Intensive Care Medicine

Papers
(The TQCC of Intensive Care Medicine is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Retraction Note: The effects of pentoxifylline on circulating adhesion molecules in critically ill patients with acute renal failure treated by continuous veno-venous hemofiltration2451
Retraction Note: Glycogen synthase kinase-3β inhibition attenuates the development of ischaemia/reperfusion injury of the gut385
Retraction Note: Influence of different volume therapies on platelet function in the critically ill271
Correction: Expanding the role of PoCUS in tailoring diuretic strategies for congestion management in critical care266
An unusual case of hypoxic-ischemic brain injury related to reversible cerebral vasoconstriction syndrome203
Effectiveness of bundle of care on tolerance of awake-prone positioning in patients with acute respiratory failure. A multicenter observational study202
Ventilator induced lung injury: a case for a larger umbrella?171
What language conveys distress and reassurance?167
Critical care ultrasound goal-directed versus early goal-directed therapy in septic shock156
Left ventricular diastolic dysfunction is prevalent but not associated with mortality in patients with septic shock139
Utilization and outcomes of life-supporting interventions in older ICU patients in Japan: a nationwide registry study135
Sepsis subtypes and differential treatment response to vitamin C: biological sub-study of the LOVIT trial130
Higher mortality in female versus male critically ill patients at comparable thresholds of mechanical power: necessity of normalization to functional lung size127
Obituary and tribute to Professor J. Randall Curtis (Randy)121
Staying optimistic in the face of war121
Mental health sequelae in survivors of cardiogenic shock complicating myocardial infarction. A population-based cohort study119
Dexmedetomidine vs other sedatives in critically ill mechanically ventilated adults: a systematic review and meta-analysis of randomized trials118
Validation of pre-conditioning EASIX for prediction of sepsis after allogeneic stem cell transplantation113
A checklist for environmentally responsible research within the ICU108
Understanding buffering of metabolic acidosis in critically ill: keep an open mind106
Spontaneous pulmonary-twist secondary to Legionnaire’s disease103
Influence of socio-economic status on functional recovery after ARDS caused by SARS-CoV-2: the multicentre, observational RECOVIDS study103
Variation in intensive care unit beds capacity in China from 2007 to 2021103
Hemodynamic impact of prone position. Let’s protect the lung and its circulation to improve prognosis97
Epidemiology, clinical presentation, and outcomes of 620 patients with eosinophilia in the intensive care unit90
Empirical antimicrobials in the intensive care unit81
Falsifiability in medicine: what clinicians can learn from Karl Popper77
Virtual reality in intensive care77
Thromboprophylaxis in critical care76
Comparison of radiographic pneumothorax and pneumomediastinum in COVID-19 vs. non-COVID-19 acute respiratory distress syndrome76
Decision-making process during limitation life-sustaining support meetings in French intensive care units75
Introducing an external team for ICU family communication during the pandemic: not without risks74
Visitation policies in the ICU and the importance of family presence at the bedside73
Before AKI, renal microcirculation stress may be detected by urine biochemistry. Author’s reply72
Personalized medicine in COVID-1972
Close collaboration between pathologists and intensivists to understand (not just) coronavirus disease71
ROX index to predict CPAP outcome in hypoxemic respiratory failure due to COVID-1971
The Janus face of oxygen in traumatic brain injury70
Lung-protective sedation: moving toward a new paradigm of precision sedation70
Decontamination regimens: do not forget half of the protocol. Author's reply68
Etomidate for endotracheal intubation in sepsis67
Intracranial pressure monitoring devices compatibility with magnetic resonance imaging66
Correction: Intracranial pressure: current perspectives on physiology and monitoring66
Real-time 4D transesophageal echocardiography in the evaluation of cardioaortic embolism: the value of completing a comprehensive protocol65
Acute respiratory failure from an obstructive fibrinous tracheal pseudomembrane64
The cytokine adsorber Cytosorb® does not reduce ammonia concentrations in critically ill patients with liver failure64
Correction: High arterial oxygen levels and supplemental oxygen administration in traumatic brain injury: insights from CENTER-TBI and OzENTER-TBI64
The effect of vasopressin and hydrocortisone on cytokine trajectories64
Correction: Impact of renal-replacement therapy strategies on outcomes for patients with chronic kidney disease: a secondary analysis of the STARRT-AKI trial62
Correction: Partition of respiratory mechanics in patients with acute respiratory distress syndrome and association with outcome: a multicentre clinical study62
Evolution of purpura fulminans61
Artificially intelligent reflection? Smoke and mirrors and a tale of two perspectives60
Excess mortality among non-COVID-19 surgical patients attributable to the exposure of French intensive and intermediate care units to the pandemic60
The certainty of parental love vs. the uncertainty of a “best” decision59
Ten tips on fever56
Liver transplantation for patients with severe acute on chronic liver failure: it is time to change paradigms55
Ten tips to manage severe acute pancreatitis in an intensive care unit55
COVID-19-associated pulmonary aspergillosis (CAPA) might be associated with increased risk for pneumopleural fistula55
Renal function in the ICU: always look both ways before initiating venous thromboprophylaxis55
Optimal oxygen and mean arterial blood pressure targets after cardiac arrest55
Prehospital ventilation targets in severe traumatic brain injury55
Exposure to ambient air pollutants and acute respiratory distress syndrome risk in sepsis54
Pitfalls in the use of microcirculation as a resuscitation goal53
What should a “surviving severe ACLF campaign” look like?52
Resistance to unfractionated heparin in the ICU: evaluation and management options52
Organ donation after circulatory death: please avoid undue haste!51
Machine learning to predict poor school performance in paediatric survivors of intensive care: a population-based cohort study51
Paediatric intensive care challenges caused by indirect effects of the COVID-19 pandemic50
Dichotomy between ventilator-associated pneumonia/-tracheobronchitis: did you ask the lung its opinion?50
Intra-cycle power: is the flow profile a neglected component of lung protection?50
Diversity and inclusivity: the way to multidisciplinary intensive care medicine in Europe49
Fentanyl- and midazolam-induced coma each influence days of mechanical ventilation and 28-day mortality47
Effectiveness of blue light-emitting glasses for intensive care unit health care workers on night shifts during the COVID-19 pandemic47
Tackling sepsis-associated acute kidney injury using routinely collected data47
If not now, when? A clinical perspective on the unprecedented challenges facing ICUs during the COVID-19 pandemic46
What's new with glucocorticoids in severe community-acquired pneumonia?46
Double the risk of death and other ‘inconvenient truths’ about oliguria. Author's reply46
No blood transfusion for my own anaemia—tit for tat?46
Microcirculation as a guide for therapy: do not condemn an innocent without a fair trial45
Correction: Feasibility of conservative fluid administration and deresuscitation compared with usual care in critical illness: the Role of Active Deresuscitation Correction: After Resuscitation-2 (RAD44
Post-hospital recovery trajectories of family members of critically ill COVID-19 survivors: an international qualitative investigation44
Probiotic therapy in critical illness: does it hold water?44
COVID-19-associated autoimmunity as a feature of acute respiratory failure44
Tocilizumab in COVID-19: a meta-analysis, trial sequential analysis, and meta-regression of randomized-controlled trials42
High-flow oxygen during spontaneous breathing trial for patients at high risk of weaning failure41
Racial and ethnic minority participants in clinical trials of acute respiratory distress syndrome41
Back to the future: ARDS guidelines, evidence, and opinions41
Use of stylet and airway management procedure in critically ill patients40
When could airway plateau pressure above 30 cmH2O be acceptable in ARDS patients?40
Decidual stromal cells for the treatment of severe COVID-19 ARDS40
Influenza and prophylactic antifungal therapy for aspergillosis: addressing some questions first39
Harlequin syndrome after surgery for aortic dissection39
SHAP model explainability in ECMO–PAL mortality prediction: a critical analysis39
Hope will never be silent: standing tall with the LGBTQ + community39
Venous thromboembolism in critically ill adult patients with hematologic malignancy: a population-based cohort study38
The 5-year pre- and post-hospitalization treated prevalence of mental disorders and psychotropic medication use in critically ill patients: a Canadian population-based study37
Face-to-face courses: the environmental considerations for centralised vs local approaches using a free, open-access, online carbon cost calculator37
The pathophysiology of anaphylactic shock captured on computed tomography images36
De senectute and the art of medicine: how old is too old for ECMO in cardiogenic shock?35
Behavioural artificial intelligence technology for COVID-19 intensivist triage decisions: making the implicit explicit35
Management of supraventricular arrhythmias in the intensive care unit: a step in the right direction35
Fluid management in diabetic ketoacidosis: new tricks for old dogs?35
Chicken or the egg? Critical illness and mental health34
Cardiac injury in COVID-1934
The REMDACTA trial: do interleukin receptor antagonists provide additional benefit in COVID-19?34
Measuring patient’s effort on the ventilator34
The environmental impact of laboratory measurements in high-resource ICUs34
Long-term outcomes with haloperidol versus placebo in acutely admitted adult ICU patients with delirium33
Immune-mediated thrombotic thrombocytopenic purpura: don’t miss the boat32
Learning from our unit’s first exorcism31
The relationship between treatment limitations and pressure on intensive care units in elderly patients31
ICU-specific factors associated with venous thromboembolism and bleeding31
Bedside-available strategies to minimise P-SILI and VILI during ARDS31
The association of the COVID-19 pandemic and short-term outcomes of non-COVID-19 critically ill patients: an observational cohort study in Brazilian ICUs31
Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis31
Correction: Rapid multiplex PCR panels for the management of ventilator-associated pneumonia: pondering strengths and weaknesses30
Weaning strategy in patients at low-to-medium risk of extubation failure30
The new global definition of ARDS loses one of the first games: a chromatic advice29
Sometimes, less is just less…29
Correction to: Role of total lung stress on the progression of early COVID‑19 pneumonia29
Federated data access and federated learning: improved data sharing, AI model development, and learning in intensive care29
Norepinephrine dose and concentration reporting: a closer look at the fine print29
One-year outcomes in acute respiratory distress syndrome survivors: COVID-19 versus seasonal influenza or pneumonia29
Rapid syndromic multiplex PCR panels for the management of ventilator-associated lower respiratory tract infections: pondering important limitations. Author’s reply29
Navigating complex interventions in post-ICU care: insights from a randomized clinical trial of post-intensive care multidisciplinary consultations28
Acute respiratory distress syndrome guidelines: oceans apart or rivers that merge?28
Understanding purpura fulminans in adult patients28
Use of vasopressors and inotropes in ECMO28
Correction: The role of centre and country factors on process and outcome indicators in critically ill patients with hospital-acquired bloodstream infections28
Sequencing interventions in ARDS: the critical role of timing and order in standardized management28
Choice of priors: how much scepticism is appropriate?27
Pick your prior: scepticism about sceptical prior beliefs27
Noninvasive neuromonitoring in acute brain injured patients27
Workplace equity for clinicians with a disability: why it matters for all26
Correction: Management of hematological patients requiring emergency chemotherapy in the intensive care unit26
The choice of crystalloid type in the intensive care unit is likely more complex than expected: should doubt benefit the patient?26
Broad use of processed EEG: ready for prime time yet?26
Routine colonoscopy in patients with high risk of non-occlusive mesenteric ischemia26
Oxygen thresholds in critically ill patients: need for personalized targets26
Long-term outcomes of critically ill patients with hematological malignancies: what is the impact of the coronavirus disease 2019 pandemic?26
Treating necrotizing skin and soft-tissue infections26
Redefining the paradigm: incentivizing the peer review process for scientific advancement25
A double plea for dyspnea as the next great cause of all ICU professions and for caution about the dyspnea-breathlessness equivalence25
Federated learning: a step in the right direction to improve data equity25
18F-fluorodeoxyglucose positron emission tomography/computed tomography differentiates between pneumonia and atelectasis in a mechanically ventilated patient25
Sex-, gender-, and diversity-based analysis of the Intensive Care Medicine Journal’s most-cited articles of 202325
Post-intensive care unit follow-up: don’t stop it now!25
Critical insights into venoarterial extracorporeal membrane oxygenation outcomes in immunocompromised patients: addressing uncertainties in cause of death and treatment strategies25
Citrate anticoagulation for continuous renal replacement therapy24
The limitations of evidence-based medicine compel the practice of personalized medicine24
The use of echocardiography in the management of shock in critical care: a prospective, multi-centre, observational study24
Major adverse kidney events as an endpoint in acute kidney injury trials: is it time for a RE-MAKE?24
Venoarterial extracorporeal membrane oxygenation is routinely used in the intensive care unit, but are patients ready for it?24
Challenges in optimizing the treatment of Pneumocystis pneumonia in the intensive care unit. Author’s reply24
Long-term outcomes in nutrition trials: after all, this is what our patients are looking for!!24
Treating acute encephalitis24
Should we abandon the CAM-ICU and practice “humanizing care” for all patients?23
Personalized oxygen targets are needed for extracorporeal membrane oxygenation23
Using the helmet23
Navigating the ventilator in acute brain injury: a forceful call for clarity and caution23
Quantifying benefit and harm of extracorporeal life support in cardiogenic shock complicating acute myocardial infarction23
Severe Pneumocystis jirovecii pneumonia: time to reassess our practices23
“It’s all about setting the stage.” The nurse facilitator trial: perceived outcomes and implementation issues. A qualitative study among ICU clinicians and nurse facilitators23
Central venous catheter-related infection: does insertion site still matter? A French multicentric cohort study22
Fluid responsiveness in acute respiratory distress syndrome patients: a post hoc analysis of the HEMOPRED study22
Towards improved management of pulmonary herpes simplex virus and cytomegalovirus in COVID-19 ARDS: a future perspective22
Challenging management dogma where evidence is non-existent, weak, or outdated: part II21
Effect of the 1-h bundle on mortality in patients with suspected sepsis in the emergency department: faster is better for the sicker ones! Author’s reply21
Set reliable hypotheses when using ICEMAN to assess the credibility of subgroup analysis21
Preventing stress ulcer bleeding21
Fludrocortisone dose–response relationship in septic shock: a randomised phase II trial21
No ventilation, no ARDS: insights from four-dimensional computed tomography as dynamic imaging21
Early physiologic changes after awake prone positioning predict clinical outcomes in patients with acute hypoxemic respiratory failure20
Early endothelial injury in cardiogenic shock patients on venoarterial ECMO20
Effect of proning and recruitment on physio-anatomical variables in COVID-19 pneumonia20
Correction to: Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial20
Prognostication model for traumatic brain injury based on age and white matter diffusion metrics in MRI brain. Author’s reply20
The choice of resuscitation fluids—Ionic composition matters. Author’s reply20
The effects of pantoprazole vs. placebo on 1-year outcomes, resource use and employment status in ICU patients at risk for gastrointestinal bleeding: a secondary analysis of the SUP-ICU trial20
Critical care admissions and outcomes in pregnant and postpartum women: a systematic review20
Chlorhexidine-alcohol compared with povidone-iodine-alcohol skin antisepsis protocols in major cardiac surgery: a randomized clinical trial20
The role of policy and law in shaping the ethics and quality of end-of-life care in intensive care20
Correction to: Education to save lives: C19SPACE, the COVID19 Skills PrepAration CoursE20
Addressing key considerations in the use of 20% human albumin for fluid resuscitation in cardiac surgery. Author’s reply20
Coupled plasma filtration and adsorption for the treatment of septic shock20
Anesthetic drugs for rapid sequence intubation: ketamine, but what dose?19
Development and validation of early prediction models for new-onset functional impairment at hospital discharge of ICU admission19
Considerations for β-lactam antimicrobial continuous infusion. Authors’ reply to Massart et al. and Marzaroli et al.19
Phrenic nerve stimulation to protect the diaphragm, lung, and brain during mechanical ventilation19
Time course of physiological variables during inter-hospital helicopter transport of ventilated COVID-19 patients19
Where is the imperceptible difference?19
Basic ultrasound skill for intensivists: future scope for expansion of the recommendations of the European Society of Intensive Care Medicine19
What about permissive acidosis?19
Terlipressin use in hepatorenal syndrome-acute kidney injury in cirrhosis19
Cardiac manifestations in critically ill patients with COVID-19: do we really know what hit us?19
End-of-life care awareness in a low–middle-income country: a plea for improvement19
Ten myths about albumin: do not forget the endothelium19
Nicotine patches in patients on mechanical ventilation for severe COVID-19: a randomized, double-blind, placebo-controlled, multicentre trial18
The role of artificial intelligence in life-sustaining treatment decisions: current state and future considerations18
Lung recruitment18
Heart rate control in septic shock—echocardiographic evaluation and monitoring should be standard18
Another trial for the TARGET trial. Author’s reply18
The TARGET trial as a plea for model-informed precision dosing of piperacillin/tazobactam in patients with sepsis18
The provision of echocardiography in critical care: a multi-centre survey of the UK and Crown Dependencies18
Full enteral nutrition should be avoided among patients with high vasopressor dose and low flow state18
Rethinking energy and protein provision for critically ill patients18
Artificial Intelligence interpretation of chest radiographs in intensive care. Ready for prime time?17
Beyond failure or success: reflections on the ethical justifications for time-limited trial of intensive care17
Severe hemophagocytic lymphohistiocytosis in kidney transplant recipient: the etiology is on the tip of the tongue!17
Helmet noninvasive support in hypoxemic respiratory failure17
Basic ultrasound skill for intensivists: future scope for expansion of the recommendations of the European Society of Intensive Care Medicine. Author's reply17
Characterising right ventricular dysfunction in acute respiratory distress syndrome due to COVID-19: which measurements are best?17
Psychological distress and morbidity of family members experiencing virtual visiting in intensive care during COVID-19: an observational cohort study17
Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia17
[18F]FDG PET/CT to diagnose inflammation in critically ill immunocompromised patients17
Immune enhancement in patients with predicted severe acute necrotising pancreatitis: a multicentre double-blind randomised controlled trial17
Is (1,3)-β-d-glucan useless to guide antifungal therapy in ICU?17
The moral problems with time-limited trials at the end-of-life, especially when clinicians and patients have different goals16
How to improve intubation in the intensive care unit. Update on knowledge and devices16
Long-term outcomes of dexamethasone 12 mg versus 6 mg in patients with COVID-19 and severe hypoxaemia16
Serum chloride concentration and outcomes in adults receiving intravenous fluid therapy with a balanced crystalloid solution or 0.9% sodium chloride16
High-risk pulmonary embolism in the intensive care unit16
Plasma exchange in the intensive care unit: a narrative review16
How we use ultrasound in the initial management of the critically ill trauma patient16
Correction to: Noninvasive respiratory support in intensive care medicine16
Trash in/trash out? Using routinely collected clinical data for data science in the ICU: Con16
Moving from bytes to bedside: a systematic review on the use of artificial intelligence in the intensive care unit16
Optimizing ICU antifungal therapy: overcoming pharmacokinetic limitations with combination strategies15
Greenery and outdoor facilities to improve the wellbeing of critically ill patients, their families and caregivers: things to consider15
Safety and efficacy of artesunate treatment in severely injured patients with traumatic hemorrhage. The TOP-ART randomized clinical trial15
Early prognostic value of non-invasive intracranial pressure methods in brain-injured patients15
How environmental impact is considered in economic evaluations of critical care: a scoping review15
Daily point-of-care ultrasound-assessment of central venous catheter-related thrombosis in critically ill patients: a prospective multicenter study15
Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury15
Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions15
Supporting the bereaved child in the adult ICU: let’s take the first step!15
Dose of norepinephrine: the devil is in the details15
Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis15
Driving pressure: applying the concept at the bedside15
The effectiveness of alkaline phosphatase in sepsis-associated acute kidney injury15
Publisher Correction: EFFECT of daily antiseptic bathing with octenidine on ICU-acquired bacteremia and ICU-acquired multidrug-resistant organisms: a multicenter, cluster-randomized, double-blind, pla15
Dyspnoea in acutely ill mechanically ventilated adult patients: an ERS/ESICM statement15
Targeted temperature management following out-of-hospital cardiac arrest: a systematic review and network meta-analysis of temperature targets15
Interferon gamma-1b for the prevention of hospital-acquired pneumonia in critically ill patients: a phase 2, placebo-controlled randomized clinical trial15
No clinically relevant removal of meropenem by cytokine adsorber CytoSorb® in critically ill patients with sepsis or septic shock14
Management of chimeric antigen receptor T (CAR-T) cell-associated toxicities14
High-risk pulmonary embolism: the significance and perspectives of pulmonary reperfusion14
Sedatives in neurocritical care: the old, the new, the future14
European Society of Intensive Care Medicine guidelines on end of life and palliative care in the intensive care unit14
The AKI care bundle: all bundle components are created equal—are they?14
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