Pharmaceutical Research

Article	Citations
Discovery and Control of Succinimide Formation and Accumulation at Aspartic Acid Residues in The Complementarity-Determining Region of a Therapeutic Monoclonal Antibody	153
Cationic Ester Prodrugs of Curcumin with N,N-dimethyl Amino Acid Promoieties Improved Poor Water Solubility and Intestinal Absorption	147
Engineering a Remedy to Modulate and Optimize Biopharmaceutical Properties of Rebamipide by Synthesizing New Cocrystal: In Silico and Experimental Studies	112
Combating Alcohol Adduct Impurity in Immunosuppressant Drug Product Manufacturing: A Scientific Investigation for Enhanced Process Control	99
Unambiguous Identification of Glucose-Induced Glycation in mAbs and other Proteins by NMR Spectroscopy	79
Thermo-Responsive Polymer-siRNA Conjugates Enabling Artificial Control of Gene Silencing around Body Temperature	77
Analytical Workflows to Unlock Predictive Power in Biotherapeutic Developability	73
Limited Impact of Murine Placental MDR1 on Fetal Exposure of Certain Drugs Explained by Bypass Transfer Between Adjacent Syncytiotrophoblast Layers	69
Modeling Gasotransmitter Availability to Brain Capillary Endothelial Cells with Ultrasound-sensitive Microbubbles	62
Ritonavir-Boosted Exposure of Kinase Inhibitors: an Open Label, Cross-over Pharmacokinetic Proof-of-Concept Trial with Erlotinib	60
Perspectives on the Wetting of Solids in Pharmaceutical Systems	54
Computational and Experimental Screening Approaches to Aripiprazole Salt Crystallization	49
Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice	48
Development of Amorphous Solid Dispersion Sustained-Release Formulations with Polymer Composite Matrix-Regulated Stable Release Plateaus	44
In Vitro and In Silico Investigations on Drug Delivery in the Mouth-Throat Models with Handihaler®	41
Drug Release from Surfactant-Containing Amorphous Solid Dispersions: Mechanism and Role of Surfactant in Release Enhancement	39
Effect of Fatty Acid Composition in Polysorbate 80 on the Stability of Therapeutic Protein Formulations	39
Relative Performance of Volume of Distribution Prediction Methods for Lipophilic Drugs with Uncertainty in LogP Value	39
Safety and Pharmacokinetics of Intranasally Administered Heparin	38
Novel Deep Eutectic Solvent–Hydrogel Systems for Synergistic Transdermal Delivery of Chinese Herb Medicine and Local Treatments for Rheumatoid Arthritis	38
Pharmacokinetic Assessment of Drug Efflux from Erythrocytes Loaded with Corticosteroid Esters	37
Brain Targeted Curcumin Loaded Turmeric Oil Microemulsion Protects Against Trimethyltin Induced Neurodegeneration in Adult Zebrafish: A Pharmacokinetic and Pharmacodynamic Insight	37
Correction: A Preformulation Experiment: The Influence of Poloxamer 188 and Poloxamer 407 on the Binding Coefficients (Single Molecule) and the Partitioning Coefficients (Micelle) of Ketoprofen (Probe	36
Professor Margareta Hammarlund-Udenaes – a Modern and Visionary Mentor	36
PEGylation of Propofol Reduces Its Adsorption to Extracorporeal Membrane Oxygenator (ECMO) Components	35

Controlling Gastric Delivery of a GIP/GLP1 Peptide in Monkeys by Mucoadhesive SNAC Tablets	33
Droplet-Based Microfluidic Tool to Quantify Viscosity of Concentrating Protein Solutions	33
Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells	33
Revolutionizing Heart Failure Therapy: Harnessing IVT mRNA and Fusion Protein Technology to Prolong rhBNP Half-Life	33
Advancements in Particle Engineering for Inhalation Delivery of Small Molecules and Biotherapeutics	32
Therapeutic Potential of Semaglutide, a Newer GLP-1 Receptor Agonist, in Abating Obesity, Non-Alcoholic Steatohepatitis and Neurodegenerative diseases: A Narrative Review	32
Utilizing Octanoic Acid to Quantitatively Assess the Oxidation Status of PS80	32
Role of Disease Progression Models in Drug Development	32
Delivery of Corn-Derived Nanoparticles with Anticancer Activity to Tumor Tissues by Modification with Polyethylene Glycol for Cancer Therapy	31
Predicting Leachables Solubilization in Polysorbate 80 Solutions by a Linear Solvation Energy Relationship (LSER)	30
Micafungin Population PK Analysis in Healthy and Septic Pigs: Can the Septic Porcine Model Predict the Micafungin PK in Septic Patients?	30
Cortisol as Biomarker for CYP17-Inhibition is Associated with Therapy Outcome of Abiraterone Acetate	30
Coupling Drug Dissolution with BCS	29
Editorial Expression of Concern: Regulation of miR-19 to Breast Cancer Chemoresistance Through Targeting PTEN	29
Photo-Oxidation Mechanisms in Liquid Pharmaceutical Formulations: The Overlooked Role of Singlet Oxygen Presented as a Case Study	29
Enhanced Penetration and Retention of an Antibody in the Articular Cartilage Through Aggrecan Binding and Molecular Downsizing	29
RETRACTED ARTICLE: Characterization of Preclinical Pharmacokinetic Properties and Prediction of Human PK Using a Physiologically Based Pharmacokinetic Model for a Novel Anti-Arrhythmic Agent Sulcardin	29
Learning Chemotherapy Drug Action via Universal Physics-Informed Neural Networks	29
Multiphysics Modelling and Simulation of Thrombolysis via Activated Platelet-Targeted Nanomedicine	28
Design of an Ante-enhancer with an Azone-Mimic Structure using Ionic Liquid	28
Design Considerations for Intratracheal Delivery Devices to Achieve Proof-of-Concept Dry Powder Biopharmaceutical Delivery in Mice	28
Phase Transitions Involving Channel Hydrates of a New Pharmaceutical Compound	28
Modification of Peptide and Permeation Enhancer In Vitro Release Rates by Dispersion with a Gel-Forming Polymer	28
Novel Pharmaceutical Cocrystals of Tegafur: Synthesis, Performance, and Theoretical Studies	27
Investigation of an Uncommon Artifact during Reducing Capillary Electrophoresis-Sodium Dodecyl Sulfate Analysis of a Monoclonal Antibody with Dynamic Light Scattering and Reversed Phase High-Performan	27
PAMAM versus PEI complexation for siRNA delivery: interaction with model lipid membranes and cellular uptake	27
Peptide Acylation in Aliphatic Polyesters: a Review of Mechanisms and Inhibition Strategies	26
Model-Guided Development of a Semi-Continuous Drying Process	26
A Novel Combination Therapy of Erythropoietin and Thrombopoietin to Treat Erythropoietin-Resistance anemia	26
Generic Enrichment Method for Liquid Chromatography-Multiple Reaction Monitoring-Mass Spectrometry Assay for Quantitative Measurement of Biological Therapeutics in Serum	25
Improved Pharmaceutical Properties of Honokiol via Salification with Meglumine: an Exception to Oft-quoted ∆pKa Rule	25
Microdialysis of Drug and Drug Metabolite: a Comprehensive In Vitro Analysis for Voriconazole and Voriconazole N-oxide	25
Physiologically-Based Pharmacokinetic Modeling of PAXLOVID™ with First-Order Absorption Kinetics	25
Topical Semisolid Drug Product Critical Quality Attributes with Relevance to Cutaneous Bioavailability and Pharmacokinetics: Part I—Bioequivalence of Acyclovir Topical Creams	25
Strategy for Cytoplasmic Delivery Using Inorganic Particles	24
Oral Delivery of Nucleic Acid Therapies for Local and Systemic Action	24
Optimization of Vancomycin Initial Dose in Term and Preterm Neonates by Machine Learning	24
Elucidating the Impact of Material Properties on Tablet Manufacturability for Binary Paracetamol Blends	22
N-terminus of Etanercept is Proteolytically Processed by Dipeptidyl Peptidase-4	22
Retraction Note: Characterization of Preclinical Pharmacokinetic Properties and Prediction of Human PK Using a Physiologically Based Pharmacokinetic Model for a Novel Anti-Arrhythmic Agent Sulcardine	22
Predictive Value of Vancomycin AUC24/MIC Ratio for 30-day Mortality in Patients with Severe or Complicated Methicillin-Resistant Staphylococcus aureus Infections: A Multicenter Retrospective Study	22
Temperature and Heat Transfer Control During Freeze Drying. Effect of Vial Holders and Influence of Pressure	22
Correction to: Re-examining digoxin bioavailability after half a century: Time for changes in the bioavailability concepts	22
Application of Twin-Screw Melt Granulation to Overcome the Poor Tabletability of a High Dose Drug	22
Decrease in In Vivo Efflux Transport via P-glycoprotein at the Rat Inner Blood-Retinal Barrier by Peripheral Administration of Lipopolysaccharide	21
Evaluation of Blood-CSF Barrier Transport by Quantitative Real Time Fluorescence Microscopy	21
Hydration Mechanism and Its Effect on the Solubility of Aripiprazole	21
Evaluation of the Robustness of Therapeutic Drug Monitoring Coupled with Bayesian Forecasting of Busulfan with Regard to Inaccurate Documentation	21
Formulation and Validation of an Extended Sigmoid Emax Model in Pharmacodynamics	21
The Osmolality and Hemolysis of High-Concentration Monoclonal Antibody Formulations	21

Sensitivity and Uncertainty Analysis of Micro-Flow Imaging for Sub-Visible Particle Measurements Using Artificial Neural Network	21
Nanobody-Oligonucleotide Conjugates (NucleoBodies): The Next Frontier in Oligonucleotide Therapy	20
Dissolution Profiles of Poorly Soluble Drug Salts in Bicarbonate Buffer	20
Time-Lapse Macro Imaging with Dissolution Tests for Exploring the Interrelationship Between Disintegration and Dissolution Behaviors of Solid Dosages	19
Fluorinated PAMAM-Arginine Carrier Prodrugs for pH-Sensitive Sustained Ibuprofen Delivery	19
Accelerating Process Development and Product Formulation	19
Correction to: Liposomal Formulation for Oral Delivery of Cyclosporine A: Usefulness as a Semisolid-Dispersion System	19
Progress in the Application of Microneedles in Eye Disorders and the Proposal of the Upgraded Microneedle with Spinule	19
Understanding the Phagocytosis of Particles: the Key for Rational Design of Vaccines and Therapeutics	19
A Model-Based Evaluation of Noninvasive Biomarkers to Reflect Histological Nonalcoholic Fatty Liver Disease Scores	19
Application of PAT Probes in Aluminum Phosphate Adjuvant Manufacturing	19
Novel Quantification of Extracellular Vesicles with Unaltered Surface Membranes Using an Internalized Oligonucleotide Tracer and Applied Pharmacokinetic Multiple Compartment Modeling	19
Development of a New Dry Powder Aerosol Synthetic Lung Surfactant Product for Neonatal Respiratory Distress Syndrome (RDS) – Part II: In vivo Efficacy Testing in a Rabbit Surfactant Washout Model	18
Numerical Investigation to Improve Pulmonary Drug Delivery via Dry Powder Inhalers: A Review of In-Silico Modeling	18
Optimization of Lung Surfactant Coating of siRNA Polyplexes for Pulmonary Delivery	18
Assessment of Minipigs as a Non-clinical Model for Screening and Derisking Injection Site Reactions in Clinical Trials	18
Ionic Liquids: Emerging Antimicrobial Agents	18
Microneedle-Mediated Permeation Enhancement of Chlorhexidine Digluconate: Mechanistic Insights Through Imaging Mass Spectrometry	18
Acetylcholine Analog-Modified Albumin Nanoparticles for the Enhanced and Synchronous Brain Delivery of Saponin Components of Panax Notoginseng	17
Coformer-Dependent Physical Stability in a Series of Naringenin-Based Coamorphous Materials with Caffeine, Theophylline, and Theobromine	17
Consideration of Fractional Distribution Parameter fd in the Chen and Gross Method for Tissue-to-Plasma Partition Coefficients: Comparison of Several Methods	17
N-oxidation Regioselectivity and Risk Prediction Using DFT-ALIE Calculations	17
In Vitro-In Vivo Correlation Of Amorphous Solid Dispersion Enabled Itraconazole Tablets	17
An Evaluation of Wet Granulation Process Selection for API Prone to Polymorphic Form Conversion in the Presence of Moisture and Heat	17
Differences in Pharmacokinetic/Pharmacodynamic Parameters of Tedizolid Against VRE and MRSA	16
A Semi-Physiological Three-Compartment Model Describes Brain Uptake Clearance and Efflux of Sucrose and Mannitol after IV Injection in Awake Mice	16
Efficient Cytosolic Delivery of siRNA Using Lyophilized and Reconstituted Polymer-siRNA Polyplexes	16
Impostor Phenomenon and Grit as Predictors of Job Satisfaction in Female Pharmacy Faculty	16
Convolutional Neural Networks Guided Raman Spectroscopy as a Process Analytical Technology (PAT) Tool for Monitoring and Simultaneous Prediction of Monoclonal Antibody Charge Variants	16
Application of Confocal Raman Microscopy for the Characterization of Topical Semisolid Formulations and their Penetration into Human Skin Ex Vivo	16
Development of a Physiologically-Based Pharmacokinetic Model for Whole-Body Disposition of MMAE Containing Antibody-Drug Conjugate in Mice	16
Pharmacokinetic Profile of Brepocitinib with Topical Administration in Atopic Dermatitis and Psoriasis Populations: Strategy to Inform Clinical Trial Design in Adult and Pediatric Populations	15
Spray Dried Rugose Lipid Particle Platform for Respiratory Drug Delivery	15
Development of an Accelerated Rotator-based Drug Release Method for the Evaluation of Bupivacaine Multivesicular Liposomes	15
Applications of Model Informed Drug Development (MIDD) in Drug Development Lifecycle and Regulatory Review	15
Polymorphism of Pradofloxacin: Crystal Structure Analysis, Stability Study, and Phase Transformation Behavior	15
Freeze-Dried Biopharmaceutical Formulations are Surprisingly Less Stable than Liquid Formulations during Dropping	15
Leveraging Model Master Files from a Technology Company Perspective: Facilitating Quantitative Medicine in Regulatory Frameworks	14
Development of a Once-Daily Modified-Release Formulation for the Short Half-Life RIPK1 Inhibitor GSK2982772 using DiffCORE Technology	14
A Hollow Microneedle Equipped with a Micropillar for Improved Needle Insertion and Injection of Drug Solution	14
Recent Update on Bacteria as a Delivery Carrier in Cancer Therapy: From Evil to Allies	14
Evaluation of Encequidar as An Intestinal P-gp and BCRP Specific Inhibitor to Assess the Role of Intestinal P-gp and BCRP in Drug-Drug Interactions	14
Enhancing the Stability, Solubility, and Antioxidant Activity of Cinchonine through Pharmaceutical Cocrystallization	14
Roles and Application of Extracellular Vesicles Occurring Endogenously and Naturally	14
Biodistribution and Non-linear Gene Expression of mRNA LNPs Affected by Delivery Route and Particle Size	14
Adopting the Model Master File Framework to Enhance Modeling and Simulations Approaches for Regulatory Use	14
Improvement of Workflows and Assay Reproducibility by The Introduction of “Assay-Ready” Culturing of MDCK Cells for Transport Studies	14
Co-delivery of Brinzolamide and Timolol from Micelles-laden Contact Lenses: In vitro and In Vivo Evaluation	14
Potential Application of Exosomes in Vaccine Development and Delivery	14
Aerosolizable Plasmid DNA Dry Powders Engineered by Thin-film Freezing	14
Characteristics of Tylvalosin Tartrate Enteric Amorphous Pellets Prepared by Liquid Layering	13
Development of Candesartan Cilexetil-sodium Carbonate Anhydrate-mesoporous Silica Solid Dispersion in Polymer-free System	13
Evaluation of Pharmacokinetic and Pharmacodynamic (PK/PD) of Novel Fluorenylmethoxycarbonyl- Phenylalanine Antimicrobial Agent	13
Mechanism of Insoluble Aggregate Formation in a Reconstituted Solution of Spray-Dried Protein Powder	13
Influence of Milling Parameters on Crystal Morphology, Thermal Behavior, and Dissolution of Mesalamine Nanocrystals	13
miRNA Signature of Urine Extracellular Vesicles Shows the Involvement of Inflammatory and Apoptotic Processes in Diabetic Chronic Kidney Disease	13
A New Analytical LC–MS/MS Method for Determination of Eight Standard Nitrosamines (NDMA, NMBA, NDEA, NEIPA, NDIPA, NMPA, NDPA, NDBA) in a Commercial Small Molecule Drug Product Capsules and its Active	13
Incorporating Uremic Solute-mediated Inhibition of OAT1/3 Improves PBPK Prediction of Tenofovir Renal and Systemic Disposition in Patients with Severe Kidney Disease	12
Direct Assessment of Oligomerization of Chemically Modified Peptides and Proteins in Formulations using DLS and DOSY-NMR	12
Preclinical Toxicity Study and Tissue Distribution of YSCH- 01 Injection via Intratumoral Injection, Intravenous Injection, and Intraperitoneal Injection in Syrian Hamsters	12
Meta-Analysis of Drug Delivery Approaches for Treating Intracellular Infections	12
Discovery of the Next Generation of Non-peptidomimetic Neurolysin Activators with High Blood-Brain Barrier Permeability: a Pharmacokinetics Study in Healthy and Stroke Animals	12
Critical Needs and Opportunities for Advanced Manufacturing of Lyophilized Injectables	12
Research Landscape of Physiologically Based Pharmacokinetic Model Utilization in Different Fields: A Bibliometric Analysis (1999–2023)	12
Cefmetazole as an Alternative to Carbapenems Against Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Infections Based on In Vitro and In Vivo Pharmacokinetics/Pharmacodynamics Experiments	12
Physiologically Based Pharmacokinetic Modeling for Prediction of 5-FU Pharmacokinetics in Cancer Patients with Hepatic Impairment After 5-FU and Capecitabine Administration	12
Retraction Note: Combination Cancer Immunotherapy with Dendritic Cell Vaccine and Nanoparticles Loaded with Interleukin-15 and Anti-beta-catenin siRNA Significantly Inhibits Cancer Growth and Induces	12
Dissolution Profiles of Carbamazepine Cocrystals with Cis–Trans Isomeric Coformers	12
Correlative Image-Based Release Prediction and 3D Microstructure Characterization for a Long Acting Parenteral Implant	12
Reference Standards to Support Quality of Synthetic Peptide Therapeutics	12
Modeling Multiphase Heat and Mass Transfer in an Agitated Filter Dryer by Integrating Experiment, Computations, and Analytical Solutions	12
Inhalable N-Acetylcysteine-loaded Lactose-coated PLGA Nanoparticles for Tuberculosis Treatment	12
Retraction Note to: Nanoformulation of Apolipoprotein E3-Tagged Liposomal Nanoparticles for the Co-Delivery of KRAS-siRNA and Gemcitabine for Pancreatic Cancer Treatment	12
Impact of Select Geometric and Operational Parameters on Hydrodynamics in Dissolution Apparatus 2 (Paddle Apparatus): A Design of Experiments Analysis Based on Computational Fluid Dynamics Simulations	12
Minimal Physiologically-based Pharmacokinetic Model to Investigate the Effect of Charge on the Pharmacokinetics of Humanized anti-HCV-E2 IgG Antibodies in Sprague–Dawley Rats	11
Validation of Anti-Adeno Associated Virus Serotype rh10 (AAVrh.10) Total and Neutralizing Antibody Immunogenicity Assays	11
Structure and Function of Cationic and Ionizable Lipids for Nucleic Acid Delivery	11
Raman Spectroscopic Analysis of Highly-Concentrated Antibodies under the Acid-Treated Conditions	11
Novel Self-Assembled Micelles With Increased Tumor Penetration and Anti-Tumor Efficiency Against Breast Cancer	11
Midazolam Infusion and Disease Severity Affect the Level of Sedation in Children: A Parametric Time-to-Event Analysis	11

Directing the Way—Receptor and Chemical Targeting Strategies for Nucleic Acid Delivery	11
Scaling Down Large-Scale Thawing of Monoclonal Antibody Solutions: 3D Temperature Profiles, Changes in Concentration, and Density Gradients	11
Use of Flory–Huggins Interaction Parameter and Contact Angle Values to Predict the Suitability of the Drug-Polymer System for the Production and Stability of Nanosuspensions	11
Identification of the specific causes of polysorbate 20 degradation in monoclonal antibody formulations containing multiple lipases	11
Correction: Practical Advice on Scientific Design of Freeze-Drying Process: 2023 Update	11
Dissolution Profiles Comparison Using Various Model Independent Statistical Approaches: Can We Increase Chance of Similarity?	11
Evaluation of Two Cosolvency Models to Predict Solute Partitioning between Polymers (LDPE) and Water - Ethanol Simulating Solvent Mixtures	11
Dextran Mass Ratio Controls Particle Drying Dynamics in a Thermally Stable Dry Powder Vaccine for Pulmonary Delivery	11
Rapid Development of High Concentration Protein Formulation Driven by High-Throughput Technologies	11
The Impact of Post-Processing Temperature on PLGA Microparticle Properties	11
Evaluation of In Vitro Metabolism- and Transporter-Based Drug Interactions with Sunscreen Active Ingredients	11
An Enthalpy-Balance Model for Timewise Evolution of Temperature during Wet Stirred Media Milling of Drug Suspensions	11
Osmolality of Excipients for Parenteral Formulation Measured by Freezing Point Depression and Vapor Pressure – A Comparative Analysis	11
Strategies to improve the physicochemical properties of peptide-based drugs	11
The Acute Impact of Propofol on Blood–Brain Barrier Integrity in Mice	11
Translation from Preclinical Research to Clinical Trials: Transdermal Drug Delivery for Neurodegenerative and Mental Disorders	10
Olmesartan niosomes ameliorates the Indomethacin-induced gastric ulcer in rats: Insights on MAPK and Nrf2/HO-1 signaling pathway	10
Co-delivery of gemcitabine and cisplatin via Poly (L-glutamic acid)-g-methoxy poly (ethylene glycol) micelle to improve the in vivo stability and antitumor effect	10
The Role of Artificial Intelligence and Machine Learning in Accelerating the Discovery and Development of Nanomedicine	10
Effect of Buffer Salts on Physical Stability of Lyophilized and Spray-Dried Protein Formulations Containing Bovine Serum Albumin and Trehalose	10
Shedding Light on the Blood–Brain Barrier Transport with Two-Photon Microscopy In Vivo	10
Effect of Particle Size and Surface Charge on Nanoparticles Diffusion in the Brain White Matter	10
Sialic Acid-based Glycoconjugation on Myricetin-encapsulated Cationic Nanocarriers for the Treatment of Alzheimer's	10
Effect of Structurally Related Compounds on Desupersaturation Kinetics of Indomethacin	10
Correction: Leveraging Model Master Files for Long-Acting Injectables	10
Solubility vs Dissolution in Physiological Bicarbonate Buffer	10
A Novel Fluoro-Pyrazine-Bridged Donor-Accepter-Donor Fluorescent Probe for Lipid Droplet-Specific Imaging in Diverse Cells and Superoxide Anion Generation	10
Strategies to Stabilize Dalbavancin in Aqueous Solutions; Section-1: the Effects of Metal Ions and Buffers	10
Correction: Effect of Buffer Salts on Physical Stability of Lyophilized and Spray-Dried Protein Formulations Containing Bovine Serum Albumin and Trehalose	10
In Vitro ADME and Preclinical Pharmacokinetics of Ulotaront, a TAAR1/5-HT1A Receptor Agonist for the Treatment of Schizophrenia	10
High Content Image Analysis of Cellular Responses of the Murine J774A.1 Cell Line and Primary Human Cells Alveolar Macrophages to an Extended Panel of Pharmaceutical Agents	10
Enabling Efficient Design of Biological Formulations through Advanced Characterizations	10
Role of Tissue Hydraulic Permeability in Convection-Enhanced Delivery of Nanoparticle-Encapsulated Chemotherapy Drugs to Brain Tumour	10
In vivo Pharmacokinetic/Pharmacodynamic Analysis of the Efficacy of the Cefepime/Nacubactam Combination Against β-Lactamase-Producing Enterobacterales based on the Instantaneous MIC Concept	10
Pharmacokinetic Modeling of the Effect of Tariquidar on Ondansetron Disposition into the Central Nervous System	10
Single-dose pharmacokinetics and lung function of nebulized niclosamide ethanolamine in sheep	9
Trends in Light and Temperature Sensitivity Recommendations among Licensed Biotechnology Drug Products	9
Physiologically Based Pharmacokinetic Model of Brain Delivery of Plasma Protein Bound Drugs	9
Mathematical and Pharmacokinetic Approaches for the Design of New 3D Printing Inks Using Ricobendazole	9
Chemical Distribution Uniformity Assessment of “Intra-Tablet” by Hyperspectral Raman Imaging Analysis	9
Predicting Drug-Drug Interactions Involving Rifampicin Using a Semi-mechanistic Hepatic Compartmental Model	9
Translational Modeling Identifies Synergy between Nanoparticle-Delivered miRNA-22 and Standard-of-Care Drugs in Triple-Negative Breast Cancer	9
Can Extracellular Vesicles as Drug Delivery Systems Be a Game Changer in Cardiac Disease?	9
Physiologically Based Biopharmaceutics Model for Selumetinib Food Effect Investigation and Capsule Dissolution Safe Space – Part I: Adults	9
Challenges and Opportunities for Celecoxib Repurposing	9
Intradermal Vaccination with PLGA Nanoparticles via Dissolving Microneedles and Classical Injection Needles	9
Optimisation of Pharmaceutical Cocrystal Dissolution Performance through a Synergistic Precipitation Inhibition	9
Inhaled Indomethacin-Loaded Liposomes as Potential Therapeutics against Non-Small Cell Lung Cancer (NSCLC)	9
Vehicles for Drug Administration to Children: Results and Learnings from an In-Depth Screening of FDA-Recommended Liquids and Soft Foods for Product Quality Assessment	9
Lipid Microparticles Show Similar Efficacy With Lipid Nanoparticles in Delivering mRNA and Preventing Cancer	9
Microneedle Mediated Iontophoretic Delivery of Tofacitinib Citrate	9
Effects of Intradermal Administration Volume Using a Hollow Microneedle on the Pharmacokinetics of Fluorescein Isothiocyanate Dextran (M.W. 4,000)	9
Clinical Investigation of Large Volume Subcutaneous Delivery up to 25 mL for Lean and Non-Lean Subjects	9
Assessment of Escherichia coli-derived Recombinant Human Bone Morphogenic Protein-2 on Fertilization and Early Embryonic Development in Rats	9
Revisiting the Effect of Aging on the Transport of Molecules through the Skin	9
Mechanisms of Crystal Plasticization by Lattice Water	9
Characterization of mRNA Lipid Nanoparticles by Electron Density Mapping Reconstruction: X-ray Scattering with Density from Solution Scattering (DENSS) Algorithm	9
In-Vivo Tape Stripping Study with Caffeine for Comparisons on Body Sites, Age and Washing	8
Assessment of High-Power Electronic Nicotine Delivery System as an Alternative Aerosol Device for Terbutaline Delivery	8
Hollow MnO2-Based Nanoprobes for Enhanced Photothermal/Photodynamic /Chemodynamic Co-Therapy of Hepatocellular Carcinoma	8
Modeling Dual Drug Delivery from Eluting Stents: The Influence of Non-Linear Binding Competition and Non-Uniform Drug Loading	8
Identification of Four Similar Cell Culture Media According to their Glucose, Glutamine, and Pyruvate Content by Handheld Raman Spectroscopy	8
Susceptibility of Lung Carcinoma Cells to Nanostructured Lipid Carrier of ARV-825, a BRD4 Degrading Proteolysis Targeting Chimera	8
A Reference Standard for Analytical Testing of Erythropoietin	8
3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter Exploration Via Computational Fluid Dynamics Simulation	8
Pharmacological Innovations in Space: Challenges and Future Perspectives	8
Effect of “In Use” Administration on Topical Product Metamorphosis and Skin Permeation of Acyclovir Creams: Implications for Bioequivalence	8
The Impact of Drug Properties and Severity of Obesity on Renal Drug Clearance Through Glomerular Filtration and Active Tubular Secretion: A Systematic Analysis Using PBPK Modeling	8
Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy	8
In-Silico Modelling of Transdermal Delivery of Macromolecule Drugs Assisted by a Skin Stretching Hypobaric Device	8
Quantum Cascade Laser Based Infrared Spectroscopy: A New Paradigm for Protein Secondary Structure Measurement	8
Berberine Improves the Protective Effects of Metformin on Diabetic Nephropathy in db/db Mice through Trib1-dependent Inhibiting Inflammation	8
Evaluation of the Combination of L‑leucine to Chitosan on Sustained Release of Inhalable Heparin Sodium Microparticles	8
Finite Element Modeling of Powder Compaction: Mini-Tablets in Comparison with Conventionally Sized Tablets	8
Pre-clinical Formulation Development of an in situ Meglumine Salt of AZD5991: A Novel Macrocyclic Mcl-1 Inhibitor	8
Comparative Thermodynamics of the Reversible Self-Association of Therapeutic mAbs Reveal Opposing Roles for Linked Proton- and Ion-Binding Events	8
Applications of Model-Based Meta-Analysis in Drug Development	8
In vitro Dissolution Testing of Rifampicin Powder Formulations For Prediction of Plasma Concentration–Time Profiles After Inhaled Delivery	8
The Extension of the LeiCNS-PK3.0 Model in Combination with the “Handshake” Approach to Understand Brain Tumor Pathophysiology	8
Characterization of Grinding-Induced Subvisible Particles and Free Radicals in a Freeze-Dried Monoclonal Antibody Formulation	7
Enhancing the Cellular Production of Extracellular Vesicles for Developing Therapeutic Applications	7
Considerations for Regulatory Reusability of Dynamic Tools in the New Drug Development	7
Improving the Manufacturability of Cohesive and Poorly Compactable API for Direct Compression of Mini-tablets at High Drug Loading via Particle Engineering	7
Risk Assessment for a Twin-Screw Granulation Process Using a Supervised Physics-Constrained Auto-encoder and Support Vector Machine Framework	7
Functional Evaluation of P-gp and Bcrp at the Murine Blood-Cerebrospinal Fluid Barrier	7
Fabrication of Uniform Melatonin Microparticles Potentially for Nasal Delivery: A Comparison of Spray Drying and Spray Freeze Drying	7
The Research Progress of Metformin Regulation of Metabolic Reprogramming in Malignant Tumors	7
The Effects of Solid Particle Containing Inks on the Printing Quality of Porous Pharmaceutical Structures Fabricated by 3D Semi-Solid Extrusion Printing	7
Combined Treatment of Metformin and Resveratrol Promotes Myogenesis Through Increased Irisin Release in C2C12 Cells	7
Expanding the toolbox for predictive parameters describing antibody stability considering thermodynamic and kinetic determinants	7
Drug complexes: Perspective from Academic Research and Pharmaceutical Market	7
Repurposing an Antiepileptic Drug for the Treatment of Glioblastoma	7
An In Vitro Dissolution Method for Inhaled Drugs Depositing in the Tracheobronchial Lung Region	7
Impact of Formulation and Microneedle Length on Transdermal Metronidazole Permeation through Microneedle-Treated Skin	7
Selection of Silica Type and Amount for Flowability Enhancements via Dry Coating: Contact Mechanics Based Predictive Approach	7