Pharmaceutical Research

Article	Citations
Activation of Inflammation by MCF-7 Cells-Derived Small Extracellular Vesicles (sEV): Comparison of Three Different Isolation Methods of sEV	123
Advanced Manufacturing, Modeling And Analytical Tools In Injectable Products	119
Phytochemicals and their Nanoformulations for Overcoming Drug Resistance in Head and Neck Squamous Cell Carcinoma	111
Characteristics of Tylvalosin Tartrate Enteric Amorphous Pellets Prepared by Liquid Layering	95
Development of a Melting Point Depression Method to Measure the Solubility of a Small-Molecule Drug in Poly-Lactic-co-Glycolic Acid (PLGA)	84
Clinical Evaluation of the Temperature Dependence of Subcutaneous Injection Experience in Healthy Volunteers	64
Remodeling of Adipose Tissues by Fatty Acids: Mechanistic Update on Browning and Thermogenesis by n-3 Polyunsaturated Fatty Acids	62
Development of CD133 Targeting Multi-Drug Polymer Micellar Nanoparticles for Glioblastoma - In Vitro Evaluation in Glioblastoma Stem Cells	57
Relative Performance of Volume of Distribution Prediction Methods for Lipophilic Drugs with Uncertainty in LogP Value	56
Retraction Note to: Nanoformulation of Apolipoprotein E3-Tagged Liposomal Nanoparticles for the Co-Delivery of KRAS-siRNA and Gemcitabine for Pancreatic Cancer Treatment	52
Combating Alcohol Adduct Impurity in Immunosuppressant Drug Product Manufacturing: A Scientific Investigation for Enhanced Process Control	47
Mechanistic Insights into Amorphous Solid Dispersions: Bridging Theory and Practice in Drug Delivery	47
Asiatic Acid Fabricated Nanoconstructs to Mitigate Amyloid Beta1-42 Induced Injury in SH-SY5Y Cells In-Vitro and Ameliorates Cognitive Impairment by Dual Cholinesterase Inhibition and Attenuation of O	42
Tacrolimus-Eluting Disk within the Allograft Enables Vascularized Composite Allograft Survival with Site-Specific Immunosuppression without Systemic Toxicity	41
Fabrication of Polymeric Microneedles using Novel Vacuum Compression Molding Technique for Transdermal Drug Delivery	41
An Enthalpy-Balance Model for Timewise Evolution of Temperature during Wet Stirred Media Milling of Drug Suspensions	37
In Vitro and In Silico Investigations on Drug Delivery in the Mouth-Throat Models with Handihaler®	35
High-Throughput Fluorometric Assay For Quantifying Polysorbate In Biopharmaceutical Products Using Micelle Activated Fluorescence Probe N-Phenyl-1-Naphthylamine	35
Ionic Liquids-Based Drug Delivery: a Perspective	35
Impact of Primary Container Closure System on PS80 Oxidation and the Mechanistic Understanding	35
Impact of Select Geometric and Operational Parameters on Hydrodynamics in Dissolution Apparatus 2 (Paddle Apparatus): A Design of Experiments Analysis Based on Computational Fluid Dynamics Simulations	33
A Perspective on Model-Informed IVIVC for Development of Subcutaneous Injectables	32
Subcutaneous Injection Site Pain of Formulation Matrices	32
Is the One-Compartment Model with First Order Absorption a Useful Approximation?	31
Cationic Ester Prodrugs of Curcumin with N,N-dimethyl Amino Acid Promoieties Improved Poor Water Solubility and Intestinal Absorption	31

Evaluation of Pharmacokinetic and Pharmacodynamic (PK/PD) of Novel Fluorenylmethoxycarbonyl- Phenylalanine Antimicrobial Agent	31
Molecular Dynamics Modeling Based Investigation of the Effect of Freezing Rate on Lysozyme Stability	30
Computational and Experimental Screening Approaches to Aripiprazole Salt Crystallization	30
Advances in Pulmonary Drug Delivery Systems and Inhalation Formulations	30
Keratinocyte Exosomes for Topical Delivery of Tofacitinib in Treatment of Psoriasis: an In Vitro/ In Vivo Study in Animal Model of Psoriasis	30
Computational Fluid Dynamics (CFD) Guided Spray Drying Recommendations for Improved Aerosol Performance of a Small-Particle Antibiotic Formulation	29
Discovery and Control of Succinimide Formation and Accumulation at Aspartic Acid Residues in The Complementarity-Determining Region of a Therapeutic Monoclonal Antibody	28
Analysis of Complex Absorption After Multiple Dosing: Application to the Interaction Between the P-glycoprotein Substrate Talinolol and Rifampicin	28
Exposure–Response Analysis of Osimertinib in EGFR Mutation Positive Non-Small Cell Lung Cancer Patients in a Real-Life Setting	27
Excipient Innovation Through Precompetitive Research	27
Research Landscape of Physiologically Based Pharmacokinetic Model Utilization in Different Fields: A Bibliometric Analysis (1999–2023)	26
A Refined Thin-Film Model for Drug Dissolution Considering Radial Diffusion – Simulating Powder Dissolution	26
Untangling Absorption Mechanisms and Variability in Bioequivalence Studies Using Population Analysis	26
Ritonavir-Boosted Exposure of Kinase Inhibitors: an Open Label, Cross-over Pharmacokinetic Proof-of-Concept Trial with Erlotinib	26
Exploring Multivalency in the Development of Anti-PD-L1 Peptides for Cancer Immunotherapy	26
Limited Impact of Murine Placental MDR1 on Fetal Exposure of Certain Drugs Explained by Bypass Transfer Between Adjacent Syncytiotrophoblast Layers	25
Preferential Oxycodone Loss of Physically Manipulated Abuse Deterrent Oxycodone HCl Extended Release Tablets Prepared for Nasal Insufflation Studies	25
Transcutaneous Delivery of Dexamethasone Sodium Phosphate Via Microneedle-Assisted Iontophoretic Enhancement – A Potential Therapeutic Option for Inflammatory Disorders	25
Effect of mPEG-PLGA on Drug Crystallinity and Release of Long-Acting Injection Microspheres: In Vitro and In Vivo Perspectives	25
Direct Granule Feeding of Thermal Droplet Deposition 3D Printing of Porous Pharmaceutical Solid Dosage Forms Free of Plasticisers	25
Microstructural Characterization of Dry Powder Inhaler Formulations Using Orthogonal Analytical Techniques	24
Analytical Workflows to Unlock Predictive Power in Biotherapeutic Developability	24
Improved Aerosolization Stability of Inhalable Tobramycin Powder Formulation by Co-Spray Drying with Colistin	24
Lipophilic Salts and Lipid-Based Formulations: Enhancing the Oral Delivery of Octreotide	24
Selective COX-2 Inhibitor Etoricoxib’s Liposomal Formulation Attenuates M2 Polarization of TAMs and Enhances its Anti-metastatic Potential	23
Perspectives on the Wetting of Solids in Pharmaceutical Systems	23
Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice	23
The Impact of Post-Processing Temperature on PLGA Microparticle Properties	23
Assessing Dose-Exposure–Response Relationships of Miltefosine in Adults and Children using Physiologically-Based Pharmacokinetic Modeling Approach	23
Development and Validation of Discriminatory In-vitro Release Method for Intramammary Drug Product	23
Topical Solution for Retinal Delivery: Bevacizumab and Ranibizumab Eye Drops in Anti-Aggregation Formula (AAF) in Rabbits	23
An In Silico Platform to Predict Cardiotoxicity Risk of Anti-tumor Drug Combination with hiPSC-CMs Based In Vitro Study	23
Unambiguous Identification of Glucose-Induced Glycation in mAbs and other Proteins by NMR Spectroscopy	22
Machine Learning Prediction of On/Off Target-driven Clinical Adverse Events	22
Retraction Note: Combination Cancer Immunotherapy with Dendritic Cell Vaccine and Nanoparticles Loaded with Interleukin-15 and Anti-beta-catenin siRNA Significantly Inhibits Cancer Growth and Induces	22
Correction: Improvement of Workfows and Assay Reproducibility by The Introduction of “Assay-Ready” Culturing of MDCK Cells for Transport Studie	22
Antimicrobial Activity Classification of Imidazolium Derivatives Predicted by Artificial Neural Networks	22
Development of Amorphous Solid Dispersion Sustained-Release Formulations with Polymer Composite Matrix-Regulated Stable Release Plateaus	22
Bone-Targeted Dual Functional Lipid-coated Drug Delivery System for Osteosarcoma Therapy	21
A Physiology-Based Mathematical Model to Understand Drug Delivery from Contact Lenses to the Back of the Eye	21
Re-visitation of Two Models for Predicting Mechanically-Induced Disordering after Cryogenic Impact Milling	21
Mechanism of Insoluble Aggregate Formation in a Reconstituted Solution of Spray-Dried Protein Powder	21
Discovery of the Next Generation of Non-peptidomimetic Neurolysin Activators with High Blood-Brain Barrier Permeability: a Pharmacokinetics Study in Healthy and Stroke Animals	21
Topical Cream Carrying Drug-Loaded Nanogels for Melanoma Treatment	21
Defining Endocytic Pathways of Fucoidan-Coated PIBCA Nanoparticles from the Design of their Surface Architecture	20
Direct Assessment of Oligomerization of Chemically Modified Peptides and Proteins in Formulations using DLS and DOSY-NMR	20
PBPK/PD Modeling of Nifedipine for Precision Medicine in Pregnant Women: Enhancing Clinical Decision-Making for Optimal Drug Therapy	20
Pharmaceutical Excipients Enhance Iron-Dependent Photo-Degradation in Pharmaceutical Buffers by near UV and Visible Light: Tyrosine Modification by Reactions of the Antioxidant Methionine in Citrate B	20
Drug Release from Surfactant-Containing Amorphous Solid Dispersions: Mechanism and Role of Surfactant in Release Enhancement	20
Advancement of the Infant Air-Jet Dry Powder Inhaler (DPI): Evaluation of Different Positive-Pressure Air Sources and Flow Rates	20

Physiologically Based Pharmacokinetic Modeling for Prediction of 5-FU Pharmacokinetics in Cancer Patients with Hepatic Impairment After 5-FU and Capecitabine Administration	19
Detection of Isopeptide Bonds in Monoclonal Antibody Aggregates	19
Reference Standards to Support Quality of Synthetic Peptide Therapeutics	18
Comprehensive N-Glycan Mapping using Parallel Reaction Monitoring LC–MS/MS	18
Thermo-Responsive Polymer-siRNA Conjugates Enabling Artificial Control of Gene Silencing around Body Temperature	18
Modeling Gasotransmitter Availability to Brain Capillary Endothelial Cells with Ultrasound-sensitive Microbubbles	18
Surface Ligand Valency and Immunoliposome Binding: when More Is Not Always Better	18
An Update on Potential Molecular Biomarkers of Dietary Phytochemicals Targeting Lung Cancer Interception and Prevention	18
Safety and Pharmacokinetics of Intranasally Administered Heparin	18
Insights into Thermal Interactions in Frozen Pharmaceutical Vials: Effects on Ice Nucleation Times and Inhibition	17
Understanding Formulation and Temperature Effects on Dermal Transport Kinetics by IVPT and Multiphysics Simulation	17
Formulation Excipients and Their Role in Insulin Stability and Association State in Formulation	17
Formulation of Lipid-Free Polymeric Mesoscale Nanoparticles Encapsulating mRNA	17
Pulmonary Delivery of Emerging Antibacterials for Bacterial Lung Infections Treatment	17
Identification of a Multi-Component Formulation for Intestinal Delivery of a GLP-1/Glucagon Co-agonist Peptide	17
Repurposing an Antiepileptic Drug for the Treatment of Glioblastoma	17
Correction: Development of a New Dry Powder Aerosol Synthetic Lung Surfactant Product for Neonatal Respiratory Distress Syndrome (RDS) – Part I: In Vitro Testing and Characterization	16
Cefmetazole as an Alternative to Carbapenems Against Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Infections Based on In Vitro and In Vivo Pharmacokinetics/Pharmacodynamics Experiments	16
Role of Charge Heterogeneity on Physical Stability of Monoclonal Antibody Biotherapeutic Products	16
Modeling Multiphase Heat and Mass Transfer in an Agitated Filter Dryer by Integrating Experiment, Computations, and Analytical Solutions	16
Development and Use of an Ex-Vivo In-Vivo Correlation to Predict Antiepileptic Drug Clearance in Patients Undergoing Continuous Renal Replacement Therapy	16
Exosomes as Carriers for Drug Delivery in Cancer Therapy	16
Dual Drug Loaded pH-sensitive Micelles for Efficient Bacterial Infection Treatment	15
Stable Atropine Loaded Film As a Potential Ocular Delivery System For Treatment Of Myopia	15
PBPK Analysis to Study the Impact of Genetic Polymorphism of NAT2 on Drug-Drug Interaction Potential of Isoniazid	15
Meta-Analysis of Drug Delivery Approaches for Treating Intracellular Infections	15
Solvent-Casted Films to Assist Polymer Selection for Amorphous Solid Dispersions During Preclinical Studies: In-vitro and In-vivo Exploration	15
Optimization of Initial Drug Distribution in Spherical Capsules for Personalized Release	15
Validation of Anti-Adeno Associated Virus Serotype rh10 (AAVrh.10) Total and Neutralizing Antibody Immunogenicity Assays	15
Dissolution Profiles of Carbamazepine Cocrystals with Cis–Trans Isomeric Coformers	15
TGF-β Signaling Activation Confers Anlotinib Resistance in Gastric Cancer	15
Spray-Congealing and Wet-Sieving as Alternative Processes for Engineering of Inhalation Carrier Particles: Comparison of Surface Properties, Blending and In Vitro Performance	15
Risk Assessment for a Twin-Screw Granulation Process Using a Supervised Physics-Constrained Auto-encoder and Support Vector Machine Framework	14
Rational Development of Stable PYY3–36 Peptide Y2 Receptor Agonists	14
Effect of Material Properties and Variability of Mannitol on Tablet Formulation Development	14
Expanding the toolbox for predictive parameters describing antibody stability considering thermodynamic and kinetic determinants	14
On the Applicability of the Coarse Grained Coupled CFD-DEM Model to Predict the Heat Transfer During the Fluidized Bed Drying of Pharmaceutical Granules	14
Enhancement of Docetaxel Absorption Using Ritonavir in an Oral Milk-Based Formulation	14
Engineering a Remedy to Modulate and Optimize Biopharmaceutical Properties of Rebamipide by Synthesizing New Cocrystal: In Silico and Experimental Studies	13
Correction to: Preparation and Preclinical Evaluation of Inhalable Particles Containing Rapamycin and Anti-Tuberculosis Agents for Induction of Autophagy	13
Brain Targeted Curcumin Loaded Turmeric Oil Microemulsion Protects Against Trimethyltin Induced Neurodegeneration in Adult Zebrafish: A Pharmacokinetic and Pharmacodynamic Insight	13
Incorporating Uremic Solute-mediated Inhibition of OAT1/3 Improves PBPK Prediction of Tenofovir Renal and Systemic Disposition in Patients with Severe Kidney Disease	13
Identification of the specific causes of polysorbate 20 degradation in monoclonal antibody formulations containing multiple lipases	13
Prediction of the Renal Organic Anion Transporter 1 (OAT1)- Mediated Drug Interactions for LY404039, the Active Metabolite of Pomaglumetad Methionil	13
Modeling Drug Dissolution in 3-Dimensional Space	13
Impact of Processing Methods on the Physico-chemical Properties of Posaconazole Amorphous Solid Dispersions	12
Review: Role of Model-Informed Drug Development Approaches in the Lifecycle of Drug Development and Regulatory Decision-Making	12
The Use of Physiologically Based Pharmacokinetic Analyses—in Biopharmaceutics Applications -Regulatory and Industry Perspectives	12
Use of Flory–Huggins Interaction Parameter and Contact Angle Values to Predict the Suitability of the Drug-Polymer System for the Production and Stability of Nanosuspensions	12
Professor Margareta Hammarlund-Udenaes – a Modern and Visionary Mentor	12
Professor David E. Smith: A Fearless Scientist and Devoted Mentor	12
Novel Deep Eutectic Solvent–Hydrogel Systems for Synergistic Transdermal Delivery of Chinese Herb Medicine and Local Treatments for Rheumatoid Arthritis	12
The pH Dependence of Niclosamide Solubility, Dissolution, and Morphology: Motivation for Potentially Universal Mucin-Penetrating Nasal and Throat Sprays for COVID19, its Variants and other Viral Infec	12
SNAC for Enhanced Oral Bioavailability: An Updated Review	12
Structure and Function of Cationic and Ionizable Lipids for Nucleic Acid Delivery	12
Professor Margareta Hammarlund-Udenaes - A Humble Scientist Shaping Modern Neuropharmacokinetics	12
Current State and Challenges of Physiologically Based Biopharmaceutics Modeling (PBBM) in Oral Drug Product Development	12
Effect of Fatty Acid Composition in Polysorbate 80 on the Stability of Therapeutic Protein Formulations	12
Stability of Protein Pharmaceuticals: Recent Advances	12
Correlative Image-Based Release Prediction and 3D Microstructure Characterization for a Long Acting Parenteral Implant	12
Female is Not First: the Gender Gap in Publishing Means More Needs to be Done	12
Mechanisms of Obesity-Induced Changes in Pharmacokinetics of IgG in Rats	11
Coupling Drug Dissolution with BCS	11
Proton-Coupled Oligopeptide Transport (Slc15) in the Brain: Past and Future Research	11
Minimal Physiologically-based Pharmacokinetic Model to Investigate the Effect of Charge on the Pharmacokinetics of Humanized anti-HCV-E2 IgG Antibodies in Sprague–Dawley Rats	11
Strategies To Stabilize Dalbavancin in Aqueous Solutions; Section 3: The Effects of 2 Hydroxypropyl-β-Cyclodextrin and Phosphate Buffer with and without Divalent Metal Ions	11
Nanoparticulate System Based on Calcium-Crosslinked Carbomer Retards Percutaneous Drug Permeation: New Insight Into Skin Barrier Functions	11
The Relationship Between Molecular Symmetry and Physicochemical Properties Involving Boiling and Melting of Organic Compounds	11
In vivo Pharmacokinetic/Pharmacodynamic Analysis of the Efficacy of the Cefepime/Nacubactam Combination Against β-Lactamase-Producing Enterobacterales based on the Instantaneous MIC Concept	11
Comparison of Relative Activity versus Relative Expression Factors (RAF versus REF) in Predicting Glucuronidation Mediated Drug Clearance Using Recombinant UGTs	11
The Critical Role of Equilibrative Nucleoside Transporter-2 in Modulating Cerebral Damage and Vascular Dysfunction in Mice with Brain Ischemia-Reperfusion	10
Enhanced Dermal Delivery of Flurbiprofen Nanosuspension Based Gel: Development and Ex Vivo Permeation, Pharmacokinetic Evaluations	10
Retraction Note: Codelivery of HIF-1α siRNA and Dinaciclib by Carboxylated Graphene Oxide-Trimethyl Chitosan-Hyaluronate Nanoparticles Significantly Suppresses Cancer Cell Progression	10
The Role of Artificial Intelligence and Machine Learning in Accelerating the Discovery and Development of Nanomedicine	10
Effect of P-glycoprotein and Cotreatment with Sofosbuvir on the Intestinal Permeation of Tenofovir Disoproxil Fumarate and Tenofovir Alafenamide Fumarate	10
Hollow Mesoporous Silica Nanoparticles for Dual Chemo-starvation Therapy of Hepatocellular Carcinoma	10
Clozapine-loaded nanocapsules improve antipsychotic activity in rats: building a sequential PopPK/PD model to discriminate nanocarriers in the preformulation step	10
Cortisol as Biomarker for CYP17-Inhibition is Associated with Therapy Outcome of Abiraterone Acetate	10
Targeted Drug Delivery for Chronic Lymphocytic Leukemia	10
Inhibitory Potential of the Truncated Isoforms on Glutamate Transporter Oligomerization Identified by Computational Analysis of Gene-Centric Isoform Maps	10

Correction: Practical Advice on Scientific Design of Freeze-Drying Process: 2023 Update	10
Conversion of Olmesartan to Olmesartan Medoxomil, A Prodrug that Improves Intestinal Absorption, Confers Substrate Recognition by OATP2B1	10
In Silico Dosimetry Study of Tc99m-Tetrofosmin in Children Using a Novel PBPK Model in Humans Built from SPECT Imaging Data	10
Population Pharmacokinetics of Flucloxacillin In Bone and Soft Tissue– Standard Dosing is Not Sufficient to Achieve Therapeutic Concentrations	10
Advancing Estimation of Hepatobiliary Clearances in Physiologically Based Pharmacokinetic Models of Rosuvastatin Using Human Hepatic Concentrations	10
Evaluation of In Vitro Metabolism- and Transporter-Based Drug Interactions with Sunscreen Active Ingredients	10
Rapid Synthesis and Evaluation of Resveratrol-Piperazine Cocrystals by Ultrasound and Microwave Methods	10
Tolterodine Tartrate Loaded Cationic Elastic Liposomes for Transdermal Delivery: In Vitro, Ex Vivo, and In Vivo Evaluations	10
Role of Tissue Hydraulic Permeability in Convection-Enhanced Delivery of Nanoparticle-Encapsulated Chemotherapy Drugs to Brain Tumour	9
Assessment of Cavitation Intensity in Accelerating Syringes of Spring-Driven Autoinjectors	9
Surfactant Protection Efficacy at Surfaces Varies with the Nature of Hydrophobic Materials	9
Engineering and Characterization of a Biomimetic Microchip for Differentiating Mouse Adipocytes in a 3D Microenvironment	9
Conditional Non-parametric Bootstrap for Non-linear Mixed Effect Models	9
Scaling Down Large-Scale Thawing of Monoclonal Antibody Solutions: 3D Temperature Profiles, Changes in Concentration, and Density Gradients	9
Uniformity and Efficacy of Dry Powders Delivered to the Lungs of a Mycobacterial-Surrogate Rat Model of Tuberculosis	9
Effect of Insulin Receptor-Knockdown on the Expression Levels of Blood–Brain Barrier Functional Proteins in Human Brain Microvascular Endothelial Cells	9
Micafungin Population PK Analysis in Healthy and Septic Pigs: Can the Septic Porcine Model Predict the Micafungin PK in Septic Patients?	9
Distribution Clearance: Significance and Underlying Mechanisms	9
Predictive Design and Analysis of Drug Transport by Multiscale Computational Models Under Uncertainty	9
Evaluation of Two Cosolvency Models to Predict Solute Partitioning between Polymers (LDPE) and Water - Ethanol Simulating Solvent Mixtures	9
Pharmacokinetics of CuGTSM, a Novel Drug Candidate, in a Mouse Model of Menkes Disease	9
Nanotechnology for Enhanced Cytoplasmic and Organelle Delivery of Bioactive Molecules to Immune Cells	9
A Novel Fluoro-Pyrazine-Bridged Donor-Accepter-Donor Fluorescent Probe for Lipid Droplet-Specific Imaging in Diverse Cells and Superoxide Anion Generation	9
Osmolality of Excipients for Parenteral Formulation Measured by Freezing Point Depression and Vapor Pressure – A Comparative Analysis	9
Gel Strength of Hydrophilic Matrix Tablets in Terms of In Vitro Robustness	9
Predicting Viable Skin Concentration: Modelling the Subpapillary Plexus	9
Raman Spectroscopic Analysis of Highly-Concentrated Antibodies under the Acid-Treated Conditions	9
The Use of Systemically Absorbed Drugs to Explore An In Vitro Bioequivalence Approach For Comparing Non-Systemically Absorbed Active Pharmaceutical Ingredients in Drug Products For Use in Dogs	9
RETRACTED ARTICLE: Combination Cancer Immunotherapy with Dendritic Cell Vaccine and Nanoparticles Loaded with Interleukin-15 and Anti-beta-catenin siRNA Significantly Inhibits Cancer Growth and Induce	9
Novel Self-Assembled Micelles With Increased Tumor Penetration and Anti-Tumor Efficiency Against Breast Cancer	9
Prediction of Oral Drug Absorption in Rats from In Vitro Data	9
Predicting Leachables Solubilization in Polysorbate 80 Solutions by a Linear Solvation Energy Relationship (LSER)	9
In Vitro - in Vivo Extrapolation of Hepatic Clearance in Preclinical Species	9
Midazolam Infusion and Disease Severity Affect the Level of Sedation in Children: A Parametric Time-to-Event Analysis	9
Re-writing Oral Pharmacokinetics Using Physiologically Based Finite Time Pharmacokinetic (PBFTPK) Models	9
Analysis of Non-linear Pharmacokinetics of P-Glycoprotein Substrates in a Microfluidic Device Using a Mathematical Model that Includes an Unstirred Water Layer (UWL) Compartment	9
Quantification of Unencapsulated Drug in Target Tissues Demonstrates Pharmacological Properties and Therapeutic Effects of Liposomal Topotecan (FF-10850)	9
Amphiphilic Ionic Liquids Capable to Formulate Organized Systems in an Aqueous Solution, Designed by a Combination of Traditional Surfactants and Commercial Drugs	9
Dissolution Profiles of Immediate Release Products of Various Drugs in Biorelevant Bicarbonate Buffer: Comparison with Compendial Phosphate Buffer	8
Process Modelling, Scale-Up and Characterization of Acetaminophen Spray Dried Milk Powder as Novel Pediatric Dosage Form	8
Mechanistic Study on the Effect of Renal Impairment on the Pharmacokinetics of Vildagliptin and its Carboxylic Acid Metabolite	8
Metal Ion Interactions with mAbs: Part 2. Zinc-Mediated Aggregation of IgG1 Monoclonal Antibodies	8
General Commentary: A Tribute to Professor Kenneth R. Morris – Scientist, Teacher, Mentor, Friend…and Underappreciated Academic Arborist	8
Droplet-Based Microfluidic Tool to Quantify Viscosity of Concentrating Protein Solutions	8
Co-Delivery of D-LAK Antimicrobial Peptide and Capreomycin as Inhaled Powder Formulation to Combat Drug-Resistant Tuberculosis	8
Investigation of Dispersion Kinetics of Particulate Lubricants and their Effect on the Mechanical Strength of MCC Tablets	8
Pharmacokinetic/Pharmacodynamic Modeling of a Cell-Penetrating Peptide Phosphorodiamidate Morpholino Oligomer in mdx Mice	8
Transdermal Delivery of Metformin Utilizing Ionic Liquid Technology: Insight Into the Relationship Between Counterion Structures and Properties	8
Identification and Activity Study of an Impurity Band Observed in the nrSDS-PAGE of Aflibercept	8
Accelerated Development of Pharmaceuticals Past, Present, and Future	8
Role of Disease Progression Models in Drug Development	8
Assessing the Impact of Punch Geometries on Tablet Capping Using a Newly Proposed Capping Index	8
Antibody-Targeted Liposomes for Enhanced Targeting of the Blood-Brain Barrier	8
Translational Modeling of Chloroquine and Hydroxychloroquine Dosimetry in Human Airways for Treating Viral Respiratory Infections	8
Development of a Prototype, Once-Daily, Modified-Release Formulation for the Short Half-Life RIPK1 Inhibitor GSK2982772	8
Prediction of the Mechanical Deformation Properties of Organic Crystals Based upon their Crystallographic Structures: Case Studies of Pentaerythritol and Pentaerythritol Tetranitrate	8
Treprostinil Supplementation Ameliorates Hepatic Ischemia Reperfusion Injury and Regulates Expression of Hepatic Drug Transporters: An Isolated Perfused Rat Liver (IPRL) Study	8
Delivery of Corn-Derived Nanoparticles with Anticancer Activity to Tumor Tissues by Modification with Polyethylene Glycol for Cancer Therapy	8
Clinical Ocular Exposure Extrapolation for Ophthalmic Solutions Using PBPK Modeling and Simulation	8
Photo-Oxidation Mechanisms in Liquid Pharmaceutical Formulations: The Overlooked Role of Singlet Oxygen Presented as a Case Study	8
In-Vivo and Ex-Vivo Brain Uptake Studies of Peptidomimetic Neurolysin Activators in Healthy and Stroke Animals	8
Multiphysics Simulation in Drug Development and Delivery	8