Clinical and Experimental Pharmacology and Physiology

Article	Citations
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Efficacy and safety of baricitinib for the treatment of moderate‐to‐severe atopic dermatitis: A systematic review and meta‐analysis of randomized clinical trials	43
Ablation of TRPC3 compromises bicarbonate and phosphate transporter activity in mice proximal tubular cells	41
Rabeprazole destroyed gastric epithelial barrier function through FOXF1/STAT3‐mediated ZO‐1 expression	35
Reliability of Matrix‐Assisted Laser Desorption‐Ionisation Time‐of‐Flight Mass Spectrometry as a Method for Drug‐Resistant Tuberculosis Gene Identification	33
Glycyrrhizic Acid Ameliorates LPS‐Induced WI‐38 Cell Inflammation, Oxidative Stress, and Ferroptosis via Targeting METTL14 in Infantile Pneumonia	28
Fibroblast growth factor 10 ameliorates renal ischaemia–reperfusion injury by attenuating mitochondrial damage	25
LncRNA PRKCQ‐AS1 regulates paclitaxel resistance in triple‐negative breast cancer cells through miR‐361‐5p/PIK3C3 mediated autophagy	24
Ulinastatin affects focal cerebral ischemia–reperfusion injury via SOCS1‐mediated JAK2/STAT3 signalling pathway	22
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Weight‐based oxytocin infusion for preventing uterine atony during caesarean delivery in non‐labouring patients: A dose–response study	20
Development and Validation of a Comprehensive Risk Prediction Model for Polypoid Lesions of the Gallbladder	19
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ALKBH5 inhibits the SIRT3/ACC1 axis to regulate fatty acid metabolism via an m6A‐IGF2BP1‐dependent manner in cervical squamous cell carcinoma	17
Corticosterone‐Induced Myocardial Dysfunctions and the Cardioprotective Role of Tauroursodeoxycholic Acid: An Experimental Study in Mice	17
SIRT1 targeted by miR‐211‐5p regulated proliferation and apoptosis of Dex‐treated growth plate chondrocytes via mediating SOX2	16
Effects of a single dose of rocuronium in patients with different body fat percentages: A randomised controlled trial	16
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Indole‐3‐Propionic Acid Improves Vascular Function in High‐Fat Diet‐Induced Obese Mice via eNOS	14
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Correction to “low‐intensity pulsed ultrasound prevents prolonged hypoxia‐induced cardiac fibrosis through HIF ‐1α/ DNMT3a	14
Ginsenoside Rh4 inhibits the malignant progression of multiple myeloma and induces ferroptosis by regulating SIRT2	14
Sympathetic Nerve Activation Drives Cardiac Fibrosis and Arrhythmia in Lean Metabolic Dysfunction‐Associated Steatohepatitis Mice Concurrently Exposed to Ethanol and a High‐Fat/High‐Cholesterol Diet	14

Pyroptosis‐Mediated Antitumor Activity of Cinobufagin in Non‐Small Cell Lung Cancer	13
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EZH2 promotes the progression of osteosarcoma through the activation of the AKT/GSK3β pathway	12
Adrenalectomy attenuates hyperalgesia but does not regulate muscle wasting in a female rat model of fibromyalgia	12
BRAP Homologue Deficiency Exacerbates Airway Inflammation in Mouse Models of Experimental Asthma‐Like Disease	12
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AEBP1 restores osteoblastic differentiation under dexamethasone treatment by activating PI3K/AKT signalling	11
Bufalin reduces myocardial infarction‐induced myocardial fibrosis and improves cardiac function by inhibiting the NLRP3/IL‐1β signalling pathway	11
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Protective effect of melatonin and ascorbic acid combination on sepsis‐induced lung injury: An Experimental study	11
Thioredoxin‐1 regulates the autophagy induced by oxidative stress through LC3‐II in human lens epithelial cells	10
TLR4 Inhibitor TAK‐242 Protected Henoch–Schonlein Purpura Nephritis in Rats by Regulating Inflammatory Response and Immune Competence via NF‐ κB/NLRP3<	10
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Artesunate alleviates psoriasis‐like dermatitis by reducing interleukin‐23 expression in tumor necrosis factor‐alpha‐induced HaCaT cells	10
Sex Steroid Control of Serotonergic System: Clinical Implications for Psychiatric Disorders and Addiction Treatment	10
GSK3β inhibitor TDZD8 ameliorates brain damage through both ROS scavenging and inhibition of apoptosis in hyperglycaemic subarachnoid haemorrhage rats	10
Erythropoietin hyporesponsiveness in non‐alcoholic fatty liver disease	10
Rapid detection of guttae area using aniline blue staining in Fuchs endothelial corneal dystrophy mouse model	9
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BCR::ABL1‐positive chronic myeloid leukaemia with CALR mutation	9
RETRACTION : Diosmetin Exerts Cardioprotective Effect on Myocardial Ischaemia Injury in Neonatal Rats by Decreasing Oxidative Stress and Myocardial Apoptosis	9
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Therapeutic potential of curcumin in ARDS and COVID‐19	9
A spontaneous hyperglycaemic cynomolgus monkey presents cognitive deficits, neurological dysfunction and cataract	9
Sevoflurane‐induced P300 promotes neuron apoptosis via Sp1/CDK9 pathway	9
Phosphatidylserine accelerates wound healing and reduces necrosis in the rats: Growth factor activation	9
Esculentoside A ameliorates DNCB‐induced atopic dermatitis by suppressing the ROS‐NLRP3 axis via activating the Nrf2 pathway	8
Nicorandil mitigates amiodarone‐induced pulmonary toxicity and fibrosis in association with the inhibition of lung TGF‐β1/PI3K/Akt1‐p/mTOR axis in rats	8
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Agomelatine alleviates steroid‐induced osteoporosis by targeting SIRT1/RANKL/FOXO1/OPG signalling in rats	8
Prognostic value of inflammatory and nutritional indexes among advanced NSCLC patients receiving PD‐1 inhibitor therapy	8
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Sirt6, Deubiquitinated and Stabilised by USP9X, Takes Essential Actions on the Pathogenesis of Experimental Autoimmune Myasthenia Gravis by Regulating CD4+ T Cells	8
Metabolomic modelling and neuroprotective effects of carvacrol against acrylamide toxicity in rat's brain and sciatic nerve	8
Electroacupuncture Attenuates Cerebral Ischemia–Reperfusion Injury by Inhibiting Ferroptosis via the p53/SLC7A11 Pathway	8
Isoferulic Acid Inhibits Proliferation and Migration of Pancreatic Cancer Cells, and Promotes the Apoptosis of Pancreatic Cancer Cells in a Mitochondria‐Dependent Manner Through Inhibiting NF	8
In vitro effects and mathematical modelling of CTCE‐9908 (a chemokine receptor 4 antagonist) on melanoma cell survival	8
Hsa_circ_0001204 modulates inflammatory response of macrophages infected by Mycobacterium tuberculosis via TLR4/NF‐κB signalling pathway	8
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Kaempferol Ameliorates Sepsis‐Acute Lung Injury by Promoting Succinylation of SRPK1	7
Hsa_circ_0097922 promotes tamoxifen resistance and cell malignant behaviour of breast cancer cells by regulating ACTN4 expression via miR‐876‐3p	7
Kruppel‐Like Factor 5 Modulates the Nuclear Factor Erythroid‐2‐Related Factor 2/Heme Oxygenase 1 Signalling Pathway to Regulate Vascular Smooth Muscle Cell Ferroptosis in Abdominal Aortic Aneurysm	7
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A 2‐week treatment with 5‐azacytidine improved the hypercontractility state in prostate from obese mice: Role of the nitric oxide‐cyclic guanosine monophosphate signalling pathway	7
Global, Regional, and National Temporal Trend and Patterns of Change in the Burden of Asthma From 1990 to 2021: An Analysis of the Global Burden of Disease Study 2021	7
Relationship between serum CHIP levels with cardiovascular disease in maintenance haemodialysis patients	7
Overexpression of miR‐718 in Keratinocytes Affects the Psoriatic Inflammation via Targeting STAT1: In Vitro and In Vivo Evidence	6
Whole‐exome sequencing‐based mutational profiling of hepatocellular adenoma malignant transformation to hepatocellular carcinoma	6
GLP‐1 receptor agonist liraglutide alleviates kidney injury by regulating nuclear translocation of NRF2 in diabetic nephropathy	6

Propofol attenuates prostate cancer progression by upregulating TRHDE‐AS1 expression, and METTL14 could mediate its m6A modification	6
Endothelin System Blockade Extenuates Sepsis‐Induced Acute Heart and Kidney Injuries via Modulating ET‐1/Klotho/p38‐MAPK	6
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Ajugoside Promotes the Repair of Osteoporotic Bone by Inducing Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells	6
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Scutellarin inhibits oleic acid induced vascular smooth muscle foam cell formation via activating autophagy and inhibiting NLRP3 inflammasome activation	6
COX17 Attenuates Diabetes‐Associated Retinal Injury by Improving Mitochondrial Function	6
Comprehensive analysis of EphA2 in pan‐cancer: A prognostic biomarker associated with cancer immunity	6
Exosomal miR‐21‐5p derived from multiple myeloma cells promote renal epithelial–mesenchymal transition through targeting TGF‐β/SMAD7 signalling pathway	6
The TNF ‐α– FABP4 –Dhhc7 Axis Mediates Olanzapine‐Induced Insulin Resistance in Rats and Humans	6
Synergic actions of botulinum neurotoxin A and oxaliplatin on colorectal tumour cell death through the upregulation of TRPM2 channel‐mediated oxidative stress	6
Aurora A‐Mediated Exosomal Secretion of miR ‐644a Promotes T‐Lymphocyte Apoptosis Through the NOXA	6
Shikonin ameliorates oxidative stress and neuroinflammation via the Akt/ERK/JNK/NF‐κB signalling pathways in a model of Parkinson's disease	5
Growth hormone‐releasing hormone beyond cancer	5
Restoring Autophagy by Exercise Ameliorates Insulin Resistance Partly via Calcineurin‐Driven TFEB Nuclear Translocation	5
Interaction of mtROS ‐Immune‐Inflammatory Vicious Cycle Activation in Sepsis‐Induced Cardiomyopathy	5
PD‐L1/PD‐L1 signalling promotes colorectal cancer cell migration ability through RAS/MEK/ERK	5
Impact of JAK/STAT inhibitors on human monocyte‐derived‐macrophages stimulated by cigarette smoke extract and lipopolysaccharide	5
Caffeic acid phenethyl ester ameliorates colistin‐induced nephrotoxicity in rats via modulation of FOXO1 /Nrf2/Sirt1 axis	5
Linarin Relieves Apoptosis, Inflammation and Oxidative Stress in LPS‐Induced Acute Kidney Injury by Modulating COX2	5
Tabersonine Alleviates Cerebral Ischemia/Reperfusion Injury Partly via Repressing the SLC6A2 / NF	5
Effectiveness and Safety of Omalizumab in the Adjuvant Treatment of Patients With Refractory Acute Urticaria: A Real‐World Case–Control Study	5
Loganin exerts neuroprotective effect by inhibiting neuronal pyroptosis in rat with cerebral haemorrhage	5
Electroacupuncture Alleviates Focal Cerebral Ischemia–Reperfusion Injury and Is Associated With Modulation of Autophagy‐Ferroptosis Involving the STAT3	5
Disk diffusion‐based method aids in the detection of vanM‐positive Enterococcus faecium with low vancomycin minimum inhibitory concentrations	5
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Study on the anti‐inflammatory effect of stachyose by inhibiting TLR4/NF‐κB signalling pathway in vitro and in vivo	5
Association between dietary inflammation index and inflammatory bowel disease in adults: Results from National Health and Nutrition Examination Survey 2009–2010	5
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Relationship Between Long‐Term Exposure to Airborne Particulate Matter and the Intrinsic Capacity of Middle‐Aged and Older Adults in China: A Retrospective Cohort Study Based on	5
Novel Semisynthetic Derivative of Dehydrozingerone (DHZ‐15) Modulates Lipopolysaccharide‐Stimulated Macrophages by Targeting the NF‐κB/p65 Pathway and In Vivo Evaluati	4
Intravenous haloperidol and cocaine alter the distribution of T CD3+CD4+, non‐T/NK and NKT cells in rats	4
Expression of Concern: High glucose facilitates cell cycle arrest of rat bone marrow multipotent adult progenitor cells through TGF‐β1 and ERK1/2 signaling without change in Oct‐4 expression	4
Dihydromyricetin reverses capecitabine‐induced peripheral myelin dysfunction through modulation of oxidative stress	4
Early and Stable Mouse Model of Amphotericin B‐Induced Acute Kidney Injury: Application of Continuous Non‐Invasive GFR Monitoring	4
Potential roles of ellagic acid on metabolic variables in diabetes mellitus: A systematic review	4
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Dantrolene and ryanodine receptors in COVID‐19: The daunting task and neglected warden	4
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Potential Kidney Risks Associated With Clinical Doses of Omeprazole: In Vivo and In Vitro Studies	4
Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy	4
NOTIFICATION: MiR‐375‐3p/YWHAZ/β‐catenin Axis Regulates Migration, Invasion, EMT in Gastric Cancer Cells	4
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Activation of GPR39 Ameliorates Placental Dysfunction by Inhibiting Activation of NLRP1 Inflammasome in Gestational Diabetes Mellitus	4
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Biochemical Investigation of the Association of Apolipoprotein E Gene Allele Variations with Insulin Resistance and Amyloid‐β Aggregation in Cardiovascular Disease	4
Research trends in ferroptosis since the origin of the concept: A bibliometric analysis	4
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Angiotensin receptor blockade with olmesartan alleviates brain pathology in obese OLETF rats	4
An evodiamine derivative inhibits osteoclast differentiation and protects against OVX‐induced bone loss in mice	4
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Chronic intermittent hypoxia‐induced oxidative stress activates TRB3 and phosphorylated JNK to mediate insulin resistance and cell apoptosis in the pancreas	4
Cancer‐associated fibroblast‐derived circFARP1 modulates non–small cell lung cancer invasion and metastasis through the circFARP1/miR‐338‐3p/SOX4 axis	4
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Application of 3D computed tomography in emphysematous parenchyma patients scheduled for bronchoscopic lung volume reduction	4
Exploring the Protective Role and Regulation of Prdx6 in Cisplatin‐Induced AKI	4
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Brazilin inhibits bladder cancer by promoting cell necroptosis	3
PDZK1 Regulates the Stability and Function of ADRB2 to Prevent Vascular Remodelling in Hypertension	3
Frailty: An Important Determinant Influencing Glycaemic Control in Elderly Chinese Patients Diagnosed With Type 2 Diabetes	3
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Contribution of calcium dysregulation to impaired coronary artery contraction in Zucker diabetic fatty rats	3
Curcumol reduces lower limb arteriosclerosis in rats by inhibiting human arterial smooth muscle cell activity	3
A gain of function ryanodine receptor 2 mutation (R1760W‐RyR2) in catecholaminergic polymorphic ventricular tachycardia	3
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Mitochondrial Oxidative Stress and Cardiac Dysfunction in TERT Deficient Progeria Mice	3
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IL‐4/STAT6 axis observed to reverse proliferative defect in SCA3 patient‐derived neural progenitor cells	3
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Berberine interacts with gut microbiota and its potential therapy for polycystic ovary syndrome	3
An analysis of antithrombotic therapy in elderly patients with atrial fibrillation undergoing percutaneous coronary interventions	3
Inhibition of Bilirubin Generation Exacerbates Oxidative Stress and Liver Injury in Early‐to‐Intermediate Obstructive Cholestasis	3
Anti‐prolactin treatment alleviates lupus conditions by regulating the JAK2–STAT3 pathway	3
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Piezo1 Knockdown Attenuates Hypertension‐Induced Cardiac Fibrosis by Inhibiting Ca 2+ /β‐Catenin Signalling Pathway	3
Diclofenac Enhances the Response of BRAF Inhibitor to Melanoma Through ROS/p38/p53 Signaling	3
β‐Carotene regulates glucose transport and insulin resistance in gestational diabetes mellitus by increasing the expression of SHBG	3

PHD3‐Mediated Inhibition of Retinal Neovascularization in Retinopathy of Prematurity	3
Cynomorium songaricum Rupr. Polysaccharide ( CSP ) Attenuates Diabetic Nephropathy by Activating	3
A non‐antibiotic erythromycin derivative improves muscle endurance by regulating endogenous anti‐fatigue protein orosomucoid in mice	3
Effect of phylloquinone on indomethacin‐induced gastric ulceration in rats: Role of SIRT‐1	3
Synthesis, Characterization, Molecular Dynamic Simulation and Neuroprotective Effects of Synthetic Isoxazolone Derivatives in Ethanol‐Induced Neurodegeneration	3
MRGPRX2‐Mediated Mast Cell Degranulation by Monomethyl Methacrylate: Unveiling a Pathway in Bone Cement Implantation Syndrome	3
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Anatomical Classification and Clinical Significance of Right Middle Lobe Vein Confluence Variations in Right Upper Lobectomy: A Three‐Dimensional Reconstruction Study	2
Ciliatoside A Improves Klebsiella pneumoniae ‐Induced Pneumonia by Modulating Mitochondrial Autoph	2
Cardioprotective potential of vanillic acid	2
Gemfibrozil Prevents Myocardial Ischemia–Reperfusion Injury in Mice Through AMPK Activation	2
Ginsenoside Rg1 Improves Cardiac Function and Ventricular Remodelling by Down‐Regulating SH2B Adaptor Protein 1 Expression in Rats With Myocardial In	2
Predictive Effect of FT3 Within the Euthyroid Range on LDL‐C in Patients With Type 2 Diabetes: A Cross‐Sectional Analysis of Inpatients in China	2
Correction to “Glaucocalyxin A Induces Apoptosis of Non‐Small Cell Lung Carcinoma Cells by Inhibiting the PI3K /Akt/ GSK3β	2
Combination of SVI/S′ and diagnostic scores for heart failure with preserved ejection fraction	2
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Ligustrazine and liguzinediol protect against doxorubicin‐induced cardiomyocytes injury by inhibiting mitochondrial apoptosis and autophagy	2
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Saikosaponin D Alleviates Atherosclerosis by Regulating Autophagy and Senescence of VSMCs via Inhibiting EPHB2	2
Sinomenine Suppresses Hepatocellular Carcinoma Cell Migration and Invasion by Inhibiting O‐GlcNAcylation of SP1	2
Inosine monophosphate dehydrogenase activity and mycophenolate pharmacokinetics in children with nephrotic syndrome treated with mycophenolate mofetil	2
3‐aminohydantoin derivate as a promising scaffold in dopaminergic neuroprotection and neurorescue in the in vivo and in vitro 6‐hydroxydopamine models of Parkinson's disease	2
Uridine phosphorylase‐1 promotes cell viability and cell‐cycle progression in human epidermal keratinocytes via the glycolytic pathway	2
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Bach1 modulates AKT3 transcription to participate in hyperglycaemia‐mediated EndMT in vascular endothelial cells	2
NPAS2, transcriptionally activated by ARRB1, promotes the malignant behaviours of lung adenocarcinoma cells and regulates the reprogramming of glucose metabolism	2
Kaempferol Suppresses Mesothelial–Mesenchymal Transition and Attenuates Postoperative Peritoneal Adhesions by Blocking the TNF‐α/COX2 Signalling Pathway	2
Combining γ‐GT, PIVKA‐II, and AFP to predict long‐term prognosis in patients with hepatocellular carcinoma after hepatectomy	2
Ginsenoside Rh1 regulates gastric cancer cell biological behaviours and transplanted tumour growth in nude mice via the TGF‐β/Smad pathway	2
Inhibition of Hsp90 Alleviates Necroptosis and Inflammation in Lung Epithelial Cells During Pulmonary Ischemia–Reperfusion Injury	2
Prophylactic Effects of Rhamnetin Flavonoid on Indomethacin‐Induced Gastric Ulceration by Modulating HSP 70/Bax, SOD/MDA and TNF‐α/IL‐10	2
Improved cardioprotective effect of 3‐nitro‐N‐methyl salicylamide solution after a prolonged preservation time of rat heart	2
Oroxin B Resembles Bisoprolol in Attenuating Beta1‐Adrenergic Receptor Autoantibody‐Induced Atrial Remodelling via the PTEN/AKT/mTOR Signalling Pathway	2
Mechanism of ligusticum cycloprolactam against neuroinflammation based on network pharmacology and experimental verification	2
Limited sampling strategy to predict free mycophenolic acid area under the concentration–time curve in paediatric patients with nephrotic syndrome	2
Clinical Analysis of Pulmonary Nontuberculous Mycobacterial Infection in Patients With Pre‐Existing Stage II–IV Lung Cancer	2
The Rough Morphotype of Mycobacterium abscessus Enhances Its Virulence Through ROS/p65/NLRP3/GSDMD‐Mediated Macrophage Pyroptosis	2
Noninvasively Evaluating the Cerebral Blood Flow Changes After Surgery in Adult Moyamoya Patients Using 3D Pulsed Arterial Spin Labelling	2
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Colorectal cancer cells with stably expressed SIRT3 demonstrate proliferating retardation by Wnt/β‐catenin cascade inactivation	2
Dapagliflozin alleviates high glucose‐induced injury of endothelial cells via inducing autophagy	1
Amnion membranes support wound granulation in a delayed murine excisional wound model	1
Relative refractoriness of breast cancer cells to tumour necrosis factor‐α induced necroptosis	1
D‐pinitol attenuates isoproterenol‐induced myocardial infarction by alleviating cardiac inflammation, oxidative stress and ultrastructural changes in Swiss albino mice	1
The ELF1 / IGF2BP2 / FAM111B Cascade Drives Col	1
Bharangin, A Diterpenoid, Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine Through Involvement of Long Non‐Coding RNAs and Nuclear Factor‐κB	1
The role and therapeutic applications of exosomes in multiple sclerosis disease	1
Attenuation of Vascular Dementia Associated Neuroinflammation by Inhibition of the JNK Pathway in HFD	1
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Adenylate cyclase 1 knockdown attenuates pirarubicin‐induced cardiotoxicity	1
Differential responses of cerebral and renal oxygenation to altered perfusion conditions during experimental cardiopulmonary bypass in sheep	1
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TRMT13 Facilitates SPAST Upregulation Through ceRNA Crosstalk and M	1
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Stachydrine Protects Against Cyclophosphamide‐Induced Premature Ovarian Insufficiency in Wistar Rats by Inhibiting Oxidative Stress and Apoptosis via the Activation of the Nrf2/HO‐1 Signall	1
Docosahexaenoic acid alleviates the excessive degradation of extracellular matrix in the nucleus pulposus by reducing the content of lncRNA NEAT1 to prevent the progression of intervertebra	1
CircADSS contributes to hepatocellular carcinoma development by regulating miR‐431‐5p/TOP2A	1
Aucubin alleviates methotrexate‐induced enteritis in rats by inducing autophagy	1
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Inhibition of DNA Methyltransferase DNMT1 Reverses Th2 Response Polarisation and Alleviates Allergic Rhinitis	1
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A Novel Inhibitor of Methyltransferase SMYD2, AZ505 Protects Against Peritoneal Fibrosis in Mice	1
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Dapagliflozin Improves Mitochondrial Function to Reduce the Risk of Atrial Fibrillation in a High‐Glucose Environment by Activating the AMPK/PGC‐1α/SIRT3	1
An integrated bioinformatics analysis reveals IRF8 as a critical biomarker for immune infiltration in atherosclerosis advance	1
Extrinsic apoptosis and senescence involved in growth kinetics of seminoma to cisplatin	1
Evaluation of right atrium structure and function in a rat model of monocrotaline‐induced pulmonary hypertension: Exploring the possible antiarrhythmic properties of amiodarone	1
Prevalence and Associated Factors of Anxiety and Depression in Lung Cancer Patients	1
Hsa_circ_0000591 drives osteosarcoma glycolysis and progression by sequestering miR‐194‐5p and elevating HK2 expression	1
METTL3 ‐Mediated m6A Modification Facilitates pri‐ miR ‐221 Maturat	1
Acepromazine Reduces Airway Contraction in a Murine Model of Asthma	1
Comparison of disease‐modifying anti‐rheumatic drugs and hyperbaric oxygen therapy in the experimental model of rheumatoid arthritis in rats	1
Immunoregulation by resveratrol; implications for normal tissue protection and tumour suppression	1
Kisspeptin‐10 Preserves the Blood‐Brain Barrier's Integrity Post‐Stroke by Augmenting Claudin‐10 Expression	1
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Chlorogenic Acid Improves Salicylic Acid‐Induced Cochlear Injury by Reducing Oxidative Stress and Inflammatory Response Through TLR4/NF‐κB Signalling Pathway	1
The Health Education During Root Canal Therapy Reduces the Use of Antibiotics	1