OOIR: Observatory of International Research

Papers

(The TQCC of Drug Development and Industrial Pharmacy is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Network pharmacology and molecular docking analysis on molecular targets and mechanisms of Huashi Baidu formula in the treatment of COVID-19	150
Selective laser sintering 3D printing – an overview of the technology and pharmaceutical applications	122
Hydroxyapatite as a biomaterial – a gift that keeps on giving	68
The effects of umbilical cord-derived macrophage exosomes loaded with cisplatin on the growth and drug resistance of ovarian cancer cells	58
Effect of lipid and edge activator concentration on development of aceclofenac-loaded transfersomes gel for transdermal application: in vitro and ex vivo skin permeation	52
Macrophage targeting with the novel carbopol-based miltefosine-loaded transfersomal gel for the treatment of cutaneous leishmaniasis: in vitro and in vivo analyses	46
Inkjet printing of a thermolabile model drug onto FDM-printed substrates: formulation and evaluation	37
Electrospun metronidazole-loaded nanofibers for vaginal drug delivery	37
3D printing for enhanced drug delivery: current state-of-the-art and challenges	35
Emulgel: an effective drug delivery system	35
Medical application of biomimetic 4D printing	35
Synthesis of PEG-4000-co-poly (AMPS) nanogels by cross-linking polymerization as highly responsive networks for enhancement in meloxicam solubility	35
Preparation and evaluation of inhalable dry powder containing glucosamine-conjugated gefitinib SLNs for lung cancer therapy	35
Microneedle ocular patch: fabrication, characterization, and ex-vivo evaluation using pilocarpine as model drug	32
Niosomal delivery of simvastatin to MDA-MB-231 cancer cells	31
Preparation and characterization of polypills containing aspirin and simvastatin using 3D printing technology for the prevention of cardiovascular diseases	30
Bridging the gap: academia, industry and FDA convergence for nanomaterials	27
Stereolithography 3D printing technology in pharmaceuticals: a review	27
Synergistic Effect of Self-Assembled Curcumin and Piperine Co-Loaded Human Serum Albumin Nanoparticles on Suppressing Cancer Cells	27
Glycyrrhizic acid-based self-assembled micelles for improving oral bioavailability of paeoniflorin	26
Formulation of pluronic F127/TPGS mixed micelles to improve the oral absorption of glycyrrhizic acid	26
Augmented healing of full thickness chronic excision wound by rosmarinic acid loaded chitosan encapsulated graphene nanopockets	24
Development and machine-learning optimization of mucoadhesive nanostructured lipid carriers loaded with fluconazole for treatment of oral candidiasis	24
Systematic development and characterization of curcumin-loaded nanogel for topical application	23
New resveratrol micelle formulation for ocular delivery: characterization and in vitro/in vivo evaluation	23

Docetaxel/dimethyl-β-cyclodextrin inclusion complexes: preparation, in vitro evaluation and physicochemical characterization	22
3D printing of immediate-release tablets containing olanzapine by filaments extrusion	21
PEGylated drug delivery systems in the pharmaceutical field: past, present and future perspective	20
Pharmaceutical cocrystal: a game changing approach for the administration of old drugs in new crystalline form	20
Levofloxacin-loaded naturally occurring monoterpene-based nanoemulgel: a feasible efficient system to circumvent MRSA ocular infections	20
Grape seed extract-soluplus dispersion and its antioxidant activity	20
Development of food grade 3D printable ink based on pectin containing cannabidiol/cyclodextrin inclusion complexes	20
Novel approaches to cancer therapy with ibuprofen-loaded Eudragit^® RS 100 and/or octadecylamine-modified PLGA nanoparticles by assessment of their effects on apoptosis	19
Surfactant-free amorphous solid dispersion with high dissolution for bioavailability enhancement of hydrophobic drugs: a case of quercetin	18
Potential alternatives to current cholinesterase inhibitors: anin silicodrug repurposing approach	18
A mechanistic review on the dissolution phase behavior and supersaturation stabilization of amorphous solid dispersions	18
A novel multi-stimuli-responsive theranostic nanomedicine based on Fe₃O₄@Au nanoparticles against cancer	17
Extemporaneous printing of diclofenac orodispersible films for pediatrics	17
Ternary solid dispersions: classification and formulation considerations	17
Dual loading of Nigella sativa oil-atorvastatin in chitosan–carboxymethyl cellulose nanogel as a transdermal delivery system	17
Preparation, characterization, and in vivo evaluation of perphenazine-loaded nanostructured lipid carriers for oral bioavailability improvement	16
Development, validation and application of physiologically based biopharmaceutics model to justify the change in dissolution specifications for DRL ABC extended release tablets	16
Formulation of chitosan coated nanoliposomes for the oral delivery of colistin sulfate: in vitro characterization, ^99mTc-radiolabeling and in vivo biodistribution studies	15
Cocrystallization with syringic acid presents a new opportunity for effectively reducing the hepatotoxicity of isoniazid	15
Development and evaluation of puerarin-loaded controlled release nanostructured lipid carries by central composite design	15
Diclofenac diethylamine nanosystems-loaded bigels for topical delivery: development, rheological characterization, and release studies	15
Chemical composition and pharmacological mechanism of shenfu decoction in the treatment of novel coronaviruspneumonia(COVID-19)	15
Carbamazepine and levetiracetam-loaded PLGA nanoparticles prepared by nanoprecipitation method: in vitro and in vivo studies	15
A review of stimuli-responsive polymeric micelles for tumor-targeted delivery of curcumin	15
3D printing of PVA capsular devices for modified drug delivery: design and in vitro dissolution studies	15
Preparation, evaluation, and in vitro cytotoxicity studies of artesunate-loaded glycyrrhetinic acid decorated PEG-PLGA nanoparticles	14
Turmeric/oregano formulations for treatment of diabetic ulcer wounds	14
Colon-specific tablets containing 5-fluorouracil microsponges for colon cancer targeting	14
Mixed micelles for enhanced oral bioavailability and hypolipidemic effect of liquiritin: preparation, in vitro and in vivo evaluation	14
Development and characterization of orodispersible film containing cefixime trihydrate	14
Preparation and in vitro characterization of rosuvastatin calcium incorporated methyl beta cyclodextrin and Captisol^® inclusion complexes	14
Desirability function approach for development of a thermosensitive and bioadhesive nanotransfersome–hydrogel hybrid system for enhanced skin bioavailability and antibacterial activity of cephalexin	14
Formulation development of paracetamol instant jelly for pediatric use	14
Development of probiotic orodispersible tablets using mucoadhesive polymers for buccal mucoadhesion	14
Antioxidant and antimicrobial activity of red propolis embedded mesoporous silica nanoparticles	14
Filgrastim loading in PLGA and SLN nanoparticulate system: a bioinformatics approach	13
Comparison of media milling and microfluidization methods for engineering of nanocrystals: a case study	13
Formulation of Curcumin-β-cyclodextrin-polyvinylpyrrolidone supramolecular inclusion complex: experimental, molecular docking, and preclinical anti-inflammatory assessment	13
Effect of binary combinations of solvent systems on permeability profiling of pure agomelatine across rat skin: a comparative study with statistically optimized polymeric nanoparticles	13
Proniosomes as a carrier system for transdermal delivery of clozapine	13
Development and evaluation of polymeric micelle containing tablet formulation for poorly water-soluble drug: tamoxifen citrate	12
An updated review of mesoporous carbon as a novel drug delivery system	12
A key role by polymers in microneedle technology: a new era	12
UHPLC-MS phytochemical profiling, biological propensities and in-silico studies of Alhagi maurorum roots: a medicinal herb with multifunctional properties	12
Impact of bile salts and a medium chain fatty acid on the physical properties of self-emulsifying drug delivery systems	12
Development of novel biopolymer-based nanoparticles loaded cream for potential treatment of topical fungal infections	12
Preparation, statistical optimization, in vitro characterization, and in vivo pharmacological evaluation of solid lipid nanoparticles encapsulating propolis flavonoids: a novel treatment	12
Fabrication and optimization of amoxicillin-loaded niosomes: an appropriate strategy to increase antimicrobial and anti-biofilm effects against multidrug-resistant Staphylococcus aureus strains	12
Development of orally administered insulin-loaded polymeric-oligonucleotide nanoparticles: statistical optimization and physicochemical characterization	12
Intranasal drug delivery of sumatriptan succinate-loaded polymeric solid lipid nanoparticles for brain targeting	12

Improving gallic acid and quercetin bioavailability by polymeric nanoparticle formulation	11
Evaluation of powder-layering vs. spray-coating techniques in the manufacturing of a swellable/erodible pulsatile delivery system	11
A rutin nanocrystal gel as an effective dermal delivery system for enhanced anti-photoaging application	11
Prolonged distribution of aerosolized PEGylated liposomes in the lungs of mice with bleomycin-induced pulmonary fibrosis	11
Odorranalectin modified PEG–PLGA/PEG–PBLG curcumin-loaded nanoparticle for intranasal administration	11
Carbopol-olive oil-based bigel drug delivery system of doxycycline hyclate for the treatment of acne	10
Investigating the influences of intermolecular interactions on viscoelastic performance of pressure-sensitive adhesive by FT–IR spectroscopy and molecular modeling	10
Enhancement of oral bioavailability of drugs using lipid-based carriers: a meta-analysis study	10
Enhancement of loading and oral bioavailability of curcumin loaded self-microemulsifying lipid carriers usingCurcumaoleoresins	10
Development and optimization of tibezonium iodide and lignocaine hydrochloride containing novel mucoadhesive buccal tablets: a pharmacokinetic investigation among healthy humans	10
Microneedle system: a modulated approach for penetration enhancement	10
Calcium alginate nanoparticle crosslinked phosphorylated polyallylamine to the controlled release of clindamycin for osteomyelitis treatment	10
Colon targeted dosage form of Capecitabine using folic acid anchored modified carbon nanotube: in vitro cytotoxicity, apoptosis and in vivo roentgenographic study	10
Development and evaluation of proniosomes to enhance the transdermal delivery of cilostazole and to ensure the safety of its application	10
Improved hepatoprotective activity of Beta vulgaris L. leaf extract loaded self-nanoemulsifying drug delivery system (SNEDDS): in vitro and in vivo evaluation	9
Emerging theranostics to combat cancer: a perspective on metal-based nanomaterials	9
Electrostatic deposition assisted preparation, characterization and evaluation of chrysin liposomes for breast cancer treatment	9
Development and evaluation of tofacitinib transdermal system for the treatment of rheumatoid arthritis in rats	9
Amorphous nano morin outperforms native molecule in anticancer activity and oral bioavailability	9
An examination of carbopol hydrogel/organogel bigels of thymoquinone prepared by microwave irradiation method	9
A novel combination of Soluplus^®/Poloxamer for Meloxicam solid dispersions via hot melt extrusion for rapid onset of action. Part 2: comparative bioavailability and IVIVC	9
Development and optimization of drug-loaded nanoemulsion system by phase inversion temperature (PIT) method using Box–Behnken design	9
Functional vinorelbine plus schisandrin B liposomes destroying tumor metastasis in treatment of gastric cancer	9
Lyophilized SLN of Cinnacalcet HCl: BBD enabled optimization, characterization and pharmacokinetic study	9
Residence time and mixing capacity of a rotary tablet press feed frame	9
Improved pharmaceutical properties of ritonavir through co-crystallization approach with liquid-assisted grinding method	9
PEGylated solid lipid nanoparticles functionalized by aptamer for targeted delivery of docetaxel in mice bearing C26 tumor	9
Analytical method development, validation and forced degradation studies for rutin, quercetin, curcumin, and piperine by RP-UFLC method	9
Statistical development and in vivo evaluation of resveratrol-loaded topical gel containing deformable vesicles for a significant reduction in photo-induced skin aging and oxidative stress	9
In-use stability studies: guidelines and challenges	9
Intranasal delivery of a nicotine vaccine candidate induces antibodies in mouse blood and lung mucosal secretions that specifically neutralize nicotine	8
In vitro and in vivo evaluation of taste-masked orodispersible tablets of fluoxetine hydrochloride for the treatment of depression	8
Development of polymeric nanoparticle gel prepared with the combination of ionic pre-gelation and polyelectrolyte complexation as a novel drug delivery of timolol maleate	8
Formulation and performance evaluation of polymeric mixed micelles encapsulated with baicalein for breast cancer treatment	8
BCS class II drug loaded protein nanoparticles with enhanced oral bioavailability:in vitroevaluation andin vivopharmacokinetic study in rats	8
Microneedle-assisted transdermal delivery of amlodipine besylate loaded nanoparticles	8
Formulation and evaluation of interpenetrating polymeric network for controlled drug delivery	8
Comparative study of novel green UV-spectrophotometric platforms for simultaneous rapid analysis of flumethasone pivalate and clioquinol in their combined formulation	8
Nanostructured lipid carrier-mediated lung targeted drug delivery system to enhance the safety and bioavailability of clofazimine	8
Preparation, characterization, and pharmacodynamic study on deep second degree burns of total flavonoids composite phospholipids liposome gel of Oxytropis falcata Bunge	8
Pharmacokinetics and brain distribution studies of perphenazine-loaded solid lipid nanoparticles	8
Intranasal galantamine/chitosan complex nanoparticles elicit neuroprotection potentials in rat brains via antioxidant effect	8
Extraction of triterpenoid compounds from Ganoderma Lucidum spore powder through a dual-mode sonication process	8
Enhanced oral bioavailability of self-assembling curcumin–vitamin E prodrug-nanoparticles by co-nanoprecipitation with vitamin E TPGS	8
GGP modified daunorubicin plus dioscin liposomes inhibit breast cancer by suppressing epithelial–mesenchymal transition	8
Amelioration of physicochemical, pharmaceutical, and pharmacokinetic properties of lornoxicam by cocrystallization with a novel coformer	8
Antihyperuricemic efficacy of Scopoletin-loaded Soluplus micelles in yeast extract/potassium oxonate-induced hyperuricemic mice	8
Validated specific HPLC-DAD method for simultaneous estimation of paracetamol and chlorzoxazone in the presence of five of their degradation products and toxic impurities	8
Fabrication and characterization of dissolving microneedles for transdermal drug delivery of allopurinol	7
Design and optimization of a probiotic tablet for gastrointestinal tolerance by a simplex-centroid mixture	7
Vision of bacterial ghosts as drug carriers mandates accepting the effect of cell membrane on drug loading	7
Galantamine transdermal patch shows higher tolerability over oral galantamine in rheumatoid arthritis rat model	7
Development and characterization of ibuprofen co-crystals granules prepared via fluidized bed granulation in a one-step process – a design of experiment approach	7
Smart UV-spectrophotometric platforms for rapid green analysis of miconazole nitrate and nystatin in their combined suppositories and in vitro dissolution testing	7
Raloxifene HCl – quercetin co-amorphous system: preparation, characterization, and investigation of its behavior in phosphate buffer	7
Empagliflozin containing chitosan-alginate nanoparticles in orodispersible film: preparation, characterization, pharmacokinetic evaluation and itsin-vitroanticancer activity	7
Monoolein-based nanoparticles containing indinavir: a taste-masked drug delivery system	7
Formulation design and optimization of cationic-charged liposomes of brimonidine tartrate for effective ocular drug delivery by design of experiment (DoE) approach	7
Investigation of the mucoadhesivity, swelling, and drug release mechanisms of indomethacin buccal tablets: effect of formulation variables	7
Study on the mechanism of treating COVID-19 with Shenqi Wan based on network pharmacology	7
Development of UV–visible spectrophotometric methods for the quantitative andin silicostudies for cilazapril optimized by response surface methodology	7
Application of HPMC HME polymer as hot melt extrusion carrier in carbamazepine solid dispersion	7
Reckoning γ-Glutamyl-S-allylcysteine as a potential main protease (m^pro) inhibitor of novel SARS-CoV-2 virus identified using docking and molecular dynamics simulation	7
Preparation, characterization and in-Vitro/in-Vivo evaluation of meloxicam extruded pellets with enhanced bioavailability and stability	7