Archives of Toxicology

Article	Citations
In vitro approaches to investigate the effect of chemicals on antibody production: the case study of PFASs	800
Application of in silico methods to predict the acute toxicity of bicyclic organophosphorus compounds as potential chemical weapon	229
7-Hydroxycannabidiol and 7-carboxycannabidiol induced cytotoxicity via apoptosis and endoplasmic reticulum stress in human hepatic cells	224
Replication stress: an early key event in ochratoxin a genotoxicity?	164
Comprehensive ubiquitome analysis reveals persistent mitochondrial remodeling disruptions from doxorubicin-induced cardiotoxicity in aged CD-1 male mice	138
Optimized methods for measuring competitive binding of chemical substances to thyroid hormone distributor proteins transthyretin and thyroxine binding globulin	125
Multi-omics bioactivity profile-based chemical grouping and read-across: a case study with Daphnia magna and azo dyes	108
Are the current commercially available oximes capable of reactivating acetylcholinesterase inhibited by the nerve agents of the A-series?	100
Interplay between proteasome function and inflammatory responses in e-cig vapor condensate-challenged lung epithelial cells	90
A modular strategy for the testing and assessment of non-genotoxic carcinogens	86
Disentangling the role of selenium in antagonizing the toxicity of arsenic and cadmium	82
US regulations to curb alleged cancer causes are ineffectual and compromised by scientific, constitutional and ethical violations	80
Unanticipated differences in the rat plasma metabolome of genistein and daidzein	75
A comparative toxicological evaluation of emerging nicotine analogs 6-methyl nicotine and nicotinamide: a scoping review	72
Non-invasive in vitro NAM for the detection of reversible and irreversible eye damage after chemical exposure for GHS classification purposes (ImAi)	68
The EU chemicals strategy for sustainability: critical reflections on proposed regulatory changes for endocrine disruptors and mixture toxicity	66
Accumulation of chlorinated paraffins in adipocytes is determined by cellular lipid content and chlorination level	66
Comparative case study on NAMs: towards enhancing specific target organ toxicity analysis	62
Effects of postnatal exposure to tetrabromobisphenol A on testis development in mice and early key events	62
Dynamics in zebrafish development define transcriptomic specificity after angiogenesis inhibitor exposure	56
Trends in research on advanced glycation end products (AGEs)	55
Progress in protecting vestibular hair cells	55
Screening for ferroptosis genes related to endometrial carcinoma and predicting of targeted drugs based on bioinformatics	55
Development of human growth hormone-treated chimeric mice with humanized livers for an evaluation model of drug-induced fatty liver disease	54
Influence of deoxynivalenol and zearalenone on the immunohistochemical expression of oestrogen receptors and liver enzyme genes in vivo in prepubertal gilts	53

Chronic oral exposure to low-concentration fumonisin B2 significantly exacerbates the inflammatory responses of allergies in mice via inhibition of IL-10 release by regulatory T cells in gut-associate	52
Pharmacogenetics in early drug development for non-alcoholic steatohepatitis: missed chances and future opportunities	52
Issue analysis: key characteristics approach for identifying endocrine disruptors	51
Activation of (un)regulated cell death as a new perspective for bispyridinium and imidazolium oximes	51
Paternal lipopolysaccharide exposure induced intrauterine growth restriction via the inactivation of placental MEST/PI3K/AKT pathway in mice	50
Orphan nuclear receptor ERRγ regulates hepatic TGF-β2 expression and fibrogenic response in CCl4-induced acute liver injury	46
Microarray analysis of gene expression in lung tissues of indium-exposed rats: possible roles of S100 proteins in lung diseases	45
The estimation of acute oral toxicity (LD50) of G-series organophosphorus-based chemical warfare agents using quantitative and qualitative toxicology in silico methods	45
PBTK model-based analysis of CYP3A4 induction and the toxicokinetics of the pyrrolizidine alkaloid retrorsine in man	44
Drug-induced hepatic sinusoidal obstruction syndrome: current advances and future perspectives	44
Physiologically-based pharmacokinetic model for evaluating gender-specific exposures of N-nitrosodimethylamine (NDMA)	43
Exposure limits for indoor volatile substances concerning the general population: The role of population-based differences in sensory irritation of the eyes and airways for assessment factors	42
In vitro assessment of thyroid peroxidase inhibition by chemical exposure: comparison of cell models and detection methods	39
Investigating the applicability domain of the hiPSC-based PluriLum assay: an embryotoxicity assessment of chemicals and drugs	39
A multi-omics approach to elucidate okadaic acid-induced changes in human HepaRG hepatocarcinoma cells	38
Female offspring of mice perinatally exposed to benzophenone-3 showed early subfertility linked to a poor oocyte stockpile	37
Vascular endothelial dysfunction induced by 3-bromofluoranthene via MAPK-mediated-NFκB pro-inflammatory pathway and intracellular ROS generation	36
Metabolism of alcohol ethoxylates (AEs) in rat, hamster, and human hepatocytes and liver S9: a pilot study for metabolic stability, metabolic pathway, and metabolites identification in vitro and in si	35
Author Correction: Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health	34
Synthesis and in vitro assessment of the reactivation profile of clinically available oximes on the acetylcholinesterase model inhibited by A-230 nerve agent surrogate	34
CYP2E1 in 1,4-dioxane metabolism and liver toxicity: insights from CYP2E1 knockout mice study	34
The tyrosine kinase inhibitor LPM4870108 impairs learning and memory and induces transcriptomic and gene‑specific DNA methylation changes in rats	33
Sepsis-induced cardiomyopathy: understanding pathophysiology and clinical implications	33
Molecular mechanisms of environmental pollutant-induced cartilage damage: from developmental disorders to osteoarthritis	32
The Bach1/HO-1 pathway regulates oxidative stress and contributes to ferroptosis in doxorubicin-induced cardiomyopathy in H9c2 cells and mice	32
Evaluation of the cyto- and genotoxicity of two types of cellulose nanomaterials using human intestinal cells and in vitro digestion simulation	31
Minimum information for reporting on the TEER (trans-epithelial/endothelial electrical resistance) assay (MIRTA)	31
Cell–cell contacts prevent t-BuOOH-triggered ferroptosis and cellular damage in vitro by regulation of intracellular calcium	31
Elevated blood-ethanol concentration promotes reduction of aliphatic ketones (acetone and ethyl methyl ketone) to secondary alcohols along with slower oxidation to aliphatic diols	31
Medaka embryos as a model for metabolism of anabolic steroids	31
Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds—a hypo	30
Hypertension toxicity of VEGFR-TKIs in cancer treatment: incidence, mechanisms, and management strategies	30
Genotoxicity evaluation of nitrosamine impurities using human TK6 cells transduced with cytochrome P450s	29
Effects of chronic insecticide exposure on neuronal network development in vitro in rat cortical cultures	29
Discovery of the Alternaria mycotoxins alterperylenol and altertoxin I as novel immunosuppressive and antiestrogenic compounds in vitro	29
The entactogen 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) as a treatment aid in psychotherapy and its safety concerns	28
Cannabidivarin and cannabigerol induce unfolded protein response and angiogenesis dysregulation in placental trophoblast HTR-8/SVneo cells	28
A multi-biomarker micronucleus assay using imaging flow cytometry	28
TRPM7 restrains plasmin activity and promotes transforming growth factor-β1 signaling in primary human lung fibroblasts	27
Carbon nanotubes conjugated with cisplatin activate different apoptosis signaling pathways in 2D and 3D-spheroid triple-negative breast cancer cell cultures: a comparative study	27
Effects of carbon black particles on human monocyte-derived macrophages: type-dependent pro-inflammatory activation in vitro	27
The food-borne carcinogenic 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) disrupts circadian rhythms and ameliorated by pterostilbene (PSB) in Caenorhabditis elegans	27
Scientific discrepancies in European regulatory proposals on endocrine disruptors—REACH regulation quo vadis?	26
The role of hypoxia-inducible factor 1 alpha (HIF-1α) modulation in heavy metal toxicity	25
Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity	25
Avicenna’s clinical toxicology approach and beneficial materia medica against oral poisoning	25
Altered metabolic pathways elucidated via untargeted in vivo toxicometabolomics in rat urine and plasma samples collected after controlled application of a human equivalent amphetamine dose	25
In vitro modeling of liver fibrosis in 3D microtissues using scalable micropatterning system	24
Exposure of intestinal explants to NX, but not to DON, enriches the secretome in mitochondrial proteins	24
Developing urinary pyrrole–amino acid adducts as non-invasive biomarkers for identifying pyrrolizidine alkaloids-induced liver injury in human	24

Exposure to the mycotoxin deoxynivalenol reduces the transport of conjugated bile acids by intestinal Caco-2 cells	23
Connexins may play a critical role in cigarette smoke-induced pulmonary hypertension	23
Hepatic metabolism of chlorinated derivatives of bisphenol A (ClxBPA) and interspecies differences between rats and humans	23
Chicken heterophils extracellular traps act as early effectors against cyclopiazonic acid dependent upon NADPH oxidase, ROS and glycolysis	23
OCT1-dependent uptake of structurally diverse pyrrolizidine alkaloids in human liver cells is crucial for their genotoxic and cytotoxic effects	22
rVSV-ΔG-SARS-CoV-2-S vaccine: repeated intramuscular (IM) toxicity, local tolerance, immunogenicity and biodistribution study in NZW rabbits	22
Rhazes's methodology in the science of toxicology	22
In vitro and in vivo protective potential of quercetin-3-glucuronide against lipopolysaccharide-induced pulmonary injury through dual activation of nuclear factor-erythroid 2 related factor 2 and auto	22
Induction of clastogenesis and gene mutations by carbamazepine (at its therapeutically effective serum levels) in mammalian cells and the dependence on human CYP2B6 enzyme activity	22
Towards the mechanism of spermatotoxicity of p-tert-butyl-alpha-methylhydrocinnamic aldehyde: inhibition of late stage ex-vivo spermatogenesis in rat seminiferous tubule cultures by para-tert-butyl- b	22
Immunomodulation and exposure to per- and polyfluoroalkyl substances: an overview of the current evidence from animal and human studies	22
Developmental brain lipidomics is influenced by postnatal chlorpyrifos exposure and APOE genetic background in mice	21
Bisphenol A and its analogues: from their occurrence in foodstuffs marketed in Europe to improved monitoring strategies—a review of published literature from 2018 to 2023	21
Comparison of comet-based approaches to assess base excision repair	21
N-acetyltransferase 2 genetic polymorphism modifies genotoxic and oxidative damage from new psychoactive substances	21
Unraveling the AKT/ERK cascade and its role in Parkinson disease	21
Effects of novel flame retardants tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) and triphenyl phosphate (TPhP) on function and homeostasis in human and rat pancreatic beta-cell lines	21
Toxicokinetics of 2-ethylhexyl salicylate (EHS) and its seven metabolites in humans after controlled single dermal exposure to EHS	21
Hepatoprotective effects of phytochemicals and plant extracts against chemotherapy-induced liver damage in animal models: a systematic review	20
Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity	20
SIRT3/GLUT4 signaling activation by metformin protect against cisplatin-induced ototoxicity in vitro	20
Role of miR-24-3p and miR-146a-5p in dendritic cells’ maturation process induced by contact sensitizers	20
Establishment of a human 3D in vitro liver-bone model as a potential system for drug toxicity screening	20
Subcellular spatio-temporal intravital kinetics of aflatoxin B1 and ochratoxin A in liver and kidney	19
Dopaminergic and serotonergic changes in rabbit fetal brain upon repeated gestational exposure to diesel engine exhaust	19
Genetic variations in the CTLA-4 immune checkpoint pathway are associated with colon cancer risk, prognosis, and immune infiltration via regulation of IQCB1 expression	19
Short-term repeated oral intake of low dose cannabidiol: effects on liver enzyme activity and creatinine concentration during intense exercise	19
Estimating the reduction in US mortality if cigarettes were largely replaced by e-cigarettes	19
Novel insight into mechanisms for ATR activation by chromatin structures	19
The Janus face of uranium in toxicology	19
Opinion: A serious issue with the standardization of the adenovirus-based COVID-19 vaccines?	19
Mechanistic perspectives on differential mitochondrial-based neuroprotective effects of several carnitine forms in Alzheimer’s disease in vitro model	19
New aspects in snake venom toxicology	19
Feeding Brassica vegetables to rats leads to the formation of characteristic DNA adducts (from 1-methoxy-3-indolylmethyl glucosinolate) in many tissues	19
Toxicokinetics of plasmatic VX in a swine model: comparison of a simple enzymatic titration method with a mass spectrometry method	18
The EU chemicals strategy for sustainability: in support of the BfR position	18
Species differences and human relevance of the toxicity of 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitors and a new approach method in vitro for investigation	18
Correction to: Practical application of the interim internal threshold of toxicological concern (iTTC): a case study based on clinical data	18
Characterization of drug-induced liver injury associated with drug reaction with eosinophilia and systemic symptoms in two prospective DILI registries	18
A comparison of thyroidal protection by iodine and perchlorate against radioiodine exposure in Caucasians and Japanese	18
Differential impact of JUUL flavors on pulmonary immune modulation and oxidative stress responses in male and female mice	18
Cardiovascular responses of adult male Sprague–Dawley rats following acute organophosphate intoxication and post-exposure treatment with midazolam with or without allopregnanolone	18
Structure-based virtual screening of CYP1A1 inhibitors: towards rapid tier-one assessment of potential developmental toxicants	18
Reply to the opinion paper “The EU chemicals strategy for sustainability: an opportunity to develop new approaches for hazard assessment” by Scholz et al.	18
Role of hepcidin in oxidative stress and cell death of cultured mouse renal collecting duct cells: protection against iron and sensitization to cadmium	18
Strategies for enhanced bioavailability of oxime reactivators in the central nervous system	18
Cytogenotoxicity and inflammatory response in liver of rats exposed to different doses of cannabis nano emulsions	18
Aryl hydrocarbon receptor (AHR) functions in infectious and sterile inflammation and NAD+-dependent metabolic adaptation	18
Response to Dr. Reutova regarding the Letter to the Editor titled ‘What are the criteria and conditions for performing the micronucleus assay in oral exfoliated cells from children continuously expose	17
Mouse innate-like B-1 lymphocytes promote inhaled particle-induced in vitro granuloma formation and inflammation in conjunction with macrophages	17
Cannabidiol disrupts apoptosis, autophagy and invasion processes of placental trophoblasts	17
Evaluation of functional candidate biomarkers of non-genotoxic hepatocarcinogenicity in human liver spheroid co-cultures	17
The effect of alkyl substitution on the oxidative metabolism and mutagenicity of phenanthrene	17
Impact of endocrine disruptors on peripheral blood mononuclear cells in vitro: role of gender	17
Cysteine conjugates of acetaminophen and p-aminophenol are potent inducers of cellular impairment in human proximal tubular kidney HK-2 cells	17
Androgenic properties of the dietary supplement 5α-hydroxy-laxogenin	16
Monitoring of per- and polyfluoroalkyl substances (PFAS) in human blood samples collected in three regions with known PFAS releases in the environment and three control regions in South Germany	16
Gasdermin D membrane pores orchestrate IL-1α secretion from necrotic macrophages after NFS-rich silica exposure	16
Involvement of per- and polyfluoroalkyl compounds in tumor development	16
Basic concepts of mixture toxicity and relevance for risk evaluation and regulation	16
Arylacetamide deacetylase regulates hepatic iron homeostasis to protect against carbon tetrachloride-induced ferroptosis	16
miR-451a and miR-486-5p: biomarkers for benzene-induced hematotoxicity	16
Environmental barium: potential exposure and health-hazards	16
Assessing the role of the gut microbiome in methylmercury demethylation and elimination in humans and gnotobiotic mice	16
Titanium dioxide nanoparticles: revealing the mechanisms underlying hepatotoxicity and effects in the gut microbiota	16
Nitrofurantoin-induced liver injury: long-term follow-up in two prospective DILI registries	16
Use of innovative, cross-disciplinary in vitro, in silico and in vivo approaches to characterize the metabolism of chloro-alpha-pyrrolidinovalerophenone (4-Cl-PVP)	16
Reply to the opinion paper “The impact of stress on rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide: some theoretical concepts for scientific debate” by Silva et al.	16
Mystery of methamphetamine-induced autophagosome accumulation in hippocampal neurons: loss of syntaxin 17 in defects of dynein–dynactin driving and autophagosome–late endosome/lysosome fusion	16
Mammalian toxicity of trifluoroacetate and assessment of human health risks due to environmental exposures	16
Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models	16
Effects of co-formulants on the absorption and secretion of active substances in plant protection products in vitro	15
In silico analysis decodes transthyretin (TTR) binding and thyroid disrupting effects of per- and polyfluoroalkyl substances (PFAS)	15
Neonatal opioid toxicity: opioid withdrawal (abstinence) syndrome with emphasis on pharmacogenomics and respiratory depression	15
Replacement of animal testing by integrated approaches to testing and assessment (IATA): a call for in vivitrosi	15
Oral nicotine pouches with an aftertaste? Part 1: screening and initial toxicological assessment of flavorings and other ingredients	15
Metabolic dysfunction-associated steatotic liver disease-induced changes in the antioxidant system: a review	15
Mechanistic safety assessment via multi-omic characterisation of systemic pathway perturbations following in vivo MAT2A inhibition	15
Single-cell RNA sequencing to reveal non-parenchymal cell heterogeneity and immune network of acetaminophen-induced liver injury in mice	15
Characterization of pathological changes in the olfactory system of mice exposed to methylmercury	15

Prothioconazole induces cell cycle arrest by up-regulation of EIF4EBP1 in extravillous trophoblast cells	14
Cancer drug resistance induced by EMT: novel therapeutic strategies	14
A framework for establishing scientific confidence in new approach methodologies	14
A novel approach to calculating the kinetically derived maximum dose	14
Grouping of chemicals for safety assessment: the importance of toxicokinetic properties of salicylate esters	14
The diarrhetic shellfish-poisoning toxin, okadaic acid, provokes gastropathy, dysbiosis and susceptibility to bacterial infection in a non-rodent bioassay, Galleria mellonella	14
A walk in the PARC: developing and implementing 21st century chemical risk assessment in Europe	14
Impaired intestinal stem cell activity in ETEC infection: enterotoxins, cyclic nucleotides, and Wnt signaling	14
Methanol-induced optic neuropathy: a still-present problem	14
Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids	13
The fungicide propiconazole induces hepatic steatosis and activates PXR in a mouse model of diet-induced obesity	13
A review of cardiovascular effects and underlying mechanisms of legacy and emerging per- and polyfluoroalkyl substances (PFAS)	13
Heavy metals: toxicity and human health effects	13
Assessment of multiple mycotoxin exposure and its association with food consumption: a human biomonitoring study in a pregnant cohort in rural Bangladesh	13
Biodistribution and intestinal inflammatory response following voluntary oral intake of silver nanoparticles by C57BL/6J mice	13
Morphological alterations in C57BL/6 mouse intestinal organoids as a tool for predicting chemical-induced toxicity	13
Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose	13
Thifluzamide exposure induced neuro-endocrine disrupting effects in zebrafish (Danio rerio)	13
Sirtuins as molecular targets, mediators, and protective agents in metal-induced toxicity	13
Systematic evaluation of high-throughput PBK modelling strategies for the prediction of intravenous and oral pharmacokinetics in humans	13
Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging	13
Contribution to the ongoing discussion on fluoride toxicity	13
Ferroptosis as a mechanism of non-ferrous metal toxicity	13
From hazard to risk prioritization: a case study to predict drug-induced cholestasis using physiologically based kinetic modeling	13
Molecular insights into the pathophysiology of doxorubicin-induced cardiotoxicity: a graphical representation	13
In vitro-in silico analysis reveals that loss of tankyrase1/2 improves bile acid handling in genetically engineered HepG2 cultures	12
Yttrium chloride-induced cytotoxicity and DNA damage response via ROS generation and inhibition of Nrf2/PPARγ pathways in H9c2 cardiomyocytes	12
Predicting the in vivo developmental toxicity of benzo[a]pyrene (BaP) in rats by an in vitro–in silico approach	12
Inter-laboratory automation of the in vitro micronucleus assay using imaging flow cytometry and deep learning	12
Development of an adverse outcome pathway network for breast cancer: a comprehensive representation of the pathogenesis, complexity and diversity of the disease	12
In vitro studies on the dependence of drug deposition in dentin on drug concentration, contact time, and the physicochemical properties of the drugs	12
Genome-wide functional integration identified MAZ-controlled RPS14 dysregulation in hepatocellular carcinoma	12
Canine coronavirus infection is intensified by 2,3,7,8-tetrachlorodibenzo-p-dioxin	12
Proteomic profiling of murine biliary-derived hepatic organoids and their capacity for drug disposition, bioactivation and detoxification	12
Aristolochic acid IVa forms DNA adducts in vitro but is non-genotoxic in vivo	12
Dimeric oxyberberine CT4-1 targets LINC02331 to induce cytotoxicity and inhibit chemoresistance via suppressing Wnt/β-catenin signaling in hepatocellular carcinoma	12
Determination of in vitro hepatotoxic potencies of a series of perfluoroalkyl substances (PFASs) based on gene expression changes in HepaRG liver cells	12
Laser vs. thermal treatments of green pigment PG36: coincidence and toxicity of processes	12
Long-term in vitro recording of cardiac action potentials on microelectrode arrays for chronic cardiotoxicity assessment	12
Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging	12
Targeting erythrocyte-mediated hypoxia to alleviate lung injury induced by pyrrolizidine alkaloids	12
In vitro interactions of Alternaria mycotoxins, an emerging class of food contaminants, with the gut microbiota: a bidirectional relationship	12
Dynamically monitoring cellular γ-H2AX reveals the potential of carcinogenicity evaluation for genotoxic compounds	12
One-step extraction and determination of 513 psychoactive substances, drugs, and their metabolites from hair by LC–MS/MS	12
iNKT17 cells play a pathogenic role in ethinylestradiol-induced cholestatic hepatotoxicity	11
Ensemble machine learning to evaluate the in vivo acute oral toxicity and in vitro human acetylcholinesterase inhibitory activity of organophosphates	11
Assessment of aromatic amides in printed food contact materials: analysis of potential cleavage to primary aromatic amines during simulated passage through the gastrointestinal tract	11
In vitro metabolism of helenalin and its inhibitory effect on human cytochrome P450 activity	11
Toxicokinetics of homosalate in humans after dermal application: applicability of oral-route data for exposure assessment by human biomonitoring	11
Toxicology of 3-monochloropropane-1,2-diol and its esters: a narrative review	11
N-acetyltransferase 2 acetylator genotype-dependent N-acetylation and toxicity of the arylamine carcinogen β-naphthylamine in cryopreserved human hepatocytes	11
Non-clinical immunogenicity, biodistribution and toxicology evaluation of a chimpanzee adenovirus-based COVID-19 vaccine in rat and rhesus macaque	11
The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment	11
Combined biological effects and lung proteomics analysis in mice reveal different toxic impacts of electronic cigarette aerosol and combustible cigarette smoke on the respiratory system	11
Investigation of parenteral nutrition-induced hepatotoxicity using human liver spheroid co-cultures	11
Identification of reversible OATP1B1 and time-dependent CYP3A4 inhibition as the major risk factors for drug-induced cholestasis (DIC)	11
Chronic bisphenol A exposure triggers visual perception dysfunction through impoverished neuronal coding ability in the primary visual cortex	11
Functional variants of RPS6KB1 and PIK3R1 in the autophagy pathway genes and risk of bladder cancer	11
Sarin: a never-ending story	11
A review of the success and challenges in characterizing human dermal exposure to flame retardants	10
Fasting augments pyrrolizidine alkaloid-induced hepatotoxicity	10
Does a carboxamide moiety alter the toxicokinetics of synthetic cannabinoids? A study after pulmonary and intravenous administration of cumyl-5F-P7AICA to pigs	10
Multi-organ developmental toxicity and its characteristics in fetal mice induced by dexamethasone at different doses, stages, and courses during pregnancy	10
A fast and reliable method for monitoring genomic instability in the model organism Caenorhabditis elegans	10
Particulate and drug-induced toxicity assessed in novel quadruple cell human primary hepatic disease models of steatosis and pre-fibrotic NASH	10
Influence of pregnancy and non-fasting conditions on the plasma metabolome in a rat prenatal toxicity study	10
In silico structural and mechanistic sights into the N-glycosidase mechanism of Shiga toxin	10
Future in the past: paternal reprogramming of offspring phenotype and the epigenetic mechanisms	10
Glyphosate exposure induces synaptic impairment in hippocampal neurons and cognitive deficits in developing rats	10
The electrophysiological effects of cannabidiol on action potentials and transmembrane potassium currents in rabbit and dog cardiac ventricular preparations	10
Integrated data from intravital imaging and HPLC–MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats	10
Application of physiologically based (PBK) modeling to quantify the effect of the antibiotic tobramycin on bile acid levels in human plasma	10
Identification and characterization of potent, selective, and efficacious inhibitors of human arylamine N-acetyltransferase 1	10
The characteristics, occurrence, and toxicological effects of alternariol: a mycotoxin	9
PBTK modeling of the pyrrolizidine alkaloid retrorsine to predict liver toxicity in mouse and rat	9
Transforming toxins into treatments: the revolutionary role of α-amanitin in cancer therapy	9
Newly discovered letter: why Muller failed to cite the negative mouse mutation findings of Snell, preserving his chances to receive the Nobel Prize	9
The current state of EVALI research (electronic cigarettes or vaping product use-associated lung injury)	9
Mouse precision-cut liver slices as an ex vivo model to study drug-induced cholestasis	9
Nε-(1-Carboxymethyl)-L-lysine, an advanced glycation end product, exerts malignancy on chondrosarcoma via the activation of cancer stemness	9
Role of paraoxonase 1 in organophosphate G-series nerve agent poisoning and future therapeutic strategies	9
Effects of drug-drug interactions and CYP3A4 variants on alectinib metabolism	9
Considerations for the optimization of in vitro models of chloropicrin toxicity	9
Correction to: Screening for ferroptosis genes related to endometrial carcinoma and predicting of targeted drugs based on bioinformatics	9
Antineoplastic therapy affects the in vitro phenotype and functionality of healthy human bone marrow-derived mesenchymal stromal cells	9
Cellular mechanisms of copper neurotoxicity in human, differentiated neurons	9
Development of an in chemico high-throughput screening method for the identification of skin sensitization potential	9
Rapid quantitative high-throughput mouse embryoid body model for embryotoxicity assessment	9
Impact of plastic-related compounds on the gene expression signature of HepG2 cells transfected with CYP3A4	9
A new human autologous hepatocyte/macrophage co-culture system that mimics drug-induced liver injury–like inflammation	9
The evaluation of skin sensitization potential of the UVCB substance diisopentyl phthalate by in silico and in vitro methods	9
Mechanistic insight of neurodegeneration due to micro/nano-plastic-induced gut dysbiosis	9
The role of ferroptosis in cardio-oncology	9
The “EU chemicals strategy for sustainability” questions regulatory toxicology as we know it: is it all rooted in sound scientific evidence?	9
Biotransformation and toxicokinetics of 2-phenoxyethanol after oral exposure in humans: a volunteer study	9