Pharmaceutical Research

Article	Citations
Combating Alcohol Adduct Impurity in Immunosuppressant Drug Product Manufacturing: A Scientific Investigation for Enhanced Process Control	166
Thermo-Responsive Polymer-siRNA Conjugates Enabling Artificial Control of Gene Silencing around Body Temperature	159
Analytical Workflows to Unlock Predictive Power in Biotherapeutic Developability	127
Modeling Gasotransmitter Availability to Brain Capillary Endothelial Cells with Ultrasound-sensitive Microbubbles	105
Drug Release from Surfactant-Containing Amorphous Solid Dispersions: Mechanism and Role of Surfactant in Release Enhancement	88
Effect of Fatty Acid Composition in Polysorbate 80 on the Stability of Therapeutic Protein Formulations	81
Discovery and Control of Succinimide Formation and Accumulation at Aspartic Acid Residues in The Complementarity-Determining Region of a Therapeutic Monoclonal Antibody	78
Ritonavir-Boosted Exposure of Kinase Inhibitors: an Open Label, Cross-over Pharmacokinetic Proof-of-Concept Trial with Erlotinib	67
Safety and Pharmacokinetics of Intranasally Administered Heparin	63
Novel Deep Eutectic Solvent–Hydrogel Systems for Synergistic Transdermal Delivery of Chinese Herb Medicine and Local Treatments for Rheumatoid Arthritis	61
Pharmacokinetic Assessment of Drug Efflux from Erythrocytes Loaded with Corticosteroid Esters	54
Cationic Ester Prodrugs of Curcumin with N,N-dimethyl Amino Acid Promoieties Improved Poor Water Solubility and Intestinal Absorption	51
Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice	48
Computational and Experimental Screening Approaches to Aripiprazole Salt Crystallization	47
Brain Targeted Curcumin Loaded Turmeric Oil Microemulsion Protects Against Trimethyltin Induced Neurodegeneration in Adult Zebrafish: A Pharmacokinetic and Pharmacodynamic Insight	43
Engineering a Remedy to Modulate and Optimize Biopharmaceutical Properties of Rebamipide by Synthesizing New Cocrystal: In Silico and Experimental Studies	42
Unambiguous Identification of Glucose-Induced Glycation in mAbs and other Proteins by NMR Spectroscopy	42
Perspectives on the Wetting of Solids in Pharmaceutical Systems	40
In Vitro and In Silico Investigations on Drug Delivery in the Mouth-Throat Models with Handihaler®	40
Relative Performance of Volume of Distribution Prediction Methods for Lipophilic Drugs with Uncertainty in LogP Value	39
Development of Amorphous Solid Dispersion Sustained-Release Formulations with Polymer Composite Matrix-Regulated Stable Release Plateaus	39
Professor Margareta Hammarlund-Udenaes – a Modern and Visionary Mentor	38
Limited Impact of Murine Placental MDR1 on Fetal Exposure of Certain Drugs Explained by Bypass Transfer Between Adjacent Syncytiotrophoblast Layers	38
RETRACTED ARTICLE: Characterization of Preclinical Pharmacokinetic Properties and Prediction of Human PK Using a Physiologically Based Pharmacokinetic Model for a Novel Anti-Arrhythmic Agent Sulcardin	37
Utilizing Octanoic Acid to Quantitatively Assess the Oxidation Status of PS80	36

Micafungin Population PK Analysis in Healthy and Septic Pigs: Can the Septic Porcine Model Predict the Micafungin PK in Septic Patients?	36
Revolutionizing Heart Failure Therapy: Harnessing IVT mRNA and Fusion Protein Technology to Prolong rhBNP Half-Life	35
Cortisol as Biomarker for CYP17-Inhibition is Associated with Therapy Outcome of Abiraterone Acetate	35
Correction: A Preformulation Experiment: The Influence of Poloxamer 188 and Poloxamer 407 on the Binding Coefficients (Single Molecule) and the Partitioning Coefficients (Micelle) of Ketoprofen (Probe	34
PEGylation of Propofol Reduces Its Adsorption to Extracorporeal Membrane Oxygenator (ECMO) Components	34
Controlling Gastric Delivery of a GIP/GLP1 Peptide in Monkeys by Mucoadhesive SNAC Tablets	34
Photo-Oxidation Mechanisms in Liquid Pharmaceutical Formulations: The Overlooked Role of Singlet Oxygen Presented as a Case Study	33
Learning Chemotherapy Drug Action via Universal Physics-Informed Neural Networks	33
Delivery of Corn-Derived Nanoparticles with Anticancer Activity to Tumor Tissues by Modification with Polyethylene Glycol for Cancer Therapy	33
Advancements in Particle Engineering for Inhalation Delivery of Small Molecules and Biotherapeutics	33
Therapeutic Potential of Semaglutide, a Newer GLP-1 Receptor Agonist, in Abating Obesity, Non-Alcoholic Steatohepatitis and Neurodegenerative diseases: A Narrative Review	33
Coupling Drug Dissolution with BCS	33
Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells	33
Role of Disease Progression Models in Drug Development	33
Enhanced Penetration and Retention of an Antibody in the Articular Cartilage Through Aggrecan Binding and Molecular Downsizing	32
Design of an Ante-enhancer with an Azone-Mimic Structure using Ionic Liquid	31
A Novel Combination Therapy of Erythropoietin and Thrombopoietin to Treat Erythropoietin-Resistance anemia	31
Editorial Expression of Concern: Regulation of miR-19 to Breast Cancer Chemoresistance Through Targeting PTEN	31
Phase Transitions Involving Channel Hydrates of a New Pharmaceutical Compound	30
Improved Pharmaceutical Properties of Honokiol via Salification with Meglumine: an Exception to Oft-quoted ∆pKa Rule	30
Model-Guided Development of a Semi-Continuous Drying Process	30
PAMAM versus PEI complexation for siRNA delivery: interaction with model lipid membranes and cellular uptake	30
Novel Pharmaceutical Cocrystals of Tegafur: Synthesis, Performance, and Theoretical Studies	29
Peptide Acylation in Aliphatic Polyesters: a Review of Mechanisms and Inhibition Strategies	29
Generic Enrichment Method for Liquid Chromatography-Multiple Reaction Monitoring-Mass Spectrometry Assay for Quantitative Measurement of Biological Therapeutics in Serum	28
Modification of Peptide and Permeation Enhancer In Vitro Release Rates by Dispersion with a Gel-Forming Polymer	28
Design Considerations for Intratracheal Delivery Devices to Achieve Proof-of-Concept Dry Powder Biopharmaceutical Delivery in Mice	28
Multiphysics Modelling and Simulation of Thrombolysis via Activated Platelet-Targeted Nanomedicine	28
Temperature and Heat Transfer Control During Freeze Drying. Effect of Vial Holders and Influence of Pressure	28
Physiologically-Based Pharmacokinetic Modeling of PAXLOVID™ with First-Order Absorption Kinetics	27
Investigation of an Uncommon Artifact during Reducing Capillary Electrophoresis-Sodium Dodecyl Sulfate Analysis of a Monoclonal Antibody with Dynamic Light Scattering and Reversed Phase High-Performan	27
Strategy for Cytoplasmic Delivery Using Inorganic Particles	26
Topical Semisolid Drug Product Critical Quality Attributes with Relevance to Cutaneous Bioavailability and Pharmacokinetics: Part I—Bioequivalence of Acyclovir Topical Creams	26
Oral Delivery of Nucleic Acid Therapies for Local and Systemic Action	26
N-terminus of Etanercept is Proteolytically Processed by Dipeptidyl Peptidase-4	25
Elucidating the Impact of Material Properties on Tablet Manufacturability for Binary Paracetamol Blends	25
Correction to: Re-examining digoxin bioavailability after half a century: Time for changes in the bioavailability concepts	25
Microdialysis of Drug and Drug Metabolite: a Comprehensive In Vitro Analysis for Voriconazole and Voriconazole N-oxide	25
Retraction Note: Characterization of Preclinical Pharmacokinetic Properties and Prediction of Human PK Using a Physiologically Based Pharmacokinetic Model for a Novel Anti-Arrhythmic Agent Sulcardine	25
Optimization of Vancomycin Initial Dose in Term and Preterm Neonates by Machine Learning	25
Formulation and Validation of an Extended Sigmoid Emax Model in Pharmacodynamics	24
Evaluation of Blood-CSF Barrier Transport by Quantitative Real Time Fluorescence Microscopy	24
Decrease in In Vivo Efflux Transport via P-glycoprotein at the Rat Inner Blood-Retinal Barrier by Peripheral Administration of Lipopolysaccharide	24
Sensitivity and Uncertainty Analysis of Micro-Flow Imaging for Sub-Visible Particle Measurements Using Artificial Neural Network	23
Application of Twin-Screw Melt Granulation to Overcome the Poor Tabletability of a High Dose Drug	23
Progress in the Application of Microneedles in Eye Disorders and the Proposal of the Upgraded Microneedle with Spinule	23
Development and Evaluation of Dual Microneedle Array Patch for Sequential Intradermal Delivery of Adjuvant and Antigen	23
Dissolution Profiles of Poorly Soluble Drug Salts in Bicarbonate Buffer	23
The Osmolality and Hemolysis of High-Concentration Monoclonal Antibody Formulations	23
Predictive Value of Vancomycin AUC24/MIC Ratio for 30-day Mortality in Patients with Severe or Complicated Methicillin-Resistant Staphylococcus aureus Infections: A Multicenter Retrospective Study	22

Application of PAT Probes in Aluminum Phosphate Adjuvant Manufacturing	22
Hydration Mechanism and Its Effect on the Solubility of Aripiprazole	22
Nanobody-Oligonucleotide Conjugates (NucleoBodies): The Next Frontier in Oligonucleotide Therapy	22
Time-Lapse Macro Imaging with Dissolution Tests for Exploring the Interrelationship Between Disintegration and Dissolution Behaviors of Solid Dosages	21
Correction to: Liposomal Formulation for Oral Delivery of Cyclosporine A: Usefulness as a Semisolid-Dispersion System	21
Development of a Physiologically-Based Pharmacokinetic Model for Whole-Body Disposition of MMAE Containing Antibody-Drug Conjugate in Mice	21
A Model-Based Evaluation of Noninvasive Biomarkers to Reflect Histological Nonalcoholic Fatty Liver Disease Scores	20
Local Delivery of Non-opioid Analgesic Microparticles to Modulate Post-surgical Pain	20
Convolutional Neural Networks Guided Raman Spectroscopy as a Process Analytical Technology (PAT) Tool for Monitoring and Simultaneous Prediction of Monoclonal Antibody Charge Variants	20
An Evaluation of Wet Granulation Process Selection for API Prone to Polymorphic Form Conversion in the Presence of Moisture and Heat	20
Coformer-Dependent Physical Stability in a Series of Naringenin-Based Coamorphous Materials with Caffeine, Theophylline, and Theobromine	20
Impostor Phenomenon and Grit as Predictors of Job Satisfaction in Female Pharmacy Faculty	20
Optimization of Lung Surfactant Coating of siRNA Polyplexes for Pulmonary Delivery	19
Differences in Pharmacokinetic/Pharmacodynamic Parameters of Tedizolid Against VRE and MRSA	19
Numerical Investigation to Improve Pulmonary Drug Delivery via Dry Powder Inhalers: A Review of In-Silico Modeling	19
Microneedle-Mediated Permeation Enhancement of Chlorhexidine Digluconate: Mechanistic Insights Through Imaging Mass Spectrometry	19
Efficient Cytosolic Delivery of siRNA Using Lyophilized and Reconstituted Polymer-siRNA Polyplexes	19
Assessment of Minipigs as a Non-clinical Model for Screening and Derisking Injection Site Reactions in Clinical Trials	19
Application of Confocal Raman Microscopy for the Characterization of Topical Semisolid Formulations and their Penetration into Human Skin Ex Vivo	18
In Vitro-In Vivo Correlation Of Amorphous Solid Dispersion Enabled Itraconazole Tablets	18
Consideration of Fractional Distribution Parameter fd in the Chen and Gross Method for Tissue-to-Plasma Partition Coefficients: Comparison of Several Methods	18
Accelerating Process Development and Product Formulation	18
Development of a New Dry Powder Aerosol Synthetic Lung Surfactant Product for Neonatal Respiratory Distress Syndrome (RDS) – Part II: In vivo Efficacy Testing in a Rabbit Surfactant Washout Model	18
A Semi-Physiological Three-Compartment Model Describes Brain Uptake Clearance and Efflux of Sucrose and Mannitol after IV Injection in Awake Mice	17
Understanding the Phagocytosis of Particles: the Key for Rational Design of Vaccines and Therapeutics	17
Ionic Liquids: Emerging Antimicrobial Agents	17
Acetylcholine Analog-Modified Albumin Nanoparticles for the Enhanced and Synchronous Brain Delivery of Saponin Components of Panax Notoginseng	17
Fluorinated PAMAM-Arginine Carrier Prodrugs for pH-Sensitive Sustained Ibuprofen Delivery	17
N-oxidation Regioselectivity and Risk Prediction Using DFT-ALIE Calculations	17
Freeze-Dried Biopharmaceutical Formulations are Surprisingly Less Stable than Liquid Formulations during Dropping	16
Adopting the Model Master File Framework to Enhance Modeling and Simulations Approaches for Regulatory Use	16
Leveraging Model Master Files from a Technology Company Perspective: Facilitating Quantitative Medicine in Regulatory Frameworks	16
Applications of Model Informed Drug Development (MIDD) in Drug Development Lifecycle and Regulatory Review	16
A Hollow Microneedle Equipped with a Micropillar for Improved Needle Insertion and Injection of Drug Solution	15
Aerosolizable Plasmid DNA Dry Powders Engineered by Thin-film Freezing	15
Improvement of Workflows and Assay Reproducibility by The Introduction of “Assay-Ready” Culturing of MDCK Cells for Transport Studies	15
Development of a Once-Daily Modified-Release Formulation for the Short Half-Life RIPK1 Inhibitor GSK2982772 using DiffCORE Technology	15
miRNA Signature of Urine Extracellular Vesicles Shows the Involvement of Inflammatory and Apoptotic Processes in Diabetic Chronic Kidney Disease	15
Enhancing the Stability, Solubility, and Antioxidant Activity of Cinchonine through Pharmaceutical Cocrystallization	15
Development of an Accelerated Rotator-based Drug Release Method for the Evaluation of Bupivacaine Multivesicular Liposomes	15
Pharmacokinetic Profile of Brepocitinib with Topical Administration in Atopic Dermatitis and Psoriasis Populations: Strategy to Inform Clinical Trial Design in Adult and Pediatric Populations	15
Potential Application of Exosomes in Vaccine Development and Delivery	15
Roles and Application of Extracellular Vesicles Occurring Endogenously and Naturally	15
Co-delivery of Brinzolamide and Timolol from Micelles-laden Contact Lenses: In vitro and In Vivo Evaluation	15
Evaluation of Encequidar as An Intestinal P-gp and BCRP Specific Inhibitor to Assess the Role of Intestinal P-gp and BCRP in Drug-Drug Interactions	15
Polymorphism of Pradofloxacin: Crystal Structure Analysis, Stability Study, and Phase Transformation Behavior	15
Recent Update on Bacteria as a Delivery Carrier in Cancer Therapy: From Evil to Allies	15
Spray Dried Rugose Lipid Particle Platform for Respiratory Drug Delivery	15
Characteristics of Tylvalosin Tartrate Enteric Amorphous Pellets Prepared by Liquid Layering	14
Retraction Note to: Nanoformulation of Apolipoprotein E3-Tagged Liposomal Nanoparticles for the Co-Delivery of KRAS-siRNA and Gemcitabine for Pancreatic Cancer Treatment	14
Research Landscape of Physiologically Based Pharmacokinetic Model Utilization in Different Fields: A Bibliometric Analysis (1999–2023)	14
Physiologically Based Pharmacokinetic Modeling for Prediction of 5-FU Pharmacokinetics in Cancer Patients with Hepatic Impairment After 5-FU and Capecitabine Administration	14
Meta-Analysis of Drug Delivery Approaches for Treating Intracellular Infections	14
Retraction Note: Combination Cancer Immunotherapy with Dendritic Cell Vaccine and Nanoparticles Loaded with Interleukin-15 and Anti-beta-catenin siRNA Significantly Inhibits Cancer Growth and Induces	14
Evaluation of Pharmacokinetic and Pharmacodynamic (PK/PD) of Novel Fluorenylmethoxycarbonyl- Phenylalanine Antimicrobial Agent	14
Biodistribution and Non-linear Gene Expression of mRNA LNPs Affected by Delivery Route and Particle Size	14
Discovery of the Next Generation of Non-peptidomimetic Neurolysin Activators with High Blood-Brain Barrier Permeability: a Pharmacokinetics Study in Healthy and Stroke Animals	14
Preclinical Toxicity Study and Tissue Distribution of YSCH- 01 Injection via Intratumoral Injection, Intravenous Injection, and Intraperitoneal Injection in Syrian Hamsters	14
Validation of Anti-Adeno Associated Virus Serotype rh10 (AAVrh.10) Total and Neutralizing Antibody Immunogenicity Assays	14
Structure and Function of Cationic and Ionizable Lipids for Nucleic Acid Delivery	13
An Enthalpy-Balance Model for Timewise Evolution of Temperature during Wet Stirred Media Milling of Drug Suspensions	13
Modeling Multiphase Heat and Mass Transfer in an Agitated Filter Dryer by Integrating Experiment, Computations, and Analytical Solutions	13
A New Analytical LC–MS/MS Method for Determination of Eight Standard Nitrosamines (NDMA, NMBA, NDEA, NEIPA, NDIPA, NMPA, NDPA, NDBA) in a Commercial Small Molecule Drug Product Capsules and its Active	13
Use of Flory–Huggins Interaction Parameter and Contact Angle Values to Predict the Suitability of the Drug-Polymer System for the Production and Stability of Nanosuspensions	13
Impact of Select Geometric and Operational Parameters on Hydrodynamics in Dissolution Apparatus 2 (Paddle Apparatus): A Design of Experiments Analysis Based on Computational Fluid Dynamics Simulations	13
Incorporating Uremic Solute-mediated Inhibition of OAT1/3 Improves PBPK Prediction of Tenofovir Renal and Systemic Disposition in Patients with Severe Kidney Disease	13
Cefmetazole as an Alternative to Carbapenems Against Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Infections Based on In Vitro and In Vivo Pharmacokinetics/Pharmacodynamics Experiments	13
Correlative Image-Based Release Prediction and 3D Microstructure Characterization for a Long Acting Parenteral Implant	13
Mechanism of Insoluble Aggregate Formation in a Reconstituted Solution of Spray-Dried Protein Powder	13
Development of Candesartan Cilexetil-sodium Carbonate Anhydrate-mesoporous Silica Solid Dispersion in Polymer-free System	13
Identification of the specific causes of polysorbate 20 degradation in monoclonal antibody formulations containing multiple lipases	13
Dissolution Profiles of Carbamazepine Cocrystals with Cis–Trans Isomeric Coformers	13
Inhalable N-Acetylcysteine-loaded Lactose-coated PLGA Nanoparticles for Tuberculosis Treatment	13
Influence of Milling Parameters on Crystal Morphology, Thermal Behavior, and Dissolution of Mesalamine Nanocrystals	12
The Impact of Post-Processing Temperature on PLGA Microparticle Properties	12
In vivo Pharmacokinetic/Pharmacodynamic Analysis of the Efficacy of the Cefepime/Nacubactam Combination Against β-Lactamase-Producing Enterobacterales based on the Instantaneous MIC Concept	12
Novel Self-Assembled Micelles With Increased Tumor Penetration and Anti-Tumor Efficiency Against Breast Cancer	12
Minimal Physiologically-based Pharmacokinetic Model to Investigate the Effect of Charge on the Pharmacokinetics of Humanized anti-HCV-E2 IgG Antibodies in Sprague–Dawley Rats	12
Direct Assessment of Oligomerization of Chemically Modified Peptides and Proteins in Formulations using DLS and DOSY-NMR	12
Evaluation of In Vitro Metabolism- and Transporter-Based Drug Interactions with Sunscreen Active Ingredients	12

Solubility vs Dissolution in Physiological Bicarbonate Buffer	12
Correction: Practical Advice on Scientific Design of Freeze-Drying Process: 2023 Update	12
Reference Standards to Support Quality of Synthetic Peptide Therapeutics	12
Critical Needs and Opportunities for Advanced Manufacturing of Lyophilized Injectables	12
Evaluation of Two Cosolvency Models to Predict Solute Partitioning between Polymers (LDPE) and Water - Ethanol Simulating Solvent Mixtures	12
Dissolution Profiles Comparison Using Various Model Independent Statistical Approaches: Can We Increase Chance of Similarity?	12
Preclinical Evaluation of AAV8-R338L Gene Therapy for Hemophilia: Efficacy, Pharmacokinetics, Distribution, Excretion and Toxicity in Mouse Models and Non-human Primates	11
Pharmacokinetic Modeling of the Effect of Tariquidar on Ondansetron Disposition into the Central Nervous System	11
Rapid Development of High Concentration Protein Formulation Driven by High-Throughput Technologies	11
Correction: Effect of Buffer Salts on Physical Stability of Lyophilized and Spray-Dried Protein Formulations Containing Bovine Serum Albumin and Trehalose	11
Directing the Way—Receptor and Chemical Targeting Strategies for Nucleic Acid Delivery	11
Role of Tissue Hydraulic Permeability in Convection-Enhanced Delivery of Nanoparticle-Encapsulated Chemotherapy Drugs to Brain Tumour	11
Impact of Pre-Actuation Shaking on the Aerosolization Performance of Easyhaler® Salbutamol Dry Powder Inhaler	11
Osmolality of Excipients for Parenteral Formulation Measured by Freezing Point Depression and Vapor Pressure – A Comparative Analysis	11
Raman Spectroscopic Analysis of Highly-Concentrated Antibodies under the Acid-Treated Conditions	11
Effect of Particle Size and Surface Charge on Nanoparticles Diffusion in the Brain White Matter	11
Enabling Efficient Design of Biological Formulations through Advanced Characterizations	11
Strategies to improve the physicochemical properties of peptide-based drugs	11
Co-delivery of gemcitabine and cisplatin via Poly (L-glutamic acid)-g-methoxy poly (ethylene glycol) micelle to improve the in vivo stability and antitumor effect	11
Scaling Down Large-Scale Thawing of Monoclonal Antibody Solutions: 3D Temperature Profiles, Changes in Concentration, and Density Gradients	11
Dextran Mass Ratio Controls Particle Drying Dynamics in a Thermally Stable Dry Powder Vaccine for Pulmonary Delivery	11
Effect of Buffer Salts on Physical Stability of Lyophilized and Spray-Dried Protein Formulations Containing Bovine Serum Albumin and Trehalose	11
The Role of Artificial Intelligence and Machine Learning in Accelerating the Discovery and Development of Nanomedicine	11
Effect of Structurally Related Compounds on Desupersaturation Kinetics of Indomethacin	11
The Acute Impact of Propofol on Blood–Brain Barrier Integrity in Mice	11
Translation from Preclinical Research to Clinical Trials: Transdermal Drug Delivery for Neurodegenerative and Mental Disorders	11
A Novel Fluoro-Pyrazine-Bridged Donor-Accepter-Donor Fluorescent Probe for Lipid Droplet-Specific Imaging in Diverse Cells and Superoxide Anion Generation	11
Single-dose pharmacokinetics and lung function of nebulized niclosamide ethanolamine in sheep	10
Strategies to Stabilize Dalbavancin in Aqueous Solutions; Section-1: the Effects of Metal Ions and Buffers	10
Trends in Light and Temperature Sensitivity Recommendations among Licensed Biotechnology Drug Products	10
Physiologically Based Biopharmaceutics Model for Selumetinib Food Effect Investigation and Capsule Dissolution Safe Space – Part I: Adults	10
Changes in the Fraction Metabolized in Children Younger than Four Years; When is Clearance Scaling for the Dominant Elimination Route in Adults Appropriate?	10
Olmesartan niosomes ameliorates the Indomethacin-induced gastric ulcer in rats: Insights on MAPK and Nrf2/HO-1 signaling pathway	10
Clinical Investigation of Large Volume Subcutaneous Delivery up to 25 mL for Lean and Non-Lean Subjects	10
Intradermal Vaccination with PLGA Nanoparticles via Dissolving Microneedles and Classical Injection Needles	10
Sialic Acid-based Glycoconjugation on Myricetin-encapsulated Cationic Nanocarriers for the Treatment of Alzheimer's	10
Microneedle Mediated Iontophoretic Delivery of Tofacitinib Citrate	10
Challenges and Opportunities for Celecoxib Repurposing	10
Shedding Light on the Blood–Brain Barrier Transport with Two-Photon Microscopy In Vivo	10
Correction: Leveraging Model Master Files for Long-Acting Injectables	10
In Vitro ADME and Preclinical Pharmacokinetics of Ulotaront, a TAAR1/5-HT1A Receptor Agonist for the Treatment of Schizophrenia	10
Physiologically Based Pharmacokinetic Model of Brain Delivery of Plasma Protein Bound Drugs	10
High Content Image Analysis of Cellular Responses of the Murine J774A.1 Cell Line and Primary Human Cells Alveolar Macrophages to an Extended Panel of Pharmaceutical Agents	10
Effects of Intradermal Administration Volume Using a Hollow Microneedle on the Pharmacokinetics of Fluorescein Isothiocyanate Dextran (M.W. 4,000)	10
Mathematical and Pharmacokinetic Approaches for the Design of New 3D Printing Inks Using Ricobendazole	10
Finite Element Modeling of Powder Compaction: Mini-Tablets in Comparison with Conventionally Sized Tablets	9
Chemical Distribution Uniformity Assessment of “Intra-Tablet” by Hyperspectral Raman Imaging Analysis	9
Revisiting the Effect of Aging on the Transport of Molecules through the Skin	9
Predicting Drug-Drug Interactions Involving Rifampicin Using a Semi-mechanistic Hepatic Compartmental Model	9
Identification of Four Similar Cell Culture Media According to their Glucose, Glutamine, and Pyruvate Content by Handheld Raman Spectroscopy	9
Modeling Dual Drug Delivery from Eluting Stents: The Influence of Non-Linear Binding Competition and Non-Uniform Drug Loading	9
Assessment of Escherichia coli-derived Recombinant Human Bone Morphogenic Protein-2 on Fertilization and Early Embryonic Development in Rats	9
Comparative Thermodynamics of the Reversible Self-Association of Therapeutic mAbs Reveal Opposing Roles for Linked Proton- and Ion-Binding Events	9
Assessment of High-Power Electronic Nicotine Delivery System as an Alternative Aerosol Device for Terbutaline Delivery	9
Mechanisms of Crystal Plasticization by Lattice Water	9
Evaluation of the Combination of L‑leucine to Chitosan on Sustained Release of Inhalable Heparin Sodium Microparticles	9
Pharmacological Innovations in Space: Challenges and Future Perspectives	9
Pre-clinical Formulation Development of an in situ Meglumine Salt of AZD5991: A Novel Macrocyclic Mcl-1 Inhibitor	9
Can Extracellular Vesicles as Drug Delivery Systems Be a Game Changer in Cardiac Disease?	9
The Impact of Drug Properties and Severity of Obesity on Renal Drug Clearance Through Glomerular Filtration and Active Tubular Secretion: A Systematic Analysis Using PBPK Modeling	9
In-Vivo Tape Stripping Study with Caffeine for Comparisons on Body Sites, Age and Washing	9
Vehicles for Drug Administration to Children: Results and Learnings from an In-Depth Screening of FDA-Recommended Liquids and Soft Foods for Product Quality Assessment	9
Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy	9
The Extension of the LeiCNS-PK3.0 Model in Combination with the “Handshake” Approach to Understand Brain Tumor Pathophysiology	8
Computational Modelling of the Impact of Evaporation on In-Vitro Dermal Absorption	8
Embracing Project Optimus: Can we Leverage Evolutionary Theory to Optimize Dosing in Oncology?	8
Hollow MnO2-Based Nanoprobes for Enhanced Photothermal/Photodynamic /Chemodynamic Co-Therapy of Hepatocellular Carcinoma	8
Optimisation of Pharmaceutical Cocrystal Dissolution Performance through a Synergistic Precipitation Inhibition	8
Susceptibility of Lung Carcinoma Cells to Nanostructured Lipid Carrier of ARV-825, a BRD4 Degrading Proteolysis Targeting Chimera	8
DeepSeek-LLM with Adaptive RAG for Pharmaceutical Dissolution Prediction	8
Characterization of Aripiprazole Uptake Transporter in the Blood-Brain Barrier Model hCMEC/D3 Cells by Targeted siRNA Screening	8
Assessing Impact of Food on Oral Drug Bioequivalence Supporting ICH M13 A with the Advancements of Physiologically Based Pharmacokinetic Modeling	8
Thermodynamics and In-Plane Viscoelasticity of Anionic Phospholipid Membranes Modulated by an Ionic Liquid	8
Fcγ Receptor-Dependent Internalization and Off-Target Cytotoxicity of Antibody-Drug Conjugate Aggregates	8
Feasibility Studies of Nebulized SARS-CoV-2 Neutralizing Antibody in Mice and Cynomolgus Monkeys	8
Translational Modeling Identifies Synergy between Nanoparticle-Delivered miRNA-22 and Standard-of-Care Drugs in Triple-Negative Breast Cancer	8
In-Silico Modelling of Transdermal Delivery of Macromolecule Drugs Assisted by a Skin Stretching Hypobaric Device	8
Characterization of mRNA Lipid Nanoparticles by Electron Density Mapping Reconstruction: X-ray Scattering with Density from Solution Scattering (DENSS) Algorithm	8
A Reference Standard for Analytical Testing of Erythropoietin	8
Protein Based Amorphous Solid Dispersion: a Case Study Investigating Different Whey Proteins at High Drug Loading	8
Berberine Improves the Protective Effects of Metformin on Diabetic Nephropathy in db/db Mice through Trib1-dependent Inhibiting Inflammation	8
Quantum Cascade Laser Based Infrared Spectroscopy: A New Paradigm for Protein Secondary Structure Measurement	8
Nicotinamide Mononucleotide and Nicotinamide Riboside Reverse Ovarian Aging in Rats Via Rebalancing Mitochondrial Fission and Fusion Mechanisms	8
Biophysical, Molecular and Proteomic Profiling of Human Retinal Organoid-Derived Exosomes	8
In vitro Dissolution Testing of Rifampicin Powder Formulations For Prediction of Plasma Concentration–Time Profiles After Inhaled Delivery	8
Inhaled Indomethacin-Loaded Liposomes as Potential Therapeutics against Non-Small Cell Lung Cancer (NSCLC)	8
Lipid Microparticles Show Similar Efficacy With Lipid Nanoparticles in Delivering mRNA and Preventing Cancer	8
Applications of Model-Based Meta-Analysis in Drug Development	8
Effect of “In Use” Administration on Topical Product Metamorphosis and Skin Permeation of Acyclovir Creams: Implications for Bioequivalence	8
IVIVC Revised	8
Role of Charge Heterogeneity on Physical Stability of Monoclonal Antibody Biotherapeutic Products	7
The Effects of Solid Particle Containing Inks on the Printing Quality of Porous Pharmaceutical Structures Fabricated by 3D Semi-Solid Extrusion Printing	7
Antimicrobial Activity Classification of Imidazolium Derivatives Predicted by Artificial Neural Networks	7
Activation of Inflammation by MCF-7 Cells-Derived Small Extracellular Vesicles (sEV): Comparison of Three Different Isolation Methods of sEV	7
Drug complexes: Perspective from Academic Research and Pharmaceutical Market	7