Pharmaceutical Research

Article	Citations
Combating Alcohol Adduct Impurity in Immunosuppressant Drug Product Manufacturing: A Scientific Investigation for Enhanced Process Control	204
Modeling Gasotransmitter Availability to Brain Capillary Endothelial Cells with Ultrasound-sensitive Microbubbles	152
A Comprehensive Design-to-skin Pipeline to Fabricate Polymeric Microneedles Using Ultrahigh-resolution 3D Printing	124
Analytical Workflows to Unlock Predictive Power in Biotherapeutic Developability	102
Cationic Ester Prodrugs of Curcumin with N,N-dimethyl Amino Acid Promoieties Improved Poor Water Solubility and Intestinal Absorption	75
Pharmacokinetic Assessment of Drug Efflux from Erythrocytes Loaded with Corticosteroid Esters	64
In Vitro and In Silico Investigations on Drug Delivery in the Mouth-Throat Models with Handihaler®	60
Drug Release from Surfactant-Containing Amorphous Solid Dispersions: Mechanism and Role of Surfactant in Release Enhancement	59
Unambiguous Identification of Glucose-Induced Glycation in mAbs and other Proteins by NMR Spectroscopy	56
Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice	52
Relative Performance of Volume of Distribution Prediction Methods for Lipophilic Drugs with Uncertainty in LogP Value	49
Development of Amorphous Solid Dispersion Sustained-Release Formulations with Polymer Composite Matrix-Regulated Stable Release Plateaus	49
Brain Targeted Curcumin Loaded Turmeric Oil Microemulsion Protects Against Trimethyltin Induced Neurodegeneration in Adult Zebrafish: A Pharmacokinetic and Pharmacodynamic Insight	47
Thermo-Responsive Polymer-siRNA Conjugates Enabling Artificial Control of Gene Silencing around Body Temperature	46
Discovery and Control of Succinimide Formation and Accumulation at Aspartic Acid Residues in The Complementarity-Determining Region of a Therapeutic Monoclonal Antibody	46
Perspectives on the Wetting of Solids in Pharmaceutical Systems	46
Computational and Experimental Screening Approaches to Aripiprazole Salt Crystallization	46
Professor Margareta Hammarlund-Udenaes – a Modern and Visionary Mentor	45
Utilizing Octanoic Acid to Quantitatively Assess the Oxidation Status of PS80	44
Photo-Oxidation Mechanisms in Liquid Pharmaceutical Formulations: The Overlooked Role of Singlet Oxygen Presented as a Case Study	43
Revolutionizing Heart Failure Therapy: Harnessing IVT mRNA and Fusion Protein Technology to Prolong rhBNP Half-Life	43
PEGylation of Propofol Reduces Its Adsorption to Extracorporeal Membrane Oxygenator (ECMO) Components	42
Coupling Drug Dissolution with BCS	42
Correction: A Preformulation Experiment: The Influence of Poloxamer 188 and Poloxamer 407 on the Binding Coefficients (Single Molecule) and the Partitioning Coefficients (Micelle) of Ketoprofen (Probe	41
Controlling Gastric Delivery of a GIP/GLP1 Peptide in Monkeys by Mucoadhesive SNAC Tablets	41

Therapeutic Potential of Semaglutide, a Newer GLP-1 Receptor Agonist, in Abating Obesity, Non-Alcoholic Steatohepatitis and Neurodegenerative diseases: A Narrative Review	40
Advancements in Particle Engineering for Inhalation Delivery of Small Molecules and Biotherapeutics	39
Learning Chemotherapy Drug Action via Universal Physics-Informed Neural Networks	38
Cortisol as Biomarker for CYP17-Inhibition is Associated with Therapy Outcome of Abiraterone Acetate	38
Modulation of Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway in Gastrointestinal Cancers by Phytochemicals	37
Delivery of Corn-Derived Nanoparticles with Anticancer Activity to Tumor Tissues by Modification with Polyethylene Glycol for Cancer Therapy	36
Enhanced Penetration and Retention of an Antibody in the Articular Cartilage Through Aggrecan Binding and Molecular Downsizing	36
Physiologically-Based Pharmacokinetic Modeling of PAXLOVID™ with First-Order Absorption Kinetics	35
Design of an Ante-enhancer with an Azone-Mimic Structure using Ionic Liquid	35
QbD Optimized Nanoemulsion Based Topical Formulation of Jatyadi Taila: Unveiling its In Vitro and In Vivo Efficacy for Enhanced Wound Healing	33
Investigation of an Uncommon Artifact during Reducing Capillary Electrophoresis-Sodium Dodecyl Sulfate Analysis of a Monoclonal Antibody with Dynamic Light Scattering and Reversed Phase High-Performan	33
Peptide Acylation in Aliphatic Polyesters: a Review of Mechanisms and Inhibition Strategies	32
Phase Transitions Involving Channel Hydrates of a New Pharmaceutical Compound	32
Oral Delivery of Nucleic Acid Therapies for Local and Systemic Action	32
Microdialysis of Drug and Drug Metabolite: a Comprehensive In Vitro Analysis for Voriconazole and Voriconazole N-oxide	31
Model-Guided Development of a Semi-Continuous Drying Process	30
Temperature and Heat Transfer Control During Freeze Drying. Effect of Vial Holders and Influence of Pressure	30
Generic Enrichment Method for Liquid Chromatography-Multiple Reaction Monitoring-Mass Spectrometry Assay for Quantitative Measurement of Biological Therapeutics in Serum	30
Design Considerations for Intratracheal Delivery Devices to Achieve Proof-of-Concept Dry Powder Biopharmaceutical Delivery in Mice	29
A Tale of Two Stressors in Biologic Drug Product Development: Shaking Mode and Primary Packaging	29
Improved Pharmaceutical Properties of Honokiol via Salification with Meglumine: an Exception to Oft-quoted ∆pKa Rule	28
Optimization of Vancomycin Initial Dose in Term and Preterm Neonates by Machine Learning	28
Novel Pharmaceutical Cocrystals of Tegafur: Synthesis, Performance, and Theoretical Studies	28
Efficacy of Inhalable Endolysin Cpl-1 Formulations in Combination with Gentamicin or Endolysin Pal in a Murine Lung Infection Model	27
A Novel Non-Aqueous Emulsification Platform to Fabricate Polymeric Microspheres for Sustained Delivery of Biologics	27
Editorial Expression of Concern: Regulation of miR-19 to Breast Cancer Chemoresistance Through Targeting PTEN	26
Topical Semisolid Drug Product Critical Quality Attributes with Relevance to Cutaneous Bioavailability and Pharmacokinetics: Part I—Bioequivalence of Acyclovir Topical Creams	26
A Novel Combination Therapy of Erythropoietin and Thrombopoietin to Treat Erythropoietin-Resistance anemia	25
Modification of Peptide and Permeation Enhancer In Vitro Release Rates by Dispersion with a Gel-Forming Polymer	25
N-terminus of Etanercept is Proteolytically Processed by Dipeptidyl Peptidase-4	24
The Osmolality and Hemolysis of High-Concentration Monoclonal Antibody Formulations	24
Progress in the Application of Microneedles in Eye Disorders and the Proposal of the Upgraded Microneedle with Spinule	23
Hydration Mechanism and Its Effect on the Solubility of Aripiprazole	23
Development and Evaluation of Dual Microneedle Array Patch for Sequential Intradermal Delivery of Adjuvant and Antigen	23
Elucidating the Impact of Material Properties on Tablet Manufacturability for Binary Paracetamol Blends	23
Formulation and Validation of an Extended Sigmoid Emax Model in Pharmacodynamics	23
Natural Powerhouse Duo: Hierarchical Levan Hydrogels with Nanoencapsulated Cannabidiol as Local Delivery Systems	22
Decrease in In Vivo Efflux Transport via P-glycoprotein at the Rat Inner Blood-Retinal Barrier by Peripheral Administration of Lipopolysaccharide	22
Retraction Note: Characterization of Preclinical Pharmacokinetic Properties and Prediction of Human PK Using a Physiologically Based Pharmacokinetic Model for a Novel Anti-Arrhythmic Agent Sulcardine	21
Amyloid Light Chain Proteins in Cardiovascular Disease: Pathogenesis and Emerging Therapies for Cardiac Amyloidosis	21
Application of Twin-Screw Melt Granulation to Overcome the Poor Tabletability of a High Dose Drug	21
In vitro and ex vivo Pharmacological Profile of HY-022619, a Novel Intravenous P2Y12 Receptor Antagonist with Rapid-onset and Sustained Antiplatelet Activity	20
Sensitivity and Uncertainty Analysis of Micro-Flow Imaging for Sub-Visible Particle Measurements Using Artificial Neural Network	20
REAL208, a Liposome-based Formulation of Phosphodiesterase Inhibitor, Protects Acute Kidney Deficiency in Mice	20
Nanobody-Oligonucleotide Conjugates (NucleoBodies): The Next Frontier in Oligonucleotide Therapy	20
N-oxidation Regioselectivity and Risk Prediction Using DFT-ALIE Calculations	18
Correction to: Liposomal Formulation for Oral Delivery of Cyclosporine A: Usefulness as a Semisolid-Dispersion System	18
Dissolution Profiles of Poorly Soluble Drug Salts in Bicarbonate Buffer	18
Efficient Cytosolic Delivery of siRNA Using Lyophilized and Reconstituted Polymer-siRNA Polyplexes	18
Local Delivery of Non-opioid Analgesic Microparticles to Modulate Post-surgical Pain	18

Predictive Value of Vancomycin AUC24/MIC Ratio for 30-day Mortality in Patients with Severe or Complicated Methicillin-Resistant Staphylococcus aureus Infections: A Multicenter Retrospective Study	18
Time-Lapse Macro Imaging with Dissolution Tests for Exploring the Interrelationship Between Disintegration and Dissolution Behaviors of Solid Dosages	18
Impostor Phenomenon and Grit as Predictors of Job Satisfaction in Female Pharmacy Faculty	18
Application of PAT Probes in Aluminum Phosphate Adjuvant Manufacturing	18
Assessment of Minipigs as a Non-clinical Model for Screening and Derisking Injection Site Reactions in Clinical Trials	17
Role of ITIH4 in Modulating YAP/TAZ-Mediated Apoptosis of Type II Alveolar Epithelium during Acute Respiratory Distress Syndrome	17
From Blood Flow to Tumor Cell Internalization: A Multistage Computational Model of Nanoparticle Dynamics	17
Accelerating Process Development and Product Formulation	17
A Model-Based Evaluation of Noninvasive Biomarkers to Reflect Histological Nonalcoholic Fatty Liver Disease Scores	17
Understanding the Phagocytosis of Particles: the Key for Rational Design of Vaccines and Therapeutics	17
Numerical Investigation to Improve Pulmonary Drug Delivery via Dry Powder Inhalers: A Review of In-Silico Modeling	17
Acetylcholine Analog-Modified Albumin Nanoparticles for the Enhanced and Synchronous Brain Delivery of Saponin Components of Panax Notoginseng	17
An Evaluation of Wet Granulation Process Selection for API Prone to Polymorphic Form Conversion in the Presence of Moisture and Heat	16
Optimization of Lung Surfactant Coating of siRNA Polyplexes for Pulmonary Delivery	16
Coformer-Dependent Physical Stability in a Series of Naringenin-Based Coamorphous Materials with Caffeine, Theophylline, and Theobromine	16
In Vitro-In Vivo Correlation Of Amorphous Solid Dispersion Enabled Itraconazole Tablets	16
Convolutional Neural Networks Guided Raman Spectroscopy as a Process Analytical Technology (PAT) Tool for Monitoring and Simultaneous Prediction of Monoclonal Antibody Charge Variants	16
Fluorinated PAMAM-Arginine Carrier Prodrugs for pH-Sensitive Sustained Ibuprofen Delivery	16
Differences in Pharmacokinetic/Pharmacodynamic Parameters of Tedizolid Against VRE and MRSA	16
Development of a New Dry Powder Aerosol Synthetic Lung Surfactant Product for Neonatal Respiratory Distress Syndrome (RDS) – Part II: In vivo Efficacy Testing in a Rabbit Surfactant Washout Model	16
Microneedle-Mediated Permeation Enhancement of Chlorhexidine Digluconate: Mechanistic Insights Through Imaging Mass Spectrometry	16
Pharmacokinetic Profile of Brepocitinib with Topical Administration in Atopic Dermatitis and Psoriasis Populations: Strategy to Inform Clinical Trial Design in Adult and Pediatric Populations	15
Polymorphism of Pradofloxacin: Crystal Structure Analysis, Stability Study, and Phase Transformation Behavior	15
Enhancing the Stability, Solubility, and Antioxidant Activity of Cinchonine through Pharmaceutical Cocrystallization	15
Ionic Liquids: Emerging Antimicrobial Agents	15
Tabletability Flip in Dry Granulated Systems	14
Co-delivery of Brinzolamide and Timolol from Micelles-laden Contact Lenses: In vitro and In Vivo Evaluation	14
Applications of Model Informed Drug Development (MIDD) in Drug Development Lifecycle and Regulatory Review	14
‘Whole-Body Pharmacokinetics of Lipid, mRNA and Translated Protein Following Intravenous Administration of Spike Protein Expressing mRNA-LNP in Mice’	14
Aerosolizable Plasmid DNA Dry Powders Engineered by Thin-film Freezing	14
A Hollow Microneedle Equipped with a Micropillar for Improved Needle Insertion and Injection of Drug Solution	14
Development of an Accelerated Rotator-based Drug Release Method for the Evaluation of Bupivacaine Multivesicular Liposomes	14
Evaluation of Encequidar as An Intestinal P-gp and BCRP Specific Inhibitor to Assess the Role of Intestinal P-gp and BCRP in Drug-Drug Interactions	14
Improvement of Workflows and Assay Reproducibility by The Introduction of “Assay-Ready” Culturing of MDCK Cells for Transport Studies	14
Roles and Application of Extracellular Vesicles Occurring Endogenously and Naturally	14
miRNA Signature of Urine Extracellular Vesicles Shows the Involvement of Inflammatory and Apoptotic Processes in Diabetic Chronic Kidney Disease	14
The Advanced Integrated Respiratory (AIR) Model: Comparative Analysis of Salbutamol Sulphate Deposition from pMDI, DPI, and Nebuliser Versus the NGI	13
Adopting the Model Master File Framework to Enhance Modeling and Simulations Approaches for Regulatory Use	13
Preclinical Toxicity Study and Tissue Distribution of YSCH- 01 Injection via Intratumoral Injection, Intravenous Injection, and Intraperitoneal Injection in Syrian Hamsters	13
Development of a Novel Curcumin-Vanillic Acid Eutectic: Physicochemical Characterization, Antioxidant Activity, and Bioavailability Enhancement	13
Physiologically Based Pharmacokinetic Modeling for Prediction of 5-FU Pharmacokinetics in Cancer Patients with Hepatic Impairment After 5-FU and Capecitabine Administration	13
Evaluation of Pharmacokinetic and Pharmacodynamic (PK/PD) of Novel Fluorenylmethoxycarbonyl- Phenylalanine Antimicrobial Agent	13
Leveraging Model Master Files from a Technology Company Perspective: Facilitating Quantitative Medicine in Regulatory Frameworks	13
The Impact of Particle Properties on High Concentration Suspension Performance and Stability of Spray-Dried Monoclonal Antibodies	13
Characteristics of Tylvalosin Tartrate Enteric Amorphous Pellets Prepared by Liquid Layering	13
An Overview of Endometriosis and Potential Pharmacogenetic Targets	13
Mechanistic Modelling of Transdermal Delivery Dependence on Drug Properties	12
A New Analytical LC–MS/MS Method for Determination of Eight Standard Nitrosamines (NDMA, NMBA, NDEA, NEIPA, NDIPA, NMPA, NDPA, NDBA) in a Commercial Small Molecule Drug Product Capsules and its Active	12
Use of Flory–Huggins Interaction Parameter and Contact Angle Values to Predict the Suitability of the Drug-Polymer System for the Production and Stability of Nanosuspensions	12
Research Landscape of Physiologically Based Pharmacokinetic Model Utilization in Different Fields: A Bibliometric Analysis (1999–2023)	12
Reference Standards to Support Quality of Synthetic Peptide Therapeutics	12
Development of Candesartan Cilexetil-sodium Carbonate Anhydrate-mesoporous Silica Solid Dispersion in Polymer-free System	12
Modeling Multiphase Heat and Mass Transfer in an Agitated Filter Dryer by Integrating Experiment, Computations, and Analytical Solutions	12
Discovery of the Next Generation of Non-peptidomimetic Neurolysin Activators with High Blood-Brain Barrier Permeability: a Pharmacokinetics Study in Healthy and Stroke Animals	12
Validation of Anti-Adeno Associated Virus Serotype rh10 (AAVrh.10) Total and Neutralizing Antibody Immunogenicity Assays	12
Retraction Note: Combination Cancer Immunotherapy with Dendritic Cell Vaccine and Nanoparticles Loaded with Interleukin-15 and Anti-beta-catenin siRNA Significantly Inhibits Cancer Growth and Induces	12
The Impact of Post-Processing Temperature on PLGA Microparticle Properties	12
Continuous Electrospraying of Inhalable Biological Drug Products: Novel Formulation and Manufacturing Technology	12
Incorporating Uremic Solute-mediated Inhibition of OAT1/3 Improves PBPK Prediction of Tenofovir Renal and Systemic Disposition in Patients with Severe Kidney Disease	12
Influence of Milling Parameters on Crystal Morphology, Thermal Behavior, and Dissolution of Mesalamine Nanocrystals	12
An Enthalpy-Balance Model for Timewise Evolution of Temperature during Wet Stirred Media Milling of Drug Suspensions	12
Direct Assessment of Oligomerization of Chemically Modified Peptides and Proteins in Formulations using DLS and DOSY-NMR	12
Mechanism of Insoluble Aggregate Formation in a Reconstituted Solution of Spray-Dried Protein Powder	12
Structure and Function of Cationic and Ionizable Lipids for Nucleic Acid Delivery	11
Critical Needs and Opportunities for Advanced Manufacturing of Lyophilized Injectables	11
Inhalable N-Acetylcysteine-loaded Lactose-coated PLGA Nanoparticles for Tuberculosis Treatment	11
Effect of Buffer Salts on Physical Stability of Lyophilized and Spray-Dried Protein Formulations Containing Bovine Serum Albumin and Trehalose	11
Rapid Development of High Concentration Protein Formulation Driven by High-Throughput Technologies	11
Solubility vs Dissolution in Physiological Bicarbonate Buffer	11
Recent Progress in Exosome-Derived Nanocarriers for Breast Cancer Therapy: Advances, Translational Barriers, and Scale-Up Considerations	11
Strategies to improve the physicochemical properties of peptide-based drugs	11
Evaluation of In Vitro Metabolism- and Transporter-Based Drug Interactions with Sunscreen Active Ingredients	11
Impact of Pre-Actuation Shaking on the Aerosolization Performance of Easyhaler® Salbutamol Dry Powder Inhaler	11
Raman Spectroscopic Analysis of Highly-Concentrated Antibodies under the Acid-Treated Conditions	11
Correction: Practical Advice on Scientific Design of Freeze-Drying Process: 2023 Update	11
Polymorphism Control of Carbamazepine Based on Deep Eutectic Solvents	11
Enhanced Solubilization of Ketoprofen Using Triton X-100, Triton X-165, Brij C10, and Their Binary and Ternary Mixed Micelle Systems	11
Preclinical Evaluation of AAV8-R338L Gene Therapy for Hemophilia: Efficacy, Pharmacokinetics, Distribution, Excretion and Toxicity in Mouse Models and Non-human Primates	11
The Role of Artificial Intelligence and Machine Learning in Accelerating the Discovery and Development of Nanomedicine	11
Impact of Select Geometric and Operational Parameters on Hydrodynamics in Dissolution Apparatus 2 (Paddle Apparatus): A Design of Experiments Analysis Based on Computational Fluid Dynamics Simulations	11

Directing the Way—Receptor and Chemical Targeting Strategies for Nucleic Acid Delivery	11
Dissolution Profiles Comparison Using Various Model Independent Statistical Approaches: Can We Increase Chance of Similarity?	11
Design, Development, and Characterization of a Tannic Acid-loaded Transfersomal Gel for Psoriatic Skin	11
Bionanoconjugates in Neurodegeneration: Peptide–Nanoparticle Alliances for Next-Generation Therapies	11
Dextran Mass Ratio Controls Particle Drying Dynamics in a Thermally Stable Dry Powder Vaccine for Pulmonary Delivery	11
In vivo Pharmacokinetic/Pharmacodynamic Analysis of the Efficacy of the Cefepime/Nacubactam Combination Against β-Lactamase-Producing Enterobacterales based on the Instantaneous MIC Concept	10
The Acute Impact of Propofol on Blood–Brain Barrier Integrity in Mice	10
Single-dose pharmacokinetics and lung function of nebulized niclosamide ethanolamine in sheep	10
Changes in the Fraction Metabolized in Children Younger than Four Years; When is Clearance Scaling for the Dominant Elimination Route in Adults Appropriate?	10
Correction: Leveraging Model Master Files for Long-Acting Injectables	10
Novel Self-Assembled Micelles With Increased Tumor Penetration and Anti-Tumor Efficiency Against Breast Cancer	10
Melt-Extruded Paclitaxel Nanocrystal-Loaded Sutures for Sustained Local Drug Delivery	10
Strategies to Stabilize Dalbavancin in Aqueous Solutions; Section-1: the Effects of Metal Ions and Buffers	10
Intradermal Vaccination with PLGA Nanoparticles via Dissolving Microneedles and Classical Injection Needles	10
Physiologically Based Pharmacokinetic Model of Brain Delivery of Plasma Protein Bound Drugs	10
Effect of Structurally Related Compounds on Desupersaturation Kinetics of Indomethacin	10
Nanotherapeutics to Overcome Chemotherapy Resistance in Ovarian Cancer	10
Freezing-Induced Stress in mRNA-Lipid Nanoparticles During Lyophilization: Mechanistic Insights From Process and Formulation Studies	10
Effects of Intradermal Administration Volume Using a Hollow Microneedle on the Pharmacokinetics of Fluorescein Isothiocyanate Dextran (M.W. 4,000)	10
Correction: Effect of Buffer Salts on Physical Stability of Lyophilized and Spray-Dried Protein Formulations Containing Bovine Serum Albumin and Trehalose	10
Mathematical and Pharmacokinetic Approaches for the Design of New 3D Printing Inks Using Ricobendazole	10
In-Silico Modelling of Transdermal Delivery of Macromolecule Drugs Assisted by a Skin Stretching Hypobaric Device	9
Evaluation of the Combination of L‑leucine to Chitosan on Sustained Release of Inhalable Heparin Sodium Microparticles	9
Hollow MnO2-Based Nanoprobes for Enhanced Photothermal/Photodynamic /Chemodynamic Co-Therapy of Hepatocellular Carcinoma	9
Challenges and Opportunities for Celecoxib Repurposing	9
Trends in Light and Temperature Sensitivity Recommendations among Licensed Biotechnology Drug Products	9
Physiologically Based Biopharmaceutics Model for Selumetinib Food Effect Investigation and Capsule Dissolution Safe Space – Part I: Adults	9
Clinical Investigation of Large Volume Subcutaneous Delivery up to 25 mL for Lean and Non-Lean Subjects	9
Pre-clinical Formulation Development of an in situ Meglumine Salt of AZD5991: A Novel Macrocyclic Mcl-1 Inhibitor	9
Comparative Thermodynamics of the Reversible Self-Association of Therapeutic mAbs Reveal Opposing Roles for Linked Proton- and Ion-Binding Events	9
Lipid Microparticles Show Similar Efficacy With Lipid Nanoparticles in Delivering mRNA and Preventing Cancer	9
A General Strategy to Compare Stability Slopes of Biologics Using Short-Term data from Post-Change Batches Versus Long-Term Data from Pre-Change Batches	9
Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy	9
Assessment of Escherichia coli-derived Recombinant Human Bone Morphogenic Protein-2 on Fertilization and Early Embryonic Development in Rats	9
Translation from Preclinical Research to Clinical Trials: Transdermal Drug Delivery for Neurodegenerative and Mental Disorders	9
High Content Image Analysis of Cellular Responses of the Murine J774A.1 Cell Line and Primary Human Cells Alveolar Macrophages to an Extended Panel of Pharmaceutical Agents	9
Regional Nasal Drug Deposition in Pediatric vs. Adult Models: In vitro Insights into User Technique and Breathing Patterns Sensitivity	9
Enabling Efficient Design of Biological Formulations through Advanced Characterizations	9
Chemical Distribution Uniformity Assessment of “Intra-Tablet” by Hyperspectral Raman Imaging Analysis	9
Pharmacological Innovations in Space: Challenges and Future Perspectives	9
Effect of “In Use” Administration on Topical Product Metamorphosis and Skin Permeation of Acyclovir Creams: Implications for Bioequivalence	9
Identification of Four Similar Cell Culture Media According to their Glucose, Glutamine, and Pyruvate Content by Handheld Raman Spectroscopy	9
Finite Element Modeling of Powder Compaction: Mini-Tablets in Comparison with Conventionally Sized Tablets	9
Can Extracellular Vesicles as Drug Delivery Systems Be a Game Changer in Cardiac Disease?	9
Biopharmaceutic Assessment of Post-Approval Changes for Azithromycin Immediate Release Tablets Using Predictive In Vitro Dissolution and a Model-Informed Approach	9
Shedding Light on the Blood–Brain Barrier Transport with Two-Photon Microscopy In Vivo	9
Sialic Acid-based Glycoconjugation on Myricetin-encapsulated Cationic Nanocarriers for the Treatment of Alzheimer's	9
Pharmacokinetic Modeling of the Effect of Tariquidar on Ondansetron Disposition into the Central Nervous System	9
Predicting Drug-Drug Interactions Involving Rifampicin Using a Semi-mechanistic Hepatic Compartmental Model	9
Revisiting the Effect of Aging on the Transport of Molecules through the Skin	9
Embracing Project Optimus: Can we Leverage Evolutionary Theory to Optimize Dosing in Oncology?	8
Assessing Impact of Food on Oral Drug Bioequivalence Supporting ICH M13 A with the Advancements of Physiologically Based Pharmacokinetic Modeling	8
Advanced in Co-Delivery, Controllable Therapy using Microneedle: From Design to Therapeutic Effects	8
Protein Based Amorphous Solid Dispersion: a Case Study Investigating Different Whey Proteins at High Drug Loading	8
Characterization of mRNA Lipid Nanoparticles by Electron Density Mapping Reconstruction: X-ray Scattering with Density from Solution Scattering (DENSS) Algorithm	8
Optimisation of Pharmaceutical Cocrystal Dissolution Performance through a Synergistic Precipitation Inhibition	8
Inhaled Indomethacin-Loaded Liposomes as Potential Therapeutics against Non-Small Cell Lung Cancer (NSCLC)	8
Lipid Nanoparticle Development in Practice: Challenges and Collective Insights	8
Feasibility Studies of Nebulized SARS-CoV-2 Neutralizing Antibody in Mice and Cynomolgus Monkeys	8
Biophysical, Molecular and Proteomic Profiling of Human Retinal Organoid-Derived Exosomes	8
Computational Modelling of the Impact of Evaporation on In-Vitro Dermal Absorption	8
The Advanced Integrated Respiratory (AIR) Model: Integration of Air–Liquid Interface Cell Cultures within a Human Airway Model for Inhalation Toxicology	8
In-Vivo Tape Stripping Study with Caffeine for Comparisons on Body Sites, Age and Washing	8
Modeling Dual Drug Delivery from Eluting Stents: The Influence of Non-Linear Binding Competition and Non-Uniform Drug Loading	8
Novel 3D Printed Modular Tablets Containing Multiple Anti-Viral Drugs: a Case of High Precision Drop-on-Demand Drug Deposition	8
Preparation and Characterization of Novel Pan-RAS Inhibitor Loaded Ultraflexible Liposomes for the Topical Prevention or Treatment of Skin Melanoma	8
Evaluation of Mannitol's Crystallization Impact on the Secondary Structure of Spray-Dried recombinant human Growth Hormone (rhGH) Formulations	8
Quantum Cascade Laser Based Infrared Spectroscopy: A New Paradigm for Protein Secondary Structure Measurement	8
The Impact of Drug Properties and Severity of Obesity on Renal Drug Clearance Through Glomerular Filtration and Active Tubular Secretion: A Systematic Analysis Using PBPK Modeling	8
DeepSeek-LLM with Adaptive RAG for Pharmaceutical Dissolution Prediction	8
In vitro Dissolution Testing of Rifampicin Powder Formulations For Prediction of Plasma Concentration–Time Profiles After Inhaled Delivery	8
An In Vitro Dissolution Method for Inhaled Drugs Depositing in the Tracheobronchial Lung Region	7
In Vitro Inhalation and Deposition of Salbutamol in Upper Airway Geometries	7
Multi-Target Anticoagulant Regulation by Peptides from Medicinal Leeches: A Unique Natural Strategy against Thrombosis	7
Regulatory Roles of Long Non-Coding RNAs in Methotrexate Pharmacology: Mechanistic and Translational Insights	7
Fabrication of Polymeric Microneedles using Novel Vacuum Compression Molding Technique for Transdermal Drug Delivery	7
Development and Validation of Discriminatory In-vitro Release Method for Intramammary Drug Product	7
Activation of Inflammation by MCF-7 Cells-Derived Small Extracellular Vesicles (sEV): Comparison of Three Different Isolation Methods of sEV	7
Functional Evaluation of P-gp and Bcrp at the Murine Blood-Cerebrospinal Fluid Barrier	7
Role of Charge Heterogeneity on Physical Stability of Monoclonal Antibody Biotherapeutic Products	7
Assessment of the Effects of Ionizing Radiation on Biologic Drugs: mAb Product Quality and Risk Evaluation for Global Shipping Logistics	7
Development and Validation of an Efficient In vitro Bioassay for Potency Estimation of Recombinant Human Erythropoietin Formulations	7
Transcutaneous Delivery of Dual-Approach Oxaprozin and Apricot Kernel Oil Through a QbD Driven Nanoemulgel: Therapeutic Potential Against Osteoarthritis-Induced Animal Model	7
Physicochemical Differences Observed in Photostability Studies of Lyophilized, Reconstituted, and Diluted Somatropin	7
Preclinical Pharmacokinetics of DM5167, a Novel Selective PARP1 Inhibitor	7
Risk Assessment for a Twin-Screw Granulation Process Using a Supervised Physics-Constrained Auto-encoder and Support Vector Machine Framework	7
Combined Treatment of Metformin and Resveratrol Promotes Myogenesis Through Increased Irisin Release in C2C12 Cells	7
Antimicrobial Activity Classification of Imidazolium Derivatives Predicted by Artificial Neural Networks	7
Effect of Material Properties and Variability of Mannitol on Tablet Formulation Development	7
Effect of mPEG-PLGA on Drug Crystallinity and Release of Long-Acting Injection Microspheres: In Vitro and In Vivo Perspectives	7
Identification of a Multi-Component Formulation for Intestinal Delivery of a GLP-1/Glucagon Co-agonist Peptide	7
TGF-β Signaling Activation Confers Anlotinib Resistance in Gastric Cancer	7
Correction: Development of a New Dry Powder Aerosol Synthetic Lung Surfactant Product for Neonatal Respiratory Distress Syndrome (RDS) – Part I: In Vitro Testing and Characterization	7
Transdermal Drug Delivery Systems: A Comprehensive Review of Mechanisms, Technologies, and Clinical Applications	7
Thermodynamics and In-Plane Viscoelasticity of Anionic Phospholipid Membranes Modulated by an Ionic Liquid	7