OOIR: Observatory of International Research

Papers

(The median citation count of Electronic Journal of Biotechnology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Circulating exosomal miRNA signatures as potential biomarkers and therapeutic targets in biliary colic	61
Identification and validation of adenylate uridylate (AU)-rich element (ARE)-related biomarkers in the process of treating lung cancer mice with Wenyang Hualiu Tang through bulk RNA sequencing and ani	39
Antioxidant, and enzyme inhibition effects of chia (Salvia hispanica) seed oil: A comprehensive phytochemical screening using LC-HR/MS	35
Therapeutic effect of biosynthesized silver nanoparticles on hypothyroidism induced in albino rats	34
Bioremediation of waste by yeast strains	34
Low-alcohol light beer enriched with olive leaves extract: Cold mashing technique associated with interrupted fermentation in the brewing process	29
Screening and analysis of candidate genes conferring alkalinity tolerance in rice (Oryza sativa L.) at the bud burst stage based on QTL-seq and RNA-seq	28
Relationship between type II polyproline helix secondary structure and thermal hysteresis activity of short homopeptides	24
Development of a chemically defined medium for Yarrowia yeasts using a strategy of biological mimicry	24
Molecular targets and mechanisms of resveratrol in alleviating arrhythmia based on network pharmacology and bioinformatics	24
Integrated analysis reveals potential significance of FKBP5 in the prognosis and immunity of osteoarthritis and pan-cancer	22
QTL analysis of low-temperature tolerance in maize germination by SLAF-seq and BSA technique	21
The cadCA and cadB/DX operons are possibly induced in cadmium resistance mechanism by Frankia alni ACN14a	17
A sustainable exploitation of high-protein feather waste for production of cold-adapted keratinase by Penicillium lanosocoeruleum KSA-55	14
Onion peel-mediated biosynthesis of TiO2-ZnO bimetallic nanoparticles: Antimicrobial, antibiofilm, and anticancer activities	13
Novel bacterial plasmid produces small interfering RNAs (siRNAs) that induce effective gene silencing in the Asian citrus psyllid Diaphorina citri	13
Molecular characterization of cellulase genes in Pseudomonas stutzeri	13
Biochemical and in silico evaluation of a recombinant, glucose tolerant, and highly thermostable β-glucosidase from Thermococcus radiotolerans DSM-15228	12
FTIR and multivariate analysis of total phenolic content, antioxidant and anti-amylase activities of extracts and milk of Glycine max L. and Phaseolus vulgaris L.	12
Circular RNA FMN2 motivates colorectal cancer development by mediating tumor-associated macrophage polarization by controlling the microRNA-150-5p/PIK3R3 axis	12
Sheep IGFBP2 and IGFBP4 promoter methylation regulates gene expression and hair follicle development	12
Efficacy of powder of ginsengporia and atractylodis macrocephalae combined with aerobic exercise in the treatment of obese T2DM: A randomized controlled clinical trial	11
Obituary for James D. Watson (1928–2025)	11
Selection and validation of reference genes for quantitative real-time PCR in different tissues of Clematis lanuginosa	11
Overexpression of VvLRK10L affected the development of Arabidopsis thaliana	11

Induction temperature impacts the structure of recombinant HuGM-CSF inclusion bodies in thermoinducible E. coli	11
Construction, heterological expression and a simple purification of the BP region of the pneumococcal surface protein A fused in different orientations to the chemotaxis adaptor protein CheW from Ther	11
miR-379-3p inhibits fat grafting survival and angiogenesis by targeting SOCS1-mediated adipose inflammation	10
Reverse osmosis membranes applied in seawater desalination plants as a source of bacteria with antifouling activity: Isolation, biochemical and molecular characterization	9
Upregulation of ITGAV and the underlying mechanisms in nasopharyngeal carcinoma	9
Supplementation of beer with Pinus sylvestris L. shoots extracts and its effect on fermentation, phenolic content, antioxidant activity and sensory profiles	8
The significance of chemical transfection/transduction enhancers in promoting the viral vectors-assisted gene delivery approaches: A focus on potentials for inherited retinal diseases	8
A novel nanoemulsion based on clove and thyme essential oils: Characterization, antibacterial, antibiofilm and anticancer activities	8
ALYREF promotes malignant behaviors and inhibits ferroptosis in colon cancer cells by stabilizing PCSK9 mRNA	8
Estrogen attenuates colonic mucinous adenocarcinoma growth in a rat model by inhibiting proliferation and promoting apoptosis	7
The evolution of isothermal amplification technology: A bibliometric study (2013–2022)	7
Enhancing Lactobacillus plantarum viability using novel chitosan-alginate-pectin microcapsules: Effects on gastrointestinal survival, weight management, and metabolic health	7
Optimizing conditions for augmented production of amylase by Talaromyces islandicus AUMC 11391	7
Isolation, purification and physicochemical characterization of Cichorium intybus L. root polysaccharide and its protective effect against CCl4-induced liver injury	7
Ginsenoside protects intestinal barrier function and improves epithelium injury in sepsis by regulating the miR-30e-5p/FBXO11 axis	7
Successful CRISPR/Cas9-mediated HDR at individual DNA breakpoints using TFO-based targeted template design	7
Isolation and characterization of fungi producing L-asparaginase with reduced L-glutaminase activity from soil samples	7
Oxidative stress gene signature associated with vitiligo: A multi-algorithm machine learning and Mendelian randomization validation	7
High-level expression of an acetaldehyde dehydrogenase from Lactiplantibacillus plantarum and preliminary evaluation of its potential as a functional food additive	7
SNORD3A acts as a potential prognostic and therapeutic biomarker in gastric cancer	6
Whole-genome analysis and biosynthetic gene cluster profiling of Stenotrophomonas sp. ASucR1 isolated from Sof Umer Cave, Ethiopia	6
Biogenesis of nanoparticles with inhibitory effects on aflatoxin B1 production by Aspergillus flavus	6
Antimicrobial characteristics of endophytic Aspergillus terreus and acute oral toxicity analysis	6
Prognostic implication of a ferroptosis-related gene signature associates with immunity in Ewing’s sarcoma	6
A novel nanocomposite based on mycosynthesized bimetallic zinc-copperoxide nanoparticles, nanocellulose and chitosan: Characterization, antimicrobial and photocatalytic activities	5
Analysis and identification of the main antimicrobial metabolites of Lactobacillus plantarum LPZN19	5
Selection and validation of stable reference genes in guava (Psidium guajava L.) for reliable and consistent gene expression analysis	5
Network pharmacology and experimental verification reveal the mechanism of Qingfei Tongluo mixture in treating pulmonary fibrosis	5
Improvement of techno-functional properties of acidic subunit from amaranth 11S globulin modified by bioactive peptide insertions	5
Improved resistance to basal rot disease and promotion of onion plant growth by Aspergillus terreus-mediated silver nanoparticles	5
circUBAP2 ameliorates hypoxia-induced acute myocardial injury by competing with miR-148b-3p and mediating CDKN1B expression	5
Surfactant protein D regulates Notch activity for secretory cell repair and regeneration to prevent post-acute pancreatitis diabetes	5
Comprehensive expression analysis reveals upregulated LUZP2 in prostate cancer tissues	4
Exploring the molecular mechanism of resveratrol for the treatment of lung adenocarcinoma based on molecular docking	4
Establishment of deer heart identification method and development of the detection kit based on mitochondrial cytochrome B gene	4
Biological activity of peptides isolated from feather keratin waste through microbial and enzymatic hydrolysis	4
Synthesis of hot spring origin bacterial cell wall polysaccharide-based copper nanoparticles with antibacterial property	4
Novel antioxidant additive ENTAN molecule for animal production: Evaluation at the cellular level	4
Identification of MORC2 via bioinformatics and machine learning reveals its transcriptional activation by PAX2 in NSCLC malignancy	4
Formation of osteoconductive biograft with bioorganic scaffold, human mesenchymal stromal cells, and platelet-rich plasma with its evaluation in vitro	3
TGFβ3 regulates adipogenesis of bovine subcutaneous preadipocytes via typical Smad and atypical MAPK signaling pathways	3
Qualitative phytochemical analysis, thin-layer chromatographic profiling, and antimicrobial potential of banana cultivars	3
ANKRD1 knockdown attenuates doxorubicin-induced dilated cardiomyopathy by regulating mitochondrial dysfunction and oxidative stress through activation of the AMPK/AKT/mTOR pathway	3
Evaluation of high-value bioproducts production by marine endophytic fungus Arthrinium sp. FAKSA 10 under solid state fermentation using agro-industrial wastes	3
Can broad bean (Vicia faba) and white lupin (Lupinus albus) flours serve as carbon sources to support probiotic growth?	3
Metabolites of native actinomycetes from Sof Umer cave reveal potent antimicrobial activity against selected pathogens in mice infection models	3
Salinity generates varying chemical and biochemical responses in Physalis ixocarpa (Solanaceae) during different times of exposure	3
Chufeng Yisun Decoction treats dry eye syndrome by inhibiting the PI3K/Akt pathway	3
Octoploid blueberry development for drought tolerance: A combined approach of in vitro polyploidization and somatic organogenesis	3
Whole-transcriptome analysis reveals the characteristics of intramuscular fat circRNA expression and its associated network in grazing yaks of different months of age under cold stress	3

Identification and verification of diagnostic biomarkers related to matrisome in patients with knee osteoarthritis based on machine learning algorithms	3
Efficient production of 6-hydroxynicotinic acid by newly isolated Pseudomonas poae	3
Genome analysis and CAZy repertoire of a novel fungus Aspergillus sydowii C6d with lignocellulolytic ability isolated from camel rumen	3
METTL16 promotes osteosarcoma progression by inducing m6A methylation of the UBE3A and Notch signaling pathway	2
Tianma granules: Bridging traditional medicine and modern science to combat colorectal cancer via ferroptosis	2
Novel Erodium glaucophyllum (L.) Aiton growing in arid environment: Phytochemical characterization, antimicrobial, antioxidant, and anticancer potential	2
Peptides, solid-phase synthesis and characterization: Tailor-made methodologies	2
Antibiotic evaluation of the nanocomposites IONs-MWCNTs-Pc and IONs-GO-Pc encapsulated in the biocompatible hydrogel poly(VCL-co-PEGDA) based on photodynamic effect	2
Cotton promoters for controlled gene expression	2
Green synthesis of silver nanoparticles using Viola odorata and Onosma hispidum: Evaluation of their antimicrobial, antioxidant, and hemolytic properties against multidrug-resistant microbes	2
Unveiling microbial secondary metabolite biosynthetic gene clusters from alkaline soda Lake Chitu, in the Ethiopian Rift Valley	2
Statistical optimization of media components for antibiotic production in Streptomyces sp. CMSTAAHAL-3	2
LOXL2 promotes tumor proliferation and metastasis by FAK/Src signaling in esophageal squamous cell carcinoma	2
Optimization of fructose-rich syrups production from Opuntia ficus-indica inulin using immobilized inulinase on Luffa cylindrical	2
Electrotransformation optimization of plasmid pGAPZαA – CecMd3cs into Pichia pastoris GS115 with response surface methodology	2
Integrated single-cell RNA sequencing and multi-database analysis reveal THBS2 promotes high glucose-induced mesangial cell oxidative stress and fibrosis in diabetic nephropathy	2
Xylitol production by a Wickerhamomyces anomalus strain adapted for enhanced tolerance to sugarcane bagasse hemicellulosic hydrolysate with high content of fermentation inhibitors	2
Dr. Rodolfo Quintero Ramírez (21/07/1947–08/12/2024)	2