Intensive Care Medicine

Article	Citations
Obituary and tribute to Professor J. Randall Curtis (Randy)	2833
Variation in intensive care unit beds capacity in China from 2007 to 2021	480
Effect of proning and recruitment on physio-anatomical variables in COVID-19 pneumonia	320
The effects of pantoprazole vs. placebo on 1-year outcomes, resource use and employment status in ICU patients at risk for gastrointestinal bleeding: a secondary analysis of the SUP-ICU trial	250
Time course of physiological variables during inter-hospital helicopter transport of ventilated COVID-19 patients	184
Basic ultrasound skill for intensivists: future scope for expansion of the recommendations of the European Society of Intensive Care Medicine	172
Full enteral nutrition should be avoided among patients with high vasopressor dose and low flow state	150
Close collaboration between pathologists and intensivists to understand (not just) coronavirus disease	149
The certainty of parental love vs. the uncertainty of a “best” decision	148
Optimal oxygen and mean arterial blood pressure targets after cardiac arrest	145
Pitfalls in the use of microcirculation as a resuscitation goal	131
Influenza and prophylactic antifungal therapy for aspergillosis: addressing some questions first	130
Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis	128
Weaning strategy in patients at low-to-medium risk of extubation failure	128
Workplace equity for clinicians with a disability: why it matters for all	125
Major adverse kidney events as an endpoint in acute kidney injury trials: is it time for a RE-MAKE?	113
Severe Pneumocystis jirovecii pneumonia: time to reassess our practices	113
Personalized oxygen targets are needed for extracorporeal membrane oxygenation	111
Preventing stress ulcer bleeding	107
No ventilation, no ARDS: insights from four-dimensional computed tomography as dynamic imaging	97
Quantifying benefit and harm of extracorporeal life support in cardiogenic shock complicating acute myocardial infarction	93
Correction to: Noninvasive respiratory support in intensive care medicine	92
Nicotine patches in patients on mechanical ventilation for severe COVID-19: a randomized, double-blind, placebo-controlled, multicentre trial	90
Lung-protective sedation: moving toward a new paradigm of precision sedation	87
Comparing intravascular and surface cooling methods: a critical look at outcomes for out-of-hospital cardiac arrest patients—author's reply	85

Measuring patient’s effort on the ventilator	85
A double plea for dyspnea as the next great cause of all ICU professions and for caution about the dyspnea-breathlessness equivalence	84
Frailty in intensive care medicine must be measured, interpreted and taken into account!	83
Beyond inflammation: the role of metabolic dysregulation in sepsis diagnosis and treatment	81
Staircase strategy, tier-three therapies, and effects on outcome in traumatic brain injured patients: the Triple-T TBI study	80
The 5-year pre- and post-hospitalization treated prevalence of mental disorders and psychotropic medication use in critically ill patients: a Canadian population-based study	79
Correction: Expanding the role of PoCUS in tailoring diuretic strategies for congestion management in critical care	77
Greenery and outdoor facilities to improve the wellbeing of critically ill patients, their families and caregivers: things to consider	77
Anesthetic drugs for rapid sequence intubation: ketamine, but what dose?	75
Left ventricular diastolic dysfunction is prevalent but not associated with mortality in patients with septic shock	75
18F-fluorodeoxyglucose positron emission tomography/computed tomography differentiates between pneumonia and atelectasis in a mechanically ventilated patient	75
SHAP model explainability in ECMO–PAL mortality prediction: a critical analysis	74
Persistent signs of poisoning after massive drug ingestion: move the ultrasound probe to the stomach	74
Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions	73
Using the helmet	73
Mental health sequelae in survivors of cardiogenic shock complicating myocardial infarction. A population-based cohort study	72
Norepinephrine dose and concentration reporting: a closer look at the fine print	70
Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial	70
Sequencing interventions in ARDS: the critical role of timing and order in standardized management	68
Dose of norepinephrine: the devil is in the details	67
Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia	65
Exposure to ambient air pollutants and acute respiratory distress syndrome risk in sepsis	63
Age and associated outcomes among patients receiving venovenous extracorporeal membrane oxygenation for acute respiratory failure: analysis of the Extracorporeal Life Support Organization registry	63
Targeted temperature management following out-of-hospital cardiac arrest: a systematic review and network meta-analysis of temperature targets	62
Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury	62
Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients (FORECAST): a prospective, multi-centre, cohort study	61
Effects of small volume resuscitation with hypertonic saline on body water distribution in ICU patients after cardiac surgery	61
Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis	61
Status epilepticus in the ICU	61
Ten myths about Albumin: don’t forget the endothelium. Author’s reply	59
Role of PEEP on the prognostic performance of the ROX index in hypoxemic respiratory failure due to COVID-19: any further gain in outcome prediction?	59
Dichotomy between ventilator associated-pneumonia/tracheobronchitis: did you ask the lung its opinion? Author's reply	57
Relationship of multidrug-resistant bacterial colonization and immune status of patients in the ICU	57
Rapid temperature increases under isoflurane sedation	54
Central venous pressure not appropriate to guide volume administration in patients with high-risk pulmonary embolism	54
Correction: Determinants of fluid use and the association between volume of fluid used and effect of balanced solutions on mortality in critically ill patients: a secondary analysis of the BaSICS tria	53
Securing the airway in critical care scenarios: questioning the fundamentals	53
NeuroWatch in acute respiratory distress syndrome: time to tune strategies	52
The role of pleural pressure and airway closure during mechanical ventilation. Author's reply	52
Towards evidence-based staffing: the promise and pitfalls of patient-to-intensivist ratios	52
Bone marrow necrosis induced by massive Staphylococcus aureus infiltration	49
The challenge of pharmacological thromboprophylaxis in ICU patients: anti-FXa activity does not constitute a simple solution	49
A call to measure family presence in the adult intensive care unit	49
Moderate hypocapnia for intracranial pressure control after traumatic brain injury: a common practice requiring further investigations	48
Should we move beyond the concept of fluid responsiveness?	48
Frailty is crucial in FORECASTing outcomes in critical care	47
“Fake” or real hypoxia?: A brainy dilemma	46
A common longitudinal intensive care unit data format (CLIF) for critical illness research	45
Paradoxical carbon dioxide embolism during laparoscopic nephrectomy	45
Introduction to an intensive care recycling program	44

Fly me to the moon	44
Visco-elastic testing in traumatic bleeding	44
Retraction Note: Influence of nimodipine and nifedipine on intrapulmonary shunting – a comparison to other vasoactive drugs	44
What’s new in intensive care: disease tolerance	42
B-ICONIC vs. Reality: The Feasibility Gap in Neuro-Ultrasound Recommendations and Achievability. Authors’ reply	41
Humanizing Delirium Care	41
Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults	41
Management of diabetic ketoacidosis	41
Less is more. Atmospheric and environmental stakes - sedate with care	41
Sepsis subphenotypes, theragnostics and personalized sepsis care	41
Ten myths about albumin	40
How can assessing hemodynamics help to assess volume status?	40
Correction: Association of hospital and intensive care unit occupancy and non-admission to the intensive care unit decisions: a retrospective cohort study	40
Double sequential external defibrillation for refractory ventricular fibrillation	40
Metabolic septic shock sub-phenotypes, stability over time and association with clinical outcome	40
Treatment of positive catheter tip culture without bloodstream infections in critically ill patients. A case-cohort study from the OUTCOMEREA network	39
The role of pleural pressure on fluid dynamics and responsiveness	39
Left atrial reservoir strain: an essential tool for evaluating left ventricular diastolic dysfunction in 2025	39
Microcirculation information in clinical decision making: Rome wasn't built in a day	39
Correction: ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia	37
Head-to-toe bedside ultrasound for adult patients on extracorporeal membrane oxygenation	37
Consumptive coagulopathy: how low-dose unfractionated heparin can prevent bleeding complications during extracorporeal life support	37
Ten reasons for the presence of pharmacy professionals in the intensive care unit	37
Drugs for advanced life support	36
Long-term survival comparison of patients admitted to the intensive care unit following in-hospital cardiac arrest in perioperative and ward settings. A multicentre retrospective cohort study	36
Anesthetic drugs for rapid sequence intubation: ketamine, but what dose? Author’s reply	36
Melatonin for prevention of delirium in patients receiving mechanical ventilation in the intensive care unit: a multiarm multistage adaptive randomized controlled clinical trial (DEMEL)	36
Long-term outcomes of intensive care unit delirium	36
Sweeping TTM conclusion may deprive many post-arrest patients of effective therapy. Author’s reply	35
What really matters with thrombocytopenia: absolute value, timing, etiology or management? Author's reply	35
Correction to: Palliative care interventions in intensive care unit patients	34
Caring for the dying patient in ICU	34
The weighing	34
Intensive Care admission aiming at organ donation as a duty of the intensivist: every organ, every time	34
Multiple intracardiac thrombi in a patient with extracorporeal membrane oxygenation	33
Optimising aerosolized therapies in critically ill patients	33
Effect of albumin bolus therapy on vasopressor requirement after cardiac surgery	33
Ten tips on sepsis-induced thrombocytopenia	32
Can the terms “low resource setting” and “low-income country” be used interchangeably in the context of intensive care medicine?	32
Building a better machine learning model of extubation for neurocritical care patients. Author’s reply	32
Selective digestive decontamination- Not sure	31
Noninvasive ventilation on reintubation in patients with obesity and hypoxemic respiratory failure following abdominal surgery: a post hoc analysis of a randomized clinical trial	31
Targeting inflammation in traumatic injury: entering a new era	31
Kidney replacement therapy in critically ill obese patients: an urgent call for precision and evidence-based practice!	31
Defining basic (lung) ultrasound skills; not so basic after all? Author’s reply	31
Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis	31
High versus low positive end-expiratory pressure during noninvasive ventilation for hypoxemic respiratory failure: balancing efficacy and lung protection—author’s reply	31
Reevaluating definitions and modifiable factors in persistent severe acute kidney injury	30
Awareness of dying: adjustments in family relationships at the end of life	30
Undocumented migrants in French intensive care units in 2011–2018: retrospective nationwide study	30
Renal replacement therapy initiation strategies in comatose patients with severe acute kidney injury: a secondary analysis of a multicenter randomized controlled trial	30
Lung and diaphragm protective ventilation guided by the esophageal pressure	30
Correspondence on "Using toxidromes in the ICU"	29
Penicillin allergy assessment and testing: worth the risk in critically ill patients	29
ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia	28
ECMO PAL: using deep neural networks for survival prediction in venoarterial extracorporeal membrane oxygenation	28
Effect of albumin bolus therapy on vasopressor requirement after cardiac surgery? Author’s reply	28
Bronchoscopy for diagnosis of ventilator-associated pneumonia	28
Ecological effects of selective oral decontamination on multidrug-resistance bacteria acquired in the intensive care unit: a case–control study over 5 years	28
Terlipressin use in HRS-AKI and respiratory failure	28
De-adoption of chlorhexidine oral care and ICU mortality. Authors’ reply	28
Tracheal intubation in critically ill adults with a physiologically difficult airway. An international Delphi study	28
Bronchoscopic examination of an invasive aspergillosis in acute myeloid leukemia	28
Plasma exchange in septic shock: are we ready for prime time? PRO	28
Critical insights into venoarterial extracorporeal membrane oxygenation outcomes in immunocompromised patients: addressing uncertainties in cause of death and treatment strategies. Author’s reply	28
Would my “Eriksen” wake up again?	27
Subphenotypes in critical illness: a priori biological rationale is key. Author’s reply	27
Bridging the gap: implementing ESICM end-of-life care guidelines in resource-limited settings	27
On acid-base bilingualism	27
Acute kidney injury	27
Integrating multidisciplinary expertise in postoperative noninvasive ventilation management. Authors’ reply	27
Delirium in ICU and Macbeth’s dagger: author’s reply	27
Reusable versus single-use ICU equipment: what’s the environmental footprint?	26
Hemoadsorption in septic shock – PRO	26
Unlocking consciousness through right median nerve stimulation. Has a potential cure arrived at our doorstep?	26
Understanding buffering of metabolic acidosis in critical illness	26
What intensivists need to know about cytomegalovirus infection in immunocompromised ICU patients	26
High and intermediate risk pulmonary embolism in the ICU	26
How to approach a patient hospitalized for pneumonia who is not responding to treatment?	25
Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM	25

Managing blood glucose control in the intensive care unit	25
AI in neurocritical care: what to expect	25
Caring for frail patients in the ICU: a multidimensional approach	25
Prognostic value of global deep white matter DTI metrics for 1-year outcome prediction in ICU traumatic brain injury patients: an MRI-COMA and CENTER-TBI combined study	24
Accuracy of continuous glucose monitoring systems in intensive care unit patients: a scoping review	24
Retraction Note: Phosphodiesterase-inhibitors enoximone and piroximone in cardiac surgery: influence on platelet count and function	24
Machines that help machines to help patients: optimising antimicrobial dosing in patients receiving extracorporeal membrane oxygenation and renal replacement therapy using dosing software	24
Absence of candidemia in critically ill patients with COVID-19 receiving selective digestive decontamination	23
Confusion regarding the use of Natural Language Processing in ICU delirium assessment. Author’s reply	23
Early ICU mobilisation predicting functional impairment at hospital discharge. Author's reply	23
My advice to the NEXT generation	23
Correction to: Survival benefit of extracorporeal membrane oxygenation in severe COVID-19: a multi-centre-matched cohort study	23
Analgesia as part of the orotracheal intubation induction sequence. Author's reply	22
How to optimize extubation?	22
Obituary and tribute to Professor Tobias Welte	22
Prevention of upper gastrointestinal bleeding in critical illness	22
Hyperoxia and traumatic brain injury: time to stop cooking the books?	22
We are proud of you Jamie	22
Massive gaseous embolism during cardiopulmonary resuscitation for massive hemoptysis in a COVID-19-associated pulmonary aspergillosis	22
Coronavirus disease 2019	22
Come hell or high water: climate change through the lens of neurocritical care	22
Preventing acute kidney injury and its longer-term impact in the critically ill	21
Characteristics of co-infection and secondary infection amongst critically ill COVID-19 patients in the first two waves of the pandemic	21
Sex representation within intensive care trials in Australia and New Zealand	21
Clinical governance in intensive care medicine	21
Monitoring cardiac output	21
Challenges for a broad international implementation of the current severe community-acquired pneumonia guidelines	21
Equity in patient care in the intensive care unit	21
Time-limited trial of intensive care is more than merely life sustaining	21
Human albumin solution for on-pump cardiac surgery: benefit or burden? Author’s reply	21
Effect of oral chlorhexidine de-adoption and implementation of an oral care bundle on mortality for mechanically ventilated patients in the intensive care unit (CHORAL): a multi-center stepped wedge c	21
Contemporary management of major haemorrhage in critical care	21
Comparison of 8 versus 15 days of antibiotic therapy for Pseudomonas aeruginosa ventilator-associated pneumonia in adults: a randomized, controlled, open-label trial	21
Incidence and risk factors of mental illness among the spouses of patients with sepsis: a population-based cohort study	21
Initiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial	20
Correction: Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU)	20
Correction: Variation in intensive care unit beds capacity in China from 2007 to 2021	20
Ketamine for emergency endotracheal intubation: insights into post-induction hemodynamic instability	20
The dawn of target trials in intensive care: time to move beyond association is not causation	20
C-reactive protein rise in response to macronutrient deficit early in critical illness: sign of inflammation or mediator of infection prevention and recovery	20
War, from the inside	20
Central venous pressure (CVP)	20
Using ultrasound in ICU	20
Heterogeneity in a meta-analysis: randomized controlled trials versus observational studies	20
Ceremonial purification: which rite is right in liver failure?	20
During the storm	20
Neuromonitoring for prognostication under ECMO	20
The paradox of post-intensive care unit physical therapy	19
The role of inferior vena cava in predicting fluid responsiveness	19
Human albumin solution for on-pump cardiac surgery: benefit or burden?	19
The next big epidemic? Device shutdowns	19
The relationship of malnutrition, frailty, and sarcopenia in critical care	19
Brave enough	19
Shorter might not always be better: the case for longer antibiotic therapy for Pseudomonas aeruginosa pneumonia	18
Driving pressure: pitfalls of methods that do not use esophageal pressure measurement	18
Respective roles of hypercapnia and acidosis in acute distress respiratory syndrome	18
Correction: Effect modification in a clinical trial should be assessed through interaction terms, not prognostic modelling	18
Increased risk of central line-associated bloodstream infection in COVID-19 patients associated with dexamethasone but not with interleukin antagonists	18
Air pollutant exposure and mortality risk of critically ill patients	18
Gymnopédie: music in the ICU	18
Correction: Influence of socio-economic status on functional recovery after ARDS caused by SARS-CoV-2: the multicentre, observational RECOVIDS study	18
Unraveling the enigma of genetics and phenotypes in ARDS	18
Retraction Note: Right ventricular function and cardiac surgery	17
COVID-19 associated pulmonary aspergillosis: regional variation in incidence and diagnostic challenges	17
Association between driving pressure and mortality may depend on timing since onset of acute respiratory distress syndrome	17
REMAP-CAP corticosteroids: yet, another swing of the pendulum?	17
Optimizing ICU antifungal therapy: overcoming pharmacokinetic limitations with combination strategies—author's reply	17
Pressure control plus spontaneous ventilation versus volume assist-control ventilation in acute respiratory distress syndrome. A randomised clinical trial	17
To mobilise or not to mobilise: is that the right question?	17
Correction: Direct assessment of microcirculation in shock: a randomized-controlled multicenter study	17
Bidirectional ventricular tachycardia, a very rare and severe complication of digoxin poisoning	17
Retraction Note: The new phosphodiesterase inhibitor enoximone in patients following cardiac surgery – pharmacokinetics and influence on parameters of coagulation	17
Using diuretic therapy in the critically ill patient	17
Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting	17
Validation of the “invasive pulmonary aspergillosis in immunocompromised patients with acute respiratory failure score” (IPA-GRRR-OH score)	17
Effect of aggressive vs conservative screening and confirmatory test on time to extubation among patients at low or intermediate risk: a randomized clinical trial	16
Shortening antibiotic therapy duration for hospital-acquired bloodstream infections in critically ill patients: a causal inference model from the international EUROBACT-2 database	16
The forgotten relevance of central venous pressure monitoring	16
Sex and gender differences in intensive care medicine	16
Persistent severe AKI is bad—where to go now?	16
Correction: ESICM consensus-based recommendations for the management of very old patients in intensive care	16
Recommendations for clinical trial design in acute kidney injury from the 31st acute disease quality initiative consensus conference. A consensus statement	16
The prediction of fluid responsiveness	16
Onco-nephrology: what the intensivist needs to know	16
Author Correction: Hemoadsorption in septic shock—CON	16
Clustering analysis of geriatric and acute characteristics in a cohort of very old patients on admission to ICU	16
Intensive care management of acute-on-chronic liver failure	16
Norepinephrine pharmacolexicology: a chronological review of dose reporting and the implications of salt formulations	16
Retraction Note: The effects of pentoxifylline on circulating adhesion molecules in critically ill patients with acute renal failure treated by continuous veno-venous hemofiltration	15
The TARGET trial as a plea for model-informed precision dosing of piperacillin/tazobactam in patients with sepsis	15
Prognostication model for traumatic brain injury based on age and white matter diffusion metrics in MRI brain. Author’s reply	15
Basic ultrasound skill for intensivists: future scope for expansion of the recommendations of the European Society of Intensive Care Medicine. Author's reply	15
Another trial for the TARGET trial. Author’s reply	15
Cardiac manifestations in critically ill patients with COVID-19: do we really know what hit us?	15
Where is the imperceptible difference?	14