OOIR: Observatory of International Research

Papers

(The H4-Index of Annual Review of Pharmacology and Toxicology is 33. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
How Biologics Have Changed the Drug Discovery Landscape	174
Introduction to the Theme “New Approaches, Technology, and Techniques That Advance Pharmacology and Toxicology”	149
Pharmacology of Intestinal Inflammation and Repair	148
The Promises and Prospects of Long-Acting Therapeutics for Treatment and Prevention of Infectious Diseases	120
Age-Related Perioperative Neurocognitive Disorders: Experimental Models and Druggable Targets	116
Orexin Receptor Antagonism: Normalizing Sleep Architecture in Old Age and Disease	89
Opportunities for Microphysiological Systems in Toxicity Testing of New Drug Modalities	84
Evolving Approaches for Pharmacological Therapy of Obesity	84
Introduction to the Theme “Pharmacological Individuality: New Insights and Strategies for Personalized and Precise Drug Treatment”	83
Mitogen-Activated Protein Kinase Phosphatases: No Longer Undruggable?	82
Introduction to the Theme “Development of New Drugs: Moving from the Bench to Bedside and Improved Patient Care”	82
Community Aspects of HIV Biomedical Prevention	79
Incretin Signaling Neighborhoods and Adverse Drug Reactions	75
Multisystem Toxicity of E-Cigarettes in Preclinical and Clinical Studies: Pathophysiologic Effects of E-Cigarette Aerosol Exposures from Head to Toe	73
Inhibitors of Intracellular RyR2 Calcium Release Channels as Therapeutic Agents in Arrhythmogenic Heart Diseases	70
Hear and Now: Ongoing Clinical Trials to Prevent Drug-Induced Hearing Loss	70
Gβγ Signaling: Lessons Across the Cellular Multiverse	69
Microplastics and Atherosclerosis: Mechanisms	60
GPCR Biosensors to Study Conformational Dynamics and Signaling in Drug Discovery	58
Health Digital Twins in Life Science and Health Care Innovation	57
G Protein–Coupled Receptor Heteromers in Brain: Functional and Therapeutic Importance in Neuropsychiatric Disorders	53
OAT, OATP, and MRP Drug Transporters and the Remote Sensing and Signaling Theory	52
Synthetic Cannabinoids: A Pharmacological and Toxicological Overview	46
Targeting G Protein–Coupled Receptors in Immuno-Oncological Therapies	45
Pharmacogenetic Panel Testing: A Review of Current Practice and Potential for Clinical Implementation	44

RNA Splicing as a Therapeutic Target in Cancer	44
Immunoregulation of Liver Fibrosis: New Opportunities for Antifibrotic Therapy	43
Pharmacogenetics of Antiplatelet Therapy	43
Cognitive Impairment Associated with Schizophrenia: From Pathophysiology to Treatment	42
Translational In Vivo Assays in Behavioral Biology	41
A Mechanistic Framework for Repurposing FDA-Approved Drugs to Combat Antimicrobial Resistance: The Case of Staphylococcus aureus	40
Prospects for Disease Slowing in Parkinson Disease	39
G Protein–Coupled Estrogen Receptor GPER: Molecular Pharmacology and Therapeutic Applications	35
What Structural Biology Tells Us About the Mode of Action and Detection of Toxicants	33