Experimental Gerontology

Article	Citations
Assessing the causal relationship between frailty and sex hormone-binding globulin or insulin-like growth factor-1 levels: A sex-stratified bidirectional Mendelian Randomization study	159
Immunophenotypic characterization of B1a lymphocytes in Cuban older adults	139
Interaction of Klotho and sirtuins	99
Anti-fibrosis effect and its mechanism of atractylenolide III on post-traumatic extending knee joint contracture in rats	75
Association between weight-adjusted-waist index and serum anti-aging protein α-Klotho in U.S. adults: Evidence from NHANES 2007–2016	74
Is early life adversity a trigger towards inflammageing?	70
Association between the uremic toxins indoxyl-sulfate and p-cresyl-sulfate with sarcopenia and malnutrition in elderly patients with advanced chronic kidney disease	65
Diclofenac, a NSAID, delays fracture healing in aged mice	65
The effect of vitamin D on the lipid profile as a risk factor for coronary heart disease in postmenopausal women: a meta-analysis and systematic review of randomized controlled trials	63
No impact of combining multi-ingredient supplementation with exercise on body composition and physical performance, in healthy middle-aged and older adults: A systematic review and meta-analysis	62
Inflammatory biomarkers of frailty: A review	62
Association of circulating C-reactive protein and high-sensitivity C-reactive protein with components of sarcopenia: A systematic review and meta-analysis of observational studies	59
Biomarkers of the ageing immune system and their association with frailty – A systematic review	51
Dietary diversity and overweight are associated with high intrinsic capacity among Chinese urban older adults (2020−2021)	50
Effects of age, sex, frailty and falls on cognitive and motor performance during dual-task walking in older adults	49
Vascular endothelial dysfunction may be an early predictor of physical frailty and sarcopenia: A meta-analysis of available data from observational studies	48
Anthropometry as a readily accessible health assessment of older adults	48
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Whole organism aging: Parabiosis, inflammaging, epigenetics, and peripheral and central aging clocks. The ARS of aging	45
Human primary myoblasts derived from paraspinal muscle reflect donor age as an experimental model of sarcopenia	42
Altered resting-state neurovascular coupling in patients with pontine infarction	42
Neuromuscular adaptations to exercise and aging	42
Dose-response relationship between daily step count and prevalence of sarcopenia: A cross-sectional study	42
Low-intensity exercise improves cardiac tolerance to ischemia/reperfusion injury in aged female rats with metabolic syndrome	41
Nutritional quality of calorie restricted diets in the CALERIE™ 1 trial	39

The sweet fuel of inflammation: New perspectives on the complex web that interconnects diabetes	39
Age-related differences in stepping stability following a sudden gait perturbation are associated with lower limb eccentric control of the perturbed limb	38
Olfaction, ability to identify particular olfactory clusters and odors, and physical performance in community-dwelling older adults: The Yanai Study	38
Linoleic acid-derived oxylipins and isoprostanes plasma levels are influenced by 1,25-Dihydroxyvitamin D levels in middle-aged sedentary adults: The FIT-AGEING study	38
Identication and validation of cell senescence biomarkers in idiopathic pulmonary hypertension via integrated transcriptome analyses and machine learning	37
Lower extremity performance predicts length of hospital stay in older candidates to elective cardiac surgery	37
Neutrophil-lymphocyte ratio as a predictor of slow gait speed in older adults: The Rugao Longitudinal Aging Study	37
High-intensity interval training reduces the induction of neutrophil extracellular traps in older men using live-neutrophil imaging as biosensor	37
Senior Fitness Test in the assessment of the physical fitness of people with Parkinson's disease	37
Nutritional indicators' performance in malnutrition diagnosis of hospitalized elderly patients	37
Leg press and chest press strength normative values by half-decades in older persons	36
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Older rats show slow modulation of hippocampal theta rhythm during voluntary running	35
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Comparison of traditional vs. lighter load strength training on fat-free mass, strength, power and affective responses in middle and older-aged adults: A pilot randomized trial	34
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Impact of age and sex on heart rate variability and cardiometabolic function in healthy adults	32
Memory-related hippocampal brain-derived neurotrophic factor activation pathways from repetitive transcranial magnetic stimulation in the 3xTg-AD mouse line	32
Circulating cytokines and vascular dementia: A bi-directional Mendelian randomization study	32
A prospective cohort study on the association between new falls and balancing ability among older adults over 80 years who are independent	31
Sex differences in frailty among older adults	31
MyomiR-OsteomiR crosstalk induced by different modes and intensities of exercise training and its role in controlling osteogenic differentiation in old male Wistar rats	30
Fatigue and perceived energy in a sample of older adults over 10 years: A resting state functional connectivity study of neural correlates	30
Cytomegalovirus and herpes simplex type 1 infections and immunological profile of community-dwelling older adults	30
The pleiotropic beneficial intervention of olive oil intake on the Alzheimer's disease onset via fibrinolytic system	30
Fisetin-induced PTEN expression reverses cellular senescence by inhibiting the mTORC2-Akt Ser473 phosphorylation pathway in vascular smooth muscle cells	30
Enhancing fracture risk indication: The impact of bone load index and muscle fat infiltration on vertebral compression fracture	29
Cardiorespiratory fitness mediates the relationship between depressive symptomatology and cognition in older but not younger adults	29
Frequency and factors associated with sarcopenia prediction in adult and elderly patients hospitalized for COVID-19	29
Protective effects of emodin on subchondral bone and articular cartilage in osteoporotic osteoarthritis rats: A preclinical study	28
25-hydroxyvitamin D insufficiency and inflammation increase cardiovascular risk in older people	28
Longitudinal association between eating alone and deterioration in frailty status: The Korean Frailty and Aging Cohort Study	28
CircHIVEP2 alleviates Parkinson's nerve damage and inflammatory response by targeting miR-485-3p	27
Exercise drives metabolic integration between muscle, adipose and liver metabolism and protects against aging-related diseases	27
Recognition of mild cognitive impairment in older adults using a polynomial regression model based on prefrontal cortex hemoglobin oxygenation	27
Identification of toll-like receptor 2 as a key regulator of neuronal apoptosis in vascular dementia by bioinformatics analysis and experimental validation	27
Functionality loss due to COVID-19 hospitalisation in older adults recovers with inpatient rehabilitation: A systematic review and meta-analysis	27
Oral administration of liposome-encapsulated thymol could alleviate the inflammatory parameters in serum and hippocampus in a rat model of Alzheimer's disease	27
Exercise training for prevention and treatment of older adults with heart failure with preserved ejection fraction	26
Impact of repetitive home-based galvanic vestibular stimulation on cognitive skills in healthy older adults	26
Age-related structural changes show that loss of fibers is not a significant contributor to muscle atrophy in old mice	26
Analysis of the effectiveness of a computerized cognitive stimulation program designed from Occupational Therapy according to the level of cognitive reserve in older adults in Primary Care: Stratified	25
Functional restoration of lysosomes and mitochondria through modulation of AKT activity ameliorates senescence	25
Correlation between blood pressure and mortality in older critically ill patients: Insights from a large intensive care unit database	25
Role of fibroblast autophagy and proliferation in skin anti-aging	25
Are weight shifting and dynamic control strategies different in postmenopausal women with and without type-I osteoporosis?	25
Is playing ma-jong, chess and cards associated with a lower incidence of shoulder pain in Chinese elderly adults? The cross-sectional and longitudinal evidence from CHARLS	24
Long-term administration of soft drink causes memory impairment and oxidative damage in adult and middle-aged rats	24
High-throughput sequencing analysis of the characteristics of the gut microbiota in aged patients with sarcopenia	24

Association between single-point insulin sensitivity estimator and heart failure in older adults: A cross-sectional study	24
The role of mitochondrial quality control mechanisms in chondrocyte senescence	23
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Aging-dependent mitochondrial bioenergetic impairment in the skeletal muscle of NNT-deficient mice	23
The contribution of mitochondrial DNA alterations to aging, cancer, and neurodegeneration	23
Influence of age and sex on physical, cardiac electrical and functional alterations in progressive hyperoxia treatment: A time course study in a murine model	23
Preclinical frailty assessments: Phenotype and frailty index identify frailty in different mice and are variably affected by chronic medications	23
Balanced basal-levels of ROS (redox-biology), and very-low-levels of pro-inflammatory cytokines (cold-inflammaging), as signaling molecules can prevent or slow-down overt-inflammaging, and the aging-a	22
Effects of exercise on muscle mass, strength, and physical performance in older adults with sarcopenia: A systematic review and meta-analysis according to the EWGSOP criteria	22
The association between cardiovascular risk factors and major cardiovascular diseases decreases with increasing frailty levels in geriatric outpatients	22
Long-term intake of Lactobacillus paracasei KW3110 prevents age-related circadian locomotor activity and changes in gut metabolism in physiologically aged mice	22
Segmental extracellular-to-intracellular water resistance ratio and physical function in older adults	21
Exercise training partially rescues impaired mucosal associated invariant t-cell mobilization in breast cancer survivors compared to healthy older women	21
Are associations of leisure-time physical activity with mortality attenuated by high levels of chronic ambient fine particulate matter (PM2.5) in older adults? A prospective cohort study	21
Oral frailty is associated with mortality independently of physical and psychological frailty among older adults	21
High-velocity resistance training as a tool to improve functional performance and muscle power in older adults	21
Gonadotropin-releasing hormone receptor pathway affects the function of human EBV-transformed B lymphocytes in an age-independent way	20
Radiotherapy before or during androgen-deprivation therapy does not blunt the exercise-induced body composition protective effects in prostate cancer patients: A secondary analysis of two randomized c	20
Overexpression of solute carrier family 6 member 12 promotes cell injury in Parkinson's disease via MAPK signaling pathway	20
Vitamin D supplementation associated with 12-weeks multimodal training in older women with low bone mineral density: A randomized double-blind placebo-controlled trial	20
Lipoprotein subfractions in patients with sarcopenia and their relevance to skeletal muscle mass and function	20
Laboratory-assessed gait cycle entropy for classifying walking limitations among community-dwelling older adults	20
Motoric cognitive risk syndrome, physio-cognitive decline syndrome, cognitive frailty and reversibility with dual-task exercise	20
Evaluation of lifespan promoting effects of biofortified wheat in Drosophila melanogaster	20
Comparison of metabolic risk factors, physical performances, and prevalence of low back pain among categories determined by visceral adipose tissue and trunk skeletal muscle mass in middle-aged men	20
Systematic review on the effects of physical exercise on cellular immunosenescence-related markers – An update	19
Similarities and differences in kinetic characteristics of airways inflammation, formation of inducible bronchial-associated lymphoid tissue and remodeling between young and old murine asthma surrogat	19
Prolonged caloric restriction ameliorates age-related atrophy in slow and fast muscle fibers of rat soleus muscle	19
Segmental bioelectrical impedance spectroscopy: A novel field assessment of muscle size and quality in normal weight and obese older men	19
Subjective hearing handicap is associated with processing speed and visuospatial performance in older adults without severe hearing handicap	19
Transient speeding of V̇O2 kinetics following acute sessions of sprint interval training: Similar exercise dose but different outcomes in older and young adults	19
Unresolved inflammation during hospitalization is associated with post-discharge institutionalization and mortality in geriatric rehabilitation inpatients: The RESORT cohort	19
Mediating effect of muscle power on the relationship of physical activity with physical fitness and physical function in older women	19
Evidence of resistance training-induced neural adaptation in older adults	19
A pilot investigation of reliability and validity of balance and gait assessments using telehealth with healthy older adults	19
Oligosaccharides from Sargassum thunbergii inhibit osteoclast differentiation via regulation of IRF-8 signaling	18
Gait speed, handgrip strength, and cognitive impairment among older women – A multistate analysis	18
Frailty increases depression risk independently of cognitive decline: Insights from Mendelian randomization and cross-sectional analysis	18
Impaired cardiac mechanical synchrony revealed with increased myocardial work in women with advanced age	18
The guppy (Poecilia reticulata) is a useful model for analyzing age-dependent changes in metabolism, motor function, and gene expression	18
Cross-sectional study and bioinformatics analysis to reveal the correlations of osteoporosis in patients with Parkinson's disease	18
Effects of an inulin fiber diet on the gut microbiome, colon, and inflammatory biomarkers in aged mice	18
CHRNA1 induces sarcopenia through neuromuscular synaptic elimination	18
Interindividual variability of adaptations following either traditional strength or power training combined to endurance training in older men: A secondary analysis of a randomized clinical trial	18
Effects of multi-domain intervention on intrinsic capacity in older adults: A systematic review of randomized controlled trials (RCTs)	18
The D allele of angiotensin-converting enzyme gene is associated with a worse autonomic heart control in community-based older adults	17
Statin use moderates the beneficial effects of aerobic exercise on older adults' performances on the Stroop test: A subanalysis	17
Association between Cav3 channel upregulation in spiral ganglion neurons and age-dependent hearing loss	17
Exergaming interventions for older adults: The effect of game characteristics on gameplay	17
Unraveling the relationship between obstructive sleep apnea and osteoarthritis: A multivariate mendelian randomization highlighting the role of BMI as a confounding factor	17
CRISPR-Cas9 mediated d3GHR knockout in HEK293 cells: Revealing the longevity associated isoform stress resilience	17
In aged rats, differences in spatial learning and memory influence the response to late-life Environmental Enrichment	17
Resistance exercise training at different loads in frail and healthy older adults: A randomised feasibility trial	17
Determinants of cardiac structure in frail and sarcopenic elderly adults	17
Exploring the effects of combining health qigong and dance on working memory in middle-aged and elderly women: A preliminary investigation	17
Sarcopenia in cirrhosis: From pathophysiology to interventional therapy	17
Immediate effects of structured and natural deep breathing on heart rate variability and blood pressure in community-dwelling older adults	17
Effects of aging on the cholinergic innervation of the rat ventral tegmental area: A stereological study	17
Plasma 25-hydroxyvitamin D levels, quality of life, inflammation and depression in older adults: Are they related?	17
How important is current physical fitness for future quality of life? Results from an 8-year longitudinal study on older adults	17
Pegylated chitosan nanoparticles of fluoxetine enhance cognitive performance and hippocampal brain derived neurotrophic factor levels in a rat model of local demyelination	17
Calorie restriction and life-extending mutation downregulate miR-34a to facilitate lipid metabolism in the liver	17
Plasma volume variations in response to high intensity interval training in obese women: The influential role of menopausal status and age	17
Association of SARC-F and dissociation of SARC-F + calf circumference with comorbidities in older hospitalized cancer patients	16
Effect of intermittent hypoxic conditioning on inflammatory biomarkers in older adults	16
Sleep problems and mild cognitive impairment among adults aged ≥50 years from low- and middle-income countries	16
Predictors of total mortality and their differential association on premature or late mortality in the SUN cohort	16
Directed connectivity in Parkinson's disease patients during over-ground and treadmill walking	16
Heterogeneity in resistance training-induced muscle strength responses is associated with training frequency and insulin resistance in postmenopausal women	16
The influence of age on the recovery from worksite resistance exercise in career firefighters	16
Neuronal and glial region dependent changes in female mice from a model of premature aging	16
Receiving financial support and its association with late-age depression: The mediating role of social engagement	16
High-intensity interval aerobic and resistance training to counteract low relative lean soft tissue mass in middle age: A randomized controlled trial	16
Rhythmic musical activities may strengthen connectivity between brain networks associated with aging-related deficits in timing and executive functions	16
Food hardness influences the progression of age-related hearing loss in mice	16
Age-related morphological and functional changes in the small intestine of senescence-accelerated mouse	16
Chronic rapamycin pretreatment modulates arginase/inducible nitric oxide synthase balance attenuating aging-dependent susceptibility to Trypanosoma cruzi infection and acute myocarditis	16
Charlson comorbidity index is not associated with neutrophil-lymphocytes ratio in unselected hospitalized cancer patients: A cross-sectional study	16
Acute catabolic bone metabolism response to exercise in young and older adults: A narrative review	16
Rapamycin impairs bone accrual in young adult mice independent of Nrf2	16

Statin is associated with higher cortical thickness in early Alzheimer's disease	15
Activation of α7nAChR by PNU282987 improves cognitive impairment through inhibiting oxidative stress and neuroinflammation in D-galactose induced aging via regulating α7nAChR/Nrf2/HO-1 signaling pathw	15
Modifiable predictive factors and all-cause mortality in the non-hospitalized elderly population: An umbrella review of meta-analyses	15
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Corrigendum to “Daily behavioral and sleep patterns are associated with aging-induced male-specific disorders in individuals with reduced renal function” [Exp. Gerontol. 16 (2022) 1–7 (111717)]	15
Social frailty increases the risk of all-cause mortality: A longitudinal analysis of the English Longitudinal Study of Ageing	15
Muscle weakness is a prognostic indicator of disability and chronic disease multimorbidity	15
Corrigendum to “Segmental extracellular-to-intracellular water resistance ratio and physical function in older adults” [Exp. Gerontol. 181 (2023) 112278]	15
Effect of exercise on inflammatory markers in postmenopausal women with overweight and obesity: A systematic review and meta-analysis	15
The biological roots of the sex-frailty paradox	14
MicroRNA-139-5p inhibits vascular endothelial cell viability and serves as a diagnostic biomarker in acute myocardial infarction patients	14
Identification of therapeutic target genes for age-related hearing loss through systematic genome-wide mendelian randomization of druggable genes	14
Inhibition of 15-PGDH by SW033291 ameliorates age-related heart failure in mice	14
Early life exercise impacts physiology and lifespan in a sex- and genotype-dependent manner in a Drosophila melanogaster exercise model	14
Unveiling FOXO3's metabolic contribution to menopause and Alzheimer's disease	14
Respiratory training in older women: Unravelling central and peripheral hemodynamic slow oscillatory patterns	14
Association between urinary trace elements levels and depressive symptoms among the older population	14
The role of transient receptor potential ankyrin 1 in age-related endothelial dysfunction	14
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Inhibitor PF-04691502 works as a senolytic to regulate cellular senescence	14
Relationship between handgrip strength and self-reported functional difficulties among older Indian adults: The role of self-rated health	13
Ergothioneine and its prospects as an anti-ageing compound	13
Visual-related training to improve balance and walking ability in older adults: A systematic review	13
Senolytic agents lessen the severity of abdominal aortic aneurysm in aged mice	13
Mediterranean diet in the management and prevention of obesity	13
The mechanisms and functions of TNF-α in intervertebral disc degeneration	13
Serum irisin level is independent of sarcopenia and related muscle parameters in older adults	13
Non pharmacoligical approaches for neurodegenerative diseases: A narrative review	13
A meta-analysis of RNA-Seq studies to identify novel genes that regulate aging	13
Saponins of Panax japonicus ameliorates cardiac aging phenotype in aging rats by enhancing basal autophagy through AMPK/mTOR/ULK1 pathway	13
Sauna use as a lifestyle practice to extend healthspan	13
Low muscle mass in older adults and mortality: A systematic review and meta-analysis	13
Combining the AD8 and MMSE for community-based dementia screening	13
Wasting syndrome and associated factors in hospitalized older people	12
Oral frailty as a risk factor for mild cognitive impairment in community-dwelling older adults: Kashiwa study	12
Panax ginseng and aging related disorders: A systematic review	12
Standing up to threats: Translating the two-system model of fear to balance control in older adults	12
The mitochondrial function of peripheral blood mononuclear cells in frail older patients	12
D-chiro-inositol increases antioxidant capacity and longevity of Caenorhabditis elegans via activating Nrf-2/SKN-1 and FOXO/DAF-16	12
Abnormal postcentral gyrus voxel-mirrored homotopic connectivity as a biomarker of mild cognitive impairment: A resting-state fMRI and support vector machine analysis	12
Inhibition of mTOR by rapamycin does not improve hypoxic pulmonary hypertension-induced right heart failure in old mice	12
Gait speed reference values in community-dwelling older adults – Cross-sectional analysis from the Rotterdam Study	12
Simpler modified fried frailty scale as a practical tool to evaluate physical frailty: Methodological report for its cross-cultural adaptation and validation	12
Aerobic exercise attenuates abnormal myelination and oligodendrocyte differentiation in 3xTg-AD mice	12
Age and sex mediated effects of estrogen and Β3-adrenergic receptor on cardiovascular pathophysiology	12
Development and validation of a risk prediction model for frailty in older nappers	12
Obesity classified by anthropometric parameters was associated with mitochondrial bioenergetics impairment of peripheral blood mononuclear cells in the elderly population	12
The effect of tamoxifen on the lipid profile in women: A systematic review and meta-analysis of randomized controlled trials	12
Association between sarcopenic obesity and osteoarthritis: The potential mediating role of insulin resistance	12
The effect of tamoxifen as an adjuvant therapy for breast cancer on apolipoproteins and lipoprotein(a) concentrations in women: A meta-analysis of randomized controlled trials	12
The interplay between osteoarthritis and osteoporosis: Mechanisms, implications, and treatment considerations – A narrative review	12
Comparative study of brain damage and oxidative stress using two animal models of the shaken baby syndrome	12
Modeling aging and its impact on cellular function and organismal behavior	12
The effect of high intensity interval training with genistein supplementation on mitochondrial function in the heart tissue of elderly rats	12
High-fat diet and dyslipidemia synergistically contribute to T cell senescence in gut associated lymphoid tissue	12
Effects of fasting on skeletal muscles and body fat of adult and old C57BL/6J mice	11
Preventing age-related motor unit loss; is exercise the answer?	11
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Drosophila melanogaster flies better know than us the nutrients they need: Let them choose	11
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Hearing aids utilization, effect factors, and its benefit in the association between hearing and cognition decline: A longitudinal follow-up in Shanghai, China	11
Considerations for carotid artery disease management in a frail population	11
The effect of tibolone treatment on fasting blood sugar, insulin, insulin resistance and endothelial function in postmenopausal women: A meta-analysis of randomized controlled trials	11
Systemic oxidative stress in old rats is associated with both osteoporosis and cognitive impairment	11
β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN	11
Thyroid nodules and its association with vitamin D in centenarians	11
Cardioprotective effects of exercise preconditioning on ischemia-reperfusion injury and ventricular ectopy in young and senescent rats	11
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Neurotropic peptide HLDF-6-amide reduces age-related decline in sexual activity in old male rats	11
Parental age at death is associated with age at first birth in offspring	11
Changes in the tight junctions of the testis during aging: Role of the p38 MAPK/MMP9 pathway and autophagy in Sertoli cells	11
Age-related decrease in serum dihydrotestosterone concentration is accompanied by impaired vascular status	11
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Quantitative analysis of balance function characteristics in older patients with mild to moderate cognitive impairment	11
Association between vitamin D receptor polymorphism and breast cancer in women: An umbrella review of meta-analyses of observational investigations	10
How are combinations of physical activity, sedentary behaviour and sleep related to cognitive function in older adults? A systematic review	10
Plasma phosphatidylcholines and vitamin B12/folate levels are possible prognostic biomarkers for progression of Alzheimer's disease	10
Impact of COVID-19 lockdown on health parameters and muscle strength of older women: A longitudinal study	10
A metagenomics study reveals the gut microbiome as a sex-specific modulator of healthy aging in Hainan centenarians	10
Commentary: The sit-to-stand muscle power test: An easy, inexpensive and portable procedure to assess muscle power in older people	10
Central obesity and elevated blood pressure in middle life are associated with physical and cognitive impairment in later life: A retrospective design with repeated measures	10
The role of cytokine receptor-like factor 1 (CRLF1) in facet joint osteoarthritis pathogenesis	10
The promise of amplification assays for accurate early detection of α-synucleinopathies: A review	10
The relationship between nutrition and depression in the life process: A mini-review	10
Risk of non-vertebral fractures in men with type 2 diabetes: A systematic review and meta-analysis of cohort studies	10
Changes to margins of stability from walking to obstacle crossing in older adults while walking fast and with a dual-task	10
Cellular senescence and the senescence-associated secretory phenotype: Potential therapeutic targets for renal fibrosis	10
ER stress in cardiac aging, a current view on the D-galactose model	10
Inoculation of lymphocytes from young mice prevents progression of age-related hearing loss in a senescence-associated mouse model	10
Sarcopenia in community-dwelling older adults is associated with the diversity and composition of the gut microbiota	10