Experimental Gerontology

Article	Citations
Age-related structural changes show that loss of fibers is not a significant contributor to muscle atrophy in old mice	183
Editorial Board	147
Long-term administration of soft drink causes memory impairment and oxidative damage in adult and middle-aged rats	120
Effect of intermittent hypoxic conditioning on inflammatory biomarkers in older adults	95
Overexpression of solute carrier family 6 member 12 promotes cell injury in Parkinson's disease via MAPK signaling pathway	85
Corrigendum to “Segmental extracellular-to-intracellular water resistance ratio and physical function in older adults” [Exp. Gerontol. 181 (2023) 112278]	74
Anti-fibrosis effect and its mechanism of atractylenolide III on post-traumatic extending knee joint contracture in rats	72
Comparison of metabolic risk factors, physical performances, and prevalence of low back pain among categories determined by visceral adipose tissue and trunk skeletal muscle mass in middle-aged men	70
Sleep problems and mild cognitive impairment among adults aged ≥50 years from low- and middle-income countries	70
The association between cardiovascular risk factors and major cardiovascular diseases decreases with increasing frailty levels in geriatric outpatients	68
Impact of repetitive home-based galvanic vestibular stimulation on cognitive skills in healthy older adults	67
Receiving financial support and its association with late-age depression: The mediating role of social engagement	63
Oral frailty as a risk factor for mild cognitive impairment in community-dwelling older adults: Kashiwa study	59
Editorial Board	59
Activation of α7nAChR by PNU282987 improves cognitive impairment through inhibiting oxidative stress and neuroinflammation in D-galactose induced aging via regulating α7nAChR/Nrf2/HO-1 signaling pathw	57
Senior Fitness Test in the assessment of the physical fitness of people with Parkinson's disease	55
High-intensity interval training reduces the induction of neutrophil extracellular traps in older men using live-neutrophil imaging as biosensor	55
Neutrophil-lymphocyte ratio as a predictor of slow gait speed in older adults: The Rugao Longitudinal Aging Study	51
Correlation between blood pressure and mortality in older critically ill patients: Insights from a large intensive care unit database	49
Immunophenotypic characterization of B1a lymphocytes in Cuban older adults	49
Cytomegalovirus and herpes simplex type 1 infections and immunological profile of community-dwelling older adults	48
The effect of tamoxifen on the lipid profile in women: A systematic review and meta-analysis of randomized controlled trials	45
Segmental extracellular-to-intracellular water resistance ratio and physical function in older adults	45
Oral administration of liposome-encapsulated thymol could alleviate the inflammatory parameters in serum and hippocampus in a rat model of Alzheimer's disease	45
Aerobic exercise attenuates abnormal myelination and oligodendrocyte differentiation in 3xTg-AD mice	44

Systematic review on the effects of physical exercise on cellular immunosenescence-related markers – An update	43
Senolytic agents lessen the severity of abdominal aortic aneurysm in aged mice	42
Comparative efficacy of exercise interventions for cognitive health in older adults: A network meta-analysis	41
Muscle weakness is a prognostic indicator of disability and chronic disease multimorbidity	41
Enhancing fracture risk indication: The impact of bone load index and muscle fat infiltration on vertebral compression fracture	41
A pilot investigation of reliability and validity of balance and gait assessments using telehealth with healthy older adults	41
Gait speed reference values in community-dwelling older adults – Cross-sectional analysis from the Rotterdam Study	40
Effects of an inulin fiber diet on the gut microbiome, colon, and inflammatory biomarkers in aged mice	39
The pleiotropic beneficial intervention of olive oil intake on the Alzheimer's disease onset via fibrinolytic system	39
MicroRNA-139-5p inhibits vascular endothelial cell viability and serves as a diagnostic biomarker in acute myocardial infarction patients	39
Frequency and factors associated with sarcopenia prediction in adult and elderly patients hospitalized for COVID-19	39
The biological roots of the sex-frailty paradox	38
Inflammatory biomarkers of frailty: A review	38
The inflammatory profiling in a cohort of older patients suffering from cognitive decline and dementia	38
Exosomes: A promising therapeutic strategy for intervertebral disc degeneration	37
Editorial Board	37
Parental age at death is associated with age at first birth in offspring	34
QKL injection ameliorates Alzheimer's disease-like pathology by regulating expression of RAGE	34
Editorial Board	34
Effects of fasting on skeletal muscles and body fat of adult and old C57BL/6J mice	34
Development and validation of a risk prediction model for frailty in older nappers	33
Metformin use and brain atrophy in nondemented elderly individuals with diabetes	33
The promise of amplification assays for accurate early detection of α-synucleinopathies: A review	33
The influence of a 16-week exercise program, APOE status, and age on executive function task performance: A randomized trial	32
A VO2peak prediction model in older adults' patients with Parkinson's disease	32
Aging & COVID-19 susceptibility, disease severity, and clinical outcomes: The role of entangled risk factors	32
Associations between the timing of eating and weight-loss in calorically restricted healthy adults: Findings from the CALERIE study	32
Determinants of instrumented sedentary and physical activity behavior in geriatric rehabilitation inpatients: RESORT	32
Voluntarily wheel running inhibits the growth of CRPC xenograft by inhibiting HMGB1 in mice	31
Comparative evaluation of inflammatory parameters and substitute insulin resistance indices in elderly women with and without type 2 diabetes mellitus	31
Forecasting prevalence and mortality of Alzheimer's disease using the partitioning models	31
Study on correlation between perioperative cognitive function and nutritional status in elderly patients with gastric cancer	31
Relationship between serum uric acid and sarcopenia in geriatric heart failure patients with preserved ejection fraction	31
Identifying and validating the key regulatory transcription factor YY1 in the aging process of pancreatic beta cells based on bioinformatics	31
Red blood cell distribution width is associated with frailty in older inpatients in China: Sex differences in a cross-sectional study	30
Linear and non-linear analyses of autonomic modulation in uncontrolled and controlled elderly resistant hypertensives	30
Drosophila melanogaster flies better know than us the nutrients they need: Let them choose	30
Neuroprotective effects of short-chain fatty acids in MPTP induced mice model of Parkinson's disease	29
Alzheimer's disease genes and proteins associated with resistance and aerobic training: An in silico analysis	29
Effects of home-based specific and comprehensive balance-training programs on balance and functional status in healthy older adults	29
Age-specific in the relationship between diastolic blood pressure and the risk of cardiovascular disease: A cohort study of the UK Biobank	29
Development and evaluation studies of Corylin loaded nanostructured lipid carriers gel for topical treatment of UV-induced skin aging	29
Mediterranean diet and mitochondria: New findings	29
The relationship between nutrition and depression in the life process: A mini-review	29
The effects of raloxifene on endothelial function and Inflammation in Postmenopausal women: A Meta-analysis of randomized controlled trials	28
Effects of free versus restricted arm movements on postural control in normal and modified sensory conditions in young and older adults	28
Differences in power and performance during sit-to-stand test and its relationships to functional measures in older adults with and without Parkinson's disease	28
Editorial Board	28
Longitudinal association between cardiometabolic comorbidities and physical activity in middle aged and older adults living with HIV	27
Network-based analysis identifies key regulatory transcription factors involved in skin aging	27

Influence of human gut microbiome on the healthy and the neurodegenerative aging	27
Effects of functional and combined training on subsets of memory T cells and functional fitness of postmenopausal women: A randomized controlled trial	26
Poor sleep quality is associated with probable sarcopenia in community-dwelling older adults: Results from the longevity check-up (lookup) 8+	26
Machine learning insights on activities of daily living disorders in Chinese older adults	25
Bioinformatics identification of potential biomarkers and therapeutic targets for ischemic stroke and vascular dementia	25
Metformin delays the decline in thermogenic function of brown adipose tissue in a mouse model of Hutchinson-Gilford progeria syndrome	25
Effects of 5-aminolevulinic acid with iron supplementation on respiratory responses to graded cycling and interval walking training achievement in older women over 75 yrs	25
Gut microbiome, and immune cells mediated effect on depression: A two-step, two-sample Mendelian randomization analysis	25
Multimodal and conventional resistance training interventions improve muscle function in older adults: Findings from the Training IMCT study	25
Milk kefir therapy improves the skeletal response to resistance exercise in rats submitted to glucocorticoid-induced osteoporosis	24
The role of oxidative stress in the association between metabolic score for insulin resistance and stroke: evidence from two large population-based studies	24
Effects of high-intensity interval training combined with traditional strength or power training on functionality and physical fitness in healthy older men: A randomized controlled trial	24
The effect of vitamin D supplementation on circulating osteoprogenitor cells: A pilot randomized controlled trial	24
PGC-1α participates in regulating mitochondrial function in aged sarcopenia through effects on the Sestrin2-mediated mTORC1 pathway	23
Integration of small needle knife in treating inflammatory factors, Th17 cell function, and magnetic resonance imaging evaluation in osteoporosis complicated by compression fractures in elderly patien	23
MicroRNA-511-3p regulates Aβ1–40 induced decreased cell viability and serves as a candidate biomarker in Alzheimer's disease	23
Polypharmacy, physical activity, and sedentary time in older adults: A scoping review	23
Brainstem auditory evoked potential in cognitive impairment in patients with type 2 diabetes mellitus	23
Validity of the Korean triage and acuity scale in older patients compared to the adult group	23
The effect-modification of physical activity on the association of pain with impaired physical function in aging adults	23
Circulating microRNAs related to lipid metabolism and solid tissue maintenance and morphology associate with mortality in elderly twins	22
The effects of PPARγ inhibitor on bones and bone marrow fat in aged glucocorticoid-treated female rats	22
Differences in mitochondrial function between brain and heart of senile rats exposed to acute hypobaric hypoxia. Role of nitric oxide	22
Deciphering the whale's secrets to have a long life	22
Short-term exposure to a clinical dose of metformin increases skeletal muscle mitochondrial H2O2 emission and production in healthy, older adults: A randomized controlled trial	22
Association between sex steroid hormones and α-klotho: Results from the NHANES 2013-2016 and Mendelian randomization study	22
Exercise training alters resting brain-derived neurotrophic factor concentration in older adults: A systematic review with meta-analysis of randomized-controlled trials	22
MRI characterization of rat brain aging at structural and functional level: Clues for translational applications	22
Spermidine alleviates thymopoiesis defects and aging of the peripheral T-cell population in mice after radiation exposure	22
The characteristics of the body mass frequency index in dysmobility syndrome: A pilot study	21
Editorial Board	21
The relationship between muscle strength and epicardial fat in healthy adults	21
Very old adults show impaired fatigue resistance compared to old adults independently of sex during a knee-extensors isometric test	21
Age- and sex-dependence of muscle quality: Influence of intramuscular non-contractile tissues	21
Visuospatial cognition predicts performance on an obstructed vision obstacle walking task in older adults	21
Extra Virgin Olive Oil consumption from Mild Cognitive Impairment patients attenuates oxidative and nitrative stress reflecting on the reduction of the PARP levels and DNA damage	21
Effect of blood flow restriction combined with low-intensity training on the lower limbs muscle strength and function in older adults: A meta-analysis	21
Are assessment measures for components of the International Classification of Functioning, Disability and Health reproducible for use on pre-frail and frail older adults? A systematic review	21
Sarcopenia is independently associated with parietal atrophy in older adults	20
Age-associated changes in the gut microbiome impact efficacy of tumor immunomodulatory treatments	20
Mechanism associated with changes in male reproductive functions during ageing process	20
The influence of ageism on the hallmarks of aging: Where age stigma and biology collide	20
Brain health correlates of mobility-related confidence	20
Does excess body weight accelerate immune aging?	20
Immunosenescence evaluation of peripheral blood lymphocyte subsets in 957 healthy adults from 20 to 95 years old	20
Active older dancers have lower C-terminal Agrin fragment concentration, better balance and gait performance than sedentary peers	20
Association of leukocyte telomere length with perceived physical fatigability	20
Association between METS-VF and sarcopenia among middle-aged and older adults in China: The first longitudinal evidence from CHARLS	20
Influence of sarcopenia on surgical efficacy and mortality of percutaneous kyphoplasty in the treatment of older adults with osteoporotic thoracolumbar fracture	19
Changes in AMPK activity induces cellular senescence in human dental follicle cells	19
Increased knee-extension strength and steps per day after a novel post-hospitalization rehabilitative program in older adults (65+): Secondary analyses of a randomized controlled single-blinded trial	19
Editorial Board	19
High-intensity interval training reduces blood pressure in older adults: A systematic review and meta-analysis	19
SARC-F predicts poor motor function, quality of life, and prognosis in older patients with cardiovascular disease and cognitive impairment	19
Age-dependent down-regulation of orexin receptors in trigeminal nucleus caudalis correlated with attenuation of orexinergic analgesia in rats	19
Circadian rhythms and objective measures of physical activity among middle-aged and older adults in Taiwan	18
Cross-sectional and prospective associations between homocysteine and a frailty index: A post-hoc analysis of the multidomain Alzheimer's prevention trial (MAPT)	18
Comparing the effects of different exercises on blood pressure and arterial stiffness in postmenopausal women: A systematic review and meta-analysis	18
Association of back pain with major depressive disorder among older adults in six low- and middle-income countries: A cross-sectional study	18
Erythrocyte Zn concentration and antioxidant response after supplementation with Zn in a postmenopausal population. A double-blind randomized trial	18
Mitophagy: At the heart of mitochondrial quality control in cardiac aging and frailty	18
Plasma levels of myokines and inflammatory markers are related with functional and respiratory performance in older adults with COPD and sarcopenia	18
The visual control of locomotion when stepping onto moving surfaces: A comparison of younger and older adults	18
Extended anesthesia exposure for abdominal and pelvic procedures in older adults with colorectal cancer: Associations with chart dementia diagnoses	18
Identification of two patterns of mitochondrial DNA-copy number variation in postcentral gyrus during aging, influenced by body mass index and type 2 diabetes	18
Dietary inflammatory index and its associations with cardiovascular diseases and cancer: Evidence form NHANES 2017–2018 and Mendelian randomization analysis	18
The association of sleep and cortical thickness in mild cognitive impairment	18
The multi-tissue benefits of exercise on aging human physiology	18
The association between low cognitive reserve and subjective memory complaints in functionally independent older women	17
Effect of developmental and adult diet composition on reproductive aging in Drosophila melanogaster	17
Cross-sectional and longitudinal associations of outdoor walking with overall mental health in later life	17
Genetic analysis of comorbidities between osteoarthritis, sarcopenia, and osteoporosis	17
No causal relationship between serum urate and neurodegenerative diseases: A Mendelian randomization study	17
Exploring the impact of interleukins on sarcopenia development: A systematic review and meta-analysis	17
Inflammation and sarcopenia: A focus on circulating inflammatory cytokines	16
Mediterranean diet and structural neuroimaging biomarkers of Alzheimer's and cerebrovascular disease: A systematic review	16
The effect of casein hydrolysate intake on cerebral neural regulation during cognitive tasks in the elderly	16
Effects of a prolonged diet regimen on autophagic function in rat islets with aging	16
Decadal analysis of efficacy and safety profiles of mesenchymal stem cells from varied sources in knee osteoarthritis patients: A systematic review and network meta-analysis	16
Editorial Board	16

The tissue factor expression on CD14++CD16-monocytes is a new markers in the Chinese Han older adult population with sepsis: A prospective study	16
The impact of exercise training on inflammatory markers in postmenopausal women: A systemic review and meta-analysis	16
Old age as a risk factor for liver diseases: Modern therapeutic approaches	16
Kaempferol: Paving the path for advanced treatments in aging-related diseases	16
Corrigendum: “Tectoridin inhibits osteoclastogenesis and bone loss in a murine model of ovariectomy-induced osteoporosis” [Exp. Gerontol. 140: 2020; 111057. DOI:10.1016/j.exger.2020.111057]	16
Environmental enrichment applied with sensory components prevents age-related decline in synaptic dynamics: Evidence from the zebrafish model organism	16
P16INK4a deletion alleviates contrast-induced acute kidney injury by ameliorating renal cell apoptosis and suppressing inflammation and oxidative stress	16
Lack of association between serum myonectin levels and sarcopenia in older Asian adults	16
Association between physical activity & sedentary time on frailty in adults with chronic kidney disease: Cross-sectional NHANES study	16
Experimental models for elderly patients with membranous nephropathy: Application and advancements	16
Editorial Board	16
Anthropometric indicators and cardiovascular diseases risk in pre-diabetic and diabetic adults: NHANES 1999–2018 cross-sectional analysis	16
DPP4 inhibitors as a potential therapeutic option for sarcopenia: A 6-month follow-up study in diabetic older patients	15
S1P lyase inhibition prevents lung injury following high pressure-controlled mechanical ventilation in aging mice	15
Exogenous oxidative stressors elicit differing age and sex effects in Tigriopus californicus	15
Smaller grey matter volume in the central olfactory system in mild cognitive impairment	15
The role of melatonin in sarcopenia: Advances and application prospects	15
Comparison of clinical characteristics and outcome measures of PCR-positive and PCR-negative patients diagnosed as COVID-19: Analyses focusing on the older adults	15
Editorial Board	15
Differences in acute neuromuscular response after single session of resistance exercise between young and older adults	15
Equating conversion norms for the Mini-Mental State Examination and Montreal Cognitive Assessment in healthy subjects and patients with neurodegenerative disorders	15
Peripheral double negative T: A look at senescent Cubans	15
Parkinson's disease and microRNAs - Lessons from model organisms and human studies	15
Performance during reactive handrail grasping during forward walking by young and older adults with and without prior knowledge of the direction of movement is correlated with grip strength	15
Cellular senescence and glaucoma	15
Osteocalcin inhibits myocyte aging through promotion of starvation-induced autophagy via IL-6/STAT3 signaling	15
Editorial Board	14
Thigh muscles are more susceptible to age-related muscle loss when compared to lower leg and pelvic muscles	14
Cognitive–exercise dual-task intervention ameliorates cognitive decline in natural aging rats through reducing oxidative stress and enhancing synaptic plasticity	14
Protective effects of GLHP from Gracilaria lemaneiformis against UVB-induced photodamage in human immortalized keratinocytes cells and BALB/c mice	14
Interaction of Klotho and sirtuins	14
Maresin1 ameliorates postoperative cognitive dysfunction in aged rats by potentially regulating the NF-κB pathway to inhibit astrocyte activation	14
Gender-specific association of SLC19A1 and MTHFR genetic polymorphism with oxidative stress biomarkers and plasma folate levels in older adults	14
Neurobiological and anti-aging benefits of yoga: A comprehensive review of recent advances in non-pharmacological therapy	14
Age related gut microbiota regulates energy-related metabolism to influence natural aging phenotypes in the heart	14
Coenzyme Q10 ameliorates aging-induced memory deficits via modulation of apoptosis, oxidative stress, and mitophagy in aged rats	14
Changes in primitive reflexes in older adults and their relationship to mental health indices: An experimental investigation	14
Corrigendum to “Associations of daily steps and step intensity with peripheral arterial disease in Chinese community-dwelling older women” [Exp. Gerontol. 201 (2025) 112706]	14
Zhuyeqing liquor promotes longevity through enhancing stress resistance via regulation of SKN-1 and HSF-1 transcription factors in Caenorhabditis elegans	14
A bibliometric analysis of inflammation in sarcopenia from 2007 to 2022	14
Strength versus endurance trained master athletes: Contrasting neurophysiological adaptations	14
Inflammaging: The ground for sarcopenia?	14
Diclofenac, a NSAID, delays fracture healing in aged mice	13
Predictors of total mortality and their differential association on premature or late mortality in the SUN cohort	13
Gonadotropin-releasing hormone receptor pathway affects the function of human EBV-transformed B lymphocytes in an age-independent way	13
Heterogeneity in resistance training-induced muscle strength responses is associated with training frequency and insulin resistance in postmenopausal women	13
Older rats show slow modulation of hippocampal theta rhythm during voluntary running	13
The guppy (Poecilia reticulata) is a useful model for analyzing age-dependent changes in metabolism, motor function, and gene expression	13
MyomiR-OsteomiR crosstalk induced by different modes and intensities of exercise training and its role in controlling osteogenic differentiation in old male Wistar rats	13
Recognition of mild cognitive impairment in older adults using a polynomial regression model based on prefrontal cortex hemoglobin oxygenation	13
D-chiro-inositol increases antioxidant capacity and longevity of Caenorhabditis elegans via activating Nrf-2/SKN-1 and FOXO/DAF-16	13
Lower extremity performance predicts length of hospital stay in older candidates to elective cardiac surgery	13
Visual-related training to improve balance and walking ability in older adults: A systematic review	13
Unraveling the relationship between obstructive sleep apnea and osteoarthritis: A multivariate mendelian randomization highlighting the role of BMI as a confounding factor	13
Resistance exercise training at different loads in frail and healthy older adults: A randomised feasibility trial	13
Exergaming interventions for older adults: The effect of game characteristics on gameplay	13
Early life exercise impacts physiology and lifespan in a sex- and genotype-dependent manner in a Drosophila melanogaster exercise model	13
Aging-dependent mitochondrial bioenergetic impairment in the skeletal muscle of NNT-deficient mice	13
Modifiable predictive factors and all-cause mortality in the non-hospitalized elderly population: An umbrella review of meta-analyses	13
Respiratory training in older women: Unravelling central and peripheral hemodynamic slow oscillatory patterns	13
25-hydroxyvitamin D insufficiency and inflammation increase cardiovascular risk in older people	13
No impact of combining multi-ingredient supplementation with exercise on body composition and physical performance, in healthy middle-aged and older adults: A systematic review and meta-analysis	13
CHRNA1 induces sarcopenia through neuromuscular synaptic elimination	13
How important is current physical fitness for future quality of life? Results from an 8-year longitudinal study on older adults	13
Plasma volume variations in response to high intensity interval training in obese women: The influential role of menopausal status and age	13
Analysis of the effectiveness of a computerized cognitive stimulation program designed from Occupational Therapy according to the level of cognitive reserve in older adults in Primary Care: Stratified	13
Prolonged caloric restriction ameliorates age-related atrophy in slow and fast muscle fibers of rat soleus muscle	13
Exercise training partially rescues impaired mucosal associated invariant t-cell mobilization in breast cancer survivors compared to healthy older women	13
Oral frailty is associated with mortality independently of physical and psychological frailty among older adults	13
The role of transient receptor potential ankyrin 1 in age-related endothelial dysfunction	13
The mechanisms and functions of TNF-α in intervertebral disc degeneration	13
Contribution of impaired autophagy, mitochondrial dysfunction and abnormal lipolysis to epididymal aging in mice	12
ER stress in cardiac aging, a current view on the D-galactose model	12
Development and validation of an earphone-based system to measure short physical performance battery in older adults	12
Editorial Board	12
Acute catabolic bone metabolism response to exercise in young and older adults: A narrative review	12
Age-related morphological and functional changes in the small intestine of senescence-accelerated mouse	12
Data-driven physical actigraphy patterns relate to cognitive and vascular health in older adults	12
Modeling aging and its impact on cellular function and organismal behavior	12
Environmental enrichment modulates silent information regulator 1 (SIRT1) activity to attenuate central presbycusis in a rat model of normal aging	12
The effect of tibolone treatment on fasting blood sugar, insulin, insulin resistance and endothelial function in postmenopausal women: A meta-analysis of randomized controlled trials	12
Prospective associations of chronic and intrusive pain with sarcopenia and physical disability amongst older Australian men: The Concord Health and Ageing in Men Project	12
Motoric cognitive risk syndrome, physio-cognitive decline syndrome, cognitive frailty and reversibility with dual-task exercise	12
Anthropometry as a readily accessible health assessment of older adults	12
A prospective cohort study on the association between new falls and balancing ability among older adults over 80 years who are independent	12
Association of circulating C-reactive protein and high-sensitivity C-reactive protein with components of sarcopenia: A systematic review and meta-analysis of observational studies	12
Reduced cardiac response to the adrenergic system is a key limiting factor for physical capacity in old age	12
Pilot project. Resveratrol intake by physical active and sedentary older adult women and blood pressure	12
Prophylactic supplementation with selenium alters disposition of mercury in aged rats	12
Longitudinal evidence for immunosenescence and inflammaging in free-living great tits	12
Comparison of traditional vs. lighter load strength training on fat-free mass, strength, power and affective responses in middle and older-aged adults: A pilot randomized trial	12
Social frailty increases the risk of all-cause mortality: A longitudinal analysis of the English Longitudinal Study of Ageing	12
High-throughput sequencing analysis of the characteristics of the gut microbiota in aged patients with sarcopenia	12
Editorial Board	12
Comparison of the surgical efficacy of robot-assisted and freehand nail placement in the treatment of sarcopenia combined with femoral neck fractures younger than 65 years	12