Biochimica et Biophysica Acta-General Subjects

Article	Citations
Congenital disorders of glycosylation: Still “hot” in 2020	80
Galactose in human metabolism, glycosylation and congenital metabolic diseases: Time for a closer look	62
The need for novel cryoprotectants and cryopreservation protocols: Insights into the importance of biophysical investigation and cell permeability	61
Mechanisms of productive folding and endoplasmic reticulum-associated degradation of glycoproteins and non-glycoproteins	49
Genetic modification to design a stable yeast-expressed recombinant SARS-CoV-2 receptor binding domain as a COVID-19 vaccine candidate	47
Resistance mechanisms to targeted therapy in BRAF-mutant melanoma - A mini review	43
Tailoring of the rheological properties of bioinks to improve bioprinting and bioassembly for tissue replacement	43
The antimicrobial peptide Temporin L impairs E. coli cell division by interacting with FtsZ and the divisome complex	38
The structure – Activity correlation in the family of dicationic imidazolium surfactants: Antimicrobial properties and cytotoxic effect	36
Trending topics of SIRT1 in tumorigenicity	36
Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold	34
The new role of poly (rC)-binding proteins as iron transport chaperones: Proteins that could couple with inter-organelle interactions to safely traffic iron	34
Golgi inCOGnito: From vesicle tethering to human disease	33
GDF15 as a central mediator for integrated stress response and a promising therapeutic molecule for metabolic disorders and NASH	32
Copper and lipid metabolism: A reciprocal relationship	29
Role of PARP-1 in mitochondrial homeostasis	29
Receptor-based targeting of engineered nanocarrier against solid tumors: Recent progress and challenges ahead	29
Recent developments in membrane curvature sensing and induction by proteins	29
Hyaluronic acid engrafted metformin loaded graphene oxide nanoparticle as CD44 targeted anti-cancer therapy for triple negative breast cancer	27
Active probing of the mechanical properties of biological and synthetic vesicles	26
Combinatorial therapy of Thymoquinone and Emodin synergistically enhances apoptosis, attenuates cell migration and reduces stemness efficiently in breast cancer	26
The multiple activities of BAG3 protein: Mechanisms	25
Structure of the dihydrolipoamide succinyltransferase (E2) component of the human alpha-ketoglutarate dehydrogenase complex (hKGDHc) revealed by cryo-EM and cross-linking mass spectrometry: Implicatio	24
Release of extracellular vesicle miR-494-3p by ARPE-19 cells with impaired mitochondria	24
Advancement in design of nanostructured lipid carriers for cancer targeting and theranostic application	24

Biometals and glycosylation in humans: Congenital disorders of glycosylation shed lights into the crucial role of Golgi manganese homeostasis	23
The evolving genetic landscape of congenital disorders of glycosylation	23
Matrix vesicle biomimetics harboring Annexin A5 and alkaline phosphatase bind to the native collagen matrix produced by mineralizing vascular smooth muscle cells	23
Human proline specific peptidases: A comprehensive analysis	22
Expression of elastolytic cathepsins in human skin and their involvement in age-dependent elastin degradation	22
The c-MET oncoprotein: Function, mechanisms of degradation and its targeting by novel anti-cancer agents	21
High-affinity binding and catalytic activity of His/Tyr-based sequences: Extending heme-regulatory motifs beyond CP	21
Composite 5-methylations of cytosines modulate i-motif stability in a sequence-specific manner: Implications for DNA nanotechnology and epigenetic regulation of plant telomeric DNA	21
Roles of protein arginine methyltransferase 1 (PRMT1) in brain development and disease	20
The synthetic varespladib molecule is a multi-functional inhibitor for PLA2 and PLA2-like ophidic toxins	20
Mitochondria as targets for toxicity and metabolism research using zebrafish	20
Can food and food supplements be deployed in the fight against the COVID 19 pandemic?	20
Functional characterization of the ATPase-like activity displayed by a catalytic amyloid	19
Machine learning and ligand binding predictions: A review of data, methods, and obstacles	19
Irisin regulates thermogenesis and lipolysis in 3T3-L1 adipocytes	19
Evolution of milk oligosaccharides: Origin and selectivity of the ratio of milk oligosaccharides to lactose among mammals	19
New and potential strategies for the treatment of PMM2-CDG	19
Mitophagy in plants	19
Molecular determinant for specificity: Differential interaction of α-amylases with their proteinaceous inhibitors	18
Imaging extracelluar vesicles by transmission electron microscopy: Coping with technical hurdles and morphological interpretation	18
3,3′-Diselenodipropionic acid (DSePA): A redox active multifunctional molecule of biological relevance	18
Hyaluronan degradation and release of a hyaluronan-aggrecan complex from perineuronal nets in the aged mouse brain	18
Characterizing liver sinusoidal endothelial cell fenestrae on soft substrates upon AFM imaging and deep learning	18
Microscopy approaches to study extracellular vesicles	18
Therapeutic targeting of PIM KINASE signaling in cancer therapy: Structural and clinical prospects	17
Human galectin-16 has a pseudo ligand binding site and plays a role in regulating c-Rel-mediated lymphocyte activity	17
The relation between lignin sequence and its 3D structure	17
Radioiodination of extravesicular surface constituents to study the biocorona, cell trafficking and storage stability of extracellular vesicles	17
Modelling Förster resonance energy transfer (FRET) using anisotropy resolved multi-dimensional emission spectroscopy (ARMES)	16
α1,6-Fucosyltransferase contributes to cell migration and proliferation as well as to cancer stemness features in pancreatic carcinoma	16
Humanin-induced autophagy plays important roles in skeletal muscle function and lifespan extension	16
CCR5 tyrosine sulfation heterogeneity generates cell surface receptor subpopulations with different ligand binding properties	16
Iron mineralization and core dissociation in mammalian homopolymeric H-ferritin: Current understanding and future perspectives	15
Aggregation of Lipid A Variants: A Hybrid Particle-Field Model	15
Frontal affinity chromatography: An excellent method of analyzing weak biomolecular interactions based on a unique principle	15
CDG biochemical screening: Where do we stand?	15
Synchrotron FTIR microspectroscopy revealed apoptosis-induced biomolecular changes of cholangiocarcinoma cells treated with ursolic acid	15
Andrographolide upregulates protein quality control mechanisms in cell and mouse through upregulation of mTORC1 function	15
PSMD11, PTPRM and PTPRB as novel biomarkers of pancreatic cancer progression	15
Cross-reactivity of two human IL-6 family cytokines OSM and LIF explored by protein-protein docking and molecular dynamics simulation	15
A post-insertion strategy for surface functionalization of bacterial and mammalian cell-derived extracellular vesicles	15
Lipid membranes exposed to dispersions of phytantriol and monoolein cubosomes: Langmuir monolayer and HeLa cell membrane studies	15
Metabolic characterization of a paused-like pluripotent state	14
Immobilization of β-galactosidase by halloysite-adsorption and entrapment in a cellulose nanocrystals matrix	14
Transcription factor NF-κB unravels nucleosomes	14
Molecular imaging for mitochondrial metabolism and oxidative stress in mitochondrial diseases and neurodegenerative disorders	14
Tumor hypoxia regulates ganglioside GM3 synthase, which contributes to oxidative stress resistance in malignant melanoma	14
Mitochondrial fission factor (Mff) is required for organization of the mitochondrial sheath in spermatids	14
Retrospective ensemble docking of allosteric modulators in an adenosine G-protein-coupled receptor	14
Mitochondrial-derived peptides and exercise	14

The role of active-site amino acid residues in the cleavage of DNA and RNA substrates by human apurinic/apyrimidinic endonuclease APE1	14
NDRG1 suppresses basal and hypoxia-induced autophagy at both the initiation and degradation stages and sensitizes pancreatic cancer cells to lysosomal membrane permeabilization	14
O-GlcNAc modification regulates MTA1 transcriptional activity during breast cancer cell genotoxic adaptation	14
S-glutathionylation of human glyceraldehyde-3-phosphate dehydrogenase and possible role of Cys152-Cys156 disulfide bridge in the active site of the protein	13
Regulation of N-glycosylation and secretion of Isthmin-1 by its C-mannosylation	13
A mechanistic review of Parkin activation	13
TAT-tagging of VIP exerts positive allosteric modulation of the PAC1 receptor and enhances VIP neuroprotective effect in the MPTP mouse model of Parkinson's disease	13
EcDBS1R6: A novel cationic antimicrobial peptide derived from a signal peptide sequence	12
Antitumoral synergism between a copper(II) complex and cisplatin improves in vitro and in vivo anticancer activity against melanoma, lung and breast cancer cells	12
AMPK is essential for IL-10 expression and for maintaining balance between inflammatory and cytoprotective signaling	12
A pericellular hyaluronan matrix is required for the morphological maturation of cortical neurons.	12
The effect of UV radiation in the presence of TiO2-NPs on Leishmania major promastigotes	12
Characterization of three bacterial glycoside hydrolase family 9 endoglucanases with different modular architectures isolated from a compost metagenome	12
Enzymatic versatility and thermostability of a new aryl-alcohol oxidase from Thermothelomyces thermophilus M77	12
Humanin and Alzheimer's disease: The beginning of a new field	12
Roles of humanin and derivatives on the pathology of neurodegenerative diseases and cognition	12
Surface-modified magnetite nanoparticles affect lysozyme amyloid fibrillization	12
The fibrinogen C-terminal domain is seldom C-mannosylated but its C-mannosylation is important for the secretion of microfibril-associated glycoprotein 4	12
Current insights on extracellular vesicle-mediated glioblastoma progression: Implications in drug resistance and epithelial-mesenchymal transition	12
Metformin-ROS-Nrf2 connection in the host defense mechanism against oxidative stress, apoptosis, cancers, and ageing	12
What's new about CNBP? Divergent functions and activities for a conserved nucleic acid binding protein	11
Sense the moment: A highly sensitive antimicrobial activity predictor based on hydrophobic moment	11
Human importin α3 and its N-terminal truncated form, without the importin-β-binding domain, are oligomeric species with a low conformational stability in solution	11
Doxorubicin exhibits strong and selective association with VEGF Pu22 G-quadruplex	11
The sequence [EKRKI(E/R)(K/L/R/S/T)] is a nuclear localization signal for importin 7 binding (NLS7)	11
Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP)	11
The action of Echis carinatus and Naja naja venoms on human neutrophils; an emphasis on NETosis	11
Metabolic engineering of non-pathogenic Escherichia coli strains for the controlled production of low molecular weight heparosan and size-specific heparosan oligosaccharides	11
Regulatory mechanisms of mitophagy in yeast	11
Differential interactions of the antimicrobial peptide, RQ18, with phospholipids and cholesterol modulate its selectivity for microorganism membranes	11
Plasma mitochondrial derived peptides MOTS-c and SHLP2 positively associate with android and liver fat in people without diabetes	11
Cooperative effects on the compaction of DNA fragments by the nucleoid protein H-NS and the crowding agent PEG probed by Magnetic Tweezers	11
Nanoscale infrared probing of amyloid formation within the pleomorphic adenoma tissue	11
G-quadruplex DNA structures and their relevance in radioprotection	11
Soybean lectin induces autophagy through P2RX7 dependent activation of NF-κB-ROS pathway to kill intracellular mycobacteria	11
Nanobodies as powerful pulmonary targeted biotherapeutics against SARS-CoV-2, pharmaceutical point of view	11
Development and characterisation of a peptidergic N-and C-terminally stabilised mammalian NPY1R agonist which protects against diabetes induction	10
The thiosemicarbazone, DpC, broadly synergizes with multiple anti-cancer therapeutics and demonstrates temperature- and energy-dependent uptake by tumor cells	10
Megalin-mediated albumin endocytosis in renal proximal tubules is involved in the antiproteinuric effect of angiotensin II type 1 receptor blocker in a subclinical acute kidney injury animal model	10
Nanomechanical characterization of exosomes and concomitant nanoparticles from blood plasma by PeakForce AFM in liquid	10
Involvement of the α-helical and Src homology 3 domains in the molecular assembly and enzymatic activity of human α1,6-fucosyltransferase, FUT8	10
Inhibiting protein aggregation with nanomaterials: The underlying mechanisms and impact factors	10
Development and characterisation of novel, enzymatically stable oxytocin analogues with beneficial antidiabetic effects in high fat fed mice	10
Efficient photodynamic inactivation of Leishmania parasites mediated by lipophilic water-soluble Zn(II) porphyrin ZnTnHex-2-PyP4+	10
SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses	10
Hybrid giant lipid vesicles incorporating a PMMA-based copolymer	10
Origin of heat capacity increment in DNA folding: The hydration effect	10
Piperlonguminine a new mitochondrial aldehyde dehydrogenase activator protects the heart from ischemia/reperfusion injury	10
BamA is required for autotransporter secretion	10
Pro-angiogenic approach for skeletal muscle regeneration	10
A multi-approach analysis highlights the relevance of RPA-1 as a telomere end-binding protein (TEBP) in Leishmania amazonensis	10
Recognition of glycan and protein substrates by N-acetylglucosaminyltransferase-V	10
Modulation of tau protein aggregation using ‘Trojan’ sequences	10
Eugenol disrupts Plasmodium falciparum intracellular development during the erythrocytic cycle and protects against cerebral malaria	10
Sequence specific hydrogen bond of DNA with denaturants affects its stability: Spectroscopic and simulation studies	10
The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway	10
Role of platelet-derived growth factor c on endothelial dysfunction in cardiovascular diseases	10
Inhibiting BTB domain and CNC homolog 1 (Bach1) as an alternative to increase Nrf2 activation in chronic diseases	10
Glucose regulation of the paralogous glucose sensing receptors Rgt2 and Snf3 of the yeast Saccharomyces cerevisiae	10
Regulatory expression of bone morphogenetic protein 6 by 2,2′-dipyridyl	10
Dysregulation of hexosamine biosynthetic pathway wiring metabolic signaling circuits in cancer	9
Kinetic modeling of glucose central metabolism in hepatocytes and hepatoma cells	9
The effect of DS16570511, a new inhibitor of mitochondrial calcium uniporter, on calcium homeostasis, metabolism, and functional state of cultured cortical neurons and isolated brain mitochondria	9
Degradation of paternal mitochondria via mitophagy	9
Urinary metabolite prognostic biomarker panel for pancreatic ductal adenocarcinomas	9
The mitochondrial aspartate/glutamate carrier (AGC or Aralar1) isoforms in D. melanogaster: biochemical characterization, gene structure, and evolutionary analysis	9
Hidden phenotypes of PINK1/Parkin knockout mice	9
Circulating humanin is lower in coronary artery disease and is a prognostic biomarker for major cardiac events in humans	9
Deficiency in Beclin1 attenuates alcohol-induced cardiac dysfunction via inhibition of ferroptosis	9
BMP6 binding to heparin and heparan sulfate is mediated by N-terminal and C-terminal clustered basic residues	8
The role of cellular iron deficiency in controlling iron export	8
An atomic perspective on improving daptomycin's activity	8
Coating of magnetic nanoparticles affects their interactions with model cell membranes	8
Proteomic identification of tumor- and metastasis-associated galectin-1 in claudin-low breast cancer	8
S-allyl cysteine: A potential compound against skeletal muscle atrophy	8
Cadmium elicits alterations in mitochondrial morphology and functionality in C3H10T1/2Cl8 mouse embryonic fibroblasts	8
Shear stress induced lipid order and permeability changes of giant unilamellar vesicles	8
Human TRPV6-pathies caused by gene mutations	8
Promoter G-quadruplex favours epigenetic reprogramming-induced atypical expression of ZEB1 in cancer cells	8
Expression of GALNT8 and O-glycosylation of BMP receptor 1A suppress breast cancer cell proliferation by upregulating ERα levels	8

Products of S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase: Relation between S-nitrosylation and oxidation	8
Role of thyroid hormones-induced oxidative stress on cardiovascular physiology	8
Interactions between PAMAM dendrimers and DOPC lipid multilayers: Membrane thinning and structural disorder	8
Computation of FRAP recovery times for linker histone – chromatin binding on the basis of Brownian dynamics simulations	8
Non-contact microfluidic mechanical property measurements of single apoptotic bodies	8
Effect of the ammonium salt anion on the structure of doxorubicin complex and PEGylated liposomal doxorubicin nanodrugs	8
Iron overload, oxidative stress and vascular dysfunction: Evidences from clinical studies and animal models	8
Oxidative stress-mediated epidermal growth factor receptor activation regulates PM2.5-induced over-secretion of pro-inflammatory mediators from human bronchial epithelial cells	8
Polyamines and its analogue modulates amyloid fibrillation in lysozyme: A comparative investigation	7
Dynamic cross correlation analysis of Thermus thermophilus alkaline phosphatase and determinants of thermostability	7
Requirement for C-mannosylation to be secreted and activated a disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4)	7
Cancer metabolism within tumor microenvironments	7
The cytosolic isoform of glutaredoxin 2 promotes cell migration and invasion	7
How neutron scattering techniques benefit investigating structures and dynamics of monoclonal antibody	7
Ecotin and LamB in Escherichia coli influence the susceptibility to Type VI secretion-mediated interbacterial competition and killing by Vibrio cholerae	7
Characterization of two siderophores produced by Bacillus megaterium: A preliminary investigation into their potential as therapeutic agents	7
Curcumin rescue p53Y220C in BxPC-3 pancreatic adenocarcinomas cell line: Evidence-based on computational, biophysical, and in vivo studies	7
Glycan dependent refolding activity of ER glucosyltransferase (UGGT)	7
Intermolecular insights into allosteric inhibition of histone lysine-specific demethylase 1	7
Yeast mitophagy: Unanswered questions	7
Transport mechanism of hydroxy-propyl-beta-cyclodextrin modified solid lipid nanoparticles across human epithelial cells for the oral absorption of antileishmanial drugs	7
Mitochondrial reactive zones in antiviral innate immunity	7
Acetylation and phosphorylation processes modulate Tau’s binding to microtubules: A molecular dynamics study	7
Ascorbate-and iron-driven redox activity of Dp44mT and Emodin facilitates peroxidation of micelles and bicelles	7
Engineering tumor stromal mechanics for improved T cell therapy	7
Human cancer xenografts in immunocompromised mice provide an advanced genuine tumor model for research and drug development-A revisit of murine models for human cancers	7
SOD1 mutations cause hypersensitivity to high-pressure-induced oxidative stress in Saccharomyces cerevisiae	7