American Journal of Physiology-Heart and Circulatory Physiology

Article	Citations
Glycoprotein 130 orchestrates signal transduction network to promote cardiomyocyte proliferation for normal growth	113
Reverse is a complicated direction	79
A minimally invasive swine model of chronic kidney disease-associated heart failure	78
Relationship between LDL-cholesterol, small and dense LDL particles, and mRNA expression in a cohort of African Americans	66
Extracellular matrix instability and chronic inflammation underlie maladaptive right ventricular pressure overload remodeling and failure in male mice	65
Inhibition of kinin B1 receptor alleviates SARS-CoV-2-induced long-lasting cardiovascular complications	61
Intracoronary ECG ST-segment shift remission time during reactive myocardial hyperemia: a new method to assess hemodynamic coronary stenosis severity	57
Cardiac remodeling in heart disease and the importance of thyroid hormones	52
An ovary-intact postmenopausal HFpEF mouse model; menopause is more than just estrogen deficiency	51
Reply to Schmitz	50
Calcium signaling in endothelial and vascular smooth muscle cells: sex differences and the influence of estrogens and androgens	47
Reply to De Mey et al.	43
Metabolic theory of preeclampsia: implications for maternal cardiovascular health	43
Reply to Trimaille et al.	42
Effect of cardiomyocyte-specific lipid phosphate phosphatase 3 overexpression on high-fat diet-induced cardiometabolic dysfunction in mice	42
Cardiovascular consequences of preeclampsia: Is the reactivity to stress the missing piece of the puzzle?	41
Nervy Issues of Fatty Tissues: a Deeper Dig into the innervation of fat	39
Reply to Blaustein et al.	39
The meaning of volume responsiveness and its relationship to venous return	38
The FXYD1 protein plays a protective role against pulmonary hypertension and arterial remodeling via redox and inflammatory mechanisms	38
Volume responsiveness revisited: an observational multicenter study of continuous versus binary outcomes combining echocardiography and venous return physiology	38
Adverse pregnancy outcomes and renal-vascular function in the early years after delivery	38
Hemodynamic simulation of complete transposition of the great arteries for optimal treatment strategies based on its circulatory physiology	37
Differential effects of myosin activators on myocardial contractile function in nonfailing and failing human hearts	36
Prenatal dexamethasone programs autonomic dysregulation in female rats	35

Associations of circulating T-cell subsets with endothelial function: the Multi-Ethnic Study of Atherosclerosis	34
Long-term hemodynamic responses and reverse remodeling after pharmacotherapy in HFpEF versus HFrEF: a systematic review and meta-analysis	33
High variability in the reproducibility of key hemodynamic responses to head-up tilt	31
Sexual dimorphism in right ventricular adaptation to pressure overload involves differential angiogenic response	30
Lower estimates of myocardial perfusion are associated with greater aortic perivascular adipose tissue density in humans independent of aortic stiffness	30
Sexual dimorphism in the downregulation of extracellular matrix genes contributes to aortic stiffness in female mice	28
Reply to Liu et al.	27
Impact of coronary hyperemia on collateral flow correction of coronary microvascular resistance indices	27
Correlations between salivary- and blood-derived gonadal hormone assessments and implications for inclusion of female participants in research studies	26
MicroRNA in pediatric pulmonary hypertension microRNA profiling to inform disease classification, severity, and treatment response in pediatric pulmonary hypertension	26
Habituation attenuates the sex-specific associations between ischemic pain, blood pressure, and arterial stiffness in young adults	25
Parental obesity predisposes male and female offspring to exacerbated cardiac dysfunction and increased mortality after myocardial infarction	25
Mechanism and potential treatment of the “no reflow” phenomenon after acute myocardial infarction: role of pericytes and GPR39	25
Isoproterenol improves hemodynamics and right ventricle-pulmonary artery coupling after heart transplantation	25
Coronary vasodilation mediated by T cells expressing choline acetyltransferase	25
Regulation of cerebrovascular compliance compared with forearm vascular compliance in humans: a pharmacological study	25
Exercise in hypertrophic cardiomyopathy: restrict or rethink	25
Sex differences in cardiovascular disease and dysregulation in Down syndrome	24
Lower hemoglobin levels associate with higher baroreflex sensitivity and heart rate variability	24
An in silico approach to understanding the interaction between cardiovascular and pulmonary lymphatic dysfunction	24
Therapy-naïve malignancy causes cardiovascular disease: a state-of-the-art cardio-oncology perspective	24
Empagliflozin attenuates arrhythmogenesis in diabetic cardiomyopathy by normalizing intracellular Ca2+ handling in ventricular cardiomyocytes	24
Partial sleep restriction and blood pressure during exercise: surprising findings and future directions	23
Activation of the nonneuronal cholinergic cardiac system by hypoxic preconditioning protects isolated adult cardiomyocytes from hypoxia/reoxygenation injury	23
Calcium handling dysfunction and cardiac damage following acute ventricular preload challenge in the dystrophin-deficient mouse heart	23
A novel role for PGE2-EP4 in the developmental programming of the mouse ductus arteriosus: consequences for vessel maturation and function	23
Activation of IP3R in atrial cardiomyocytes leads to generation of cytosolic cAMP	23
Effect of insulin on indices of cerebral blood flow and cerebrovascular compliance in young adults	23
Deletion of DWORF does not affect cardiac function in aging and in PLN-R14del cardiomyopathy	22
Spring cleaning: freshening up the portfolio	22
Innervation of adipocytes is limited in mouse perivascular adipose tissue	22
Diving deep toward the bottlenose dolphins’ antiarterial aging secret: insight for the circulating milieu as a novel mechanism to preserve endothelial health	22
IL-33 supplementation improves uterine artery resistance and maternal hypertension in response to placental ischemia	22
Impaired microvascular insulin-dependent dilation in women with a history of gestational diabetes	22
More than just a small left ventricle: the right ventricular fibroblast and ECM in health and disease	22
Scratching beneath the surface: IL4Rα blockade and the progression from myocardial ischemic injury to heart failure	21
Understanding the estrogen paradox of pulmonary arterial hypertension in the context of right ventricular function	21
Clinical physiology: the crucial role of MRI in evaluation of peripheral artery disease	21
Real-time in vivo thoracic spinal glutamate sensing during myocardial ischemia	21
Expanding the supply of donor hearts through donation after circulatory death	21
Multidirectional blood flow in the femoral artery via vector flow imaging: Doppler ultrasound imaging insights	21
Exercise-induced cardiac troponin release in athletes with versus without coronary atherosclerosis	21
Empagliflozin improves circulating vascular regenerative cell content in people without diabetes with risk factors for adverse cardiac remodeling	21
Developmental nicotine exposure alters cardiovascular structure and function in neonatal and juvenile rats	20
Combination of reduced uterine perfusion pressure and leptin infusion as a novel model of preeclampsia	20
Proteolytic degradation of atrial sarcomere proteins underlies contractile defects in atrial fibrillation	20
Sildenafil administration improves right ventricular function on 4D flow MRI in young adults born premature	20
Sertraline-induced 5-HT dysregulation in mouse cardiomyocytes and the impact on calcium handling	20
Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum	20
Gene expression networks in endothelial cells from failing human hearts	20

Hypoxia-inducible factor-2α enhances neutrophil survival to promote cardiac injury following myocardial infarction	20
The importance of myosin ubiquitination status for cardiac remodeling: USP20 has entered the chat	20
Electrical remodeling of atrioventricular junction: a study on retrogradely perfused chick embryonic heart	20
Prenatal stress induces sex- and tissue-specific alterations in insulin pathway of Wistar rats offspring	20
Biomarkers of intestinal permeability are associated with inflammation in metabolically healthy obesity but not normal-weight obesity	20
What frozen human hearts can tell us about treating heart failure	20
Computer modeling to predict balloon pulmonary angioplasty success	19
Ethanol: striking the cardiovascular system by harming the gut microbiota	19
Enhanced endothelial barrier function by monoclonal antibody activation of vascular endothelial cadherin	19
Race-specific changes in endothelial inflammation and microRNA in response to an acute inflammatory stimulus	19
Central command-related increases in blood velocity of anterior cerebral artery and prefrontal oxygenation at the onset of voluntary tapping	19
Reperfused vs. nonreperfused myocardial infarction: when to use which model	19
Cardiac PANK1 deletion exacerbates ventricular dysfunction during pressure overload	18
Characterization of βARKct engineered cellular extracellular vesicles and model specific cardioprotection	18
Sex differences in the impact of parental obesity on offspring cardiac SIRT3 expression, mitochondrial efficiency, and diastolic function early in life	18
Angiotensin II type 1 receptor is involved in flow-induced vasomotor responses of isolated middle cerebral arteries: role of oxidative stress	18
Cardiac myosin binding protein-C phosphorylation accelerates β-cardiac myosin detachment rate in mouse myocardium	18
Diabetes mellitus disrupts lncRNA Malat1 regulation of cardiac mitochondrial genome-encoded protein expression	18
SGLT2 inhibition potentiates the cardiovascular, renal, and metabolic effects of sGC stimulation in hypertensive rats with prolonged exposure to high-fat diet	17
FoxO4 controls sGCβ transcription in vascular smooth muscle	17
Impact of angiotensin II receptor antagonism on the sex-selective dysregulation of cardiovascular function induced by in utero dexamethasone exposure	17
Modulation of p66Shc impairs cerebrovascular myogenic tone in low renin but not low nitric oxide models of systemic hypertension	17
Deficiency in nebulin repeats of sarcomeric nebulette is detrimental for cardiomyocyte tolerance to exercise and biomechanical stress	17
Serum dihydrotestosterone levels are associated with adverse myocardial remodeling in patients with severe aortic valve stenosis before and after aortic valve replacement	17
Comprehensive analyses of the inotropic compound omecamtiv mecarbil in rat and human cardiac preparations	17
Luseogliflozin, a sodium-glucose cotransporter-2 inhibitor, reverses cerebrovascular dysfunction and cognitive impairments in 18-mo-old diabetic animals	17
Prenatal ethanol exposure impairs the conduction delay at the atrioventricular junction in the looping heart	17
Find the stimulus, save the heart: a heroes’ story	17
Ensemble machine learning model identifies patients with HFpEF from matrix-related plasma biomarkers	16
New insights into mechanisms of endothelial insulin resistance in type 2 diabetes	16
Female rats are less prone to clinical heart failure than male rats in a juvenile rat model of right ventricular pressure load	16
Blood pressure oscillations impact signal-averaged sympathetic transduction of blood pressure: implications for the association with resting sympathetic outflow	16
Gender-affirming estrogen therapy route of administration and cardiovascular risk: a systematic review and narrative synthesis	16
Global Reach 2018: sympathetic neural and hemodynamic responses to submaximal exercise in Andeans with and without chronic mountain sickness	16
Carotid intima-media thickness and flow-mediated dilation do not predict acute in-hospital outcomes in patients hospitalized with COVID-19	16
Long-term cardiovascular health status and physical functioning of nonhospitalized patients with COVID-19 compared with non-COVID-19 controls	16
Sex-dependent attenuating effects of capsaicin administration on the mechanoreflex in healthy rats	15
Endothelial-derived extracellular vesicles from obese/hypertensive adults increase factors associated with hypertrophy and fibrosis in cardiomyocytes	15
Carotid dysfunction in senescent female mice is mediated by increased α1A‐adrenoceptor activity and COX-derived vasoconstrictor prostanoids	15
The importance of biological sex in cardiac cachexia	15
Obesity blunts amelioration of cardiac hypertrophy and fibrosis by human mesenchymal stem/stromal cell-derived extracellular vesicles	15
Augmented T-cell mitochondrial reactive oxygen species in adults with major depressive disorder	15
Myocardial injury, troponin release, and cardiomyocyte death in brief ischemia, failure, and ventricular remodeling	15
Mechanisms and clinical implications of endothelium-dependent vasomotor dysfunction in coronary microvasculature	15
Ischemic damage to every segment of the oxidative phosphorylation cascade elevates ETC driving force and ROS production in cardiac mitochondria	15
Sympathoexcitatory responses to renal chemosensitive stimuli are exaggerated at nighttime in rats	15
Impact of exercise training on pulse wave velocity in healthy and clinical populations: a systematic review of systematic reviews	15
Placenta-targeted treatment with nMitoQ prevents an endothelin receptor-A pathway cardiac phenotype observed in adult male offspring exposed to hypoxia in utero	15
Short-term salicylate treatment improves microvascular endothelium-dependent dilation in young adults with major depressive disorder	15
Hypertension promotes microbial translocation and dysbiotic shifts in the fecal microbiome of nonhuman primates	15
Implications of Sm22α-Cre expression in keratinocytes and unanticipated inflammatory skin lesion in a model of atherosclerosis	14
Nonmyocytes as electrophysiological contributors to cardiac excitation and conduction	14
Accelerated atherosclerosis in beta-thalassemia	14
Widespread intracoronary allogeneic cardiosphere-derived cell therapy with and without cyclosporine in reperfused myocardial infarction	14
Evaluation of early bilateral ovariectomy in mice as a model of left heart disease	14
Sclerostin ablation prevents aortic valve stenosis in mice	14
Anthracycline cardiotoxicity is exacerbated by global p38β genetic ablation in a sexually dimorphic manner but unaltered by cardiomyocyte-specific p38α loss	14
Refining the reproducibility of a murine model of stress-induced reversible cardiomyopathy	14
NADPH oxidase overexpression and mitochondrial OxPhos impairment are more profound in human hearts donated after circulatory death than brain death	14
Cardiac myosin motor deficits are associated with left ventricular dysfunction in human ischemic heart failure	14
Taking to “heart” the proposed legislation for permanent daylight saving time	14
One method does not fit all: the importance of sex and using multiple methods to assess cardiac reserve in mice	14
A novel method for the percutaneous induction of myocardial infarction by occlusion of small coronary arteries in the rabbit	14
Slower shortening kinetics of cardiac muscle performing Windkessel work-loops increase mechanical efficiency	14
The protective effect of remote ischemic conditioning is lost in patients with hypercholesterolemia	13
The multifaceted roles of red blood cells in health and disease	13
Loss of lung microvascular endothelial Piezo2 expression impairs NO synthesis, induces EndMT, and is associated with pulmonary hypertension	13
Creating diversity, equity, inclusion, and accessibility statements for your CV: a resource guide to effectiveness and comprehensiveness	13
Hypobaric hypoxia and cardiac baroreflex sensitivity in young women	13
New cardiac targets for empagliflozin: O-GlcNAcylation, CaMKII, and calcium handling	13
USP20 deletion promotes eccentric cardiac remodeling in response to pressure overload and increases mortality	13
Immune interactions in pembrolizumab (PD-1 inhibitor) cancer therapy and cardiovascular complications	13
Disturbed flow in the juxta-anastomotic area of an arteriovenous fistula correlates with endothelial loss, acute thrombus formation, and neointimal hyperplasia	13
Interplay between temporal and spatial dispersion of repolarization in the initiation and perpetuation of torsades de pointes in the chronic atrioventricular block dog	13
Understanding Takotsubo syndrome: first evaluate your mouse model	13
Cell therapy attenuates endothelial dysfunction in hypertensive rats with heart failure and preserved ejection fraction	13
On the use and misuse of cerebral hemodynamics terminology using transcranial Doppler ultrasound: a call for standardization	13
Chronic perinatal hypoxia delays cardiac maturation in a mouse model for cyanotic congenital heart disease	13
Moderate aerobic exercise prevents matrix degradation and death in a mouse model of aortic dissection and aneurysm	13
Guidelines for assessing ventricular pressure-volume relationships in rodents	13

Cardiac autonomic function is preserved in young adults with major depressive disorder	13
Role of perivascular nerve and sensory neurotransmitter dysfunction in inflammatory bowel disease	12
Vasomotor symptoms of menopause, autonomic dysfunction, and cardiovascular disease	12
Female sex-specific considerations to improve rigor and reproducibility in cardiovascular research	12
Reply to Madias	12
NLRP3 inflammasome-induced pyroptosis and serum ASC specks are increased in patients with cardiogenic shock	12
Reply to Cristóbal et al.	12
Mannitol and hyponatremia regulate cardiac ventricular conduction in the context of sodium channel loss of function	12
Liposomal nanocarriers of preassembled glycocalyx expeditiously restore endothelial glycocalyx in endotoxemia	12
Deletion of the Aryl Hydrocarbon Receptor in Endothelial Cells Improves Ischemic Angiogenesis in Chronic Kidney Disease	12
An in silico study of the effects of cardiovascular aging on carotid flow waveforms and indexes in a virtual population	12
Loss of talin in cardiac fibroblasts results in augmented ventricular cardiomyocyte hypertrophy in response to pressure overload	12
Reduced microvascular flow-mediated dilation in Syrian hamsters lacking δ-sarcoglycan is caused by increased oxidative stress	12
Reply to Boedtkjer and Aalkjaer	12
Cerebral arteriolar and neurovascular dysfunction after chemically induced menopause in mice	12
Sex differences in microvascular function and arterial hemodynamics in nondialysis chronic kidney disease	12
Deacetylation mimetic mutation of mitochondrial SOD2 attenuates ANG II-induced hypertension by protecting against oxidative stress and inflammation	12
Glial cell activity in cardiovascular diseases and risk of acute myocardial infarction	12
Mechanisms of pulmonary vascular dysfunction in pulmonary hypertension and implications for novel therapies	12
Targeted Circulating Lipid Mediators and Immune Cell Gene Transcripts After ST-Elevation Myocardial Infarction	12
Prognostic circulatory signature metabolites of stable versus unstable angina: an application of NMR spectroscopy	12
Allostatic load and cardiometabolic health in a young adult South African population: the African-PREDICT study	11
Interaction of macro- and microvascular function underlies brachial artery flow-mediated dilation in humans	11
Vascular complications from SARS-CoV2: a unique finding or a common feature of viral infections?	11
The role of mechanosignaling in the control of myocardial mass	11
Microvascular dysfunction and neurovascular uncoupling are exacerbated in peripheral artery disease, increasing the risk of cognitive decline in older adults	11
Cardiorespiratory Fitness is Associated with Estimates of Myocardial Perfusion: Influence of Age and Sex	11
The effects of chronic stress on rat heart function following regional ischemia: a sex-dependent investigation	11
Carvedilol and exercise combination therapy improves systolic but not diastolic function and reduces plasma osteopontin in Col4a3−/− Alport mice	11
Cardiac health, type I collagen, and aging in the oim/oim mouse model of osteogenesis imperfecta and a cohort of adults with OI	11
Cardioprotective effects of exercise on ischemic heart disease: digging into the downstream signaling pathways	11
Leveraging circulating DNase I Activity to Detect Silent Coronary Artery Disease among Hypertensive Diabetes Individuals	11
Insights into the associations between the gut microbiome, its metabolites, and heart failure	11
Sigmoidal heart rate response pattern during exercise in patients with chronic heart failure	11
Role of arterial impairment in preeclampsia: should the paradigm shift?	11
Activation of IP3R in atrial cardiomyocytes leads to generation of cytosolic cAMP	11
Older females but not males exhibit increases in cerebral blood velocity, despite similar pulsatility increases after high-intensity resistance exercise	11
Impacts of circulating microRNAs in exercise-induced vascular remodeling	11
Hemorheological, cardiorespiratory, and cerebrovascular effects of pentoxifylline following acclimatization to 3,800 m	11
ADAM17 cleaves the insulin receptor ectodomain on endothelial cells and causes vascular insulin resistance	11
(Re)modeling high-salt diet-induced hypertension in mice	11
Heart and health behavior responses to GLP-1 receptor agonists: a 12-wk study using wearable technology and causal inference	11
Further refining of the murine model of intraperitoneal injection of isoproterenol-induced takotsubo syndrome	11
Global Genomic Profile of Hippocampal Endothelial cells by single nuclei RNA sequencing in Female Diabetic Mice is Associated with Cognitive Dysfunction	11
Modeling the physiological roles of the heart and kidney in heart failure with preserved ejection fraction during baroreflex activation therapy	10
Novel endothelial-specific adhesion molecule deficiency influences on pulmonary vascular function potentially contributing to cardiovascular disease progression	10
Hemodynamic response of the aortic valve during dobutamine onset then progressive aortic banding	10
High-throughput methods for cardiac cellular electrophysiology studies: the road to personalized medicine	10
Regenerative cross talk between cardiac cells and macrophages	10
High-impact opportunities to address ischemia: a focus on heart and circulatory research	10
Unlocking the dark matter: noncoding RNAs and RNA modifications in cardiac aging	10
Noninvasive analysis of contractility during identical maturations revealed two phenotypes in ventricular but not in atrial iPSC-CM	10
The cardiovascular subtleties of testosterone on gender-affirming hormone therapy	10
Aging models make waves: predicting vascular aging in virtual patients	10
Comprehensive echocardiographic protocol for pigs with emphasis on diastolic function: advantages over MRI assessment	10
Corrigendum for Nawaito et al., volume 316, 2019, p. H1281–H1296	10
Development of a framework for the hemodynamic impact of positive end-expiratory pressure in normal and heart failure conditions	10
Effects of dietary soy content on cerebral artery function and behavior in ovariectomized female mice	10
Efficacy of a growth hormone-releasing hormone agonist in a murine model of cardiometabolic heart failure with preserved ejection fraction	10
Sleep disturbance and sympathetic neural reactivity in postmenopausal females	10
Increased length-dependent activation of human engineered heart tissue after chronic α1A-adrenergic agonist treatment: testing a novel heart failure therapy	10
Hippo signaling pathway and mitochondrial dysfunction in Takotsubo syndrome	10
Clinical applications for lipid mediators in STEMI	10
Chronic diastolic stretch unmasks conduction defects in an in vitro model of arrhythmogenic cardiomyopathy	10
Corrigendum for Wright et al., volume 320, 2021, p. H923–H941	10
Corrigendum for Skyschally et al., volume 315, 2018, p. H159–H172	10
MEK1-ERK1/2 signaling regulates the cardiomyocyte non-sarcomeric actin cytoskeletal network	10
Childhood household dysfunction is associated with reduced left ventricular mass in young adulthood	10
Supporting and promoting Black physiologists: how can the APS help?	10
A guide to establishing, implementing, and optimizing diversity, equity, inclusion, and accessibility (DEIA) committees	10
Increasing myocardial edema is associated with greater microvascular obstruction in ST-segment elevation myocardial infarction	10
Cerebral sympatholysis: experiments on in vivo cerebrovascular regulation and ex vivo cerebral vasomotor control	9
Arterial stiffness preceding metabolic syndrome in 3,862 adolescents: a mediation and temporal causal longitudinal birth cohort study	9
A practical guide to graduate school interviewing for historically excluded individuals	9
Estrogen contributes to the sex difference in the occurrence of senescence-related T cells during the development of visceral adipose tissue inflammation	9
Multiomics uncover the proinflammatory role of Trpm4 deletion after myocardial infarction in mice	9
Interpretation of field and LEAP potentials recorded from cardiomyocyte monolayers	9
Adult human cardiomyocyte mechanics in osteogenesis imperfecta	9
Implications for neutrophils in cardiac arrhythmias	9
Fine tuning contractility: atrial sarcomere function in health and disease	9
Cardiac fibroblasts: answering the call	9
Long-term circadian disruption shortens life span and dampens blood pressure diurnal rhythms in stroke-prone spontaneously hypertensive rats	9
A cell atlas of thoracic aortic perivascular adipose tissue: a focus on mechanotransducers	9
Chronotype and metabolic syndrome in midlife: findings from the Northern Finland Birth Cohort 1966	9
Acute partial sleep deprivation attenuates blood pressure responses to cycling exercise	9
Chemerin is resident to vascular tunicas and contributes to vascular tone	9
Short-term vascular responses to spring and fall daylight savings time shifts	9
S100A1’s single cysteine is an indispensable redox switch for the protection against diastolic calcium waves in cardiomyocytes	9
Is there an “athlete’s vein”?	9
Seeking clarity on sex differences in cardiovascular complications of Down syndrome	9
Sensitivity and activation of endoplasmic reticulum stress response and apoptosis in the perinatal sheep heart	9
Cardiac function, structural, and electrical remodeling by microgravity exposure	9
Fetal cardiac troponin I levels decline toward birth in sheep	9
Improving rigor and reproducibility in cardiovascular research	9
Longitudinal decline in peak V̇o2 with aging in a healthy population is associated with a reduction in peripheral oxygen utilization but not in cardiac output	9