OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Toxicological Sciences is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Glasgow coma scale may be a predictive factor for delayed neurological sequelae after carbon monoxide poisoning: a retrospective analysis of a nationwide multicenter observational registry in Japan	15
Long-term exposure to urban particulate matter exacerbates mortality after ischemic stroke in mice	14
Histological differences between the central and peripheral areas of the testes of busulfan-administered mice	13
Per- and polyfluoroalkyl substances: toxicokinetics, exposure and health risks	13
An exploratory study of sex differences in thallium-induced nephrotoxicity in rats	11
Neurotoxicity of acrylamide in wild-type and TNF-α depletion mice: possible alternative role of IL-6 and dipolar effects of TNF-α depletion on oxidative stress pathway	10
Characterization of the toxicological findings from 90-day and 2-year repeated-dose toxicity studies of pesticides in rats	10
Neuro-protective effects of n-butylphthalide on carbon monoxide poisoning rats by modulating IL-2, AKT and BCL-2	10
Variation and classification of chemically-induced zebrafish malformations for the ICH S5 (R3) guideline: an atlas for zebrafish teratogenesis	9
Identification of postmortem product of amlodipine decomposition by hemoglobin with LC-Q-Orbitrap-MS	9
A preliminary evaluation of the applicability of the <i>in vitro</i> to <i>in vivo</i> extrapolation approach to quantitative risk assessment	9
Activation of the arylhydrocarbon receptor through maternal beta-naphthoflavone exposure in the neonatal kidney	9
Human gut microbiota influences drug-metabolizing enzyme hepatic Cyp3a: A human flora-associated mice study	9
Diphenylarsinic acid induced astrocyte-preferential cell-type-specific aberrant activation of signal transduction related to oxidative stress, MAP kinase activation, transcription factor regulation, a	9
Oxidative stress-induced TET1 upregulation mediates active DNA demethylation in human gastric epithelial cells	8
Considerations for infection risks identified in target safety review	8
<i>In vivo</i> analysis of acute eletropharmacological effects of proton pump inhibitors using halothane-anesthetized dogs: a translational study of cardiovascular adverse events	8
Protective effects of retinoic acid on cadmium toxicity in human proximal tubular epithelial cells	8
Evaluation of circulating miR-216a and miR-217 as biomarkers of pancreatic damage in the L-arginine-induced acute pancreatitis mouse model	8
Oxycodone alleviates LPS-induced neuroinflammation by regulating the CREB/miR-181c/PDCD4 axis	7
Male rat-specific fatty change in liver by DS-1971a: Elevation in phospholipids and adenosine as early responses to the fatty change in male rat-derived primary hepatocytes	7
Methylthioacetic acid, a derivative of aroma compounds from <i>Cucumis melo</i> var. <i>conomon</i> dose-dependently triggers differentiation and apoptosis of RCM-1 human color	7
Comparison of the acceptable surface limits derived from the skin sensitization potency for workers and swab residue limits determined from the permitted daily exposure derived from the systemic effec	7
Quantitative analysis of Cyp1a2 expression and temporal characterization of zonation structure formation during mouse liver development	6
Comprehensive molecular docking on the AlphaFold-predicted protein structure proteome: identifying target protein candidates for puberulic acid	6

Anticancer agent doxorubicin toxicity to <i>in vitro X. laevis</i> tadpole organ heart and mature frog heart and liver mitochondria	6
Dabrafenib stimulates autophagy in thyroid carcinoma cells via HMGB-1	6
Dihydropyrazine activates the CAMKK2-AMPK-ULK1 signaling pathway in human hepatoma HepG2 cells	5
Carcinogenicity and chronic toxicity of butyl methacrylate in rats and mice by a two-year inhalation study	5
Amelioration of lipopolysaccharides-induced impairment of fear memory acquisition by alpha-glycosyl isoquercitrin through suppression of neuroinflammation in rats	5
Potential of connexin 32 as a predictive marker for drug-induced cholestatic liver injury in a collagen vitrigel-culture model of HepG2-NIAS cells, a new subline of HepG2 cells, with bile canaliculus-	5
Melatonin therapy reverses lead exposure-induced testicular damage in rats despite the lack of effect on serum testosterone levels	5
Establishment of hyperoxic cell culture system for predicting drug-induced liver injury: reducing accumulated lipids in hepatocytes derived from chimeric mice with humanized liver	5
Prevention of prolactin reduction: a novel strategy countering multi-generational growth retardation caused by maternal exposure to 2,3,7,8-tetrachlorodibenzo-<i>p</i>-dioxin	5
Investigation of additional suitable positive controls in the human Cell Line Activation Test	5
Propofol improves ischemia reperfusion-induced liver fibrosis by regulating lncRNA HOXA11-AS	5
Evaluation of neurotoxicity of anticancer drugs using nematode <i>Caenorhabditis elegans</i> as a model organism	5
<i>Drosophila melanogaster</i> as potential alternative animal model for evaluating acute inhalation toxicity	4
Effects of microsampling on toxicity evaluation of 1-naphthylisothiocyanate (ANIT), a hepatotoxic substance, in a mouse toxicity study	4
Nafamostat mesylate sensitizes ovarian cancer cells to carboplatin by promoting the ZNF24-mediated inhibition of WNT2B	4
Successful multimodal treatment of venlafaxine overdose-induced catecholamine-refractory shock: a case report	4
Paternal methamphetamine exposure differentially affects first and second generations in mice	4
Differential effects of different time windows of postnatal perfluorooctane sulfonate exposure on cognitive development in mouse hippocampus	4
Plasma membrane damage triggered by benzalkonium chloride and cetylpyridinium chloride induces G<sub>0</sub>/G<sub>1</sub> cell cycle arrest via Cdc6 reduction in human lung ep	4
Induction of systemic inflammation by welding fume exposure in office workers as well as welders in welding factories	4
Transcriptome analysis in various cell lines exposed to nitric oxide	4
Comparative sensitivity of laboratory animals used for preclinical convulsion risk assessment to drug-induced convulsion	4
Toxicological effects of Sb(III), Sb(V), and NMG-Sb(V) in human lung, kidney, and liver cells: cytotoxicity and fibrotic factor induction	4
Lipopolysaccharide administration increases the susceptibility of mitochondrial permeability transition pore opening via altering adenine nucleotide translocase conformation in the mouse liver	4
Effects of food restriction on toxicological parameters in juvenile rats	4
Comparative study of susceptibility to methylmercury cytotoxicity in cell types composing rat peripheral nerves: a higher susceptibility of dorsal root ganglion neurons	4
Optimisation of Photo-KeratinoSens™ for <i>in vitro</i> photoallergenicity assessment	4
Impact of selenium content in fetal bovine serum on ferroptosis susceptibility and selenoprotein expression in cultured cells	4