American Journal of Physiology-Cell Physiology

Papers
(The TQCC of American Journal of Physiology-Cell Physiology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Compositional changes of the lung extracellular matrix in acute respiratory distress syndrome286
Transient Angiotensin Converting Enzyme Inhibition Confers Sex-Specific Protection Against Angiotensin II-Induced Cardiac Remodeling104
Dysregulation of synaptic transcripts underlies network abnormalities in ALS patient-derived motor neurons101
Time-of-day effects on ex vivo muscle contractility following short-term satellite cell ablation88
Role of TGF-β/SMAD/YAP/TAZ signaling in skeletal muscle fibrosis88
STIM1 and lipid interactions at ER-PM contact sites84
The intersection of metformin and inflammation73
Mitochondria-cytokine crosstalk following skeletal muscle injury and disuse: a mini-review62
Recent Advances in Synthetic Notch Receptors for Biomedical Application61
Abnormal purine metabolism in nasal epithelial cells affects allergic rhinitis by regulating Th17/Treg cells59
Activation of the alternative complement pathway modulates inflammation in thoracic aortic aneurysm/dissection59
Potential of synergist ablation to study mechanisms of skeletal muscle hypertrophy in rodent disease models56
The molecular circadian clock of eosinophils: A potential therapeutic target for asthma55
Exogenous ketone esters as a potential therapeutic for treatment of sarcopenic obesity54
Modulating endothelial cell dynamics in fat grafting: the impact of DLL4 siRNA via adipose stem cell extracellular vesicles52
Extracellular cysteines C226 and C232 mediate hydrogen sulfide-dependent inhibition of Orai3-mediated store-operated calcium entry51
Squamous cell carcinoma of the tongue: subtypes and morphological features affecting prognosis49
Focal adhesions, reticular adhesions, flat clathrin lattices: what divides them, what unites them?49
Does force depression resulting from shortening against series elasticity contribute to the activation dependence of optimum length?49
dEREGulated pathways: unraveling the role of epiregulin in skin, kidney, and lung fibrosis48
HOXA3 activates USP15 to suppress autophagy and promote M2-type macrophage polarization in renal cell carcinoma via facilitating the deubiquitination of SQSTM148
p300 maintains primordial follicle activation by repressing VEGFA transcription45
METTL14 promotes ferroptosis in smooth muscle cells during thoracic aortic aneurysm by stabilizing the m6A modification of ACSL445
Hippo cell signaling and HS-proteoglycans regulate tissue form and function, age-dependent maturation, extracellular matrix remodeling, and repair44
Rab7-regulated ferroptosis contributes to tubular epithelial cells injury by degradation of GPX4 via chaperone-mediated autophagy in AKI44
O-GlcNAcylation regulates tyrosine hydroxylase serine 40 phosphorylation and l-DOPA levels42
Microbiota protect against frailty and loss of skeletal muscle, and maintain inflammatory tone during aging in mice41
Body composition alterations in patients with lung cancer41
Inflammation-induced PFKFB3-mediated glycolysis promoting myometrium contraction through the PI3K-Akt-mTOR pathway in preterm birth mice41
LncRNA GAS5 inhibits miR-579-3p to activate SIRT1/PGC-1α/Nrf2 signaling pathway to reduce cell pyroptosis in sepsis-associated renal injury38
Lasmiditan Induces Mitochondrial Biogenesis in Primary Mouse Renal Peritubular Endothelial Cells and Augments Wound Healing and Tubular Network Formation38
Immune system activation and cognitive impairment in arterial hypertension36
METTL14 promotes fibroblast-like synoviocytes activation via the LASP1/SRC/AKT axis in rheumatoid arthritis36
Biomimetic microsystems for cardiovascular studies35
Skeletal dysplasia-causing mutations in TRPV4 alter the chondrocyte transcriptomic response to mechanical loading35
Epigenetic regulation and targeting of ECM for cancer therapy35
The GLP-1-mediated gut-kidney cross talk in humans: mechanistic insight34
Functional asymmetry of the urea transporter UT-B in human red blood cells34
Impaired Ca2+ signaling due to hepatic steatosis mediates hepatic insulin resistance in Alström syndrome mice that is reversed by GLP-1 analog treatment33
Molecular nature and physiological role of the mitochondrial calcium uniporter channel32
Hyperfiltration can be detected by transcutaneous assessment of glomerular filtration rate in diabetic obese mice32
Retraction for Su et al., SHP-1 aggravates obesity-related glomerulopathy and palmitic acid-induced podocyte injury via regulating the PI3K/Nrf2/SIRT1 axis32
Loss of glucose-stimulated β-cell Nr4a1 expression impairs insulin secretion and glucose homeostasis31
Inhibition of mitochondrial citrate shuttle alleviates metabolic syndromes induced by high-fat diet31
Global changes to HepG2 cell metabolism in response to galactose treatment31
Recent advances in measuring and understanding the regulation of exercise-mediated protein degradation in skeletal muscle30
Long noncoding RNA lncPostn links TGF-β and p53 signaling pathways to transcriptional regulation of cardiac fibrosis29
Cuproptosis associated cytoskeletal destruction contributes to podocyte injury in chronic kidney disease29
Ubiquitin-driven G protein-coupled receptor inflammatory signaling at the endosome29
Physical effects of 3-D microenvironments on confined cell behaviors29
Short-term metformin ingestion by healthy older adults improves myoblast function29
Effect of the mitochondrial transaminase (GOT2) on membrane potential-sensitive respiration in mitochondria of differentiated C2C12 muscle cells29
Microscopic computed tomography with AI-CNN-powered image analysis: the path to phenotype bleomycin-induced lung injury29
Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice28
Diverse calcium signaling profiles regulate migratory behavior in avascular wound healing and aberrant signal hierarchy occurs early in diabetes28
Strategies to enhance the response of liver cancer to pharmacological treatments28
Inhibition of P110α and P110δ catalytic subunits of PI3 kinase reverses impaired arterial healing after injury in hypercholesterolemic male mice28
Breast cancer-associated skeletal muscle mitochondrial dysfunction and lipid accumulation is reversed by PPARG28
Role of versican in extracellular matrix formation: analysis in 3D culture27
Role of myofiber-specific FoxP1 in pancreatic cancer-induced muscle wasting27
Placental extracellular vesicles from women with severe preeclampsia alter calcium homeostasis in cardiomyocytes: an ex vivo study27
Functionalizing biomaterials to promote neurovascular regeneration following skeletal muscle injury27
IQGAP-2: a novel interacting partner with the human colonic thiamin pyrophosphate transporter27
Sex omission and male bias are still widespread in cell experiments27
Relocation of phosphofructokinases within epithelial cells is a novel event preceding breast cancer recurrence that accurately predicts patient outcomes26
GRK2 promotes activation of lung fibroblast cells and contributes to pathogenesis of pulmonary fibrosis through increasing Smad3 expression26
Electrophysiological analysis of healthy and dystrophic 3-D bioengineered skeletal muscle tissues26
Role of glypican-1 in regulating multiple cellular signaling pathways26
Chloride transport modulators as drug candidates26
Suppression of ventral hippocampal CA1 pyramidal neuronal activities enhances water intake26
Discovery of thymosin β4 as a human exerkine and growth factor26
Changes in plasma concentration of kynurenine following intake of branched-chain amino acids are not caused by alterations in muscle kynurenine metabolism26
Orthograde signal of dihydropyridine receptor increases Ca2+ leakage after repeated contractions in rat fast-twitch muscles in vivo25
Time of day affects MrgD-dependent modulation of cardiomyocyte contractility25
Transcriptional analysis of cancer cachexia: conserved and unique features across preclinical models and biological sex25
Histone deacetylase inhibitors (HDACi) increase expression of KCa2.3 (SK3) in primary microvascular endothelial cells25
Ion channel Piezo1 induces ferroptosis of trabecular meshwork cells: a novel observation in the pathogenesis in primary open angle glaucoma24
The senescence-associated secretory phenotype in ovarian cancer dissemination24
Mitochondrial ion channels in cardiac function24
The atlas of ACE2 expression in fetal and adult human hearts reveals the potential mechanism of heart-injured patients infected with SARS-CoV-224
A rapid degradation of calponin 2 is required for cytokinesis24
Free fatty acid treatment of mouse preimplantation embryos demonstrates contrasting effects of palmitic acid and oleic acid on autophagy24
Bone marrow stromal cells enhance differentiation of acute myeloid leukemia induced by pyrimidine synthesis inhibitors24
Structural and conformational studies of biased agonism through formyl peptide receptors24
Ubiquitin E3 ligase Atrogin-1 protein is regulated via the rapamycin-sensitive mTOR-S6K1 signaling pathway in C2C12 muscle cells24
Caveolin-3 regulates the activity of Ca2+/calmodulin-dependent protein kinase II in C2C12 cells23
Proteolysis: a key post-translational modification regulating proteoglycans23
The convergence of tumor suppressors on the type I interferon pathway in clear cell renal cell carcinoma and its therapeutic implications23
Role of mechanistic target of rapamycin in autophagy and alcohol-associated liver disease23
Protein phosphatase 1 regulates reactive oxygen species-dependent degradation of histone deacetylase 5 by intermittent hypoxia23
Kir6.1 and SUR2B in Cantú syndrome23
Rapid nutrient depletion to below the physiological range by cancer cells cultured in Plasmax23
The steep uphill path leading to ex vivo gene therapy for genodermatoses23
Following Ussing’s legacy: from amphibian models to mammalian kidney and brain22
Ammonium chloride administration prevents training-induced improvements in mitochondrial respiratory function in the soleus muscle of male rats22
COOH-terminal fragment of APP interacts with p62, forms an aggregate, and induces autophagic degradation in Alzheimer’s cell model22
Hypoxia-inducible factor as a bridge between healthy barrier function, wound healing, and fibrosis21
Ion dynamics and the regulation of circadian cellular physiology20
Long noncoding RNA LINC01882 ameliorates aGVHD via skewing CD4+ T cell differentiation toward Treg cells20
Breast cancers co-opt normal mechanisms of tolerance to promote immune evasion and metastasis20
Neurohormonal connections with mitochondria in cardiomyopathy and other diseases20
Chronic obstructive pulmonary disease and the modulation of CFTR by acute exposure to cigarette smoke20
Inwardly rectifying K+ channels 4.1 and 5.1 (Kir4.1/Kir5.1) in the renal distal nephron20
Urokinase-type plasminogen activator negatively regulates α-smooth muscle actin expression via Endo180 and the uPA receptor in corneal fibroblasts19
An increase in force after stretch of diaphragm fibers and myofibrils is accompanied by an increase in sarcomere length nonuniformities and Ca2+ sensitivity19
Bacterial lipopolysaccharide inhibits colonic carrier-mediated uptake of thiamin pyrophosphate: roles for TLR4 receptor and NF-κB/P38/JNK signaling pathway19
Red light-green light: T-cell trafficking in cardiac and vascular inflammation19
Role of proton-activated G protein-coupled receptors in pathophysiology19
Corneal dystrophy mutations R125H and R804H disable SLC4A11 by altering the extracellular pH dependence of the intracellular pK that governs H+(OH) transport19
The European and Japanese eel NaCl cotransporters β exhibit chloride currents and are resistant to thiazide type diuretics19
Proteoglycans in Toll-like receptor responses and innate immunity19
MicroRNA control of the myogenic cell transcriptome and proteome: the role of miR-1619
Regeneration enhancers: a field in development19
Small molecule drugs to improve sarcomere function in those with acquired and inherited myopathies19
Hydrogen sulfide in health and diseases: cross talk with noncoding RNAs18
EphrinB2 drives osteogenic fate of adult cardiac fibroblasts in a calcium influx dependent manner18
Functional maturation of kidney organoid tubules: PIEZO1-mediated Ca2+ signaling18
Differential MMP-14 targeting by biglycan, decorin, fibromodulin, and lumican unraveled by in silico approach18
MiR146a modulates chondrogenesis of bone marrow mesenchymal stem cells by modulating Lsm11 expression18
Sulforaphane attenuates cancer cell-induced atrophy of C2C12 myotubes18
Physiologically relevant culture medium Plasmax improves human placental trophoblast stem cell function18
A simple and effective scaffold for mouse hepatic stellate cell primary culture18
Exploring the role of urinary extracellular vesicles in kidney physiology, aging, and disease progression18
Regulation of the intestinal Na+/H+ exchanger NHE3 by AMP-activated kinase is dependent on phosphorylation of NHE3 at S555 and S56318
Computational modeling of signal transduction networks without kinetic parameters: Petri net approaches17
Normal muscle fiber type distribution is recapitulated in aged ephrin-A3−/− mice that previously lacked most slow myofibers17
Lymphangioleiomyomatosis: a metastatic lung disease17
Mu-opioid receptor alleviated ferroptosis in hepatic ischemia-reperfusion injury via the HIF-1α/KCNQ1OT1 axis17
Special collection on inward rectifying K+ channels17
3-D culture of human lung fibroblasts decreases proliferative and increases extracellular matrix remodeling genes17
MicroRNA-140 is not involved in sepsis-induced muscle atrophy16
Passing the post: roles of posttranslational modifications in the form and function of extracellular matrix16
A biologically validated mathematical model for decoding epithelial apical, basolateral, and paracellular electrical properties16
MicroRNA-30e-3p reduces coronary microembolism-induced cardiomyocyte pyroptosis and inflammation by sequestering HDAC2 from the SMAD7 promoter16
Sel1-like proteins and peptides are the major Oxalobacter formigenes-derived factors stimulating oxalate transport by human intestinal epithelial cells16
ATP functions as a primary alarmin in allergen-induced type 2 immunity16
The exocyst complex is required for the trafficking and delivery of KCa3.1 to the basolateral membrane of polarized epithelia16
Hypoxia as a regulator of tumor stroma and metastasis16
Effects of temperature on action potentials and ion conductances in type II taste-bud cells16
MARCH8 downregulation modulates profibrotic responses including myofibroblast differentiation16
Enteroendocrine Cells Regulate Intestinal Barrier Permeability15
Skeletal muscle wasting: the estrogen side of sexual dimorphism15
Mitochondrial influences on smooth muscle phenotype15
Kynurenine 3-monooxygenase limits de novo NAD+ synthesis through dietary tryptophan in renal proximal tubule epithelial cell models15
PDIA3/ERp57 promotes a matrix-rich secretome that stimulates fibroblast adhesion through CCN215
Getting sweeter: new evidence for glucose transporters in specific cell types of the airway?15
Parental genetic effects on the offspring’s phenotype without transmission of the gene itself—pathophysiology and clinical evidence15
Mast-cell expressed membrane protein-1 is expressed in classical monocytes and alveolar macrophages in idiopathic pulmonary fibrosis and regulates cell chemotaxis, adhesion, and migration in a TGFβ-de15
Effect of exogenous and endogenous ketones on respiratory exchange ratio and glucose metabolism in healthy subjects15
Polyploid tubular cells initiate a TGF-β1 controlled loop that sustains polyploidization and fibrosis after acute kidney injury15
DOCK2 contributes to pulmonary fibrosis by promoting lung fibroblast to myofibroblast transition15
Maintenance of the branched-chain amino acid transporter LAT1 counteracts myotube atrophy following chemotherapy15
Secreted ADAMTS-like proteins as regulators of connective tissue function15
Microglia and bradykinin cross talk in poststroke cognitive impairment in diabetes14
Stretch response of the mechano-gated channel TMEM63A in membrane patches and single cells14
Elastin, arterial mechanics, and stenosis14
Corrigendum for Zhang et al., volume 318, 2020, p. C346–35914
Defining the versican interactome in lung health and disease14
Emodin ameliorates doxorubicin-induced cardiotoxicity by inhibiting ferroptosis through the remodeling of gut microbiota composition14
Corrigendum for VanWinkle PE et al., volume 319, 2020, p. C667–C67414
Corrigendum for Dai M et al., volume 316, 2019, p. C175–C18514
Characterization of the A-type potassium current in murine gastric fundus smooth muscles14
TRPV4 and chloride channels mediate volume sensing in trabecular meshwork cells14
CD47 and thrombospondin-1 regulation of mitochondria, metabolism, and diabetes13
Interleukin 6 mediated activation of the mineralocorticoid receptor in the aldosterone-sensitive distal nephron13
Oxaloacetate regulates complex II respiration in brown fat: dependence on UCP1 expression13
Pathophysiological levels of GDF11 activate Smad2/Smad3 signaling and induce muscle atrophy in human iPSC-derived myocytes13
Deciphering impact of single nucleotide polymorphisms on cotranscriptional modification in CCM gene mRNAs13
V3: an enigmatic isoform of the proteoglycan versican13
Metalloproteinases in dermal homeostasis13
Estradiol deficiency reduces the satellite cell pool by impairing cell cycle progression13
Cellular and molecular contractile function in aged human skeletal muscle is altered by phosphate and acidosis and partially reversed with an ATP analog13
TRPV1 enhances cholecystokinin signaling in primary vagal afferent neurons and mediates the central effects on spontaneous glutamate release in the NTS13
Potential role of endoplasmic reticulum stress in broiler woody breast myopathy13
Biological sex divergence in transcriptomic profiles during the onset of hindlimb unloading-induced atrophy13
miR-19b-3p is associated with a diametric response to resistance exercise in older adults and regulates skeletal muscle anabolism via PTEN inhibition13
Cartilage extracellular matrix-derived matrikines in osteoarthritis13
Mitochondrial stress responses in Duchenne muscular dystrophy: metabolic dysfunction or adaptive reprogramming?13
Chronic edible dosing of Δ9-tetrahydrocannabinol (THC) in nonhuman primates reduces systemic platelet activity and function13
Syndecan-1 in liver pathophysiology13
Mitochondria: an elegant means of partitioning and harnessing energy13
GPR30 alleviated subarachnoid hemorrhage-induced blood-brain barrier dysfunction by activating the PI3K/Akt and Nrf2/HO-1 pathways13
Effects of oral γ-aminobutyric acid intake on muscle regeneration in diabetic mice12
New insights into the cellular and molecular mechanisms of skeletal muscle fatigue: the Marion J. Siegman Award Lectureships12
Exercise entrainment of musculoskeletal connective tissue clocks12
Corrigendum for Gasier HG et al., volume 319, 2020, p. C746–C75612
In dystrophic mdx hindlimb muscles where fibrosis is limited, versican haploinsufficiency transiently improves contractile function without reducing inflammation12
Wasting away: AJP-Cell Physiology initiates thematic reviews on skeletal muscle wasting12
Sex-specific activation of platelet purinergic signaling is key in local cytokine release and phagocytosis in the peritoneal cavity in intra-abdominal sepsis12
Methyltransferase-like 3 facilitates the stem cell properties of esophageal cancer by upregulating patched homolog 1 via N6-methyladenosine methylation12
Potential usages of A-to-I RNA editing patterns as diagnostic biomarkers12
Corrigendum for Tuncay et al., volume 324, 2023, p. C1017–C102712
Histone lactylation-mediated overexpression of RASD2 promotes endometriosis progression via upregulating the SUMOylation of CTPS112
New Year greetings from the Editor-in-Chief of the American Journal of Physiology-Cell Physiology12
Utilizing 13C-Labeled internal standards to advance the analysis of heparan sulfate12
KV7 channels modulate tension and calcium signaling in mouse corpus cavernosum12
Corrigendum for Roche et al., volume 298, 2010, p. C298–C31212
Circadian cardiac NAD+ metabolism, from transcriptional regulation to healthy aging12
Progranulin and EGFR modulate receptor-like tyrosine kinase sorting and stability in mesothelioma cells12
Muscle-tendon cross talk during muscle wasting12
Parkin-mediated mitophagy is a potential treatment for oxaliplatin-induced peripheral neuropathy12
KLF3 impacts insulin sensitivity and glucose uptake in skeletal muscle11
Sex differences in IL-10’s anti-inflammatory function: greater STAT3 activation and stronger inhibition of TNF-α production in male blood leukocytes ex vivo11
The erythroid K-Cl cotransport inhibitor [(dihydroindenyl)oxy]acetic acid blocks erythroid Ca2+-activated K+ channel KCNN411
Polycystin-2 (PC2) is a key determinant of in vitro myogenesis11
Decorin evokes reversible mitochondrial depolarization in carcinoma and vascular endothelial cells11
ROCK1 is a multifunctional factor maintaining the primordial follicle reserve and follicular development in mice11
Dysregulation of TMEM16A impairs oviductal transport of embryos11
The impact of high-fat feeding and parkin overexpression on skeletal muscle mass, mitochondrial respiration, and H2O2 emission11
Proteoglycans: a common portal for SARS-CoV-2 and extracellular vesicle uptake11
Emerging proteoglycans and proteoglycan-targeted therapies in rheumatoid arthritis11
The matricellular protein thrombospondin-1 in lung inflammation and injury11
Animal models of haploinsufficiency revealed the isoform-specific role of GSK-3 in HFD-induced obesity and glucose intolerance11
Muscle plasticity is influenced by renal function and caloric intake through the FGF23-vitamin D axis11
DEPDC1B-mediated USP5 deubiquitination of β-catenin promotes breast cancer metastasis by activating the wnt/β-catenin pathway11
Bioinformatic tools for epitranscriptomics11
The role of biglycan in the healthy and thoracic aneurysmal aorta11
USP35 promotes breast cancer progression by regulating PFK-1 ubiquitination to mediate glycolysis11
Dopamine receptor signaling regulates fibrotic activation of retinal pigmented epithelial cells11
Fibronectin isoforms in skeletal development and associated disorders11
Impaired regenerative capacity contributes to skeletal muscle dysfunction in chronic obstructive pulmonary disease11
Aerobic training increases mitochondrial respiratory capacity in human skeletal muscle stem cells from sedentary individuals11
Coculture with Colon-26 cancer cells decreases the protein synthesis rate and shifts energy metabolism toward glycolysis dominance in C2C12 myotubes11
G-protein tonic inhibition of calcium channels in pancreatic β-cells11
Platelets and tyrosine kinase inhibitors: clinical features, mechanisms of action, and effects on physiology11
Nestin identifies a subpopulation of rat ventricular fibroblasts and participates in cell migration11
Protective roles of adropin in neurological disease10
The SLC38A5/SNAT5 amino acid transporter: from pathophysiology to pro-cancer roles in the tumor microenvironment10
Reduction of intracellular Mg2+ caused by reactive oxygen species in rat ventricular myocytes10
Regulation of mitochondrial calcium uniporter expression and calcium-dependent cell signaling by lncRNA Tug1 in cardiomyocytes10
Modulation of prostaglandin transport activity of SLCO2A1 by annexin A2 and S100A1010
A single-cell CRISPRi platform for characterizing candidate genes relevant to metabolic disorders in human adipocytes10
Roles for epithelial integrin α3β1 in regulation of the microenvironment during normal and pathological tissue remodeling10
Cytoprotective E-WE thrombin reduces disease severity in a murine model of relapsing-remitting multiple sclerosis10
The role of intracellular calcium and Rho kinase pathways in G protein-coupled receptor-mediated contractions of urinary bladder urothelium and lamina propria10
Hemoglobin increases leukocyte adhesion and initiates lung microvascular endothelial activation via Toll-like receptor 4 signaling10
The multifaceted role of aquaporins in physiological cell migration10
Transglutaminases in fibrosis—overview and recent advances10
Cenicriviroc prevents dysregulation of astrocyte/endothelial cross talk induced by ischemia and HIV-1 via inhibiting the NLRP3 inflammasome and pyroptosis10
Combined application of biosponges and an antifibrotic agent for the treatment of volumetric muscle loss10
The role of vasoactive peptides in skin homeostasis—focus on adiponectin and the kallikrein-kinin system10
Excessive sodium chloride ingestion promotes inflammation and kidney fibrosis in aging mice10
Permissive role of vascular endothelium in fibrosis: focus on the kidney10
ALKHB5-demethylated lncRNA SNHG15 promotes myeloma tumorigenicity by increasing chromatin accessibility and recruiting H3K36me3 modifier SETD210
ASP210: a potent oligonucleotide-based inhibitor effective against TKI-resistant CML cells10
Immunoengineering approaches for cytokine therapy9
Engineering fiber anisotropy within natural collagen hydrogels9
A nonolfactory shark adenosine receptor activates CFTR with unique pharmacology and structural features9
Aquaporin water channels as regulators of cell-cell adhesion proteins9
Nascent shifts in renal cellular metabolism, structure, and function due to chronic empagliflozin in prediabetic mice9
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