Drug Metabolism Reviews

Papers
(The TQCC of Drug Metabolism Reviews is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
CYP24A1: the pivotal regulator of vitamin D homeostasis, pathophysiology in metabolic and genetic disease, and emerging target for precision medicine55
Drug transporters in drug disposition – the year 2022 in review41
New strategy for rational use of antihypertensive drugs in clinical practice in high-altitude hypoxic environments38
Differential modulation of cytochrome P450 enzymes by arsenicals in non-human experimental models27
Enantioselectivity in some physiological and pathophysiological roles of hydroxyeicosatetraenoic acids23
An in-depth review of PPARγ modulators as anti-diabetes therapeutics22
Phase II metabolism in xenobiotic biotransformation: general mechanisms and the underestimated role of microbial systems20
A critical review of analytical tools for the detection of spironolactone and its metabolites18
Mechanisms of intestinal pharmacokinetic natural product-drug interactions18
Redox enzyme networks shaping cancer drug metabolism and therapeutic resistance18
Multimolecular interactions from Chinese medicines activate nuclear receptor conformational changes: a potential strategy for anti-inflammatory therapy17
Cytochrome P450-mediated carbon-carbon bond formation in drug metabolism16
Assessing and mitigating pH-mediated DDI risks in drug development – formulation approaches and clinical considerations15
Metabolism of new drug modalities research advances – 2024 year in review14
Transporter-mediated drug-drug interactions: regulatory guidelines, in vitro and in vivo methodologies and translation, special population13
Genetic determinants of paclitaxel-induced peripheral neuropathy: a review of current literature12
Biopolymers as promising vehicles for drug delivery to the brain12
Drug transporters in drug disposition – highlights from the year 202412
Biotransformation research advances—2025 year in review11
Molecular insights into doxorubicin-induced cardiotoxicity and phytochemical-based cardioprotection: challenges and future strategies11
Pharmacomicrobiomics in precision pharmacotherapy: bidirectional microbial-drug interactions as a key determinant of therapeutic response11
Scaling factors to inform in vitro - in vivo extrapolation from preclinical and livestock animals: state o10
Metabolic activation of tyrosine kinase inhibitors: recent advance and further clinical practice10
Clinical pharmacokinetics of nebivolol: a systematic review9
Favipiravir, remdesivir, and lopinavir: metabolites, degradation products and their analytical methods9
Effects of intestinal flora on pharmacokinetics and pharmacodynamics of drugs9
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