Drug Metabolism Reviews

Papers
(The TQCC of Drug Metabolism Reviews is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)
ArticleCitations
Cytochrome P450 expression and regulation in the brain49
The development and hepatotoxicity of acetaminophen: reviewing over a century of progress39
Recent biotechnological approaches for treatment of novel COVID-19: from bench to clinical trial34
Pharmacology of apocynin: a natural acetophenone33
Drug metabolic stability in early drug discovery to develop potential lead compounds28
Toxicity mechanisms of nanoparticles in the male reproductive system25
Regulation of cytochrome P450 enzyme activity and expression by nitric oxide in the context of inflammatory disease21
Pharmacogenomics in the era of next generation sequencing – from byte to bedside19
Mechanistic studies on the drug metabolism and toxicity originating from cytochromes P45018
Dioscorea bulbifera L.-induced hepatotoxicity and involvement of metabolic activation of furanoterpenoids17
Ibuprofen-based advanced therapeutics: breaking the inflammatory link in cancer, neurodegeneration, and diseases16
Toxicogenomics of drug induced liver injury – from mechanistic understanding to early prediction.16
In quest of a new therapeutic approach in COVID-19: the endocannabinoid system15
Recent developments inin vitroandin vivomodels for improved translation of preclinical pharmacokinetics and pharmacodynamics data15
The role of UDP-glycosyltransferases in xenobioticresistance14
Through a glass, darkly? HepaRG and HepG2 cells as models of human phase I drug metabolism14
The broad-spectrum antiviral recommendations for drug discovery against COVID-1914
Effects of intestinal flora on pharmacokinetics and pharmacodynamics of drugs13
Biotransformation of arsenic trioxide by AS3MT favors eradication of acute promyelocytic leukemia: revealing the hidden facts13
Janus nanoparticles: an efficient intelligent modern nanostructure for eradicating cancer12
What dominates the changeable pharmacokinetics of natural sesquiterpene lactones and diterpene lactones: a review focusing on absorption and metabolism12
Molecular modeling approaches to address drug-metabolizing enzymes (DMEs) mediated chemoresistance: a review11
The relationship between UGT1A1 gene & various diseases and prevention strategies11
The multifaceted role of cytochrome P450-Derived arachidonic acid metabolites in diabetes and diabetic cardiomyopathy11
Implication of metabolomics and transporter modulation based strategies to minimize multidrug resistance and enhance site-specific bioavailability: a needful consideration toward modern anticancer dru11
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