Pharmaceutical Research

Article	Citations
Combating Alcohol Adduct Impurity in Immunosuppressant Drug Product Manufacturing: A Scientific Investigation for Enhanced Process Control	175
Thermo-Responsive Polymer-siRNA Conjugates Enabling Artificial Control of Gene Silencing around Body Temperature	165
Analytical Workflows to Unlock Predictive Power in Biotherapeutic Developability	130
Modeling Gasotransmitter Availability to Brain Capillary Endothelial Cells with Ultrasound-sensitive Microbubbles	108
In Vitro and In Silico Investigations on Drug Delivery in the Mouth-Throat Models with Handihaler®	91
A Comprehensive Design-to-skin Pipeline to Fabricate Polymeric Microneedles Using Ultrahigh-resolution 3D Printing	82
Cationic Ester Prodrugs of Curcumin with N,N-dimethyl Amino Acid Promoieties Improved Poor Water Solubility and Intestinal Absorption	78
Pharmacokinetic Assessment of Drug Efflux from Erythrocytes Loaded with Corticosteroid Esters	74
Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice	64
Computational and Experimental Screening Approaches to Aripiprazole Salt Crystallization	63
Unambiguous Identification of Glucose-Induced Glycation in mAbs and other Proteins by NMR Spectroscopy	54
Brain Targeted Curcumin Loaded Turmeric Oil Microemulsion Protects Against Trimethyltin Induced Neurodegeneration in Adult Zebrafish: A Pharmacokinetic and Pharmacodynamic Insight	52
Drug Release from Surfactant-Containing Amorphous Solid Dispersions: Mechanism and Role of Surfactant in Release Enhancement	49
Development of Amorphous Solid Dispersion Sustained-Release Formulations with Polymer Composite Matrix-Regulated Stable Release Plateaus	49
Engineering a Remedy to Modulate and Optimize Biopharmaceutical Properties of Rebamipide by Synthesizing New Cocrystal: In Silico and Experimental Studies	46
Discovery and Control of Succinimide Formation and Accumulation at Aspartic Acid Residues in The Complementarity-Determining Region of a Therapeutic Monoclonal Antibody	44
Perspectives on the Wetting of Solids in Pharmaceutical Systems	43
Relative Performance of Volume of Distribution Prediction Methods for Lipophilic Drugs with Uncertainty in LogP Value	43
Novel Deep Eutectic Solvent–Hydrogel Systems for Synergistic Transdermal Delivery of Chinese Herb Medicine and Local Treatments for Rheumatoid Arthritis	42
Safety and Pharmacokinetics of Intranasally Administered Heparin	41
Ritonavir-Boosted Exposure of Kinase Inhibitors: an Open Label, Cross-over Pharmacokinetic Proof-of-Concept Trial with Erlotinib	40
Limited Impact of Murine Placental MDR1 on Fetal Exposure of Certain Drugs Explained by Bypass Transfer Between Adjacent Syncytiotrophoblast Layers	40
Utilizing Octanoic Acid to Quantitatively Assess the Oxidation Status of PS80	39
Professor Margareta Hammarlund-Udenaes – a Modern and Visionary Mentor	39
Revolutionizing Heart Failure Therapy: Harnessing IVT mRNA and Fusion Protein Technology to Prolong rhBNP Half-Life	38

Cortisol as Biomarker for CYP17-Inhibition is Associated with Therapy Outcome of Abiraterone Acetate	38
Learning Chemotherapy Drug Action via Universal Physics-Informed Neural Networks	37
Correction: A Preformulation Experiment: The Influence of Poloxamer 188 and Poloxamer 407 on the Binding Coefficients (Single Molecule) and the Partitioning Coefficients (Micelle) of Ketoprofen (Probe	37
Controlling Gastric Delivery of a GIP/GLP1 Peptide in Monkeys by Mucoadhesive SNAC Tablets	37
PEGylation of Propofol Reduces Its Adsorption to Extracorporeal Membrane Oxygenator (ECMO) Components	37
Modulation of Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway in Gastrointestinal Cancers by Phytochemicals	36
Role of Disease Progression Models in Drug Development	35
Therapeutic Potential of Semaglutide, a Newer GLP-1 Receptor Agonist, in Abating Obesity, Non-Alcoholic Steatohepatitis and Neurodegenerative diseases: A Narrative Review	34
Advancements in Particle Engineering for Inhalation Delivery of Small Molecules and Biotherapeutics	34
Photo-Oxidation Mechanisms in Liquid Pharmaceutical Formulations: The Overlooked Role of Singlet Oxygen Presented as a Case Study	34
Delivery of Corn-Derived Nanoparticles with Anticancer Activity to Tumor Tissues by Modification with Polyethylene Glycol for Cancer Therapy	34
Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells	34
Enhanced Penetration and Retention of an Antibody in the Articular Cartilage Through Aggrecan Binding and Molecular Downsizing	33
A Novel Combination Therapy of Erythropoietin and Thrombopoietin to Treat Erythropoietin-Resistance anemia	33
Design of an Ante-enhancer with an Azone-Mimic Structure using Ionic Liquid	33
Coupling Drug Dissolution with BCS	33
Editorial Expression of Concern: Regulation of miR-19 to Breast Cancer Chemoresistance Through Targeting PTEN	33
Peptide Acylation in Aliphatic Polyesters: a Review of Mechanisms and Inhibition Strategies	32
PAMAM versus PEI complexation for siRNA delivery: interaction with model lipid membranes and cellular uptake	32
Generic Enrichment Method for Liquid Chromatography-Multiple Reaction Monitoring-Mass Spectrometry Assay for Quantitative Measurement of Biological Therapeutics in Serum	31
Modification of Peptide and Permeation Enhancer In Vitro Release Rates by Dispersion with a Gel-Forming Polymer	31
Design Considerations for Intratracheal Delivery Devices to Achieve Proof-of-Concept Dry Powder Biopharmaceutical Delivery in Mice	31
Temperature and Heat Transfer Control During Freeze Drying. Effect of Vial Holders and Influence of Pressure	30
Physiologically-Based Pharmacokinetic Modeling of PAXLOVID™ with First-Order Absorption Kinetics	30
Phase Transitions Involving Channel Hydrates of a New Pharmaceutical Compound	30
Investigation of an Uncommon Artifact during Reducing Capillary Electrophoresis-Sodium Dodecyl Sulfate Analysis of a Monoclonal Antibody with Dynamic Light Scattering and Reversed Phase High-Performan	30
Novel Pharmaceutical Cocrystals of Tegafur: Synthesis, Performance, and Theoretical Studies	30
Topical Semisolid Drug Product Critical Quality Attributes with Relevance to Cutaneous Bioavailability and Pharmacokinetics: Part I—Bioequivalence of Acyclovir Topical Creams	29
Microdialysis of Drug and Drug Metabolite: a Comprehensive In Vitro Analysis for Voriconazole and Voriconazole N-oxide	28
Optimization of Vancomycin Initial Dose in Term and Preterm Neonates by Machine Learning	28
Improved Pharmaceutical Properties of Honokiol via Salification with Meglumine: an Exception to Oft-quoted ∆pKa Rule	27
Multiphysics Modelling and Simulation of Thrombolysis via Activated Platelet-Targeted Nanomedicine	27
Oral Delivery of Nucleic Acid Therapies for Local and Systemic Action	27
Model-Guided Development of a Semi-Continuous Drying Process	27
A Tale of Two Stressors in Biologic Drug Product Development: Shaking Mode and Primary Packaging	27
Strategy for Cytoplasmic Delivery Using Inorganic Particles	27
Retraction Note: Characterization of Preclinical Pharmacokinetic Properties and Prediction of Human PK Using a Physiologically Based Pharmacokinetic Model for a Novel Anti-Arrhythmic Agent Sulcardine	26
Elucidating the Impact of Material Properties on Tablet Manufacturability for Binary Paracetamol Blends	26
N-terminus of Etanercept is Proteolytically Processed by Dipeptidyl Peptidase-4	25
The Osmolality and Hemolysis of High-Concentration Monoclonal Antibody Formulations	25
Formulation and Validation of an Extended Sigmoid Emax Model in Pharmacodynamics	25
Correction to: Re-examining digoxin bioavailability after half a century: Time for changes in the bioavailability concepts	25
Evaluation of Blood-CSF Barrier Transport by Quantitative Real Time Fluorescence Microscopy	25
Natural Powerhouse Duo: Hierarchical Levan Hydrogels with Nanoencapsulated Cannabidiol as Local Delivery Systems	24
Development and Evaluation of Dual Microneedle Array Patch for Sequential Intradermal Delivery of Adjuvant and Antigen	24
Progress in the Application of Microneedles in Eye Disorders and the Proposal of the Upgraded Microneedle with Spinule	24
Predictive Value of Vancomycin AUC24/MIC Ratio for 30-day Mortality in Patients with Severe or Complicated Methicillin-Resistant Staphylococcus aureus Infections: A Multicenter Retrospective Study	24
Nanobody-Oligonucleotide Conjugates (NucleoBodies): The Next Frontier in Oligonucleotide Therapy	23
Sensitivity and Uncertainty Analysis of Micro-Flow Imaging for Sub-Visible Particle Measurements Using Artificial Neural Network	23
Hydration Mechanism and Its Effect on the Solubility of Aripiprazole	23

Decrease in In Vivo Efflux Transport via P-glycoprotein at the Rat Inner Blood-Retinal Barrier by Peripheral Administration of Lipopolysaccharide	23
Application of Twin-Screw Melt Granulation to Overcome the Poor Tabletability of a High Dose Drug	23
Application of PAT Probes in Aluminum Phosphate Adjuvant Manufacturing	22
Dissolution Profiles of Poorly Soluble Drug Salts in Bicarbonate Buffer	22
Correction to: Liposomal Formulation for Oral Delivery of Cyclosporine A: Usefulness as a Semisolid-Dispersion System	22
Amyloid Light Chain Proteins in Cardiovascular Disease: Pathogenesis and Emerging Therapies for Cardiac Amyloidosis	22
Local Delivery of Non-opioid Analgesic Microparticles to Modulate Post-surgical Pain	21
Convolutional Neural Networks Guided Raman Spectroscopy as a Process Analytical Technology (PAT) Tool for Monitoring and Simultaneous Prediction of Monoclonal Antibody Charge Variants	21
A Model-Based Evaluation of Noninvasive Biomarkers to Reflect Histological Nonalcoholic Fatty Liver Disease Scores	20
Numerical Investigation to Improve Pulmonary Drug Delivery via Dry Powder Inhalers: A Review of In-Silico Modeling	20
Understanding the Phagocytosis of Particles: the Key for Rational Design of Vaccines and Therapeutics	20
An Evaluation of Wet Granulation Process Selection for API Prone to Polymorphic Form Conversion in the Presence of Moisture and Heat	20
Efficient Cytosolic Delivery of siRNA Using Lyophilized and Reconstituted Polymer-siRNA Polyplexes	20
Fluorinated PAMAM-Arginine Carrier Prodrugs for pH-Sensitive Sustained Ibuprofen Delivery	20
Assessment of Minipigs as a Non-clinical Model for Screening and Derisking Injection Site Reactions in Clinical Trials	20
Impostor Phenomenon and Grit as Predictors of Job Satisfaction in Female Pharmacy Faculty	20
Accelerating Process Development and Product Formulation	19
Microneedle-Mediated Permeation Enhancement of Chlorhexidine Digluconate: Mechanistic Insights Through Imaging Mass Spectrometry	18
Development of a New Dry Powder Aerosol Synthetic Lung Surfactant Product for Neonatal Respiratory Distress Syndrome (RDS) – Part II: In vivo Efficacy Testing in a Rabbit Surfactant Washout Model	18
In Vitro-In Vivo Correlation Of Amorphous Solid Dispersion Enabled Itraconazole Tablets	18
Consideration of Fractional Distribution Parameter fd in the Chen and Gross Method for Tissue-to-Plasma Partition Coefficients: Comparison of Several Methods	18
Time-Lapse Macro Imaging with Dissolution Tests for Exploring the Interrelationship Between Disintegration and Dissolution Behaviors of Solid Dosages	18
Coformer-Dependent Physical Stability in a Series of Naringenin-Based Coamorphous Materials with Caffeine, Theophylline, and Theobromine	18
Development of a Physiologically-Based Pharmacokinetic Model for Whole-Body Disposition of MMAE Containing Antibody-Drug Conjugate in Mice	17
Application of Confocal Raman Microscopy for the Characterization of Topical Semisolid Formulations and their Penetration into Human Skin Ex Vivo	17
Acetylcholine Analog-Modified Albumin Nanoparticles for the Enhanced and Synchronous Brain Delivery of Saponin Components of Panax Notoginseng	17
N-oxidation Regioselectivity and Risk Prediction Using DFT-ALIE Calculations	17
Optimization of Lung Surfactant Coating of siRNA Polyplexes for Pulmonary Delivery	17
Ionic Liquids: Emerging Antimicrobial Agents	17
Freeze-Dried Biopharmaceutical Formulations are Surprisingly Less Stable than Liquid Formulations during Dropping	16
Pharmacokinetic Profile of Brepocitinib with Topical Administration in Atopic Dermatitis and Psoriasis Populations: Strategy to Inform Clinical Trial Design in Adult and Pediatric Populations	16
Development of an Accelerated Rotator-based Drug Release Method for the Evaluation of Bupivacaine Multivesicular Liposomes	16
Differences in Pharmacokinetic/Pharmacodynamic Parameters of Tedizolid Against VRE and MRSA	16
Adopting the Model Master File Framework to Enhance Modeling and Simulations Approaches for Regulatory Use	16
Polymorphism of Pradofloxacin: Crystal Structure Analysis, Stability Study, and Phase Transformation Behavior	16
Leveraging Model Master Files from a Technology Company Perspective: Facilitating Quantitative Medicine in Regulatory Frameworks	16
Development of a Once-Daily Modified-Release Formulation for the Short Half-Life RIPK1 Inhibitor GSK2982772 using DiffCORE Technology	16
Spray Dried Rugose Lipid Particle Platform for Respiratory Drug Delivery	16
A Hollow Microneedle Equipped with a Micropillar for Improved Needle Insertion and Injection of Drug Solution	15
Enhancing the Stability, Solubility, and Antioxidant Activity of Cinchonine through Pharmaceutical Cocrystallization	15
A Semi-Physiological Three-Compartment Model Describes Brain Uptake Clearance and Efflux of Sucrose and Mannitol after IV Injection in Awake Mice	15
Applications of Model Informed Drug Development (MIDD) in Drug Development Lifecycle and Regulatory Review	15
Evaluation of Encequidar as An Intestinal P-gp and BCRP Specific Inhibitor to Assess the Role of Intestinal P-gp and BCRP in Drug-Drug Interactions	15
Recent Update on Bacteria as a Delivery Carrier in Cancer Therapy: From Evil to Allies	15
Roles and Application of Extracellular Vesicles Occurring Endogenously and Naturally	15
Potential Application of Exosomes in Vaccine Development and Delivery	15
miRNA Signature of Urine Extracellular Vesicles Shows the Involvement of Inflammatory and Apoptotic Processes in Diabetic Chronic Kidney Disease	15
Inhalable N-Acetylcysteine-loaded Lactose-coated PLGA Nanoparticles for Tuberculosis Treatment	14
Improvement of Workflows and Assay Reproducibility by The Introduction of “Assay-Ready” Culturing of MDCK Cells for Transport Studies	14
Characteristics of Tylvalosin Tartrate Enteric Amorphous Pellets Prepared by Liquid Layering	14
Retraction Note: Combination Cancer Immunotherapy with Dendritic Cell Vaccine and Nanoparticles Loaded with Interleukin-15 and Anti-beta-catenin siRNA Significantly Inhibits Cancer Growth and Induces	14
Incorporating Uremic Solute-mediated Inhibition of OAT1/3 Improves PBPK Prediction of Tenofovir Renal and Systemic Disposition in Patients with Severe Kidney Disease	14
Use of Flory–Huggins Interaction Parameter and Contact Angle Values to Predict the Suitability of the Drug-Polymer System for the Production and Stability of Nanosuspensions	14
Co-delivery of Brinzolamide and Timolol from Micelles-laden Contact Lenses: In vitro and In Vivo Evaluation	14
Aerosolizable Plasmid DNA Dry Powders Engineered by Thin-film Freezing	14
Evaluation of Pharmacokinetic and Pharmacodynamic (PK/PD) of Novel Fluorenylmethoxycarbonyl- Phenylalanine Antimicrobial Agent	14
Direct Assessment of Oligomerization of Chemically Modified Peptides and Proteins in Formulations using DLS and DOSY-NMR	14
Preclinical Toxicity Study and Tissue Distribution of YSCH- 01 Injection via Intratumoral Injection, Intravenous Injection, and Intraperitoneal Injection in Syrian Hamsters	14
Retraction Note to: Nanoformulation of Apolipoprotein E3-Tagged Liposomal Nanoparticles for the Co-Delivery of KRAS-siRNA and Gemcitabine for Pancreatic Cancer Treatment	14
Biodistribution and Non-linear Gene Expression of mRNA LNPs Affected by Delivery Route and Particle Size	14
Discovery of the Next Generation of Non-peptidomimetic Neurolysin Activators with High Blood-Brain Barrier Permeability: a Pharmacokinetics Study in Healthy and Stroke Animals	14
Physiologically Based Pharmacokinetic Modeling for Prediction of 5-FU Pharmacokinetics in Cancer Patients with Hepatic Impairment After 5-FU and Capecitabine Administration	14
Development of Candesartan Cilexetil-sodium Carbonate Anhydrate-mesoporous Silica Solid Dispersion in Polymer-free System	13
A New Analytical LC–MS/MS Method for Determination of Eight Standard Nitrosamines (NDMA, NMBA, NDEA, NEIPA, NDIPA, NMPA, NDPA, NDBA) in a Commercial Small Molecule Drug Product Capsules and its Active	13
Influence of Milling Parameters on Crystal Morphology, Thermal Behavior, and Dissolution of Mesalamine Nanocrystals	13
Modeling Multiphase Heat and Mass Transfer in an Agitated Filter Dryer by Integrating Experiment, Computations, and Analytical Solutions	13
Identification of the specific causes of polysorbate 20 degradation in monoclonal antibody formulations containing multiple lipases	13
Dissolution Profiles of Carbamazepine Cocrystals with Cis–Trans Isomeric Coformers	13
Reference Standards to Support Quality of Synthetic Peptide Therapeutics	13
An Enthalpy-Balance Model for Timewise Evolution of Temperature during Wet Stirred Media Milling of Drug Suspensions	13
Mechanism of Insoluble Aggregate Formation in a Reconstituted Solution of Spray-Dried Protein Powder	13
The Impact of Post-Processing Temperature on PLGA Microparticle Properties	13
Validation of Anti-Adeno Associated Virus Serotype rh10 (AAVrh.10) Total and Neutralizing Antibody Immunogenicity Assays	13
Critical Needs and Opportunities for Advanced Manufacturing of Lyophilized Injectables	13
Meta-Analysis of Drug Delivery Approaches for Treating Intracellular Infections	13
Research Landscape of Physiologically Based Pharmacokinetic Model Utilization in Different Fields: A Bibliometric Analysis (1999–2023)	13
Impact of Select Geometric and Operational Parameters on Hydrodynamics in Dissolution Apparatus 2 (Paddle Apparatus): A Design of Experiments Analysis Based on Computational Fluid Dynamics Simulations	13
Correction: Practical Advice on Scientific Design of Freeze-Drying Process: 2023 Update	12
Impact of Pre-Actuation Shaking on the Aerosolization Performance of Easyhaler® Salbutamol Dry Powder Inhaler	12
Structure and Function of Cationic and Ionizable Lipids for Nucleic Acid Delivery	12

Osmolality of Excipients for Parenteral Formulation Measured by Freezing Point Depression and Vapor Pressure – A Comparative Analysis	12
In vivo Pharmacokinetic/Pharmacodynamic Analysis of the Efficacy of the Cefepime/Nacubactam Combination Against β-Lactamase-Producing Enterobacterales based on the Instantaneous MIC Concept	12
Minimal Physiologically-based Pharmacokinetic Model to Investigate the Effect of Charge on the Pharmacokinetics of Humanized anti-HCV-E2 IgG Antibodies in Sprague–Dawley Rats	12
A Novel Fluoro-Pyrazine-Bridged Donor-Accepter-Donor Fluorescent Probe for Lipid Droplet-Specific Imaging in Diverse Cells and Superoxide Anion Generation	12
Evaluation of In Vitro Metabolism- and Transporter-Based Drug Interactions with Sunscreen Active Ingredients	12
Solubility vs Dissolution in Physiological Bicarbonate Buffer	11
The Acute Impact of Propofol on Blood–Brain Barrier Integrity in Mice	11
Novel Self-Assembled Micelles With Increased Tumor Penetration and Anti-Tumor Efficiency Against Breast Cancer	11
Rapid Development of High Concentration Protein Formulation Driven by High-Throughput Technologies	11
Enabling Efficient Design of Biological Formulations through Advanced Characterizations	11
Raman Spectroscopic Analysis of Highly-Concentrated Antibodies under the Acid-Treated Conditions	11
Co-delivery of gemcitabine and cisplatin via Poly (L-glutamic acid)-g-methoxy poly (ethylene glycol) micelle to improve the in vivo stability and antitumor effect	11
Correction: Leveraging Model Master Files for Long-Acting Injectables	11
Effect of Buffer Salts on Physical Stability of Lyophilized and Spray-Dried Protein Formulations Containing Bovine Serum Albumin and Trehalose	11
Evaluation of Two Cosolvency Models to Predict Solute Partitioning between Polymers (LDPE) and Water - Ethanol Simulating Solvent Mixtures	11
Strategies to improve the physicochemical properties of peptide-based drugs	11
Effect of Particle Size and Surface Charge on Nanoparticles Diffusion in the Brain White Matter	11
Dextran Mass Ratio Controls Particle Drying Dynamics in a Thermally Stable Dry Powder Vaccine for Pulmonary Delivery	11
Effect of Structurally Related Compounds on Desupersaturation Kinetics of Indomethacin	11
Translation from Preclinical Research to Clinical Trials: Transdermal Drug Delivery for Neurodegenerative and Mental Disorders	11
Directing the Way—Receptor and Chemical Targeting Strategies for Nucleic Acid Delivery	11
Preclinical Evaluation of AAV8-R338L Gene Therapy for Hemophilia: Efficacy, Pharmacokinetics, Distribution, Excretion and Toxicity in Mouse Models and Non-human Primates	11
Role of Tissue Hydraulic Permeability in Convection-Enhanced Delivery of Nanoparticle-Encapsulated Chemotherapy Drugs to Brain Tumour	11
Dissolution Profiles Comparison Using Various Model Independent Statistical Approaches: Can We Increase Chance of Similarity?	11
The Role of Artificial Intelligence and Machine Learning in Accelerating the Discovery and Development of Nanomedicine	11
Bionanoconjugates in Neurodegeneration: Peptide–Nanoparticle Alliances for Next-Generation Therapies	11
Correction: Effect of Buffer Salts on Physical Stability of Lyophilized and Spray-Dried Protein Formulations Containing Bovine Serum Albumin and Trehalose	11
Pharmacokinetic Modeling of the Effect of Tariquidar on Ondansetron Disposition into the Central Nervous System	11
Changes in the Fraction Metabolized in Children Younger than Four Years; When is Clearance Scaling for the Dominant Elimination Route in Adults Appropriate?	10
Mathematical and Pharmacokinetic Approaches for the Design of New 3D Printing Inks Using Ricobendazole	10
Single-dose pharmacokinetics and lung function of nebulized niclosamide ethanolamine in sheep	10
Physiologically Based Pharmacokinetic Model of Brain Delivery of Plasma Protein Bound Drugs	10
Microneedle Mediated Iontophoretic Delivery of Tofacitinib Citrate	10
Shedding Light on the Blood–Brain Barrier Transport with Two-Photon Microscopy In Vivo	10
Can Extracellular Vesicles as Drug Delivery Systems Be a Game Changer in Cardiac Disease?	10
Trends in Light and Temperature Sensitivity Recommendations among Licensed Biotechnology Drug Products	10
Strategies to Stabilize Dalbavancin in Aqueous Solutions; Section-1: the Effects of Metal Ions and Buffers	10
Physiologically Based Biopharmaceutics Model for Selumetinib Food Effect Investigation and Capsule Dissolution Safe Space – Part I: Adults	10
High Content Image Analysis of Cellular Responses of the Murine J774A.1 Cell Line and Primary Human Cells Alveolar Macrophages to an Extended Panel of Pharmaceutical Agents	10
In Vitro ADME and Preclinical Pharmacokinetics of Ulotaront, a TAAR1/5-HT1A Receptor Agonist for the Treatment of Schizophrenia	10
Clinical Investigation of Large Volume Subcutaneous Delivery up to 25 mL for Lean and Non-Lean Subjects	10
Sialic Acid-based Glycoconjugation on Myricetin-encapsulated Cationic Nanocarriers for the Treatment of Alzheimer's	10
Effects of Intradermal Administration Volume Using a Hollow Microneedle on the Pharmacokinetics of Fluorescein Isothiocyanate Dextran (M.W. 4,000)	10
Challenges and Opportunities for Celecoxib Repurposing	10
Intradermal Vaccination with PLGA Nanoparticles via Dissolving Microneedles and Classical Injection Needles	10
DeepSeek-LLM with Adaptive RAG for Pharmaceutical Dissolution Prediction	9
Mechanisms of Crystal Plasticization by Lattice Water	9
Predicting Drug-Drug Interactions Involving Rifampicin Using a Semi-mechanistic Hepatic Compartmental Model	9
Pre-clinical Formulation Development of an in situ Meglumine Salt of AZD5991: A Novel Macrocyclic Mcl-1 Inhibitor	9
Evaluation of the Combination of L‑leucine to Chitosan on Sustained Release of Inhalable Heparin Sodium Microparticles	9
In-Silico Modelling of Transdermal Delivery of Macromolecule Drugs Assisted by a Skin Stretching Hypobaric Device	9
Inhaled Indomethacin-Loaded Liposomes as Potential Therapeutics against Non-Small Cell Lung Cancer (NSCLC)	9
Identification of Four Similar Cell Culture Media According to their Glucose, Glutamine, and Pyruvate Content by Handheld Raman Spectroscopy	9
Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy	9
In-Vivo Tape Stripping Study with Caffeine for Comparisons on Body Sites, Age and Washing	9
Assessment of Escherichia coli-derived Recombinant Human Bone Morphogenic Protein-2 on Fertilization and Early Embryonic Development in Rats	9
Revisiting the Effect of Aging on the Transport of Molecules through the Skin	9
Effect of “In Use” Administration on Topical Product Metamorphosis and Skin Permeation of Acyclovir Creams: Implications for Bioequivalence	9
Characterization of mRNA Lipid Nanoparticles by Electron Density Mapping Reconstruction: X-ray Scattering with Density from Solution Scattering (DENSS) Algorithm	9
Modeling Dual Drug Delivery from Eluting Stents: The Influence of Non-Linear Binding Competition and Non-Uniform Drug Loading	9
The Impact of Drug Properties and Severity of Obesity on Renal Drug Clearance Through Glomerular Filtration and Active Tubular Secretion: A Systematic Analysis Using PBPK Modeling	9
Finite Element Modeling of Powder Compaction: Mini-Tablets in Comparison with Conventionally Sized Tablets	9
Chemical Distribution Uniformity Assessment of “Intra-Tablet” by Hyperspectral Raman Imaging Analysis	9
Comparative Thermodynamics of the Reversible Self-Association of Therapeutic mAbs Reveal Opposing Roles for Linked Proton- and Ion-Binding Events	9
Translational Modeling Identifies Synergy between Nanoparticle-Delivered miRNA-22 and Standard-of-Care Drugs in Triple-Negative Breast Cancer	9
Optimisation of Pharmaceutical Cocrystal Dissolution Performance through a Synergistic Precipitation Inhibition	9
Pharmacological Innovations in Space: Challenges and Future Perspectives	9