional genomic approaches in acute myeloid leukemia: Insights into disease models and the therapeutic potential of reprogramming	44
Corrigendum to “P-REX1 amplification promotes progression of cutaneous melanomavia the PAK1/P38/MMP-2 pathway” [Cancer Lett. 407 (2017) 66–75]	44
Acute myocardial infarction following allogeneic hematopoietic stem cell transplantation: A national cohort study	44
The role of the microbiota in cancer drug resistance and emerging therapeutic strategies	44
Interplay among extracellular vesicles, cancer stemness and immune regulation in driving hepatocellular carcinoma progression	43
Copper in hepatocellular carcinoma： A double-edged sword with therapeutic potentials	43
Radiotherapy-induced tumor physical microenvironment remodeling to overcome immunotherapy resistance	43
Low-dose metronomic chemotherapy triggers oxidized mtDNA sensing inside tumor cells to potentiate CD8+T anti-tumor immunity	43
Shifts in cancer funding: An overview of terminated research grants at the national cancer institute	43
The feedback loop of AURKA/DDX5/TMEM147-AS1/let-7 drives lipophagy to induce cisplatin resistance in epithelial ovarian cancer	43
Single-cell chemokine receptor profiles delineate the immune contexture of tertiary lymphoid structures in head and neck squamous cell carcinoma	43
The post-chemotherapy changes of tumor physical microenvironment: Targeting extracellular matrix to address chemoresistance	43
Active immunization with a structurally aggregated PD-L1 antigen breaks T and B immune tolerance in non-human primates and exhibits in vivo anti-tumoral effects in immunocompetent mouse tumor models	42
Single-cell RNA-sequencing of human spleens reveals an IDO-1+ tolerogenic dendritic cell subset in pancreatic cancer patients that is absent in normal individuals	42
Antimetastatic activity of B7-H3-targeted CAR T-cell therapy in triple-negative breast cancer	42
Suppressive immune microenvironment and CART therapy for glioblastoma: Future prospects and challenges	42
The safety and efficacy outcomes of Minnelide given alone or in combination with paclitaxel in advanced gastric cancer: A phase I trial	42
Protective role of epithelial deoxyhypusine synthase in colorectal carcinogenesis caused by deletion of the adenomatous polyposis coli gene	42
Local delivery of optimized nanobodies targeting the PD-1/PD-L1 axis with a self-amplifying RNA viral vector induces potent antitumor responses	41
Unraveling pancreatic ductal adenocarcinoma at single-cell resolution with spatial insights: From mechanisms to clinical translation	41
Exercise in cancer prevention and anticancer therapy: Efficacy, molecular mechanisms and clinical information	41
Immunotherapy for extensive-stage small cell lung cancer: current status, challenges and future strategies	41
GPRC5A promotes gallbladder cancer metastasis by upregulating TNS4 via the JAK2–STAT3 pathway	41

Dysregulation of autophagy in gastric carcinoma: Pathways to tumor progression and resistance to therapy	41
hnRNPLL regulates MYOF alternative splicing and correlates with early metastasis in pancreatic ductal adenocarcinoma	40
Application prospect of circular RNA-based neoantigen vaccine in tumor immunotherapy	40
Frontiers in pancreatic cancer on biomarkers, microenvironment, and immunotherapy	40
SENP1-Sirt3 axis promotes cholesterol biosynthesis in tumor-associated macrophages to suppress anti-tumor immunity	40
Phase separation of EEF1E1 promotes tumor stemness via PTEN/AKT-mediated DNA repair in hepatocellular carcinoma	40
RNA binding protein RALY activates the cholesterol synthesis pathway through an MTA1 splicing switch in hepatocellular carcinoma	40
Comprehensive clinico-genomic analysis of pancreatic ductal adenocarcinoma: Overcoming biases and limitations	40
Smoking-induced CCNA2 expression promotes lung adenocarcinoma tumorigenesis by boosting AT2/AT2-like cell differentiation	40
The CGCG response assessment criteria for spinal cord gliomas	40
Tumor-nerve interactions in cancer regulation and progression	40
Pan-cancer atlas of tumor-resident microbiome, immunity and prognosis	40
Mitochondrial fragmentation in liver cancer: Emerging player and promising therapeutic opportunities	40
Treatment strategies and molecular mechanism of radiotherapy combined with immunotherapy in colorectal cancer	40
AI-based radiomic features predict outcomes and the added benefit of chemoimmunotherapy over chemotherapy in extensive stage small cell lung cancer: A multi-institutional study	39
LINC00978 regulates metabolic rewiring to promote the malignancy of glioblastoma through AKR1B1	39
A journey to excellence: Disseminating groundbreaking discoveries in oncology research	39
Targeting ephrin receptor A10 with antibody-drug conjugates for breast cancer	39
Super-giant cells: Toward understanding tumor origins on the organismal level	39
A phase Ib/II trial of XL888 (HSP90 inhibitor) and pembrolizumab in metastatic pancreatic cancer with translational immune profiling	39
Single-nucleus sequencing unveils heterogeneity in renal cell carcinomas microenvironment: Insights into pathogenic origins and treatment-responsive cellular subgroups	39
WITHDRAWN: Proteomic analysis of plasma-derived exosomes identifies biomarkers that distinguish brain and liver metastasis in lung cancer patients	39
EDARADD promotes colon cancer progression by suppressing E3 ligase Trim21-mediated ubiquitination and degradation of Snail	38
Corrigendum to “NSUN4 mediated RNA 5-methylcytosine promotes the malignant progression of glioma through improving the CDC42 mRNA stabilization” [Cancer Lett. (2024) 597 217059]	38
Effective leukemia-to-granulocyte induction by a cocktail of RUNX1, SPI1 and CEBPE	38
Corrigendum to “Scattered DUSP28 is a novel biomarker responsible for aggravating malignancy via the autocrine and paracrine signaling in metastatic pancreatic cancer” [Cancer Lett. 456 (2019 Aug 1) 1	38
Circadian disruption in cancer and regulation of cancer stem cells by circadian clock genes: An updated review	38
Corrigendum to “Helicobacter pylori upregulates Nanog and Oct4 via Wnt/β-catenin signaling pathway to promote cancer stem cell-like properties in human gastric cancer” [Canc. Lett. 374 (2016) 292–303]	38
Corrigendum to “The vulnerabilities of chemotherapy resistant pancreatic cancer revealed by organoids of pre- and post- neoadjuvant therapy” [Cancer Lett. (2026), Online ahead of print]	37
The eIF3a translational control axis in the Wnt/β-catenin signaling pathway and colon tumorigenesis	37
Revisiting the advances and challenges in the clinical applications of extracellular vesicles in cancer	37
A novel GRK3-HDAC2 regulatory pathway is a key direct link between neuroendocrine differentiation and angiogenesis in prostate cancer progression	37
SIK1 promotes ferroptosis resistance in pancreatic cancer via HDAC5-STAT6-SLC7A11 axis	37
CRISPR/Cas9 screen reveals that targeting TRIM34 enhances ferroptosis sensitivity and augments immunotherapy efficacy in hepatocellular carcinoma	37
Disparities in mortality risk after diagnosis of hematological malignancies in 185 countries: A global data analysis	37
Deciphering the tumor-suppressive role of PSMB9 in melanoma through multi-omics and single-cell transcriptome analyses	37
Dual targeting PPARα and NPC1L1 metabolic vulnerabilities blocks tumorigenesis	37
The mitotic regulator RCC2 promotes glucose metabolism through BACH1-dependent transcriptional upregulation of hexokinase II in glioma	37
Targeted inhibition of CHKα and mTOR in models of pancreatic ductal adenocarcinoma: A novel regimen for metastasis	36
Neutrophils exposed to a cholesterol metabolite secrete extracellular vesicles that promote epithelial-mesenchymal transition and stemness in breast cancer cells	36
Identification of SMARCAL1 as a molecular target for small cell lung cancer treatment	36
Lipid metabolism reprogramming of CD8+ T cell and therapeutic implications in cancer	36
High-content drug screening in zebrafish xenografts reveals high efficacy of dual MCL-1/BCL-XL inhibition against Ewing sarcoma	36
Deglycosylated PD-L1 is a biomarker for immune checkpoint blockade response: a real-world study in breast cancer patients in Taiwan	36
Identification of SPP1+ macrophages in promoting cancer stemness via vitronectin and CCL15 signals crosstalk in liver cancer	36
PI3K PROTAC overcomes the lapatinib resistance in PIK3CA-mutant HER2 positive breast cancer	36
Unlocking c-MET: A comprehensive journey into targeted therapies for breast cancer	36
Enhanced prediction of breast cancer patient response to chemotherapy by integrating deconvolved expression patterns of immune, stromal and tumor cells	36
RNA methyltransferase METTL16: From molecular mechanisms to therapeutic prospects in cancers	36
Biodistribution and therapeutic efficacy of a gold nanoparticle-based targeted drug delivery system against pancreatic cancer	35
Keloids revisited: Current concepts in treatment and differential diagnosis	35
Corrigendum to “Anti-tumor activity of antibody drug conjugate targeting aspartate-β-hydroxylase in pancreatic ductal adenocarcinoma” [Cancer Lett. 449 (2019) 87–98]	35
Editorial Board	35
Targeting tumor-intrinsic SLC16A3 to enhance anti-PD-1 efficacy via tumor immune microenvironment reprogramming	35
Histone lactylation dynamics: Unlocking the triad of metabolism, epigenetics, and immune regulation in metastatic cascade of pancreatic cancer	35
ITPR1-AS1 promotes small cell lung cancer metastasis by facilitating P21 splicing and stabilizing DDX3X to activate the cRaf-MEK-ERK cascade	35
Corrigendum to “Pharmacological inhibition of DUSP6 suppresses gastric cancer growth and metastasis and overcomes cisplatin resistance” [Cancer Lett. (2018) 412 243–255]	35
CPSF3 regulates alternative polyadenylation of CNIH2 to promote esophageal squamous cell carcinoma progression	35
Single-cell transcriptomics reveals intratumor heterogeneity and the potential roles of cancer stem cells and myCAFs in colorectal cancer liver metastasis and recurrence	35
The intersections between neuroscience and medulloblastoma	35
Editorial Board	34
Dual blockade of PD-1 and CTLA-4 generates long-lasting immunity against irradiated glioblastoma	34
PPDPF promotes esophageal squamous cell carcinoma progression by blocking PCCA binding to PCCB and inhibiting methionine catabolism	34
Tumor-derived extracellular vesicles induce invalid cytokine release and exhaustion of CD19 CAR-T Cells	34
Evolution and contemporary role of metronomic chemotherapy in the treatment of neuroblastoma	34
Significance of longitudinal Epstein–Barr virus DNA combined with multipoint tumor response for dynamic risk stratification and treatment adaptation in nasopharyngeal carcinoma	34
Editorial Board	34
Loss of ASAP1 in the MMTV-PyMT model of luminal breast cancer activates AKT, accelerates tumorigenesis, and promotes metastasis	34
Editorial Board	34
Radiosensitization of intrahepatic cholangiocarcinoma and metastatic disease in the liver using microbubble cavitation: results from a phase 2 clinical trial	34
A two-stage genome-wide association study to identify novel genetic loci associated with irAEs in lung cancer patients receiving PD-1/PD-L1 inhibitors	34
Confusion about the article: Natural product triptolide induces GSDME-mediated pyroptosis in head and neck cancer through suppressing mitochondrial hexokinase-ΙΙ	34
Editorial Board	34
IgSF protein EWI2 is a tumor suppressor	34
Editorial Board	34
Cell adhesion molecule ITGB2 promotes CAR-T cell therapy in B-cell malignancies	34
The new era of pancreatic cancer treatment: Application of nanotechnology breaking through bottlenecks	34
A novel role of TGFBI in macrophage polarization and macrophage-induced pancreatic cancer growth and therapeutic resistance	33
TFAP2C-DDR1 axis regulates resistance to CDK4/6 inhibitor in breast cancer	33
Harnessing genetic interactions for prediction of immune checkpoint inhibitors response signature in cancer cells	33
Loss of branched-chain amino acid (BCAA) metabolism mediated by IGF2BP1-LPAL2-YBX1 interaction promotes malignancy in gallbladder cancer	33
HMGB1 in the interplay between autophagy and apoptosis in cancer	33
Microbiome and gartynecologic cancer	33
Targeting the molecular chaperone CCT2 inhibits GBM progression by influencing KRAS stability	33
CHEK2 deficiency increase the response to PD-1 inhibitors by affecting the tumor immune microenvironment	33
Multi-functional extracellular vesicles: Potentials in cancer immunotherapy	33
A novel microenvironment regulated system CAR-T (MRS.CAR-T) for immunotherapeutic treatment of esophageal squamous carcinoma	33
AXL signal mediates adaptive resistance to KRAS G12C inhibitors in KRAS G12C-mutant tumor cells	33
MFN2-CD36 interaction regulates mitochondrial lipid digestion in cancer-associated fibroblasts and promotes esophageal squamous cell carcinoma progression	33
Drug screening reveals differential drug response in primary and metastatic clear cell sarcoma	33
Metformin inhibits neutrophil extracellular traps-promoted pancreatic carcinogenesis in obese mice	33
Deciphering the immune modulation through deep transcriptomic profiling and therapeutic implications of DNA damage repair pattern in hepatocellular carcinoma	32
Cancer stem cells and tumor-associated macrophages: Interactions and therapeutic opportunities	32
Exosomal cannabidiol: A promising candidate for targeted oral delivery against breast cancer	32
Magnolin targeting of the JNK/Sp1/MMP15 signaling axis suppresses cervical cancer microenvironment and metastasis via microbiota modulation	32