Archives of Toxicology

Article	Citations
Recent aspects of the effects of zinc on human health	284
Inhibition and induction of CYP enzymes in humans: an update	169
Drug induced liver injury: an update	131
Toxicology and pharmacology of synthetic organoselenium compounds: an update	130
Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses	110
Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging	102
Organophosphorus compounds and oximes: a critical review	101
Interactions of polystyrene nanoplastics with in vitro models of the human intestinal barrier	98
Mode of action-based risk assessment of genotoxic carcinogens	98
Cancer drug resistance induced by EMT: novel therapeutic strategies	97
Arsenic intoxication: general aspects and chelating agents	76
Environmental barium: potential exposure and health-hazards	71
Chemical carcinogen safety testing: OECD expert group international consensus on the development of an integrated approach for the testing and assessment of chemical non-genotoxic carcinogens	69
Quantitative adverse outcome pathway (qAOP) models for toxicity prediction	65
A framework for establishing scientific confidence in new approach methodologies	65
An updated review on synthetic cathinones	61
Cross-species analysis of hepatic cytochrome P450 and transport protein expression	56
Cadmium induces renal inflammation by activating the NLRP3 inflammasome through ROS/MAPK/NF-κB pathway in vitro and in vivo	56
Current EU regulatory requirements for the assessment of chemicals and cosmetic products: challenges and opportunities for introducing new approach methodologies	54
Perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorononanoic acid (PFNA) increase triglyceride levels and decrease cholesterogenic gene expression in human HepaRG liver c	54
The functions and regulation of heat shock proteins; key orchestrators of proteostasis and the heat shock response	53
Prediction reliability of QSAR models: an overview of various validation tools	52
An update on T-2 toxin and its modified forms: metabolism, immunotoxicity mechanism, and human exposure assessment	50
Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) induce epigenetic alterations and promote human breast cell carcinogenesis in vitro	49
Prediction of oral hepatotoxic dose of natural products derived from traditional Chinese medicines based on SVM classifier and PBPK modeling	48

Toxicities of opioid analgesics: respiratory depression, histamine release, hemodynamic changes, hypersensitivity, serotonin toxicity	47
Adverse outcome pathways for ionizing radiation and breast cancer involve direct and indirect DNA damage, oxidative stress, inflammation, genomic instability, and interaction with hormonal regulation	46
Human Family 1–4 cytochrome P450 enzymes involved in the metabolic activation of xenobiotic and physiological chemicals: an update	46
Comparing in vitro human liver models to in vivo human liver using RNA-Seq	46
Revisiting the evidence for genotoxicity of acrylamide (AA), key to risk assessment of dietary AA exposure	45
Hypoxia, oxidative stress, and immune evasion: a trinity of the trichothecenes T-2 toxin and deoxynivalenol (DON)	44
Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose	43
Acute, reproductive, and developmental toxicity of essential oils assessed with alternative in vitro and in vivo systems	42
Antidepressants- and antipsychotics-induced hepatotoxicity	42
The evolution of strategies to minimise the risk of human drug-induced liver injury (DILI) in drug discovery and development	42
Origins, fate, and actions of methylated trivalent metabolites of inorganic arsenic: progress and prospects	41
A framework for chemical safety assessment incorporating new approach methodologies within REACH	41
Toxicokinetics and metabolism of deoxynivalenol in animals and humans	40
Wogonin induces cellular senescence in breast cancer via suppressing TXNRD2 expression	40
Glutaminases regulate glutathione and oxidative stress in cancer	40
Biotransformation of arsenic and toxicological implication of arsenic metabolites	39
ROS-induced lipid peroxidation modulates cell death outcome: mechanisms behind apoptosis, autophagy, and ferroptosis	39
Functional alterations by a subgroup of neonicotinoid pesticides in human dopaminergic neurons	37
Krebs cycle: activators, inhibitors and their roles in the modulation of carcinogenesis	36
Mechanisms of deoxynivalenol-induced endocytosis and degradation of tight junction proteins in jejunal IPEC-J2 cells involve selective activation of the MAPK pathways	36
Molecular insights into the pathophysiology of doxorubicin-induced cardiotoxicity: a graphical representation	36
Artificial intelligence and machine learning disciplines with the potential to improve the nanotoxicology and nanomedicine fields: a comprehensive review	36
In vitro functional characterization of a panel of non-fentanyl opioid new psychoactive substances	35
Methanol-induced optic neuropathy: a still-present problem	35
3D bioprinting of complex tissues in vitro: state-of-the-art and future perspectives	35
Nrf2 deficiency aggravates the kidney injury induced by subacute cadmium exposure in mice	35
Gadolinium: pharmacokinetics and toxicity in humans and laboratory animals following contrast agent administration	35
Metabolism-mediated cytotoxicity and genotoxicity of pyrrolizidine alkaloids	35
Organophosphorus flame retardants are developmental neurotoxicants in a rat primary brainsphere in vitro model	33
Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals	32
Dapagliflozin suppresses ER stress and protects doxorubicin-induced cardiotoxicity in breast cancer patients	32
A walk in the PARC: developing and implementing 21st century chemical risk assessment in Europe	31
Ferroptosis as a mechanism of non-ferrous metal toxicity	31
ROS-associated immune response and metabolism: a mechanistic approach with implication of various diseases	30
Human variability in isoform-specific UDP-glucuronosyltransferases: markers of acute and chronic exposure, polymorphisms and uncertainty factors	30
Genetic toxicology and toxicokinetics of arecoline and related areca nut compounds: an updated review	30
Setting the stage for next-generation risk assessment with non-animal approaches: the EU-ToxRisk project experience	30
Acute effects of the imidacloprid metabolite desnitro-imidacloprid on human nACh receptors relevant for neuronal signaling	30
Dermal exposure to the UV filter benzophenone-3 during early pregnancy affects fetal growth and sex ratio of the progeny in mice	30
Lung injury induced by pyrrolizidine alkaloids depends on metabolism by hepatic cytochrome P450s and blood transport of reactive metabolites	29
The food contaminant, deoxynivalenol, modulates the Thelper/Treg balance and increases inflammatory bowel diseases	29
Neurotoxicity and underlying cellular changes of 21 mitochondrial respiratory chain inhibitors	29
In vitro human cell-based TTR-TRβ CALUX assay indicates thyroid hormone transport disruption of short-chain, medium-chain, and long-chain chlorinated paraffins	29
Ochratoxin A induces nephrotoxicity in vitro and in vivo via pyroptosis	29
Fumonisin B1 alters global m6A RNA methylation and epigenetically regulates Keap1-Nrf2 signaling in human hepatoma (HepG2) cells	28
Cancer potencies and margin of exposure used for comparative risk assessment of heated tobacco products and electronic cigarettes aerosols with cigarette smoke	28
The role of endogenous versus exogenous sources in the exposome of putative genotoxins and consequences for risk assessment	28
Kupffer cells regulate liver recovery through induction of chemokine receptor CXCR2 on hepatocytes after acetaminophen overdose in mice	28
Nrf2: a main responsive element in cells to mycotoxin-induced toxicity	28
Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis	27

Neonicotinoids: mechanisms of systemic toxicity based on oxidative stress-mitochondrial damage	27
The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods	26
Copper-dependent biological effects of particulate matter produced by brake systems on lung alveolar cells	26
Harnessing the power of novel animal-free test methods for the development of COVID-19 drugs and vaccines	26
Design and evaluation of bi-functional iron chelators for protection of dopaminergic neurons from toxicants	26
Health effects after inhalation of micro- and nano-sized zinc oxide particles in human volunteers	26
Estimation of health risks associated with dietary cadmium exposure	25
Metabolomic analysis to discriminate drug-induced liver injury (DILI) phenotypes	25
Dynamic alteration in miRNA and mRNA expression profiles at different stages of chronic arsenic exposure-induced carcinogenesis in a human cell culture model of skin cancer	25
Sirtuins as molecular targets, mediators, and protective agents in metal-induced toxicity	25
Hepatotoxic pyrrolizidine alkaloids induce DNA damage response in rat liver in a 28-day feeding study	25
Putative adverse outcome pathways for female reproductive disorders to improve testing and regulation of chemicals	24
Hepatotoxicity induced by nanomaterials: mechanisms and in vitro models	24
Cytochrome P450 expression, induction and activity in human induced pluripotent stem cell-derived intestinal organoids and comparison with primary human intestinal epithelial cells and Caco-2 cells	24
The beneficial effects of reducing NLRP3 inflammasome activation in the cardiotoxicity and the anti-cancer effects of doxorubicin	23
Acetylcholinesterase inhibition in electric eel and human donor blood: an in vitro approach to investigate interspecies differences and human variability in toxicodynamics	23
The “EU chemicals strategy for sustainability” questions regulatory toxicology as we know it: is it all rooted in sound scientific evidence?	23
N6-methyladenosine reader YTHDC2 and eraser FTO may determine hepatocellular carcinoma prognoses after transarterial chemoembolization	23
Cytochrome P450-dependent biotransformation capacities in embryonic, juvenile and adult stages of zebrafish (Danio rerio)—a state-of-the-art review	23
Implementing organ-on-chip in a next-generation risk assessment of chemicals: a review	23
Metabolism and interactions of Ivermectin with human cytochrome P450 enzymes and drug transporters, possible adverse and toxic effects	23
Pharmacology and toxicology of tannins	23
Toxicology and pharmacology of botulinum and tetanus neurotoxins: an update	23
Pharmacological evaluation and forensic case series of N-pyrrolidino etonitazene (etonitazepyne), a newly emerging 2-benzylbenzimidazole ‘nitazene’ synthetic opioid	23
Electronic cigarette aerosols induce oxidative stress-dependent cell death and NF-κB mediated acute lung inflammation in mice	22
Construction of pioneering quantitative structure activity relationship screening models for abuse potential of designer drugs using index of ideality of correlation in monte carlo optimization	22
In vitro structure–activity relationship determination of 30 psychedelic new psychoactive substances by means of β-arrestin 2 recruitment to the serotonin 2A receptor	22
Microsatellite instability in cancer: a novel landscape for diagnostic and therapeutic approach	22
Targeting organophosphorus compounds poisoning by novel quinuclidine-3 oximes: development of butyrylcholinesterase-based bioscavengers	22
Mutagenicity of acrylamide and glycidamide in human TP53 knock-in (Hupki) mouse embryo fibroblasts	22
Effects of the food colorant carmoisine on zebrafish embryos at a wide range of concentrations	22
Can seafood from marine sites of dumped World War relicts be eaten?	22
Pharmacology and toxicology of eteplirsen and SRP-5051 for DMD exon 51 skipping: an update	22
Clinical application of pyrrole–hemoglobin adducts as a biomarker of pyrrolizidine alkaloid exposure in humans	22
Chronic intestinal inflammation drives colorectal tumor formation triggered by dietary heme iron in vivo	21
Human metabolism and urinary excretion of seven neonicotinoids and neonicotinoid-like compounds after controlled oral dosages	21
Occupational endotoxin exposure and health effects	21
Delayed administration of N-acetylcysteine blunts recovery after an acetaminophen overdose unlike 4-methylpyrazole	21
Structure-dependent genotoxic potencies of selected pyrrolizidine alkaloids in metabolically competent HepG2 cells	20
A novel human pluripotent stem cell-based assay to predict developmental toxicity	20
New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids	20
Neurotoxicity evoked by organophosphates and available countermeasures	20
A review of species differences in the control of, and response to, chemical-induced thyroid hormone perturbations leading to thyroid cancer	20
Diagnosing intake and rationalizing toxicities associated with 5F-MDMB-PINACA and 4F-MDMB-BINACA abuse	20
Ochratoxin A induces epithelial-to-mesenchymal transition and renal fibrosis through TGF-β/Smad2/3 and Wnt1/β-catenin signaling pathways in vitro and in vivo	20
Toxicity of anticancer drugs in human placental tissue explants and trophoblast cell lines	19
Sacubitril/valsartan reduces endoplasmic reticulum stress in a rat model of doxorubicin-induced cardiotoxicity	19
Cytotoxicity of fractured quartz on THP-1 human macrophages: role of the membranolytic activity of quartz and phagolysosome destabilization	19
Benzo[a]pyrene and Caenorhabditis elegans: defining the genotoxic potential in an organism lacking the classical CYP1A1 pathway	19
Recent progress of iPSC technology in cardiac diseases	19
DMSO-free highly differentiated HepaRG spheroids for chronic toxicity, liver functions and genotoxicity studies	18
More than additive effects on liver triglyceride accumulation by combinations of steatotic and non-steatotic pesticides in HepaRG cells	18
Mechanisms of opioid-induced respiratory depression	18
Nephrotoxic antisense oligonucleotide SPC5001 induces kidney injury biomarkers in a proximal tubule-on-a-chip	18
Validation of the in vitro comet assay for DNA cross-links and altered bases detection	18
Effect of cryopreservation on DNA damage and DNA repair activity in human blood samples in the comet assay	18
Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates	18
E-vapor aerosols do not compromise bone integrity relative to cigarette smoke after 6-month inhalation in an ApoE–/– mouse model	17
Polyphenols: a route from bioavailability to bioactivity addressing potential health benefits to tackle human chronic diseases	17
Genetic variants in N6-methyladenosine are associated with bladder cancer risk in the Chinese population	17
Neurotoxic effects in zebrafish embryos by valproic acid and nine of its analogues: the fish-mouse connection?	17
Diversity of compounds in Vespa spp. venom and the epidemiology of its sting: a global appraisal	17
Glyphosate exposure induces synaptic impairment in hippocampal neurons and cognitive deficits in developing rats	17
Identification of genetic variants in m6A modification genes associated with pancreatic cancer risk in the Chinese population	17
Genetic variants in m6A regulators are associated with gastric cancer risk	17
A novel regQTL-SNP and the risk of lung cancer: a multi-dimensional study	17
Integrating in vitro data and physiologically based kinetic modeling-facilitated reverse dosimetry to predict human cardiotoxicity of methadone	17
Principles of dose-setting in toxicology studies: the importance of kinetics for ensuring human safety	16
The explosive trinitrotoluene (TNT) induces gene expression of carbonyl reductase in the blue mussel (Mytilus spp.): a new promising biomarker for sea dumped war relicts?	16
Replacement of animal testing by integrated approaches to testing and assessment (IATA): a call for in vivitrosi	16
The pro-radical hydrogen peroxide as a stable hydroxyl radical distributor: lessons from pancreatic beta cells	16
Development and safety of PI3K inhibitors in cancer	16
Human neuronal signaling and communication assays to assess functional neurotoxicity	16
The application of cytokeratin-18 as a biomarker for drug-induced liver injury	16
Cardiotoxicity of cyclophosphamide’s metabolites: an in vitro metabolomics approach in AC16 human cardiomyocytes	16
In vitro study of carbon black nanoparticles on human pulmonary artery endothelial cells: effects on calcium signaling and mitochondrial alterations	16
Roles of selected non-P450 human oxidoreductase enzymes in protective and toxic effects of chemicals: review and compilation of reactions	16
Synergistic effects of Bcl-2 inhibitors with AZD9291 on overcoming the acquired resistance of AZD9291 in H1975 cells	15
Epigenetic effects of low-level sodium arsenite exposure on human liver HepaRG cells	15
Use of in vitro bone models to screen for altered bone metabolism, osteopathies, and fracture healing: challenges of complex models	15

A workflow to build PBTK models for novel species	15
Triphenyl phosphate is a selective PPARγ modulator that does not induce brite adipogenesis in vitro and in vivo	15
Dapagliflozin protects against doxorubicin-induced cardiotoxicity by restoring STAT3	15
A review of cardiovascular effects and underlying mechanisms of legacy and emerging per- and polyfluoroalkyl substances (PFAS)	15
Subcellular spatio-temporal intravital kinetics of aflatoxin B1 and ochratoxin A in liver and kidney	15
Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application	15
A current perspective on snake venom composition and constituent protein families	15
In vitro biotransformation of pyrrolizidine alkaloids in different species: part II—identification and quantitative assessment of the metabolite profile of six structurally different pyrrolizidine alk	15
The role of hepatic cytochrome P450s in the cytotoxicity of sertraline	15
Integration of data across toxicity endpoints for improved safety assessment of chemicals: the example of carcinogenicity assessment	15
Brain alterations in GABA, glutamate and glutamine markers after chronic atrazine exposure in the male albino rat	15
The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment	15
Mechanistic perspectives on differential mitochondrial-based neuroprotective effects of several carnitine forms in Alzheimer’s disease in vitro model	15
Following the adverse outcome pathway from micronucleus to cancer using H2B-eGFP transgenic healthy stem cells	15
Shedding new light on early sex determination in zebrafish	15
A review and assessment of cyanobacterial toxins as cardiovascular health hazards	15
DNA methyltransferase- and histone deacetylase-mediated epigenetic alterations induced by low-level methylmercury exposure disrupt neuronal development	15
Dose-dependent pleiotropic role of neutrophils during acetaminophen-induced liver injury in male and female mice	15
Autophagy: a promising process for the treatment of acetaminophen-induced liver injury	15
Deoxynivalenol induces caspase-3/GSDME-dependent pyroptosis and inflammation in mouse liver and HepaRG cells	15
In vitro function and in situ localization of Multidrug Resistance-associated Protein (MRP)1 (ABCC1) suggest a protective role against methyl mercury-induced oxidative stress in the human placenta	15
Carbon monoxide-triggered health effects: the important role of the inflammasome and its possible crosstalk with autophagy and exosomes	15
An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury	15
Compulsive methamphetamine taking induces autophagic and apoptotic markers in the rat dorsal striatum	14
Expanded high-throughput screening and chemotype-enrichment analysis of the phase II: e1k ToxCast library for human sodium-iodide symporter (NIS) inhibition	14
Inter-laboratory automation of the in vitro micronucleus assay using imaging flow cytometry and deep learning	14
Systems analysis of miRNA biomarkers to inform drug safety	14
Intestinal and hepatic effects of iron oxide nanoparticles	14
Mapping DEHP to the adverse outcome pathway network for human female reproductive toxicity	14
Ingestion of titanium dioxide nanoparticles: a definite health risk for consumers and their progeny	14
Recent research on Novichok	14
Infections at the nexus of metabolic-associated fatty liver disease	14
Gut microbiota and undigested food constituents modify toxin composition and suppress the genotoxicity of a naturally occurring mixture of Alternaria toxins in vitro	14
Impaired protein adduct removal following repeat administration of subtoxic doses of acetaminophen enhances liver injury in fed mice	14
CYP-associated drug–drug interactions: A mission accomplished?	14
Electronic cigarette vapour moderately stimulates pro-inflammatory signalling pathways and interleukin-6 production by human monocyte-derived dendritic cells	14
Fluorescent tagging of endogenous Heme oxygenase-1 in human induced pluripotent stem cells for high content imaging of oxidative stress in various differentiated lineages	14
Identification and characterization of potent, selective, and efficacious inhibitors of human arylamine N-acetyltransferase 1	14
The diarrhetic shellfish-poisoning toxin, okadaic acid, provokes gastropathy, dysbiosis and susceptibility to bacterial infection in a non-rodent bioassay, Galleria mellonella	14
Toll of acute methanol poisoning for preventing COVID-19	13
Human metabolism and kinetics of the UV absorber 2-(2H-benzotriazol-2-yl)-4,6-di-tert-pentylphenol (UV 328) after oral administration	13
Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model	13
Monocrotaline-induced liver toxicity in rat predicted by a combined in vitro physiologically based kinetic modeling approach	13
Cannabidiol disrupts apoptosis, autophagy and invasion processes of placental trophoblasts	13
Detection of genome-wide low-frequency mutations with Paired-End and Complementary Consensus Sequencing (PECC-Seq) revealed end-repair-derived artifacts as residual errors	13
Evaluation of toxicity of aerosols from flavored e-liquids in Sprague–Dawley rats in a 90-day OECD inhalation study, complemented by transcriptomics analysis	13
Inhibition of neurite outgrowth and enhanced effects compared to baseline toxicity in SH-SY5Y cells	13
Cell survival after DNA damage in the comet assay	13
Effects of co-formulants on the absorption and secretion of active substances in plant protection products in vitro	13
Developments in high-resolution mass spectrometric analyses of new psychoactive substances	13
Differences in P-glycoprotein activity in human and rodent blood–brain barrier assessed by mechanistic modelling	13
Role of Ca2+ in healthy and pathologic cardiac function: from normal excitation–contraction coupling to mutations that cause inherited arrhythmia	13
First identification, chemical analysis and pharmacological characterization of N-piperidinyl etonitazene (etonitazepipne), a recent addition to the 2-benzylbenzimidazole opioid subclass	13
Ensemble machine learning to evaluate the in vivo acute oral toxicity and in vitro human acetylcholinesterase inhibitory activity of organophosphates	13
Immunomodulation and exposure to per- and polyfluoroalkyl substances: an overview of the current evidence from animal and human studies	13
Effect of methylmercury on fetal neurobehavioral development: an overview of the possible mechanisms of toxicity and the neuroprotective effect of phytochemicals	13
Bothrops lanceolatus snake (Fer-de-lance) venom triggers inflammatory mediators’ storm in human blood	12
Microbially competent 3D skin: a test system that reveals insight into host–microbe interactions and their potential toxicological impact	12
Intrauterine RAS programming alteration-mediated susceptibility and heritability of temporal lobe epilepsy in male offspring rats induced by prenatal dexamethasone exposure	12
A comparison of thyroidal protection by stable iodine or perchlorate in the case of acute or prolonged radioiodine exposure	12
Acute exposure to microcystin-LR induces hepatopancreas toxicity in the Chinese mitten crab (Eriocheir sinensis)	12
Treatments of a phthalocyanine-based green ink for tattoo removal purposes: generation of toxic fragments and potentially harmful morphologies	12
Contribution to the ongoing discussion on fluoride toxicity	12
A human stem cell-derived test system for agents modifying neuronal N-methyl-d-aspartate-type glutamate receptor Ca2+-signalling	12
The BH3 mimetic (±) gossypol induces ROS-independent apoptosis and mitochondrial dysfunction in human A375 melanoma cells in vitro	12
Long-term fate of etoposide-induced micronuclei and micronucleated cells in Hela-H2B-GFP cells	12
Autophagy alleviates amiodarone-induced hepatotoxicity	12
Effect of common medications on the expression of SARS-CoV-2 entry receptors in liver tissue	12
A mixture of chloromethylisothiazolinone and methylisothiazolinone impairs rat vascular smooth muscle by depleting thiols and thereby elevating cytosolic Zn2+ and generating reactive oxygen species	12
Clioquinol inhibits dopamine-β-hydroxylase secretion and noradrenaline synthesis by affecting the redox status of ATOX1 and copper transport in human neuroblastoma SH-SY5Y cells	12
Functional genetic variants in centrosome-related genes CEP72 and YWHAG confer susceptibility to gastric cancer	12
Impacts of bisphosphonates on the bone and its surrounding tissues: mechanistic insights into medication-related osteonecrosis of the jaw	12
The electrophysiological effects of cannabidiol on action potentials and transmembrane potassium currents in rabbit and dog cardiac ventricular preparations	12
Formaldehyde-induced hematopoietic stem and progenitor cell toxicity in mouse lung and nose	12
Tissue-specific Nrf2 signaling protects against methylmercury toxicity in Drosophila neuromuscular development	12
Exploring the dermotoxicity of the mycotoxin deoxynivalenol: combined morphologic and proteomic profiling of human epidermal cells reveals alteration of lipid biosynthesis machinery and membrane struc	11
Quo vadis blood protein adductomics?	11
In vitro interactions of Alternaria mycotoxins, an emerging class of food contaminants, with the gut microbiota: a bidirectional relationship	11
Constitutive androstane receptor (CAR) mediates dieldrin-induced liver tumorigenesis in mouse	11
Activation of autophagy triggers mitochondrial loss and changes acetylation profile relevant for mechanotransduction in bladder cancer cells	11
Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A	11
In silico, in vitro, and in vivo human metabolism of acetazolamide, a carbonic anhydrase inhibitor and common “diuretic and masking agent” in doping	11
Ascorbate: antioxidant and biochemical activities and their importance for in vitro models	11
Hypersensitivity of bladder low threshold, wide dynamic range, afferent fibres following treatment with the chemotherapeutic drugs cyclophosphamide and ifosfamide	11
Circular RNA circ_Cabin1 promotes DNA damage in multiple mouse organs via inhibition of non-homologous end-joining repair upon PM2.5 exposure	11
Metabolic profiling as a powerful tool for the analysis of cellular alterations caused by 20 mycotoxins in HepG2 cells	11
The potential of remdesivir to affect function, metabolism and proliferation of cardiac and kidney cells in vitro	11
Farnesoid X receptor (FXR) agonists induce hepatocellular apoptosis and impair hepatic functions via FXR/SHP pathway	11
Understanding the molecular mechanisms of statin pleiotropic effects	11
In vitro assessment of the photo(geno)toxicity associated with Lapatinib, a Tyrosine Kinase inhibitor	11
Yttrium chloride-induced cytotoxicity and DNA damage response via ROS generation and inhibition of Nrf2/PPARγ pathways in H9c2 cardiomyocytes	11
In vitro effects of the endocrine disruptor p,p′DDT on human choriogonadotropin/luteinizing hormone receptor signalling	11
Nanoparticle-induced inflammation and fibrosis in ex vivo murine precision-cut liver slices and effects of nanoparticle exposure conditions	11
Pharmacokinetics and toxicity evaluation following oral exposure to bisphenol F	11
Spatiotemporal analysis of the UPR transition induced by methylmercury in the mouse brain	11