Pharmaceutical Research

Papers
(The TQCC of Pharmaceutical Research is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Combating Alcohol Adduct Impurity in Immunosuppressant Drug Product Manufacturing: A Scientific Investigation for Enhanced Process Control166
Thermo-Responsive Polymer-siRNA Conjugates Enabling Artificial Control of Gene Silencing around Body Temperature159
Analytical Workflows to Unlock Predictive Power in Biotherapeutic Developability127
Modeling Gasotransmitter Availability to Brain Capillary Endothelial Cells with Ultrasound-sensitive Microbubbles105
Drug Release from Surfactant-Containing Amorphous Solid Dispersions: Mechanism and Role of Surfactant in Release Enhancement88
Effect of Fatty Acid Composition in Polysorbate 80 on the Stability of Therapeutic Protein Formulations81
Discovery and Control of Succinimide Formation and Accumulation at Aspartic Acid Residues in The Complementarity-Determining Region of a Therapeutic Monoclonal Antibody78
Ritonavir-Boosted Exposure of Kinase Inhibitors: an Open Label, Cross-over Pharmacokinetic Proof-of-Concept Trial with Erlotinib67
Safety and Pharmacokinetics of Intranasally Administered Heparin63
Novel Deep Eutectic Solvent–Hydrogel Systems for Synergistic Transdermal Delivery of Chinese Herb Medicine and Local Treatments for Rheumatoid Arthritis61
Pharmacokinetic Assessment of Drug Efflux from Erythrocytes Loaded with Corticosteroid Esters54
Cationic Ester Prodrugs of Curcumin with N,N-dimethyl Amino Acid Promoieties Improved Poor Water Solubility and Intestinal Absorption51
Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice48
Computational and Experimental Screening Approaches to Aripiprazole Salt Crystallization47
Brain Targeted Curcumin Loaded Turmeric Oil Microemulsion Protects Against Trimethyltin Induced Neurodegeneration in Adult Zebrafish: A Pharmacokinetic and Pharmacodynamic Insight43
Unambiguous Identification of Glucose-Induced Glycation in mAbs and other Proteins by NMR Spectroscopy42
Engineering a Remedy to Modulate and Optimize Biopharmaceutical Properties of Rebamipide by Synthesizing New Cocrystal: In Silico and Experimental Studies42
In Vitro and In Silico Investigations on Drug Delivery in the Mouth-Throat Models with Handihaler®40
Perspectives on the Wetting of Solids in Pharmaceutical Systems40
Relative Performance of Volume of Distribution Prediction Methods for Lipophilic Drugs with Uncertainty in LogP Value39
Development of Amorphous Solid Dispersion Sustained-Release Formulations with Polymer Composite Matrix-Regulated Stable Release Plateaus39
Limited Impact of Murine Placental MDR1 on Fetal Exposure of Certain Drugs Explained by Bypass Transfer Between Adjacent Syncytiotrophoblast Layers38
Professor Margareta Hammarlund-Udenaes – a Modern and Visionary Mentor38
RETRACTED ARTICLE: Characterization of Preclinical Pharmacokinetic Properties and Prediction of Human PK Using a Physiologically Based Pharmacokinetic Model for a Novel Anti-Arrhythmic Agent Sulcardin37
Micafungin Population PK Analysis in Healthy and Septic Pigs: Can the Septic Porcine Model Predict the Micafungin PK in Septic Patients?36
Utilizing Octanoic Acid to Quantitatively Assess the Oxidation Status of PS8036
Cortisol as Biomarker for CYP17-Inhibition is Associated with Therapy Outcome of Abiraterone Acetate35
Revolutionizing Heart Failure Therapy: Harnessing IVT mRNA and Fusion Protein Technology to Prolong rhBNP Half-Life35
Controlling Gastric Delivery of a GIP/GLP1 Peptide in Monkeys by Mucoadhesive SNAC Tablets34
Correction: A Preformulation Experiment: The Influence of Poloxamer 188 and Poloxamer 407 on the Binding Coefficients (Single Molecule) and the Partitioning Coefficients (Micelle) of Ketoprofen (Probe34
PEGylation of Propofol Reduces Its Adsorption to Extracorporeal Membrane Oxygenator (ECMO) Components34
Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells33
Role of Disease Progression Models in Drug Development33
Photo-Oxidation Mechanisms in Liquid Pharmaceutical Formulations: The Overlooked Role of Singlet Oxygen Presented as a Case Study33
Learning Chemotherapy Drug Action via Universal Physics-Informed Neural Networks33
Delivery of Corn-Derived Nanoparticles with Anticancer Activity to Tumor Tissues by Modification with Polyethylene Glycol for Cancer Therapy33
Advancements in Particle Engineering for Inhalation Delivery of Small Molecules and Biotherapeutics33
Therapeutic Potential of Semaglutide, a Newer GLP-1 Receptor Agonist, in Abating Obesity, Non-Alcoholic Steatohepatitis and Neurodegenerative diseases: A Narrative Review33
Coupling Drug Dissolution with BCS33
Enhanced Penetration and Retention of an Antibody in the Articular Cartilage Through Aggrecan Binding and Molecular Downsizing32
A Novel Combination Therapy of Erythropoietin and Thrombopoietin to Treat Erythropoietin-Resistance anemia31
Editorial Expression of Concern: Regulation of miR-19 to Breast Cancer Chemoresistance Through Targeting PTEN31
Design of an Ante-enhancer with an Azone-Mimic Structure using Ionic Liquid31
PAMAM versus PEI complexation for siRNA delivery: interaction with model lipid membranes and cellular uptake30
Phase Transitions Involving Channel Hydrates of a New Pharmaceutical Compound30
Improved Pharmaceutical Properties of Honokiol via Salification with Meglumine: an Exception to Oft-quoted ∆pKa Rule30
Model-Guided Development of a Semi-Continuous Drying Process30
Peptide Acylation in Aliphatic Polyesters: a Review of Mechanisms and Inhibition Strategies29
Novel Pharmaceutical Cocrystals of Tegafur: Synthesis, Performance, and Theoretical Studies29
Multiphysics Modelling and Simulation of Thrombolysis via Activated Platelet-Targeted Nanomedicine28
Temperature and Heat Transfer Control During Freeze Drying. Effect of Vial Holders and Influence of Pressure28
Generic Enrichment Method for Liquid Chromatography-Multiple Reaction Monitoring-Mass Spectrometry Assay for Quantitative Measurement of Biological Therapeutics in Serum28
Modification of Peptide and Permeation Enhancer In Vitro Release Rates by Dispersion with a Gel-Forming Polymer28
Design Considerations for Intratracheal Delivery Devices to Achieve Proof-of-Concept Dry Powder Biopharmaceutical Delivery in Mice28
Physiologically-Based Pharmacokinetic Modeling of PAXLOVID™ with First-Order Absorption Kinetics27
Investigation of an Uncommon Artifact during Reducing Capillary Electrophoresis-Sodium Dodecyl Sulfate Analysis of a Monoclonal Antibody with Dynamic Light Scattering and Reversed Phase High-Performan27
Oral Delivery of Nucleic Acid Therapies for Local and Systemic Action26
Strategy for Cytoplasmic Delivery Using Inorganic Particles26
Topical Semisolid Drug Product Critical Quality Attributes with Relevance to Cutaneous Bioavailability and Pharmacokinetics: Part I—Bioequivalence of Acyclovir Topical Creams26
Retraction Note: Characterization of Preclinical Pharmacokinetic Properties and Prediction of Human PK Using a Physiologically Based Pharmacokinetic Model for a Novel Anti-Arrhythmic Agent Sulcardine 25
Optimization of Vancomycin Initial Dose in Term and Preterm Neonates by Machine Learning25
N-terminus of Etanercept is Proteolytically Processed by Dipeptidyl Peptidase-425
Elucidating the Impact of Material Properties on Tablet Manufacturability for Binary Paracetamol Blends25
Correction to: Re-examining digoxin bioavailability after half a century: Time for changes in the bioavailability concepts25
Microdialysis of Drug and Drug Metabolite: a Comprehensive In Vitro Analysis for Voriconazole and Voriconazole N-oxide25
Decrease in In Vivo Efflux Transport via P-glycoprotein at the Rat Inner Blood-Retinal Barrier by Peripheral Administration of Lipopolysaccharide24
Formulation and Validation of an Extended Sigmoid Emax Model in Pharmacodynamics24
Evaluation of Blood-CSF Barrier Transport by Quantitative Real Time Fluorescence Microscopy24
Development and Evaluation of Dual Microneedle Array Patch for Sequential Intradermal Delivery of Adjuvant and Antigen23
Dissolution Profiles of Poorly Soluble Drug Salts in Bicarbonate Buffer23
The Osmolality and Hemolysis of High-Concentration Monoclonal Antibody Formulations23
Sensitivity and Uncertainty Analysis of Micro-Flow Imaging for Sub-Visible Particle Measurements Using Artificial Neural Network23
Application of Twin-Screw Melt Granulation to Overcome the Poor Tabletability of a High Dose Drug23
Progress in the Application of Microneedles in Eye Disorders and the Proposal of the Upgraded Microneedle with Spinule23
Hydration Mechanism and Its Effect on the Solubility of Aripiprazole22
Nanobody-Oligonucleotide Conjugates (NucleoBodies): The Next Frontier in Oligonucleotide Therapy22
Predictive Value of Vancomycin AUC24/MIC Ratio for 30-day Mortality in Patients with Severe or Complicated Methicillin-Resistant Staphylococcus aureus Infections: A Multicenter Retrospective Study22
Application of PAT Probes in Aluminum Phosphate Adjuvant Manufacturing22
Development of a Physiologically-Based Pharmacokinetic Model for Whole-Body Disposition of MMAE Containing Antibody-Drug Conjugate in Mice21
Time-Lapse Macro Imaging with Dissolution Tests for Exploring the Interrelationship Between Disintegration and Dissolution Behaviors of Solid Dosages21
Correction to: Liposomal Formulation for Oral Delivery of Cyclosporine A: Usefulness as a Semisolid-Dispersion System21
Coformer-Dependent Physical Stability in a Series of Naringenin-Based Coamorphous Materials with Caffeine, Theophylline, and Theobromine20
Impostor Phenomenon and Grit as Predictors of Job Satisfaction in Female Pharmacy Faculty20
A Model-Based Evaluation of Noninvasive Biomarkers to Reflect Histological Nonalcoholic Fatty Liver Disease Scores20
Local Delivery of Non-opioid Analgesic Microparticles to Modulate Post-surgical Pain20
Convolutional Neural Networks Guided Raman Spectroscopy as a Process Analytical Technology (PAT) Tool for Monitoring and Simultaneous Prediction of Monoclonal Antibody Charge Variants20
An Evaluation of Wet Granulation Process Selection for API Prone to Polymorphic Form Conversion in the Presence of Moisture and Heat20
Efficient Cytosolic Delivery of siRNA Using Lyophilized and Reconstituted Polymer-siRNA Polyplexes19
Assessment of Minipigs as a Non-clinical Model for Screening and Derisking Injection Site Reactions in Clinical Trials19
Differences in Pharmacokinetic/Pharmacodynamic Parameters of Tedizolid Against VRE and MRSA19
Numerical Investigation to Improve Pulmonary Drug Delivery via Dry Powder Inhalers: A Review of In-Silico Modeling19
Optimization of Lung Surfactant Coating of siRNA Polyplexes for Pulmonary Delivery19
Microneedle-Mediated Permeation Enhancement of Chlorhexidine Digluconate: Mechanistic Insights Through Imaging Mass Spectrometry19
Development of a New Dry Powder Aerosol Synthetic Lung Surfactant Product for Neonatal Respiratory Distress Syndrome (RDS) – Part II: In vivo Efficacy Testing in a Rabbit Surfactant Washout Model18
Application of Confocal Raman Microscopy for the Characterization of Topical Semisolid Formulations and their Penetration into Human Skin Ex Vivo18
In Vitro-In Vivo Correlation Of Amorphous Solid Dispersion Enabled Itraconazole Tablets18
Consideration of Fractional Distribution Parameter fd in the Chen and Gross Method for Tissue-to-Plasma Partition Coefficients: Comparison of Several Methods18
Accelerating Process Development and Product Formulation18
N-oxidation Regioselectivity and Risk Prediction Using DFT-ALIE Calculations17
A Semi-Physiological Three-Compartment Model Describes Brain Uptake Clearance and Efflux of Sucrose and Mannitol after IV Injection in Awake Mice17
Understanding the Phagocytosis of Particles: the Key for Rational Design of Vaccines and Therapeutics17
Ionic Liquids: Emerging Antimicrobial Agents17
Acetylcholine Analog-Modified Albumin Nanoparticles for the Enhanced and Synchronous Brain Delivery of Saponin Components of Panax Notoginseng17
Fluorinated PAMAM-Arginine Carrier Prodrugs for pH-Sensitive Sustained Ibuprofen Delivery17
Freeze-Dried Biopharmaceutical Formulations are Surprisingly Less Stable than Liquid Formulations during Dropping16
Adopting the Model Master File Framework to Enhance Modeling and Simulations Approaches for Regulatory Use16
Leveraging Model Master Files from a Technology Company Perspective: Facilitating Quantitative Medicine in Regulatory Frameworks16
Applications of Model Informed Drug Development (MIDD) in Drug Development Lifecycle and Regulatory Review16
Polymorphism of Pradofloxacin: Crystal Structure Analysis, Stability Study, and Phase Transformation Behavior15
Recent Update on Bacteria as a Delivery Carrier in Cancer Therapy: From Evil to Allies15
Spray Dried Rugose Lipid Particle Platform for Respiratory Drug Delivery15
A Hollow Microneedle Equipped with a Micropillar for Improved Needle Insertion and Injection of Drug Solution15
Aerosolizable Plasmid DNA Dry Powders Engineered by Thin-film Freezing15
Improvement of Workflows and Assay Reproducibility by The Introduction of “Assay-Ready” Culturing of MDCK Cells for Transport Studies15
Development of a Once-Daily Modified-Release Formulation for the Short Half-Life RIPK1 Inhibitor GSK2982772 using DiffCORE Technology15
miRNA Signature of Urine Extracellular Vesicles Shows the Involvement of Inflammatory and Apoptotic Processes in Diabetic Chronic Kidney Disease15
Enhancing the Stability, Solubility, and Antioxidant Activity of Cinchonine through Pharmaceutical Cocrystallization15
Development of an Accelerated Rotator-based Drug Release Method for the Evaluation of Bupivacaine Multivesicular Liposomes15
Pharmacokinetic Profile of Brepocitinib with Topical Administration in Atopic Dermatitis and Psoriasis Populations: Strategy to Inform Clinical Trial Design in Adult and Pediatric Populations15
Potential Application of Exosomes in Vaccine Development and Delivery15
Roles and Application of Extracellular Vesicles Occurring Endogenously and Naturally15
Co-delivery of Brinzolamide and Timolol from Micelles-laden Contact Lenses: In vitro and In Vivo Evaluation15
Evaluation of Encequidar as An Intestinal P-gp and BCRP Specific Inhibitor to Assess the Role of Intestinal P-gp and BCRP in Drug-Drug Interactions15
Discovery of the Next Generation of Non-peptidomimetic Neurolysin Activators with High Blood-Brain Barrier Permeability: a Pharmacokinetics Study in Healthy and Stroke Animals14
Preclinical Toxicity Study and Tissue Distribution of YSCH- 01 Injection via Intratumoral Injection, Intravenous Injection, and Intraperitoneal Injection in Syrian Hamsters14
Validation of Anti-Adeno Associated Virus Serotype rh10 (AAVrh.10) Total and Neutralizing Antibody Immunogenicity Assays14
Characteristics of Tylvalosin Tartrate Enteric Amorphous Pellets Prepared by Liquid Layering14
Retraction Note to: Nanoformulation of Apolipoprotein E3-Tagged Liposomal Nanoparticles for the Co-Delivery of KRAS-siRNA and Gemcitabine for Pancreatic Cancer Treatment14
Research Landscape of Physiologically Based Pharmacokinetic Model Utilization in Different Fields: A Bibliometric Analysis (1999–2023)14
Physiologically Based Pharmacokinetic Modeling for Prediction of 5-FU Pharmacokinetics in Cancer Patients with Hepatic Impairment After 5-FU and Capecitabine Administration14
Meta-Analysis of Drug Delivery Approaches for Treating Intracellular Infections14
Retraction Note: Combination Cancer Immunotherapy with Dendritic Cell Vaccine and Nanoparticles Loaded with Interleukin-15 and Anti-beta-catenin siRNA Significantly Inhibits Cancer Growth and Induces 14
Evaluation of Pharmacokinetic and Pharmacodynamic (PK/PD) of Novel Fluorenylmethoxycarbonyl- Phenylalanine Antimicrobial Agent14
Biodistribution and Non-linear Gene Expression of mRNA LNPs Affected by Delivery Route and Particle Size14
Inhalable N-Acetylcysteine-loaded Lactose-coated PLGA Nanoparticles for Tuberculosis Treatment13
Structure and Function of Cationic and Ionizable Lipids for Nucleic Acid Delivery13
An Enthalpy-Balance Model for Timewise Evolution of Temperature during Wet Stirred Media Milling of Drug Suspensions13
Modeling Multiphase Heat and Mass Transfer in an Agitated Filter Dryer by Integrating Experiment, Computations, and Analytical Solutions13
A New Analytical LC–MS/MS Method for Determination of Eight Standard Nitrosamines (NDMA, NMBA, NDEA, NEIPA, NDIPA, NMPA, NDPA, NDBA) in a Commercial Small Molecule Drug Product Capsules and its Active13
Use of Flory–Huggins Interaction Parameter and Contact Angle Values to Predict the Suitability of the Drug-Polymer System for the Production and Stability of Nanosuspensions13
Impact of Select Geometric and Operational Parameters on Hydrodynamics in Dissolution Apparatus 2 (Paddle Apparatus): A Design of Experiments Analysis Based on Computational Fluid Dynamics Simulations13
Incorporating Uremic Solute-mediated Inhibition of OAT1/3 Improves PBPK Prediction of Tenofovir Renal and Systemic Disposition in Patients with Severe Kidney Disease13
Cefmetazole as an Alternative to Carbapenems Against Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Infections Based on In Vitro and In Vivo Pharmacokinetics/Pharmacodynamics Experiments13
Correlative Image-Based Release Prediction and 3D Microstructure Characterization for a Long Acting Parenteral Implant13
Mechanism of Insoluble Aggregate Formation in a Reconstituted Solution of Spray-Dried Protein Powder13
Development of Candesartan Cilexetil-sodium Carbonate Anhydrate-mesoporous Silica Solid Dispersion in Polymer-free System13
Identification of the specific causes of polysorbate 20 degradation in monoclonal antibody formulations containing multiple lipases13
Dissolution Profiles of Carbamazepine Cocrystals with Cis–Trans Isomeric Coformers13
Reference Standards to Support Quality of Synthetic Peptide Therapeutics12
Critical Needs and Opportunities for Advanced Manufacturing of Lyophilized Injectables12
Evaluation of Two Cosolvency Models to Predict Solute Partitioning between Polymers (LDPE) and Water - Ethanol Simulating Solvent Mixtures12
Dissolution Profiles Comparison Using Various Model Independent Statistical Approaches: Can We Increase Chance of Similarity?12
Influence of Milling Parameters on Crystal Morphology, Thermal Behavior, and Dissolution of Mesalamine Nanocrystals12
The Impact of Post-Processing Temperature on PLGA Microparticle Properties12
In vivo Pharmacokinetic/Pharmacodynamic Analysis of the Efficacy of the Cefepime/Nacubactam Combination Against β-Lactamase-Producing Enterobacterales based on the Instantaneous MIC Concept12
Novel Self-Assembled Micelles With Increased Tumor Penetration and Anti-Tumor Efficiency Against Breast Cancer12
Minimal Physiologically-based Pharmacokinetic Model to Investigate the Effect of Charge on the Pharmacokinetics of Humanized anti-HCV-E2 IgG Antibodies in Sprague–Dawley Rats12
Direct Assessment of Oligomerization of Chemically Modified Peptides and Proteins in Formulations using DLS and DOSY-NMR12
Evaluation of In Vitro Metabolism- and Transporter-Based Drug Interactions with Sunscreen Active Ingredients12
Solubility vs Dissolution in Physiological Bicarbonate Buffer12
Correction: Practical Advice on Scientific Design of Freeze-Drying Process: 2023 Update12
Translation from Preclinical Research to Clinical Trials: Transdermal Drug Delivery for Neurodegenerative and Mental Disorders11
The Acute Impact of Propofol on Blood–Brain Barrier Integrity in Mice11
A Novel Fluoro-Pyrazine-Bridged Donor-Accepter-Donor Fluorescent Probe for Lipid Droplet-Specific Imaging in Diverse Cells and Superoxide Anion Generation11
Preclinical Evaluation of AAV8-R338L Gene Therapy for Hemophilia: Efficacy, Pharmacokinetics, Distribution, Excretion and Toxicity in Mouse Models and Non-human Primates11
Pharmacokinetic Modeling of the Effect of Tariquidar on Ondansetron Disposition into the Central Nervous System11
Rapid Development of High Concentration Protein Formulation Driven by High-Throughput Technologies11
Correction: Effect of Buffer Salts on Physical Stability of Lyophilized and Spray-Dried Protein Formulations Containing Bovine Serum Albumin and Trehalose11
Role of Tissue Hydraulic Permeability in Convection-Enhanced Delivery of Nanoparticle-Encapsulated Chemotherapy Drugs to Brain Tumour11
Directing the Way—Receptor and Chemical Targeting Strategies for Nucleic Acid Delivery11
Impact of Pre-Actuation Shaking on the Aerosolization Performance of Easyhaler® Salbutamol Dry Powder Inhaler11
Osmolality of Excipients for Parenteral Formulation Measured by Freezing Point Depression and Vapor Pressure – A Comparative Analysis11
Raman Spectroscopic Analysis of Highly-Concentrated Antibodies under the Acid-Treated Conditions11
Effect of Particle Size and Surface Charge on Nanoparticles Diffusion in the Brain White Matter11
Enabling Efficient Design of Biological Formulations through Advanced Characterizations11
Co-delivery of gemcitabine and cisplatin via Poly (L-glutamic acid)-g-methoxy poly (ethylene glycol) micelle to improve the in vivo stability and antitumor effect11
Strategies to improve the physicochemical properties of peptide-based drugs11
Scaling Down Large-Scale Thawing of Monoclonal Antibody Solutions: 3D Temperature Profiles, Changes in Concentration, and Density Gradients11
Dextran Mass Ratio Controls Particle Drying Dynamics in a Thermally Stable Dry Powder Vaccine for Pulmonary Delivery11
Effect of Buffer Salts on Physical Stability of Lyophilized and Spray-Dried Protein Formulations Containing Bovine Serum Albumin and Trehalose11
The Role of Artificial Intelligence and Machine Learning in Accelerating the Discovery and Development of Nanomedicine11
Effect of Structurally Related Compounds on Desupersaturation Kinetics of Indomethacin11
Mathematical and Pharmacokinetic Approaches for the Design of New 3D Printing Inks Using Ricobendazole10
Single-dose pharmacokinetics and lung function of nebulized niclosamide ethanolamine in sheep10
Strategies to Stabilize Dalbavancin in Aqueous Solutions; Section-1: the Effects of Metal Ions and Buffers10
Trends in Light and Temperature Sensitivity Recommendations among Licensed Biotechnology Drug Products10
Physiologically Based Biopharmaceutics Model for Selumetinib Food Effect Investigation and Capsule Dissolution Safe Space – Part I: Adults10
Changes in the Fraction Metabolized in Children Younger than Four Years; When is Clearance Scaling for the Dominant Elimination Route in Adults Appropriate?10
Olmesartan niosomes ameliorates the Indomethacin-induced gastric ulcer in rats: Insights on MAPK and Nrf2/HO-1 signaling pathway10
Clinical Investigation of Large Volume Subcutaneous Delivery up to 25 mL for Lean and Non-Lean Subjects10
Intradermal Vaccination with PLGA Nanoparticles via Dissolving Microneedles and Classical Injection Needles10
Sialic Acid-based Glycoconjugation on Myricetin-encapsulated Cationic Nanocarriers for the Treatment of Alzheimer's10
Microneedle Mediated Iontophoretic Delivery of Tofacitinib Citrate10
Challenges and Opportunities for Celecoxib Repurposing10
Shedding Light on the Blood–Brain Barrier Transport with Two-Photon Microscopy In Vivo10
Correction: Leveraging Model Master Files for Long-Acting Injectables10
In Vitro ADME and Preclinical Pharmacokinetics of Ulotaront, a TAAR1/5-HT1A Receptor Agonist for the Treatment of Schizophrenia10
Physiologically Based Pharmacokinetic Model of Brain Delivery of Plasma Protein Bound Drugs10
High Content Image Analysis of Cellular Responses of the Murine J774A.1 Cell Line and Primary Human Cells Alveolar Macrophages to an Extended Panel of Pharmaceutical Agents10
Effects of Intradermal Administration Volume Using a Hollow Microneedle on the Pharmacokinetics of Fluorescein Isothiocyanate Dextran (M.W. 4,000)10
Can Extracellular Vesicles as Drug Delivery Systems Be a Game Changer in Cardiac Disease?9
The Impact of Drug Properties and Severity of Obesity on Renal Drug Clearance Through Glomerular Filtration and Active Tubular Secretion: A Systematic Analysis Using PBPK Modeling9
In-Vivo Tape Stripping Study with Caffeine for Comparisons on Body Sites, Age and Washing9
Vehicles for Drug Administration to Children: Results and Learnings from an In-Depth Screening of FDA-Recommended Liquids and Soft Foods for Product Quality Assessment9
Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy9
Finite Element Modeling of Powder Compaction: Mini-Tablets in Comparison with Conventionally Sized Tablets9
Chemical Distribution Uniformity Assessment of “Intra-Tablet” by Hyperspectral Raman Imaging Analysis9
Revisiting the Effect of Aging on the Transport of Molecules through the Skin9
Predicting Drug-Drug Interactions Involving Rifampicin Using a Semi-mechanistic Hepatic Compartmental Model9
Identification of Four Similar Cell Culture Media According to their Glucose, Glutamine, and Pyruvate Content by Handheld Raman Spectroscopy9
Modeling Dual Drug Delivery from Eluting Stents: The Influence of Non-Linear Binding Competition and Non-Uniform Drug Loading9
Assessment of Escherichia coli-derived Recombinant Human Bone Morphogenic Protein-2 on Fertilization and Early Embryonic Development in Rats9
Comparative Thermodynamics of the Reversible Self-Association of Therapeutic mAbs Reveal Opposing Roles for Linked Proton- and Ion-Binding Events9
Assessment of High-Power Electronic Nicotine Delivery System as an Alternative Aerosol Device for Terbutaline Delivery9
Mechanisms of Crystal Plasticization by Lattice Water9
Evaluation of the Combination of L‑leucine to Chitosan on Sustained Release of Inhalable Heparin Sodium Microparticles9
Pharmacological Innovations in Space: Challenges and Future Perspectives9
Pre-clinical Formulation Development of an in situ Meglumine Salt of AZD5991: A Novel Macrocyclic Mcl-1 Inhibitor9
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